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Conserved domains on  [gi|489746009|ref|WP_003650029|]
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MULTISPECIES: DUF3290 domain-containing protein [Lactobacillus]

Protein Classification

DUF3290 domain-containing protein( domain architecture ID 10569469)

uncharacterized DUF3290 domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF3290 pfam11694
Protein of unknown function (DUF3290); This family of proteins with unknown function appears ...
 2-147 2.76e-57

Protein of unknown function (DUF3290); This family of proteins with unknown function appears to be restricted to Firmicutes.


:

Pssm-ID: 432006  Cd Length: 144  Bit Score: 175.11  E-value: 2.76e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489746009    2 NFYTINYIQSHQNTDRTALYILMIVAASAMIIFTILYLRDRFNTRYRDLGIIALLFLVLFAGTQYEKYIQNNEQKSKAAQ 81
Cdd:pfam11694   1 TFYTYNYLQNQANSNDYLRYILIFALLLALIIFFILYLRNRIDTKYRDLSIILLLLLLLLLGIQYSQYQQNQSASSQTSQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489746009   82 IVPFIKSIADDANVKKSDVMVSSTTLQDGMIIRIDskNEDYQLNLNEDNNSYTLTRAHVIDHHVYV 147
Cdd:pfam11694  81 MTSFIKNVAEELKVSKKDVLVNSTSLSDGMIVKID--DKYYQVNLNSDNNSYTLEKTHLINSKIKI 144
 
Name Accession Description Interval E-value
DUF3290 pfam11694
Protein of unknown function (DUF3290); This family of proteins with unknown function appears ...
 2-147 2.76e-57

Protein of unknown function (DUF3290); This family of proteins with unknown function appears to be restricted to Firmicutes.


Pssm-ID: 432006  Cd Length: 144  Bit Score: 175.11  E-value: 2.76e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489746009    2 NFYTINYIQSHQNTDRTALYILMIVAASAMIIFTILYLRDRFNTRYRDLGIIALLFLVLFAGTQYEKYIQNNEQKSKAAQ 81
Cdd:pfam11694   1 TFYTYNYLQNQANSNDYLRYILIFALLLALIIFFILYLRNRIDTKYRDLSIILLLLLLLLLGIQYSQYQQNQSASSQTSQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489746009   82 IVPFIKSIADDANVKKSDVMVSSTTLQDGMIIRIDskNEDYQLNLNEDNNSYTLTRAHVIDHHVYV 147
Cdd:pfam11694  81 MTSFIKNVAEELKVSKKDVLVNSTSLSDGMIVKID--DKYYQVNLNSDNNSYTLEKTHLINSKIKI 144
MFS_ShiA_like cd17369
Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This ...
 1-62 1.36e-03

Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.


Pssm-ID: 340927 [Multi-domain]  Cd Length: 408  Bit Score: 37.51  E-value: 1.36e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489746009   1 MNFYTINYIQSHQNTDRTALYILMIVAASAMIIFTIL--YLRDRFNTR--YrdlgIIALLFLVLFA 62
Cdd:cd17369  247 FTTFALSYATQTLGVDRSTVLLAVLIASVVAAITIPLfgWLSDRVGRRpvY----LAGALLAALFA 308
 
Name Accession Description Interval E-value
DUF3290 pfam11694
Protein of unknown function (DUF3290); This family of proteins with unknown function appears ...
 2-147 2.76e-57

Protein of unknown function (DUF3290); This family of proteins with unknown function appears to be restricted to Firmicutes.


Pssm-ID: 432006  Cd Length: 144  Bit Score: 175.11  E-value: 2.76e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489746009    2 NFYTINYIQSHQNTDRTALYILMIVAASAMIIFTILYLRDRFNTRYRDLGIIALLFLVLFAGTQYEKYIQNNEQKSKAAQ 81
Cdd:pfam11694   1 TFYTYNYLQNQANSNDYLRYILIFALLLALIIFFILYLRNRIDTKYRDLSIILLLLLLLLLGIQYSQYQQNQSASSQTSQ 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489746009   82 IVPFIKSIADDANVKKSDVMVSSTTLQDGMIIRIDskNEDYQLNLNEDNNSYTLTRAHVIDHHVYV 147
Cdd:pfam11694  81 MTSFIKNVAEELKVSKKDVLVNSTSLSDGMIVKID--DKYYQVNLNSDNNSYTLEKTHLINSKIKI 144
MFS_ShiA_like cd17369
Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This ...
 1-62 1.36e-03

Shikimate transporter and similar proteins of the Major Facilitator Superfamily; This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.


Pssm-ID: 340927 [Multi-domain]  Cd Length: 408  Bit Score: 37.51  E-value: 1.36e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489746009   1 MNFYTINYIQSHQNTDRTALYILMIVAASAMIIFTIL--YLRDRFNTR--YrdlgIIALLFLVLFA 62
Cdd:cd17369  247 FTTFALSYATQTLGVDRSTVLLAVLIASVVAAITIPLfgWLSDRVGRRpvY----LAGALLAALFA 308
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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