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Conserved domains on  [gi|489748068|ref|WP_003652077|]
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MULTISPECIES: F0F1 ATP synthase subunit A [Lactobacillus]

Protein Classification

FoF1 ATP synthase subunit a( domain architecture ID 10012597)

FoF1 ATP synthase subunit a is part of the membrane proton channel of the F-type ATPase that produces ATP from ADP in the presence of a proton gradient across the membrane; it plays a direct role in the translocation of protons across the membrane

Gene Ontology:  GO:0045263|GO:0046933|GO:0005886
PubMed:  28001127

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 8-238 6.71e-60

F0F1 ATP synthase subunit A; Validated


:

Pssm-ID: 235617  Cd Length: 227  Bit Score: 188.08  E-value: 6.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   8 VNVFGLNFNVTNCLGGTLVAIAVFFLVWYLG-RNISLKPNKKQNLLEYLIDFTNGIVKDNVADvdAQKHLSLYAFTLFMF 86
Cdd:PRK05815   5 LIIGFGGFNFDSLLLSVLLGVLILLLFALVAtRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGG--KGKKFAPLAFTLFLF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  87 IFFMNQLGLFFefsindhILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-YAKPVGFLLPINIIEEFTNFL 165
Cdd:PRK05815  83 ILLMNLLGLIP-------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISEFSRPI 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489748068 166 TLSLRLYGNIYAGEVLLTLIGgrFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIGKKVTEE 238
Cdd:PRK05815 156 SLSLRLFGNMLAGELILALIA--LLGGAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 8-238 6.71e-60

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 188.08  E-value: 6.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   8 VNVFGLNFNVTNCLGGTLVAIAVFFLVWYLG-RNISLKPNKKQNLLEYLIDFTNGIVKDNVADvdAQKHLSLYAFTLFMF 86
Cdd:PRK05815   5 LIIGFGGFNFDSLLLSVLLGVLILLLFALVAtRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGG--KGKKFAPLAFTLFLF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  87 IFFMNQLGLFFefsindhILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-YAKPVGFLLPINIIEEFTNFL 165
Cdd:PRK05815  83 ILLMNLLGLIP-------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISEFSRPI 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489748068 166 TLSLRLYGNIYAGEVLLTLIGgrFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIGKKVTEE 238
Cdd:PRK05815 156 SLSLRLFGNMLAGELILALIA--LLGGAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 25-237 4.68e-52

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 167.56  E-value: 4.68e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  25 LVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVaDVDAQKHLSlYAFTLFMFIFFMNQLGLFFEFsindh 104
Cdd:COG0356    8 LAMLLLLLLFLLATRKLKLVPGGLQNFVEMLVEFVRNQVKDTI-GKKGRKFAP-LLLTLFLFILVSNLLGLIPGL----- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 105 ilvKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-YAKPVG----FLLPINIIEEFTNFLTLSLRLYGNIYAGE 179
Cdd:COG0356   81 ---FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHlFFPPFPwlapLMLPIEIISELARPLSLSLRLFGNMFAGH 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489748068 180 VLLTLIGGrFAKSAGWFtvIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIGKKVTE 237
Cdd:COG0356  158 IILLLLAG-LAPFLLLG--VLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
25-232 4.86e-51

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 165.36  E-value: 4.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   25 LVAIAVFFLVWYLGRNIS-LKPNKKQNLLEYLIDFTNGIVKDNVADVDAQKHLsLYAFTLFMFIFFMNQLGLFFEFsind 103
Cdd:pfam00119   6 IVALILLLFLLLATRKTKkLVPGRLQNFVEMLVEFVDNIVKDNIGKKKGRKFF-PLLLTLFFFILVSNLLGLIPKS---- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  104 hILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFANYAKP------VGFLLPINIIEEFTNFLTLSLRLYGNIYA 177
Cdd:pfam00119  81 -PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFVPpvplplVPLLLPIEIISEFARPVSLSLRLFGNMLA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 489748068  178 GEVLLTLIGG--RFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIG 232
Cdd:pfam00119 160 GHLLLLLLAGliFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 74-232 2.14e-31

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 112.88  E-value: 2.14e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  74 KHLSLYAFTLFMFIFFMNQLGLFFefsindhiLVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-----YAKP 148
Cdd:cd00310    2 KKYLPLLGTLFLFILFSNLLGLIP--------YSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFlppgtPLPL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 149 VGFLLPINIIEEFTNFLTLSLRLYGNIYAGEVLLTLIGGrFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSM 228
Cdd:cd00310   74 APLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSG-LVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTA 152


                 ....
gi 489748068 229 VYIG 232
Cdd:cd00310  153 VYIS 156
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 24-231 3.51e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.23  E-value: 3.51e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   24 TLVAIAVFFLVWYLGRNIslKPNKKQNLLEYLIDFTNGIVKDNVADvdAQKHLSLYAFTLFMFIFFMNQLGLFFefsind 103
Cdd:TIGR01131  22 LLLSLLIFLISSSLSRWL--IPSRWQNLMESIYEFVLSIVKSQIGG--KKGKFFPLIFTLFLFILISNLLGLIP------ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  104 hiLVKSPTANPLITMTMAMMTLLLSYNFGVQK--FGAKGYFANYAKPVG---FLLPINIIEEFTNFLTLSLRLYGNIYAG 178
Cdd:TIGR01131  92 --YSFTPTSHLSFTLGLALPLWLGLTISGFRKhpKGFLAHLVPSGTPLPlipFLVIIETISYLARPISLSVRLFANISAG 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 489748068  179 EVLLTLIGGRFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYI 231
Cdd:TIGR01131 170 HLLLTLLSGLLFSLMSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYL 222
 
Name Accession Description Interval E-value
PRK05815 PRK05815
F0F1 ATP synthase subunit A; Validated
 8-238 6.71e-60

F0F1 ATP synthase subunit A; Validated


Pssm-ID: 235617  Cd Length: 227  Bit Score: 188.08  E-value: 6.71e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   8 VNVFGLNFNVTNCLGGTLVAIAVFFLVWYLG-RNISLKPNKKQNLLEYLIDFTNGIVKDNVADvdAQKHLSLYAFTLFMF 86
Cdd:PRK05815   5 LIIGFGGFNFDSLLLSVLLGVLILLLFALVAtRKLSGVPGGLQNFVEMIVEFVRGQVKDNIGG--KGKKFAPLAFTLFLF 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  87 IFFMNQLGLFFefsindhILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-YAKPVGFLLPINIIEEFTNFL 165
Cdd:PRK05815  83 ILLMNLLGLIP-------YLLFPPTADINVTLALALIVFVLVIYYGIKKKGLGGYLKEfYLQPHPLLLPIEIISEFSRPI 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489748068 166 TLSLRLYGNIYAGEVLLTLIGgrFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIGKKVTEE 238
Cdd:PRK05815 156 SLSLRLFGNMLAGELILALIA--LLGGAGLLLALAPLILPVAWTIFEIFVGTLQAYIFMMLTIVYISMAVEEE 226
AtpB COG0356
FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP ...
 25-237 4.68e-52

FoF1-type ATP synthase, membrane subunit a [Energy production and conversion]; FoF1-type ATP synthase, membrane subunit a is part of the Pathway/BioSystem: FoF1-type ATP synthase


Pssm-ID: 440125 [Multi-domain]  Cd Length: 212  Bit Score: 167.56  E-value: 4.68e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  25 LVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVaDVDAQKHLSlYAFTLFMFIFFMNQLGLFFEFsindh 104
Cdd:COG0356    8 LAMLLLLLLFLLATRKLKLVPGGLQNFVEMLVEFVRNQVKDTI-GKKGRKFAP-LLLTLFLFILVSNLLGLIPGL----- 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 105 ilvKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-YAKPVG----FLLPINIIEEFTNFLTLSLRLYGNIYAGE 179
Cdd:COG0356   81 ---FPPTADINVTLALALIVFVLVHYYGIKKKGLGGYLKHlFFPPFPwlapLMLPIEIISELARPLSLSLRLFGNMFAGH 157

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489748068 180 VLLTLIGGrFAKSAGWFtvIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIGKKVTE 237
Cdd:COG0356  158 IILLLLAG-LAPFLLLG--VLSLLLPVAWTAFELLVGFLQAYIFTMLTAVYISLAVEE 212
ATP-synt_A pfam00119
ATP synthase A chain;
25-232 4.86e-51

ATP synthase A chain;


Pssm-ID: 459679 [Multi-domain]  Cd Length: 216  Bit Score: 165.36  E-value: 4.86e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   25 LVAIAVFFLVWYLGRNIS-LKPNKKQNLLEYLIDFTNGIVKDNVADVDAQKHLsLYAFTLFMFIFFMNQLGLFFEFsind 103
Cdd:pfam00119   6 IVALILLLFLLLATRKTKkLVPGRLQNFVEMLVEFVDNIVKDNIGKKKGRKFF-PLLLTLFFFILVSNLLGLIPKS---- 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  104 hILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFANYAKP------VGFLLPINIIEEFTNFLTLSLRLYGNIYA 177
Cdd:pfam00119  81 -PGGFTVTADINVTLALALIVFLLVHYYGIKKHGLGGYFKKLFVPpvplplVPLLLPIEIISEFARPVSLSLRLFGNMLA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 489748068  178 GEVLLTLIGG--RFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIG 232
Cdd:pfam00119 160 GHLLLLLLAGliFALLSAGFLLGVIPPLLGVAWTLFELLVAFIQAYVFTMLTAVYIS 216
ATP-synt_Fo_a_6 cd00310
ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms ...
 74-232 2.14e-31

ATP synthase Fo complex, subunit 6 (eukaryotes) and subunit a (prokaryotes); Bacterial forms are designated as ATP synthase, Fo complex, subunit a; eukaryotic (chloroplast and mitochondrial) forms are designated as ATP synthase, Fo complex, subunit 6. The F-ATP synthases (also called FoF1-ATPases) consist of two structural domains: F1 (factor one) complex containing the soluble catalytic core, and Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. F-ATP synthase has also been found in the archaea Methanosarcina acetivorans. F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis.


Pssm-ID: 349411 [Multi-domain]  Cd Length: 156  Bit Score: 112.88  E-value: 2.14e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  74 KHLSLYAFTLFMFIFFMNQLGLFFefsindhiLVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFAN-----YAKP 148
Cdd:cd00310    2 KKYLPLLGTLFLFILFSNLLGLIP--------YSFTPTSHLNVTLALALIVFLGVHILGIKKHGLGFFLHFlppgtPLPL 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 149 VGFLLPINIIEEFTNFLTLSLRLYGNIYAGEVLLTLIGGrFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSM 228
Cdd:cd00310   74 APLMVPIELISELIRPLSLSVRLFANMFAGHLLLALLSG-LVPSLLSSVGLLPLLLPVALTLLELFVAFIQAYVFTLLTA 152


                 ....
gi 489748068 229 VYIG 232
Cdd:cd00310  153 VYIS 156
ATP_synt_6_or_A TIGR01131
ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be ...
 24-231 3.51e-31

ATP synthase subunit 6 (eukaryotes),also subunit A (prokaryotes); Bacterial forms should be designated ATP synthase, F0 subunit A; eukaryotic (chloroplast and mitochondrial) forms should be designated ATP synthase, F0 subunit 6. The F1/F0 ATP synthase is a multisubunit, membrane associated enzyme found in bacteria and mitochondria and chloroplast. This enzyme is principally involved in the synthesis of ATP from ADP and inorganic phosphate by coupling the energy derived from the proton electrochemical gradient across the biological membrane. A brief description of this multisubunit enzyme complex: F1 and F0 represent two major clusters of subunits. Individual subunits in each of these clusters are named differently in prokaryotes and in organelles e.g., mitochondria and chloroplast. The bacterial equivalent of subunit 6 is named subunit 'A'. It has been shown that proton is conducted though this subunit. Typically, deprotonation and reprotonation of the acidic amino acid side-chains are implicated in the process. [Energy metabolism, ATP-proton motive force interconversion]


Pssm-ID: 273458  Cd Length: 226  Bit Score: 114.23  E-value: 3.51e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068   24 TLVAIAVFFLVWYLGRNIslKPNKKQNLLEYLIDFTNGIVKDNVADvdAQKHLSLYAFTLFMFIFFMNQLGLFFefsind 103
Cdd:TIGR01131  22 LLLSLLIFLISSSLSRWL--IPSRWQNLMESIYEFVLSIVKSQIGG--KKGKFFPLIFTLFLFILISNLLGLIP------ 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  104 hiLVKSPTANPLITMTMAMMTLLLSYNFGVQK--FGAKGYFANYAKPVG---FLLPINIIEEFTNFLTLSLRLYGNIYAG 178
Cdd:TIGR01131  92 --YSFTPTSHLSFTLGLALPLWLGLTISGFRKhpKGFLAHLVPSGTPLPlipFLVIIETISYLARPISLSVRLFANISAG 169

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|...
gi 489748068  179 EVLLTLIGGRFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYI 231
Cdd:TIGR01131 170 HLLLTLLSGLLFSLMSSAIFALLLLILVALIILEIFVAFIQAYVFTLLTCLYL 222
atpI CHL00046
ATP synthase CF0 A subunit
 24-232 1.63e-28

ATP synthase CF0 A subunit


Pssm-ID: 176987  Cd Length: 228  Bit Score: 107.33  E-value: 1.63e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  24 TLVAIAVFFLVWYLG-RNISLKPNKKQNLLEYLIDFTNGIVKDNVADVDAQKHLSlYAFTLFMFIFFMNQLGLFFEFSIN 102
Cdd:CHL00046  29 SWVVIAILLGSALLAtRNLQTIPTGGQNFFEYVLEFIRDLAKTQIGEEEYRPWVP-FIGTMFLFIFVSNWSGALLPWKLI 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 103 D--HILVKSPTANPLITMTMAMMTLLLSYNFGVQKFGAkGYFANYAKPVGFLLPINIIEEFTNFLTLSLRLYGNIYAGE- 179
Cdd:CHL00046 108 ElpHGELAAPTNDINTTVALALLTSVAYFYAGLSKKGL-GYFGKYIQPTPILLPINILEDFTKPLSLSFRLFGNILADEl 186

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489748068 180 ---VLLTLiggrfaksagwftVIASVPLTLIWQGfsVFIGSIQAYVFVTLSMVYIG 232
Cdd:CHL00046 187 vvaVLVSL-------------VPLVVPIPVMFLG--LFTSGIQALIFATLAAAYIG 227
PRK13421 PRK13421
F0F1 ATP synthase subunit A; Provisional
 35-237 1.79e-24

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237383  Cd Length: 223  Bit Score: 96.69  E-value: 1.79e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  35 WYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVAdVDAQKHLSLYAfTLFMFIFFMNQLGLFFEfsindhilVKSPTANP 114
Cdd:PRK13421  38 ALATRRLSLAPGRLQSVLELVVTTIDAQIRDTMQ-TDPAPYRALIG-TLFLFVLVANWSSLVPG--------VEPPTAHL 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 115 LITMTMAMMTLLLSYNFGVQKFGAKGYFANYAKPVGFLLPINIIEEFTNFLTLSLRLYGNIYAGEVLLTLIggrfAKSAG 194
Cdd:PRK13421 108 ETDAALALIVFLATIYYGVRARGVRGYLATFAEPTWVMIPLNLVEQLTRTFSLIVRLFGNVMSGVFVIGIV----LSLAG 183

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 489748068 195 WFtviasVPLTLIwqGFSVFIGSIQAYVFVTLSMVYIGKKVTE 237
Cdd:PRK13421 184 LL-----VPIPLM--ALDLLTGAVQAYIFAVLAMVFIGAAVSD 219
PRK13419 PRK13419
F0F1 ATP synthase subunit A; Provisional
 28-232 5.02e-20

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237381  Cd Length: 342  Bit Score: 87.11  E-value: 5.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  28 IAVFFLV--WYLGRNISLKPNKKQNLLEYLIDFT-NGIVKDNVAdVDAQKHLSlYAFTLFMFIFFMNQLGLfFEFSindh 104
Cdd:PRK13419 121 LVVFLAAgrKYKKMTKSQAPKGLANAMEALVEFIrLDVAKSNIG-HGYEKFLP-YLLTVFFFILVCNLLGL-VPYG---- 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 105 ilvKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFANYAKPVGFLL-----PINIIEEFTNFLTLSLRLYGNIYAGE 179
Cdd:PRK13419 194 ---ATATGNINVTLTLAVFTFFITQYAAIKAHGIKGYLAHLTGGTHWSLwiimiPIEFIGLFTKPFALTVRLFANMTAGH 270

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489748068 180 -VLLTLIGGRFAKSAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVTLSMVYIG 232
Cdd:PRK13419 271 iVILSLIFISFILKSYIVAVAVSVPFAIFIYLLELFVAFLQAYIFTMLSALFIG 324
PRK13420 PRK13420
F0F1 ATP synthase subunit A; Provisional
 25-231 1.27e-19

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237382 [Multi-domain]  Cd Length: 226  Bit Score: 84.02  E-value: 1.27e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  25 LVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFtngiVKDNVADVDAQKHLSLYAF--TLFMFIFFMNQLGLFFEFsin 102
Cdd:PRK13420  25 GIMIVLVLASWLTTRRLSLDPGRFQVALEGVVST----IEDAIKEVLPRHARLVLPFvgTLWIFILVANLIGLIPGF--- 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 103 dhilvKSPTANPLITMTMAMMTLLLSYNFGVQKFGAKGYFANYAKPVGFLLPINIIEEFTNFLTLSLRLYGNIYAGEV-- 180
Cdd:PRK13420  98 -----HSPTADLSVTAALALLVFFSVHWFGIRAEGLREYLKHYLSPSPFLLPFHLISEITRTLALAVRLFGNIMSLELaa 172

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489748068 181 -LLTLIGGRFaksagwftviASVPLTLIwqgfSVFIGSIQAYVFVTLSMVYI 231
Cdd:PRK13420 173 lLVLLVAGFL----------VPVPILML----HIIEALVQAYIFGMLALIYI 210
ATP6 MTH00173
ATP synthase F0 subunit 6; Provisional
 76-230 1.11e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214448  Cd Length: 231  Bit Score: 53.72  E-value: 1.11e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  76 LSLYAFTLFMFIFFMNQLGLFfefsindhILVKSPTANPLITMTMA----MMTLLLSYNFGVQKFGAKGYFAnyAKPVG- 150
Cdd:MTH00173  71 FSLLLSSLFLFLISLNLSGLL--------PFVFSVTSHLAFTFSLAlplwLSLILSGLFYNPSKSLAGLVPA--GAPAGl 140

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 151 --FLLPINIIEEFTNFLTLSLRLYGNIYAGEVLLTLIGGRFAK---SAGWFTVIASVPLTLIWQGFSVFIGSIQAYVFVT 225
Cdd:MTH00173 141 npFLVLIETVSILIRPLTLTVRLLANISAGHIVLTLIGNYLSSslfSSSVVSLLLVLLIQVGYFIFEVAVMLIQAYIFTL 220


                 ....*
gi 489748068 226 LSMVY 230
Cdd:MTH00173 221 LIKLY 225
ATP6 MTH00172
ATP synthase F0 subunit 6; Provisional
 15-232 1.38e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214447  Cd Length: 232  Bit Score: 53.51  E-value: 1.38e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  15 FNVTNCLGGT---LVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVAdVDAQKHLSLYaFTLFMFIFFMN 91
Cdd:MTH00172   9 FNIVWLIGLTnssIMMILVIIVVLLLFKGIKLIPKRWQSIIEIIYNHFHGVVKDNLG-NEGLKYFPFI-ISLFFFIVFLN 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  92 QLGLFfefsindhILVKSPTANPLITMTMAMMTLLLSYNFGVQKFgaKGYFANYAKPVG-------FLLPINIIEEFTNF 164
Cdd:MTH00172  87 LLGLF--------PYVFTPTTHIVVTLGLSFSIIIGVTLAGFWRF--KWDFFSILMPSGaplglapLLVLIETVSYISRA 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489748068 165 LTLSLRLYGNIYAGEVLLTLIGG------RFAKSAGWFTVIASVPLTLIWQGFSVfigsIQAYVFVTLSMVYIG 232
Cdd:MTH00172 157 ISLGVRLAANLSAGHLLFAILAGfgfnmlCASGFLSLFPLLIMVFITLLEIAVAV----IQAYVFCLLTTIYLA 226
PRK13417 PRK13417
F0F1 ATP synthase subunit A; Provisional
 10-232 2.16e-08

F0F1 ATP synthase subunit A; Provisional


Pssm-ID: 237380  Cd Length: 352  Bit Score: 53.74  E-value: 2.16e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  10 VFGLNFNVTNCLGGTLVAIAVFFLVWYLGRN-ISLKPNKKQNLLEYLIDFTNGIVKDNVADVDAQKH---LSLYAFTLFM 85
Cdd:PRK13417  87 VGGFDMHITKRVTMMWIVAFFLFLIFIPAANiIAKNPLKVQSRFANTVEVFVNFLRKDIVDESMHGHghsYYHYIFTLFF 166

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  86 FIFFMNQLGLF----------------------FEFSINDHILVK-----SPTANPLITMTMAMMTLLLSYNFGVQKFGA 138
Cdd:PRK13417 167 FILFCNLMGLVpsvgeltvvasdygglvalgvmDHTPHALPTFAKvwsgiTVTGDISVTMTLALLTMFLIYGAGFSYQGP 246

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 139 KgyFANYAKPVGFLLPINIIEEFTNFLT--------LSLRLYGNIYAGEVLLTLIGGRFAKSAGWFTVIASVPLTLIWQG 210
Cdd:PRK13417 247 K--FIWHSVPNGVPLLLYPIMWPLEFIVspmaktfaLTVRLLANMTAGHVIILALMGFIFQFQSWGIVPVSVIGSGLIYV 324

                        250       260
                 ....*....|....*....|..
gi 489748068 211 FSVFIGSIQAYVFVTLSMVYIG 232
Cdd:PRK13417 325 LEIFVAFLQAYIFVLLTSLFVG 346
ATP6 MTH00175
ATP synthase F0 subunit 6; Provisional
 24-232 4.34e-08

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177228  Cd Length: 244  Bit Score: 52.32  E-value: 4.34e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  24 TLVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVADVdAQKHLSlYAFTLFMFIFFMNQLGLFfefsind 103
Cdd:MTH00175  32 SMMMVLAVIIFWLLLKGDKLIPNRWQSIMELIYLNIRSVVHDNLGKS-GQKYFP-FILSLFLFIAILNILGLF------- 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 104 hILVKSPTANPLITMTMAMMTLLLSYNFGVQKFgaKGYFANYAKPVG-------FLLPINIIEEFTNFLTLSLRLYGNIY 176
Cdd:MTH00175 103 -PYVFTPTAHIIITFGLSLSIIIAVTLLGFLTF--KWNFLSILMPGGaplvlapFLVLIETLSYLIRAISLGVRLAANIS 179

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489748068 177 AGEVLLTLIGG-RFAKSAGWFTVIASVPLTLIwqgfsVFI-------GSIQAYVFVTLSMVYIG 232
Cdd:MTH00175 180 AGHLLFAILSGfAFNMLSNGLIILSLFPMLIM-----IFItllemavAVIQAYVFCLLTTIYLG 238
ATP6 MTH00157
ATP synthase F0 subunit 6; Provisional
 73-231 1.04e-07

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214441  Cd Length: 223  Bit Score: 50.94  E-value: 1.04e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  73 QKHLSLYAFTLFMFIFFMNQLGLFFefsindhiLVKSPTANPLITMTMAmMTLLLSYNFgvqkfgaKGYFANYAKPVGFL 152
Cdd:MTH00157  65 NKGSTLIFISLFSFILFNNFLGLFP--------YIFTSTSHLSLTLSLA-LPLWLSFML-------FGWINNTNHMFAHL 128

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 153 LPIN----------IIEEFTNF---LTLSLRLYGNIYAGEVLLTLIGGRFAKSAGWFTVIaSVPLTLIWQGFSVFIGSIQ 219
Cdd:MTH00157 129 VPQGtppilmpfmvLIETISNLirpGTLAVRLAANMIAGHLLLTLLGNTGPSLSSMILSI-LILIQILLLILESAVAIIQ 207

                        170
                 ....*....|..
gi 489748068 220 AYVFVTLSMVYI 231
Cdd:MTH00157 208 SYVFSVLSTLYS 219
ATP6 MTH00005
ATP synthase F0 subunit 6; Provisional
 82-230 1.34e-06

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 164583  Cd Length: 231  Bit Score: 47.81  E-value: 1.34e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  82 TLFMFIFFMNQLGLF-FEFSINDHILVKSPTANPLitmTMAMMTLLLSYNFgvQKFGAK---GYFANYAKPvgFLLPINI 157
Cdd:MTH00005  79 ALFTMIILMNLSGLLpYVFSTSSHLIFTLTLGLPL---WLSLIMSSVTFSP--KKFAAHllpGGAPDWLNP--FLVLIET 151

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489748068 158 IEEFTNFLTLSLRLYGNIYAGEVLLTLIGGRFAksAGWFTVIASVPLTLIWQGFSVF----IGSIQAYVFVTLSMVY 230
Cdd:MTH00005 152 ISILVRPITLSFRLAANMSAGHIVLSLIGIYAA--SALFSSISSTILLILTQMGYILfevgICLIQAYIFCLLLSLY 226
ATP6 MTH00176
ATP synthase F0 subunit 6; Provisional
 81-230 1.96e-04

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 214449  Cd Length: 229  Bit Score: 41.17  E-value: 1.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  81 FTLFMFIFFMNQLGLFfefsindhILVKSPTANPLITMTMAMmTLLLSYNFGVQKFGAKGYFANYAkPVG-------FLL 153
Cdd:MTH00176  76 ISLFILVMSLNLSGLI--------PYVFTSTSHLVITLSLAL-PLWLGVILSGFINNFYSRLSHLV-PQGtppllnpFLV 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068 154 PINIIEEFTNFLTLSLRLYGNIYAGEVLLTLIGGRFAK----SAGWFTVIASVPLTLIWqgFSVFIGSIQAYVFVTLSMV 229
Cdd:MTH00176 146 LIELVSLLIRPLTLAVRLAANLSAGHLLLGLLGAAMWGllpvSPLIGFLLLIVQILYFM--FEIAVCMIQAYVFTLLLSL 223


                 .
gi 489748068 230 Y 230
Cdd:MTH00176 224 Y 224
ATP6 MTH00179
ATP synthase F0 subunit 6; Provisional
 81-230 2.60e-04

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 177230  Cd Length: 227  Bit Score: 41.09  E-value: 2.60e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  81 FTLFMFIFFMNQLGLF-FEFsindhilvkSPTANPLITMTMAMMTLLLSYNFGVQKF--GAKGYFANYAKP---VGFLLP 154
Cdd:MTH00179  74 LSLMLFLLTLNLLGLLpYTF---------TPTTQLSLNLGLALPLWLGTVLYGLFNQptIALAHLLPEGTPtplIPMLVW 144

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489748068 155 INIIEEFTNFLTLSLRLYGNIYAGEVLLTLIG-GRFAKSAGWFTVIASVPLTLIWQGF-SVFIGSIQAYVFVTLSMVY 230
Cdd:MTH00179 145 IETISLLIRPLALGVRLTANITAGHLLMHLISsAVFVLMNFMGMVALLTLLVLFLLTLlEVAVAMIQAYVFVLLLSLY 222
ATP6 MTH00174
ATP synthase F0 subunit 6; Provisional
 15-235 5.03e-03

ATP synthase F0 subunit 6; Provisional


Pssm-ID: 133799  Cd Length: 252  Bit Score: 37.23  E-value: 5.03e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  15 FNVTNCLGGTLVAIAVFFLVWYLGRNISLKPNKKQNLLEYLIDFTNGIVKDNVADVDAqkHLSLYAFTLFMFIFFMNQLG 94
Cdd:MTH00174  31 FCFTNTFFMMSFAVFLFYTIGAKGNNNTLVPNRILVGLELIYSHFYTVLKDNLGNKGG--NYLAFVLSLFILILFGNGLG 108

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489748068  95 LFfefsindhILVKSPTANPLITMTMAMMTLLLSYNFGVQKFgaKGYFANYAKPVG-------FLLPINIIEEFTNFLTL 167
Cdd:MTH00174 109 LF--------PYVFTPTVHMVITLGLSFAIIVGTTLAGLITF--RFNFFSILMPQGaplalapLLTIIETLSYISRAISL 178

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489748068 168 SLRLYGNIYAGEVLLTLIGGRFAKSAGWFTVIAS-VPLTLIW--QGFSVFIGSIQAYVFVTLSMVYIGKKV 235
Cdd:MTH00174 179 GVRLAANISSGHLLFSIIASFAWKMINTGILIGSfVPFAILIfvTILEMAVAIIQAYVFTLLTIVYLRDTV 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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