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Conserved domains on  [gi|489818194|ref|WP_003722009|]
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DedA family protein [Listeria monocytogenes]

Protein Classification

DedA family protein( domain architecture ID 11426582)

DedA family membrane protein is an inner membrane protein that may play an important role in membrane homeostasis

Gene Ontology:  GO:0016020
PubMed:  23086209|33771928

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
11-208 7.05e-61

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440351  Cd Length: 201  Bit Score: 188.52  E-value: 7.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  11 DFTMWLVDSLGHWGIFLGMLIESVCIPLPSEVIMLFGGFMAEAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLK 90
Cdd:COG0586    4 DFLDALIAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  91 FGKYiFLNVKHLDKAELWFGRYGARAVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGSNW 170
Cdd:COG0586   84 LGRR-FLKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENL 162
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489818194 171 SVVEKYTRPISYLMLALVIAIVVYLAYKVWNKRARNAK 208
Cdd:COG0586  163 PLVLEYLGRYGLVVLAIVVVLLLPLVLRLLRKRRRARA 200
 
Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
11-208 7.05e-61

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440351  Cd Length: 201  Bit Score: 188.52  E-value: 7.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  11 DFTMWLVDSLGHWGIFLGMLIESVCIPLPSEVIMLFGGFMAEAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLK 90
Cdd:COG0586    4 DFLDALIAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  91 FGKYiFLNVKHLDKAELWFGRYGARAVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGSNW 170
Cdd:COG0586   84 LGRR-FLKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENL 162
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489818194 171 SVVEKYTRPISYLMLALVIAIVVYLAYKVWNKRARNAK 208
Cdd:COG0586  163 PLVLEYLGRYGLVVLAIVVVLLLPLVLRLLRKRRRARA 200
SNARE_assoc pfam09335
SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast ...
38-165 3.10e-21

SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast member of this family localizes with the t-SNARE Tlg2.


Pssm-ID: 430535  Cd Length: 120  Bit Score: 84.63  E-value: 3.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194   38 LPSEVIMLFGGFMAeagklNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLKFgkyiFLNVKHLDKAELWFGRYGARAV 117
Cdd:pfam09335   1 IPGEVLLIAAGFLF-----GPWLGFLLALLGALLGALLAYLLGRYFGRRSIVRR----LLKEKRFKKVERLLEKYGFLAL 71
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 489818194  118 FFGRVLPVI-RTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYS 165
Cdd:pfam09335  72 LLLRLIPGVpRDLVNYAAGATRVPFRRFFLATLLGSIPWALVYVYLGYL 120
PRK10847 PRK10847
DedA family protein;
38-208 1.27e-10

DedA family protein;


Pssm-ID: 182775  Cd Length: 219  Bit Score: 58.58  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  38 LPSEVIMLFGGFMA--EAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLKFGKYIFLNvKHLDKAELWFGRYGAR 115
Cdd:PRK10847  49 LPGDSLLFVAGALAslPTNDLNVHMMVALMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRR-SYLDKTHQFYEKHGGK 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194 116 AVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGsNWSVVEKytrPISYLMLALVIAIVVYL 195
Cdd:PRK10847 128 TIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFG-TLPFVQD---NLKLLIVGIIVVSILPG 203
                        170
                 ....*....|...
gi 489818194 196 AYKVWNKRARNAK 208
Cdd:PRK10847 204 VIEIWRHKRAAAR 216
 
Name Accession Description Interval E-value
DedA COG0586
Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane ...
11-208 7.05e-61

Membrane integrity protein DedA, putative transporter, DedA/Tvp38 family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440351  Cd Length: 201  Bit Score: 188.52  E-value: 7.05e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  11 DFTMWLVDSLGHWGIFLGMLIESVCIPLPSEVIMLFGGFMAEAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLK 90
Cdd:COG0586    4 DFLDALIAQWGYLGLFLLVFLESVGPPLPGESLLFLAGALAAQGELSLWLVLLAATLGALLGDLIGYWIGRRLGRRLLRR 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  91 FGKYiFLNVKHLDKAELWFGRYGARAVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGSNW 170
Cdd:COG0586   84 LGRR-FLKPERLDRAEAFFERHGGKAVFLGRFIPGVRTLVPLVAGAARMPYRRFLLYNALGALLWVGLLVLLGYLLGENL 162
                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489818194 171 SVVEKYTRPISYLMLALVIAIVVYLAYKVWNKRARNAK 208
Cdd:COG0586  163 PLVLEYLGRYGLVVLAIVVVLLLPLVLRLLRKRRRARA 200
SNARE_assoc pfam09335
SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast ...
38-165 3.10e-21

SNARE associated Golgi protein; This is a family of SNARE associated Golgi proteins. The yeast member of this family localizes with the t-SNARE Tlg2.


Pssm-ID: 430535  Cd Length: 120  Bit Score: 84.63  E-value: 3.10e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194   38 LPSEVIMLFGGFMAeagklNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLKFgkyiFLNVKHLDKAELWFGRYGARAV 117
Cdd:pfam09335   1 IPGEVLLIAAGFLF-----GPWLGFLLALLGALLGALLAYLLGRYFGRRSIVRR----LLKEKRFKKVERLLEKYGFLAL 71
                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 489818194  118 FFGRVLPVI-RTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYS 165
Cdd:pfam09335  72 LLLRLIPGVpRDLVNYAAGATRVPFRRFFLATLLGSIPWALVYVYLGYL 120
YqaA COG1238
Uncharacterized membrane protein YqaA, VTT domain [Function unknown];
5-167 4.05e-21

Uncharacterized membrane protein YqaA, VTT domain [Function unknown];


Pssm-ID: 440851  Cd Length: 162  Bit Score: 85.64  E-value: 4.05e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194   5 LIQSLQDFTMWLVDSLGHWGIFLGMLIESVCIPLPSEVIMLFggfMAEAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGG 84
Cdd:COG1238    1 MLRRLYDWTRWALHRYGLWGLFLVSFLEATFLPIPSEVLLVP---MLLAGPERAWLLALVATLGSVLGGLVGYAIGRFLF 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  85 RALVLKFGKYIFLNvKHLDKAELWFGRYGARAVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGY 164
Cdd:COG1238   78 EAVGRPLLERYGKE-EKLERAQAWFRRYGFWALLLAGWTPIPGDVLTIAAGVLRLPLWPFLLASLIGRGARFFLVALLLL 156

                 ...
gi 489818194 165 SLG 167
Cdd:COG1238  157 WFG 159
TVP38 COG0398
Uncharacterized membrane protein YdjX, related to fungal oxalate transporter, TVP38/TMEM64 ...
16-205 1.16e-16

Uncharacterized membrane protein YdjX, related to fungal oxalate transporter, TVP38/TMEM64 family [Function unknown];


Pssm-ID: 440167 [Multi-domain]  Cd Length: 209  Bit Score: 74.89  E-value: 1.16e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  16 LVDSLGHWGIFLGMLIESVC--IPLPSEVIMLFGGFMaeagkLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLKFgk 93
Cdd:COG0398   31 WIESLGPLAPLVFILLYALQtlLPLPGTVLTLAAGAL-----FGPWLGTLLSLIGATLGALLAFLLARYLGRDFVERL-- 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  94 yifLNVKHLDKAELWFGRYGARAVFFGRVLPVI-RTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGSNWSV 172
Cdd:COG0398  104 ---LGKPRLKRLDRLLERNGFLAVFLLRLIPVFpFDLVNYAAGLTGVRLRTFLLATLLGMLPGTLVYVYLGAGLASLNSL 180
                        170       180       190
                 ....*....|....*....|....*....|...
gi 489818194 173 vekytrPISYLMLALVIAIVVYLAYKVWNKRAR 205
Cdd:COG0398  181 ------GLLLALALLALLALLGLLLRRLRRRLK 207
PRK10847 PRK10847
DedA family protein;
38-208 1.27e-10

DedA family protein;


Pssm-ID: 182775  Cd Length: 219  Bit Score: 58.58  E-value: 1.27e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194  38 LPSEVIMLFGGFMA--EAGKLNFWLVVFAGISGNLVGSLIAYYIGKFGGRALVLKFGKYIFLNvKHLDKAELWFGRYGAR 115
Cdd:PRK10847  49 LPGDSLLFVAGALAslPTNDLNVHMMVALMLIAAIVGDAVNYTIGRLFGEKLFSNPNSKIFRR-SYLDKTHQFYEKHGGK 127
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489818194 116 AVFFGRVLPVIRTFISLPAGIAKMNVWKFIIYTILGCIPWNIFLTWLGYSLGsNWSVVEKytrPISYLMLALVIAIVVYL 195
Cdd:PRK10847 128 TIILARFVPIVRTFAPFVAGMGHMSYRHFAAYNVIGALLWVLLFTYAGYFFG-TLPFVQD---NLKLLIVGIIVVSILPG 203
                        170
                 ....*....|...
gi 489818194 196 AYKVWNKRARNAK 208
Cdd:PRK10847 204 VIEIWRHKRAAAR 216
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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