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Conserved domains on  [gi|489819402|ref|WP_003723213|]
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MULTISPECIES: Sec-independent protein translocase subunit TatA [Listeria]

Protein Classification

twin-arginine translocase TatA/TatE family subunit( domain architecture ID 10014915)

twin-arginine translocase TatA/TatE family subunit similar to Sec-independent protein translocase protein TatA, which may form the protein-conducting channel of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatA PRK14861
twin arginine translocase protein A; Provisional
 2-56 2.33e-24

twin arginine translocase protein A; Provisional


:

Pssm-ID: 237837  Cd Length: 61  Bit Score: 85.41  E-value: 2.33e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKED 56
Cdd:PRK14861  5 IGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATKELTDDDFQEKKKKE 59
 
Name Accession Description Interval E-value
tatA PRK14861
twin arginine translocase protein A; Provisional
 2-56 2.33e-24

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 85.41  E-value: 2.33e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKED 56
Cdd:PRK14861  5 IGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATKELTDDDFQEKKKKE 59
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 2-54 6.56e-18

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 68.87  E-value: 6.56e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKK 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-58 3.45e-15

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 62.26  E-value: 3.45e-15
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819402  1 MIGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKEDPR 58
Cdd:COG1826   3 GIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELR 60
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 1-47 1.24e-12

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 55.31  E-value: 1.24e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 489819402   1 MIGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDD 47
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
 
Name Accession Description Interval E-value
tatA PRK14861
twin arginine translocase protein A; Provisional
 2-56 2.33e-24

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 85.41  E-value: 2.33e-24
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKED 56
Cdd:PRK14861  5 IGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKATKELTDDDFQEKKKKE 59
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 2-54 6.56e-18

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 68.87  E-value: 6.56e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKK 54
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-58 3.45e-15

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 62.26  E-value: 3.45e-15
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819402  1 MIGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKEDPR 58
Cdd:COG1826   3 GIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELR 60
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 1-47 1.24e-12

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 55.31  E-value: 1.24e-12
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 489819402   1 MIGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDD 47
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEEDE 47
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
2-42 2.24e-11

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 53.19  E-value: 2.24e-11
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATK 42
Cdd:PRK14857  6 IGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASK 46
tatA PRK00575
Sec-independent protein translocase subunit TatA;
2-59 5.33e-10

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 49.74  E-value: 5.33e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKEDPRP 59
Cdd:PRK00575  4 LSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKSEVKEMQSDNKAEASAAAAQA 61
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-58 5.57e-10

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 48.96  E-value: 5.57e-10
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489819402  1 MIGPGSIALIV--GAALVIFGPKKLPELGRAAGDTLREFKNATKG--MMDDSKEETKKEDPR 58
Cdd:PRK14860  1 MFGFGMPELIVilVIALVVFGPAKLPQLGQALGGAIRNFKKASNEedVVTINNEKGKEDQAR 62
PRK01371 PRK01371
Sec-independent protein translocase protein TatB;
2-51 1.77e-09

Sec-independent protein translocase protein TatB;


Pssm-ID: 179287 [Multi-domain]  Cd Length: 137  Bit Score: 49.32  E-value: 1.77e-09
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEE 51
Cdd:PRK01371   4 IGPGELVVLVVLAVLVFGPDKLPKAARDAGRTLRQLREMANNARNDLRSE 53
tatA PRK00191
twin arginine translocase protein A; Provisional
 2-58 2.47e-09

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 48.03  E-value: 2.47e-09
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMM-DDSKEETKKEDPR 58
Cdd:PRK00191  3 LGPWEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFKSEVKEMSkDDQTPEQQQQQPQ 60
tatA PRK14858
twin arginine translocase protein A; Provisional
 2-58 1.09e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 41.77  E-value: 1.09e-06
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKEDPR 58
Cdd:PRK14858   4 IGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKATDDFKQSMQEESRTAEEK 60
tatA PRK14859
twin arginine translocase protein A; Provisional
 2-56 5.17e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 38.94  E-value: 5.17e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*
gi 489819402  2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREFKNATKGMMDDSKEETKKED 56
Cdd:PRK14859  4 IGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEIEIKPTKKED 58
tatB TIGR01410
twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a ...
 2-55 2.21e-05

twin arginine-targeting protein translocase TatB; This model represents the TatB protein of a Sec-independent system for transporting folded proteins, often with a bound redox cofactor, across the bacterial inner membrane. TatC is the multiple membrane spanning component. TatB, like the related TatA/E proteins, appears to span the membrane one time. The tat system recognizes proteins with an elongated signal sequence containing a conserved R-R in a motif approximated by RRxFLK N-terminal to the transmembrane helix. TIGRFAMs model TIGR01409 describes this twin-Arg signal sequence. A similar system, termed Delta-pH-dependent transport, operates on chloroplast-encoded proteins. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 130477 [Multi-domain]  Cd Length: 80  Bit Score: 37.68  E-value: 2.21e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLRefknATKGMMDDSKEETKKE 55
Cdd:TIGR01410  3 IGFSELLLIAVVALVVLGPERLPVAIRTVGGFVR----ALRGMASDVKNELDEE 52
PRK04654 PRK04654
sec-independent translocase; Provisional
 2-55 4.54e-05

sec-independent translocase; Provisional


Pssm-ID: 135173 [Multi-domain]  Cd Length: 214  Bit Score: 38.64  E-value: 4.54e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....
gi 489819402   2 IGPGSIALIVGAALVIFGPKKLPELGRAAGDTLREfknaTKGMMDDSKEETKKE 55
Cdd:PRK04654   4 IGVGELTLIAVVALVVLGPERLPKAARFAGLWVRR----ARMQWDSVKQELERE 53
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
7-59 7.92e-03

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 31.39  E-value: 7.92e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|...
gi 489819402  7 IALIVGAALViFGPKKLPELGRAAGDTLREFKnatKGMMDDSKEETKKEDPRP 59
Cdd:PRK00442 10 IVILVVVVLV-FGTKKLKNLGSDVGESIKGFR---KAMNEDEKEDKPAEQPAP 58
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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