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Conserved domains on  [gi|489819498|ref|WP_003723309|]
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universal stress protein [Listeria monocytogenes]

Protein Classification

universal stress protein( domain architecture ID 10084616)

universal stress protein (USP) enhances the rate of cell survival during prolonged exposure to stress agents

CATH:  3.40.50.620
Gene Ontology:  GO:0005524|GO:0050896
PubMed:  23745136|12012333|36902153
SCOP:  4003850

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 7-143 1.17e-40

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


:

Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 132.86  E-value: 1.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGVtKVES 86
Cdd:cd00293    1 KILVAVDGSEESERALEWALELAKRPGAELTLLHVVDPPPSSSLSGGLEELADELKEEAEELLEEAKKLAEEAGV-EVET 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489819498  87 YIEYGSPKTAITKEaAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVV 143
Cdd:cd00293   80 IVVEGDPAEAILEE-AKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAPCPVLVV 135
 
Name Accession Description Interval E-value
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 7-143 1.17e-40

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 132.86  E-value: 1.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGVtKVES 86
Cdd:cd00293    1 KILVAVDGSEESERALEWALELAKRPGAELTLLHVVDPPPSSSLSGGLEELADELKEEAEELLEEAKKLAEEAGV-EVET 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489819498  87 YIEYGSPKTAITKEaAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVV 143
Cdd:cd00293   80 IVVEGDPAEAILEE-AKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAPCPVLVV 135
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
5-143 7.61e-40

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 130.81  E-value: 7.61e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   5 YERVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRafSSVANYDTSMADKATEYADELLSGYKEDALKAGVtKV 84
Cdd:COG0589    2 YKRILVPTDGSEEAERALEYAAELAKALGAELHLLHVVDPP--PSAAAGPEELEEELREEAEEALEEAAERLEEAGV-EV 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489819498  85 ESYIEYGSPKTAITkEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVV 143
Cdd:COG0589   79 ETVVREGDPAEAIL-EAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAPCPVLVV 136
Usp pfam00582
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ...
 8-144 1.98e-37

Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.


Pssm-ID: 425765 [Multi-domain]  Cd Length: 137  Bit Score: 124.83  E-value: 1.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498    8 VLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEY-ADELLSGYKEDALKAGVTKVES 86
Cdd:pfam00582   1 ILVAVDGSEESKRALEWAAELAKARGAELILLHVIDPPPSGAASLADESAEEEELELeLAEAEALAAAAAAEAGGVKVEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819498   87 YIEYGSPKTAITkEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:pfam00582  81 VVVVGDPAEEIL-EVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHAPCPVLVVR 137
PRK15005 PRK15005
universal stress protein UspF;
83-144 2.35e-06

universal stress protein UspF;


Pssm-ID: 184967 [Multi-domain]  Cd Length: 144  Bit Score: 44.41  E-value: 2.35e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489819498  83 KVESYIEYGSPKTAITkEAAKAFQADLIMCgATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:PRK15005  85 RVHVHVEEGSPKDRIL-ELAKKIPADMIII-ASHRPDITTYLLGSNAAAVVRHAECSVLVVR 144
 
Name Accession Description Interval E-value
USP-like cd00293
universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a ...
 7-143 1.17e-40

universal stress protein (USP) and similar proteins; The universal stress protein (USP) is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although USP lacks ATP-binding activity.


Pssm-ID: 467483 [Multi-domain]  Cd Length: 135  Bit Score: 132.86  E-value: 1.17e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGVtKVES 86
Cdd:cd00293    1 KILVAVDGSEESERALEWALELAKRPGAELTLLHVVDPPPSSSLSGGLEELADELKEEAEELLEEAKKLAEEAGV-EVET 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 489819498  87 YIEYGSPKTAITKEaAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVV 143
Cdd:cd00293   80 IVVEGDPAEAILEE-AKELGADLIVMGSRGRSGLKRLLLGSVSEYVLRHAPCPVLVV 135
UspA COG0589
Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];
5-143 7.61e-40

Nucleotide-binding universal stress protein, UspA family [Signal transduction mechanisms];


Pssm-ID: 440354  Cd Length: 136  Bit Score: 130.81  E-value: 7.61e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   5 YERVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRafSSVANYDTSMADKATEYADELLSGYKEDALKAGVtKV 84
Cdd:COG0589    2 YKRILVPTDGSEEAERALEYAAELAKALGAELHLLHVVDPP--PSAAAGPEELEEELREEAEEALEEAAERLEEAGV-EV 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 489819498  85 ESYIEYGSPKTAITkEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVV 143
Cdd:COG0589   79 ETVVREGDPAEAIL-EAAEELDADLIVMGSRGRSGLRRLLLGSVAERVLRHAPCPVLVV 136
Usp pfam00582
Universal stress protein family; The universal stress protein UspA is a small cytoplasmic ...
 8-144 1.98e-37

Universal stress protein family; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.


Pssm-ID: 425765 [Multi-domain]  Cd Length: 137  Bit Score: 124.83  E-value: 1.98e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498    8 VLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEY-ADELLSGYKEDALKAGVTKVES 86
Cdd:pfam00582   1 ILVAVDGSEESKRALEWAAELAKARGAELILLHVIDPPPSGAASLADESAEEEELELeLAEAEALAAAAAAEAGGVKVEV 80

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819498   87 YIEYGSPKTAITkEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:pfam00582  81 VVVVGDPAEEIL-EVAEEEDADLIVMGSRGRSGLSRLLLGSVAEYVLRHAPCPVLVVR 137
USP_At3g01520-like cd23659
universal stress protein At3g01520 and similar proteins; This subfamily includes plant and ...
 7-144 1.67e-32

universal stress protein At3g01520 and similar proteins; This subfamily includes plant and fungal proteins of unknown function, including Arabidopsis thaliana At3g01520. A. thaliana contains 44 USP domain-containing proteins; the USP domain is found either in a small protein with unknown physiological function or as an N-terminal portion of a multi-domain protein, usually a protein kinase. The gene At3g01520 of Arabidopsis thaliana encodes a 175-residue universal stress protein (USP)-like protein which is widely found in the genomes of bacteria, as well as fungi, protozoa, and plants. The bound AMP and conservation of residues in the ATP-binding loop suggest that the protein At3g01520 belongs to the ATP-binding USP subfamily. Universal stress proteins (USPs) are small cytoplasmic bacterial proteins whose expression is enhanced when the cell is exposed to stress agents. USP enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467505  Cd Length: 143  Bit Score: 112.33  E-value: 1.67e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVID-----TRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGV 81
Cdd:cd23659    2 KVLIAVDGSEESEYALEWALENLHRPGDEVVLLHVIEppslpAASLGSGSEEWEALEEEAREKAEKLLEKYEKKLKEEKG 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489819498  82 TKVESYIEYGSPKTAITKeAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:cd23659   82 IKVKVEVVAGDPGEVICK-AAEELKADLIVMGSRGLGALKRTLLGSVSDYVVHHSPCPVLVVR 143
USP-A-like cd23657
universal stress protein A and similar proteins; The universal stress protein UspA is a small ...
 5-144 7.69e-18

universal stress protein A and similar proteins; The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced several-fold when cellular viability is challenged with heat shock, nutrient starvation, stress agents which arrest cell growth, or DNA-damaging agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, suggesting that it asserts a general "stress endurance" activity. In general, these proteins form dimers and have domains for nucleotide binding activity. The crystal structure of Haemophilus influenzae UspA reveals an asymmetric dimer with a tertiary alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, but unlike MJ0577, it lacks ATP-binding activity.


Pssm-ID: 467504  Cd Length: 138  Bit Score: 74.65  E-value: 7.69e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   5 YERVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTrafssVANYDTSMADKATEYADELLSGYKEDALK-----A 79
Cdd:cd23657    1 YKHILVAVDLSPESQSLVDKAVEIARENDAKLSLIHVDED-----ISEYYTGLIDVDIAALQDLESTMLEEALKnlselA 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489819498  80 GVTKVESYIEYGSPKTAITkEAAKAFQADLIMCGATGLNAVERLliGSVSEYIIRHSPCDVLVVR 144
Cdd:cd23657   76 GYPVDHTFIGYGDLKEEIL-EVAKKHNVDLIVCGHHGDFGLSLL--GSSARAVLNSAPCDVLIVP 137
USP_Rv2623_repeat1 cd23944
universal stress protein Rv2623 and similar proteins, USP repeat 1; Mycobacterium tuberculosis ...
 8-144 3.90e-12

universal stress protein Rv2623 and similar proteins, USP repeat 1; Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth in vitro and in vivo and is required for the entry of the tubercle bacillus into the chronic phase of infection in the host. In addition Rv2623 binds ATP and the growth-regulatory attribute of this USP is dependent on its ATP-binding activity. Rv2623 is thought to function as an ATP-dependent signaling intermediate in a pathway that promotes persistent infection. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although Usp lacks ATP-binding activity.


Pssm-ID: 467509  Cd Length: 140  Bit Score: 59.73  E-value: 3.90e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   8 VLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSV-----ANYDTSMADKATEYADELLSGYKEDALKAGVT 82
Cdd:cd23944    2 IIVGVDGSPASDAAVRWAAREAQLRQIPLTLVHVVPPVVVSWPegprpAEVLDWQQDEARQVIEQARKVAEEASGEGPPV 81

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489819498  83 KVESYIEYGSPKTAITkEAAKafQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:cd23944   82 KVETEIVPGSPVPTLV-EASR--DATMVVVGSRGIGALAGLLLGSVSTSLVRHAHCPVAVIH 140
USP_Rv2623_repeat2 cd23661
universal stress protein Rv2623 and similar proteins, USP repeat 2; Mycobacterium tuberculosis ...
 8-144 8.50e-11

universal stress protein Rv2623 and similar proteins, USP repeat 2; Mycobacterium tuberculosis universal stress protein Rv2623 regulates mycobacterial growth in vitro and in vivo and is required for the entry of the tubercle bacillus into the chronic phase of infection in the host. In addition, Rv2623 binds ATP and the growth-regulatory attribute of this USP is dependent on its ATP-binding activity. Rv2623 is thought to function as an ATP-dependent signaling intermediate in a pathway that promotes persistent infection. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae Usp reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, although Usp lacks ATP-binding activity.


Pssm-ID: 467507 [Multi-domain]  Cd Length: 133  Bit Score: 56.36  E-value: 8.50e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   8 VLVAVDGSKEAERAFQKAIQVANRNDAALGLVHV-IDTRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGVTKVes 86
Cdd:cd23661    2 VVVGVDGSPASELATEIAFDEASRRGVDLVALHAwSDMGPGGFLGIDWRESEQDQERMLAERLAGWQERYPDVHVHKV-- 79

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819498  87 yIEYGSPKTAItKEAAKafQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:cd23661   80 -VVRDRPARVL-LEASE--RAQLVVVGSHGRGGFAGMLLGSVSRAVLHSAPCPVIVVR 133
USP-E_repeat2 cd23660
Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP ...
 7-142 3.83e-08

Universal stress protein E, repeat 2; UspE is a tandem-type USP that consists of two USP domains. The UspE expression levels of Escherichia coli become elevated in response to oxidative stress and DNA damaging agents, including exposure to mitomycin C, cadmium, and hydrogen peroxide. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467506  Cd Length: 148  Bit Score: 49.58  E-value: 3.83e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKE-------AERAFQKAIQVANRNDAALGLVHVIDtrafSSVANYDTSMADKATEYADELLSGYKEDALKA 79
Cdd:cd23660    3 RILVAVDPSNEeeyhedlNLRLIELAYSLAAQLKAELHLVSAWP----VTPENIAIELPEFDPTEYVDAIRGRHLEAMKA 78

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489819498  80 -----GVTKVESYIEYGSPKTAItKEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSPCDVLV 142
Cdd:cd23660   79 lrqkfGIDEEQTHVLEGLPEEVI-PDFAEELDADIVVLGTVARTGLSGALIGNTAEHVLDHLNCDLLA 145
PRK15005 PRK15005
universal stress protein UspF;
83-144 2.35e-06

universal stress protein UspF;


Pssm-ID: 184967 [Multi-domain]  Cd Length: 144  Bit Score: 44.41  E-value: 2.35e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489819498  83 KVESYIEYGSPKTAITkEAAKAFQADLIMCgATGLNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:PRK15005  85 RVHVHVEEGSPKDRIL-ELAKKIPADMIII-ASHRPDITTYLLGSNAAAVVRHAECSVLVVR 144
PRK15118 PRK15118
universal stress protein UspA;
5-113 3.35e-05

universal stress protein UspA;


Pssm-ID: 185073  Cd Length: 144  Bit Score: 41.41  E-value: 3.35e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   5 YERVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFSSVANYDTSMADKATEYADELLSGYKEDALKAGVTKV 84
Cdd:PRK15118   3 YKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYSDLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPIT 82

                         90       100
                 ....*....|....*....|....*....
gi 489819498  85 ESYIEYGSPKTAITkEAAKAFQADLIMCG 113
Cdd:PRK15118  83 ETLSGSGDLGQVLV-DAIKKYDMDLVVCG 110
USP_KdpD-like cd01987
USP domain of the osmosensitive K+ channel histidine kinase family; The KdpDE two component ...
 7-143 2.27e-04

USP domain of the osmosensitive K+ channel histidine kinase family; The KdpDE two component system is widespread in bacteria and archaea; it controls potassium homeostasis and virulence by regulating the transcription of multiple genes, including a kdpFABC operon, which encodes a high-affinity P-type ATPase transporter. The KdpD histidine kinase (HK, EC:2.7.13.3) contain an N-terminal sensory cytoplasmic region (NTR) composed of KdpD' and universal stress protein (USP) domains, a canonical transmembrane domain, and a cytoplasmic C-terminal region with a transmitter GAF domain and an EnvZ-like catalytic HK domain. Proteins containing the USP domain are induced by many environmental stressors such as nutrient starvation, drought, extreme temperatures, high salinity, and the presence of uncouplers, antibiotics, and metals. It enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity.


Pssm-ID: 467491 [Multi-domain]  Cd Length: 124  Bit Score: 38.77  E-value: 2.27e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   7 RVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVIDTRAFssvanydtSMADKATEYADELLSGYKEdaLKAGVTKVES 86
Cdd:cd01987    1 RILVCISSSPTSEKLIRRAARLAERLNGELTAVYVETPEES--------RLDEESQRRLLTNLKLAEE--LGAEVVSVEG 70

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 489819498  87 yieyGSPKTAITkEAAKAFQADLIMCGATGLNAVERLLIGSVSEYIIRHSP-CDVLVV 143
Cdd:cd01987   71 ----DDVAEAIV-EFARERNVTQIVLGQSRRRRWRRLFKGSLVDRLLREAPnIDVHIV 123
PRK15456 PRK15456
universal stress protein UspG; Provisional
 5-144 6.52e-03

universal stress protein UspG; Provisional


Pssm-ID: 185353  Cd Length: 142  Bit Score: 34.92  E-value: 6.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498   5 YERVLVAVDgSKEAERAfQKAIQVAN---RNDAALGLVHVIDTRAFSS-------VANYDTSMADKATEYADELLSGYKE 74
Cdd:PRK15456   2 YKTIIMPVD-VFEMELS-DKAVRHAEflaQDDGVIHLLHVLPGSASLSlhrfaadVRRFEEHLQHEAEERLQTMVSHFTI 79

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819498  75 DAlkagvTKVESYIEYGSPKTAITkEAAKAFQADLIMCGATGlNAVERLLIGSVSEYIIRHSPCDVLVVR 144
Cdd:PRK15456  80 DP-----SRIKQHVRFGSVRDEVN-ELAEELGADVVVIGSRN-PSISTHLLGSNASSVIRHANLPVLVVR 142
PRK09982 PRK09982
universal stress protein UspD; Provisional
 5-43 6.93e-03

universal stress protein UspD; Provisional


Pssm-ID: 137627  Cd Length: 142  Bit Score: 34.98  E-value: 6.93e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 489819498   5 YERVLVAVDGSKEAERAFQKAIQVANRNDAALGLVHVID 43
Cdd:PRK09982   3 YKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDD 41
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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