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Conserved domains on  [gi|489819688|ref|WP_003723498|]
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lmo0171 family class 1 internalin [Listeria monocytogenes]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
InlK_D3 pfam18981
Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, ...
 433-507 4.95e-27

Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, used by the bacteria to invade mammalian cells. This domain has an Ig-like fold.


:

Pssm-ID: 408751 [Multi-domain]  Cd Length: 75  Bit Score: 104.61  E-value: 4.95e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489819688  433 PVIVADKSVSYAPVNAKDEATFLQDIRASASENAQITSDYSEVVNFATPGDYTVTLHAKNEFDLKADPVTVVVHI 507
Cdd:pfam18981   1 PVITADKEITYEKGTTKTEAQFLTDIHATTDDGSTITSDFATVVDLNTPGDYTVTLNATNEDGNKATPVTVTVTV 75
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
53-400 2.50e-20

Leucine-rich repeat (LRR) protein [Transcription];


:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.62  E-value: 2.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  53 MDNSQTAPQKTTASSSEEAATTNSTEEENTPKNNLKSTSENSKTYAELFPDVNLAKIIAKNISGTEDINAEVSEAELQTI 132
Cdd:COG4886   13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 133 TNLV-ATNQNITSLTGIEHLTALENINVNNNELTTI-DSLFNMPTLKSISANNNKITGNFSLVKTLPELHTLEVLGNAIT 210
Cdd:COG4886   93 GDLTnLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 211 ELD--IENQPNLVTLSADELELKKL--TLKNLSQL-------NGLGRIASSISidwgelesvtlmNLPEIESIDISGNYL 279
Cdd:COG4886  173 DLPeeLGNLTNLKELDLSNNQITDLpePLGNLTNLeeldlsgNQLTDLPEPLA------------NLTNLETLDLSNNQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 280 dSDDINLENLPAVKNLDLSSNELTRLPKINDFPLLTTINVRSNKIDRLESSKLVDVPKLATLNADKQAVTLSKTIAAGNF 359
Cdd:COG4886  241 -TDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 489819688 360 TIPNNVENLAGQMVTPKIISNNGTYSDQSIAWASGELSGLS 400
Cdd:COG4886  320 LTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLS 360
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
 684-743 3.16e-15

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


:

Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 70.84  E-value: 3.16e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489819688  684 TIQYMDSENNELAESNTITGEVGETYETLAKEIEGYTLKENPANSSG----VFEETRQTIQYIY 743
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNATGnatgTFTEEPQTVTYVY 64
LapB_rpt_80 super family cl41533
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 482-560 6.17e-09

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


The actual alignment was detected with superfamily member NF033932:

Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 53.54  E-value: 6.17e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489819688 482 GDYTVTLHAKNEFDLKADPVTVVVHINDIQKPqVAVNSNNISFEVGTELTSEVLLAKSGAVVTDLYDEAiKMEVDLSEV 560
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIVDTSAP-VITADKEVSYPKGTTITEAEFLQDIHAKTTDSLSGV-KITSDFATA 77
DUF5011 super family cl47259
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 599-675 1.18e-07

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


The actual alignment was detected with superfamily member pfam16403:

Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 49.47  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  599 IQIN-NPEIIIEKGSELTEGqiidqvGITATDNyDQDLN--IHMDlSKVDTSKPGSYEVTIYTEDSSGNRSeTVTITVKV 675
Cdd:pfam16403   1 ITLNgDNDITIELGTTYEDP------GATATDN-DGDLTdkVKVT-GSVDTSKPGTYTLTYTVTDSDGNSA-TVTRTVTV 71
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 800-831 1.57e-05

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


:

Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.46  E-value: 1.57e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 489819688  800 LPETGDSTNLLFIFMGVLLLAGLTLSKAKRKN 831
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKRKK 33
 
Name Accession Description Interval E-value
InlK_D3 pfam18981
Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, ...
 433-507 4.95e-27

Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, used by the bacteria to invade mammalian cells. This domain has an Ig-like fold.


Pssm-ID: 408751 [Multi-domain]  Cd Length: 75  Bit Score: 104.61  E-value: 4.95e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489819688  433 PVIVADKSVSYAPVNAKDEATFLQDIRASASENAQITSDYSEVVNFATPGDYTVTLHAKNEFDLKADPVTVVVHI 507
Cdd:pfam18981   1 PVITADKEITYEKGTTKTEAQFLTDIHATTDDGSTITSDFATVVDLNTPGDYTVTLNATNEDGNKATPVTVTVTV 75
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
53-400 2.50e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.62  E-value: 2.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  53 MDNSQTAPQKTTASSSEEAATTNSTEEENTPKNNLKSTSENSKTYAELFPDVNLAKIIAKNISGTEDINAEVSEAELQTI 132
Cdd:COG4886   13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 133 TNLV-ATNQNITSLTGIEHLTALENINVNNNELTTI-DSLFNMPTLKSISANNNKITGNFSLVKTLPELHTLEVLGNAIT 210
Cdd:COG4886   93 GDLTnLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 211 ELD--IENQPNLVTLSADELELKKL--TLKNLSQL-------NGLGRIASSISidwgelesvtlmNLPEIESIDISGNYL 279
Cdd:COG4886  173 DLPeeLGNLTNLKELDLSNNQITDLpePLGNLTNLeeldlsgNQLTDLPEPLA------------NLTNLETLDLSNNQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 280 dSDDINLENLPAVKNLDLSSNELTRLPKINDFPLLTTINVRSNKIDRLESSKLVDVPKLATLNADKQAVTLSKTIAAGNF 359
Cdd:COG4886  241 -TDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 489819688 360 TIPNNVENLAGQMVTPKIISNNGTYSDQSIAWASGELSGLS 400
Cdd:COG4886  320 LTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLS 360
LRR_adjacent pfam08191
LRR adjacent; These are small, all beta strand domains, structurally described for the protein ...
 370-428 6.71e-17

LRR adjacent; These are small, all beta strand domains, structurally described for the protein Internalin (InlA) and related proteins InlB, InlE, InlH from the pathogenic bacterium Listeria monocytogenes. Their function appears to be mainly structural: They are fused to the C-terminal end of leucine-rich repeats (LRR), significantly stabilising the LRR, and forming a common rigid entity with the LRR. They are themselves not involved in protein-protein-interactions but help to present the adjacent LRR-domain for this purpose. These domains belong to the family of Ig-like domains in that they consist of two sandwiched beta sheets that follow the classical connectivity of Ig-domains. The beta strands in one of the sheets is, however, much smaller than in most standard Ig-like domains, making it somewhat of an outlier.


Pssm-ID: 369739 [Multi-domain]  Cd Length: 57  Bit Score: 75.10  E-value: 6.71e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489819688  370 GQMVTPKIISNNGTYSDQSIAWASgeLSGLSKVSYTFDEVINSPAIAGKYTGTVNQPIE 428
Cdd:pfam08191   1 GSLVAPSTISNNGTYADPNITWNL--PSFTSEVSYTFNQPITIGKGTATFSGTVTQPLK 57
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
 684-743 3.16e-15

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 70.84  E-value: 3.16e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489819688  684 TIQYMDSENNELAESNTITGEVGETYETLAKEIEGYTLKENPANSSG----VFEETRQTIQYIY 743
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNATGnatgTFTEEPQTVTYVY 64
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 129-310 1.34e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 64.81  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 129 LQTITNLVATNQNITSLTGIEHLTALENINVNNNELTTIDSLFNMPTLKSISANNNKIT--GNFSlvkTLPELHTLEVLG 206
Cdd:cd21340    1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEkiENLE---NLVNLKKLYLGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 207 NAIT------------ELDIENQ--PNLVTLSADELELKKLtLKNLSQLNglgriASSISIDwgELESvtLMNLPEIESI 272
Cdd:cd21340   78 NRISvveglenltnleELHIENQrlPPGEKLTFDPRSLAAL-SNSLRVLN-----ISGNNID--SLEP--LAPLRNLEQL 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 489819688 273 DISGNYLDS-DDIN--LENLPAVKNLDLSSNELTRLPKIND 310
Cdd:cd21340  148 DASNNQISDlEELLdlLSSWPSLRELDLTGNPVCKKPKYRD 188
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 482-560 6.17e-09

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 53.54  E-value: 6.17e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489819688 482 GDYTVTLHAKNEFDLKADPVTVVVHINDIQKPqVAVNSNNISFEVGTELTSEVLLAKSGAVVTDLYDEAiKMEVDLSEV 560
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIVDTSAP-VITADKEVSYPKGTTITEAEFLQDIHAKTTDSLSGV-KITSDFATA 77
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 404-481 1.72e-08

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 52.38  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 404 YTFDEVINSPAIAGKYTGTVNQPIEV--KAVPVIVADKSVSYAPVNAKDEATFLQDIRASASE---NAQITSDYSEVVNF 478
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIvdTSAPVITADKEVSYPKGTTITEAEFLQDIHAKTTDslsGVKITSDFATAVDL 80


                 ...
gi 489819688 479 ATP 481
Cdd:NF033932  81 NKA 83
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 599-675 1.18e-07

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 49.47  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  599 IQIN-NPEIIIEKGSELTEGqiidqvGITATDNyDQDLN--IHMDlSKVDTSKPGSYEVTIYTEDSSGNRSeTVTITVKV 675
Cdd:pfam16403   1 ITLNgDNDITIELGTTYEDP------GATATDN-DGDLTdkVKVT-GSVDTSKPGTYTLTYTVTDSDGNSA-TVTRTVTV 71
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 566-649 2.29e-07

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 48.91  E-value: 2.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 566 GTYEATIIAKSKSGASSDPIKLSVKIVDTEKPIIQiNNPEIIIEKGSELTEGQIIDQVGITATDNYDqDLNIHMDLS-KV 644
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIVDTSAPVIT-ADKEVSYPKGTTITEAEFLQDIHAKTTDSLS-GVKITSDFAtAV 78


                 ....*
gi 489819688 645 DTSKP 649
Cdd:NF033932  79 DLNKA 83
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
130-327 3.82e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.93  E-value: 3.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 130 QTITNLVATNQNITSLTgiEHLTA-LENINVNNNELTTIDSlfNMP-TLKSISANNNKITgnfSLVKTLPE-LHTLEVLG 206
Cdd:PRK15370 199 EQITTLILDNNELKSLP--ENLQGnIKTLYANSNQLTSIPA--TLPdTIQEMELSINRIT---ELPERLPSaLQSLDLFH 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 207 NAITELDiENQPnlvtlsaDELELKKLTLKNLSQLNGlgRIASSISidwgEL--ESVTLMNLPEieSIDISGNYLDSDDI 284
Cdd:PRK15370 272 NKISCLP-ENLP-------EELRYLSVYDNSIRTLPA--HLPSGIT----HLnvQSNSLTALPE--TLPPGLKTLEAGEN 335

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489819688 285 NLENLPA-----VKNLDLSSNELTRLPKINDfPLLTTINVRSNKIDRL 327
Cdd:PRK15370 336 ALTSLPAslppeLQVLDVSKNQITVLPETLP-PTITTLDVSRNALTNL 382
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 800-831 1.57e-05

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.46  E-value: 1.57e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 489819688  800 LPETGDSTNLLFIFMGVLLLAGLTLSKAKRKN 831
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKRKK 33
Gram_pos_anchor pfam00746
LPXTG cell wall anchor motif;
800-832 2.37e-03

LPXTG cell wall anchor motif;


Pssm-ID: 366278 [Multi-domain]  Cd Length: 43  Bit Score: 36.36  E-value: 2.37e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 489819688  800 LPETGDSTNLLFIFMGVL-LLAGLTLSKAKRKNQ 832
Cdd:pfam00746   9 LPKTGENSNIFLTAAGLLaLLGGLLLLVKRRKKE 42
 
Name Accession Description Interval E-value
InlK_D3 pfam18981
Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, ...
 433-507 4.95e-27

Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, used by the bacteria to invade mammalian cells. This domain has an Ig-like fold.


Pssm-ID: 408751 [Multi-domain]  Cd Length: 75  Bit Score: 104.61  E-value: 4.95e-27
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489819688  433 PVIVADKSVSYAPVNAKDEATFLQDIRASASENAQITSDYSEVVNFATPGDYTVTLHAKNEFDLKADPVTVVVHI 507
Cdd:pfam18981   1 PVITADKEITYEKGTTKTEAQFLTDIHATTDDGSTITSDFATVVDLNTPGDYTVTLNATNEDGNKATPVTVTVTV 75
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
53-400 2.50e-20

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 94.62  E-value: 2.50e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  53 MDNSQTAPQKTTASSSEEAATTNSTEEENTPKNNLKSTSENSKTYAELFPDVNLAKIIAKNISGTEDINAEVSEAELQTI 132
Cdd:COG4886   13 LLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 133 TNLV-ATNQNITSLTGIEHLTALENINVNNNELTTI-DSLFNMPTLKSISANNNKITGNFSLVKTLPELHTLEVLGNAIT 210
Cdd:COG4886   93 GDLTnLTELDLSGNEELSNLTNLESLDLSGNQLTDLpEELANLTNLKELDLSNNQLTDLPEPLGNLTNLKSLDLSNNQLT 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 211 ELD--IENQPNLVTLSADELELKKL--TLKNLSQL-------NGLGRIASSISidwgelesvtlmNLPEIESIDISGNYL 279
Cdd:COG4886  173 DLPeeLGNLTNLKELDLSNNQITDLpePLGNLTNLeeldlsgNQLTDLPEPLA------------NLTNLETLDLSNNQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 280 dSDDINLENLPAVKNLDLSSNELTRLPKINDFPLLTTINVRSNKIDRLESSKLVDVPKLATLNADKQAVTLSKTIAAGNF 359
Cdd:COG4886  241 -TDLPELGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLL 319

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|.
gi 489819688 360 TIPNNVENLAGQMVTPKIISNNGTYSDQSIAWASGELSGLS 400
Cdd:COG4886  320 LTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLS 360
LRR_adjacent pfam08191
LRR adjacent; These are small, all beta strand domains, structurally described for the protein ...
 370-428 6.71e-17

LRR adjacent; These are small, all beta strand domains, structurally described for the protein Internalin (InlA) and related proteins InlB, InlE, InlH from the pathogenic bacterium Listeria monocytogenes. Their function appears to be mainly structural: They are fused to the C-terminal end of leucine-rich repeats (LRR), significantly stabilising the LRR, and forming a common rigid entity with the LRR. They are themselves not involved in protein-protein-interactions but help to present the adjacent LRR-domain for this purpose. These domains belong to the family of Ig-like domains in that they consist of two sandwiched beta sheets that follow the classical connectivity of Ig-domains. The beta strands in one of the sheets is, however, much smaller than in most standard Ig-like domains, making it somewhat of an outlier.


Pssm-ID: 369739 [Multi-domain]  Cd Length: 57  Bit Score: 75.10  E-value: 6.71e-17
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*....
gi 489819688  370 GQMVTPKIISNNGTYSDQSIAWASgeLSGLSKVSYTFDEVINSPAIAGKYTGTVNQPIE 428
Cdd:pfam08191   1 GSLVAPSTISNNGTYADPNITWNL--PSFTSEVSYTFNQPITIGKGTATFSGTVTQPLK 57
MucBP pfam06458
MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial ...
 684-743 3.16e-15

MucBP domain; The MucBP (MUCin-Binding Protein) domain is found in a wide variety of bacterial proteins, in several repeats. The domain is found in bacterial peptidoglycan bound proteins and is often found in conjunction with pfam00746 and pfam00560.


Pssm-ID: 461917 [Multi-domain]  Cd Length: 65  Bit Score: 70.84  E-value: 3.16e-15
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489819688  684 TIQYMDSENNELAESNTITGEVGETYETLAKEIEGYTLKENPANSSG----VFEETRQTIQYIY 743
Cdd:pfam06458   1 TVNYVDEDGNELADSTTLTGKIGDTYTTEAKEIPGYTLVETPGNATGnatgTFTEEPQTVTYVY 64
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
84-349 4.38e-13

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 72.27  E-value: 4.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  84 KNNLKSTSENSKTYAELFPDVNLAKIIAKNISGTEDINAEVSEAELQTITNLVATNQNITSLTGIEHLTALENINVNNNE 163
Cdd:COG4886    6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLL 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 164 LTTIDSLFNMPTLKSISANNNKITGNfslvktLPELHTLEVLGNAITEL--DIENQPNLVTLSADELELKKL--TLKNLS 239
Cdd:COG4886   86 LLGLTDLGDLTNLTELDLSGNEELSN------LTNLESLDLSGNQLTDLpeELANLTNLKELDLSNNQLTDLpePLGNLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 240 QL-------NGLGRIASSISiDWGELE------------SVTLMNLPEIESIDISGNYLDSDDINLENLPAVKNLDLSSN 300
Cdd:COG4886  160 NLksldlsnNQLTDLPEELG-NLTNLKeldlsnnqitdlPEPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNN 238

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 489819688 301 ELTRLPKINDFPLLTTINVRSNKIDRLesSKLVDVPKLATLNADKQAVT 349
Cdd:COG4886  239 QLTDLPELGNLTNLEELDLSNNQLTDL--PPLANLTNLKTLDLSNNQLT 285
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 129-310 1.34e-11

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 64.81  E-value: 1.34e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 129 LQTITNLVATNQNITSLTGIEHLTALENINVNNNELTTIDSLFNMPTLKSISANNNKIT--GNFSlvkTLPELHTLEVLG 206
Cdd:cd21340    1 LKRITHLYLNDKNITKIDNLSLCKNLKVLYLYDNKITKIENLEFLTNLTHLYLQNNQIEkiENLE---NLVNLKKLYLGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 207 NAIT------------ELDIENQ--PNLVTLSADELELKKLtLKNLSQLNglgriASSISIDwgELESvtLMNLPEIESI 272
Cdd:cd21340   78 NRISvveglenltnleELHIENQrlPPGEKLTFDPRSLAAL-SNSLRVLN-----ISGNNID--SLEP--LAPLRNLEQL 147

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 489819688 273 DISGNYLDS-DDIN--LENLPAVKNLDLSSNELTRLPKIND 310
Cdd:cd21340  148 DASNNQISDlEELLdlLSSWPSLRELDLTGNPVCKKPKYRD 188
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
127-338 1.10e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.49  E-value: 1.10e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 127 AELQTITNLVATNQNITSL-TGIEHLTALENINVNNNELTTIDSLFNMPTLKSISANNNKITgNFSLVKTLPELHTLEVL 205
Cdd:COG4886  202 GNLTNLEELDLSGNQLTDLpEPLANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNNQLT-DLPPLANLTNLKTLDLS 280

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 206 GNAITELDIENQPNLVTLSADELELKKLTLKNLSQLNGLGRIASSISIDWGELESVTLMNLPEIESIDISGNYLDSDDIN 285
Cdd:COG4886  281 NNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLS 360

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489819688 286 LENLPAVKNLDLSSNELTRLPKINDFPLLTTINVRSNKIDRLESSKLVDVPKL 338
Cdd:COG4886  361 LLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAVNT 413
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 482-560 6.17e-09

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 53.54  E-value: 6.17e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489819688 482 GDYTVTLHAKNEFDLKADPVTVVVHINDIQKPqVAVNSNNISFEVGTELTSEVLLAKSGAVVTDLYDEAiKMEVDLSEV 560
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIVDTSAP-VITADKEVSYPKGTTITEAEFLQDIHAKTTDSLSGV-KITSDFATA 77
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 404-481 1.72e-08

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 52.38  E-value: 1.72e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 404 YTFDEVINSPAIAGKYTGTVNQPIEV--KAVPVIVADKSVSYAPVNAKDEATFLQDIRASASE---NAQITSDYSEVVNF 478
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIvdTSAPVITADKEVSYPKGTTITEAEFLQDIHAKTTDslsGVKITSDFATAVDL 80


                 ...
gi 489819688 479 ATP 481
Cdd:NF033932  81 NKA 83
DUF5011 pfam16403
Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like ...
 599-675 1.18e-07

Domain of unknown function (DUF5011); This entry represents a bacterial immunoglobulin-like domain.


Pssm-ID: 435320 [Multi-domain]  Cd Length: 71  Bit Score: 49.47  E-value: 1.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  599 IQIN-NPEIIIEKGSELTEGqiidqvGITATDNyDQDLN--IHMDlSKVDTSKPGSYEVTIYTEDSSGNRSeTVTITVKV 675
Cdd:pfam16403   1 ITLNgDNDITIELGTTYEDP------GATATDN-DGDLTdkVKVT-GSVDTSKPGTYTLTYTVTDSDGNSA-TVTRTVTV 71
LapB_rpt_80 NF033932
LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in ...
 566-649 2.29e-07

LapB C-terminal region repeat; This model describes a tandem repeat about 80 amino acids in length per repeat, found in at least 12 different surface-exposed proteins of the pathogen Listeria monocytogenes, and in particular found 10 times in tandem in the surface protein LapB, for which the repeat is named.


Pssm-ID: 468252 [Multi-domain]  Cd Length: 83  Bit Score: 48.91  E-value: 2.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 566 GTYEATIIAKSKSGASSDPIKLSVKIVDTEKPIIQiNNPEIIIEKGSELTEGQIIDQVGITATDNYDqDLNIHMDLS-KV 644
Cdd:NF033932   1 GDYTVTLNATNEDGNKATPVKVTVTIVDTSAPVIT-ADKEVSYPKGTTITEAEFLQDIHAKTTDSLS-GVKITSDFAtAV 78


                 ....*
gi 489819688 645 DTSKP 649
Cdd:NF033932  79 DLNKA 83
InlK_D3 pfam18981
Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, ...
 597-675 3.48e-07

Internalin K domain (D3/D4); This domain is found at the elbow of internalin surface proteins, used by the bacteria to invade mammalian cells. This domain has an Ig-like fold.


Pssm-ID: 408751 [Multi-domain]  Cd Length: 75  Bit Score: 48.38  E-value: 3.48e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  597 PIIQiNNPEIIIEKGSELTEGQIIDQVGITATDNydqdLNIHMDL-SKVDTSKPGSYEVTIYTEDSSGNRSETVTITVKV 675
Cdd:pfam18981   1 PVIT-ADKEITYEKGTTKTEAQFLTDIHATTDDG----STITSDFaTVVDLNTPGDYTVTLNATNEDGNKATPVTVTVTV 75
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
130-327 3.82e-07

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 53.93  E-value: 3.82e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 130 QTITNLVATNQNITSLTgiEHLTA-LENINVNNNELTTIDSlfNMP-TLKSISANNNKITgnfSLVKTLPE-LHTLEVLG 206
Cdd:PRK15370 199 EQITTLILDNNELKSLP--ENLQGnIKTLYANSNQLTSIPA--TLPdTIQEMELSINRIT---ELPERLPSaLQSLDLFH 271

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 207 NAITELDiENQPnlvtlsaDELELKKLTLKNLSQLNGlgRIASSISidwgEL--ESVTLMNLPEieSIDISGNYLDSDDI 284
Cdd:PRK15370 272 NKISCLP-ENLP-------EELRYLSVYDNSIRTLPA--HLPSGIT----HLnvQSNSLTALPE--TLPPGLKTLEAGEN 335

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489819688 285 NLENLPA-----VKNLDLSSNELTRLPKINDfPLLTTINVRSNKIDRL 327
Cdd:PRK15370 336 ALTSLPAslppeLQVLDVSKNQITVLPETLP-PTITTLDVSRNALTNL 382
PRK15370 PRK15370
type III secretion system effector E3 ubiquitin transferase SlrP;
84-330 2.52e-06

type III secretion system effector E3 ubiquitin transferase SlrP;


Pssm-ID: 185268 [Multi-domain]  Cd Length: 754  Bit Score: 51.24  E-value: 2.52e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  84 KNNLKSTSENSKtyaelfpdvnlAKIiaKNISGTEDINAEVSEAELQTITNLVATNQNITSLTgiEHL-TALENINVNNN 162
Cdd:PRK15370 208 NNELKSLPENLQ-----------GNI--KTLYANSNQLTSIPATLPDTIQEMELSINRITELP--ERLpSALQSLDLFHN 272

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 163 ELTTIDSlfNMPT-LKSISANNNKITgnfSLVKTLPE-LHTLEVLGNAITELDIENQPNLVTLSADElelkkltlknlsq 240
Cdd:PRK15370 273 KISCLPE--NLPEeLRYLSVYDNSIR---TLPAHLPSgITHLNVQSNSLTALPETLPPGLKTLEAGE------------- 334

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 241 lNGLGRIASSISidwgelesvtlmnlPEIESIDISGNYLDsddINLENLP-AVKNLDLSSNELTRLPKiNDFPLLTTINV 319
Cdd:PRK15370 335 -NALTSLPASLP--------------PELQVLDVSKNQIT---VLPETLPpTITTLDVSRNALTNLPE-NLPAALQIMQA 395

                        250
                 ....*....|.
gi 489819688 320 RSNKIDRLESS 330
Cdd:PRK15370 396 SRNNLVRLPES 406
LPXTG_anchor TIGR01167
LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region ...
 800-831 1.57e-05

LPXTG-motif cell wall anchor domain; This model describes the LPXTG motif-containing region found at the C-terminus of many surface proteins of Streptococcus and Streptomyces species. Cleavage between the Thr and Gly by sortase or a related enzyme leads to covalent anchoring at the new C-terminal Thr to the cell wall. Hits that do not lie at the C-terminus or are not found in Gram-positive bacteria are probably false-positive. A common feature of this proteins containing this domain appears to be a high proportion of charged and zwitterionic residues immediatedly upstream of the LPXTG motif. This model differs from other descriptions of the LPXTG region by including a portion of that upstream charged region. [Cell envelope, Other]


Pssm-ID: 273478 [Multi-domain]  Cd Length: 34  Bit Score: 42.46  E-value: 1.57e-05
                          10        20        30
                  ....*....|....*....|....*....|..
gi 489819688  800 LPETGDSTNLLFIFMGVLLLAGLTLSKAKRKN 831
Cdd:TIGR01167   2 LPKTGESGNSLLLLLGLLLLGLGGLLLRKRKK 33
LRR_RI cd00116
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ...
 150-324 1.66e-05

Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).


Pssm-ID: 238064 [Multi-domain]  Cd Length: 319  Bit Score: 47.74  E-value: 1.66e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 150 HLTALENINVNNNEL------TTIDSLF-NMPTLKSISANNNKITGN--FSLVKTLPE---LHTLEVLGNAITELDIenq 217
Cdd:cd00116  106 RSSSLQELKLNNNGLgdrglrLLAKGLKdLPPALEKLVLGRNRLEGAscEALAKALRAnrdLKELNLANNGIGDAGI--- 182

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 218 PNLVTLSADELELKKLTLKNlsqlNGLGRIASSISidwgeleSVTLMNLPEIESIDISGNYLDS------DDINLENLPA 291
Cdd:cd00116  183 RALAEGLKANCNLEVLDLNN----NGLTDEGASAL-------AETLASLKSLEVLNLGDNNLTDagaaalASALLSPNIS 251

                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 489819688 292 VKNLDLSSNELTRLPK------INDFPLLTTINVRSNKI 324
Cdd:cd00116  252 LLTLSLSCNDITDDGAkdlaevLAEKESLLELDLRGNKF 290
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
172-342 3.42e-05

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 47.24  E-value: 3.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 172 NMPTLKSISANNNKITGNFSLVKTLPELHTLEVLGNAITELDIENQPNLVTLSADELELKKLTLKNLSQLNGLGRIASSI 251
Cdd:COG4886    1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688 252 SIDWGELESVTLMNLPEIESIDISGNyldsddINLENLPAVKNLDLSSNELTRLPK-INDFPLLTTINVRSNKIDRLESS 330
Cdd:COG4886   81 LLSLLLLGLTDLGDLTNLTELDLSGN------EELSNLTNLESLDLSGNQLTDLPEeLANLTNLKELDLSNNQLTDLPEP 154

                        170
                 ....*....|..
gi 489819688 331 kLVDVPKLATLN 342
Cdd:COG4886  155 -LGNLTNLKSLD 165
LRR_8 pfam13855
Leucine rich repeat;
267-324 1.45e-04

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 40.59  E-value: 1.45e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489819688  267 PEIESIDISGNYLDS-DDINLENLPAVKNLDLSSNELTRLPK--INDFPLLTTINVRSNKI 324
Cdd:pfam13855   1 PNLRSLDLSNNRLTSlDDGAFKGLSNLKVLDLSNNLLTTLSPgaFSGLPSLRYLDLSGNRL 61
LRR_9 pfam14580
Leucine-rich repeat;
131-224 1.64e-04

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 43.21  E-value: 1.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489819688  131 TITNLVATnqnitsltgiehLTALENINVNNNELTTIDSLFNMPTLKSISANNNKITG-NFSLVKTLPELHTLEVLGNAI 209
Cdd:pfam14580  33 IIENLGAT------------LDQFDTIDFSDNEIRKLDGFPLLRRLKTLLLNNNRICRiGEGLGEALPNLTELILTNNNL 100

                          90
                  ....*....|....*....
gi 489819688  210 TEL-DIE---NQPNLVTLS 224
Cdd:pfam14580 101 QELgDLDplaSLKKLTFLS 119
Gram_pos_anchor pfam00746
LPXTG cell wall anchor motif;
800-832 2.37e-03

LPXTG cell wall anchor motif;


Pssm-ID: 366278 [Multi-domain]  Cd Length: 43  Bit Score: 36.36  E-value: 2.37e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 489819688  800 LPETGDSTNLLFIFMGVL-LLAGLTLSKAKRKNQ 832
Cdd:pfam00746   9 LPKTGENSNIFLTAAGLLaLLGGLLLLVKRRKKE 42
LRR_8 pfam13855
Leucine rich repeat;
290-344 6.05e-03

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 35.96  E-value: 6.05e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 489819688  290 PAVKNLDLSSNELTRLPK--INDFPLLTTINVRSNKIDRLESSKLVDVPKLATLNAD 344
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDgaFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLS 57
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
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