|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-246 |
1.30e-99 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 290.94 E-value: 1.30e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 4 ENEQEWIG-GRNPVLEVLRSDRDIHKIYVQEGSQKGvLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQ 81
Cdd:COG0566 22 EEEGLFLAeGRHAVEEALKAGREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSGTEtHQGVLAVVRPPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 82 YAELDDLFAAAEAKdemPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNM 161
Cdd:COG0566 101 YADLEDLLAEAGEP---PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 162 VRTMEELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:COG0566 178 ADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYE 257
|
....*
gi 489820279 242 VYRKR 246
Cdd:COG0566 258 AARQR 262
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
7-246 |
7.05e-91 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 268.06 E-value: 7.05e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 7 QEWIGGRNPVLEVLRSDRDIHkiyVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQYAEL 85
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRVF---ILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGnHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 86 DDLFAAAEAKDEmPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTM 165
Cdd:TIGR00186 78 NDLYKTAKSKKQ-PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 166 EELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRK 245
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 489820279 246 R 246
Cdd:TIGR00186 237 R 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
100-242 |
5.22e-86 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 251.92 E-value: 5.22e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTD 179
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 180 AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
7-246 |
6.65e-70 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 214.83 E-value: 6.65e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 7 QEWIGGRNPVLEVLRSD--RDIhKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQY- 82
Cdd:PRK11181 2 SEIIYGIHAVQALLERApeRFI-EVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEGAvHQGIIARVKPGRQl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 83 --AELDDLFAaaeaKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTN 160
Cdd:PRK11181 81 qeNDLPDLLA----SLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 161 MVRTMEELQKRGLWIFGTdaKGSSDYRTMDVDM--PLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLL 238
Cdd:PRK11181 157 LARTMRMLQEKNIWIVGT--AGEADHTLYQSKLtgPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGIC 234
|
....*...
gi 489820279 239 LYEVYRKR 246
Cdd:PRK11181 235 LFEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
99-240 |
1.11e-55 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 175.03 E-value: 1.11e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 99 PFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGL-TQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFG 177
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 178 TDAKGSsDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY 240
Cdd:pfam00588 81 TSLGGK-SLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
10-72 |
1.84e-13 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 63.71 E-value: 1.84e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489820279 10 IGGRNPVLEVLRSDRDIHKIYVQEGSQKgVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQG 72
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAE-RLKELLKLAKERGIKVIEVSKKELDKLSGTAnHQG 63
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| SpoU |
COG0566 |
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA ... |
4-246 |
1.30e-99 |
|
tRNA G18 (ribose-2'-O)-methylase SpoU [Translation, ribosomal structure and biogenesis]; tRNA G18 (ribose-2'-O)-methylase SpoU is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440332 [Multi-domain] Cd Length: 265 Bit Score: 290.94 E-value: 1.30e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 4 ENEQEWIG-GRNPVLEVLRSDRDIHKIYVQEGSQKGvLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQ 81
Cdd:COG0566 22 EEEGLFLAeGRHAVEEALKAGREIEELLVTEGALDR-LAELLALAKAAGIPVYEVSREVLDKLSGTEtHQGVLAVVRPPE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 82 YAELDDLFAAAEAKdemPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNM 161
Cdd:COG0566 101 YADLEDLLAEAGEP---PLLLVLDGVQDPGNLGAILRSAAAFGVDGVILPKRRADPYNPKVVRASAGALFHVPVARVTNL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 162 VRTMEELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:COG0566 178 ADALEELKEAGFWVVGTDLDGEASLYEVDLPGPVALVLGNEGKGLSRLVLEACDELVRIPMAGGVESLNVAVAAAILLYE 257
|
....*
gi 489820279 242 VYRKR 246
Cdd:COG0566 258 AARQR 262
|
|
| rRNA_methyl_3 |
TIGR00186 |
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases ... |
7-246 |
7.05e-91 |
|
rRNA methylase, putative, group 3; this is part of the trmH (spoU) family of rRNA methylases [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 129290 [Multi-domain] Cd Length: 237 Bit Score: 268.06 E-value: 7.05e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 7 QEWIGGRNPVLEVLRSDRDIHkiyVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQYAEL 85
Cdd:TIGR00186 1 QEYLYGKNAVLEALLNQQRVF---ILKGLESKRLKKLIQLAKKQGINIQLVDRQKLDQLTKGGnHQGIAAKVKPILYKDL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 86 DDLFAAAEAKDEmPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTM 165
Cdd:TIGR00186 78 NDLYKTAKSKKQ-PFLLILDEITDPHNLGAILRTAEAFGVDGVILPKRRSAPLNSTVVKTSSGAVEYVPLARVTNLSRTI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 166 EELQKRGLWIFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRK 245
Cdd:TIGR00186 157 TKLKESGFWTVGTDLDAQDTLYQVKLTKPLALVVGNEGEGVSRLIKENCDFLIKIPMAGKVDSLNVSVAAGILLFEIKRQ 236
|
.
gi 489820279 246 R 246
Cdd:TIGR00186 237 R 237
|
|
| SpoU-like_RlmB |
cd18103 |
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the ... |
100-242 |
5.22e-86 |
|
SAM-dependent rRNA methylase related to RlmB; 23S rRNA-M2G2251-MTase RlmB catalyzes the methylation of guanosine 2251, a modification conserved in the peptidyltransferase domain of 23S rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349976 Cd Length: 143 Bit Score: 251.92 E-value: 5.22e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTD 179
Cdd:cd18103 1 LLLILDGITDPHNLGAIIRSAEAFGVDGVIIPKRRSAPLTPTVAKASAGALEHLPIARVTNLARALEELKEAGFWIYGAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 180 AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
Cdd:cd18103 81 GEAEKSLYDVDLTGPLALVLGSEGKGLRRLVLKNCDFLVKIPMAGKVDSLNVSVAAGIILYEI 143
|
|
| PRK11181 |
PRK11181 |
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB; |
7-246 |
6.65e-70 |
|
23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB;
Pssm-ID: 183021 [Multi-domain] Cd Length: 244 Bit Score: 214.83 E-value: 6.65e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 7 QEWIGGRNPVLEVLRSD--RDIhKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQGVAAQVAAYQY- 82
Cdd:PRK11181 2 SEIIYGIHAVQALLERApeRFI-EVFVLKGREDKRLLPLINELEAQGIVIQLANRQTLDEKAEGAvHQGIIARVKPGRQl 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 83 --AELDDLFAaaeaKDEMPFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTN 160
Cdd:PRK11181 81 qeNDLPDLLA----SLEQPFLLILDGVTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAETVPLIRVTN 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 161 MVRTMEELQKRGLWIFGTdaKGSSDYRTMDVDM--PLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLL 238
Cdd:PRK11181 157 LARTMRMLQEKNIWIVGT--AGEADHTLYQSKLtgPLALVMGAEGEGMRRLTREHCDELISIPMAGSVSSLNVSVATGIC 234
|
....*...
gi 489820279 239 LYEVYRKR 246
Cdd:PRK11181 235 LFEAVRQR 242
|
|
| SpoU_methylase |
pfam00588 |
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet. |
99-240 |
1.11e-55 |
|
SpoU rRNA Methylase family; This family of proteins probably use S-AdoMet.
Pssm-ID: 425768 Cd Length: 142 Bit Score: 175.03 E-value: 1.11e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 99 PFFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGL-TQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFG 177
Cdd:pfam00588 1 PLVVVLDNIQDPGNLGAIIRTAAAFGADGLILVEPRSADPyNPKAIRASAGALFHLPLVVVDNLEEALKDLKEAGYAVVA 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 178 TDAKGSsDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLY 240
Cdd:pfam00588 81 TSLGGK-SLYEIDFPKKVALVFGNEGTGLSNEVLELCDRLVRIPMSGDVESLNVAVAAAIALY 142
|
|
| SpoU-like_rRNA-MTase |
cd18095 |
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
100-241 |
4.01e-52 |
|
SAM-dependent rRNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349968 Cd Length: 143 Bit Score: 166.06 E-value: 4.01e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTD 179
Cdd:cd18095 1 LVLVLDGVQDPGNLGTIIRTAAAFGVDGVILSKGTVDPYNPKVVRASMGALFRLPIIRVDDLEELLEELKEAGYKVVAAD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489820279 180 AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18095 81 LDGGSSLYDLDLPKPVALVLGNEGNGLSDELLELCDKRVTIPMSGGVESLNVAVAAAILLYE 142
|
|
| SpoU-like_MRM1 |
cd18105 |
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose ... |
100-241 |
5.50e-46 |
|
SAM-dependent rRNA methylase related to MRM1; MRM1 catalyzes the methylation of 2'-O-ribose residues G1145 to GmG residue of the mitochondrial 16S rRNA. MRM1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349978 Cd Length: 158 Bit Score: 150.75 E-value: 5.50e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGlW-IFGT 178
Cdd:cd18105 1 LWLLLDEITDPQNLGAILRSAYFLGVDGVVVSSKNSAPLSPVVSKASAGALELMPIYSVDNLASFLKSSKENG-WkVVGT 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489820279 179 DAK--GSSDYRTMDVDM--------PLAIVIGSEGFGMSRLVREKCDFLVHLPMRGK-----VTSLNASVAASLLLYE 241
Cdd:cd18105 80 SAPpsASSDKKTIPANElselllekPTILVLGNEGRGLRTNIKNLCDYLVSIPGGRSaenpgVDSLNVSVAAGILLHS 157
|
|
| SpoU-like_family |
cd18082 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
102-241 |
1.74e-40 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349955 Cd Length: 145 Bit Score: 136.20 E-value: 1.74e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTDAK 181
Cdd:cd18082 2 LVLDNIRSPGNIGSIFRTADAFGVEKIYLVGPTADIFDPKAKRTSRGTHFSVPYERVDNFEEYLKSLKEEGYPLIGLELT 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 182 GSSD---YRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18082 82 DGSIplsEFKFKKPKKIALIFGNERSGLSPELLALCDYTVHIPMSGKNSSLNVSVATGIALYE 144
|
|
| SpoU-like_RNA-MTase |
cd18104 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
100-246 |
1.09e-39 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349977 Cd Length: 146 Bit Score: 134.24 E-value: 1.09e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMvRTMEELQKRGLWIFGTD 179
Cdd:cd18104 1 LILVLEGLEKPGNLGAILRSADAAGADAVILCDPKTDLFNPNVIRASLGAVFTLPVAEASSE-ETLAWLKENKIRILATT 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489820279 180 AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246
Cdd:cd18104 80 PKAEKLYYEADLRGPIAIVVGSESEGLSEFWLKAADERVRIPMAGQADSLNVSVAAAILLYEALRQR 146
|
|
| SpoU-like_TrmH |
cd18092 |
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group ... |
102-246 |
1.90e-33 |
|
SAM-dependent tRNA methylase related to TrmH; TrmH catalyzes the transfer of the methyl group from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of the ribose of the universally conserved guanosine 18 (G18) position in tRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349965 Cd Length: 162 Bit Score: 118.72 E-value: 1.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVG---AHgIIIPKRRsvglTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGT 178
Cdd:cd18092 19 VVLENVHDPHNASAVLRTCDAFGvqdVH-VIEPKNK----FKKNRGVAMGADKWLDVHRHDSTEECLAALKEQGYRIVAT 93
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489820279 179 D-AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246
Cdd:cd18092 94 SlSPDAVPLDELDYTRPTALVFGNEKDGVSEEALAAADERVYIPMYGFVESLNVSVAAAIILYELQRQR 162
|
|
| SpoU-like |
cd18097 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
102-242 |
5.66e-31 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349970 Cd Length: 144 Bit Score: 111.89 E-value: 5.66e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIIIpkrrsVGLTQT-----VAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIF 176
Cdd:cd18097 3 VVLDNLRSAHNVGSIFRTADAAGVEKIYL-----CGYTPTpphpkVAKTALGAEESVPWEHFEDTLEAVRALKARGYTII 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489820279 177 GTD-AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
Cdd:cd18097 78 ALEtTENSVPLHEARLPRPLALVLGNEVRGVSPEVLALCDAVVEIPMFGRKNSLNVAVAAAVALYEL 144
|
|
| SpoU-like_AviRb |
cd18107 |
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes ... |
100-242 |
3.76e-30 |
|
SAM-dependent rRNA methylase related to AviRb; AviRb from Streptomyces viridochromogenes methylates the 2'-O atom of U2479 of the 23S ribosomal RNA. AviRb is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349980 Cd Length: 148 Bit Score: 109.79 E-value: 3.76e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKR-----GLW 174
Cdd:cd18107 1 LVVLFDRPTSPGNLGTIIRSADALGAHGLVVTGHAADVYDPKTIRASTGSLFSLPIVRVPSNRELEDWVEARkargtPLQ 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489820279 175 IFGTDAKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
Cdd:cd18107 81 LVGTDEHGDHQIADHDFTRPTLLLIGNETAGLSAAWRELCDETVSIPMAGSASSLNAACAASIFLYEA 148
|
|
| SpoU-like |
cd18096 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
100-241 |
9.04e-23 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349969 Cd Length: 140 Bit Score: 90.35 E-value: 9.04e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGIIIpkrrsVGLTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTD 179
Cdd:cd18096 1 LYLVLHNVAKRHNIGTIVRSANAFGVKEVHL-----VGRRKFNPFGAMGTDRHVKFRHFDTLAEAKEYLKERGIRLVGVE 75
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489820279 180 -AKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVT-SLNASVAASLLLYE 241
Cdd:cd18096 76 iVPGAEPIETHPFPGDTAFVLGNEGTGLSDEQLAICDGFVYIPQYGSGTaSLNVSVAASIVLHH 139
|
|
| PRK11081 |
PRK11081 |
tRNA guanosine-2'-O-methyltransferase; Provisional |
104-246 |
1.01e-22 |
|
tRNA guanosine-2'-O-methyltransferase; Provisional
Pssm-ID: 236837 [Multi-domain] Cd Length: 229 Bit Score: 92.75 E-value: 1.01e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 104 LDELEDPHNLGSIMRTADSVGAHGI--IIPKRRsvglTQTVAKASTGAMEYVPVVRVTNMVRTMEELQKRGLWIFGTDAK 181
Cdd:PRK11081 24 MEQVHKPHNVSAIIRTADAVGVHEVhaVWPGSR----MRTMGSTAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLS 99
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489820279 182 GSS-DYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246
Cdd:PRK11081 100 DTAvDFREIDYTRPTCILMGQEKTGISQEALALADQDIIIPMIGMVQSLNVSVASALILYEAQRQR 165
|
|
| SpoU-like_RNA-MTase |
cd18109 |
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes ... |
102-241 |
1.16e-22 |
|
SAM-dependent RNA methylase related to SpoU-TrmH; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349982 Cd Length: 141 Bit Score: 89.91 E-value: 1.16e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIII---------PKrrsvgltqtVAKASTGAMEYVPVVRvTNMVRTMEELQKRg 172
Cdd:cd18109 3 LALDGIQDPGNLGTIIRTADWFGIRQIICspdtvdpynPK---------VVQASMGSIFRVQIHY-TDLPALLAELKKA- 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 173 LWIFGTDAKGsSDYRTMDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVT-SLNASVAASLLLYE 241
Cdd:cd18109 72 FPVYGADLDG-ENLYEFTLPEKGILVMGNEGHGISPEVLKLLTHRLTIPRYGKGAeSLNVAVATAILLSE 140
|
|
| PRK10864 |
PRK10864 |
putative methyltransferase; Provisional |
90-245 |
1.85e-19 |
|
putative methyltransferase; Provisional
Pssm-ID: 236779 [Multi-domain] Cd Length: 346 Bit Score: 85.99 E-value: 1.85e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 90 AAAEAKDEMpffIILDELEDPHNLGSIMRTADSVGAHGIIIPkrrSVGLTQTVAKAST--GAMEYVPVVRVTNMVRTMEE 167
Cdd:PRK10864 192 AQAGAQDCV---LALEDVGNPHNLGGIMRSCAHFGVKGVVVQ---DAALLESGAAIRTaeGGAEHVQPITGDSFVDVLDD 265
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 168 LQKRGLWIFGTDA-KGSSDYRTmdvDMP--LAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYR 244
Cdd:PRK10864 266 FRQAGYTIVTTSShKGTPLFKA---SLPakMVLVLGQEYDGLSDAARQQGDLSVSIDGTGNVESLNVSVATGVLLAEWWR 342
|
.
gi 489820279 245 K 245
Cdd:PRK10864 343 Q 343
|
|
| SpoU-like_RNMTL1 |
cd18106 |
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) ... |
102-241 |
2.85e-18 |
|
SAM-dependent rRNA methylase related to RNMTL1; RNMTL1 (also known as HC90, MRM3 and RMTL1) catalyzes the methylation of 2'-O-ribose residues G1370 to GmG residue of the mitochondrial 16S rRNA. RNMTL1 is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349979 Cd Length: 148 Bit Score: 78.83 E-value: 2.85e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIIIPKRrSVGLTQT-VAKASTGAMEYVPVVRVTNMvRTMEELQKRGLWIFGTDA 180
Cdd:cd18106 3 VICDNIRDPGNLGSILRSAAAAGCSKVLLTKG-CVDPWEPkVLRAGAGAHFRLPIYGNLSW-DDIPNYLPDDSKVFLADN 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489820279 181 K-GSSDYRTMDVDM-PLAIVIGSEGFGMS----RLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18106 81 NlPVQPYDSIDYCSgPIVLVIGGETHGVSpeayKLAHSTGGSRVHIPLANGVDSLNSAVAASILLFE 147
|
|
| SpoU_sub_bind |
pfam08032 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
9-72 |
1.04e-17 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 429793 [Multi-domain] Cd Length: 74 Bit Score: 74.97 E-value: 1.04e-17
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489820279 9 WIGGRNPVLEVLRSDRDIHKIYVQEGSQKGVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQG 72
Cdd:pfam08032 1 LIYGRHAVLEALKSGPEIKKLYLTEGRRDPRLKELLKLAKERGIKVEEVDRKKLDKLSGTAnHQG 65
|
|
| SpoU_sub_bind |
smart00967 |
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose ... |
10-72 |
1.84e-13 |
|
RNA 2'-O ribose methyltransferase substrate binding; This domain is a RNA 2'-O ribose methyltransferase substrate binding domain.
Pssm-ID: 214943 [Multi-domain] Cd Length: 70 Bit Score: 63.71 E-value: 1.84e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489820279 10 IGGRNPVLEVLRSDRDIHKIYVQEGSQKgVLKQVLTLAKERKIQVQFVPKQKIEKVVSGA-HQG 72
Cdd:smart00967 1 IEGRHAVEEALKSGRRIKELYLTEGRAE-RLKELLKLAKERGIKVIEVSKKELDKLSGTAnHQG 63
|
|
| SpoU-like_TrmL |
cd18094 |
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL ... |
102-244 |
9.77e-13 |
|
SAM-dependent tRNA methylase related to TrmL; tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349967 Cd Length: 145 Bit Score: 63.63 E-value: 9.77e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGA--HgIIIP----------KRrsvgltqtvakastGAMEYVPVVRVTnMVRTMEELQ 169
Cdd:cd18094 2 IVLYEPEIPQNTGNIARTCAATGArlH-LIEPlgfslddkrlKR--------------AGLDYWDHVDLT-VHDSWEAFL 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 170 KRG----LWIFGTdaKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREKC-DFLVHLPMRGKVTSLNASVAASLLLYEVYR 244
Cdd:cd18094 66 EALppgrLFLFTT--KGTKPYTDFDFKPGDYLVFGRESTGLPEEILDAFpDRRLRIPMRPKVRSLNLSNSVAIVLYEALR 143
|
|
| SpoU-like_NHR |
cd18108 |
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) ... |
102-241 |
1.38e-12 |
|
Nosiheptide-resistance methyltransferase (NHR); Nosiheptide-resistance methyltransferase (NHR) confers resistance to the thiazole antibiotic nosiheptide via catalyzing 2'O-methylation of 23S rRNA at the nucleotide A1067. NHR is a member of the SPOUT (SpoU-TrmD) methyltransferase (MTase) superfamily, a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349981 Cd Length: 144 Bit Score: 63.27 E-value: 1.38e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIII--PKRRSVgLTQTVAKASTGAMEYVPVVrVTNMVRTMEELQKRGLWIFGTD 179
Cdd:cd18108 3 VVLDGVRIVGNIGAIVRTSLALGAAGIVLvdSDLATV-ADRRLLRASRGYVFSLPVV-LADREEAVAFLRDNDIPLMTLD 80
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489820279 180 AKGSSDYRTM-DVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18108 81 ADGDVPVKELgDRPDRLALVFGSEKGGPSGLFEEAAAGTVSIPMSSSTESLNVSVSAGIALHE 143
|
|
| SpoU-like_TRM3-like |
cd18091 |
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O) ... |
107-241 |
2.40e-11 |
|
SAM-dependent tRNA methylase related to TRM3; Yeast tRNA (guanosine(18)-2'-O)-methyltransferase TRM3 catalyzes the formation of 2'-O-methylguanosine at position 18 (Gm18) in various tRNAs. TRM3 is similar to C-terminal domain of TAR (HIV-1) RNA binding protein 1 (TARBP1), a protein binding to TAR, which functions as a RNA regulatory signal by forming a stable stem-loop structure to which transactivator protein Tat binds. The role of TARBP1 is believed to be to disengage RNA polymerase II from TAR during transcriptional elongation. TRM3 and the C-terminal methyltransferase domain of TARBP1 are members of the SPOUT methyltransferase superfamily.
Pssm-ID: 349964 Cd Length: 145 Bit Score: 59.85 E-value: 2.40e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 107 LEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTgAMEYVPV--VRVTNMVRTMEELQKRGLWIFGTDAKGSS 184
Cdd:cd18091 8 IDKPPNLGGLCRTCEIFGVSKLVLPNLAVVEDKQFKALSVS-AEKWLPIeeVKPEDLLPYLKEKKQEGYTIVGLEQTANS 86
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489820279 185 ----DYrtmDVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18091 87 vslhDF---QFPKKTVLVLGNEKEGIPAELLSLLDVCVEIPQLGVIRSLNVHVSGAIAIYE 144
|
|
| rRNA_methyl_1 |
TIGR00050 |
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of ... |
102-246 |
5.78e-10 |
|
RNA methyltransferase, TrmH family, group 1; This is part of the trmH (spoU) family of S-adenosyl-L-methionine (AdoMet)-dependent methyltransferases, and is now characterized, in E. coli, as a tRNA:Cm32/Um32 methyltransferase. It may be named TrMet(Xm32), or TrmJ, according to the nomenclature style chosen [Protein synthesis, tRNA and rRNA base modification]
Pssm-ID: 272876 [Multi-domain] Cd Length: 233 Bit Score: 57.79 E-value: 5.78e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKAStGAMEYVPVVRVtnmVRTMEELQKRGLWIFGTDAK 181
Cdd:TIGR00050 6 IVLVEPSHPGNIGSIARAMKNMGLTELRLVNPRVKLEEEAYALAA-GARDILDNAKV---VDTLDEALDDCDFVVGTSAR 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489820279 182 GSSDYRTM-----------DVDMPLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEVYRKR 246
Cdd:TIGR00050 82 SRNLQRPMltprelapklvAEKGKVALVFGREDSGLTNEELQKCHVLVSIPTSEEYPSLNLSHAVAVILYELRMAW 157
|
|
| TrmL |
COG0219 |
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ... |
102-244 |
1.93e-08 |
|
tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain [Translation, ribosomal structure and biogenesis]; tRNA(Leu) C34 or U34 (ribose-2'-O)-methylase TrmL, contains SPOUT domain is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 439989 Cd Length: 153 Bit Score: 51.96 E-value: 1.93e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIII-P----------KRrsvgltqtvakASTGAMEYVPVVRVTNMVRTMEELQK 170
Cdd:COG0219 4 IVLYEPEIPQNTGNIIRLCAATGARLHLIePlgfslddkklKR-----------AGLDYWELVDLTVHDSWEAFLEALPG 72
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489820279 171 RGLWIFGTdaKGSSDYRTMDVDMPLAIVIGSEGFGMSRLVREK-CDFLVHLPMRGKVTSLNASVAASLLLYEVYR 244
Cdd:COG0219 73 GRLFLFTT--KGTKPYTDVDYQPGDVLLFGRETAGLPEEVLAApADQRLRIPMRPGVRSLNLSNAVAIVLYEALR 145
|
|
| SpoU-like |
cd18098 |
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase ... |
100-240 |
2.36e-08 |
|
SAM-dependent rRNA or tRNA methylase related to SpoU; RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349971 Cd Length: 138 Bit Score: 51.49 E-value: 2.36e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 100 FFIILDELEDPHNLGSIMRTADSVGAHGII-IPKRRSVGLTQTVAKASTGAMeyvPVVRVTNMVRTMEELQKRGLWI--- 175
Cdd:cd18098 1 FAIGIENPKTPKNVGTLWRAAGCLGASFVFtIGARYKRRKQSTDTSKAWRHI---PLFHYDDLEDLAEPLPFGAVLVave 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 489820279 176 FGTDAKGSSDYRTMDvdmpLAI-VIGSEGFGMSRLVREKCDFLVHLPMRGkvtSLNASVAASLLLY 240
Cdd:cd18098 78 LTEGATPLPDFKHPD----RAVyLLGPEDGGLPQEVLARCHHVVYLPTRG---SLNVAVAGSIVLY 136
|
|
| SpoU-like_TrmJ |
cd18093 |
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl ... |
102-241 |
4.70e-07 |
|
SAM-dependent tRNA methylase related to TrmJ; tRNA methyltransferase TrmJ catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 32 in both tRNASer1 and tRNAGln2. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.
Pssm-ID: 349966 Cd Length: 153 Bit Score: 48.26 E-value: 4.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 102 IILDELEDPHNLGSIMRTADSVGAHGIIIPKRRSVGLTQTVAKASTGAMEYVPVVRVtnmVRTMEELQKRGLWIFGTDAK 181
Cdd:cd18093 3 VVLVEPQHPGNIGAVARAMKNFGLSDLRLVNPRCDDPEEAARALASGAEDVLENAKV---YDTLEEALADCDLVVATTAR 79
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489820279 182 GSSDYRTM-------------DVDMPLAIVIGSEGFGMSR--LvrEKCDFLVHLPMRGKVTSLNASVAASLLLYE 241
Cdd:cd18093 80 PRGLRRPLltprelaellkehAAGGKVALVFGREDSGLTNeeL--ALCDLLVTIPTNPEYPSLNLAQAVAIVLYE 152
|
|
| TrmJ |
COG0565 |
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ... |
187-244 |
2.02e-05 |
|
tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase [Translation, ribosomal structure and biogenesis]; tRNA C32,U32 (ribose-2'-O)-methylase TrmJ or a related methyltransferase is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 440331 [Multi-domain] Cd Length: 237 Bit Score: 44.34 E-value: 2.02e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489820279 187 RTMDVDMPLAIVIGSEGFGMSR--LvrEKCDFLVHLPMRGKVTSLNASVAASLLLYEVYR 244
Cdd:COG0565 100 LARAAGGKVALVFGRERSGLTNeeL--ALCDALVTIPTNPEYPSLNLAQAVQVVAYELRK 157
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| PRK15114 |
PRK15114 |
tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional |
194-242 |
2.43e-03 |
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tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ; Provisional
Pssm-ID: 185069 Cd Length: 245 Bit Score: 38.20 E-value: 2.43e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 489820279 194 PLAIVIGSEGFGMSRLVREKCDFLVHLPMRGKVTSLNASVAASLLLYEV 242
Cdd:PRK15114 108 PVALVFGRERVGLTNDELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEV 156
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