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Conserved domains on  [gi|489821753|ref|WP_003725552|]
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MULTISPECIES: molybdenum ABC transporter permease [Listeria]

Protein Classification

molybdate ABC transporter permease subunit( domain architecture ID 10790565)

molybdate ABC transporter permease subunit is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system involved in the transport of molybdenum

Gene Ontology:  GO:0043190|GO:0140359|GO:0042626|GO:0016020|GO:0015098|GO:0015689
PubMed:  25750732|24638992|18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 1-216 2.77e-56

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


:

Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 178.32  E-value: 2.77e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   1 MFTSVWHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLWDTFDF 80
Cdd:COG4149    5 DWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEELFGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  81 SFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGA 160
Cdd:COG4149   85 SLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGEFGA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489821753 161 SLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQ 216
Cdd:COG4149  165 TLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRRR 220
 
Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 1-216 2.77e-56

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 178.32  E-value: 2.77e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   1 MFTSVWHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLWDTFDF 80
Cdd:COG4149    5 DWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEELFGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  81 SFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGA 160
Cdd:COG4149   85 SLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGEFGA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489821753 161 SLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQ 216
Cdd:COG4149  165 TLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRRR 220
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 6-215 3.25e-33

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 118.50  E-value: 3.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753    6 WHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLwDTFDFSFIFS 85
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAWLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNGPIGKLL-ELFGISLVFT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   86 LSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASLMVA 165
Cdd:TIGR02141  80 FTGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEFGATLMFA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 489821753  166 GYIEGKTDTIASSIYFMVqQGDMRTAIYLGLINVIIGVFALLVIHVLTIR 215
Cdd:TIGR02141 160 GNIPGETQTIPLAIYDAV-ESDYELAHQLSLVLLAISLIVLLLVELLNKR 208
modB PRK09421
molybdate ABC transporter permease subunit;
53-216 5.07e-25

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 98.07  E-value: 5.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  53 PTVVGLVLLNVLGRNDFIGGVLWDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFT 132
Cdd:PRK09421  59 PVVTGYLLLISMGRRGFIGQWLYEWFGISFAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFF 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753 133 KIILPNCWQPILAGVLLSFCRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQ--GDMrTAIYLGLINVIIGVFALLVIH 210
Cdd:PRK09421 139 TITLPLTLPGIIAGTVLAFARSLGEFGATITFVSNIPGETQTIPSAMYTLIQTpgGES-AAARLCIISIAIALASLLLSE 217


                 ....*.
gi 489821753 211 VLTIRQ 216
Cdd:PRK09421 218 WLARRS 223
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 80-197 1.33e-09

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 55.63  E-value: 1.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  80 FSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIIlpncWQ---PILAGVLLSFCRAMG 156
Cdd:NF038017  66 LGLLYTPTAMIIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTLL----KEarfALLAAVLAGFGRAIS 141

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 489821753 157 EFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLI 197
Cdd:NF038017 142 EVGAVMMVGGNIRGYTRVLTTAIVLETSKGNFDLALALGII 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 6-203 3.14e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 3.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   6 WHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNvlgrndFIGGVLWDTFDFSFIFS 85
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVL------LFGVLLGWGILPGLGLP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  86 lsgAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASLMVA 165
Cdd:cd06261   76 ---ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489821753 166 GYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGV 203
Cdd:cd06261  153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 73-208 9.22e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 44.60  E-value: 9.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   73 VLWDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFC 152
Cdd:pfam00528  39 LVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFG 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 489821753  153 RAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLV 208
Cdd:pfam00528 119 GALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQ 174
 
Name Accession Description Interval E-value
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 1-216 2.77e-56

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 178.32  E-value: 2.77e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   1 MFTSVWHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLWDTFDF 80
Cdd:COG4149    5 DWSALWLSLKVALIATLLLLLLGIPLAWWLARTRFRGKGLLEALVTLPLVLPPTVLGFYLLLLFGRNGPLGQLLEELFGI 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  81 SFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGA 160
Cdd:COG4149   85 SLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVLAFARALGEFGA 164

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 489821753 161 SLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQ 216
Cdd:COG4149  165 TLMFAGNIPGKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRRR 220
modB_ABC TIGR02141
molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, ...
 6-215 3.25e-33

molybdate ABC transporter, permease protein; This model describes the permease protein, ModB, of the molybdate ABC transporter. This system has been characterized in E. coli, Staphylococcus carnosus, Rhodobacter capsulatus and Azotobacter vinlandii. Molybdate is chemically similar to sulfate, thiosulfate, and selenate. These related substrates, and sometimes molybdate itself, can be transported by the homologous sulfate receptor. Some apparent molybdenum transport operons include a permease related to this ModB, although less similar than some sulfate permease proteins and not included in this model. [Transport and binding proteins, Anions]


Pssm-ID: 273993 [Multi-domain]  Cd Length: 208  Bit Score: 118.50  E-value: 3.25e-33
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753    6 WHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLwDTFDFSFIFS 85
Cdd:TIGR02141   1 WLSLKVAVIATLLLLPLGIPVAWLLARSRFRGKPLLEVLVTLPLVLPPTVLGFYLLIAFGPNGPIGKLL-ELFGISLVFT 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   86 LSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASLMVA 165
Cdd:TIGR02141  80 FTGAVLASVIVSFPLMVQPIRAAFEAVDPDLEEAARTLGASESQTFLKVTLPLAFPGLLAGAVLSFARALGEFGATLMFA 159

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 489821753  166 GYIEGKTDTIASSIYFMVqQGDMRTAIYLGLINVIIGVFALLVIHVLTIR 215
Cdd:TIGR02141 160 GNIPGETQTIPLAIYDAV-ESDYELAHQLSLVLLAISLIVLLLVELLNKR 208
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 66-217 1.84e-30

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 112.92  E-value: 1.84e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  66 RNDFIGGVLwDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILA 145
Cdd:COG0555  117 PNGWLGQLL-APLGIKVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLT 195

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489821753 146 GVLLSFCRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQS 217
Cdd:COG0555  196 GFALAFARALGEFGAVIFIAGNLPMKTEILPLLIYLKLEEGDYAGATAIALVLLLISFLLLLLINLLQRRSR 267
modB PRK09421
molybdate ABC transporter permease subunit;
53-216 5.07e-25

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 98.07  E-value: 5.07e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  53 PTVVGLVLLNVLGRNDFIGGVLWDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFT 132
Cdd:PRK09421  59 PVVTGYLLLISMGRRGFIGQWLYEWFGISFAFSWRGAALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFF 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753 133 KIILPNCWQPILAGVLLSFCRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQ--GDMrTAIYLGLINVIIGVFALLVIH 210
Cdd:PRK09421 139 TITLPLTLPGIIAGTVLAFARSLGEFGATITFVSNIPGETQTIPSAMYTLIQTpgGES-AAARLCIISIAIALASLLLSE 217


                 ....*.
gi 489821753 211 VLTIRQ 216
Cdd:PRK09421 218 WLARRS 223
Mo_ABC_porter TIGR01581
NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively ...
 1-208 6.79e-25

NifC-like ABC-type porter; This model describes a clade of ABC porter genes with relatively weak homology compared to its neighbor clades, the molybdate (TIGR02141) and sulfate (TIGR00969) porters. Neighbor-Joining, PAM-distance phylogenetic trees support the separation of the clades in this way. Included in this group is a gene designated NifC in Clostridium pasturianum. It would be reasonable to presume that NifC acts as a molybdate porter since the most common form of nitrogenase is a molybdoenzyme. Several other sequences falling within the scope of this model are annotated as molybdate porters and one, from Halobacterium, is annotated as a sulfate porter. There is presently no experimental evidence to support annotations with this degree of specificity.


Pssm-ID: 130643  Cd Length: 225  Bit Score: 97.47  E-value: 6.79e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753    1 MFTSVWHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNVLGRNDFIGGVLwDTFDF 80
Cdd:TIGR01581  19 NIKALRLSLATSLASLLLAVIIGIPTAYVLARVRFPLKKLLDTLLDLPMVLPPLVAGLALLLLFGRNGLLGPYL-EAAGI 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   81 SFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGA 160
Cdd:TIGR01581  98 QVIFSTLGVVLAQTFVASPYYVRVARSTFKSVDPRYEDVARSLGAGPLETFRKITLPMARPGLLAGLVLAWARALGEFGA 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*...
gi 489821753  161 SLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLV 208
Cdd:TIGR01581 178 TLMFAGSIQGKTRTLPLAIYLNIQSDNIEAAVASALLLLVIAFLLLLV 225
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
2-215 1.67e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 74.43  E-value: 1.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   2 FTSVWHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILIllplvlpptvvglvllnvlgrndFIG---------- 71
Cdd:COG1178  337 LRALLNSLLLALLAALLAVLLALLLAYLVRRRRGRLARLLDRLA-----------------------MLPyavpgivlgl 393

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  72 GVLWdTFDFSFIFSLSGA----IVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGV 147
Cdd:COG1178  394 GLLL-LFNRPLPLLLYGTlailVLAYVVRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAA 472

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489821753 148 LLSFCRAMGEFGASLMVAGyieGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIR 215
Cdd:COG1178  473 LLVFVTSMKELSATLLLRP---PGFETLAVLIYQLASSGRYGEAAALALLLVLVSLLPVLLLERLLGR 537
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
66-222 9.13e-15

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 72.50  E-value: 9.13e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  66 RNDFIGGVLWDTFDFSF--IFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPI 143
Cdd:COG1178  117 PNGLLNTLLRALFGLEPpdIYGLGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAI 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753 144 LAGVLLSFCRAMGEFGASLMVAGYIegktDTIASSIY-FMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQSNLTRG 222
Cdd:COG1178  197 AAGALLVFLLCLADFGTPLVLGGGY----TTLTTAIYqAWLGDFDLGAAAALALVLLLLVLLLLLLERRLRRRRRYATVG 272
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
72-221 1.38e-13

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 67.86  E-value: 1.38e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  72 GVLWDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSF 151
Cdd:PRK10971 126 GEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSF 205

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753 152 CRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAiylGLINVIIGVFALLVIHVLTIRQSNLTR 221
Cdd:PRK10971 206 TRSLGEFGAVIFIAGNIAWKTEVTSLMIFVRLQEFDYPAA---SAIASVILAASLLLLFSINTLQSRFGR 272
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 85-216 1.30e-12

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 65.13  E-value: 1.30e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  85 SLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASLMV 164
Cdd:COG1177  130 GLWGLILAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFL 209

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 489821753 165 AGyieGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQ 216
Cdd:COG1177  210 AG---PGVTTLPVYIYSMIRRGISPEINALSTLLILLSLLLLLLAERLRRRG 258
cysT CHL00187
sulfate transport protein; Provisional
 66-185 1.67e-12

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 64.27  E-value: 1.67e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  66 RNDFIGGVLWdTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILA 145
Cdd:CHL00187 118 DNGWIGHLLS-HLGIQIVFTKLGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLT 196

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 489821753 146 GVLLSFCRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQ 185
Cdd:CHL00187 197 GLALTFSRAIGEYGSIVIISSNIPFKDLVASVLIFQSLEQ 236
CysW COG4208
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 66-175 7.74e-12

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443356  Cd Length: 281  Bit Score: 62.82  E-value: 7.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  66 RNDFIGGVLwDTFDFSFIFSLSGAIVATTII--------ILPIMY-QGlksaflsIDHELvwAAETLSANKKQIFTKIIL 136
Cdd:COG4208  126 AQGWFGPWL-EAHDIKIIFAVPGIVLATIFVtfpfvareLIPLMQeQG-------TDEEE--AALTLGASGWQTFWRVTL 195

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 489821753 137 PNCWQPILAGVLLSFCRAMGEFGASLMVAGYIEGKTDTI 175
Cdd:COG4208  196 PNIKWGLLYGVILCNARAMGEFGAVSVVSGHIRGETNTL 234
permease_CysW TIGR02140
sulfate ABC transporter, permease protein CysW; This model represents CysW, one of two ...
 66-216 8.37e-12

sulfate ABC transporter, permease protein CysW; This model represents CysW, one of two homologous, tandem permeases in the sulfate ABC transporter system; the other is CysT (TIGR02139). The sulfate transporter has been described in E. coli as transporting sulfate, thiosulfate, selenate, and selenite. Sulfate transporters may also transport molybdate ion if a specific molybdate transporter is not present. [Transport and binding proteins, Anions]


Pssm-ID: 162725  Cd Length: 261  Bit Score: 62.79  E-value: 8.37e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   66 RNDFIGGVLWDtFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILA 145
Cdd:TIGR02140 110 SQGWLGPWLED-LDIKIIFSLPGIVLATMFVTCPFVARELIPVMEEQGTEQEEAALTLGASWWQTFWRVTLPNIKWGLLY 188

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489821753  146 GVLLSFCRAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLVIHVLTIRQ 216
Cdd:TIGR02140 189 GVILCNARAMGEFGAVSVVSGHIRGKTNTLPLHVELLYNEYQSYAAFAAASLLALLALVTLVLKAILERRQ 259
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 80-186 7.85e-10

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 57.46  E-value: 7.85e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  80 FSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFG 159
Cdd:COG1176  148 LRLLYTEFAVVIGLVYVYLPFMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFV 227

                         90       100
                 ....*....|....*....|....*..
gi 489821753 160 ASLMVAGyieGKTDTIASSIYFMVQQG 186
Cdd:COG1176  228 TPALLGG---GKVLMIGNLIYQQFLSA 251
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 80-197 1.33e-09

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 55.63  E-value: 1.33e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  80 FSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIIlpncWQ---PILAGVLLSFCRAMG 156
Cdd:NF038017  66 LGLLYTPTAMIIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTLL----KEarfALLAAVLAGFGRAIS 141

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 489821753 157 EFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLI 197
Cdd:NF038017 142 EVGAVMMVGGNIRGYTRVLTTAIVLETSKGNFDLALALGII 182
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 6-203 3.14e-09

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 54.59  E-value: 3.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   6 WHTLLVATISTFLAFMTMLPLSYYFAGRKSRFQLPVEILILLPLVLPPTVVGLVLLNvlgrndFIGGVLWDTFDFSFIFS 85
Cdd:cd06261    2 LNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVL------LFGVLLGWGILPGLGLP 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  86 lsgAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASLMVA 165
Cdd:cd06261   76 ---ALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLG 152

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 489821753 166 GYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGV 203
Cdd:cd06261  153 GGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
cysW PRK11602
sulfate/thiosulfate ABC transporter permease CysW;
67-175 4.37e-09

sulfate/thiosulfate ABC transporter permease CysW;


Pssm-ID: 183225  Cd Length: 283  Bit Score: 55.14  E-value: 4.37e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  67 NDFIGGVLwDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAG 146
Cdd:PRK11602 128 NGPLGGWL-DEHNLQLMFSWPGMVLVTIFVTCPFVVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYG 206

                         90       100
                 ....*....|....*....|....*....
gi 489821753 147 VLLSFCRAMGEFGASLMVAGYIEGKTDTI 175
Cdd:PRK11602 207 VVLTNARAIGEFGAVSVVSGSIRGETLSL 235
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 80-159 5.39e-07

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 49.23  E-value: 5.39e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  80 FSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFG 159
Cdd:PRK15050 155 LDFLYSPGGVILAEITFYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFG 234
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 83-166 9.11e-07

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 48.53  E-value: 9.11e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  83 IFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMGEFGASL 162
Cdd:PRK09497 147 MFTESAVIIGLVYILLPFMVLPLYSSIEKLDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSD 226


                 ....
gi 489821753 163 MVAG 166
Cdd:PRK09497 227 LLGG 230
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 73-208 9.22e-06

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 44.60  E-value: 9.22e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   73 VLWDTFDFSFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFC 152
Cdd:pfam00528  39 LVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFG 118

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 489821753  153 RAMGEFGASLMVAGYIEGKTDTIASSIYFMVQQGDMRTAIYLGLINVIIGVFALLV 208
Cdd:pfam00528 119 GALGGAVLLEFLGSWPGLGLLLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQ 174
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 84-208 1.65e-04

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 41.29  E-value: 1.65e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753  84 FSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILAGVLLSFCRAMgefgASLM 163
Cdd:COG0600  123 IGEASKIFVIFLGAFFPILLNTAAGVRSVDPELLELARSLGASRWQILRKVVLPAALPYIFTGLRIALGLAW----IGLV 198

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 489821753 164 VAGYIeGKTDTIASSIYFMVQQGDMrTAIYLGLInvIIGVFALLV 208
Cdd:COG0600  199 VAELL-GASSGLGYLILDARQLLDT-DLVFAAIL--VIGLLGLLL 239
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 68-166 8.05e-04

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 39.56  E-value: 8.05e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489821753   68 DFIGGVLWDTFDF--SFIFSLSGAIVATTIIILPIMYQGLKSAFLSIDHELVWAAETLSANKKQIFTKIILPNCWQPILA 145
Cdd:TIGR02138 131 PHFQPFLGSNLGLipLFGGPILTAGIVLAIMILPTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVG 210

                          90       100
                  ....*....|....*....|.
gi 489821753  146 GVLLSFCRAMGEFGASLMVAG 166
Cdd:TIGR02138 211 AVVLGLGRALGETMAVTMVIG 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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