CobD/CbiB family cobalamin biosynthesis protein converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group; similar to cobalamin biosynthesis proteins CobD and CbiB
Cobalamin biosynthesis protein CobD/CbiB [Coenzyme transport and metabolism]; Cobalamin ...
1-316
3.55e-136
Cobalamin biosynthesis protein CobD/CbiB [Coenzyme transport and metabolism]; Cobalamin biosynthesis protein CobD/CbiB is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440881 [Multi-domain] Cd Length: 318 Bit Score: 388.36 E-value: 3.55e-136
CobD/Cbib protein; This family includes CobD proteins from a number of bacteria, in Salmonella ...
10-297
2.43e-129
CobD/Cbib protein; This family includes CobD proteins from a number of bacteria, in Salmonella this protein is called Cbib. Salmonella CobD is a different protein. This protein is involved in cobalamin biosynthesis and is probably an enzyme responsible for the conversion of adenosylcobyric acid to adenosylcobinamide or adenosylcobinamide phosphate.
Pssm-ID: 460839 [Multi-domain] Cd Length: 280 Bit Score: 369.86 E-value: 2.43e-129
cobalamin biosynthesis protein CobD; This protein is involved in cobalamin (vitamin B12) ...
8-315
2.82e-66
cobalamin biosynthesis protein CobD; This protein is involved in cobalamin (vitamin B12) biosynthesis and porphyrin biosynthesis. It converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. It is part of the cob operon. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 273045 Cd Length: 305 Bit Score: 210.08 E-value: 2.82e-66
Cobalamin biosynthesis protein CobD/CbiB [Coenzyme transport and metabolism]; Cobalamin ...
1-316
3.55e-136
Cobalamin biosynthesis protein CobD/CbiB [Coenzyme transport and metabolism]; Cobalamin biosynthesis protein CobD/CbiB is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 440881 [Multi-domain] Cd Length: 318 Bit Score: 388.36 E-value: 3.55e-136
CobD/Cbib protein; This family includes CobD proteins from a number of bacteria, in Salmonella ...
10-297
2.43e-129
CobD/Cbib protein; This family includes CobD proteins from a number of bacteria, in Salmonella this protein is called Cbib. Salmonella CobD is a different protein. This protein is involved in cobalamin biosynthesis and is probably an enzyme responsible for the conversion of adenosylcobyric acid to adenosylcobinamide or adenosylcobinamide phosphate.
Pssm-ID: 460839 [Multi-domain] Cd Length: 280 Bit Score: 369.86 E-value: 2.43e-129
cobalamin biosynthesis protein CobD; This protein is involved in cobalamin (vitamin B12) ...
8-315
2.82e-66
cobalamin biosynthesis protein CobD; This protein is involved in cobalamin (vitamin B12) biosynthesis and porphyrin biosynthesis. It converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. It is part of the cob operon. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 273045 Cd Length: 305 Bit Score: 210.08 E-value: 2.82e-66
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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The thumbnail image, if present, provides an approximate view of the feature's location in 3 dimensions.
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Functional characterization of the conserved domain architecture found on the query.
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This image shows a graphical summary of conserved domains identified on the query sequence.
The Show Concise/Full Display button at the top of the page can be used to select the desired level of detail: only top scoring hits
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Domains are color coded according to superfamilies
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Others (non-specific hits) and
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if a domain or superfamily has been annotated with functional sites (conserved features),
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click on the bars or triangles to view your query sequence embedded in a multiple sequence alignment of the proteins used to develop the corresponding domain model.
The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
Click on the domain model's accession number to view the multiple sequence alignment of the proteins used to develop the corresponding domain model.
To view your query sequence embedded in that multiple sequence alignment, click on the colored bars in the Graphical Summary portion of the search results page,
or click on the triangles, if present, that represent functional sites (conserved features)
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Concise Display shows only the best scoring domain model, in each hit category listed below except non-specific hits, for each region on the query sequence.
(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
(labeled illustration) Full Display shows all domain models, in each hit category below, that meet or exceed the RPS-BLAST threshold for statistical significance.
(labeled illustration) Four types of hits can be shown, as available,
for each region on the query sequence:
specific hits meet or exceed a domain-specific e-value threshold
(illustrated example)
and represent a very high confidence that the query sequence belongs to the same protein family as the sequences use to create the domain model
non-specific hits
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the domain superfamily to which the specific and non-specific hits belong
multi-domain models that were computationally detected and are likely to contain multiple single domains
Retrieve proteins that contain one or more of the domains present in the query sequence, using the Conserved Domain Architecture Retrieval Tool
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