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Conserved domains on  [gi|489862341|ref|WP_003765965|]
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ABC transporter permease [Listeria innocua]

Protein Classification

ABC transporter permease( domain architecture ID 10003093)

ABC transporter permease is the transmembrane subunit found in a periplasmic binding protein (PBP)-dependent ABC transport system, which may be involved in the transport of one or more from a variety of substrates including sugars, ions, amino acids, and peptides, among others

Gene Ontology:  GO:0055085|GO:0140359|GO:0042626|GO:0016020
PubMed:  31571164|27273632|26517919|18535149|17723295|25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 3-269 2.12e-86

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


:

Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 258.92  E-value: 2.12e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFD------VDGNFTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLLIS 75
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  76 YPTAYLLTKL--KHKQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFTDFSFLFVSTYIFIP 151
Cdd:COG1176   88 YPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYVYLP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 152 FMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEH 231
Cdd:COG1176  168 FMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQ 247

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489862341 232 FLVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGARK 269
Cdd:COG1176  248 FLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLL 285
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 3-269 2.12e-86

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 258.92  E-value: 2.12e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFD------VDGNFTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLLIS 75
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  76 YPTAYLLTKL--KHKQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFTDFSFLFVSTYIFIP 151
Cdd:COG1176   88 YPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYVYLP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 152 FMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEH 231
Cdd:COG1176  168 FMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQ 247

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489862341 232 FLVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGARK 269
Cdd:COG1176  248 FLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLL 285
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 14-258 9.58e-52

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 170.25  E-value: 9.58e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  14 VLWILLFVVAPILLIVYYSFFDVDGN------FTVDNYIHFFTPVYLKMTASSFWYAFLITVFTLLISYPTAYLLTKLKH 87
Cdd:PRK09497  16 VGWLVLFVFLPNLMIIGTSFLTRDDAnfvkmvFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAKLPH 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  88 K--QLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFTDFSFLFVSTYIFIPFMILPIFNAIEE 163
Cdd:PRK09497  96 KvrPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTpiRIMFTESAVIIGLVYILLPFMVLPLYSSIEK 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 164 INPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEHFLVTQDWGMGST 243
Cdd:PRK09497 176 LDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAA 255

                        250
                 ....*....|....*
gi 489862341 244 IGVFLIIAMILIMFL 258
Cdd:PRK09497 256 TSITLTIVMGLMLLV 270
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 14-254 4.74e-15

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 74.33  E-value: 4.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   14 VLWILLFVVAPILLIVYYSFFDVDGNFT-VDNYIHFF-TPVYLKMTASSFWYAFLITVFTLLISYPTAYLLTK--LKHKQ 89
Cdd:TIGR03262  11 ILALLLFLLLPLLALLTKSVYDSDGDFIgLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRsrIPGKG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   90 LWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGI-GSKQILFTDFSFLFvstyifiPFMILPIFNAIEEINPTL 168
Cdd:TIGR03262  91 AFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIyGFWGIVIGEVFYTF-------PHALMILVTALSLADGRL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  169 IQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVItLGTAIEEHFLVTQDWGMGSTIGVFL 248
Cdd:TIGR03262 164 YEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNV-LATDIYKQVIGQQNFPMGAVVGVLL 242


                  ....*.
gi 489862341  249 IIAMIL 254
Cdd:TIGR03262 243 LLPALL 248
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 60-255 7.56e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 45.35  E-value: 7.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  60 SFWYAFLITVFTLLISYPTAYLLTKLKHKQLWLLLIILPTWINLLLKAYAFIGIFGTygaanqfleILGIGSKQILFTDF 139
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF---------GVLLGWGILPGLGL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 140 SFLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGN 219
Cdd:cd06261   75 PALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 489862341 220 RVITLGTAIEEHFLVTQDWGMGSTIGVFLIIAMILI 255
Cdd:cd06261  155 EAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 3-269 2.12e-86

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 258.92  E-value: 2.12e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFD------VDGNFTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLLIS 75
Cdd:COG1176    8 RLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTrdpyggVVPGFTLENYARLFTdPLYLKVLLRTLWIALLTTLICLLLG 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  76 YPTAYLLTKL--KHKQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFTDFSFLFVSTYIFIP 151
Cdd:COG1176   88 YPIAYFLARAppRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFAVVIGLVYVYLP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 152 FMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEH 231
Cdd:COG1176  168 FMVLPLYAALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVTPALLGGGKVLMIGNLIYQQ 247

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 489862341 232 FLVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGARK 269
Cdd:COG1176  248 FLSALNWPLAAALAVVLLLIVLLVLLLYLRLLRRRRLL 285
potB PRK09497
spermidine/putrescine ABC transporter membrane protein; Reviewed
 14-258 9.58e-52

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 181910  Cd Length: 285  Bit Score: 170.25  E-value: 9.58e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  14 VLWILLFVVAPILLIVYYSFFDVDGN------FTVDNYIHFFTPVYLKMTASSFWYAFLITVFTLLISYPTAYLLTKLKH 87
Cdd:PRK09497  16 VGWLVLFVFLPNLMIIGTSFLTRDDAnfvkmvFTLDNYTRLLDPLYAEVLLHSLNMALIATLACLVLGYPFAWFLAKLPH 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  88 K--QLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFTDFSFLFVSTYIFIPFMILPIFNAIEE 163
Cdd:PRK09497  96 KvrPLLLFLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTpiRIMFTESAVIIGLVYILLPFMVLPLYSSIEK 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 164 INPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEHFLVTQDWGMGST 243
Cdd:PRK09497 176 LDKPLLEAARDLGANKLQTFIRIIIPLTMPGIIAGCLLVLLPAMGMFYVSDLLGGAKNLLIGNVIKSQFLNIRDWPFGAA 255

                        250
                 ....*....|....*
gi 489862341 244 IGVFLIIAMILIMFL 258
Cdd:PRK09497 256 TSITLTIVMGLMLLV 270
PRK10683 PRK10683
putrescine transporter subunit: membrane component of ABC superfamily; Provisional
 1-254 3.83e-35

putrescine transporter subunit: membrane component of ABC superfamily; Provisional


Pssm-ID: 182646  Cd Length: 317  Bit Score: 128.29  E-value: 3.83e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   1 MNRRTRTVYLVPYvLWILLFVVAPILLIVYYSFFDV--------------DGNFTV----DNYIHFFT-PVYLKMTASSF 61
Cdd:PRK10683  25 MKHGRKLVIALPY-LWLILLFLLPFLIVFKISLAEMaraippytdlmewaDGQLSItlnlGNFLQLTDdPLYFDAYLQSL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  62 WYAFLITVFTLLISYPTAYLL--TKLKHKQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIGSK--QILFT 137
Cdd:PRK10683 104 QVAAISTLCCLLIGYPLAWAVahSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKNNGVLNNFLLWLGVIDQplTILHT 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 138 DFSFLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIA 217
Cdd:PRK10683 184 NLAVYIGIVYAYLPFMVLPIYTALTRIDYSLVEAALDLGARPLKTFFSVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLG 263

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489862341 218 GNRVITLGTAIEEHFLVTQDWGMGSTIGVFLIIAMIL 254
Cdd:PRK10683 264 GPDSIMIGRVLWQEFFNNRDWPVASAVAIIMLLLLIV 300
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
3-258 9.83e-27

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 108.32  E-value: 9.83e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFDVDGNFTvdnyIHFFTPVYLKMTASSFWYAFLITVFTLLISYPTAYLL 82
Cdd:COG1178    6 RRRPRLLLLLLALLLALLVLLPLLALLLRAFTDGLANFW----ALLSDPYLWRALGNTLLLALLVTLLSLLLGVPLAWLL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  83 --TKLKHKQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFL-EILGIGSKQIlFTDFSFLFVSTYIFIPFMILPIFN 159
Cdd:COG1178   82 arTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLrALFGLEPPDI-YGLGGIILVLVLFNYPYVYLLLRA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 160 AIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGnRVITLGTAIEEHFLVTQDWG 239
Cdd:COG1178  161 ALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLVFLLCLADFGTPLVLGG-GYTTLTTAIYQAWLGDFDLG 239

                        250
                 ....*....|....*....
gi 489862341 240 MGSTIGVFLIIAMILIMFL 258
Cdd:COG1178  240 AAAALALVLLLLVLLLLLL 258
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
2-258 3.33e-21

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 90.19  E-value: 3.33e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   2 NRRTRTVYLVPYVLWILLFVVAPILLIVYYSFFDVDGNFTV------DNYIHFFT-PVYLKMTASSFWYAFLITVFTLLI 74
Cdd:COG1175   16 RRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWNLLGPPpefvglDNYARLFTdPRFWNALGNTLLFTVVSVPLQLVL 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  75 SYPTAYLLT-KLKHKQLWLLLIILPTWINLLLKAYAFIGIF-GTYGAANQFLEILGIGSKQILFTD----FSFLFVSTYI 148
Cdd:COG1175   96 GLLLALLLNrKLRGRGFFRTLFFLPWVISPVVVALIWKWLFnPDYGLLNALLGALGLEPINWLGDPslalPAVIIVTVWK 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 149 FIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTAdgvksgcqavfiPALSLFMITRLIA----------- 217
Cdd:COG1175  176 GTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLR------------PTILFVLVLSTIGalqvfdlvyvl 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 489862341 218 -----GNRVITLGTAIEEHFLVTQDWGMGSTIGVFLIIAMILIMFL 258
Cdd:COG1175  244 tgggpGNSTTTLVLYIYQTAFQQFDFGYASAIAVVLFLIILVLTLL 289
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 2-269 4.72e-21

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 89.40  E-value: 4.72e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   2 NRRTRTVYLVPYVLWILLFVVAPILLIVYYSFFDVDGN------FTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLLI 74
Cdd:COG1177    1 SSRLGRLLLRLFLALVLLFLYLPILVLVLYSFNDSWFLtfppegFTLRWYAELFSdPRLLDALLNSLLIALLSTLLATVL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  75 SYPTAYLLTKLKH--KQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIgskQILFTdfsflfvstyifIPF 152
Cdd:COG1177   81 GTPAALALARYRFrgRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILA---HVVFT------------LPF 145

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 153 MILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEhF 232
Cdd:COG1177  146 VVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFTLSFDEFVITLFLAGPGVTTLPVYIYS-M 224

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 489862341 233 LVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGARK 269
Cdd:COG1177  225 IRRGISPEINALSTLLILLSLLLLLLAERLRRRGERR 261
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
3-258 5.03e-17

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 80.21  E-value: 5.03e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFD-VDGNFTVDNYIH-FFTPVYLKMTASSFWYAFLITVFTLLISYPTAY 80
Cdd:COG1178  284 GRWRWLALALCLLLVLLGLLLPLLALLLWSLTKaLDDNLTLDNYRFvLLDPSLLRALLNSLLLALLAALLAVLLALLLAY 363

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  81 LLTKLKHK--QLWLLLIILPtwinlllkaYAFIGI---FGTYGAANQFLEILGIGSKQILftdfsfLFVSTYIFIPFMIL 155
Cdd:COG1178  364 LVRRRRGRlaRLLDRLAMLP---------YAVPGIvlgLGLLLLFNRPLPLLLYGTLAIL------VLAYVVRFLPFALR 428

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 156 PIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTAIEEhFLVT 235
Cdd:COG1178  429 SLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKELSATLLLRPPGFETLAVLIYQ-LASS 507

                        250       260
                 ....*....|....*....|...
gi 489862341 236 QDWGMGSTIGVFLIIAMILIMFL 258
Cdd:COG1178  508 GRYGEAAALALLLVLVSLLPVLL 530
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 14-259 5.89e-17

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 78.25  E-value: 5.89e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  14 VLWILLFVVAPILLIVYYSFfdvdgNFTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLLISYPTAYLLTKLKHKQLWL 92
Cdd:COG0555   17 LLYLSLIVLLPLAALVLKAA-----GLGWAEFWAVLTsPRVLAALKLSLGTALIAALINLVFGLPLAWVLVRYRFPGKRL 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  93 L--LIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIgskQILFTDFSFLFVSTYIFIPFMILPIFNAIEEINPTLIQ 170
Cdd:COG0555   92 VdaLVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGI---KVAFTPLGIVLAQTFVSLPFVVRTVQPVLEELDPELEE 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 171 ASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGN---RVITLGTAIEEHfLVTQDWGMGSTIGVF 247
Cdd:COG0555  169 AAATLGASRWQTFRRVILPLLLPALLTGFALAFARALGEFGAVIFIAGNlpmKTEILPLLIYLK-LEEGDYAGATAIALV 247

                        250
                 ....*....|..
gi 489862341 248 LIIAMILIMFLT 259
Cdd:COG0555  248 LLLISFLLLLLI 259
ModB COG4149
ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and ...
 48-268 9.88e-16

ABC-type molybdate transport system, permease component ModB [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, permease component ModB is part of the Pathway/BioSystem: Molybdopterin biosynthesis


Pssm-ID: 443320 [Multi-domain]  Cd Length: 223  Bit Score: 73.93  E-value: 9.88e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  48 FFTPVYLkmtasSFWYAFLITVFTLLISYPTAYLLTKLKH--KQLWLLLIILPtwinLLLK----AYAFIGIFGTYGAAN 121
Cdd:COG4149    5 DWSALWL-----SLKVALIATLLLLLLGIPLAWWLARTRFrgKGLLEALVTLP----LVLPptvlGFYLLLLFGRNGPLG 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 122 QFLEILGIGskQILFTDFSFLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQA 201
Cdd:COG4149   76 QLLEELFGI--SLVFTWTGAVLASVVVSLPLMVQPLRAAFEAVDPRLEEAARTLGASPWRVFFRVTLPLAKPGILAGAVL 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 202 VFIPALSLFMITRLIAGN---RVITLGTAIEEHFLVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGAR 268
Cdd:COG4149  154 AFARALGEFGATLMFAGNipgKTQTLPLAIYDAVEAGDYAAAHALSLILLAISFVVLLLLNLLNRRRRRR 223
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 14-254 4.74e-15

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 74.33  E-value: 4.74e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   14 VLWILLFVVAPILLIVYYSFFDVDGNFT-VDNYIHFF-TPVYLKMTASSFWYAFLITVFTLLISYPTAYLLTK--LKHKQ 89
Cdd:TIGR03262  11 ILALLLFLLLPLLALLTKSVYDSDGDFIgLANFAEYFaTPGLLQSLGNSLTVSAIVTAIVVPLAFAFAYALTRsrIPGKG 90

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   90 LWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGI-GSKQILFTDFSFLFvstyifiPFMILPIFNAIEEINPTL 168
Cdd:TIGR03262  91 AFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIyGFWGIVIGEVFYTF-------PHALMILVTALSLADGRL 163

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  169 IQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVItLGTAIEEHFLVTQDWGMGSTIGVFL 248
Cdd:TIGR03262 164 YEAARAMGASPWRTFFTVTLPGAKYGLISAAFVVFTLVITDFGVPKVIGGDYNV-LATDIYKQVIGQQNFPMGAVVGVLL 242


                  ....*.
gi 489862341  249 IIAMIL 254
Cdd:TIGR03262 243 LLPALL 248
PRK15050 PRK15050
2-aminoethylphosphonate transport system permease PhnU; Provisional
 3-259 1.96e-12

2-aminoethylphosphonate transport system permease PhnU; Provisional


Pssm-ID: 237888 [Multi-domain]  Cd Length: 296  Bit Score: 65.80  E-value: 1.96e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWILLFVVAPILLIVYYSFFDvDGNFTVDNYIHFFT-PVYLKMTASSFWYAFLITVFTLL-------- 73
Cdd:PRK15050  21 RLRPLLWLLLPLLVLAPLVVYPLVRVVLQSLTG-EHGLGLATYRAVLGsPDFRGALLTTLQIAFASTAGCLVlgvllalv 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  74 ---ISYPTAYLLTKLKHkqlwlLLIILPTWinllLKAYAFIGIFGTYGAAN---QFLEILGIGSKQILFTDFSFLFVSTY 147
Cdd:PRK15050 100 lafVPFPGASLVGRFID-----TFVAFPSF----LITLAFTFLYGSAGSVNialQRLFGLEAPPLDFLYSPGGVILAEIT 170

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 148 IFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGNRVITLGTA 227
Cdd:PRK15050 171 FYTPFVVRPLLAAFAQLDARQLEAAASLGASPWRVARRVILPEAWPALAAGGSLCLLLTLNEFGIVLFTGAKDVVTLPVL 250

                        250       260       270
                 ....*....|....*....|....*....|..
gi 489862341 228 IEEHFLVTQDWGMGSTIGVfLIIAMILIMFLT 259
Cdd:PRK15050 251 IYSKAIVDFDYPTACAIAV-VNLALSLGLYAL 281
cysT CHL00187
sulfate transport protein; Provisional
 14-219 3.54e-09

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 55.79  E-value: 3.54e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  14 VLWILLFVVAPILLIVYYSFFDVDGNFtvdnYIHFFTPVYLKMTASSFWYAFLITVFTLLISYPTAYLLTK--LKHKQLW 91
Cdd:CHL00187  18 LSYIIFLLVLPILALLIKASQQPWSDF----LQKATEPIALSAYSLTLSMALIAALINGFFGLLIAWVLVRynFPGKRLL 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  92 LLLIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIgskQILFTDFSFLFVSTYIFIPFMILPIFNAIEEINPTLIQA 171
Cdd:CHL00187  94 DAAVDLPFALPTSVAGLTLATVYGDNGWIGHLLSHLGI---QIVFTKLGVLLAMIFVSFPFVVRTIQPVLQEIEKELEEA 170

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 489862341 172 SRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGN 219
Cdd:CHL00187 171 AWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGEYGSIVIISSN 218
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 3-190 4.28e-06

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 47.01  E-value: 4.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341   3 RRTRTVYLVPYVLWIL--LFVVAPILLIVYYSFFDVD-----------GNFTVDNYIHFFTPV-YLKMTASSFWYAFLIT 68
Cdd:COG0395    8 RRRRLGRILLYLLLILlaLLFLFPLYWMVVTSFKPPAeifsgppsllpSEFTLENYRAAFTDGpFGRYLLNSLIVAVVST 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  69 VFTLLISYPTAYLLTKL--KHKQLWLLLIILPTWINL------LLKAYAFIGIFGTYgaanqfleilgigskqilftdFS 140
Cdd:COG0395   88 VLSLLLSSLAAYALARFrfRGRKLLFLLILATLMIPGqvllipLYLLFRQLGLLNTY---------------------WG 146

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|
gi 489862341 141 FLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPL 190
Cdd:COG0395  147 LILPYLAFGLPFGIFLLRQFFRSIPRELEEAARIDGASEFRIFWRIVLPL 196
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 60-255 7.56e-06

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 45.35  E-value: 7.56e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  60 SFWYAFLITVFTLLISYPTAYLLTKLKHKQLWLLLIILPTWINLLLKAYAFIGIFGTygaanqfleILGIGSKQILFTDF 139
Cdd:cd06261    4 TLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLF---------GVLLGWGILPGLGL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 140 SFLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGN 219
Cdd:cd06261   75 PALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGG 154

                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 489862341 220 RVITLGTAIEEHFLVTQDWGMGSTIGVFLIIAMILI 255
Cdd:cd06261  155 EAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
64-269 2.82e-05

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 44.36  E-value: 2.82e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  64 AFLITVFTLLISYPTAYLLTKLKHKQLWLL--LIILPTWINLLLKAYAFIGIFGTYGAANQFLEILGIgskQILFTDFSF 141
Cdd:PRK10971  67 AFVASIFNAVFGLLMAWILTRYRFPGRTLLdaLMDLPFALPTAVAGLTLASLFSVNGWYGEWLAKFDI---KVTYTWLGI 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 142 LFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLFMITRLIAGN-- 219
Cdd:PRK10971 144 AVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIAGNia 223

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489862341 220 ---RVITLGTAIEehfLVTQDWGMGSTIGVFLIIAMILIMFLTGSKKKRGARK 269
Cdd:PRK10971 224 wktEVTSLMIFVR---LQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRR 273
potC PRK09500
spermidine/putrescine ABC transporter membrane protein; Reviewed
 139-198 5.67e-05

spermidine/putrescine ABC transporter membrane protein; Reviewed


Pssm-ID: 236542 [Multi-domain]  Cd Length: 256  Bit Score: 43.43  E-value: 5.67e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341 139 FSFLFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSG 198
Cdd:PRK09500 128 WSLLFAHITFCLPFVVVTVYSRLKGFDVRMLEAAKDLGASEFTILRKIILPLALPAVAAG 187
modB PRK09421
molybdate ABC transporter permease subunit;
60-210 8.11e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 39.90  E-value: 8.11e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489862341  60 SFWYAFLITVFTLLISYPTAYLLTKLKH--KQLWLLLIILPTWINLLLKAYAFIGIFGTYGAANQFL-EILGIgskqilf 136
Cdd:PRK09421  14 SLKVSSVAVLFSLPFGILVAWLLARCRFpgKSLLDSLLHLPLVLPPVVTGYLLLISMGRRGFIGQWLyEWFGI------- 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489862341 137 tDFSF-----LFVSTYIFIPFMILPIFNAIEEINPTLIQASRDLGASSMTTFRRVIFPLTADGVKSGCQAVFIPALSLF 210
Cdd:PRK09421  87 -SFAFswrgaALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGEF 164
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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