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Conserved domains on  [gi|489864558|ref|WP_003768160|]
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MULTISPECIES: Na+/H+ antiporter subunit E [Listeria]

Protein Classification

Na+/H+ antiporter subunit E( domain architecture ID 10014032)

Na+/H+ antiporter subunit E is part of a Na+/H+ prokaryotic antiporter complex consists of seven subunits (MrpABCDEFG), which are involved in Na+ excretion

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-158 2.60e-57

Na+/H+ antiporter subunit E;


:

Pssm-ID: 237159  Cd Length: 158  Bit Score: 176.19  E-value: 2.60e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   1 MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL 80
Cdd:PRK12651   1 MAFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVL 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489864558  81 KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFH 158
Cdd:PRK12651  81 KPKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
 
Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-158 2.60e-57

Na+/H+ antiporter subunit E;


Pssm-ID: 237159  Cd Length: 158  Bit Score: 176.19  E-value: 2.60e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   1 MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL 80
Cdd:PRK12651   1 MAFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVL 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489864558  81 KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFH 158
Cdd:PRK12651  81 KPKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
4-157 2.73e-44

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 143.00  E-value: 2.73e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   4 QLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSR-FYLFRLFALVKLVFRFLHDLIVSTVHVSRIVLKK 82
Cdd:COG1863    7 HLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLLLFRRLPPPRlPYLRRPLRLLRLLLYFLWDIVVANIDVARRVLRP 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489864558  83 DMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVF 157
Cdd:COG1863   87 RLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRRTLYVHALDVDDPEALIEEIKGRYERRLLEIF 161
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 8-156 5.97e-41

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 134.13  E-value: 5.97e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558    8 NIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFA-LVKLVFRFLHDLIVSTVHVSRIVLKKDMNI 86
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLLPPRPPPRRPPLgLLRLLLYFLWEIVKANIQVARLVLRPKPPI 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   87 RPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEV 156
Cdd:pfam01899  81 RPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRRVLYVHVLDVDDEEAARREIKGRLERRLLEI 150
 
Name Accession Description Interval E-value
PRK12651 PRK12651
Na+/H+ antiporter subunit E;
1-158 2.60e-57

Na+/H+ antiporter subunit E;


Pssm-ID: 237159  Cd Length: 158  Bit Score: 176.19  E-value: 2.60e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   1 MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL 80
Cdd:PRK12651   1 MAFQLLLNIILAVLWLFLTGSFSLGNFIIGFILGLFVLFLFRRLLPARFYLRRIYKLIKLVPIFLKELIKANIDVAKIVL 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489864558  81 KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVFH 158
Cdd:PRK12651  81 KPKLNIEPGIVAVPTDLKTDWEITLLANLITLTPGTLTLDVSDDRKKLYIHAIDVKDKEEEIREIKDSFEKILLEVFE 158
MnhE COG1863
Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];
4-157 2.73e-44

Multisubunit Na+/H+ antiporter, MnhE subunit [Inorganic ion transport and metabolism];


Pssm-ID: 441468  Cd Length: 162  Bit Score: 143.00  E-value: 2.73e-44
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   4 QLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSR-FYLFRLFALVKLVFRFLHDLIVSTVHVSRIVLKK 82
Cdd:COG1863    7 HLLLSLLLALVWLLLSGSFSPGNLLLGLLLALLVLLLFRRLPPPRlPYLRRPLRLLRLLLYFLWDIVVANIDVARRVLRP 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489864558  83 DMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVF 157
Cdd:COG1863   87 RLPIRPGIVAVPLRLRSDLGITLLANSITLTPGTLTVDVDDDRRTLYVHALDVDDPEALIEEIKGRYERRLLEIF 161
PRK08965 PRK08965
putative monovalent cation/H+ antiporter subunit E; Reviewed
 1-157 2.98e-42

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181598  Cd Length: 162  Bit Score: 137.99  E-value: 2.98e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   1 MAFQLILNIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVL 80
Cdd:PRK08965   5 LLPQPLLSLWLALVWLLLNGSFSLGNLLLGLLLGLLIPLLLALLVPLEGRLRRPLALLRLLLVVLYDLVVSNIQVAWLIL 84

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489864558  81 KKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVF 157
Cdd:PRK08965  85 RPGPRPRPGFVAVPLRLRSDLALTLLANIITLTPGTVVVEISRDRRTLYVHVLDLDDPEALIREIKQRYERLLMEIF 161
MNHE pfam01899
Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.
 8-156 5.97e-41

Na+/H+ ion antiporter subunit; Subunit of a Na+/H+ Prokaryotic antiporter complex.


Pssm-ID: 460378  Cd Length: 150  Bit Score: 134.13  E-value: 5.97e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558    8 NIILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFA-LVKLVFRFLHDLIVSTVHVSRIVLKKDMNI 86
Cdd:pfam01899   1 NLLLAVVWLLLTGSFSPGNLLLGLLLGLLVLLLLRRLLPPRPPPRRPPLgLLRLLLYFLWEIVKANIQVARLVLRPKPPI 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   87 RPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEV 156
Cdd:pfam01899  81 RPGIVAVPLRLRSDLALTLLANSITLTPGTLVVDVDRDRRVLYVHVLDVDDEEAARREIKGRLERRLLEI 150
PRK08383 PRK08383
putative monovalent cation/H+ antiporter subunit E; Reviewed
 43-141 4.32e-16

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 181407  Cd Length: 168  Bit Score: 70.99  E-value: 4.32e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558  43 RFLGS-RFYLFRLFALVKLVFrflhDLIVSTVHVS-RIVLKKdmnIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSID 120
Cdd:PRK08383  55 RFLNPiRWLLFIAYAFGPLFW----GMVKANLDVAyRVITGK---IRPGIVKVPVDLENDAQYTILSNSITLTPGTLTIE 127

                         90       100
                 ....*....|....*....|.
gi 489864558 121 ISDDYKAIYVHSLHVPNIEEE 141
Cdd:PRK08383 128 ACPEEKALYVHWINVPEGLEK 148
PRK12652 PRK12652
monovalent cation/H+ antiporter subunit E;
65-159 3.11e-10

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237160 [Multi-domain]  Cd Length: 357  Bit Score: 57.07  E-value: 3.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558  65 LHDLIVSTVHVSRIVLKKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDykAIYVHSLhVPNIEEEIat 144
Cdd:PRK12652 235 LWEIVKANVAIAYVILHPSLPIDPTMVRVRAAVRSGLPLTTLANSITLTPGTLTVDVDDR--HLLVHSL-TPSAREDL-- 309

                         90
                 ....*....|....*
gi 489864558 145 IRKSYEGAIMEVFHG 159
Cdd:PRK12652 310 FDGGLERAVRFVFYG 324
PRK12654 PRK12654
monovalent cation/H+ antiporter subunit E;
58-127 5.64e-09

monovalent cation/H+ antiporter subunit E;


Pssm-ID: 237161  Cd Length: 151  Bit Score: 51.84  E-value: 5.64e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558  58 VKLVFRFLHDLIVSTVHVSRIVLKKDMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKA 127
Cdd:PRK12654   5 LKYAPWLIGQIFVAGFSLIKDAFKGDKNFNPVVVRYPLRVTKDWQITALAASITATPGTLSLGLREPRKP 74
PRK08382 PRK08382
putative monovalent cation/H+ antiporter subunit E; Reviewed
 9-157 2.99e-08

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 169415  Cd Length: 201  Bit Score: 50.56  E-value: 2.99e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   9 IILACLWMFLESSFSFATFIIGFIIGIFLLLFMRRFLG----------SRFYLFRLFALVKLVFRFLHDLIVSTVHVSRI 78
Cdd:PRK08382  40 LILLAFWVIISGDLSPRGLILGALTTLIIASYMRDFLTedirrsghllWKILYFALIYLPQYLIIMAFRLLESNLKVAKH 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558  79 VLKkdMNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISD--DYKAIYVHSLHVPNIEEEIA--TIRKSYEGAIM 154
Cdd:PRK08382 120 VIF--MDINPGIVKIKTDLHSDTGITILANSITLTPGTLTLDVVKklGETYLYVHWIDVETLNREKAgeKIKGDIEEWLK 197


                 ...
gi 489864558 155 EVF 157
Cdd:PRK08382 198 KIF 200
PRK12596 PRK12596
putative monovalent cation/H+ antiporter subunit E; Reviewed
 6-157 6.98e-07

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 105779  Cd Length: 171  Bit Score: 46.50  E-value: 6.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558   6 ILNIILACLWMFLeSSFSFATFIIGFIIGIFLLLFMRRFLGSRFYLFRLFALVKLVFRFLHDLIVSTVHVSRIVLKKDMN 85
Cdd:PRK12596   9 LLFVSLVLFWLLL-NSFTRAQFILGLVIAFGACRVMMALEPQKNHIRSPRMMIWLLYAASIDVLRSNIAVVRLILSPGRQ 87

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489864558  86 IRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHSLHVPNIEEEIATIRKSYEGAIMEVF 157
Cdd:PRK12596  88 RHPGFVVIPLELQNRTALAVLACMITASPGTAWVDYNAARGILTIHVLDLEDAETWRHLIKERYERPLIEIF 159
PRK06279 PRK06279
putative monovalent cation/H+ antiporter subunit E; Reviewed
 53-142 1.67e-06

putative monovalent cation/H+ antiporter subunit E; Reviewed


Pssm-ID: 180506 [Multi-domain]  Cd Length: 100  Bit Score: 44.27  E-value: 1.67e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489864558  53 RLFALVKLVFRFLHDLIVSTVHVSRIVLKKdmNIRPGIFRYDTTLETDWEVTMLALLITLTPGTLSIDISDDYKAIYVHS 132
Cdd:PRK06279   2 RLLYGIGYLIVLIKAIIEAWIDVVKRSLNG--KIDPEVIEIETEINRPVGQVLLANSITLTPGTLTIDLDSEERILKVAS 79

                         90
                 ....*....|
gi 489864558 133 LHvPNIEEEI 142
Cdd:PRK06279  80 IS-PRSRDDI 88
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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