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Conserved domains on  [gi|489925472|ref|WP_003828812|]
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MULTISPECIES: peroxide/acid stress response protein YhcN [Citrobacter]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-88 7.58e-46

peroxide/acid stress response protein YhcN;


:

Pssm-ID: 411360  Cd Length: 87  Bit Score: 141.71  E-value: 7.58e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472  1 MKIKTTIATLSLLSVLSFGASAAvTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRVTELREGAHW 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAA-QSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNW 79


                ....*...
gi 489925472 81 HATAELYK 88
Cdd:NF033776 80 HATAELYK 87
 
Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-88 7.58e-46

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 141.71  E-value: 7.58e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472  1 MKIKTTIATLSLLSVLSFGASAAvTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRVTELREGAHW 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAA-QSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNW 79


                ....*...
gi 489925472 81 HATAELYK 88
Cdd:NF033776 80 HATAELYK 87
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 35-87 1.57e-18

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 71.78  E-value: 1.57e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489925472  35 LQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRVTELRE--GAHWHATAELY 87
Cdd:pfam07338  1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADEpnGGNWHGTAELY 55
PRK14864 PRK14864
biofilm peroxide resistance protein BsmA;
1-88 1.14e-09

biofilm peroxide resistance protein BsmA;


Pssm-ID: 184866  Cd Length: 104  Bit Score: 50.43  E-value: 1.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472   1 MKIKTTIATLSLLSVLSFGASAAVTQV-------NSQE-----AQNLQSIGSVSVSQIGSsPMDMRQAIAAKAEKAGASS 68
Cdd:PRK14864   2 NMVMRRFASLLLTLLLSACSALQGTPQpapppadHAQEirraqTQGLQKMGTVSALVRGS-PDDAEREIQAKANAAGADY 80

                         90       100
                 ....*....|....*....|...
gi 489925472  69 YRVTELRE---GAHWHATAELYK 88
Cdd:PRK14864  81 YVIVMVDEtvvPGQWYSQAILYR 103
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-88 2.86e-06

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 43.16  E-value: 2.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472   1 MKIKTT-IATLSLLSVLSFGASAAVTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRV---TELRE 76
Cdd:NF040471   1 MKLKNTiLASALLLSLTALSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIqdtNDVNN 80

                         90
                 ....*....|..
gi 489925472  77 GAHWHATAELYK 88
Cdd:NF040471  81 SGNWRVTADLYH 92
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 24-88 4.85e-03

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 33.92  E-value: 4.85e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489925472  24 VTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSY---RVTELREGAHWHATAELYK 88
Cdd:NF040471 110 VKELPKDEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFfivRQVDANSGGNQSITAYIYK 177
 
Name Accession Description Interval E-value
stress_YhcN NF033776
peroxide/acid stress response protein YhcN;
1-88 7.58e-46

peroxide/acid stress response protein YhcN;


Pssm-ID: 411360  Cd Length: 87  Bit Score: 141.71  E-value: 7.58e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472  1 MKIKTTIATLSLLSVLSFGASAAvTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRVTELREGAHW 80
Cdd:NF033776  1 MKIKTTIAALSLLSVLSFGAFAA-QSVNAEQAQNLQSMGTISVSGVGGSPMDIRQALSQKADEQGASAYRVIEARNGGNW 79


                ....*...
gi 489925472 81 HATAELYK 88
Cdd:NF033776 80 HATAELYK 87
YdgH_BhsA-like pfam07338
YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around ...
 35-87 1.57e-18

YdgH/BhsA/McbA-like domain; This domain is found in several Enterobacterial proteins of around 90 residues in length, including E. coli YdgH, YhcN, BhsA and McbA, which play a role in stress response, biofilm formation and pathogenesis. BhsA (also known as ComC) reduces the permeability of the outer membrane to copper and may decrease biofilm formation by repressing cell-cell interaction and cell surface interaction. Members of this entry have one copy of this domain with the exception of YdgH, which has three copies. The function of this domain is unknown, however, it is suggested to be directly involved in host-pathogen interaction.


Pssm-ID: 429417 [Multi-domain]  Cd Length: 55  Bit Score: 71.78  E-value: 1.57e-18
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 489925472  35 LQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRVTELRE--GAHWHATAELY 87
Cdd:pfam07338  1 LQPIGTVSVSGVFGSPSDAEAALSKKADAKGAKSYRIISADEpnGGNWHGTAELY 55
PRK14864 PRK14864
biofilm peroxide resistance protein BsmA;
1-88 1.14e-09

biofilm peroxide resistance protein BsmA;


Pssm-ID: 184866  Cd Length: 104  Bit Score: 50.43  E-value: 1.14e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472   1 MKIKTTIATLSLLSVLSFGASAAVTQV-------NSQE-----AQNLQSIGSVSVSQIGSsPMDMRQAIAAKAEKAGASS 68
Cdd:PRK14864   2 NMVMRRFASLLLTLLLSACSALQGTPQpapppadHAQEirraqTQGLQKMGTVSALVRGS-PDDAEREIQAKANAAGADY 80

                         90       100
                 ....*....|....*....|...
gi 489925472  69 YRVTELRE---GAHWHATAELYK 88
Cdd:PRK14864  81 YVIVMVDEtvvPGQWYSQAILYR 103
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 1-88 2.86e-06

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 43.16  E-value: 2.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472   1 MKIKTT-IATLSLLSVLSFGASAAVTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSYRV---TELRE 76
Cdd:NF040471   1 MKLKNTiLASALLLSLTALSSAQAAQELTPEKAAALKPFDRITVTGRFNAIYEAADAVSRRADKMGAASFYIqdtNDVNN 80

                         90
                 ....*....|..
gi 489925472  77 GAHWHATAELYK 88
Cdd:NF040471  81 SGNWRVTADLYH 92
PRK10259 PRK10259
hypothetical protein; Provisional
 3-88 4.78e-05

hypothetical protein; Provisional


Pssm-ID: 137782  Cd Length: 86  Bit Score: 38.16  E-value: 4.78e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472  3 IKTTIATLSLlSVLSFGASAAvTQVNSQEAQNLQSIGSVSVSqiGSSPMDMRQA-IAAKAEKAGASSYRVTELREGAHWH 81
Cdd:PRK10259  4 INTVVAAMAL-STLSFGVFAA-EPVTASQAQNMNKIGVVSAD--GASTLDALEAkLAEKAAAAGASGYSITSATNNNKLS 79


                ....*..
gi 489925472 82 ATAELYK 88
Cdd:PRK10259 80 GTAVIYK 86
PRK09929 PRK09929
hypothetical protein; Provisional
 1-88 3.47e-03

hypothetical protein; Provisional


Pssm-ID: 182151  Cd Length: 91  Bit Score: 33.35  E-value: 3.47e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489925472  1 MKIKTTI--ATLSLLSVLSFGASAAVTQVNSQEAQNLQSIGSVSVSQiGSSPMDMRQAIAAKAEKAGASSYRVTELREGA 78
Cdd:PRK09929  1 MKIISKMllGALAFAVTNVYAAELMTKAEFEKVESQYEKIGTISTSN-EMSTADAKEDLIKKADEKGADVLVLTSGQTDN 79

                        90
                ....*....|
gi 489925472 79 HWHATAELYK 88
Cdd:PRK09929 80 KIHGTADIYK 89
ydgH_STM1478 NF040471
DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with ...
 24-88 4.85e-03

DUF1471 family protein YdgH; YdgH is the rare paralog in the DUF1471 family (PF07338) with three tandem copies of the DUF1471 domain instead of just one. Note that STM1478 from the Salmonella enterica model strain LT2 is also called SssB.


Pssm-ID: 439699 [Multi-domain]  Cd Length: 317  Bit Score: 33.92  E-value: 4.85e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489925472  24 VTQVNSQEAQNLQSIGSVSVSQIGSSPMDMRQAIAAKAEKAGASSY---RVTELREGAHWHATAELYK 88
Cdd:NF040471 110 VKELPKDEAYLLEPFDTVTVSGFFRSQPDVNDAIAKAAKEKGAASFfivRQVDANSGGNQSITAYIYK 177
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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