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Conserved domains on  [gi|489930858|ref|WP_003834178|]
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MULTISPECIES: FUSC family protein [Citrobacter]

Protein Classification

FUSC family protein( domain architecture ID 11441727)

FUSC family protein containing a fusaric acid resistance protein (FUSC_2) domain; may be involved in membrane transport

Gene Ontology:  GO:0055085|GO:0022857|GO:0005886
TCDB:  2.A.85

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.76e-40

Uncharacterized membrane protein YccC [Function unknown];


:

Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 142.84  E-value: 3.76e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  16 RHYRVVHGVRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPisFWGNVVPRAFERIGGTILGSVLGLVALRLELfSLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLALFP-QPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  96 LMLIWCAVAMFLCgWLALGKRPYQALLIGITLAVVVGAPAGD---MNTALWRGGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489930858 172 IQLAHCVTGYNRVYQAALSP-NLLEQPRLEKHLQQLLSDVVKMRGLIVPASKET-HIQKSIFEAIQTVNRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.76e-40

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 142.84  E-value: 3.76e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  16 RHYRVVHGVRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPisFWGNVVPRAFERIGGTILGSVLGLVALRLELfSLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLALFP-QPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  96 LMLIWCAVAMFLCgWLALGKRPYQALLIGITLAVVVGAPAGD---MNTALWRGGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489930858 172 IQLAHCVTGYNRVYQAALSP-NLLEQPRLEKHLQQLLSDVVKMRGLIVPASKET-HIQKSIFEAIQTVNRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 1.78e-13

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 66.50  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858   32 FTFLLVRLLNIPEGTWPLITLVVIMGPisFWGNVVPRAFERIGGTILGSVLGLVAlrLELFSLPLMLIWCAVAMFLCGwL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLL--LALLPGPLQLILVVALLGFLA-E 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 489930858  112 ALGKRPYQALLIGITLAVVVGA----PAGDMNTALWRGGDVILGSLLAMLF 158
Cdd:pfam13515  76 YLIGRNYALAQVFVTPLALLLAslagGGGPPELALLRILDTLIGALIALLV 126
 
Name Accession Description Interval E-value
YccC COG1289
Uncharacterized membrane protein YccC [Function unknown];
16-247 3.76e-40

Uncharacterized membrane protein YccC [Function unknown];


Pssm-ID: 440900 [Multi-domain]  Cd Length: 280  Bit Score: 142.84  E-value: 3.76e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  16 RHYRVVHGVRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPisFWGNVVPRAFERIGGTILGSVLGLVALRLELfSLP 95
Cdd:COG1289   43 DSPAFRHALRLALAALLALLIALLLGLPHPYWALLTVLIVLQP--SYGATLSRALQRILGTLLGALAGLLLLALFP-QPL 119
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  96 LMLIWCAVAMFLCgWLALGKRPYQALLIGITLAVVVGAPAGD---MNTALWRGGDVILGSLLAMLFTG-IWPQRAFIHWR 171
Cdd:COG1289  120 LLLLALALVLGLC-FFALLTRSYAFALAGITAAVVLLFALLGpgvFDVALARVLDTLIGILIALLVSYlLWPRWARRRLR 198
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489930858 172 IQLAHCVTGYNRVYQAALSP-NLLEQPRLEKHLQQLLSDVVKMRGLIVPASKET-HIQKSIFEAIQTVNRNLVCMLEL 247
Cdd:COG1289  199 ARLARALRANARYLRALLSQgDPADDLALRAARRRLAAALAALEALLQRALSEPpRGRRRELRALLALNHRLLSLLSA 276
FUSC_2 pfam13515
Fusaric acid resistance protein-like;
32-158 1.78e-13

Fusaric acid resistance protein-like;


Pssm-ID: 433273 [Multi-domain]  Cd Length: 126  Bit Score: 66.50  E-value: 1.78e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858   32 FTFLLVRLLNIPEGTWPLITLVVIMGPisFWGNVVPRAFERIGGTILGSVLGLVAlrLELFSLPLMLIWCAVAMFLCGwL 111
Cdd:pfam13515   1 LAALIAELLGLPRGYWAPIAAAIVLQP--TLGATLRRAVQRILGTVLGVLLGLLL--LALLPGPLQLILVVALLGFLA-E 75
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|.
gi 489930858  112 ALGKRPYQALLIGITLAVVVGA----PAGDMNTALWRGGDVILGSLLAMLF 158
Cdd:pfam13515  76 YLIGRNYALAQVFVTPLALLLAslagGGGPPELALLRILDTLIGALIALLV 126
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
20-224 1.39e-09

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 59.22  E-value: 1.39e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858   20 VVHGVRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPISfwGNVVPRAFERIGGTILGSVLGLVALRLELFSLPLMLI 99
Cdd:pfam04632   1 WLFALKTFLAAMLALYIALRLELPQPYWAMTTVFIVSQPLS--GAVLSKSFYRLLGTLVGAAAAVLLVALFVQAPLLFLL 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  100 WCAVAMFLCGWLAL---GKRPYQALLIGITLAVV----VGAPAGDMNTALWRGGDVILGSLLAMLFTGI-WPQRAfihwR 171
Cdd:pfam04632  79 ALALWIGLCLALSLldrNFRSYAFVLAGYTAAIIglpaVADPEAIFDIAVARVSEISLGILCAALVSALvFPRSV----G 154
                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 489930858  172 IQLAHCVTG-YNRVYQAALSPNL--LEQPRLEKHLQQLLSDVVKMRGLIVPASKET 224
Cdd:pfam04632 155 PALRARLRArLRDALRLAAAALAgaPGAEAFEAARLRLAADILALEALRSHAAFES 210
YgaE COG4129
Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];
24-190 3.56e-09

Uncharacterized membrane protein YgaE, UPF0421/DUF939 family [Function unknown];


Pssm-ID: 443305 [Multi-domain]  Cd Length: 197  Bit Score: 55.77  E-value: 3.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858  24 VRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPiSFWGNVVpRAFERIGGTILGSVLGLVALRLELFSLPLMLIWCAV 103
Cdd:COG4129   15 LKTALAAALAWLIAELLGLPYPFFAAIAAVLCLQP-TVGRSLR-RALERILGVLIGALVGVLFFLLLGYGPWQLGLAVLL 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858 104 AMFLCGWLalgKRPYQALLIGITLAVVV--GAPAGDMNTALWRGGDVILGSLLAMLFT-GIWPQRAFIHWRIQLAHCVTG 180
Cdd:COG4129   93 AILLAVLL---KLGEGIVLAAVTALLVLllGSPDDSLGYALNRLLDTLIGVGVALLVNlLLLPPDPERRLRRAAAELLEE 169
                        170
                 ....*....|
gi 489930858 181 YNRVYQAALS 190
Cdd:COG4129  170 LADILRELLR 179
FUSC pfam04632
Fusaric acid resistance protein family; This family includes a conserved region found in two ...
23-171 1.47e-03

Fusaric acid resistance protein family; This family includes a conserved region found in two proteins associated with fusaric acid resistance, from Burkholderia cepacia and Klebsiella oxytoca. These proteins are likely to be membrane transporter proteins.


Pssm-ID: 428044 [Multi-domain]  Cd Length: 655  Bit Score: 40.35  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858   23 GVRIALAFLFTFLLVRLLNIPEGTWPLITLVVIMGPISFWGNVVPRAFERIGGTILGSVLGLVALrleLFSLPL-----M 97
Cdd:pfam04632 349 GLRAALAILLAGAFWIATGWPSGATAVLLAAIVCSLFATLDNPAPAARQFLRGTLLAALAALLYL---FFVLPHvdgfpL 425
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489930858   98 LIWCAVAMFLCGWLALGKRPY--QALLIGITLAVVVG---APAGDMNTALWRGGDVILGSLLA-MLFTGIWPQRAFIHWR 171
Cdd:pfam04632 426 LCLVLAPPLLLGGLLLARPRTagIGLGLAVFFALLLApqnPYTYDFAAFLNSALALLLGVLLAaVVFRLIRPVSAEWLAR 505
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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