|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
1-384 |
0e+00 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 783.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 1 MNSLCSDAVIVNEtnDNWTRMGKELLSQADIRINGSRAWDIQLHHTGFFKRVLQQGSLGLGESYMEGWWDCERLDILFCK 80
Cdd:PRK11705 1 MSSSCIEEVSVPD--DNWYRIANELLARAGITINGSRPWDIQVHNPRFFKRVLQEGSLGLGESYMDGWWDCDRLDEFFSR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 81 ILKAKLDQQMPGNLKDILRIASARLFNLQSRSRAWIVGKEHYDIGNDLFALMLDPHMQYSCGYWKDATTLNDAQNAKLKM 160
Cdd:PRK11705 79 VLRAGLDEKLPHHLKDTLRILRARLFNLQSKKRAWIVGKEHYDLGNDLFEAMLDPRMQYSCGYWKDADTLEEAQEAKLDL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 161 ICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGLDVNILLQDYRDLNKHYDRIVSVGMF 240
Cdd:PRK11705 159 ICRKLQLKPGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCAGLPVEIRLQDYRDLNGQFDRIVSVGMF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 241 EHVGPKNYDTYFSIADRCLKPDGLFLLHTIGSNKKGMSVDPWINKYIFPNGCLPAISHIAEASESRFVMEDWHNFGSDYD 320
Cdd:PRK11705 239 EHVGPKNYRTYFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASEGLFVMEDWHNFGADYD 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489942924 321 KTLMAWHERFNQAWPELSSRYSATFRRMFNYYLCACAGAFRARDIELWQVLFS-RGVEGGIRVYR 384
Cdd:PRK11705 319 RTLMAWHENFEAAWPELADNYSERFYRMWRYYLLSCAGAFRARDIQLWQVVFSpRGVEGGYRVPR 383
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
110-370 |
9.21e-128 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 368.19 E-value: 9.21e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 110 SRSRAWIVGKEHYDIGNDLFALMLDPHMQYSCGYWKDA-TTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAA 188
Cdd:pfam02353 1 SKTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFERPdMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 189 RHYGVAVEGVTISKEQQKMAQQRCEGLD----VNILLQDYRDLNKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGL 264
Cdd:pfam02353 81 ERYDVNVVGLTLSKNQYKLARKRVAAEGlarkVEVLLQDYRDFDEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 265 FLLHTIGSNKKGMSVD-----PWINKYIFPNGCLPAISHIAE-ASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPELS 338
Cdd:pfam02353 161 MLLHTITGLHPDETSErglplKFIDKYIFPGGELPSISMIVEsSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKDEAI 240
|
250 260 270
....*....|....*....|....*....|..
gi 489942924 339 SRYSATFRRMFNYYLCACAGAFRARDIELWQV 370
Cdd:pfam02353 241 ALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
120-269 |
1.42e-78 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 238.68 E-value: 1.42e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 120 EHYDIGNDLFALMLDPHMQYSCGYWKD-ATTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGV 198
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDpDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489942924 199 TISKEQQKMAQQRCE--GLD--VNILLQDYRDLNK--HYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLLHT 269
Cdd:COG2230 81 TLSPEQLEYARERAAeaGLAdrVEVRLADYRDLPAdgQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
53-379 |
3.53e-74 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 235.66 E-value: 3.53e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 53 LQQGSLG-LGESYMEGwwdceRLDILfckilkakldqqmpGNLKDILRIASARlfnlqsrSRAwIVGKE----------- 120
Cdd:NF040703 47 LTHPSLDlLGSAYVEG-----RLDLE--------------GPIMEVIRVGDEL-------SQA-LLGDDdeappertahd 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 121 ----------HYDIGNDLFALMLDPHMQYSCGYWKDAT-TLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAAR 189
Cdd:NF040703 100 katdaaaisyHYDLSNDFYALWLDPDMVYSCAYFETGTeDLAQAQQAKLRHLCRKLRLQPGERLLDVGCGWGGLARFAAR 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 190 HYGVAVEGVTISKEQQKMAQQRC--EGLD--VNILLQDYRDL--NKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDG 263
Cdd:NF040703 180 EFGVEVFGITLSKEQLKLARERVaaEGLQdrVQLELLDYRDLpqDGRFDKVVSVGMFEHVGHANLPLYCQRLFGAVRPGG 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 264 LFLLHTIGSNKK-----GMSVDPWINKYIFPNGCLPAISHI-AEASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPEL 337
Cdd:NF040703 260 LVMNHGITARHTdgrpvGRGAGEFIGRYVFPHGELPHLATItASISEAGLEVVDVESLRLHYARTLEHWSARLEARLDEA 339
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 489942924 338 SSRYSATFRRMFNYYLCACAGAFRARDIELWQVLFSRGVEGG 379
Cdd:NF040703 340 ARLVPERALRIWRLYLAGCAYGFARGWINLHQILAVKPLADG 381
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
121-370 |
2.93e-59 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 193.45 E-value: 2.93e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 121 HYDIGNDLFALMLDPHMQYSCGYW-KDATTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVT 199
Cdd:NF040660 11 HYDLSDDFFALFLDPTQTYSCAYFeRDDMTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNVVGLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 200 ISKEQQKMAQQRCEGLDVN----ILLQDYRDLNKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLLHTIGS--- 272
Cdd:NF040660 91 LSKNQAAHVQQVLDEIDTPrsrrVLLQGWEEFDEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHTITGlhr 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 273 ---NKKGMSVDPWINKY-------IFPNGCLPAISHIAE-ASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPELSSRY 341
Cdd:NF040660 171 kemHERGLPLTMELARFikfivteIFPGGRLPSIEMVVEhAEKAGFTVTRVQSLQPHYARTLDLWADALQAHKDEAIAIQ 250
|
250 260
....*....|....*....|....*....
gi 489942924 342 SATFRRMFNYYLCACAGAFRARDIELWQV 370
Cdd:NF040660 251 SEEVYERYMKYLTGCAKLFRDGYIDVNQF 279
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
172-268 |
1.64e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 63.22 E-value: 1.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 172 RLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGL---DVNILLQDYRDL----NKHYDRIVSVGMFEHVg 244
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALladNVEVLKGDAEELppeaDESFDVIISDPPLHHL- 79
|
90 100
....*....|....*....|....
gi 489942924 245 PKNYDTYFSIADRCLKPDGLFLLH 268
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVLT 103
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
172-273 |
1.06e-07 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 52.03 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 172 RLLDIGCGWG-GLAEYAARHYGVAVEGVTISKEQQKMAQQRCE--GLDVNILLQdYRDLNK-----HYDRIVSVGMFEHV 243
Cdd:smart00828 2 RVLDFGCGYGsDLIDLAERHPHLQLHGYTISPEQAEVGRERIRalGLQGRIRIF-YRDSAKdpfpdTYDLVFGFEVIHHI 80
|
90 100 110
....*....|....*....|....*....|
gi 489942924 244 gpKNYDTYFSIADRCLKPDGLFLLHTIGSN 273
Cdd:smart00828 81 --KDKMDLFSNISRHLKDGGHLVLADFIAN 108
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK11705 |
PRK11705 |
cyclopropane fatty acyl phospholipid synthase; |
1-384 |
0e+00 |
|
cyclopropane fatty acyl phospholipid synthase;
Pssm-ID: 183282 Cd Length: 383 Bit Score: 783.65 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 1 MNSLCSDAVIVNEtnDNWTRMGKELLSQADIRINGSRAWDIQLHHTGFFKRVLQQGSLGLGESYMEGWWDCERLDILFCK 80
Cdd:PRK11705 1 MSSSCIEEVSVPD--DNWYRIANELLARAGITINGSRPWDIQVHNPRFFKRVLQEGSLGLGESYMDGWWDCDRLDEFFSR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 81 ILKAKLDQQMPGNLKDILRIASARLFNLQSRSRAWIVGKEHYDIGNDLFALMLDPHMQYSCGYWKDATTLNDAQNAKLKM 160
Cdd:PRK11705 79 VLRAGLDEKLPHHLKDTLRILRARLFNLQSKKRAWIVGKEHYDLGNDLFEAMLDPRMQYSCGYWKDADTLEEAQEAKLDL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 161 ICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGLDVNILLQDYRDLNKHYDRIVSVGMF 240
Cdd:PRK11705 159 ICRKLQLKPGMRVLDIGCGWGGLARYAAEHYGVSVVGVTISAEQQKLAQERCAGLPVEIRLQDYRDLNGQFDRIVSVGMF 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 241 EHVGPKNYDTYFSIADRCLKPDGLFLLHTIGSNKKGMSVDPWINKYIFPNGCLPAISHIAEASESRFVMEDWHNFGSDYD 320
Cdd:PRK11705 239 EHVGPKNYRTYFEVVRRCLKPDGLFLLHTIGSNKTDTNVDPWINKYIFPNGCLPSVRQIAQASEGLFVMEDWHNFGADYD 318
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489942924 321 KTLMAWHERFNQAWPELSSRYSATFRRMFNYYLCACAGAFRARDIELWQVLFS-RGVEGGIRVYR 384
Cdd:PRK11705 319 RTLMAWHENFEAAWPELADNYSERFYRMWRYYLLSCAGAFRARDIQLWQVVFSpRGVEGGYRVPR 383
|
|
| CMAS |
pfam02353 |
Mycolic acid cyclopropane synthetase; This family consist of ... |
110-370 |
9.21e-128 |
|
Mycolic acid cyclopropane synthetase; This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
Pssm-ID: 396777 [Multi-domain] Cd Length: 272 Bit Score: 368.19 E-value: 9.21e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 110 SRSRAWIVGKEHYDIGNDLFALMLDPHMQYSCGYWKDA-TTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAA 188
Cdd:pfam02353 1 SKTRDAENIQAHYDLSNDFFALFLDPTMTYSCAYFERPdMTLEEAQQAKLDLILDKLGLKPGMTLLDIGCGWGGLMRRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 189 RHYGVAVEGVTISKEQQKMAQQRCEGLD----VNILLQDYRDLNKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGL 264
Cdd:pfam02353 81 ERYDVNVVGLTLSKNQYKLARKRVAAEGlarkVEVLLQDYRDFDEPFDRIVSVGMFEHVGHENYDTFFKKLYNLLPPGGL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 265 FLLHTIGSNKKGMSVD-----PWINKYIFPNGCLPAISHIAE-ASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPELS 338
Cdd:pfam02353 161 MLLHTITGLHPDETSErglplKFIDKYIFPGGELPSISMIVEsSSEAGFTVEDVESLRPHYAKTLDLWAENLQANKDEAI 240
|
250 260 270
....*....|....*....|....*....|..
gi 489942924 339 SRYSATFRRMFNYYLCACAGAFRARDIELWQV 370
Cdd:pfam02353 241 ALQSEEFYRMWMLYLTGCAVAFRIGYIDVHQF 272
|
|
| Cfa |
COG2230 |
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ... |
120-269 |
1.42e-78 |
|
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];
Pssm-ID: 441831 [Multi-domain] Cd Length: 158 Bit Score: 238.68 E-value: 1.42e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 120 EHYDIGNDLFALMLDPHMQYSCGYWKD-ATTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGV 198
Cdd:COG2230 1 HHYDLGNDFYRLFLDPTMTYSCAYFEDpDDTLEEAQEAKLDLILRKLGLKPGMRVLDIGCGWGGLALYLARRYGVRVTGV 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489942924 199 TISKEQQKMAQQRCE--GLD--VNILLQDYRDLNK--HYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLLHT 269
Cdd:COG2230 81 TLSPEQLEYARERAAeaGLAdrVEVRLADYRDLPAdgQFDAIVSIGMFEHVGPENYPAYFAKVARLLKPGGRLLLHT 157
|
|
| cyclopro_CfaB |
NF040703 |
C17 cyclopropane fatty acid synthase CfaB; |
53-379 |
3.53e-74 |
|
C17 cyclopropane fatty acid synthase CfaB;
Pssm-ID: 468667 [Multi-domain] Cd Length: 393 Bit Score: 235.66 E-value: 3.53e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 53 LQQGSLG-LGESYMEGwwdceRLDILfckilkakldqqmpGNLKDILRIASARlfnlqsrSRAwIVGKE----------- 120
Cdd:NF040703 47 LTHPSLDlLGSAYVEG-----RLDLE--------------GPIMEVIRVGDEL-------SQA-LLGDDdeappertahd 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 121 ----------HYDIGNDLFALMLDPHMQYSCGYWKDAT-TLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAAR 189
Cdd:NF040703 100 katdaaaisyHYDLSNDFYALWLDPDMVYSCAYFETGTeDLAQAQQAKLRHLCRKLRLQPGERLLDVGCGWGGLARFAAR 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 190 HYGVAVEGVTISKEQQKMAQQRC--EGLD--VNILLQDYRDL--NKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDG 263
Cdd:NF040703 180 EFGVEVFGITLSKEQLKLARERVaaEGLQdrVQLELLDYRDLpqDGRFDKVVSVGMFEHVGHANLPLYCQRLFGAVRPGG 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 264 LFLLHTIGSNKK-----GMSVDPWINKYIFPNGCLPAISHI-AEASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPEL 337
Cdd:NF040703 260 LVMNHGITARHTdgrpvGRGAGEFIGRYVFPHGELPHLATItASISEAGLEVVDVESLRLHYARTLEHWSARLEARLDEA 339
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 489942924 338 SSRYSATFRRMFNYYLCACAGAFRARDIELWQVLFSRGVEGG 379
Cdd:NF040703 340 ARLVPERALRIWRLYLAGCAYGFARGWINLHQILAVKPLADG 381
|
|
| mycolic_MTase |
NF040660 |
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include ... |
121-370 |
2.93e-59 |
|
cyclopropane mycolic acid synthase family methyltransferase; Members of this family include tailoring enzymes that make site-specific modifications to mycolic acid precursor molecules. These include Mycobacterium tuberculosis enzymes MmaA1-MmaA4, CmaA1-CmaA2, and PcaA. The family also includes UmaA, reported to be the lone member of this family not involved in mycolic acid biosynthesis. No members of this family are found in species that lack mycolic acids. This model excludes two more distantly related paralogs, Rv0447c (UfaA1 ) and Rv3720, that are also encoded in the Mycobacterium tuberculosis H37Rv genome.
Pssm-ID: 468626 Cd Length: 283 Bit Score: 193.45 E-value: 2.93e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 121 HYDIGNDLFALMLDPHMQYSCGYW-KDATTLNDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVT 199
Cdd:NF040660 11 HYDLSDDFFALFLDPTQTYSCAYFeRDDMTLEEAQIAKIDLALGKLNLEPGMTLLDIGCGWGATMRRAVEKYDVNVVGLT 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 200 ISKEQQKMAQQRCEGLDVN----ILLQDYRDLNKHYDRIVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLLHTIGS--- 272
Cdd:NF040660 91 LSKNQAAHVQQVLDEIDTPrsrrVLLQGWEEFDEPVDRIVSIGAFEHFGHERYDDFFKRAYNILPADGRMLLHTITGlhr 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 273 ---NKKGMSVDPWINKY-------IFPNGCLPAISHIAE-ASESRFVMEDWHNFGSDYDKTLMAWHERFNQAWPELSSRY 341
Cdd:NF040660 171 kemHERGLPLTMELARFikfivteIFPGGRLPSIEMVVEhAEKAGFTVTRVQSLQPHYARTLDLWADALQAHKDEAIAIQ 250
|
250 260
....*....|....*....|....*....
gi 489942924 342 SATFRRMFNYYLCACAGAFRARDIELWQV 370
Cdd:NF040660 251 SEEVYERYMKYLTGCAKLFRDGYIDVNQF 279
|
|
| Methyltransf_25 |
pfam13649 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
174-263 |
1.76e-21 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 463945 [Multi-domain] Cd Length: 96 Bit Score: 88.00 E-value: 1.76e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 174 LDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCE--GLDVNILLQDYRDL---NKHYDRIVSVGMFEHVGPKNY 248
Cdd:pfam13649 2 LDLGCGTGRLTLALARRGGARVTGVDLSPEMLERARERAAeaGLNVEFVQGDAEDLpfpDGSFDLVVSSGVLHHLPDPDL 81
|
90
....*....|....*
gi 489942924 249 DTYFSIADRCLKPDG 263
Cdd:pfam13649 82 EAALREIARVLKPGG 96
|
|
| UbiG |
COG2227 |
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ... |
167-270 |
3.64e-20 |
|
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis
Pssm-ID: 441829 [Multi-domain] Cd Length: 126 Bit Score: 85.45 E-value: 3.64e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 167 LKPGMRLLDIGCGWGGLAEYAARHyGVAVEGVTISKEQQKMAQQRCEGLDVNILLQDYRDL---NKHYDRIVSVGMFEHV 243
Cdd:COG2227 22 LPAGGRVLDVGCGTGRLALALARR-GADVTGVDISPEALEIARERAAELNVDFVQGDLEDLpleDGSFDLVICSEVLEHL 100
|
90 100
....*....|....*....|....*..
gi 489942924 244 gpKNYDTYFSIADRCLKPDGLFLLHTI 270
Cdd:COG2227 101 --PDPAALLRELARLLKPGGLLLLSTP 125
|
|
| SmtA |
COG0500 |
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, ... |
161-267 |
3.04e-17 |
|
SAM-dependent methyltransferase [Secondary metabolites biosynthesis, transport and catabolism, General function prediction only];
Pssm-ID: 440266 [Multi-domain] Cd Length: 199 Bit Score: 79.19 E-value: 3.04e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 161 ICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGLD---VNILLQDYRDLNK----HYDR 233
Cdd:COG0500 18 LALLERLPKGGRVLDLGCGTGRNLLALAARFGGRVIGIDLSPEAIALARARAAKAGlgnVEFLVADLAELDPlpaeSFDL 97
|
90 100 110
....*....|....*....|....*....|....
gi 489942924 234 IVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLL 267
Cdd:COG0500 98 VVAFGVLHHLPPEEREALLRELARALKPGGVLLL 131
|
|
| UbiE |
COG2226 |
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ... |
161-271 |
3.36e-17 |
|
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis
Pssm-ID: 441828 [Multi-domain] Cd Length: 143 Bit Score: 77.73 E-value: 3.36e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 161 ICEKLQLKPGMRLLDIGCGWGGLAEYAARHyGVAVEGVTISKEQQKMAQQRCE--GLDVNILLQDYRDL---NKHYDRIV 235
Cdd:COG2226 14 LLAALGLRPGARVLDLGCGTGRLALALAER-GARVTGVDISPEMLELARERAAeaGLNVEFVVGDAEDLpfpDGSFDLVI 92
|
90 100 110
....*....|....*....|....*....|....*.
gi 489942924 236 SVGMFEHVgpKNYDTYFSIADRCLKPDGLFLLHTIG 271
Cdd:COG2226 93 SSFVLHHL--PDPERALAEIARVLKPGGRLVVVDFS 126
|
|
| Methyltransf_11 |
pfam08241 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
174-267 |
1.95e-15 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 462406 [Multi-domain] Cd Length: 94 Bit Score: 71.16 E-value: 1.95e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 174 LDIGCGWGGLAEYAARhYGVAVEGVTISKEQQKMAQQRCEGLDVNILLQDYRDL---NKHYDRIVSVGMFEHVgpKNYDT 250
Cdd:pfam08241 1 LDVGCGTGLLTELLAR-LGARVTGVDISPEMLELAREKAPREGLTFVVGDAEDLpfpDNSFDLVLSSEVLHHV--EDPER 77
|
90
....*....|....*..
gi 489942924 251 YFSIADRCLKPDGLFLL 267
Cdd:pfam08241 78 ALREIARVLKPGGILII 94
|
|
| AdoMet_MTases |
cd02440 |
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; ... |
172-268 |
1.64e-12 |
|
S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). There are at least five structurally distinct families of AdoMet-MTases, class I being the largest and most diverse. Within this class enzymes can be classified by different substrate specificities (small molecules, lipids, nucleic acids, etc.) and different target atoms for methylation (nitrogen, oxygen, carbon, sulfur, etc.).
Pssm-ID: 100107 [Multi-domain] Cd Length: 107 Bit Score: 63.22 E-value: 1.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 172 RLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGL---DVNILLQDYRDL----NKHYDRIVSVGMFEHVg 244
Cdd:cd02440 1 RVLDLGCGTGALALALASGPGARVTGVDISPVALELARKAAAALladNVEVLKGDAEELppeaDESFDVIISDPPLHHL- 79
|
90 100
....*....|....*....|....
gi 489942924 245 PKNYDTYFSIADRCLKPDGLFLLH 268
Cdd:cd02440 80 VEDLARFLEEARRLLKPGGVLVLT 103
|
|
| COG4976 |
COG4976 |
Predicted methyltransferase, contains TPR repeat [General function prediction only]; |
127-267 |
2.10e-12 |
|
Predicted methyltransferase, contains TPR repeat [General function prediction only];
Pssm-ID: 444001 [Multi-domain] Cd Length: 181 Bit Score: 65.02 E-value: 2.10e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 127 DLFALMLDPHMQYSCGYwkdattlnDAQNAKLKMICEKLQLKPGMRLLDIGCGWGGLAEyAARHYGVAVEGVTISKEQQK 206
Cdd:COG4976 12 DQYADSYDAALVEDLGY--------EAPALLAEELLARLPPGPFGRVLDLGCGTGLLGE-ALRPRGYRLTGVDLSEEMLA 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489942924 207 MAQQRceGLDVNILLQDYRDL---NKHYDRIVSVGMFEHVGpkNYDTYFSIADRCLKPDGLFLL 267
Cdd:COG4976 83 KAREK--GVYDRLLVADLADLaepDGRFDLIVAADVLTYLG--DLAAVFAGVARALKPGGLFIF 142
|
|
| Tam |
COG4106 |
Trans-aconitate methyltransferase [Energy production and conversion]; |
169-267 |
4.12e-11 |
|
Trans-aconitate methyltransferase [Energy production and conversion];
Pssm-ID: 443282 [Multi-domain] Cd Length: 100 Bit Score: 59.07 E-value: 4.12e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 169 PGMRLLDIGCGWGGLAEY-AARHYGVAVEGVTISKEQQKMAQQRCEGLDVniLLQDYRDL--NKHYDRIVSVGMFEHVgp 245
Cdd:COG4106 1 PPRRVLDLGCGTGRLTALlAERFPGARVTGVDLSPEMLARARARLPNVRF--VVADLRDLdpPEPFDLVVSNAALHWL-- 76
|
90 100
....*....|....*....|..
gi 489942924 246 KNYDTYFSIADRCLKPDGLFLL 267
Cdd:COG4106 77 PDHAALLARLAAALAPGGVLAV 98
|
|
| Methyltransf_23 |
pfam13489 |
Methyltransferase domain; This family appears to be a methyltransferase domain. |
167-273 |
3.58e-10 |
|
Methyltransferase domain; This family appears to be a methyltransferase domain.
Pssm-ID: 404385 [Multi-domain] Cd Length: 162 Bit Score: 58.21 E-value: 3.58e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 167 LKPGMRLLDIGCGWGGLAEYaARHYGVAVEGVTISKEQQKMA--QQRCEGLDVnillQDYRDLNKHYDRIVSVGMFEHVg 244
Cdd:pfam13489 20 LPSPGRVLDFGCGTGIFLRL-LRAQGFSVTGVDPSPIAIERAllNVRFDQFDE----QEAAVPAGKFDVIVAREVLEHV- 93
|
90 100
....*....|....*....|....*....
gi 489942924 245 pKNYDTYFSIADRCLKPDGLFLLHTIGSN 273
Cdd:pfam13489 94 -PDPPALLRQIAALLKPGGLLLLSTPLAS 121
|
|
| PLN02244 |
PLN02244 |
tocopherol O-methyltransferase |
122-209 |
8.73e-08 |
|
tocopherol O-methyltransferase
Pssm-ID: 215135 [Multi-domain] Cd Length: 340 Bit Score: 53.59 E-value: 8.73e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 122 YDIGNDLFALMLDPHMQYscGYWKDATTLNDAQNAKLKMICEKL---------QLKPgMRLLDIGCGWGGLAEYAARHYG 192
Cdd:PLN02244 65 YDESSGVWEDVWGEHMHH--GYYDPGASRGDHRQAQIRMIEESLawagvpdddEKRP-KRIVDVGCGIGGSSRYLARKYG 141
|
90
....*....|....*..
gi 489942924 193 VAVEGVTISKEQQKMAQ 209
Cdd:PLN02244 142 ANVKGITLSPVQAARAN 158
|
|
| PKS_MT |
smart00828 |
Methyltransferase in polyketide synthase (PKS) enzymes; |
172-273 |
1.06e-07 |
|
Methyltransferase in polyketide synthase (PKS) enzymes;
Pssm-ID: 214839 [Multi-domain] Cd Length: 224 Bit Score: 52.03 E-value: 1.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 172 RLLDIGCGWG-GLAEYAARHYGVAVEGVTISKEQQKMAQQRCE--GLDVNILLQdYRDLNK-----HYDRIVSVGMFEHV 243
Cdd:smart00828 2 RVLDFGCGYGsDLIDLAERHPHLQLHGYTISPEQAEVGRERIRalGLQGRIRIF-YRDSAKdpfpdTYDLVFGFEVIHHI 80
|
90 100 110
....*....|....*....|....*....|
gi 489942924 244 gpKNYDTYFSIADRCLKPDGLFLLHTIGSN 273
Cdd:smart00828 81 --KDKMDLFSNISRHLKDGGHLVLADFIAN 108
|
|
| PTZ00098 |
PTZ00098 |
phosphoethanolamine N-methyltransferase; Provisional |
159-275 |
7.24e-07 |
|
phosphoethanolamine N-methyltransferase; Provisional
Pssm-ID: 173391 [Multi-domain] Cd Length: 263 Bit Score: 49.97 E-value: 7.24e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 159 KMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGLD------VNILLQDYRDLNkhYD 232
Cdd:PTZ00098 42 TKILSDIELNENSKVLDIGSGLGGGCKYINEKYGAHVHGVDICEKMVNIAKLRNSDKNkiefeaNDILKKDFPENT--FD 119
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 489942924 233 RIVSVGMFEHVGPKNYDTYFSIADRCLKPDGLFLLHTIGSNKK 275
Cdd:PTZ00098 120 MIYSRDAILHLSYADKKKLFEKCYKWLKPNGILLITDYCADKI 162
|
|
| ubiE |
PRK00216 |
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol ... |
121-219 |
1.95e-06 |
|
bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE;
Pssm-ID: 234689 [Multi-domain] Cd Length: 239 Bit Score: 48.61 E-value: 1.95e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 121 HYDIGNDLFALMLDPhmqyscgYWKDATtlndaqnaklkmiCEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVA--VEGV 198
Cdd:PRK00216 23 KYDLMNDLLSFGLHR-------VWRRKT-------------IKWLGVRPGDKVLDLACGTGDLAIALAKAVGKTgeVVGL 82
|
90 100
....*....|....*....|...
gi 489942924 199 TISKEQQKMAQQRC--EGLDVNI 219
Cdd:PRK00216 83 DFSEGMLAVGREKLrdLGLSGNV 105
|
|
| Methyltransf_12 |
pfam08242 |
Methyltransferase domain; Members of this family are SAM dependent methyltransferases. |
174-265 |
4.12e-06 |
|
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
Pssm-ID: 400515 [Multi-domain] Cd Length: 98 Bit Score: 45.05 E-value: 4.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 174 LDIGCGWGGLAEYAARHY-GVAVEGVTISKEQQKMAQQR-CEGLDVNILLQDYRDLN------KHYDRIVSVGMFEHVGP 245
Cdd:pfam08242 1 LEIGCGTGTLLRALLEALpGLEYTGLDISPAALEAARERlAALGLLNAVRVELFQLDlgeldpGSFDVVVASNVLHHLAD 80
|
90 100
....*....|....*....|
gi 489942924 246 KnyDTYFSIADRCLKPDGLF 265
Cdd:pfam08242 81 P--RAVLRNIRRLLKPGGVL 98
|
|
| PLN02336 |
PLN02336 |
phosphoethanolamine N-methyltransferase |
159-215 |
1.19e-05 |
|
phosphoethanolamine N-methyltransferase
Pssm-ID: 177970 [Multi-domain] Cd Length: 475 Bit Score: 47.05 E-value: 1.19e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 489942924 159 KMICEKLQLKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQQKMAQQRCEGL 215
Cdd:PLN02336 256 KEFVDKLDLKPGQKVLDVGCGIGGGDFYMAENFDVHVVGIDLSVNMISFALERAIGR 312
|
|
| TrmN6 |
COG4123 |
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) ... |
167-265 |
7.09e-05 |
|
tRNA1(Val) A37 N6-methylase TrmN6 [Translation, ribosomal structure and biogenesis]; tRNA1(Val) A37 N6-methylase TrmN6 is part of the Pathway/BioSystem: tRNA modification
Pssm-ID: 443299 [Multi-domain] Cd Length: 238 Bit Score: 43.59 E-value: 7.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 167 LKPGMRLLDIGCGWGGLAEY-AARHYGVAVEGVTISKEQQKMAQQRCE--GLD--VNILLQDYRDLNKH-----YDRIVS 236
Cdd:COG4123 35 VKKGGRVLDLGTGTGVIALMlAQRSPGARITGVEIQPEAAELARRNVAlnGLEdrITVIHGDLKEFAAElppgsFDLVVS 114
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 489942924 237 ------VGMFE-----------HVGPKNYDTYFSIADRCLKPDGLF 265
Cdd:COG4123 115 nppyfkAGSGRkspdearaiarHEDALTLEDLIRAAARLLKPGGRF 160
|
|
| FtsJ |
pfam01728 |
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal ... |
167-267 |
1.01e-04 |
|
FtsJ-like methyltransferase; This family consists of FtsJ from various bacterial and archaeal sources FtsJ is a methyltransferase, but actually has no effect on cell division. FtsJ's substrate is the 23S rRNA. The 1.5 A crystal structure of FtsJ in complex with its cofactor S-adenosylmethionine revealed that FtsJ has a methyltransferase fold. This family also includes the N terminus of flaviviral NS5 protein. It has been hypothesized that the N-terminal domain of NS5 is a methyltransferase involved in viral RNA capping.
Pssm-ID: 426399 Cd Length: 179 Bit Score: 42.58 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 167 LKPGMRLLDIGCGWGGLAEYAARHYGVAVEGVTISKEQ--QKMAQQRCEGLDVNIL-LQDYRDLNKHYDRIVSV----GM 239
Cdd:pfam01728 19 LKPGKTVLDLGAAPGGWSQVALQRGAGKVVGVDLGPMQlwKPRNDPGVTFIQGDIRdPETLDLLEELLGRKVDLvlsdGS 98
|
90 100 110
....*....|....*....|....*....|....*..
gi 489942924 240 FEHVGPKNYDTY---------FSIADRCLKPDGLFLL 267
Cdd:pfam01728 99 PFISGNKVLDHLrsldlvkaaLEVALELLRKGGNFVC 135
|
|
| PCMT |
pfam01135 |
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT); |
160-216 |
1.44e-04 |
|
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
Pssm-ID: 395902 [Multi-domain] Cd Length: 205 Bit Score: 42.36 E-value: 1.44e-04
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 160 MICEKLQLKPGMRLLDIGCGWGGLAEYAAR---HYGVAVeGVTISKEQQKMAQQRCEGLD 216
Cdd:pfam01135 64 MMLELLELKPGMRVLEIGSGSGYLTACFARmvgEVGRVV-SIEHIPELVEIARRNLEKLG 122
|
|
| PRK08317 |
PRK08317 |
hypothetical protein; Provisional |
163-263 |
2.38e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 181382 [Multi-domain] Cd Length: 241 Bit Score: 42.23 E-value: 2.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 163 EKLQLKPGMRLLDIGCGWGGLAEYAARHYGVA--VEGVTISKEQQKMAQQRCEGLDVNILLQ-------DYRDLNkhYDR 233
Cdd:PRK08317 13 ELLAVQPGDRVLDVGCGPGNDARELARRVGPEgrVVGIDRSEAMLALAKERAAGLGPNVEFVrgdadglPFPDGS--FDA 90
|
90 100 110
....*....|....*....|....*....|
gi 489942924 234 IVSVGMFEHVgpKNYDTYFSIADRCLKPDG 263
Cdd:PRK08317 91 VRSDRVLQHL--EDPARALAEIARVLRPGG 118
|
|
| SpeE |
COG0421 |
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism]; |
176-272 |
5.83e-04 |
|
Spermidine synthase (polyamine aminopropyltransferase) [Amino acid transport and metabolism];
Pssm-ID: 440190 [Multi-domain] Cd Length: 195 Bit Score: 40.58 E-value: 5.83e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 176 IGCGWGGLAEYAARHYGVA-VEGVTISKEQQKMAQQ----RCEGLD---VNILLQD---Y-RDLNKHYDrIVSVGMFEHV 243
Cdd:COG0421 44 IGGGDGGLARELLKHPPVErVDVVEIDPEVVELAREyfplLAPAFDdprLRVVIGDgraFlREAEESYD-VIIVDLTDPV 122
|
90 100 110
....*....|....*....|....*....|..
gi 489942924 244 GP-KNYDT--YFSIADRCLKPDGLFLLHTIGS 272
Cdd:COG0421 123 GPaEGLFTreFYEDCRRALKPGGVLVVNLGSP 154
|
|
| RsmC |
COG2813 |
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA ... |
163-267 |
9.60e-04 |
|
16S rRNA G1207 methylase RsmC [Translation, ribosomal structure and biogenesis]; 16S rRNA G1207 methylase RsmC is part of the Pathway/BioSystem: 16S rRNA modification
Pssm-ID: 442062 [Multi-domain] Cd Length: 191 Bit Score: 39.79 E-value: 9.60e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 163 EKLQLKPGMRLLDIGCGWGGLAEYAARHYGVA-VEGVTISKEQQKMAQQRCE--GLD-VNILLQDYRD--LNKHYDRIVS 236
Cdd:COG2813 43 EHLPEPLGGRVLDLGCGYGVIGLALAKRNPEArVTLVDVNARAVELARANAAanGLEnVEVLWSDGLSgvPDGSFDLILS 122
|
90 100 110
....*....|....*....|....*....|....*
gi 489942924 237 VGMFeHVGPK-NYDTYFSI---ADRCLKPDGLFLL 267
Cdd:COG2813 123 NPPF-HAGRAvDKEVAHALiadAARHLRPGGELWL 156
|
|
| Methyltransf_31 |
pfam13847 |
Methyltransferase domain; This family appears to have methyltransferase activity. |
167-267 |
9.62e-04 |
|
Methyltransferase domain; This family appears to have methyltransferase activity.
Pssm-ID: 463998 [Multi-domain] Cd Length: 150 Bit Score: 39.32 E-value: 9.62e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 167 LKPGMRLLDIGCGWGGLAEYAARHYGVAVE--GVTISKEQQKMAQQRCE--GLD-VNILLQDYRDLNKHY-----DRIVS 236
Cdd:pfam13847 1 IDKGMRVLDLGCGTGHLSFELAEELGPNAEvvGIDISEEAIEKARENAQklGFDnVEFEQGDIEELPELLeddkfDVVIS 80
|
90 100 110
....*....|....*....|....*....|.
gi 489942924 237 VGMFEHVGpkNYDTYFSIADRCLKPDGLFLL 267
Cdd:pfam13847 81 NCVLNHIP--DPDKVLQEILRVLKPGGRLII 109
|
|
| Pcm |
COG2518 |
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ... |
160-243 |
2.22e-03 |
|
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 442008 [Multi-domain] Cd Length: 197 Bit Score: 38.92 E-value: 2.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 160 MICEKLQLKPGMRLLDIGCGwGG-----LAEYAARHYgvAVEgvtISKEQQKMAQQRCEGLDV-NILLqDYRDLNK---- 229
Cdd:COG2518 57 RMLEALDLKPGDRVLEIGTG-SGyqaavLARLAGRVY--SVE---RDPELAERARERLAALGYdNVTV-RVGDGALgwpe 129
|
90
....*....|....*.
gi 489942924 230 --HYDRIVSVGMFEHV 243
Cdd:COG2518 130 haPFDRIIVTAAAPEV 145
|
|
| RlmE |
COG0293 |
23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and ... |
157-200 |
4.21e-03 |
|
23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ [Translation, ribosomal structure and biogenesis]; 23S rRNA U2552 (ribose-2'-O)-methylase RlmE/FtsJ is part of the Pathway/BioSystem: 23S rRNA modification
Pssm-ID: 440062 [Multi-domain] Cd Length: 208 Bit Score: 38.13 E-value: 4.21e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 489942924 157 KLKMICEKLQL-KPGMRLLDIGCGWGGLAEYAARHYG-----VAV--------EGVTI 200
Cdd:COG0293 37 KLLEIDEKDKLiKPGMRVVDLGAAPGGWSQVAAKRVGgkgrvIALdllpmepiPGVEF 94
|
|
| pcm |
PRK00312 |
protein-L-isoaspartate(D-aspartate) O-methyltransferase; |
159-235 |
6.71e-03 |
|
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
Pssm-ID: 178974 [Multi-domain] Cd Length: 212 Bit Score: 37.49 E-value: 6.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489942924 159 KMIcEKLQLKPGMRLLDIGCGWGG----LAEYAARHYgvavegvTIS--KEQQKMAQQRCEGLDV-NILLqdyrdlnKH- 230
Cdd:PRK00312 69 RMT-ELLELKPGDRVLEIGTGSGYqaavLAHLVRRVF-------SVEriKTLQWEAKRRLKQLGLhNVSV-------RHg 133
|
90
....*....|....*.
gi 489942924 231 -----------YDRIV 235
Cdd:PRK00312 134 dgwkgwpayapFDRIL 149
|
|
| |
