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Conserved domains on  [gi|489945573|ref|WP_003848880|]
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MULTISPECIES: bile acid:sodium symporter family protein [Pantoea]

Protein Classification

bile acid:sodium symporter family protein( domain architecture ID 10612733)

bile acid:sodium symporter (BASS) family protein, similar to fungal olute carrier RCH1, an influx transporter that may be involved in cytosolic calcium homeostasis

Gene Ontology:  GO:0015293|GO:0006810|GO:0016020
PubMed:  23506869|23177985
TCDB:  2.A.28

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SBF_like pfam13593
SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane ...
7-317 1.73e-105

SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.


:

Pssm-ID: 433336  Cd Length: 313  Bit Score: 311.43  E-value: 1.73e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573    7 DPMMVKLIITVLLASFLPAKGIYVDVF--SYLATAAIALLFFMHGAKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLL 84
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIraEYVITYGVALIFFLSGLRLSTEELLAGLRNWRLHLFVQLFTFVLFPLLGLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573   85 LVWWHPVDVGPEIYTGFIYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDIhSSAPSDGLEQ 164
Cdd:pfam13593  81 LSSLLPAALPPELLIGFLLLAALPTTVSSSVAMTSQAGGNVAAAVCNASIGNLLGVFLTPALVGLLLGG-GGAGIDYGAV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  165 IGKIMLQLMVPFILGHLSRRWIGGWVEKHRSLIGKTDQTSILLVVYSAFSEAVVNGIWHRVGLTTLLWIVAGSIILLTAV 244
Cdd:pfam13593 160 LKKLGLQVLLPLVLGQLLRPWFPKWTKRHKKLLKKVDSGVILLIVYTSFSTAFVQGAFHSVSHSILLVIFNVGLYLLAVV 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489945573  245 LIINLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFPA-STVGIIVLPLMIFHQVQLMVCSFIAGRYKK 317
Cdd:pfam13593 240 LGATWFLARLLGFSREDEIAILFCGSKKSLALGVPLASVLFGGnPQLGLILLPLLLYHQIQLMVCSVLAPRLAR 313
 
Name Accession Description Interval E-value
SBF_like pfam13593
SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane ...
7-317 1.73e-105

SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.


Pssm-ID: 433336  Cd Length: 313  Bit Score: 311.43  E-value: 1.73e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573    7 DPMMVKLIITVLLASFLPAKGIYVDVF--SYLATAAIALLFFMHGAKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLL 84
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIraEYVITYGVALIFFLSGLRLSTEELLAGLRNWRLHLFVQLFTFVLFPLLGLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573   85 LVWWHPVDVGPEIYTGFIYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDIhSSAPSDGLEQ 164
Cdd:pfam13593  81 LSSLLPAALPPELLIGFLLLAALPTTVSSSVAMTSQAGGNVAAAVCNASIGNLLGVFLTPALVGLLLGG-GGAGIDYGAV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  165 IGKIMLQLMVPFILGHLSRRWIGGWVEKHRSLIGKTDQTSILLVVYSAFSEAVVNGIWHRVGLTTLLWIVAGSIILLTAV 244
Cdd:pfam13593 160 LKKLGLQVLLPLVLGQLLRPWFPKWTKRHKKLLKKVDSGVILLIVYTSFSTAFVQGAFHSVSHSILLVIFNVGLYLLAVV 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489945573  245 LIINLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFPA-STVGIIVLPLMIFHQVQLMVCSFIAGRYKK 317
Cdd:pfam13593 240 LGATWFLARLLGFSREDEIAILFCGSKKSLALGVPLASVLFGGnPQLGLILLPLLLYHQIQLMVCSVLAPRLAR 313
YfeH COG0385
Predicted Na+-dependent transporter YfeH [General function prediction only];
7-317 4.88e-69

Predicted Na+-dependent transporter YfeH [General function prediction only];


Pssm-ID: 440154  Cd Length: 294  Bit Score: 217.71  E-value: 4.88e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573   7 DPMMVKLIITVLLASFLPAkgiyvdVFSYLATAAIALLFFMHGAKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLLLV 86
Cdd:COG0385    1 DWFLLLLLLAVVLALLLPA------AFEPLLPLLLALIMFGMGLTLSPEDFKRVLRRPRLVLLGLLAQFVLMPLLALALA 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  87 WWHPVDvgPEIYTGFIYLCILPATVQSAIaFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDiHSSAPSDGLEQIG 166
Cdd:COG0385   75 LLFGLP--PELALGLLLLAACPGGVASNV-FTSLARGNVALSVSLTAVSTLLAPFLTPLLVALLLG-LQGVEVDPLDMIL 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573 167 KIMLQLMVPFILGHLSRRWIGGWVEKHRSLIGKTDQTSILLVVYSAFSEAVVNgiwhrvGLTTLLWIVAGSIILLTAVLI 246
Cdd:COG0385  151 SLLLIVLLPLVLGMLLRRLLPKWAERLKKPLPLVSRLAILLIVYAAFAANVDN------LLSVGLLVLLAVLLLNALGLL 224
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489945573 247 INLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFPAstvGIIVLPLMIFHQVQLMVCSFIAGRYKK 317
Cdd:COG0385  225 LGYLLARLLGLDRADRITIAFEVGMKNLGLALVLATTLFPG---PLAALPAALYHLWQLIVGALLARRWAR 292
 
Name Accession Description Interval E-value
SBF_like pfam13593
SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane ...
7-317 1.73e-105

SBF-like CPA transporter family (DUF4137); These family members are 7TM putative membrane transporter proteins. The family is similar to the SBF family of bile-acid symporters, pfam01758.


Pssm-ID: 433336  Cd Length: 313  Bit Score: 311.43  E-value: 1.73e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573    7 DPMMVKLIITVLLASFLPAKGIYVDVF--SYLATAAIALLFFMHGAKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLL 84
Cdd:pfam13593   1 QWFLLGLVLAILLASLLPVFGAAGGPIraEYVITYGVALIFFLSGLRLSTEELLAGLRNWRLHLFVQLFTFVLFPLLGLG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573   85 LVWWHPVDVGPEIYTGFIYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDIhSSAPSDGLEQ 164
Cdd:pfam13593  81 LSSLLPAALPPELLIGFLLLAALPTTVSSSVAMTSQAGGNVAAAVCNASIGNLLGVFLTPALVGLLLGG-GGAGIDYGAV 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  165 IGKIMLQLMVPFILGHLSRRWIGGWVEKHRSLIGKTDQTSILLVVYSAFSEAVVNGIWHRVGLTTLLWIVAGSIILLTAV 244
Cdd:pfam13593 160 LKKLGLQVLLPLVLGQLLRPWFPKWTKRHKKLLKKVDSGVILLIVYTSFSTAFVQGAFHSVSHSILLVIFNVGLYLLAVV 239
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 489945573  245 LIINLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFPA-STVGIIVLPLMIFHQVQLMVCSFIAGRYKK 317
Cdd:pfam13593 240 LGATWFLARLLGFSREDEIAILFCGSKKSLALGVPLASVLFGGnPQLGLILLPLLLYHQIQLMVCSVLAPRLAR 313
YfeH COG0385
Predicted Na+-dependent transporter YfeH [General function prediction only];
7-317 4.88e-69

Predicted Na+-dependent transporter YfeH [General function prediction only];


Pssm-ID: 440154  Cd Length: 294  Bit Score: 217.71  E-value: 4.88e-69
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573   7 DPMMVKLIITVLLASFLPAkgiyvdVFSYLATAAIALLFFMHGAKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLLLV 86
Cdd:COG0385    1 DWFLLLLLLAVVLALLLPA------AFEPLLPLLLALIMFGMGLTLSPEDFKRVLRRPRLVLLGLLAQFVLMPLLALALA 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  87 WWHPVDvgPEIYTGFIYLCILPATVQSAIaFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDiHSSAPSDGLEQIG 166
Cdd:COG0385   75 LLFGLP--PELALGLLLLAACPGGVASNV-FTSLARGNVALSVSLTAVSTLLAPFLTPLLVALLLG-LQGVEVDPLDMIL 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573 167 KIMLQLMVPFILGHLSRRWIGGWVEKHRSLIGKTDQTSILLVVYSAFSEAVVNgiwhrvGLTTLLWIVAGSIILLTAVLI 246
Cdd:COG0385  151 SLLLIVLLPLVLGMLLRRLLPKWAERLKKPLPLVSRLAILLIVYAAFAANVDN------LLSVGLLVLLAVLLLNALGLL 224
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 489945573 247 INLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFPAstvGIIVLPLMIFHQVQLMVCSFIAGRYKK 317
Cdd:COG0385  225 LGYLLARLLGLDRADRITIAFEVGMKNLGLALVLATTLFPG---PLAALPAALYHLWQLIVGALLARRWAR 292
ACR3 COG0798
Arsenite efflux pump ArsB, ACR3 family [Inorganic ion transport and metabolism];
14-300 2.13e-03

Arsenite efflux pump ArsB, ACR3 family [Inorganic ion transport and metabolism];


Pssm-ID: 440561  Cd Length: 335  Bit Score: 39.34  E-value: 2.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  14 IITVLLASFLPAKGIYVDVFSYLATA---AIALLFFMHG--AKLSREKIIAGSSHWQLHLWIMFSTFVLFPALGLLLVWW 88
Cdd:COG0798   21 AAGLLLGYLFPGVFQALASLEVATVNipiAILLWLMIYPmmAKVDFEELGKVFRNPKGLGLTLVINWLIKPFLMFALAWL 100
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573  89 HpVDVGPEIYTGFIYLCILPATVQsAIAFTSMAGGNVAAAVCSASASSLLGVFISPLLVNLVMDIhSSAPSDGLEQIGKI 168
Cdd:COG0798  101 F-LPDAPEYIAGLILLGLAPCTAM-VIVWTGLAKGDVEYALVLVALNLLLQVLLFPPYVWLLLGV-SDVTVPWGTLALSV 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489945573 169 MLQLMVPFILGHLSRRWI---GGWVEKHRSLIGKTDQTSI---LLVVYSAFS---EAVVNGIWHrvglttLLWIVAGSII 239
Cdd:COG0798  178 LLYVVIPLAAGFLTRRLLlrrKGREWFEERFLPKLSPISLlglLLTIVLLFAlqgETILENPLD------ILLIAIPLLI 251
                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489945573 240 LLTAVLIINLLASRLFRFKRADEIVVLFCGSKKSLANGVPMANILFP-------ASTVGIIV-LPLMIF 300
Cdd:COG0798  252 QFAINFALSYLLGRLLGLPYEDAAPLAFTGASNNFELALAVAIALFGlnsgaalATVVGPLIeVPVMLS 320
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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