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Conserved domains on  [gi|489956364|ref|WP_003859671|]
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MULTISPECIES: YecA family protein [Enterobacteriaceae]

Protein Classification

YecA family protein( domain architecture ID 11484693)

YecA family protein similar to Escherichia coli uncharacterized protein YecA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10396 PRK10396
hypothetical protein; Provisional
 1-222 1.24e-147

hypothetical protein; Provisional


:

Pssm-ID: 236680 [Multi-domain]  Cd Length: 221  Bit Score: 409.91  E-value: 1.24e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   1 MAEGPLNESEMAWLEETLISYGHDDaSVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYIPRWKNDREMNRFIDLC 80
Cdd:PRK10396   1 MKTGPLNESELEWLDDILTKYGTDH-AILDVAELDGLLTAVLSSPREIEPAQWLVAIWGGADYVPRWASEKEMTRFMDLA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364  81 FKHMNDIAERLSEYPDQFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALTDWSSLPEALEADLAVIALHGTEENSEKLDAL 160
Cdd:PRK10396  80 FQHMNDTAERLNEYPEQFEPLFGLREVDGQELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFELLEKM 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489956364 161 TEEEYMASIESIQPAALRLYNYWVANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCCLH 222
Cdd:PRK10396 160 SPEAFEESVDAIRPAALALHAYWMAHPQEKAVQQPIKAEEKVGRNDPCPCGSGKKFKQCCLH 221
 
Name Accession Description Interval E-value
PRK10396 PRK10396
hypothetical protein; Provisional
 1-222 1.24e-147

hypothetical protein; Provisional


Pssm-ID: 236680 [Multi-domain]  Cd Length: 221  Bit Score: 409.91  E-value: 1.24e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   1 MAEGPLNESEMAWLEETLISYGHDDaSVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYIPRWKNDREMNRFIDLC 80
Cdd:PRK10396   1 MKTGPLNESELEWLDDILTKYGTDH-AILDVAELDGLLTAVLSSPREIEPAQWLVAIWGGADYVPRWASEKEMTRFMDLA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364  81 FKHMNDIAERLSEYPDQFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALTDWSSLPEALEADLAVIALHGTEENSEKLDAL 160
Cdd:PRK10396  80 FQHMNDTAERLNEYPEQFEPLFGLREVDGQELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFELLEKM 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489956364 161 TEEEYMASIESIQPAALRLYNYWVANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCCLH 222
Cdd:PRK10396 160 SPEAFEESVDAIRPAALALHAYWMAHPQEKAVQQPIKAEEKVGRNDPCPCGSGKKFKQCCLH 221
ygfB_yecA TIGR02292
yecA family protein; This family resembles pfam03695 (version pfam03695.3), uncharacterised ...
 13-160 1.85e-35

yecA family protein; This family resembles pfam03695 (version pfam03695.3), uncharacterised protein family UPF0149, but is broader in scope and includes additional proteins. It includes E. coli proteins YgfB and YecA. The function of this family of proteins is unknown. The crystal structure is known for the member from Haemophilus influenzae (Ygfb, HI0817). [Unknown function, General]


Pssm-ID: 274071  Cd Length: 150  Bit Score: 122.48  E-value: 1.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   13 WLEETLISYGhDDASVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYIPrWKNDREMNRFIDLCFKHMNDIAERLS 92
Cdd:TIGR02292   3 RLSDFLDALE-LDGECMNLEELDGFLTALLSGPEVLKPQEWLPLVWGGENQAA-FDSEEQATRIIDLIVQHYNQIAAQLS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   93 EYPDQFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALT--DWSSLPEALEADLAVIALHGTEENSEKLDAL 160
Cdd:TIGR02292  81 DGPEKFPPLLPLDEDDGEEDQRGDDWANGFLLGIDLRpdDWATLMDDEETAELVDPIMDLGGLYDEEENM 150
UPF0149 pfam03695
Uncharacterized protein family (UPF0149); The protein in this family are about 190 amino acids ...
 13-183 1.09e-31

Uncharacterized protein family (UPF0149); The protein in this family are about 190 amino acids long. The function of these proteins is unknown.


Pssm-ID: 427445  Cd Length: 170  Bit Score: 113.58  E-value: 1.09e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   13 WLEETLISYGHDDaSVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYiprwKNDREMNRFIDLCFKHMNDIAERLS 92
Cdd:pfam03695   2 ELDQLLDSAGLPE-DPMDLAELHGFLTGLLCGPVPIPPEEWLPAVWGLAEE----ASDEEGERFLALLMRLYNEIAAQLA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   93 EYPDqFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALT--DWSS-----LPEALEaDLAVIAlhGTEENSEKLDALTEEEY 165
Cdd:pfam03695  77 DDPD-FEFELLPDDPLDDRAEPLFEWCEGFLLGLGLAgeDWRDasdeeLAEALD-DLAALA--QLEADEEDDDEESEEAL 152

                         170
                  ....*....|....*...
gi 489956364  166 MASIESIQPAALRLYNYW 183
Cdd:pfam03695 153 EELIEYVRVAVLLLYEEW 170
YecA COG3318
Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C ...
 183-222 3.93e-14

Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif [Function unknown];


Pssm-ID: 442547 [Multi-domain]  Cd Length: 45  Bit Score: 64.15  E-value: 3.93e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 489956364 183 WVANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCCLH 222
Cdd:COG3318    5 LACGPDLWALAIPRRAEPKVGRNDPCPCGSGKKYKKCCGA 44
 
Name Accession Description Interval E-value
PRK10396 PRK10396
hypothetical protein; Provisional
 1-222 1.24e-147

hypothetical protein; Provisional


Pssm-ID: 236680 [Multi-domain]  Cd Length: 221  Bit Score: 409.91  E-value: 1.24e-147
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   1 MAEGPLNESEMAWLEETLISYGHDDaSVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYIPRWKNDREMNRFIDLC 80
Cdd:PRK10396   1 MKTGPLNESELEWLDDILTKYGTDH-AILDVAELDGLLTAVLSSPREIEPAQWLVAIWGGADYVPRWASEKEMTRFMDLA 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364  81 FKHMNDIAERLSEYPDQFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALTDWSSLPEALEADLAVIALHGTEENSEKLDAL 160
Cdd:PRK10396  80 FQHMNDTAERLNEYPEQFEPLFGLREVDGQELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFELLEKM 159

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489956364 161 TEEEYMASIESIQPAALRLYNYWVANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCCLH 222
Cdd:PRK10396 160 SPEAFEESVDAIRPAALALHAYWMAHPQEKAVQQPIKAEEKVGRNDPCPCGSGKKFKQCCLH 221
ygfB_yecA TIGR02292
yecA family protein; This family resembles pfam03695 (version pfam03695.3), uncharacterised ...
 13-160 1.85e-35

yecA family protein; This family resembles pfam03695 (version pfam03695.3), uncharacterised protein family UPF0149, but is broader in scope and includes additional proteins. It includes E. coli proteins YgfB and YecA. The function of this family of proteins is unknown. The crystal structure is known for the member from Haemophilus influenzae (Ygfb, HI0817). [Unknown function, General]


Pssm-ID: 274071  Cd Length: 150  Bit Score: 122.48  E-value: 1.85e-35
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   13 WLEETLISYGhDDASVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYIPrWKNDREMNRFIDLCFKHMNDIAERLS 92
Cdd:TIGR02292   3 RLSDFLDALE-LDGECMNLEELDGFLTALLSGPEVLKPQEWLPLVWGGENQAA-FDSEEQATRIIDLIVQHYNQIAAQLS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   93 EYPDQFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALT--DWSSLPEALEADLAVIALHGTEENSEKLDAL 160
Cdd:TIGR02292  81 DGPEKFPPLLPLDEDDGEEDQRGDDWANGFLLGIDLRpdDWATLMDDEETAELVDPIMDLGGLYDEEENM 150
UPF0149 pfam03695
Uncharacterized protein family (UPF0149); The protein in this family are about 190 amino acids ...
 13-183 1.09e-31

Uncharacterized protein family (UPF0149); The protein in this family are about 190 amino acids long. The function of these proteins is unknown.


Pssm-ID: 427445  Cd Length: 170  Bit Score: 113.58  E-value: 1.09e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   13 WLEETLISYGHDDaSVIDVSELDGMLTAVLSGPVVVEPDTWLVAVWGGEKYiprwKNDREMNRFIDLCFKHMNDIAERLS 92
Cdd:pfam03695   2 ELDQLLDSAGLPE-DPMDLAELHGFLTGLLCGPVPIPPEEWLPAVWGLAEE----ASDEEGERFLALLMRLYNEIAAQLA 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364   93 EYPDqFEPLFGYNDVDGQSYTVVEEWCYGYMRGVALT--DWSS-----LPEALEaDLAVIAlhGTEENSEKLDALTEEEY 165
Cdd:pfam03695  77 DDPD-FEFELLPDDPLDDRAEPLFEWCEGFLLGLGLAgeDWRDasdeeLAEALD-DLAALA--QLEADEEDDDEESEEAL 152

                         170
                  ....*....|....*...
gi 489956364  166 MASIESIQPAALRLYNYW 183
Cdd:pfam03695 153 EELIEYVRVAVLLLYEEW 170
YecA COG3318
Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C ...
 183-222 3.93e-14

Uncharacterized conserved protein YecA, UPF0149 family, contains C-terminal Zn-binding SEC-C motif [Function unknown];


Pssm-ID: 442547 [Multi-domain]  Cd Length: 45  Bit Score: 64.15  E-value: 3.93e-14
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|
gi 489956364 183 WVANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCCLH 222
Cdd:COG3318    5 LACGPDLWALAIPRRAEPKVGRNDPCPCGSGKKYKKCCGA 44
SecA COG0653
Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, ...
 184-220 1.07e-13

Preprotein translocase subunit SecA (ATPase, RNA helicase) [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440418 [Multi-domain]  Cd Length: 876  Bit Score: 69.29  E-value: 1.07e-13
                         10        20        30
                 ....*....|....*....|....*....|....*..
gi 489956364 184 VANPQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCC 220
Cdd:COG0653  836 AGEEEEEAPKQPVRKGPKVGRNDPCPCGSGKKYKHCH 872
PRK05590 PRK05590
hypothetical protein; Provisional
 194-220 5.16e-13

hypothetical protein; Provisional


Pssm-ID: 235521  Cd Length: 166  Bit Score: 64.61  E-value: 5.16e-13
                         10        20
                 ....*....|....*....|....*..
gi 489956364 194 KPIVNGSKVGRNDPCPCGSGKKFKSCC 220
Cdd:PRK05590 137 KTVVNENKVGRNDPCPCGSGKKYKKCC 163
PRK02250 PRK02250
hypothetical protein; Provisional
 187-220 1.44e-10

hypothetical protein; Provisional


Pssm-ID: 179393 [Multi-domain]  Cd Length: 166  Bit Score: 57.96  E-value: 1.44e-10
                         10        20        30
                 ....*....|....*....|....*....|....
gi 489956364 187 PQQPEAKKPIVNGSKVGRNDPCPCGSGKKFKSCC 220
Cdd:PRK02250 132 PEQDPRLNQSVSSLKQGRNDPCICGSGKKFKKCC 165
PRK01617 PRK01617
hypothetical protein; Provisional
 201-220 3.64e-10

hypothetical protein; Provisional


Pssm-ID: 234966  Cd Length: 154  Bit Score: 56.58  E-value: 3.64e-10
                         10        20
                 ....*....|....*....|
gi 489956364 201 KVGRNDPCPCGSGKKFKSCC 220
Cdd:PRK01617 133 QFGRNDPCPCGSGKKFKKCC 152
SWIM_PBPRA1643 TIGR04102
SWIM/SEC-C metal-binding motif protein, PBPRA1643 family; Members of this protein family have ...
 150-220 1.33e-09

SWIM/SEC-C metal-binding motif protein, PBPRA1643 family; Members of this protein family have a SWIM, or SEC-C, domain (see pfam02810), a 21-amino acid putative Zn-binding domain that is shared with SecA, plant MuDR transposases, etc. This small protein family of unknown function occurs primarily in marine bacteria.


Pssm-ID: 200353 [Multi-domain]  Cd Length: 108  Bit Score: 53.85  E-value: 1.33e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489956364  150 TEENSEKLDA-LTEEEYMASIEsiqpaalrlynywvANPQQPE---------AK-KPIVNGSKVGRNDPCPCGSGKKFKS 218
Cdd:TIGR04102  40 SEERKAEVEAiLAEHELFANIE--------------VNADQEEniveldgllNKpKTTTFEKTPNRNDPCPCGSGKKYKK 105


                  ..
gi 489956364  219 CC 220
Cdd:TIGR04102 106 CC 107
SEC-C pfam02810
SEC-C motif; The SEC-C motif found in the C-terminus of the SecA protein, in the middle of ...
 204-222 1.34e-09

SEC-C motif; The SEC-C motif found in the C-terminus of the SecA protein, in the middle of some SWI2 ATPases and also solo in several proteins. The motif is predicted to chelate zinc with the CXC and C[HC] pairs that constitute the most conserved feature of the motif. It is predicted to be a potential nucleic acid binding domain.


Pssm-ID: 460704 [Multi-domain]  Cd Length: 19  Bit Score: 51.71  E-value: 1.34e-09
                          10
                  ....*....|....*....
gi 489956364  204 RNDPCPCGSGKKFKSCCLH 222
Cdd:pfam02810   1 RNDPCPCGSGKKYKKCCGP 19
PRK00183 PRK00183
hypothetical protein; Provisional
 201-220 2.88e-08

hypothetical protein; Provisional


Pssm-ID: 166842  Cd Length: 157  Bit Score: 51.34  E-value: 2.88e-08
                         10        20
                 ....*....|....*....|
gi 489956364 201 KVGRNDPCPCGSGKKFKSCC 220
Cdd:PRK00183 133 KAGRNDPCPCGSGQKFKKCC 152
secA PRK12901
preprotein translocase subunit SecA; Reviewed
 161-220 7.74e-06

preprotein translocase subunit SecA; Reviewed


Pssm-ID: 237256 [Multi-domain]  Cd Length: 1112  Bit Score: 46.17  E-value: 7.74e-06
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489956364  161 TEEEYMASIESIQPAALRLYNYWVANPQQPEAkkPIVNGSKVGRNDPCPC-----GSGKKFKSCC 220
Cdd:PRK12901 1036 LDPKYRTQKEEIQDSDQRAAASRDTGAQVKET--PVRVEKKIGRNDPVPCqnvdgGSGKKYKFKH 1098
PRK12904 PRK12904
preprotein translocase subunit SecA; Reviewed
 206-220 2.12e-05

preprotein translocase subunit SecA; Reviewed


Pssm-ID: 237259 [Multi-domain]  Cd Length: 830  Bit Score: 44.69  E-value: 2.12e-05
                         10
                 ....*....|....*
gi 489956364 206 DPCPCGSGKKFKSCC 220
Cdd:PRK12904 812 DPCPCGSGKKYKHCH 826
YchJ COG3012
Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains [Function ...
 203-220 9.43e-05

Uncharacterized conserved protein YchJ, contains N- and C-terminal SEC-C domains [Function unknown];


Pssm-ID: 442249  Cd Length: 144  Bit Score: 40.98  E-value: 9.43e-05
                         10
                 ....*....|....*...
gi 489956364 203 GRNDPCPCGSGKKFKSCC 220
Cdd:COG3012    1 PSNSPCPCGSGKPYADCC 18
PRK01752 PRK01752
YchJ family protein;
207-220 1.28e-03

YchJ family protein;


Pssm-ID: 179332  Cd Length: 156  Bit Score: 38.23  E-value: 1.28e-03
                         10
                 ....*....|....
gi 489956364 207 PCPCGSGKKFKSCC 220
Cdd:PRK01752 139 PCVCGSGKKFKHCC 152
PRK12318 PRK12318
methionyl aminopeptidase;
202-219 1.65e-03

methionyl aminopeptidase;


Pssm-ID: 183434 [Multi-domain]  Cd Length: 291  Bit Score: 38.65  E-value: 1.65e-03
                         10
                 ....*....|....*...
gi 489956364 202 VGRNDPCPCGSGKKFKSC 219
Cdd:PRK12318   1 MKRNDPCWCGSGKKWKHC 18
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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