|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
1-806 |
0e+00 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 1503.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 1 MSGWPRIYYKLLNLPLSVLVKSKSIPAEPALELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEVDGTLLP 80
Cdd:PRK04974 1 MSGWRRLYYKLLNLPLKLLVKSKVIPADPAEELGLDPSRPIVYVLPYNSLSDLLTLRKQCLKLGLPDPLEPLEINGLQLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 81 RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPDLDVQMVPVSVMFGRRPGREKGeenpPLRMLNG--------IQK 152
Cdd:PRK04974 81 RYVFLHGGPRLFGYRTPKEESSPLFHRLLDLHRQNPELDVQLVPVSVFWGRAPGKEDS----ELRLLNGdnwavpgrLRK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 153 FFAVSWLGRDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVED 232
Cdd:PRK04974 157 LFAILWLGRDTFVRFSPPVSLRYMADEHGTDKRIARKLARVARVHFRRQRLAAIGPDLPHRQALFNKLLASPAIKKAIED 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 233 EARSKKISHEKAQQNAIALMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDY 312
Cdd:PRK04974 237 EAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 313 LLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG 392
Cdd:PRK04974 317 LLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGYSVEYFVEGGRSRTG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 393 RLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEP 472
Cdd:PRK04974 397 RLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLRNFGQGYVNFGEP 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 473 LPLMTYLNHHVPEWRESIDPIEAVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCY 552
Cdd:PRK04974 477 IPLNDYLNQHVPEWRESIDPIEEQRPAWLTPAVNNLANQVMVRINNAAAANPVNLCALALLASRQRALDREQLIEQLDLY 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 553 LDIMRNVPYSVDSTVPSATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRR 632
Cdd:PRK04974 557 LQLLRNVPYSSDTTVPEGSGEELIDHALSLNKFEVEKDTLGDIISLDREQAVLMTYYRNNILHLFVLPSLIASIVTHNRR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 633 ISRQELLRHIQAIYPMLKAELFLRWSKDELAAELDKMTAEMHRQGLITISDDELHINPSRSRTLQLLASGARETLQRYAI 712
Cdd:PRK04974 637 ISRDELLRIVNALYPFLKAELFLRWDEEELPEVIDQIIDELVRQGLITLDDDELHINPPRSRELQLLAAGVRETLQRYAI 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 713 TFWLLSANPSINRGTLEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYIS--DTGDAEPEETMKVYQMLAEL 790
Cdd:PRK04974 717 TLSLLSGSPNISRSELEKESHLLAQRLSVLHGINAPEFFDKALFSSFIQTLREEGYIRddDSGDLEFEETLEIYAILKRL 796
|
810
....*....|....*.
gi 489957015 791 ITADVRLTIESSTQGE 806
Cdd:PRK04974 797 LSPEVRLTIEQVAQAE 812
|
|
| plsB |
TIGR03703 |
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, ... |
11-799 |
0e+00 |
|
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, glycerol-3-phosphate O-acyltransferase, present in E. coli and numerous related species. In many bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274732 [Multi-domain] Cd Length: 799 Bit Score: 1281.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 11 LLNLPLSVLVKSKSIPAEPALELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEVDGTLLPRYVFIHGGPR 90
Cdd:TIGR03703 1 LLRLPLSLLVRSKVIPSDPIQELGLDPERPIVYVLPTRSLSDLLALQKACRKLGLPDPLEPLVIGGQRLPRYVFLDRPPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 91 VFTYYTPKEESIKLFHDYLDLHRSNPDLDVQMVPVSVMFGRRPGREKGEEN----PPLRMLNGIQKFFAVSWLGRDSFVR 166
Cdd:TIGR03703 81 LFSDRQKKSTSLPLLHRLLELHREDPELDVQLVPVSVFWGRAPGKESSGWKllflDSWASPGRLRKFLIVLFLGRDNFVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 167 FSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQ 246
Cdd:TIGR03703 161 FSPPVSLRYMADEHGTDESIAHKLARVARVHFRRQRLAAIGPDLSHRRTLFNKLLASPSVRKAIRDEAKSKKISEEKARK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 247 NAIALMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVP 326
Cdd:TIGR03703 241 RALKYLDEIAADYSYSLIRFLDRFLTWLWNKLYQGINVNNADRVRKLAQKGHEIIYVPCHRSHMDYLLLSYVLYHEGLVP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 327 PHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTI 406
Cdd:TIGR03703 321 PHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSAVFREYLHELFAKGYSVEYFVEGGRSRTGRLLPPKTGMLAMTL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 407 QAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPLPLMTYLNHHVPEW 486
Cdd:TIGR03703 401 QAMLRGIRRPITLVPVYIGYEHVMEVATYLKELRGKRKEKESVFGVLKTLRKLRNFGQGYVNFGEPINLNDYLNKHVPNW 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 487 RESIDPIEAVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIMRNVPYSVDST 566
Cdd:TIGR03703 481 RDDINPIEEEKPTWLTPAVNELANQVMTRINNAAAVNAVNLCALALLASRKHALSREELLAQLDLYLSLLRNVPYSERST 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 567 VPSATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRRISRQELLRHIQAIY 646
Cdd:TIGR03703 561 VPEEDPEELLEHALELNKFTVEEDSLGEIISLDREQAVLMTYYRNNILHLFALPSLVASIVIHNKKISRAELQALVRLLY 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 647 PMLKAELFLRWSKDELAAELDKMTAEMHRQGLITISDDELHINPSRSR---TLQLLASGARETLQRYAITFWLLSANPSI 723
Cdd:TIGR03703 641 PLLKAELFLRWSEEELPEVIDRILDELVRQGLIEQDGDVLTRNAARSRefvQLQLLAASIQETLQRYAITLSLLQRSGSI 720
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489957015 724 NRGTLEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDA--EPEETMK-VYQMLAELITADVRLTI 799
Cdd:TIGR03703 721 SRDALEKQSQQLAQRLSVLHGINAPEFFDKAVFSTFIATLREQGYLDDDGDGklIFDEKLEeLADQLKALLSPEVRQTI 799
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
11-804 |
0e+00 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 1021.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 11 LLNLPLSVLVKSKSIPAEPAlELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPleplevdgtllpryvfihggpr 90
Cdd:COG2937 2 LLRLPLKLLVKSKVIPEDTA-ELELDPSKPVVYVLPYRSLSDLLVLRRQCRKLGLPDP---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 91 vftyytpkeesiklfhdyldlhrsnpdldVQMVPVSVMFgrrpgrekgeenpplrmlngiqkffavswlgrdSFVRFSPS 170
Cdd:COG2937 59 -----------------------------IQLVPVSVLW---------------------------------TFVRFGEP 76
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 171 VSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQNAIA 250
Cdd:COG2937 77 VSLRELLDEGGSDERLARKLARVLRVHFRRQRRAVIGPDLKHRRDLIERLLRSPAVRKAIEEEAKSKGISEEKARKEARR 156
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 251 LMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAhDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIA 330
Cdd:COG2937 157 YLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVDNLERLRELA-KGHEIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIA 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 331 AGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAML 410
Cdd:COG2937 236 AGINLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFL 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 411 RGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLR-NLGQGYVNFGEPLPLMTYLNHHVPEWRES 489
Cdd:COG2937 316 RGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRrRFGRVYVNFGEPISLSEYLDQHVPDWRES 395
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 490 IDpieaVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIMRNVPYSVDSTVPS 569
Cdd:COG2937 396 ED----LRPEWLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALTEAELLAQLDLYLDLLRNVPYSLSVTLPE 471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 570 ATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRRISRQELLRHIQAIYPML 649
Cdd:COG2937 472 LTPEELLEHLLSLGLIEVEKDGLGDVISIDDEQAVLLTYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLL 551
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 650 KAELFLRWSkDELAAELDKMTAEMHRQGLITISDDELHINPSRSRTLQLLASGARETLQRYAITFWLLSANPS--INRGT 727
Cdd:COG2937 552 KAELFLRWD-AEFEEVLDEELDELVRQGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSgtLDRKE 630
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489957015 728 LEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPEETMKVYQMLAELITADVRLTIESSTQ 804
Cdd:COG2937 631 LEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDDEDGKDEKLEELADDARELLSPELRQTIQRIAR 707
|
|
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
279-480 |
5.72e-89 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 279.07 E-value: 5.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 279 YQGINVH--NAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTF 356
Cdd:cd07993 1 FDGVQVNegQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 357 KGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYA 436
Cdd:cd07993 81 GKDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEELYA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 489957015 437 KELRGATKEKESLPQMLRGLSKLR-NLGQGYVNFGEPLPLMTYLN 480
Cdd:cd07993 161 EELLGPPKPKESLSGLLGASKILReNFGRIRVDFGEPISLREYLG 205
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
282-425 |
8.04e-34 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 126.24 E-value: 8.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 282 INVHNAERVRQlahdGHEIVYVPCHRSHMDYLLLSYVLYHQGlVPPHIAAGINL-NFWPAGPIFRRLGAFFIRRtfkGNK 360
Cdd:pfam01553 2 IEVHGLENLPR----GGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489957015 361 LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYIG 425
Cdd:pfam01553 74 KDAAGTLEYLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
300-426 |
6.94e-26 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 102.82 E-value: 6.94e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 300 IVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKgnKLYSTVFREYLgELFSRGYS 379
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNG--RKARAALREAV-ELLKEGEW 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 489957015 380 VEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYIGY 426
Cdd:smart00563 78 LLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRG 117
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK04974 |
PRK04974 |
glycerol-3-phosphate 1-O-acyltransferase PlsB; |
1-806 |
0e+00 |
|
glycerol-3-phosphate 1-O-acyltransferase PlsB;
Pssm-ID: 235325 [Multi-domain] Cd Length: 818 Bit Score: 1503.59 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 1 MSGWPRIYYKLLNLPLSVLVKSKSIPAEPALELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEVDGTLLP 80
Cdd:PRK04974 1 MSGWRRLYYKLLNLPLKLLVKSKVIPADPAEELGLDPSRPIVYVLPYNSLSDLLTLRKQCLKLGLPDPLEPLEINGLQLP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 81 RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRSNPDLDVQMVPVSVMFGRRPGREKGeenpPLRMLNG--------IQK 152
Cdd:PRK04974 81 RYVFLHGGPRLFGYRTPKEESSPLFHRLLDLHRQNPELDVQLVPVSVFWGRAPGKEDS----ELRLLNGdnwavpgrLRK 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 153 FFAVSWLGRDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVED 232
Cdd:PRK04974 157 LFAILWLGRDTFVRFSPPVSLRYMADEHGTDKRIARKLARVARVHFRRQRLAAIGPDLPHRQALFNKLLASPAIKKAIED 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 233 EARSKKISHEKAQQNAIALMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDY 312
Cdd:PRK04974 237 EAKSKKISHEKARQNAIAYMDEIAADYSYSAIRLADRFLTWLWNRLYQGINVHNAERVRQLAQDGHEIVYVPCHRSHMDY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 313 LLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG 392
Cdd:PRK04974 317 LLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSTVFREYLGELFARGYSVEYFVEGGRSRTG 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 393 RLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEP 472
Cdd:PRK04974 397 RLLQPKTGMLAMTLQAMLRGSRRPITLVPVYIGYEHVMEVGTYAKELRGAPKEKESLFQVLRGIRKLRNFGQGYVNFGEP 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 473 LPLMTYLNHHVPEWRESIDPIEAVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCY 552
Cdd:PRK04974 477 IPLNDYLNQHVPEWRESIDPIEEQRPAWLTPAVNNLANQVMVRINNAAAANPVNLCALALLASRQRALDREQLIEQLDLY 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 553 LDIMRNVPYSVDSTVPSATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRR 632
Cdd:PRK04974 557 LQLLRNVPYSSDTTVPEGSGEELIDHALSLNKFEVEKDTLGDIISLDREQAVLMTYYRNNILHLFVLPSLIASIVTHNRR 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 633 ISRQELLRHIQAIYPMLKAELFLRWSKDELAAELDKMTAEMHRQGLITISDDELHINPSRSRTLQLLASGARETLQRYAI 712
Cdd:PRK04974 637 ISRDELLRIVNALYPFLKAELFLRWDEEELPEVIDQIIDELVRQGLITLDDDELHINPPRSRELQLLAAGVRETLQRYAI 716
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 713 TFWLLSANPSINRGTLEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYIS--DTGDAEPEETMKVYQMLAEL 790
Cdd:PRK04974 717 TLSLLSGSPNISRSELEKESHLLAQRLSVLHGINAPEFFDKALFSSFIQTLREEGYIRddDSGDLEFEETLEIYAILKRL 796
|
810
....*....|....*.
gi 489957015 791 ITADVRLTIESSTQGE 806
Cdd:PRK04974 797 LSPEVRLTIEQVAQAE 812
|
|
| plsB |
TIGR03703 |
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, ... |
11-799 |
0e+00 |
|
glycerol-3-phosphate O-acyltransferase; Members of this protein family are PlsB, glycerol-3-phosphate O-acyltransferase, present in E. coli and numerous related species. In many bacteria, PlsB is not found, and appears to be replaced by a two enzyme system for 1-acyl-glycerol-3-phosphate biosynthesis, the PlsX/Y system. [Fatty acid and phospholipid metabolism, Biosynthesis]
Pssm-ID: 274732 [Multi-domain] Cd Length: 799 Bit Score: 1281.42 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 11 LLNLPLSVLVKSKSIPAEPALELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEVDGTLLPRYVFIHGGPR 90
Cdd:TIGR03703 1 LLRLPLSLLVRSKVIPSDPIQELGLDPERPIVYVLPTRSLSDLLALQKACRKLGLPDPLEPLVIGGQRLPRYVFLDRPPP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 91 VFTYYTPKEESIKLFHDYLDLHRSNPDLDVQMVPVSVMFGRRPGREKGEEN----PPLRMLNGIQKFFAVSWLGRDSFVR 166
Cdd:TIGR03703 81 LFSDRQKKSTSLPLLHRLLELHREDPELDVQLVPVSVFWGRAPGKESSGWKllflDSWASPGRLRKFLIVLFLGRDNFVR 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 167 FSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQ 246
Cdd:TIGR03703 161 FSPPVSLRYMADEHGTDESIAHKLARVARVHFRRQRLAAIGPDLSHRRTLFNKLLASPSVRKAIRDEAKSKKISEEKARK 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 247 NAIALMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVP 326
Cdd:TIGR03703 241 RALKYLDEIAADYSYSLIRFLDRFLTWLWNKLYQGINVNNADRVRKLAQKGHEIIYVPCHRSHMDYLLLSYVLYHEGLVP 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 327 PHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTI 406
Cdd:TIGR03703 321 PHIAAGINLNFWPAGPIFRRGGAFFIRRSFKGNKLYSAVFREYLHELFAKGYSVEYFVEGGRSRTGRLLPPKTGMLAMTL 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 407 QAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLRNLGQGYVNFGEPLPLMTYLNHHVPEW 486
Cdd:TIGR03703 401 QAMLRGIRRPITLVPVYIGYEHVMEVATYLKELRGKRKEKESVFGVLKTLRKLRNFGQGYVNFGEPINLNDYLNKHVPNW 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 487 RESIDPIEAVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIMRNVPYSVDST 566
Cdd:TIGR03703 481 RDDINPIEEEKPTWLTPAVNELANQVMTRINNAAAVNAVNLCALALLASRKHALSREELLAQLDLYLSLLRNVPYSERST 560
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 567 VPSATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRRISRQELLRHIQAIY 646
Cdd:TIGR03703 561 VPEEDPEELLEHALELNKFTVEEDSLGEIISLDREQAVLMTYYRNNILHLFALPSLVASIVIHNKKISRAELQALVRLLY 640
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 647 PMLKAELFLRWSKDELAAELDKMTAEMHRQGLITISDDELHINPSRSR---TLQLLASGARETLQRYAITFWLLSANPSI 723
Cdd:TIGR03703 641 PLLKAELFLRWSEEELPEVIDRILDELVRQGLIEQDGDVLTRNAARSRefvQLQLLAASIQETLQRYAITLSLLQRSGSI 720
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489957015 724 NRGTLEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDA--EPEETMK-VYQMLAELITADVRLTI 799
Cdd:TIGR03703 721 SRDALEKQSQQLAQRLSVLHGINAPEFFDKAVFSTFIATLREQGYLDDDGDGklIFDEKLEeLADQLKALLSPEVRQTI 799
|
|
| PlsB |
COG2937 |
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate ... |
11-804 |
0e+00 |
|
Glycerol-3-phosphate O-acyltransferase [Lipid transport and metabolism]; Glycerol-3-phosphate O-acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 442180 [Multi-domain] Cd Length: 707 Bit Score: 1021.40 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 11 LLNLPLSVLVKSKSIPAEPAlELGLDTSRPIMYVLPYNSKADLLTLRAQCLAHDLPDPleplevdgtllpryvfihggpr 90
Cdd:COG2937 2 LLRLPLKLLVKSKVIPEDTA-ELELDPSKPVVYVLPYRSLSDLLVLRRQCRKLGLPDP---------------------- 58
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 91 vftyytpkeesiklfhdyldlhrsnpdldVQMVPVSVMFgrrpgrekgeenpplrmlngiqkffavswlgrdSFVRFSPS 170
Cdd:COG2937 59 -----------------------------IQLVPVSVLW---------------------------------TFVRFGEP 76
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 171 VSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQNAIA 250
Cdd:COG2937 77 VSLRELLDEGGSDERLARKLARVLRVHFRRQRRAVIGPDLKHRRDLIERLLRSPAVRKAIEEEAKSKGISEEKARKEARR 156
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 251 LMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNAERVRQLAhDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIA 330
Cdd:COG2937 157 YLREIAADFSYSAIRFLDRVLRWLWNRLYDGIRVDNLERLRELA-KGHEIVYVPCHRSHMDYLLLSYVLYHNGLVPPHIA 235
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 331 AGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAML 410
Cdd:COG2937 236 AGINLNFWPLGPILRRGGAFFIRRSFKGNKLYSAVFREYLAELFERGYSVEYFIEGGRSRTGRLLPPKTGMLSMTVQAFL 315
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 411 RGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKLR-NLGQGYVNFGEPLPLMTYLNHHVPEWRES 489
Cdd:COG2937 316 RGARRPVVFVPVYIGYERVLEVGSYAKELRGGEKKKESLGGLLRALRKLRrRFGRVYVNFGEPISLSEYLDQHVPDWRES 395
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 490 IDpieaVRPAWLTPTVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIMRNVPYSVDSTVPS 569
Cdd:COG2937 396 ED----LRPEWLRPAVDKLAFEIMVRINRAAAVNPVNLVALALLASPKRALTEAELLAQLDLYLDLLRNVPYSLSVTLPE 471
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 570 ATASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRRISRQELLRHIQAIYPML 649
Cdd:COG2937 472 LTPEELLEHLLSLGLIEVEKDGLGDVISIDDEQAVLLTYYRNNILHLFALPALIASALLANRRISRAELLELVRLLYPLL 551
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 650 KAELFLRWSkDELAAELDKMTAEMHRQGLITISDDELHINPSRSRTLQLLASGARETLQRYAITFWLLSANPS--INRGT 727
Cdd:COG2937 552 KAELFLRWD-AEFEEVLDEELDELVRQGLLEREGDTLRRPPARFRQLQLLAHVLRETLERYAIVLSLLAKLGSgtLDRKE 630
|
730 740 750 760 770 780 790
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489957015 728 LEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGDAEPEETMKVYQMLAELITADVRLTIESSTQ 804
Cdd:COG2937 631 LEKESLLLAQRLSLLHGINAPEFFDKALFRNFIQTLREQGYLDDDEDGKDEKLEELADDARELLSPELRQTIQRIAR 707
|
|
| LPLAT_DHAPAT-like |
cd07993 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; ... |
279-480 |
5.72e-89 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: GPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and similar proteins.
Pssm-ID: 153255 [Multi-domain] Cd Length: 205 Bit Score: 279.07 E-value: 5.72e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 279 YQGINVH--NAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTF 356
Cdd:cd07993 1 FDGVQVNegQLERLRKAAQEGHPVVLLPTHRSYLDFLLLSFILFSLGLPLPHIAAGENLNIPILGTLLRRLGAFFIRRSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 357 KGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYA 436
Cdd:cd07993 81 GKDPLYRAVLQEYVQELLKNGQPLEFFIEGTRSRTGKLLPPKLGLLSVVVEAYLKGSVPDVLIVPVSISYDRVLEEELYA 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 489957015 437 KELRGATKEKESLPQMLRGLSKLR-NLGQGYVNFGEPLPLMTYLN 480
Cdd:cd07993 161 EELLGPPKPKESLSGLLGASKILReNFGRIRVDFGEPISLREYLG 205
|
|
| PRK03355 |
PRK03355 |
glycerol-3-phosphate 1-O-acyltransferase; |
187-774 |
1.74e-55 |
|
glycerol-3-phosphate 1-O-acyltransferase;
Pssm-ID: 179567 [Multi-domain] Cd Length: 783 Bit Score: 204.56 E-value: 1.74e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 187 AQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRL 266
Cdd:PRK03355 155 ARFVRRRAALALERAERRILGPQYKVPRLVKPEILASARFRAGLAKIAAKLGRPPGATVREAGKMLDELVAGWSRVSVDL 234
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 267 SDRiLGFTWNRLYQGINVHNAERVRQLAHD--GHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIF 344
Cdd:PRK03355 235 VSV-LGRLFSRGFDPEIDYDEYELAALRALleEHPAVLLFSHRSYIDGLVVPVAMQENRLPPVHVFGGINLSFGPMGPIM 313
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 345 RRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYI 424
Cdd:PRK03355 314 RRSGMIFIRRNIGDDPLYKYVLREYVGYLVEKRFNLSWYIEGTRSRTGKLLPPKLGLLSYVADAYLDGRSDDVLLQPVSI 393
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 425 GYEHVMEVGTYAKELRGATKEKESLPQMLRGLSKL--RNLGQGYVNFGEPLPLMTYLNhhvPEWRESIDPIEAVRPAwlt 502
Cdd:PRK03355 394 SFDQLHEIGEYAAEARGGEKTPEGLRWLYNYIKAQgeRNYGKIYVRFGEPVSMRQYLG---APHGPLTQDPDAKRLA--- 467
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 503 ptVNGIASELMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIM--RNVPYS---VDSTVP---SATASE 574
Cdd:PRK03355 468 --LQKMAFEVAWRINQVTPVTATSLVSLLLLGTRGRALTLDELHHTLQDSLDYLerRQLPVStsaLRLRDPegvRAALDA 545
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 575 LIDhALQMNKFEVEKDTIGDIiilPREQAVLMTYYRNNITHMLMLPSLMAAIITQHRRISRQELLRHIQA----IYPMLK 650
Cdd:PRK03355 546 LSN-GGPVTRVDSGREPVWYI---APDDHLVAAFYRNSVIHAFLERAIVELALAAAAHVDEGDRLAAFWDqamrLRDLLK 621
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 651 AELFLRWS---KDELAAELDKMTAEMHRQglitISDDELHINPSRSRTLQLLASGA-RETLQRYAITFWLLSANP--SIN 724
Cdd:PRK03355 622 FEFFFADSdafRANLRAEMAWIDPDWEDR----LAAGGDEIDALLRAKRPLMAHAMlRPFFEAYEVVADVLRDAPpdTID 697
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 489957015 725 RGTLEKESRTLAQRLSVLHGINAPEFFDKAVFSSLVLTLRDEGYISDTGD 774
Cdd:PRK03355 698 EKELTALALGLGRQYVLQGRVRSSESVSTLLFATARQLARDQGLLEPAPD 747
|
|
| PTZ00374 |
PTZ00374 |
dihydroxyacetone phosphate acyltransferase; Provisional |
220-481 |
3.31e-39 |
|
dihydroxyacetone phosphate acyltransferase; Provisional
Pssm-ID: 240389 [Multi-domain] Cd Length: 1108 Bit Score: 156.96 E-value: 3.31e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 220 LLASKAIARAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLSDRILGFTWNRLYQGINVHNA--ERV-RQLAHD 296
Cdd:PTZ00374 548 ILAQPSIQRLMTALAKKEGASEKDVEARAKAILRTCGDNLNHVQCRLFGLMVRRILFRLYDRVSLNSGafERLhRYVAMP 627
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 297 GHEIVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINlnFWPAGPI---FRRLGAFFIRRTFKGNKLYSTVFREYLGEL 373
Cdd:PTZ00374 628 RVAVVLLPLHRSYIDFIIMTYLLAVMGLPLPHVCAGDD--FLRMGPIatlMRGSGAFFMRRSFRDDPLYAALFKEYVRHL 705
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 374 FSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTR--PITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQ 451
Cdd:PTZ00374 706 VLRRRPLEFFIEGTRSRTGKTMAPKLGLLKFICDTFYEGQQEldDVLIIPVSLSYDELLETTLYAKEQLGVSKPKENPGN 785
|
250 260 270
....*....|....*....|....*....|.
gi 489957015 452 MLRGLSKL-RNLGQGYVNFGEPLPLMTYLNH 481
Cdd:PTZ00374 786 LLRARSLLkRRHGKIHVHIGEPVSLRSFKDH 816
|
|
| Acyltransferase |
pfam01553 |
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis ... |
282-425 |
8.04e-34 |
|
Acyltransferase; This family contains acyltransferases involved in phospholipid biosynthesis and other proteins of unknown function. This family also includes tafazzin, the Barth syndrome gene.
Pssm-ID: 366704 [Multi-domain] Cd Length: 131 Bit Score: 126.24 E-value: 8.04e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 282 INVHNAERVRQlahdGHEIVYVPCHRSHMDYLLLSYVLYHQGlVPPHIAAGINL-NFWPAGPIFRRLGAFFIRRtfkGNK 360
Cdd:pfam01553 2 IEVHGLENLPR----GGPAIVVANHQSYLDVLLLSLALYKRG-RPLVFVAKKELfDIPLVGWLMRLLGCIFIDR---KNR 73
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489957015 361 LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYIG 425
Cdd:pfam01553 74 KDAAGTLEYLVELLREGKLVVIFPEGTRSREGELLPFKKGAFRLAIEA-------GVPIVPVAIS 131
|
|
| PRK11915 |
PRK11915 |
lysophospholipid acyltransferase; |
306-475 |
3.28e-26 |
|
lysophospholipid acyltransferase;
Pssm-ID: 237022 [Multi-domain] Cd Length: 621 Bit Score: 114.66 E-value: 3.28e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 306 HRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVE 385
Cdd:PRK11915 123 HRSYLDGMLLPEVILANRLSPALTFGGANLNFFPMGAWAKRTGAIFIRRQTKDIPVYRFVLRAYAAQLVQNHVNLTWSIE 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 386 GGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMLR-GLSKLRNLGQ 464
Cdd:PRK11915 203 GGRTRTGKLRPPVFGILRYITDAVDEIDGPEVYLVPTSIVYDQLHEVEAMTTEAYGAVKRPEDLRFLVRlARQQGERLGR 282
|
170
....*....|.
gi 489957015 465 GYVNFGEPLPL 475
Cdd:PRK11915 283 AYLDFGEPLPL 293
|
|
| PlsC |
smart00563 |
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either ... |
300-426 |
6.94e-26 |
|
Phosphate acyltransferases; Function in phospholipid biosynthesis and have either glycerolphosphate, 1-acylglycerolphosphate, or 2-acylglycerolphosphoethanolamine acyltransferase activities. Tafazzin, the product of the gene mutated in patients with Barth syndrome, is a member of this family.
Pssm-ID: 214724 [Multi-domain] Cd Length: 118 Bit Score: 102.82 E-value: 6.94e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 300 IVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKgnKLYSTVFREYLgELFSRGYS 379
Cdd:smart00563 1 ALVVANHQSFLDPLVLSALLPRKLGRVRFVAKKELFYVPLLGWLLRLLGAIFIDRSNG--RKARAALREAV-ELLKEGEW 77
|
90 100 110 120
....*....|....*....|....*....|....*....|....*..
gi 489957015 380 VEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYIGY 426
Cdd:smart00563 78 LLIFPEGTRSRPGKLLPFKKGAARLALEA-------GVPIVPVAIRG 117
|
|
| GPAT_C |
pfam19277 |
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal ... |
435-685 |
3.01e-16 |
|
Glycerol-3-phosphate acyltransferase C-terminal region; This entry represents the C-terminal region of Glycerol-3-phosphate acyltransferase.
Pssm-ID: 466024 Cd Length: 370 Bit Score: 81.41 E-value: 3.01e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 435 YAKELRGATKEKESLPQMLRGLSKL--RNLGQGYVNFGEPLPLMTYLNhhvPEWRESIDPIEAVRPAwltptVNGIASEL 512
Cdd:pfam19277 1 YAAELLGGPKKPEGLSWLLSYARSQlsLKLGRVYVRFGEPWSLREFLD---EQGDRPATDAARRRLA-----LQKLAFEV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 513 MVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQIDCYLDIM--RNVPYSVDSTVPSataSELIDHALQmnkFEVEKD 590
Cdd:pfam19277 73 LSRINRVTPVMPTALVGTVLLTLRGRALTLSELIRRVEWLLDYIraRGGPVAHFGDLRT---EEVVDRALD---VLGNAG 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 591 TIGDI--------IILPREQAVLmTYYRNNITHMLMLPSL----MAAIITQHRR-ISRQELLRHIQAIYPMLKAELFLRw 657
Cdd:pfam19277 147 LVTRVdggpepvyYIAPEDHFQA-SFYRNMTIHLFVERAIvelaLLTKVKAAQRgDSYEALWDQVLRLRDLLKFEFFFP- 224
|
250 260 270
....*....|....*....|....*....|...
gi 489957015 658 SKDELAAELDkmtAEMH-----RQGLITISDDE 685
Cdd:pfam19277 225 PKEGFRENLR---AELDlldpwEDRVITGERDI 254
|
|
| PlsC |
COG0204 |
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; ... |
255-490 |
1.40e-13 |
|
1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid transport and metabolism]; 1-acyl-sn-glycerol-3-phosphate acyltransferase is part of the Pathway/BioSystem: Phospholipid biosynthesis
Pssm-ID: 439974 [Multi-domain] Cd Length: 215 Bit Score: 70.42 E-value: 1.40e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 255 IAANFSYEMIRlsdRILGFTWNRLYQGINVHNAERvrqLAHDGHeIVYVPCHRSHMDYLLLSYVLYHqglvPPHIAAGIN 334
Cdd:COG0204 7 LLRRFRYRLVR---LWARLLLRLLGVRVRVEGLEN---LPADGP-VLIVANHQSWLDILLLLAALPR----PVRFVAKKE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 335 LNFWP-AGPIFRRLGAFFIRRTFKGNKLYSTvfrEYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrgg 413
Cdd:COG0204 76 LFKIPlLGWLLRALGAIPVDRSKRRAALRAL---RQAVEALKAGESLVIFPEGTRSPDGRLLPFKTGAARLALEA----- 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 489957015 414 trPITLVPIYIgyehvmeVGTYAKELRGatkekeslpqmlrglsKLRNLGQGYVNFGEPLPLMTYLNHHVPEWRESI 490
Cdd:COG0204 148 --GVPIVPVAI-------DGTERALPKG----------------FLPRPGKVTVRIGPPIDPSDLEGEDRRELAERL 199
|
|
| LPLAT_AGPAT-like |
cd07989 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; ... |
269-433 |
8.01e-12 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.
Pssm-ID: 153251 [Multi-domain] Cd Length: 184 Bit Score: 64.60 E-value: 8.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 269 RILGFTWNRlyqgINVHNAERvrqLAHDGHeIVYVPCHRSHMDYLLLSYVLYHqglvPPHIAAGINLNFWP-AGPIFRRL 347
Cdd:cd07989 3 LLLRLLGVR----VRVEGLEN---LPPKGP-VIIVANHQSYLDPLVLGAALPR----PIRFVAKKELFKIPfLGWLLRLL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 348 GAFFIRRtfKGNKLYSTVFREyLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYI-GY 426
Cdd:cd07989 71 GAIPIDR--GNGRSAREALRE-AIEALKEGESVVIFPEGTRSRDGELLPFKSGAFRLAKEA-------GVPIVPVAIsGT 140
|
....*..
gi 489957015 427 EHVMEVG 433
Cdd:cd07989 141 WGSLPKG 147
|
|
| LPLAT |
cd06551 |
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ... |
279-427 |
9.08e-09 |
|
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).
Pssm-ID: 153244 [Multi-domain] Cd Length: 187 Bit Score: 55.88 E-value: 9.08e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 279 YQGINVHNAERVRQLAH----DGHEIVYVPCHRSHMDYLLLSYVLYhQGLVPPHIAAGINLNFwPAGPIFRRLGAFFIRR 354
Cdd:cd06551 3 YLLLNFFGFVRLEVKGPppppGGGPVLFVSNHSSWWDGLILFLLLE-RGLRRDVYGLMDEELL-ERYPFFTRLGAFSVDR 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489957015 355 TfkgNKLYSTVFREYLGELFSRGYS-VEYFVEGGRSR-TGRLLDPKTGTLSMTIQAmlrggtrPITLVPIYIGYE 427
Cdd:cd06551 81 D---SPRSAAKSLKYVARLLSKPGSvVWIFPEGTRTRrDKRPLQFKPGVAHLAEKA-------GVPIVPVALRYT 145
|
|
| LPLAT_ABO13168-like |
cd07988 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
300-428 |
7.56e-04 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ABO13168; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized phospholipid/glycerol acyltransferases such as the Acinetobacter baumannii ATCC 17978 locus ABO13168 putative acyltransferase, and similar proteins.
Pssm-ID: 153250 [Multi-domain] Cd Length: 163 Bit Score: 41.05 E-value: 7.56e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 300 IVYVPcHRSHMDYLLLSYVLYHQGlVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNklysTVfrEYLGELFSRGys 379
Cdd:cd07988 24 VIGAP-HTSNWDFVLGLLAAFALG-LKISFLGKHSLFKPPLGPFMRWLGGIPVDRSRAGG----LV--EQVVEEFRRR-- 93
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....
gi 489957015 380 vEYFV-----EGGRSRTGRLldpKTGTLSMTIQAMLrggtrPITLVpiYIGYEH 428
Cdd:cd07988 94 -EEFVlaiapEGTRSKVDKW---KTGFYHIARGAGV-----PILLV--YLDYKR 136
|
|
| LPLAT_AAK14816-like |
cd07992 |
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown ... |
269-428 |
1.87e-03 |
|
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: Unknown AAK14816-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are uncharacterized glycerol-3-phosphate acyltransferases such as the Plasmodium falciparum locus AAK14816 putative acyltransferase, and similar proteins.
Pssm-ID: 153254 [Multi-domain] Cd Length: 203 Bit Score: 40.32 E-value: 1.87e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 269 RILGFTWNRLYQG-INVHNAERVRqlaHDGHEIVYVPCHRSHMDYLLLSYVlyhqglVPPH---IAAGINLNFWPAGPIF 344
Cdd:cd07992 2 RLLSRVILRIYFRrITVVGRENVP---KDGPVIFLGNHPNALIDPLLLAAT------LRRPvrfLAKADLFKNPLIGWLL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957015 345 RRLGAFFIRR------TFKGNKLYSTVFREyLGELFSRGYSVEYFVEGGrSRTG-RLLDPKTGTLSMTIQAmLRGGTRPI 417
Cdd:cd07992 73 ESFGAIPVYRpkdlarGGIGKISNAAVFDA-VGEALKAGGAIGIFPEGG-SHDRpRLLPLKAGAARMALEA-LEAGQKDV 149
|
170
....*....|.
gi 489957015 418 TLVPIYIGYEH 428
Cdd:cd07992 150 KIVPVGLNYED 160
|
|
| |
