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Conserved domains on  [gi|489957480|ref|WP_003860787|]
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MULTISPECIES: Sec-independent protein translocase subunit TatA [Enterobacteriaceae]

Protein Classification

Sec-independent protein translocase subunit TatA( domain architecture ID 10011955)

Sec-independent protein translocase subunit TatA may form the protein-conducting channel of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-84 9.17e-41

Sec-independent protein translocase subunit TatA;


:

Pssm-ID: 179592  Cd Length: 89  Bit Score: 128.64  E-value: 9.17e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDE-----AKKEE 75
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADtnqeqAKTED 80


                ....*....
gi 489957480 76 AKRHDKEQV 84
Cdd:PRK03554 81 AKRHDKEQV 89
 
Name Accession Description Interval E-value
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-84 9.17e-41

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 128.64  E-value: 9.17e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDE-----AKKEE 75
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADtnqeqAKTED 80


                ....*....
gi 489957480 76 AKRHDKEQV 84
Cdd:PRK03554 81 AKRHDKEQV 89
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-72 1.84e-16

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 66.88  E-value: 1.84e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDEAK 72
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEELKKA 72
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 5.17e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 64.94  E-value: 5.17e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 489957480   3 GISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEN 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-56 2.14e-11

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 53.46  E-value: 2.14e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489957480   4 ISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQD 56
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
 
Name Accession Description Interval E-value
tatA PRK03554
Sec-independent protein translocase subunit TatA;
1-84 9.17e-41

Sec-independent protein translocase subunit TatA;


Pssm-ID: 179592  Cd Length: 89  Bit Score: 128.64  E-value: 9.17e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDE-----AKKEE 75
Cdd:PRK03554  1 MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADtnqeqAKTED 80


                ....*....
gi 489957480 76 AKRHDKEQV 84
Cdd:PRK03554 81 AKRHDKEQV 89
tatA PRK04598
twin-arginine translocase subunit TatA;
1-83 8.40e-29

twin-arginine translocase subunit TatA;


Pssm-ID: 179867  Cd Length: 81  Bit Score: 98.39  E-value: 8.40e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQeKTSQDADFTAKSIADKQDEAKKEeaKRHD 80
Cdd:PRK04598  1 MGGISIWQLLIIAVIVVLLFGTKKLRGIGSDLGSAVKGFKKAMSEEESAK-ANKKDADFEPKNLEQAKTEAAAE--KKKD 77


                ...
gi 489957480 81 KEQ 83
Cdd:PRK04598 78 KEQ 80
tatA PRK01833
Sec-independent protein translocase subunit TatA;
1-83 6.54e-21

Sec-independent protein translocase subunit TatA;


Pssm-ID: 167284  Cd Length: 74  Bit Score: 78.00  E-value: 6.54e-21
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEnkqektSQDADFtaKSIADKQDEAKKEEAKrhD 80
Cdd:PRK01833  1 MGGISIWQLLIIVAIIVLLFGTKKLRTLGTDLGESVKGFKKAMADDK------PKDAEF--EKVEAKEAASTEQKAK--E 70


                ...
gi 489957480 81 KEQ 83
Cdd:PRK01833 71 KEQ 73
tatA PRK02958
Sec-independent protein translocase subunit TatA;
1-73 2.53e-20

Sec-independent protein translocase subunit TatA;


Pssm-ID: 235091  Cd Length: 73  Bit Score: 76.54  E-value: 2.53e-20
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDEAKK 73
Cdd:PRK02958  1 MGSFSIWHWLIVLVIVVLVFGTKKLRNIGSDLGGAVKGFKDGMKEGETPQEAQAQQLPDSGTIDVEAKEKSKS 73
tatE PRK03625
twin-arginine translocase subunit TatE;
1-68 8.75e-18

twin-arginine translocase subunit TatE;


Pssm-ID: 179612  Cd Length: 67  Bit Score: 69.80  E-value: 8.75e-18
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSqDADFTAKSIADKQ 68
Cdd:PRK03625  1 MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMNDDDAAAKKGA-DVDLQAEKLSHKE 67
TatA COG1826
Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, ...
 1-72 1.84e-16

Twin-arginine protein secretion pathway components TatA and TatB [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 441431 [Multi-domain]  Cd Length: 72  Bit Score: 66.88  E-value: 1.84e-16
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDEAK 72
Cdd:COG1826   1 MFGIGFWELLIILVVALLVFGPKKLPELARSLGKAIREFKKAANEVKEELDEELKEEELRKSEKEAEELKKA 72
tatA PRK00442
twin-arginine translocase TatA/TatE family subunit;
3-57 2.31e-16

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234764  Cd Length: 92  Bit Score: 67.21  E-value: 2.31e-16
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 489957480  3 GISIWQ-LVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDA 57
Cdd:PRK00442  2 GIFDWKhWIVILVVVVLVFGTKKLKNLGSDVGESIKGFRKAMNEDEKEDKPAEQPA 57
tatE PRK01614
Sec-independent protein translocase subunit TatA;
1-83 2.47e-16

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234965  Cd Length: 85  Bit Score: 66.84  E-value: 2.47e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAKSIADKQDEAKKEEAKRHD 80
Cdd:PRK01614  1 MEGLSITKLLVVGILIVLLFGTSKLRTLGADLGAALKGFKKAMRNDDEVSTSVLGETKMSAETKTVAETKAASDSQAAAS 80


                ...
gi 489957480 81 KEQ 83
Cdd:PRK01614 81 VER 83
tatAE TIGR01411
twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E ...
 3-48 5.17e-16

twin arginine-targeting protein translocase, TatA/E family; This model distinguishes TatA/E from the related TatB, but does not distinguish TatA from TatE. The Tat (twin-arginine translocation) system is a Sec-independent exporter for folded proteins, often with a redox cofactor already bound, across the bacterial inner membrane. Functionally equivalent systems are found in the chloroplast and some in archaeal species. The signal peptide recognized by the Tat system is modeled by TIGR01409. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 273605 [Multi-domain]  Cd Length: 47  Bit Score: 64.94  E-value: 5.17e-16
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 489957480   3 GISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEN 48
Cdd:TIGR01411  1 GLSPPEWLIILVVILLLFGAKKLPELGRDLGKAIKEFKKALKEEED 46
tatA PRK00720
twin-arginine translocase TatA/TatE family subunit;
1-81 2.45e-12

twin-arginine translocase TatA/TatE family subunit;


Pssm-ID: 234822  Cd Length: 78  Bit Score: 56.59  E-value: 2.45e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDenkqEKTSQDADFTAKSIADKQDEAKKEEAKRHD 80
Cdd:PRK00720  1 MGSFSIWHWLIVLAVVLLLFGRGKISELMGDVAKGIKSFKKGMADD----DAPPAEPPEPVRTIDHKADEPVAPVKKDVG 76


                .
gi 489957480 81 K 81
Cdd:PRK00720 77 S 77
tatA PRK00575
Sec-independent protein translocase subunit TatA;
1-71 3.31e-12

Sec-independent protein translocase subunit TatA;


Pssm-ID: 234797 [Multi-domain]  Cd Length: 92  Bit Score: 56.29  E-value: 3.31e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFK---KAM-SDDENKQEKTSQDADFTAKSIADKQDEA 71
Cdd:PRK00575  1 MGSLSPWHWAILAVVVILLFGAKKLPDAARSLGKSLRIFKsevKEMqSDNKAEASAAAAQAPYQVATPTPVQSQR 75
tatA PRK04561
twin arginine translocase protein A; Provisional
 1-78 4.87e-12

twin arginine translocase protein A; Provisional


Pssm-ID: 179864  Cd Length: 75  Bit Score: 55.69  E-value: 4.87e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEnkqEKTSQDADFTAKSIADKQDEAKKEEAKR 78
Cdd:PRK04561  1 MGSFSIWHWLVVLVIVLLVFGTKRLTSGAKDLGSAVKEFKKGMHDDD---KPAGQLGDDSRSAEQAREAQAERDRDAR 75
TatA_B_E pfam02416
mttA/Hcf106 family; Members of this protein family are involved in a sec independent ...
 4-56 2.14e-11

mttA/Hcf106 family; Members of this protein family are involved in a sec independent translocation mechanism. This pathway has been called the DeltapH pathway in chloroplasts. Members of this family in E.coli are involved in export of redox proteins with a "twin arginine" leader motif.


Pssm-ID: 426762  Cd Length: 53  Bit Score: 53.46  E-value: 2.14e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|...
gi 489957480   4 ISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQD 56
Cdd:pfam02416  1 LGIPELLIILVVALLLFGPKKLPELGRALGKTLREFKKATKELEEEDEKEAQE 53
tatA PRK14859
twin arginine translocase protein A; Provisional
 1-58 1.49e-10

twin arginine translocase protein A; Provisional


Pssm-ID: 184861  Cd Length: 63  Bit Score: 51.65  E-value: 1.49e-10
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDAD 58
Cdd:PRK14859  1 MFGIGMPELIVILVIVLIVFGAGKLPEIGGGLGKSIKNFKKATSEKEEIEIKPTKKED 58
tatA PRK14857
TatA/E family twin arginine-targeting protein translocase;
3-77 7.99e-09

TatA/E family twin arginine-targeting protein translocase;


Pssm-ID: 184859  Cd Length: 90  Bit Score: 47.79  E-value: 7.99e-09
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 489957480  3 GISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFT---AKSIADKQDEAKKEEAK 77
Cdd:PRK14857  5 GIGLPEMAVILVIALLVFGPKKLPEIGRSLGKTLKGFQEASKEFENEIKREMAEPEQEvkaPAELESNQTNEANQEQV 82
tatA PRK14861
twin arginine translocase protein A; Provisional
 1-55 1.72e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 237837  Cd Length: 61  Bit Score: 46.12  E-value: 1.72e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKA----MSDDENKQEKTSQ 55
Cdd:PRK14861  2 FSNIGFPGLILILVVALIIFGPKKLPELGKALGKTLREFKKAtkelTDDDFQEKKKKEK 60
tatA PRK00191
twin arginine translocase protein A; Provisional
 7-55 6.16e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 234683 [Multi-domain]  Cd Length: 84  Bit Score: 45.33  E-value: 6.16e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 489957480  7 WQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFK---KAMSDDENKQEKTSQ 55
Cdd:PRK00191  6 WEIGIIVLLIIVLFGAKKLPDAARSIGRSMRIFKsevKEMSKDDQTPEQQQQ 57
tatA PRK01470
twin arginine translocase protein A; Provisional
 3-52 7.70e-08

twin arginine translocase protein A; Provisional


Pssm-ID: 179298  Cd Length: 51  Bit Score: 44.46  E-value: 7.70e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 489957480  3 GISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEK 52
Cdd:PRK01470  2 GMSFSHLLIVLLIIFVLFGAGKLPQVMSDLAKGLKAFKDGMKDDGSDNDK 51
tatA PRK14860
twin arginine translocase protein A; Provisional
 1-80 1.49e-07

twin arginine translocase protein A; Provisional


Pssm-ID: 184862  Cd Length: 64  Bit Score: 43.95  E-value: 1.49e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 489957480  1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEnkqektsqdadftaksIADKQDEAKKEEAKRHD 80
Cdd:PRK14860  1 MFGFGMPELIVILVIALVVFGPAKLPQLGQALGGAIRNFKKASNEED----------------VVTINNEKGKEDQARSD 64
tatA PRK14858
twin arginine translocase protein A; Provisional
 1-77 1.80e-06

twin arginine translocase protein A; Provisional


Pssm-ID: 184860  Cd Length: 108  Bit Score: 42.16  E-value: 1.80e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 489957480   1 MGGISIWQLVIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDENKQEKTSQDADFTAK--SIADKQDEAKKEEAK 77
Cdd:PRK14858   1 MFGIGMPELIVILVIALIVIGPQKLPDLARSLGRGLAEFKKATDDFKQSMQEESRTAEEKEKaeKLAETKKEAEAPEAK 79
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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