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Conserved domains on  [gi|490204666|ref|WP_004103105|]
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MULTISPECIES: oligopeptide ABC transporter permease OppC [Klebsiella]

Protein Classification

oligopeptide ABC transporter permease OppC( domain architecture ID 11487776)

oligopeptide ABC transporter permease OppC is the transmembrane subunit (TM) of the periplasmic binding protein (PBP)-dependent ABC transporter complex OppABCDF involved in the import of peptides and is responsible for mediating passage of peptides across the cytoplasmic membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 1-302 0e+00

oligopeptide ABC transporter permease OppC; Provisional


:

Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 520.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666   1 MMLSKKNNEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMES 80
Cdd:PRK15406   1 MMLSKKNSEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160
Cdd:PRK15406  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFL 240
Cdd:PRK15406 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490204666 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
Cdd:PRK15406 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
 
Name Accession Description Interval E-value
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 1-302 0e+00

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 520.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666   1 MMLSKKNNEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMES 80
Cdd:PRK15406   1 MMLSKKNSEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160
Cdd:PRK15406  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFL 240
Cdd:PRK15406 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490204666 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
Cdd:PRK15406 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 22-298 2.32e-103

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 303.19  E-value: 2.32e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  22 GRSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGG 101
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAA--HWLGTDQLGRDVLSRLLYGA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 102 RISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMAR 181
Cdd:COG1173   79 RISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 182 IVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDG 261
Cdd:COG1173  159 LVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEG 238

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 490204666 262 ANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALD 298
Cdd:COG1173  239 RNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 24-76 9.03e-14

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 64.74  E-value: 9.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490204666   24 SLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAP 76
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQDLSADLLPP 53
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 117-283 6.59e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 60.37  E-value: 6.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 117 ILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQN--------ILLIFVAIGMVSWLDMARIVRGQTL 188
Cdd:cd06261   17 VLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLlgwgilpgLGLPALILALLLIAPFARLIRRAAL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 189 SLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLsSWGALLSDGANSMEVS 268
Cdd:cd06261   97 ESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP-GTGLLLIFAILFPGDL 175

                        170
                 ....*....|....*
gi 490204666 269 PWLLLFPAGFLVVTL 283
Cdd:cd06261  176 GVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 1-302 0e+00

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 520.55  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666   1 MMLSKKNNEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMES 80
Cdd:PRK15406   1 MMLSKKNSEALENFSEKLEVEGRSLWQDARRRFMHNRAAVASLIVLVLIALFVILAPMLSQFAYDDTDWGMMSSAPDMES 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160
Cdd:PRK15406  81 GHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFL 240
Cdd:PRK15406 161 GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490204666 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
Cdd:PRK15406 241 SFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPKDR 302
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 22-298 2.32e-103

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 303.19  E-value: 2.32e-103
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  22 GRSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGG 101
Cdd:COG1173    1 PRSRWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQDLAARLQPPSAA--HWLGTDQLGRDVLSRLLYGA 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 102 RISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMAR 181
Cdd:COG1173   79 RISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWPGYAR 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 182 IVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDG 261
Cdd:COG1173  159 LVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTMLSEG 238

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 490204666 262 ANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALD 298
Cdd:COG1173  239 RNYLLTAPWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 23-300 4.25e-56

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 183.39  E-value: 4.25e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  23 RSLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQF---SYYDTDwgMMSSAPDMEsgHYFGTDSSGRDLLVRVAI 99
Cdd:PRK15082  22 RTPWHEFWRRFRRQHVALVAGLFVLLLIVVAIFAPWIAPYdaeNYFDYD--ALNAGPSLQ--HWFGVDSLGRDIFSRILV 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 100 GGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDM 179
Cdd:PRK15082  98 GARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAF 177

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 180 ARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLS 259
Cdd:PRK15082 178 ARLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLN 257

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 490204666 260 DGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
Cdd:PRK15082 258 EARADMVIAPHVALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
25-300 1.47e-47

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 161.14  E-value: 1.47e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  25 LWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSS---APDMEsgHYFGTDSSGRDLLVRVAIGG 101
Cdd:PRK09881  16 TRFNGAKLVWMLKGSPLTVTGAVIIVLMLLMMIFSPWLATHDPNAIDLTArllPPSAA--HWFGTDEVGRDLFSRVLVGS 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 102 RISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMAR 181
Cdd:PRK09881  94 QQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAMLAIAIVRIPFYVR 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 182 IVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDG 261
Cdd:PRK09881 174 LARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANG 253

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 490204666 262 ANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
Cdd:PRK09881 254 RNYVLDQWWYCAFPGAAILLTAVGFNLFGDGIRDLLDPK 292
nikC PRK10417
nickel transporter permease NikC; Provisional
 37-299 1.82e-46

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 157.52  E-value: 1.82e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  37 RAAVASLIVLVIIALFvtiAPMVTQFSYYDTDWGMMSSAPDMEsgHYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAV 116
Cdd:PRK10417   7 RLALIIIALLALIALT---SQWWLPYDPQAIDLPSRLLSPDAQ--HWLGTDHLGRDIFSRLMAGTRVSLGSVMACLLLVL 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 117 ILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFI 196
Cdd:PRK10417  82 ALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISLRQREFV 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 197 EAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA 276
Cdd:PRK10417 162 LAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIWTQPLLMFWPG 241

                        250       260
                 ....*....|....*....|...
gi 490204666 277 GFLVVTLFCFNFIGDGLRDALDP 299
Cdd:PRK10417 242 LALFISVMAFNLLGDALRDHLDP 264
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 62-300 4.14e-42

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 147.99  E-value: 4.14e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  62 FSYYDTDWGMMSSAPDMESG-HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRL 140
Cdd:COG4239  100 YSYDTINYDLPSPAPSPPSAeNWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRVDLLFQRF 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 141 LEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLG 220
Cdd:COG4239  180 IEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRHILPNAMV 259

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 221 VVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
Cdd:COG4239  260 ATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQ-APWLGLSAFVVLALMLSLLVFIGEAVRDAFDPR 338
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
33-300 5.52e-39

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 138.76  E-value: 5.52e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  33 FMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMESG----HYFGTDSSGRDLLVRVAIGGRISLMVG 108
Cdd:PRK10913  26 FKRNKGAVVGLVYVVIMLFIAIFANWIAPHNPAEQFRDALLAPPVWQEGgswaHILGTDDVGRDVLSRLMYGARLSLLVG 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 109 VAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTL 188
Cdd:PRK10913 106 CLVVVLSLVMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVL 185

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 189 SLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVS 268
Cdd:PRK10913 186 VEVNRDYVTASRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSA 265

                        250       260       270
                 ....*....|....*....|....*....|..
gi 490204666 269 PWLLLFPAGFLVVTLFCFNFIGDGLRDALDPK 300
Cdd:PRK10913 266 WWVVTFPGLAILLTVLAFNLMGDGLRDALDPK 297
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 74-299 8.45e-34

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 126.25  E-value: 8.45e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  74 SAPDMESghYFGTDSSGRDLLVRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFV 153
Cdd:PRK15021 115 SPPSRQN--WLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLI 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 154 ILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSM 233
Cdd:PRK15021 193 ILLSSVVQPNFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSS 272

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490204666 234 ILFESFLSFLGLGTQEPLSSWGALLSDGANSMEvSPWLLLfpAGFLVVT--LFCFNFIGDGLRDALDP 299
Cdd:PRK15021 273 ITTLTSLDFLGFGLPLGSPSLGELLLQGKNNLQ-APWLGI--TAFLSVAilLSLLIFIGEAVRDAFDP 337
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
31-298 3.68e-28

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 109.91  E-value: 3.68e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  31 RRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAPDMESG----HYFGTDSSGRDLLVRVAIGGRISLM 106
Cdd:COG4171   21 QSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSPDQQFIGALLLPPSWDDNgdvsFFLGTDDLGRDILSRLLYGARYTFG 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 107 VGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQ 186
Cdd:COG4171  101 SALLVVLAAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQFIHAIYQA 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 187 TLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSME 266
Cdd:COG4171  181 VHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLGDSLELIY 260

                        250       260       270
                 ....*....|....*....|....*....|..
gi 490204666 267 VSPWLLLFPAGFLVVTLFCFNFIGDGLRDALD 298
Cdd:COG4171  261 LAPWTVILPGLAIMFSVLIVNLVGDGLRRALN 292
PRK15111 PRK15111
peptide ABC transporter permease SapC;
24-298 2.32e-18

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 83.21  E-value: 2.32e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  24 SLWQDARRRFMHNRAAVASL---IVLVIIALF-VTIAP--MVTQFSYYD---TDWGMMSsapdmESGHYFGTDSSGRDLL 94
Cdd:PRK15111  14 GTLRTAWRKFYSDALAMVGLygcAGLALLCLFgGWLAPygIDQQFLGYQllpPSWSRYG-----EVSFFLGTDDLGRDVL 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  95 VRVAIGGRISLMVGVAAALVAVILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMV 174
Cdd:PRK15111  89 SRLLSGAAPTVGGAFVVTLAATLCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMFAVWLA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 175 SWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSW 254
Cdd:PRK15111 169 LLPRMVRSIYSAVHDELEKEYVIAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEW 248

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 490204666 255 GALLSDGANSMEVSPWLLLFPAGFLVVTLFCFNFIGDGLRDALD 298
Cdd:PRK15111 249 GAMLGDSLELIYVAPWTVMLPGAAIMLSVLLVNLLGDGIRRAII 292
OppC_N pfam12911
N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have ...
 24-76 9.03e-14

N-terminal TM domain of oligopeptide transport permease C; Oligopeptide permeases (Opp) have been identified in numerous gram-negative and -positive bacteria. These transport systems belong to the superfamily of highly conserved ATP-binding cassette transporters. Typically, Opp importers comprise a complex of five proteins. The oligopeptide-binding protein OppA is responsible for the capture of peptides from the external medium. Two integral highly hydrophobic membrane spanning proteins, OppB and OppC, form a channel through the membrane used for peptide translocation. This N-terminal domain appears to be the first TM domain of the molecule.


Pssm-ID: 463747 [Multi-domain]  Cd Length: 53  Bit Score: 64.74  E-value: 9.03e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490204666   24 SLWQDARRRFMHNRAAVASLIVLVIIALFVTIAPMVTQFSYYDTDWGMMSSAP 76
Cdd:pfam12911   1 SPWQDAWRRFRRNKLAMVGLVILLLLVLLAIFAPLLAPYDPDQQDLSADLLPP 53
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 117-283 6.59e-11

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 60.37  E-value: 6.59e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 117 ILGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQN--------ILLIFVAIGMVSWLDMARIVRGQTL 188
Cdd:cd06261   17 VLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLlgwgilpgLGLPALILALLLIAPFARLIRRAAL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 189 SLKRKEFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLsSWGALLSDGANSMEVS 268
Cdd:cd06261   97 ESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGP-GTGLLLIFAILFPGDL 175

                        170
                 ....*....|....*
gi 490204666 269 PWLLLFPAGFLVVTL 283
Cdd:cd06261  176 GVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 119-300 1.96e-10

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 58.85  E-value: 1.96e-10
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  119 GTLYGSLSG-YLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNIL----LIFVAIGMVSWLDMARIVRGQTLSLKRK 193
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILghgiLPAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666  194 EFIEAAQVGGVSTRNIVIRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEplsswGALLSDGANSMEVSpwLLL 273
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGL-----GLLLIEAILGYDYP--EIQ 153

                         170       180
                  ....*....|....*....|....*..
gi 490204666  274 FPAGFLVVTLFCFNFIGDGLRDALDPK 300
Cdd:pfam00528 154 GPVLAAALILLLLNLLVDILQRLLDPR 180
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 117-214 1.72e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 39.28  E-value: 1.72e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490204666 117 ILGTLYGSLSGYL-GGKVDSVMMRLLEILNSFPFMFFVILLVTFFG----------------------QNILLIFVAIGM 173
Cdd:COG0601  111 LIGIPLGILAALRrGSWLDRLITVLALLGISIPSFWLGLLLILLFAvklgwlpvsgrvspwedfldalRHLILPALTLAL 190

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 490204666 174 VSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTRNIVIRHI 214
Cdd:COG0601  191 GSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHA 231
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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