|
Name |
Accession |
Description |
Interval |
E-value |
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
5-393 |
0e+00 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 545.43 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTA 84
Cdd:COG0183 2 REVVIVDAVRTPFGRFGGALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNPARQAALLAGLPESVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMgHGELEDGLIS-ILTWPEGPYHNGITA 163
Cdd:COG0183 82 VTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMSRAPMLLPKARWGYRM-NAKLVDPMINpGLTDPYTGLSMGETA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 164 ENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKaTRLFATDEHPR-DTPREKLAALRPAFKADGV 242
Cdd:COG0183 161 ENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVPDRKG-EVVVDRDEGPRpDTTLEKLAKLKPAFKKDGT 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 243 VTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFA 322
Cdd:COG0183 240 VTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDIDLIEINEAFA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490207011 323 AQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:COG0183 320 AQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGGRYGLATMCIGGGQGIALIIER 390
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
8-393 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 537.45 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 8 VVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSV 87
Cdd:cd00751 1 VIVSAVRTPIGRFGGALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNPARQAALLAGLPESVPATTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 88 NRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISILTWPEGPYHNGITAENVA 167
Cdd:cd00751 81 NRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYLLPKARRGGRLGLNTLDGMLDDGLTDPFTGLSMGITAENVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 168 QRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATrLFATDEHPR-DTPREKLAALRPAFKADGVVTAA 246
Cdd:cd00751 161 EKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVPGRKGPV-VVDRDEGPRpDTTLEKLAKLKPAFKKDGTVTAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 247 NSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQAL 326
Cdd:cd00751 240 NASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINEAFAAQAL 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490207011 327 AVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:cd00751 320 ACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGGRYGLATMCIGGGQGAAMVIER 386
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
5-393 |
0e+00 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 520.48 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTA 84
Cdd:PRK05790 2 KDVVIVSAARTPIGKFGGALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQNPARQAALKAGLPVEVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLI-SILTWPEGPYHNGITA 163
Cdd:PRK05790 82 LTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQAPHVLPGSRWGQKMGDVELVDTMIhDGLTDAFNGYHMGITA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 164 ENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPAFKADGV 242
Cdd:PRK05790 162 ENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIKQRKGDPVVVDTDEHPRpDTTAESLAKLRPAFDKDGT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 243 VTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFA 322
Cdd:PRK05790 242 VTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDLIEINEAFA 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490207011 323 AQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK05790 322 AQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGAKKGLATLCIGGGQGVALIVER 392
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
4-393 |
7.37e-165 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 467.51 E-value: 7.37e-165
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 4 ANDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQI-AESGFIARICQLRAGIPQES 82
Cdd:PRK09051 2 MREVVVVSGVRTAIGTFGGSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTePRDMYLSRVAAINAGVPQET 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 83 TAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISILTWPEGPYHNGIT 162
Cdd:PRK09051 82 PAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSRAPYLLPAARWGARMGDAKLVDMMVGALHDPFGTIHMGVT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 163 AENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPdGKKATRLFATDEHPR-DTPREKLAALRPAFKAD- 240
Cdd:PRK09051 162 AENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPVEIK-TRKGEVVFDTDEHVRaDTTLEDLAKLKPVFKKEn 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 241 GVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEA 320
Cdd:PRK09051 241 GTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLTVADLDVIEANEA 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490207011 321 FAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK09051 321 FAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGGRYALVTMCIGGGQGIAAIFER 393
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
9-392 |
1.46e-164 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 466.32 E-value: 1.46e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 9 VVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSVN 88
Cdd:TIGR01930 1 IVAAARTPIGKFGGSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQQNIARQAALLAGLPESVPAYTVN 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 89 RQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYL-RKARDGYRMGHGELEDGLISILTWPEGPYHNGITAENVA 167
Cdd:TIGR01930 81 RQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRVPYGVpRSLRWGVKPGNAELEDARLKDLTDANTGLPMGVTAENLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 168 QRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATrLFATDEHPR-DTPREKLAALRPAFKADGVVTAA 246
Cdd:TIGR01930 161 KKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVKGRKGPV-TVSSDEGIRpNTTLEKLAKLKPAFDPDGTVTAG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 247 NSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQAL 326
Cdd:TIGR01930 240 NSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINEAFAAQVL 319
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490207011 327 AVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:TIGR01930 320 ACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGGRYGLATMCIGGGQGAAVILE 385
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
6-393 |
3.95e-137 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 397.44 E-value: 3.95e-137
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAY 85
Cdd:PRK06205 3 DAVICEPVRTPVGRFGGAFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIGRVAALDAGLPVTVPGM 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 86 SVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISILTWPeGPYHNGI---- 161
Cdd:PRK06205 83 QLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSNVEFYTTDMRWGVRGGGVQLHDRLARGRETA-GGRRFPVpggm 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 162 --TAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRP--- 235
Cdd:PRK06205 162 ieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTVPQRKGDPTVVDRDEHPRaDTTLESLAKLRPimg 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 236 AFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLI 315
Cdd:PRK06205 242 KQDPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGLTLDDIDLI 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 316 ELNEAFAAQALAVMNDLRLDPA---RVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK06205 322 ELNEAFAAQVLAVLKEWGFGADdeeRLNVNGSGISLGHPVGATGGRILATLLRELQRRQARYGLETMCIGGGQGLAAVFE 401
|
.
gi 490207011 393 R 393
Cdd:PRK06205 402 R 402
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
5-393 |
1.14e-127 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 373.07 E-value: 1.14e-127
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTA 84
Cdd:PRK05656 2 QDVVIVAATRTAIGSFQGSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQNPARQAAIKAGLPHSVPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISILTWPE-GPYHNGITA 163
Cdd:PRK05656 82 MTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPYVLPGARTGLRMGHAQLVDSMITDGLWDAfNDYHMGITA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 164 ENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPAFKADGV 242
Cdd:PRK05656 162 ENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITPILIPQRKGEPLAFATDEQPRaGTTAESLAKLKPAFKKDGS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 243 VTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFA 322
Cdd:PRK05656 242 VTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAELDLIEANEAFA 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490207011 323 AQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK05656 322 AQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRRDAKKGLATLCIGGGQGVALAIER 392
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
1-393 |
1.07e-122 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 360.81 E-value: 1.07e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQAndiVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIAR-AGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGI 78
Cdd:PRK09050 1 MTEA---FICDAIRTPIGRYGGALSSVRADDLGAVPLKALMARnPGVDWEAVDDVIYGCANQAGEDNRnVARMSALLAGL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 79 PQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMgHGELEDGLISiltW----PE 154
Cdd:PRK09050 78 PVSVPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRAPFVMGKADSAFSR-QAEIFDTTIG---WrfvnPL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 155 GPYHNGI-----TAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPRE 228
Cdd:PRK09050 154 MKAQYGVdsmpeTAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTIPQKKGDPVVVDRDEHPRpETTLE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 229 KLAALRPAFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMD 308
Cdd:PRK09050 234 ALAKLKPVFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRARILGMATAGVEPRIMGIGPAPATRKLLARLGLT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 309 VHAIDLIELNEAFAAQALAVMNDLRL--DPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQG 386
Cdd:PRK09050 314 IDQFDVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGGRYALCTMCIGVGQG 393
|
....*..
gi 490207011 387 ISMLFER 393
Cdd:PRK09050 394 IALAIER 400
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
8-392 |
3.25e-115 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 341.31 E-value: 3.25e-115
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 8 VVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSV 87
Cdd:PRK08235 5 VIVSAARTPFGKFGGSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGGQGQIPSRQAARAAGIPWEVQTETV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 88 NRQCGSGLQA--LADGMmqLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLI-SILTWPEGPYHNGITAE 164
Cdd:PRK08235 85 NKVCASGLRAvtLADQI--IRAGDASVIVAGGMESMSNAPYILPGARWGYRMGDNEVIDLMVaDGLTCAFSGVHMGVYGG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 165 NVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPAFKADGVV 243
Cdd:PRK08235 163 EVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTIPQRKGDPIVVAKDEAPRkDTTIEKLAKLKPVFDKTGTI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 244 TAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAA 323
Cdd:PRK08235 243 TAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEINEAFAA 322
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490207011 324 QALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK08235 323 VALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGGIGIAAICSGGGQGDAVLIE 391
|
|
| pcaF |
TIGR02430 |
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, ... |
5-393 |
8.39e-114 |
|
3-oxoadipyl-CoA thiolase; Members of this family are designated beta-ketoadipyl CoA thiolase, an enzyme that acts at the end of pathways for the degradation of protocatechuate (from benzoate and related compounds) and of phenylacetic acid.
Pssm-ID: 131483 Cd Length: 400 Bit Score: 337.91 E-value: 8.39e-114
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIAR-AGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGIPQES 82
Cdd:TIGR02430 1 REAYICDAIRTPIGRYGGSLSSVRADDLAAVPIKALLARnPQLDWAAIDDVIYGCANQAGEDNRnVARMAALLAGLPVSV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 83 TAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHgELEDGLIS-------------I 149
Cdd:TIGR02430 81 PGTTVNRLCGSGLDAIGMAARAIKAGEADLLIAGGVESMSRAPFVMGKADSAFSRSA-KIEDTTIGwrfinplmkalygV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 150 LTWPEgpyhngiTAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPRE 228
Cdd:TIGR02430 160 DSMPE-------TAENVAEEFGISREDQDAFALRSQQRTAAAQASGFFAEEIVPVVIPQKKGEPTVVDQDEHPRpETTLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 229 KLAALRPAFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMD 308
Cdd:TIGR02430 233 GLAKLKPVVRPDGTVTAGNASGVNDGAAALLLASEEAVQRHGLTPRARILAAATAGVEPRIMGIGPVPATQKLLARAGLS 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 309 VHAIDLIELNEAFAAQALAVMNDLRL--DPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQG 386
Cdd:TIGR02430 313 IDQFDVIELNEAFAAQALAVLRELGLadDDARVNPNGGAIALGHPLGASGARLVLTALRQLERSGGRYALCTMCIGVGQG 392
|
....*..
gi 490207011 387 ISMLFER 393
Cdd:TIGR02430 393 IALAIER 399
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
5-393 |
2.82e-112 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 333.47 E-value: 2.82e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIG-TFNGSLKHTHQHDLGAAVIREAIAR-AGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGIPQE 81
Cdd:PRK08947 2 EDVVIVDAIRTPMGrSKGGAFRNVRAEDLSAHLMRSLLARnPALDPAEIDDIIWGCVQQTLEQGFnIARNAALLAGIPHS 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 82 STAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPyylrkardgyrMGHG-ELEDGLISILTWPEGPYhnG 160
Cdd:PRK08947 82 VPAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVP-----------MNHGvDFHPGLSKNVAKAAGMM--G 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 161 ITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPAFK- 238
Cdd:PRK08947 149 LTAEMLGKMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGHDADGVLKLFDYDEVIRpETTVEALAALRPAFDp 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 239 ADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELN 318
Cdd:PRK08947 229 VNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELN 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490207011 319 EAFAAQALAVMNDLRLDPA---RVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK08947 309 EAFAAQSLPCLKDLGLLDKmdeKVNLNGGAIALGHPLGCSGARISTTLLNLMERKDAQFGLATMCIGLGQGIATVFER 386
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
8-393 |
2.29e-111 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 331.33 E-value: 2.29e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 8 VVVSGVRTAIGTFN-GSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGIPQESTAY 85
Cdd:PRK07661 5 VIVAGARTPVGKAKkGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLnMARNIGALAGLPYTVPAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 86 SVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYylrkardgyrMGHgELEDGLISILTWPEGPYHNGITAEN 165
Cdd:PRK07661 85 TINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSLVPM----------MGH-VVRPNPRLVEAAPEYYMGMGHTAEQ 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 166 VAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEV------PDGK--KATRLFATDEHPR-DTPREKLAALRPA 236
Cdd:PRK07661 154 VAVKYGISREDQDAFAVRSHQRAAKALAEGKFADEIVPVDVtlrtvgENNKlqEETITFSQDEGVRaDTTLEILGKLRPA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 237 FKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIE 316
Cdd:PRK07661 234 FNVKGSVTAGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFE 313
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490207011 317 LNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK07661 314 LNEAFASQSIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNEQFGIVTMCIGGGMGAAGVFEL 390
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
1-393 |
5.96e-111 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 330.81 E-value: 5.96e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQANDIVVVSGVRTAIGTF-NGSLKHTHQHDLGAAVIREAIARA-GLAPQDIDETIVGNVGQIAESGF-IARICQLRAG 77
Cdd:PRK09052 2 SKQLQDAYIVAATRTPVGKApRGMFKNTRPDDLLAHVLRSAVAQVpGLDPKLIEDAIVGCAMPEAEQGLnVARIGALLAG 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 78 IPQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYylrkardgyrMGHGE-------LEDGLISIl 150
Cdd:PRK09052 82 LPNSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSMVPM----------MGNKPsmspaifARDENVGI- 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 151 twpegPYHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEV----PDGKK-----ATRLFATDEH 221
Cdd:PRK09052 151 -----AYGMGLTAEKVAEQWKVSREDQDAFALESHQKAIAAQQAGEFKDEITPYEIterfPDLATgevdvKTRTVDLDEG 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 222 PR-DTPREKLAALRPAFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRR 300
Cdd:PRK09052 226 PRaDTSLEGLAKLKPVFANKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 301 LMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMC 380
Cdd:PRK09052 306 ALKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNLKYGMVTMC 385
|
410
....*....|...
gi 490207011 381 IGGGQGISMLFER 393
Cdd:PRK09052 386 VGTGMGAAGIFER 398
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
1-393 |
2.79e-104 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 313.18 E-value: 2.79e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQAndiVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQI-AESGFIARICQLRAGIP 79
Cdd:PRK07801 1 MAEA---YIVDAVRTPVGKRKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIgPQAGNIARTSWLAAGLP 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 80 QESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYylrkardGYRMGHGElEDGLISILTWPEG---- 155
Cdd:PRK07801 78 EEVPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPI-------SSAMTAGE-QLGFTSPFAESKGwlhr 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 156 ----PYHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVpdgkkatrlFATDEHPRDTPREKLA 231
Cdd:PRK07801 150 ygdqEVSQFRGAELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG---------VTVDEGPRETSLEKMA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 232 ALRPAFKaDGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHA 311
Cdd:PRK07801 221 GLKPLVE-GGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKTGLSIDD 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 312 IDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLF 391
Cdd:PRK07801 300 IDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGGRYGLQTMCEGGGTANVTII 379
|
..
gi 490207011 392 ER 393
Cdd:PRK07801 380 ER 381
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
14-392 |
5.66e-99 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 300.02 E-value: 5.66e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 14 RTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSVNRQCGS 93
Cdd:PRK06633 12 RTAFGSFMGSLSTTPAPMLAAHLIKDILQNSKIDPALVNEVILGQVITGGSGQNPARQTLIHAGIPKEVPGYTINKVCGS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 94 GLQALADGMMQLQSGQAEVVVACGTENMTqLPYYLRKARDGYRMGHGEL-----EDGLISILTwpeGPYHnGITAENVAQ 168
Cdd:PRK06633 92 GLKSVALAANSIMTGDNEIVIAGGQENMS-LGMHGSYIRAGAKFGDIKMvdlmqYDGLTDVFS---GVFM-GITAENISK 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 169 RFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDgKKATRLFATDEHPR-DTPREKLAALRPAFKADGVVTAAN 247
Cdd:PRK06633 167 QFNISRQEQDEFALSSHKKAAKAQLAGIFKDEILPIEVTI-KKTTSLFDHDETVRpDTSLEILSKLRPAFDKNGVVTAGN 245
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 248 SSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALA 327
Cdd:PRK06633 246 ASSINDGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEAFAAQSIY 325
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490207011 328 VMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK06633 326 VNREMKWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGLRRAKAKKGLVTLCIGGGMGMAMCVE 390
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
6-393 |
1.79e-98 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 298.55 E-value: 1.79e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNV-----GQIAesgfiARICQLRAGIPQ 80
Cdd:PLN02644 2 DVCIVGVARTPIGGFLGSLSSLSATELGSIAIQAALERAGVDPALVQEVFFGNVlsanlGQAP-----ARQAALGAGLPP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 81 ESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISILTW-PEGPYHN 159
Cdd:PLN02644 77 STICTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSNAPKYLPEARKGSRLGHDTVVDGMLKDGLWdVYNDFGM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 160 GITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGK-KATRLFATDEHPRDTPREKLAALRPAFK 238
Cdd:PLN02644 157 GVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEVPGGRgRPSVIVDKDEGLGKFDPAKLRKLRPSFK 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 239 AD-GVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIEL 317
Cdd:PLN02644 237 EDgGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGLEASQVDYYEI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490207011 318 NEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PLN02644 317 NEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNGKYGVAGICNGGGGASAIVVEL 392
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
31-394 |
2.33e-97 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 295.86 E-value: 2.33e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVGQIAES-GFIARICQLRAGIPQESTAYSVNRQCGSGLQALADGMMQLQSGQ 109
Cdd:PRK06445 34 ELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENwLYGGRHPIFLARLPYNIPAMAVDRQCASSLTTVSIGAMEIATGM 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 110 AEVVVACGTENMTQLPyylrkardgyrMGHGELEDGLISILTWPEGPYHN-------GITAENVAQRFGITREAMDDFAW 182
Cdd:PRK06445 114 ADIVIAGGVEHMTRTP-----------MGDNPHIEPNPKLLTDPKYIEYDlttgyvmGLTAEKLAEEAGIKREEMDRWSL 182
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 183 SSQQKALKAIAEDRFREQILALEVP-DGKKATrlFATDEHPR-DTPREKLAALRPAFKADGVVTAANSSGINDGAAALVM 260
Cdd:PRK06445 183 RSHQLAAKAIQEGYFKDEILPIEVEvEGKKKV--VDVDQSVRpDTSLEKLAKLPPAFKPDGVITAGNSSPLNSGASYVLL 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 261 MTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVN 340
Cdd:PRK06445 261 MSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLDPETVN 340
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 490207011 341 VNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFERE 394
Cdd:PRK06445 341 IKGGAIAIGHPLGATGARIVGTLARQLQIKGKDYGVATLCVGGGQGGAVVLERV 394
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
4-396 |
4.06e-97 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 297.06 E-value: 4.06e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 4 ANDIVVVSGVRTAI-GTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVgqIAESGFIA---RICQLRAGIP 79
Cdd:PLN02287 45 GDDVVIVAAYRTPIcKAKRGGFKDTYPDDLLAPVLKAVVEKTGLNPSEVGDIVVGTV--LAPGSQRAnecRMAAFYAGFP 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 80 QESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLISIltwpegpyhn 159
Cdd:PLN02287 123 ETVPVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGVESMTTNPMAWEGGVNPRVESFSQAQDCLLPM---------- 192
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 160 GITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQIlaleVPDGKKATRLFATDEHPR----------DTPREK 229
Cdd:PLN02287 193 GITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFKDEI----VPVHTKIVDPKTGEEKPIvisvddgirpNTTLAD 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 230 LAALRPAFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDV 309
Cdd:PLN02287 269 LAKLKPVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLEL 348
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 310 HAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSG--ARTGLVTMCIGGGQGI 387
Cdd:PLN02287 349 DDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPLGATGARCVATLLHEMKRRGkdCRFGVVSMCIGTGMGA 428
|
....*....
gi 490207011 388 SMLFEREGA 396
Cdd:PLN02287 429 AAVFERGDS 437
|
|
| fadA |
TIGR02445 |
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA ... |
6-393 |
1.85e-95 |
|
fatty oxidation complex, beta subunit FadA; This subunit of the FadBA complex has acetyl-CoA C-acyltransferase (EC 2.3.1.16) activity, and is also known as beta-ketothiolase and fatty oxidation complex, beta subunit. This protein is almost always located adjacent to FadB (TIGR02437). The FadBA complex is the major complex active for beta-oxidation of fatty acids in E. coli. [Fatty acid and phospholipid metabolism, Degradation]
Pssm-ID: 131498 Cd Length: 385 Bit Score: 290.69 E-value: 1.85e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRTAIG-TFNGSLKHTHQHDLGAAVIREAIAR-AGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGIPQES 82
Cdd:TIGR02445 1 DVVIVDFGRTPMGrSKGGAFRNTRAEDLSAHLMSKLLARnPKVDPAEVEDIYWGCVQQTLEQGFnIARNAALLAQIPHTS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 83 TAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPyylrkardgyrMGHG-ELEDGLISILTWPEGPYhnGI 161
Cdd:TIGR02445 81 AAVTVNRLCGSSMQALHDAARAIMTGDADVCLVGGVEHMGHVP-----------MMHGvDFHPGMSLHVAKAAGMM--GL 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 162 TAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPAFK-A 239
Cdd:TIGR02445 148 TAEMLGKMHGISREQQDAFAARSHARAHAATQEGKFKNEIIPTQGHDADGFLKQFDYDEVIRpETTVESLAALRPAFDpK 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 240 DGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNE 319
Cdd:TIGR02445 228 NGTVTAGTSSALSDGASAMLVMSEQRANELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELNE 307
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490207011 320 AFAAQALAVMNDLRLDPA---RVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:TIGR02445 308 AFAAQALPCLKDLGLLDKmdeKVNLNGGAIALGHPLGCSGARISTTLLNLMEQKDATFGLATMCIGLGQGIATVFER 384
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
6-393 |
4.17e-94 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 287.83 E-value: 4.17e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAE-SGFIARICQLRAGIPQESTA 84
Cdd:PRK08131 3 DAYIYDGLRSPFGRHAGALASVRPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEdSRNVARNALLLAGLPVTVPG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMgHGELEDGLIS------ILTWPEGPYH 158
Cdd:PRK08131 83 QTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRAPFVMGKAESAFSR-DAKVFDTTIGarfpnpKIVAQYGNDS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 159 NGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKA-TRLFATDEHPR-DTPREKLAALRPA 236
Cdd:PRK08131 162 MPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEVPQGRKLpPKLVAEDEHPRpSSTVEALTKLKPL 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 237 FkADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIE 316
Cdd:PRK08131 242 F-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARAGLTLDDMDIIE 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490207011 317 LNEAFAAQALAVMNDLRL--DPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK08131 321 INEAFASQVLGCLKGLGVdfDDPRVNPNGGAIAVGHPLGASGARLALTAARELQRRGKRYAVVSLCIGVGQGLAMVIER 399
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
1-393 |
3.09e-93 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 285.36 E-value: 3.09e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQAndiVVVSGVRTAIG-TFNGSLKHTHQHDLGAAVIREAIARA-GLAPQDIDETIVGnVGQIA-ESGF-IARICQLRA 76
Cdd:PRK07851 1 MPEA---VIVSTARSPIGrAFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLG-CGLPGgEQGFnMARVVAVLL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 77 GIPQESTAySVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENM-------------TQLPYY-------LRKARDGYR 136
Cdd:PRK07851 77 GYDFLPGT-TVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVsrfakgnsdslpdTKNPLFaeaqartAARAEGGAE 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 137 MGHGELEDGLIsiltwPEGPYHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKkatrLF 216
Cdd:PRK07851 156 AWHDPREDGLL-----PDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLPDGT----VV 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 217 ATDEHPR-DTPREKLAALRPAFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPS 295
Cdd:PRK07851 227 STDDGPRaGTTYEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPV 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 296 PATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTG 375
Cdd:PRK07851 307 EASKQALARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDKTFG 386
|
410
....*....|....*...
gi 490207011 376 LVTMCIGGGQGISMLFER 393
Cdd:PRK07851 387 LETMCVGGGQGMAMVLER 404
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
2-392 |
3.53e-92 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 282.55 E-value: 3.53e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 2 TQANDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQE 81
Cdd:PRK06954 4 VDQDPIVIASAARTPMAAFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVLPAGQGQAPARQAALGAGLPLS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 82 STAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLRKARDGYRMGHGELEDGLIsiLTWPEGPYHNG- 160
Cdd:PRK06954 84 VGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPYLLPKARGGMRMGHGQVLDHMF--LDGLEDAYDKGr 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 161 ---ITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPdGKKATRLFATDEHPRDTPREKLAALRPAF 237
Cdd:PRK06954 162 lmgTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVA-GKKGDTVIDRDEQPFKANPEKIPTLKPAF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 238 KADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIEL 317
Cdd:PRK06954 241 SKTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRAAEVDLFEI 320
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490207011 318 NEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK06954 321 NEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGGKRGVASLCIGGGEATAMGIE 395
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
1-393 |
1.73e-91 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 281.00 E-value: 1.73e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQAndiVVVSGVRT--AIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGF-IARICQLRAG 77
Cdd:PRK08242 1 MTEA---YIYDAVRTprGKGKKDGSLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGAdIARTAVLAAG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 78 IPQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPyylrkardgyrMGhgelEDGLisilTWPEGPY 157
Cdd:PRK08242 78 LPETVPGVQINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMSRVP-----------MG----SDGG----AWAMDPS 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 158 HN--------GITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKatrLFATDEHPR-DTPRE 228
Cdd:PRK08242 139 TNfptyfvpqGISADLIATKYGFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPVKDQNGLT---ILDHDEHMRpGTTME 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 229 KLAALRPAFKADG---------------------VVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGA 287
Cdd:PRK08242 216 SLAKLKPSFAMMGemggfdavalqkypeverinhVHHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDP 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 288 EIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEM 367
Cdd:PRK08242 296 TIMLTGPVPATRKALAKAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDEL 375
|
410 420
....*....|....*....|....*.
gi 490207011 368 ARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK08242 376 ERRGKRTALITLCVGGGMGIATIIER 401
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
8-393 |
5.97e-91 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 278.91 E-value: 5.97e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 8 VVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAE-SGFIARICQLRAGIPQESTAYS 86
Cdd:PRK07850 5 VIVEAVRTPIGKRNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEqSNNITRTAWLHAGLPYHVGATT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 87 VNRQCGSGLQA--LADGMmqLQSGQAEVVVACGTENMTQLPYylrkardGYRMGHGEledGLISILTWPEGPYHNGITAE 164
Cdd:PRK07850 85 IDCQCGSAQQAnhLVAGL--IAAGAIDVGIACGVEAMSRVPL-------GANAGPGR---GLPRPDSWDIDMPNQFEAAE 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 165 NVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKA------TRLFATDEHPRDTPREKLAALRPAFK 238
Cdd:PRK07850 153 RIAKRRGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEgqptgeTRLVTRDQGLRDTTMEGLAGLKPVLE 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 239 aDGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELN 318
Cdd:PRK07850 233 -GGIHTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEIN 311
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490207011 319 EAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK07850 312 EAFASVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDKSTALITMCAGGALSTGTIIER 386
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
6-394 |
8.65e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 277.28 E-value: 8.65e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRT-------AIGTFNGSlkhthqhDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGI 78
Cdd:PRK08170 4 PVYIVDGARTpflkargGPGPFSAS-------DLAVAAGRALLNRQPFAPDDLDEVILGCAMPSPDEANIARVVALRLGC 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 79 PQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYLR--------------------KARDGYRMG 138
Cdd:PRK08170 77 GEKVPAWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMSHAPLLFSekmvrwlagwyaaksigqklAALGKLRPS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 139 HGELEDGLISILTWPEGPYHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREqILALEVPDGKkatrLFAT 218
Cdd:PRK08170 157 YLAPVIGLLRGLTDPVVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLKE-VVPLFDRDGK----FYDH 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 219 DEHPR-DTPREKLAALRPAF-KADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSP 296
Cdd:PRK08170 232 DDGVRpDSSMEKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGPVH 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 297 ATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDL-----------------RLDPARVNVNGGAIALGHPVGASGAIL 359
Cdd:PRK08170 312 AATPLLQRHGLTLEDLDLWEINEAFAAQVLACLAAWadeeycreqlgldgalgELDRERLNVDGGAIALGHPVGASGARI 391
|
410 420 430
....*....|....*....|....*....|....*
gi 490207011 360 PVKLMYEMARSGARTGLVTMCIGGGQGISMLFERE 394
Cdd:PRK08170 392 VLHLLHALKRRGTKRGIAAICIGGGQGGAMLLERV 426
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
1-392 |
1.70e-89 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 275.49 E-value: 1.70e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQAndiVVVSGVRTAIG-TFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVG-QIAESGFIARICQLRAGI 78
Cdd:PRK07108 1 MTEA---VIVSTARTPLAkSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANpEGATGANIARQIALRAGL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 79 PQESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENM--TQLPYYLRKARDGYRMGHGeledglisiltwPEGP 156
Cdd:PRK07108 78 PVTVPGMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESIscVQNEMNRHMLREGWLVEHK------------PEIY 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 157 YHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDG---KKATRLF------ATDEHPR-DTP 226
Cdd:PRK07108 146 WSMLQTAENVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPITVTAGvadKATGRLFtkevtvSADEGIRpDTT 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 227 REKLAALRPAFKAdGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLN 306
Cdd:PRK07108 226 LEGVSKIRSALPG-GVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAG 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 307 MDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQG 386
Cdd:PRK07108 305 LKVDDIDLWELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRGAKYVVVTMCIGGGQG 384
|
....*.
gi 490207011 387 ISMLFE 392
Cdd:PRK07108 385 AAGLFE 390
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
7-264 |
7.36e-89 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 269.17 E-value: 7.36e-89
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 7 IVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYS 86
Cdd:pfam00108 1 VVIVSAARTPFGSFGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPARQAALKAGIPDSAPAVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 87 VNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYL-RKARDGYRMGHGELEDGLI-SILTWPEGPYHNGITAE 164
Cdd:pfam00108 81 INKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAPYALpTDARSGLKHGDEKKHDLLIpDGLTDAFNGYHMGLTAE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 165 NVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPdGKKATRLFATDEHPR-DTPREKLAALRPAFKADGVV 243
Cdd:pfam00108 161 NVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVK-GRKGKPTVDKDEGIRpPTTAEPLAKLKPAFDKEGTV 239
|
250 260
....*....|....*....|.
gi 490207011 244 TAANSSGINDGAAALVMMTRQ 264
Cdd:pfam00108 240 TAGNASPINDGAAAVLLMSES 260
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
5-392 |
3.23e-81 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 254.16 E-value: 3.23e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTA 84
Cdd:PRK06366 2 KDVYIVSAKRTAIGKFGRSFSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQAAYHAGLPFGVTK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYL-RKARDG--------YRMGHGELEDGLISILTWPeg 155
Cdd:PRK06366 82 YTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPFLLpSDLRWGpkhllhknYKIDDAMLVDGLIDAFYFE-- 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 156 pyHNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDgkkatrlfaTDEHPRDTPREKLAALRP 235
Cdd:PRK06366 160 --HMGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFNDLD---------RDEGIRKTTMEDLAKLPP 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 236 AFKADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLI 315
Cdd:PRK06366 229 AFDKNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAPIPATRKLLEKQNKSIDYYDLV 308
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490207011 316 ELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK06366 309 EHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTRHMKTGLATLCHGGGGAHTLTLE 385
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
9-393 |
6.61e-79 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 248.10 E-value: 6.61e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 9 VVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGF-IARICQLRAGIPQESTAYSV 87
Cdd:PRK06504 6 IVAAARTAGGRKGGRLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATnVARNAVLASKLPESVPGTSI 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 88 NRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYL-----RKARDGYRMGHGELEdglisilTWPEGPYHNGIT 162
Cdd:PRK06504 86 DRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMTRVPMGSpstlpAKNGLGHYKSPGMEE-------RYPGIQFSQFTG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 163 AENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKATRLFATDEHPR-DTPREKLAALRPaFKADG 241
Cdd:PRK06504 159 AEMMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRADGSGEMHTVDEGIRfDATLEGIAGVKL-IAEGG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 242 VVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAF 321
Cdd:PRK06504 238 RLTAATASQICDGASGVMVVNERGLKALGVKPLARIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDIDLYEVNEAF 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490207011 322 AAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK06504 318 ASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGKRYGLQTMCEGGGMANVTIVER 389
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
5-392 |
3.39e-78 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 245.45 E-value: 3.39e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 5 NDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIReaIARAGLAPQdIDETIVGNVgqIAESGFIARICQLRAGIPQESTA 84
Cdd:PRK06690 1 NRAVIVEAKRTPIGKKNGMLKDYEVQQLAAPLLT--FLSKGMERE-IDDVILGNV--VGPGGNVARLSALEAGLGLHIPG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 85 YSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYYlRKARDGyrmghgeledglisiltwPE--GPYHNGIT 162
Cdd:PRK06690 76 VTIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPFQ-NRARFS------------------PEtiGDPDMGVA 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 163 AENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALevpDGkkatrlFATDEHPRDTPREKL-AALRPAFKADG 241
Cdd:PRK06690 137 AEYVAERYNITREMQDEYACLSYKRTLQALEKGYIHEEILSF---NG------LLDESIKKEMNYERIiKRTKPAFLHNG 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 242 VVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAF 321
Cdd:PRK06690 208 TVTAGNSCGVNDGACAVLVMEEGQARKLGYKPVLRFVRSAVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAF 287
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490207011 322 AAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:PRK06690 288 ASKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKREDMKYGIATLGIGGGIGLALLFE 358
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
1-394 |
5.14e-75 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 239.50 E-value: 5.14e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQANDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQ 80
Cdd:PRK08963 1 TRQGDRIAIVSGLRTPFAKQATAFHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVQMPEAPNIAREIVLGTGMNV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 81 ESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTQLPYY-----------LRKARD-GYRMGhgeledgLIS 148
Cdd:PRK08963 81 HTDAYSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGvskklaralvdLNKARTlGQRLK-------LFS 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 149 ILTW----PEGP----YHNGI----TAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKAtrlF 216
Cdd:PRK08963 154 RLRLrdllPVPPavaeYSTGLrmgdTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDEVMTAHVPPYKQP---L 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 217 ATDEHPR-DTPREKLAALRPAF-KADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGA-EIMGFG 293
Cdd:PRK08963 231 EEDNNIRgDSTLEDYAKLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVwQDMLLG 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 294 PSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDL-----------------RLDPARVNVNGGAIALGHPVGASG 356
Cdd:PRK08963 311 PAYATPLALERAGLTLADLTLIDMHEAFAAQTLANLQMFaserfareklgrsqaigEVDMSKFNVLGGSIAYGHPFAATG 390
|
410 420 430
....*....|....*....|....*....|....*...
gi 490207011 357 AILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFERE 394
Cdd:PRK08963 391 ARMITQTLHELRRRGGGLGLTTACAAGGLGAAMVLEVE 428
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
6-393 |
1.06e-73 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 235.44 E-value: 1.06e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 6 DIVVVSGVRTAIG---TFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQI-AESGFIARICQLRAGIPQE 81
Cdd:PRK06025 3 EAYIIDAVRTPRGigkVGKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRgKQGGDLGRMAALDAGYDIK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 82 STAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMT-QLPYYLRKARDG---YRMGHGELEdglisiLTWPEGPY 157
Cdd:PRK06025 83 ASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSyTAAMAAEDMAAGkppLGMGSGNLR------LRALHPQS 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 158 HNGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALEVPDGKKAtrlFATDEHPR-DTPREKLAALRPA 236
Cdd:PRK06025 157 HQGVCGDAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPVYRDDGSVA---LDHEEFPRpQTTAEGLAALKPA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 237 FKA--------------------------DGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAEIM 290
Cdd:PRK06025 234 FTAiadyplddkgttyrglinqkypdleiKHVHHAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLM 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 291 GFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGHPVGASGAILPVKLMYEMARS 370
Cdd:PRK06025 314 LNAPVPAAKKVLAKAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELERR 393
|
410 420
....*....|....*....|...
gi 490207011 371 GARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK06025 394 GLKRGLVTMCAAGGMAPAIIIER 416
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
10-392 |
3.17e-59 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 197.33 E-value: 3.17e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 10 VSGVRTAIGTFNGSLK---HTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYS 86
Cdd:cd00826 1 AGAAMTAFGKFGGENGadaNDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVLGAGEGQNCAQQAAMHAGGLQEAPAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 87 VNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMTqlpyylrkardgyrmghgeledglisiltwpegpyhngITAENV 166
Cdd:cd00826 81 MNNLCGSGLRALALAMQLIAGGDANCILAGGFEKME--------------------------------------TSAENN 122
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 167 AQRFGI--------TREAMDDFAWSSQQKALKAIAEDRFREQILALEVpDGKKATRLFATDEHPR---DTPREKLAALRP 235
Cdd:cd00826 123 AKEKHIdvlinkygMRACPDAFALAGQAGAEAAEKDGRFKDEFAKFGV-KGRKGDIHSDADEYIQfgdEASLDEIAKLRP 201
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 236 AFKADGVVTAANSSGINDGAAALVMMTRQ-------QAEQRGLTPRMRIRGWAVAG----CGAEIMGFGPSPATRRLMDR 304
Cdd:cd00826 202 AFDKEDFLTAGNACGLNDGAAAAILMSEAeaqkhglQSKAREIQALEMITDMASTFedkkVIKMVGGDGPIEAARKALEK 281
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 305 LNMDVHAIDLIELNEAFAAQALAVMNDLRLDPAR------------------VNVNGGAIALGHPVGASGAILPVKLMYE 366
Cdd:cd00826 282 AGLGIGDLDLIEAHDAFAANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFE 361
|
410 420 430
....*....|....*....|....*....|.
gi 490207011 367 M-----ARSGARTGLVTMCIGGGQGISMLFE 392
Cdd:cd00826 362 LkgeagKRQGAGAGLALLCIGGGGGAAMCIE 392
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
271-393 |
1.34e-50 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 165.89 E-value: 1.34e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 271 LTPRMRIRGWAVAGCGAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMNDLRLDPARVNVNGGAIALGH 350
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 490207011 351 PVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGGKYGLASLCIGGGQGVAMIIER 123
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
1-393 |
2.18e-39 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 145.43 E-value: 2.18e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 1 MTQANDIVVVSGVRTAIGTFNGSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQ 80
Cdd:PRK09268 3 MPTVRRVAILGGNRIPFARSNGAYADASNQDMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNLTRECVLGSALSP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 81 ESTAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGT-----------ENMTQLPYYLRKARD---------GYRMGH- 139
Cdd:PRK09268 83 YTPAYDLQQACGTGLEAAILVANKIALGQIDSGIAGGVdttsdapiavnEGLRKILLELNRAKTtgdrlkalgKLRPKHl 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 140 -------GELEDGLiSIltwpegpyhnGITAENVAQRFGITREAMDDFAWSSQQKALKAIAEDRFREQILALevpdgKKA 212
Cdd:PRK09268 163 apeiprnGEPRTGL-SM----------GEHAAITAKEWGISREAQDELAAASHQNLAAAYDRGFFDDLITPF-----LGL 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 213 TRlfatDEHPR-DTPREKLAALRPAF--KADGVVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGC---- 285
Cdd:PRK09268 227 TR----DNNLRpDSSLEKLAKLKPVFgkGGRATMTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAETAAVdfvh 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 286 GAEIMGFGPSPATRRLMDRLNMDVHAIDLIELNEAFAAQALAVM----------NDLRL-------DPARVNVNGGAIAL 348
Cdd:PRK09268 303 GKEGLLMAPAYAVPRLLARNGLTLQDFDFYEIHEAFASQVLATLkawedeeycrERLGLdaplgsiDRSKLNVNGSSLAA 382
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 490207011 349 GHPVGASGAILPVKLMYEMARSGARTGLVTMCIGGGQGISMLFER 393
Cdd:PRK09268 383 GHPFAATGGRIVATLAKLLAEKGSGRGLISICAAGGQGVTAILER 427
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
30-390 |
1.61e-20 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 91.94 E-value: 1.61e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 30 HDLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPqESTAYSVNRQCGSGLQALADGMMQLQSGQ 109
Cdd:cd00829 17 LELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLL-GKPATRVEAAGASGSAAVRAAAAAIASGL 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 110 AEVVVACGTENMTQLPYylrkaRDGYRMGHGELEdglisiltWPEGPYHNGITAENVA--------QRFGITREAMDDFA 181
Cdd:cd00829 96 ADVVLVVGAEKMSDVPT-----GDEAGGRASDLE--------WEGPEPPGGLTPPALYalaarrymHRYGTTREDLAKVA 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 182 WSSQQKAL---KAIaedrFREQILALEVpdgkKATRLFAtdehprdtpreklaalrpafkadGVVTAANSSGINDGAAAL 258
Cdd:cd00829 163 VKNHRNAArnpYAQ----FRKPITVEDV----LNSRMIA-----------------------DPLRLLDCCPVSDGAAAV 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 259 VMMTRQQAEQRGLTPrMRIRGWAVAGCGAEIM----GFGPSP---ATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMND 331
Cdd:cd00829 212 VLASEERARELTDRP-VWILGVGAASDTPSLSerddFLSLDAarlAARRAYKMAGITPDDIDVAELYDCFTIAELLALED 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 332 LRLDP-------------AR-----VNVNGGAIALGHPVGASGailpVKLMYEMAR-----------SGARTGLVTMCIG 382
Cdd:cd00829 291 LGFCEkgeggklvregdtAIggdlpVNTSGGLLSKGHPLGATG----LAQAVEAVRqlrgeagarqvPGARVGLAHNIGG 366
|
....*...
gi 490207011 383 GGQGISML 390
Cdd:cd00829 367 TGSAAVVT 374
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
242-390 |
1.84e-17 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 81.34 E-value: 1.84e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 242 VVTAANSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAGCGAE----IMGFGPSPATRRLMDRLNMDVHAIDLIEL 317
Cdd:cd00327 91 LAGGSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEA 170
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 318 NEAFAAQALAVMNDLRLDP---ARVNVNGGAIALGHPVGASGAILPVKLMYEM-------ARSGARTGLVTMCIGGGQGI 387
Cdd:cd00327 171 HGTGTPIGDAVELALGLDPdgvRSPAVSATLIMTGHPLGAAGLAILDELLLMLehefippTPREPRTVLLLGFGLGGTNA 250
|
...
gi 490207011 388 SML 390
Cdd:cd00327 251 AVV 253
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
31-356 |
1.34e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 62.22 E-value: 1.34e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGN------VGQIAESGFIARICQLrAGIPqestAYSVNRQCGSGLQALADGMMQ 104
Cdd:PRK06064 24 DLAVEAGLEALEDAGIDGKDIDAMYVGNmsaglfVSQEHIAALIADYAGL-APIP----ATRVEAACASGGAALRQAYLA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 105 LQSGQAEVVVACGTENMTQLPY-----YLRKARDG-YRMGHGeledglisiLTWPEGpyhNGITAENVAQRFGITREAMD 178
Cdd:PRK06064 99 VASGEADVVLAAGVEKMTDVPTpdateAIARAGDYeWEEFFG---------ATFPGL---YALIARRYMHKYGTTEEDLA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 179 DFAWSSQQKALK-AIAEdrFREQILALEVpdgkkatrlfatdehprdtpreklaaLRPAFKADGvVTAANSSGINDGAAA 257
Cdd:PRK06064 167 LVAVKNHYNGSKnPYAQ--FQKEITVEQV--------------------------LNSPPVADP-LKLLDCSPITDGAAA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 258 LVMMTRQQAEQRGLTPrMRIRGWAVAGCGA------EIMGFGPSP-ATRRLMDRLNMDVHAIDLIELNEAFAAQALAVMN 330
Cdd:PRK06064 218 VILASEEKAKEYTDTP-VWIKASGQASDTIalhdrkDFTTLDAAVvAAEKAYKMAGIEPKDIDVAEVHDCFTIAEILAYE 296
|
330 340 350 360
....*....|....*....|....*....|....*....|....
gi 490207011 331 DLR-------LDPAR-----------VNVNGGAIALGHPVGASG 356
Cdd:PRK06064 297 DLGfakkgegGKLARegqtyiggdipVNPSGGLKAKGHPVGATG 340
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
22-356 |
4.05e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 60.73 E-value: 4.05e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 22 GSLKHTHQHDLGAAVIREAIARAGLAPQDIDETIVGN-----VGQIAESGFIARICQLRAGIPqestAYSVNRQCGSGLQ 96
Cdd:PRK07516 15 GKLDAETLESLIVRVAREALAHAGIAAGDVDGIFLGHfnagfSPQDFPASLVLQADPALRFKP----ATRVENACATGSA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 97 ALADGMMQLQSGQAEVVVACGTENMTQLPY-----YLRKArdGYRMGHGELEDGLISILtwpegpyhnGITAENVAQRFG 171
Cdd:PRK07516 91 AVYAALDAIEAGRARIVLVVGAEKMTATPTaevgdILLGA--SYLKEEGDTPGGFAGVF---------GRIAQAYFQRYG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 172 itreamddfawsSQQKALKAIAEDRFREQIlalevpdgkkatrlfatdehprDTPrekLAALRPAFKADGVVTAANS--- 248
Cdd:PRK07516 160 ------------DQSDALAMIAAKNHANGV----------------------ANP---YAQMRKDLGFEFCRTVSEKnpl 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 249 ----------SGINDGAAALVMMTRQQAeqRGLTPRMRIRGWAVAG-----CGAEIMGF-GPSPATRRLMDRLNMDVHAI 312
Cdd:PRK07516 203 vagplrrtdcSLVSDGAAALVLADAETA--RALQRAVRFRARAHVNdflplSRRDPLAFeGPRRAWQRALAQAGVTLDDL 280
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490207011 313 DLIELNEAF------------------AAQALA---VMNDLRLDparVNVNGGAIALGHPVGASG 356
Cdd:PRK07516 281 SFVETHDCFtiaelieyeamglappgqGARAIRegwTAKDGKLP---VNPSGGLKAKGHPIGATG 342
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
31-383 |
6.82e-09 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 57.01 E-value: 6.82e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGN------VGQIAESGFIARICQLRAGIPqeSTAYSVnrQCGSGLQALADGMMQ 104
Cdd:PRK06289 28 DLTREVVDGTLAAAGVDADDIEVVHVGNffgelfAGQGHLGAMPATVHPALWGVP--ASRHEA--ACASGSVATLAAMAD 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 105 LQSGQAEVVVACGTENMTQLP------------YYLRKARDGYRMghgeledglisiltWPegpYHNGITAENVAQRFGI 172
Cdd:PRK06289 104 LRAGRYDVALVVGVELMKTVPgdvaaehlgaaaWTGHEGQDARFP--------------WP---SMFARVADEYDRRYGL 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 173 TREAmddfawssqqkaLKAIAEDRFREqilALEVPdgKKATRLFA-TDEHPRDTpreklAALRPAfkADGVVTAANSSGI 251
Cdd:PRK06289 167 DEEH------------LRAIAEINFAN---ARRNP--NAQTRGWAfPDEATNDD-----DATNPV--VEGRLRRQDCSQV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 252 NDGAAALVMMTRQQAEQ-RGLTPRMRIRGWA--VAGcgaeiMGFGPS-----------PATRRLM----DRLNMDVHAID 313
Cdd:PRK06289 223 TDGGAGVVLASDAYLRDyADARPIPRIKGWGhrTAP-----LGLEQKldrsagdpyvlPHVRQAVldayRRAGVGLDDLD 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 314 LIELNEAFAAQALAVMNDLRLDPA------------------RVNVNGGAIALGHPVGASGailpVKLMYEMARS----- 370
Cdd:PRK06289 298 GFEVHDCFTPSEYLAIDHIGLTGPgeswkaiengeiaiggrlPINPSGGLIGGGHPVGASG----VRMLLDAAKQvtgta 373
|
410
....*....|....*....
gi 490207011 371 ------GARTGLvTMCIGG 383
Cdd:PRK06289 374 gdyqveGAKTFG-TLNIGG 391
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
31-373 |
5.28e-07 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 51.18 E-value: 5.28e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGfiaricqlRAGIPQEST-------AYSVNRQCGSGLQALADGMM 103
Cdd:PRK06157 29 DLMVEAFLEALADAGIEPKDIDAAWFGTHYDEIGSG--------KSGTPLSRAlrlpnipVTRVENFCATGSEAFRGAVY 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 104 QLQSGQAEVVVACGTEnmtqlpyylrKARDGyrmGHGELEDGLISILTWPEGPYHN-----GITAENVAQRFGITRE--- 175
Cdd:PRK06157 101 AVASGAYDIALALGVE----------KLKDT---GYGGLPVANPGTLADMTMPNVTapgnfAQLASAYAAKYGVSREdlk 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 176 -AMDDFAWSSQQKALKaiaedrfreqilalevpdgkkatrlfatdeHPRdtpreklAALRPAFKADGVVTAA-------- 246
Cdd:PRK06157 168 rAMAHVSVKSHANGAR------------------------------NPK-------AHLRKAVTEEQVLKAPmiagplgl 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 247 -NSSGINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVA-GCGAEIMG----FGPSPATRRLMDR------LNMDVHAIDL 314
Cdd:PRK06157 211 fDCCGVSDGAAAAIVTTPEIARALGKKDPVYVKALQLAvSNGWELQYngwdGSYFPTTRIAARKayreagITDPREELSM 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 315 IELNEAFAAQALAVMNDLRLDPA------------------RVNVNGGAIALGHPVGASGailpVKLMYEM-----ARSG 371
Cdd:PRK06157 291 AEVHDCFSITELVTMEDLGLSERgqawrdvldgffdadgglPCQIDGGLKCFGHPIGASG----LRMLYEMylqllGRAG 366
|
..
gi 490207011 372 AR 373
Cdd:PRK06157 367 ER 368
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
30-356 |
9.60e-07 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 50.28 E-value: 9.60e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 30 HDLGAAVIREAIARAGLAPQDIDETIVGNV------GQIA--ESGFiaricqlrAGIPqestAYSVNRQCGSGLQALADG 101
Cdd:PRK08256 23 PDMAAEAGRAALADAGIDYDAVQQAYVGYVygdstsGQRAlyEVGM--------TGIP----IVNVNNNCSTGSTALFLA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 102 MMQLQSGQAEVVVACGTENMTqlPYYLRKA---RDGYRMGHGELEDGLISILTWPEGPYHNGITAENVAQRFGITREamd 178
Cdd:PRK08256 91 RQAVRSGAADCALALGFEQMQ--PGALGSVwddRPSPLERFDKALAELQGFDPAPPALRMFGGAGREHMEKYGTTAE--- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 179 DFAWSSqQKALKAIAED---RFR-----EQILAlevpdgkkATRLFAtdehprdtPREKLAALRPAfkadgvvtaanssg 250
Cdd:PRK08256 166 TFAKIG-VKARRHAANNpyaQFRdeytlEDVLA--------SPMIWG--------PLTRLQCCPPT-------------- 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 251 inDGAAALVMMTRQQAEQRGLTPRMRIRGWAV---------AGCGAEIMGFGPS-PATRRLMDRLNMDVHAIDLIELNEA 320
Cdd:PRK08256 215 --CGAAAAIVCSEEFARKHGLDRAVEIVAQAMttdtpstfdGRSMIDLVGYDMTrAAAQQVYEQAGIGPEDIDVVELHDC 292
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 490207011 321 FAAQALAVMNDLRLDPA----------------RVNVN--GGAIALGHPVGASG 356
Cdd:PRK08256 293 FSANELLTYEALGLCPEgeaekfiddgdntyggRWVVNpsGGLLSKGHPLGATG 346
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
37-369 |
1.08e-06 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 50.23 E-value: 1.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 37 IREAIARAGLAPQDIDETIVGNVG----QIAESGFIARICQLRAGIPqestaYSVNRQCGSGLQALADGMMQLQSGQAEV 112
Cdd:PRK12578 29 IKEALNDAGVSQTDIELVVVGSTAyrgiELYPAPIVAEYSGLTGKVP-----LRVEAMCATGLAASLTAYTAVASGLVDM 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 113 VVACGTENMTQLPYYLRKARDGyRMGHGELEDGLISIlTWPEgpYHNGITAENVAqRFGITREAMDDFAWSSQQKALKAi 192
Cdd:PRK12578 104 AIAVGVDKMTEVDTSTSLAIGG-RGGNYQWEYHFYGT-TFPT--YYALYATRHMA-VYGTTEEQMALVSVKAHKYGAMN- 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 193 AEDRFREQILALEV------------------PDGkKATRLFATDEHPRDtprekLAALRPAFkADGVVTAANSSGIND- 253
Cdd:PRK12578 178 PKAHFQKPVTVEEVlksraiswpiklldscpiSDG-SATAIFASEEKVKE-----LKIDSPVW-ITGIGYANDYAYVARr 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 254 ----GAAALVMMTRQQAEQRGLTPRmRIRGWAVAGCG--AEIMGFGPSPATRRlmdrlnmdVHAIDLIELNEAFAAQALA 327
Cdd:PRK12578 251 gewvGFKATQLAARQAYNMAKVTPN-DIEVATVHDAFtiAEIMGYEDLGFTEK--------GKGGKFIEEGQSEKGGKVG 321
|
330 340 350 360
....*....|....*....|....*....|....*....|..
gi 490207011 328 vmndlrldparVNVNGGAIALGHPVGASGailpVKLMYEMAR 369
Cdd:PRK12578 322 -----------VNLFGGLKAKGHPLGATG----LSMIYEITK 348
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
253-358 |
1.12e-05 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 46.97 E-value: 1.12e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 253 DGAAALVMMTRQQAEQRGLTPRMRIRGWAVAgCGAEIMGfGPSP-------ATRRLMDRLNMDVHAIDLI-------ELN 318
Cdd:PRK05952 210 EGGAILVLESAELAQKRGAKIYGQILGFGLT-CDAYHMS-APEPdgksaiaAIQQCLARSGLTPEDIDYIhahgtatRLN 287
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 490207011 319 EAFAAQALAvmndlRLDPARVNVNGGAIALGHPVGASGAI 358
Cdd:PRK05952 288 DQREANLIQ-----ALFPHRVAVSSTKGATGHTLGASGAL 322
|
|
| PRK12879 |
PRK12879 |
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed |
31-124 |
6.76e-05 |
|
3-oxoacyl-(acyl carrier protein) synthase III; Reviewed
Pssm-ID: 237245 [Multi-domain] Cd Length: 325 Bit Score: 44.47 E-value: 6.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPqESTAYSVNRQCGSGLQALADGMMQLQSGQA 110
Cdd:PRK12879 55 DLAIKAAERALARAGLDAEDIDLIIVATTTPDYLFPSTASQVQARLGIP-NAAAFDINAACAGFLYGLETANGLITSGLY 133
|
90
....*....|....
gi 490207011 111 EVVVACGTENMTQL 124
Cdd:PRK12879 134 KKVLVIGAERLSKV 147
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
32-358 |
8.72e-05 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 44.45 E-value: 8.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 32 LGAAVIREAIARAGLAPQDID---------------ETIVGNVGQIAESGF---------------IARICQLRAGIPQE 81
Cdd:cd00834 74 FALAAAEEALADAGLDPEELDperigvvigsgigglATIEEAYRALLEKGPrrvspffvpmalpnmAAGQVAIRLGLRGP 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 82 StaYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTENMtqlpyylrkardgyrmghgeledglisiltwpegpyhngi 161
Cdd:cd00834 154 N--YTVSTACASGAHAIGDAARLIRLGRADVVIAGGAEAL---------------------------------------- 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 162 taenvaqrfgITREAMDDFAwssqqkALKAIAEDRFreqilalevpDGKKATRLFATDehpRdtpreklaalrpafkaDG 241
Cdd:cd00834 192 ----------ITPLTLAGFA------ALRALSTRND----------DPEKASRPFDKD---R----------------DG 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 242 VVtaanssgINDGAAALVMMTRQQAEQRGLTPRMRIRGWAVAgCGAEIMGfGPSP-------ATRRLMDRLNMDVHAIDL 314
Cdd:cd00834 227 FV-------LGEGAGVLVLESLEHAKARGAKIYAEILGYGAS-SDAYHIT-APDPdgegaarAMRAALADAGLSPEDIDY 297
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 490207011 315 I-------ELNEAFAAQALAVMNDLRLDPARVNVNGGAIalGHPVGASGAI 358
Cdd:cd00834 298 InahgtstPLNDAAESKAIKRVFGEHAKKVPVSSTKSMT--GHLLGAAGAV 346
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
251-358 |
1.96e-04 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 43.14 E-value: 1.96e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 251 INDGAAALVMMTRQQAeqRGLTPR-MRIRGWAVAgcgAEIMGFGP-----SPATRRLMDRL-NMDVHAIDLIELNEAFAA 323
Cdd:PRK07937 204 ITDGAAAVVLAAGDRA--RELRERpAWITGIEHR---IESPSLGArdltrSPSTALAAEAAtGGDAGGVDVAELHAPFTH 278
|
90 100 110
....*....|....*....|....*....|....*.
gi 490207011 324 QALAVMNDLRL-DPARVNVNGGAIAlGHPVGASGAI 358
Cdd:PRK07937 279 QELILREALGLgDKTKVNPSGGALA-ANPMFAAGLE 313
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
31-124 |
4.66e-04 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 41.63 E-value: 4.66e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVG--QI--AESGFIARicqlRAGIPqESTAYSVNRQCGSGLQAL--ADGMMq 104
Cdd:COG0332 53 DLAVEAARKALEAAGIDPEDIDLIIVATVTpdYLfpSTACLVQH----KLGAK-NAAAFDINAACSGFVYALsvAAALI- 126
|
90 100
....*....|....*....|
gi 490207011 105 lQSGQAEVVVACGTENMTQL 124
Cdd:COG0332 127 -RSGQAKNVLVVGAETLSRI 145
|
|
| FabB |
COG0304 |
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary ... |
32-119 |
6.50e-04 |
|
3-oxoacyl-(acyl-carrier-protein) synthase [Lipid transport and metabolism, Secondary metabolites biosynthesis, transport and catabolism]; 3-oxoacyl-(acyl-carrier-protein) synthase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440073 [Multi-domain] Cd Length: 409 Bit Score: 41.62 E-value: 6.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 32 LGAAVIREAIARAGLAPQDID---------------ETIVGNVGQIAE-------------------SGFIARICQLRAG 77
Cdd:COG0304 74 YALAAAREALADAGLDLDEVDpdrtgviigsgigglDTLEEAYRALLEkgprrvspffvpmmmpnmaAGHVSIRFGLKGP 153
|
90 100 110 120
....*....|....*....|....*....|....*....|..
gi 490207011 78 ipqestAYSVNRQCGSGLQALADGMMQLQSGQAEVVVACGTE 119
Cdd:COG0304 154 ------NYTVSTACASGAHAIGEAYRLIRRGRADVMIAGGAE 189
|
|
| PRK06059 |
PRK06059 |
lipid-transfer protein; Provisional |
31-121 |
1.15e-03 |
|
lipid-transfer protein; Provisional
Pssm-ID: 180373 [Multi-domain] Cd Length: 399 Bit Score: 40.90 E-value: 1.15e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVGQIAESGFIARICQLRAGIPQESTAYSVNRQCGSGLQALADGMMQLQSGQA 110
Cdd:PRK06059 25 EYGVVAARAALADAGLDWRDVQLVVGADTIRNGYPGFVAGATFAQALGWNGAPVSSSYAACASGSQALQSARAQILAGLC 104
|
90
....*....|.
gi 490207011 111 EVVVACGTENM 121
Cdd:PRK06059 105 DVALVVGADTT 115
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
31-122 |
1.67e-03 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 40.22 E-value: 1.67e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 31 DLGAAVIREAIARAGLAPQDIDETIVGNVgqIAESGFIARICQLRA--GIPQeSTAYSVNRQCGSGLQAL--ADGMMqlQ 106
Cdd:cd00830 52 DLAVEAAKKALEDAGIDADDIDLIIVATS--TPDYLFPATACLVQArlGAKN-AAAFDINAACSGFLYGLstAAGLI--R 126
|
90
....*....|....*.
gi 490207011 107 SGQAEVVVACGTENMT 122
Cdd:cd00830 127 SGGAKNVLVVGAETLS 142
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
234-358 |
4.30e-03 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 38.96 E-value: 4.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207011 234 RPAFK-ADGVVTAAnssgindGAAALVMMTRQQAEQRGLTPRMRIRGWAV----AGCGAEIMGFGPSPATRRLMDRLNMD 308
Cdd:cd00828 218 RPFDEtRDGFVEAE-------GAGVLVLERAELALARGAPIYGRVAGTASttdgAGRSVPAGGKGIARAIRTALAKAGLS 290
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90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*..
gi 490207011 309 VHAIDLIEL-------NEAFAAQALAVMNDLRLDPARVNVNGGAIalGHPVGASGAI 358
Cdd:cd00828 291 LDDLDVISAhgtstpaNDVAESRAIAEVAGALGAPLPVTAQKALF--GHSKGAAGAL 345
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