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Conserved domains on  [gi|490207515|ref|WP_004105926|]
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MULTISPECIES: glycerone kinase [Klebsiella]

Protein Classification

dihydroxyacetone kinase family protein( domain architecture ID 1001500)

dihydroxyacetone kinase family protein similar to human triokinase/FMN cyclase and dihydroxyacetone kinase subunit L (DhaL), which is the ADP-binding subunit of dihydroxyacetone kinase that catalyzes the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone via a phosphoryl group transfer from DhaL-ATP

Gene Ontology:  GO:0004371|GO:0006071|GO:0005524
PubMed:  16505971|15476397

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14479 super family cl29418
dihydroxyacetone kinase; Provisional
 3-547 0e+00

dihydroxyacetone kinase; Provisional


The actual alignment was detected with superfamily member TIGR02361:

Pssm-ID: 475197 [Multi-domain]  Cd Length: 574  Bit Score: 623.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515    3 QFFFNQRANLVNEVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  158 VHKVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  237 VTLMVEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELANTPLH-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPRAISVMPSSLRSTRVEFTPS---ENSEVAGYVERVTGTLSNLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKREVVSSSAPELIEETAVrsyDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALLAEPENLQAAFAAAQAGADRTLHaSKAGAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 490207515  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 623.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515    3 QFFFNQRANLVNEVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  158 VHKVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  237 VTLMVEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELANTPLH-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPRAISVMPSSLRSTRVEFTPS---ENSEVAGYVERVTGTLSNLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKREVVSSSAPELIEETAVrsyDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALLAEPENLQAAFAAAQAGADRTLHaSKAGAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 490207515  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 1-547 7.96e-140

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 416.91  E-value: 7.96e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   1 MSQFFFNQRANLVNEVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375   2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375  78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 159 HKVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDaETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375 158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 239 LMVEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELANTpLHQRIDWLIG--PASLVTALDMKGFSL 305
Cdd:PTZ00375 237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQ-LAQAGLTVVGvhSGRLMTSLEMHGFSL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 306 TAIVLEESIEKALLSAVETA---------GWQTPVQPR-AISVMPSSLRSTRVEFTPSENSEVAGYVERVTGTLSNLEAD 375
Cdd:PTZ00375 316 TLLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLsALQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENY 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 376 LNALDAKVGDGDTGSTFAAGARDIADLLQrrQLPL-ANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA--- 451
Cdd:PTZ00375 396 LNELDAEVGDGDLGSGLERSSKAVLESLP--YLPLeANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALngg 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 452 ----SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALLAEPENLQAAFAAAQAGADRTLHAsKAGAG 518
Cdd:PTZ00375 474 navdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHG 552

                        570       580
                 ....*....|....*....|....*....
gi 490207515 519 RASYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375 553 RSRYLEGKEL-GKKDPGAELVVAWVEALA 580
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 18-326 1.21e-118

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 352.52  E-value: 1.21e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  174 TVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLMVEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490207515  253 -RLAVMINNLGGVSIAEMAILTRELANTpLHQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 5-201 1.29e-21

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 92.96  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   5 FFNQRANLVNEVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376   14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376   86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 490207515 160 kvagyFAErghNLATVLREAQYAARHTFSLGLALSSCHLPQD 201
Cdd:COG2376  139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
 
Name Accession Description Interval E-value
dak_ATP TIGR02361
dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of ...
 3-547 0e+00

dihydroxyacetone kinase, ATP-dependent; This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().


Pssm-ID: 274097 [Multi-domain]  Cd Length: 574  Bit Score: 623.25  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515    3 QFFFNQRANLVNEVIEGTIIASPWnnLARLESDpaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDL 82
Cdd:TIGR02361   1 KHFVNDPEHLVDDALKGLVAANPG--LQLLESR---KVVYRRDLNKDKVSLISGGGSGHEPAHAGFVGKGMLTAAVAGDV 75

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   83 FASPSVDAVLTAIQAVTG-DAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNK----HPRGIAGTIL 157
Cdd:TIGR02361  76 FASPSTKQILAAIRAVVGsEAGTLLIVKNYTGDRLNFGLAAEKAKAEGYNVEMVIVGDDVSVGRKKgglvGRRGLAGTVL 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  158 VHKVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAE-I 236
Cdd:TIGR02361 156 VHKIAGAAAARGLSLAEVAKVAQAAADNLVTIGASLDHCHVPGETEAEPELKEDEMELGMGIHNEPGAKRISPIPSSDlV 235

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  237 VTLMVEKLSA--------ALPETGRLAVMINNLGGVSIAEMAILT-RELANTPLH-QRIDWLIGPASLVTALDMKGFSLT 306
Cdd:TIGR02361 236 VQLMLKKLLDetdkrsyvKFNEGDEVVLLVNNLGGVSNLELGIIAdEVVEQLALHyNIIPVRIYSGTFMTSLNGPGFSIT 315

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  307 AIVLEE---SIEKALLSAVETAGW----QTPVQPRAISVMPSSLRSTRVEFTPS---ENSEVAGYVERVTGTLSNLEADL 376
Cdd:TIGR02361 316 LLNATEagkSILDLLDAPTEAPGWpvaaYSSKPWREKREVVSSSAPELIEETAVrsyDPQLVAAILESGCAALLELEPHL 395

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  377 NALDAKVGDGDTGSTFAAGARDIADLLQRRQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGAS---- 452
Cdd:TIGR02361 396 TKLDTKAGDGDCGSTLARGAEAILELLKSKKLPLNDPATLLAQISDVVEGVMGGTSGALYSIFFSAAAQSLKQNASkkee 475

                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  453 -----VAEALNAGLAQMKFYGGADEGDRTMIDALQPALAALLAEPENLQAAFAAAQAGADRTLHaSKAGAGRASYLNSDS 527
Cdd:TIGR02361 476 itpeaWAAALKTALDALYKYTGARPGDRTMIDALQPFVEALEAGKSNLNAAVKAAEAGAEATKK-MKAKAGRASYVSSEA 554

                         570       580
                  ....*....|....*....|
gi 490207515  528 LRGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02361 555 LEGVPDPGAVGLAAWLRGLA 574
PTZ00375 PTZ00375
dihydroxyacetone kinase-like protein; Provisional
 1-547 7.96e-140

dihydroxyacetone kinase-like protein; Provisional


Pssm-ID: 185583 [Multi-domain]  Cd Length: 584  Bit Score: 416.91  E-value: 7.96e-140
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   1 MSQFFFNQRANLVNEVIEGTIIASPwNNLARLESdpaIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCG 80
Cdd:PTZ00375   2 VSKKFINSPEKVVSEAVDGLCMTNN-DSLKRIEN---TNVVVRSDIDKTKVLLISGGGSGHEPAHAGFVGKGWLTAAVCG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  81 DLFASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDIS--LPDNKHPRGIAGTILV 158
Cdd:PTZ00375  78 SVFASPSTKHVLAAIEYVPNGPGCLLIVKNYTGDILNFELAVEQARARGIQVETVLVADDAAfgTKDIANRRGIAGTVLL 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 159 HKVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDaETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVT 238
Cdd:PTZ00375 158 YKILGAAAEKGASLTQLKKLADRISSNMRSIGVSLSSCSLPGN-DPSSTVPPGTMEVGLGIHGEKGLARIPFQGAKDLVK 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 239 LMVEKL-----------SAALPETGRLAVMINNLGGVSIAEMAILTRELANTpLHQRIDWLIG--PASLVTALDMKGFSL 305
Cdd:PTZ00375 237 FLIGILlgkgkkrgggkTTAIREGAKVALLVNNLGSTTDLEMSILAHHALRQ-LAQAGLTVVGvhSGRLMTSLEMHGFSL 315

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 306 TAIVLEESIEKALLSAVETA---------GWQTPVQPR-AISVMPSSLRSTRVEFTPSENSEVAGYVERVTGTLSNLEAD 375
Cdd:PTZ00375 316 TLLPIEDEDDLQLLDTNQKPllnfhtpqsSWATAKGPLsALQLAKPEAEAASRKAATPTNSLLRSVLERVFETLIESENY 395

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 376 LNALDAKVGDGDTGSTFAAGARDIADLLQrrQLPL-ANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGA--- 451
Cdd:PTZ00375 396 LNELDAEVGDGDLGSGLERSSKAVLESLP--YLPLeANVRKTLTLISKAVADAFGGSSGPLYGAFLLGGANALAEALngg 473

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 452 ----SVAEALNAGLAQMKFYGGADEGDRTMIDALQPAL---------AALLAEPENLQAAFAAAQAGADRTLHAsKAGAG 518
Cdd:PTZ00375 474 navdAVRAALAAGSHSIQELGGARVGDRTMVDVLIPFAealnscpsvNEAASSPELLKACSEEAREAAEATALL-PAKHG 552

                        570       580
                 ....*....|....*....|....*....
gi 490207515 519 RASYLNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:PTZ00375 553 RSRYLEGKEL-GKKDPGAELVVAWVEALA 580
PRK14479 PRK14479
dihydroxyacetone kinase; Provisional
 5-548 9.79e-129

dihydroxyacetone kinase; Provisional


Pssm-ID: 237723 [Multi-domain]  Cd Length: 568  Bit Score: 387.63  E-value: 9.79e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   5 FFNQRANLVNEVIEGTIIASPwnnlaRLESDPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14479   4 LINDPSTFVEEMLEGFVAAHP-----DLVRLVPGGVVRRTPTPEGKVAVVSGGGSGHEPAFAGYVGPGMLDAAVCGNVFT 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDNKHP--RGIAGTILVHKV 161
Cdd:PRK14479  79 SPSADQVYAAIRAADGGAGVLLIVGNYAGDVMNFGLAAELARAEGIDVRTVVVTDDVASaPSGETAgrRGIAGTVLVFKI 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 162 AGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPqdAETTPRHH--PDQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14479 159 AGAAAEAGLDLDEVAAIARKANARTRSMGVALDGCTLP--GAGEPLFTlpEGEMELGLGIHGEPGIEREALPTADELADR 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 240 MVEKLSAALPE--TGRLAVMINNLGGVSIAEMAILTRELANTpLHQR----IDWLIGpaSLVTALDMKGFSLTAIVLEES 313
Cdd:PRK14479 237 LVDRILADLPLgaGERVAVLVNGLGATPYEELFVVYGAVARL-LAARgitvVRPEVG--EFVTSLDMAGASLTLMKLDDE 313

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 314 IEKALLSAVETAGWqtPVQPRAISVMPSSLRS---TRVEFTPSENS-----EVAGYVERVTGTLSNLEADLNALDAKVGD 385
Cdd:PRK14479 314 LEELWDAPADTPAF--RRGGAVEPVEYVEAAEeddAEEPPRASKASrataaNLVAALDAVAEALIDNEDELGELDAVAGD 391

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 386 GDTGSTFAAGARDIADLLQRRQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEALNAG 460
Cdd:PRK14479 392 GDHGIGMARGSKAALAAARAAVEAGAGAGSVLAAAGDAWADHAGGTSGPLWGTALRAAGKALGDkdeptAADFAAAVRAA 471

                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 461 LAQMKFYGGADEGDRTMIDALQPALAALLAEPENLQAAFAAAQAGADRTLHASKAGA------GRASYLNSDSLrGNMDP 534
Cdd:PRK14479 472 VDAIQELGGAQVGDKTMVDALVPFADALEAAAAAGADLAEAWAAAAEAAEEGAEATAdlvprmGRARYLGERSL-GTPDA 550

                        570
                 ....*....|....
gi 490207515 535 GAHAVAMVFKALAQ 548
Cdd:PRK14479 551 GAVSLALIFTAIAG 564
Dak1 pfam02733
Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.
 18-326 1.21e-118

Dak1 domain; This is the kinase domain of the dihydroxyacetone kinase family EC:2.7.1.29.


Pssm-ID: 460667  Cd Length: 312  Bit Score: 352.52  E-value: 1.21e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   18 EGTIIASPwNNLARLESDpaiRVVVRRDL-DKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASPSVDAVLTAIQ 96
Cdd:pfam02733   1 EGLAAAHP-DLLRLVPGP---RVVVRADApPKGKVALISGGGSGHEPAHAGYVGKGMLDAAVPGEVFASPSPDQILAAIK 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   97 AVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVAGYFAERGHNLA 173
Cdd:pfam02733  77 AVDGGAGVLLIVKNYTGDVLNFGMAAELARAEGIKVETVVVGDDVAVGDSGGTvgrRGVAGTVLVHKIAGAAAEAGASLD 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  174 TVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLMVEKLSAALPETG- 252
Cdd:pfam02733 157 EVARLAEKVNANTRTMGVALSPCTVPGAGKPTFELGEDEMELGMGIHGEPGVKREKLKPADELVEELLDKLLDDDPLLPg 236

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490207515  253 -RLAVMINNLGGVSIAEMAILTRELANTpLHQR----IDWLIGPasLVTALDMKGFSLTAIVLEESIEKALLSAVETAG 326
Cdd:pfam02733 237 dEVAVLVNGLGGTPLLELYIVYRRVLEL-LEEKgikvVRSLVGE--YMTSLDMAGFSLTLLKLDDELLELLDAPVDTPA 312
PRK14481 PRK14481
dihydroxyacetone kinase subunit DhaK; Provisional
 5-327 3.20e-102

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 237724  Cd Length: 331  Bit Score: 311.36  E-value: 3.20e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   5 FFNQRANLVNEVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFA 84
Cdd:PRK14481   4 LINDPETVVDEMLEGLVAAHP--DLVTRIDDT--DVIVRKDKPPGKVALVSGGGSGHEPAHAGFVGEGMLDAAVCGAVFT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  85 SPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKV 161
Cdd:PRK14481  80 SPTPDQILEAIKAVDTGAGVLLIVKNYSGDVMNFEMAAELAEMEGIEVASVVVDDDVAVEDSLYTqgrRGVAGTVFVHKI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 162 AGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLMV 241
Cdd:PRK14481 160 AGAAAEAGASLDEVKALAEKVNPNIRSMGVALSPCTVPAVGKPGFDLGDDEIEIGIGIHGEPGRRREKLKPADEIAEELL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 242 EKLSAALPET--GRLAVMINNLGGVSIAEMAILTRELANTpLHQR----IDWLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:PRK14481 240 EKILEDLKLVagDEVLVLVNGMGATPLMELYIVYNDVAEL-LEERgvtvARSLVG--NYMTSLDMAGFSITLLKLDDELL 316

                        330
                 ....*....|..
gi 490207515 316 KALLSAVETAGW 327
Cdd:PRK14481 317 ELLDAPVDTPAL 328
dhaK1 TIGR02363
dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) ...
 5-327 1.97e-87

dihydroxyacetone kinase, DhaK subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the DhaK subunit of the latter type of dihydroxyacetone kinase, but it specifically excludes the DhaK paralog DhaK2 (TIGR02362) found in the same operon as DhaK and DhaK in the Firmicutes.


Pssm-ID: 274098  Cd Length: 329  Bit Score: 273.08  E-value: 1.97e-87
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515    5 FFNQRANLVNEVIEGTIIASPwnNLARLESDPaiRVVVRRDLDKNN-VAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:TIGR02363   4 LINDPEDVVAEMLDGLVKAHP--ELVTLVADT--RVIVRKDKKVNGkVALVSGGGSGHEPAHAGFVGYGMLDAAVPGEVF 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHK 160
Cdd:TIGR02363  80 TSPTPDQILEAIKAVDQGAGVLLIVKNYTGDVMNFEMAAELAEDEGIKVATVVVDDDIAVEDSLYTagrRGVAGTVFVHK 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  161 VAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLM 240
Cdd:TIGR02363 160 IAGAAAEKGASLDELKSLGEKVNPNTKSIGVALTACTVPAVGKPGFDLADDEMEIGVGIHGEPGIRREKMKSSDEIADEL 239

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  241 VEKL--SAALPETGRLAVMINNLGGVSIAEMAILTRELANTPLHQRID---WLIGpaSLVTALDMKGFSLTAIVLEESIE 315
Cdd:TIGR02363 240 LDKLldDLGLQSGDRVIVLVNGMGATPLMELYIFYNDVQRLLEQRGVNvarTLVG--NYMTSLDMAGFSLTLLKLDDELL 317

                         330
                  ....*....|..
gi 490207515  316 KALLSAVETAGW 327
Cdd:TIGR02363 318 ELWDAPVTTIAL 329
PRK14483 PRK14483
DhaKLM operon coactivator DhaQ; Provisional
 4-327 2.42e-70

DhaKLM operon coactivator DhaQ; Provisional


Pssm-ID: 172956  Cd Length: 329  Bit Score: 228.78  E-value: 2.42e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   4 FFFNQRANLVNEVIEGTIIASPwnNLARLesdPAIRVVVRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLF 83
Cdd:PRK14483   3 KIMNDVQNIVQDMLHGFYFAHP--NLDET---NNIPYVYDIEKDDQLVPIISGGGSGHEPAHIGYVGKGMLTAAVNGSIF 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  84 ASPSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPD----NKHPRGIAGTILVH 159
Cdd:PRK14483  78 TPPTAEQILAATRLVPKGKGVFFIIKNFEADVAEFSAAIQIARQEGRQIKYIIVHDDISVEDdasfNKRRRGVAGTVLLH 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 160 KVAGYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTL 239
Cdd:PRK14483 158 KILGAAALEGASLDELEQLGLSLTENIATLGVALSPANLPVAGLPSFDLNEDEISYGIGIHGEPGYRKEPFSSSEILAIE 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 240 MVEKLSAAL--PETGRLAVMINNLGGVSIAEMAILTR------ELANTPLHqridwLIGPASLVTALDMKGFSLTAIVLE 311
Cdd:PRK14483 238 LVNKLKSKYrwQKGDNFILLINGLGATTLMEQYIFANdirrllELEGLQIT-----FVKVGTLLTSLDMKGISLTLLKVK 312

                        330
                 ....*....|....*..
gi 490207515 312 ES-IEKALLSAVETAGW 327
Cdd:PRK14483 313 DPdWLDWLKAPTRAAAW 329
PRK11468 PRK11468
dihydroxyacetone kinase subunit DhaK; Provisional
 7-327 7.76e-66

dihydroxyacetone kinase subunit DhaK; Provisional


Pssm-ID: 183150  Cd Length: 356  Bit Score: 217.96  E-value: 7.76e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   7 NQRANLVNEVIEGTIIASPwnNLaRLESDPaiRVVVRRDLD-KNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFAS 85
Cdd:PRK11468   6 NDVEDVLDEQLAGLAKAHP--EL-TLHQDP--VYVTRADAPvAGKVALLSGGGSGHEPMHCGFVGQGMLDGACPGEIFTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  86 PSVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISLPDNKHP---RGIAGTILVHKVA 162
Cdd:PRK11468  81 PTPDQMFECAMQVDGGEGVLLIIKNYTGDVLNFETATELLHDSGVKVTTVLIDDDVAVKDSLYTagrRGVANTVLIEKLV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 163 GYFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLMVE 242
Cdd:PRK11468 161 GAAAERGYSLDQCAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIHGEPGIDRRPFSSLDQTVDEMFD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 243 KL--------------------------SAALPETGRLAVMINNLGGVSIAEMAILTRELANTPLHQRIDW---LIGPas 293
Cdd:PRK11468 241 TLlengsyhrtlrfwdrqqgswqeeeqtKQPLQSGDRVIALVNNLGATPLSELYGVYNRLATRCEQAGLTIernLIGA-- 318

                        330       340       350
                 ....*....|....*....|....*....|....
gi 490207515 294 LVTALDMKGFSLTAIVLEESIEKALLSAVETAGW 327
Cdd:PRK11468 319 YCTSLDMQGFSITLLKVDDETLALWDAPVHTPAL 352
dhaK1b TIGR02362
probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase ...
 7-327 3.91e-57

probable dihydroxyacetone kinase DhaK1b subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form with a phosphoprotein donor related to PTS transport proteins. This family represents a protein, unique to the Firmicutes (low GC Gram-positives), that appears to be a divergent second copy of the K subunit of that complex; its gene is always found in operons with the other three proteins of the complex.


Pssm-ID: 213706  Cd Length: 326  Bit Score: 193.86  E-value: 3.91e-57
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515    7 NQRANLVNEVIEGTIIASPwnNLARLESDPAIRvvvRRDLDKNNVAVISGGGSGHEPAHAGFVGKGMLTAAVCGDLFASP 86
Cdd:TIGR02362   4 NEPQNAVSQAIQGIQWAYP--NLVQVPDLPGIY---DSNFDDQQIPIISGGGSGHEPAHWGYVGEGMLSAAIMGDVFVPP 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   87 SVDAVLTAIQAVTGDAGCLLIVKNYTGDRLNFGLAAEKARRMGYNVEMLIVGDDISL-PDN--KHPRGIAGTILVHKVAG 163
Cdd:TIGR02362  79 TAQDILEAIRQVDRGKGVFVIIKNFEADLSEFSQAIQQARQEGRQIKYIIVHDDISVeHESfkQRRRGVAGTILVHKILG 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  164 YFAERGHNLATVLREAQYAARHTFSLGLALSSCHLPQDAETTPRHHPDQAELGMGIHGEPGASVIATQNSAEIVTLMVEK 243
Cdd:TIGR02362 159 AAAAEGASLDELEHIAAALVTNIATIGVAAKSARIPGQSTPSFDLEEGEIYYGIGIHGEPGYRTEPFVSSEHLAVELVNK 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  244 LSAAL--PETGRLAVMINNLGGVSIAEMAILT----RELANTPLHqrIDWlIGPASLVTALDMKGFSLTAIVL-EESIEK 316
Cdd:TIGR02362 239 LKLKFrwQADDHYAVLVNNLGGTTPMEQMVFNndvhELLALEALH--LPF-IKVGTFLTSLDMHGLSLTLLRLkDPQWLD 315

                         330
                  ....*....|.
gi 490207515  317 ALLSAVETAGW 327
Cdd:TIGR02362 316 YLNAPVDAAAW 326
Dak2 pfam02734
DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase ...
 382-548 4.53e-28

DAK2 domain; This domain is the predicted phosphatase domain of the dihydroxyacetone kinase family.


Pssm-ID: 460668 [Multi-domain]  Cd Length: 175  Bit Score: 110.35  E-value: 4.53e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  382 KVGDGDTGSTFAAGARDIADLLQrrQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ-----GASVAEA 456
Cdd:pfam02734   1 PVGDGDHGTNMARGFEAALKALE--DLEPASLAEVLKALAMALLSGAGGNSGPLYGQFFRGAAKALKGkeeldAEDLAAA 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  457 LNAGLAQMKFYGGADEGDRTMIDalqpALAALLAEPENLQAAFAAAQAGADRTLHASKAGA----------GRASYLNSD 526
Cdd:pfam02734  79 LEAALEAIQARGKARPGDKTMLD----VLRPAAEALEAAAEAGEDLAEALEAAVKAAEEGAeatkellaklGRASYLGER 154

                         170       180
                  ....*....|....*....|..
gi 490207515  527 SLrGNMDPGAHAVAMVFKALAQ 548
Cdd:pfam02734 155 SI-GVVDPGATGLALILEALLE 175
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 5-201 1.29e-21

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 92.96  E-value: 1.29e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515   5 FFNQRANLVNEVIEGTIIASPWNNLARL--ESDPAIRVVVRRDLDKnnVAVISGGGSGhepahaGFVGKGMLTAAVCGDL 82
Cdd:COG2376   14 FLNDLDAVVGDGDHGINMARGFDAVRAAldAAPADPGVVLRAAGMK--VASVVGGGSG------GLVGTGFLDAAVALKG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  83 FASPSVDAVLTAIQAVT---GDAGcllivKNYTGDRLNFGLAAEKARRMgynVEMLIVGDDislpdnkhprgiagtilvh 159
Cdd:COG2376   86 ETSPTADQVAAALRAADegiQGRG-----VAYTGDKTNFDAAAPAAEAI---EEAVAAGTA------------------- 138

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 490207515 160 kvagyFAErghNLATVLREAQYAARHTFSLGLALSSCHLPQD 201
Cdd:COG2376  139 -----AAA---ALDEAAAAAEKGAEATRSMGAALGRATYPGE 172
dha_L_ycgS TIGR02365
dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone ...
 373-547 1.69e-16

dihydroxyacetone kinase, phosphoprotein-dependent, L subunit; Two types of dihydroxyacetone kinase (glycerone kinase) are described. In yeast and a few bacteria, e.g. Citrobacter freundii, the enzyme is a single chain that uses ATP as phosphoryl donor and is designated EC 2.7.1.29. By contract, E. coli and many other bacterial species have a multisubunit form (EC 2.7.1.-) with a phosphoprotein donor related to PTS transport proteins. This family represents the subunit homologous to the E. coli YcgS subunit.


Pssm-ID: 274099 [Multi-domain]  Cd Length: 194  Bit Score: 77.78  E-value: 1.69e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  373 EADLNALDAKVGDGDTGSTFAAGARDIADLLQrrQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQ--- 449
Cdd:TIGR02365  16 KEYLTELDRAIGDGDHGINMARGFSEVKEKLD--AFKDKTIGEILKNTGMTLISKVGGASGPLYGTAFLKASKALKDdei 93

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515  450 --GASVAEALNAGLAQMKFYGGADEGDRTMIDA---LQPALAALLAEPENLQAAFAAAQAGADRT--LHASKagaGRASY 522
Cdd:TIGR02365  94 ldAEDLAEILQAGLEGIQSRGKATPGEKTMVDVwapVVEALRKAADEPDALAAAREAAEQGAEATkdMQATK---GRASY 170

                         170       180
                  ....*....|....*....|....*
gi 490207515  523 LNSDSLrGNMDPGAHAVAMVFKALA 547
Cdd:TIGR02365 171 LGERSI-GHIDPGATSSYYLFQALA 194
DAK1 COG2376
Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is ...
 362-548 4.25e-14

Dihydroxyacetone kinase [Carbohydrate transport and metabolism]; Dihydroxyacetone kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis


Pssm-ID: 441943 [Multi-domain]  Cd Length: 206  Bit Score: 71.38  E-value: 4.25e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 362 VERVTGTLSNLEADLNALDAKVGDGDTGSTFAAGARDIADLLQrrqLPLANLATLFALIGERLTVVMGGSSGVLMSIFFT 441
Cdd:COG2376    1 MKAVADVIAENRKFLNDLDAVVGDGDHGINMARGFDAVRAALD---AAPADPGVVLRAAGMKVASVVGGGSGGLVGTGFL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 442 AAGQKLEQGAS-----VAEALNAGLAQMKFYGGADEGDRTMID-------ALQPALAALLAEPENLQAAFAAAQAGAD-- 507
Cdd:COG2376   78 DAAVALKGETSptadqVAAALRAADEGIQGRGVAYTGDKTNFDaaapaaeAIEEAVAAGTAAAAALDEAAAAAEKGAEat 157

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 490207515 508 RTLHASKagaGRASYLNSDSlRGNMDPGAHAVAMVFKALAQ 548
Cdd:COG2376  158 RSMGAAL---GRATYPGERS-PGHPDPGATSVALLLNGLGA 194
PRK10005 PRK10005
dihydroxyacetone kinase ADP-binding subunit DhaL;
376-548 3.31e-08

dihydroxyacetone kinase ADP-binding subunit DhaL;


Pssm-ID: 182192 [Multi-domain]  Cd Length: 210  Bit Score: 53.97  E-value: 3.31e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 376 LNALDAKVGDGDTGSTFAAGARDIADLLQrrQLPLANLATLFALIGERLTVVMGGSSGVLMSIFFTAAGQKLEQGASVA- 454
Cdd:PRK10005  26 LTGLDREIGDADHGLNMNRGFSKVVEKLP--AIADKDIGFILKNTGMTLLSSVGGASGPLYGTFFIRAAQATQARQSLTl 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490207515 455 ----EALNAGLAQMKFYGGADEGDRTMIDALQPALAALLAEPEN---LQAAFAAAQAGADRTLHAS---KAGAGRASYLN 524
Cdd:PRK10005 104 eelyQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQnlsVPAALNAAVSIAESAAQSTitmQARKGRASYLG 183

                        170       180
                 ....*....|....*....|....
gi 490207515 525 SDSLrGNMDPGAHAVAMVFKALAQ 548
Cdd:PRK10005 184 ERSI-GHQDPGATSVMFMMQALAL 206
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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