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Conserved domains on  [gi|490216563|ref|WP_004114943|]
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ABC transporter permease [Gardnerella vaginalis]

Protein Classification

ABC transporter permease( domain architecture ID 11427312)

ABC transporter permease similar to ABC oligopeptide transporter permease proteins (OppB, AppB, and AmiC), the transmembrane subunits (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporters which generally bind type 2 PBPs

Gene Ontology:  GO:0055085
PubMed:  18535149|17723295
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-315 3.76e-86

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 261.54  E-value: 3.76e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 lveLFPTQGFpTDGWRDFGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLAL 240
Cdd:COG0601  161 ---WLPVSGR-VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNAL 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490216563 241 PQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRL 315
Cdd:COG0601  237 IPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-315 3.76e-86

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 261.54  E-value: 3.76e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 lveLFPTQGFpTDGWRDFGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLAL 240
Cdd:COG0601  161 ---WLPVSGR-VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNAL 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490216563 241 PQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRL 315
Cdd:COG0601  237 IPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-308 1.05e-40

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 144.09  E-value: 1.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:PRK15081  81 MVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 lveLFPTQGfpTDGWRDFgsaflslILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLAL 240
Cdd:PRK15081 161 ---WLPTVG--ADSWQHY-------ILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAM 228

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490216563 241 PQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLH 308
Cdd:PRK15081 229 IPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLY 296
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-101 3.48e-16

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 73.41  E-value: 3.48e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563    1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGD---- 76
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdfga 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 490216563   77 --------FGVSMLTGRSVASTIAMRASITFPL 101
Cdd:pfam19300  81 vghcpapcLGYSFANNEPVWDTIMDRFPTTLSL 113
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 97-307 4.68e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 52.28  E-value: 4.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  97 ITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVaRFCAITAGSVPALWGGMILIMIFGKGIGlvelfptqgfptdgwr 176
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLL-RRIIDLLLSLPSLVLGLLLVLLFGVLLG---------------- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 177 dfGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIM 256
Cdd:cd06261   66 --WGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490216563 257 GVMVIENLFSLPGMGMGLvrdvGLRDLISVQGNLFMLSALFLLVGFAIDVL 307
Cdd:cd06261  144 EFALVSFLGGGEAPGPGT----GLLLIFAILFPGDLGVAAAVALILLLLSL 190
 
Name Accession Description Interval E-value
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 1-315 3.76e-86

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 261.54  E-value: 3.76e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:COG0601    1 MLRYILRRLLQAIPVLLGVSTLVFLLLRLLPGDPAAALLGPRATPEAIAALRAELGLDQPLLVQYLDWLGGLLRGDLGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:COG0601   81 FVYGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 lveLFPTQGFpTDGWRDFGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLAL 240
Cdd:COG0601  161 ---WLPVSGR-VSPWEDFLDALRHLILPALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNAL 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490216563 241 PQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRL 315
Cdd:COG0601  237 IPVVTVLGLQLGGLLGGAVVVETVFSWPGLGRLLVDAILNRDYPVVQGIVLLIAVLVVLVNLLVDLLYALLDPRI 311
PRK15081 PRK15081
glutathione ABC transporter permease GsiC; Provisional
 1-308 1.05e-40

glutathione ABC transporter permease GsiC; Provisional


Pssm-ID: 185039 [Multi-domain]  Cd Length: 306  Bit Score: 144.09  E-value: 1.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:PRK15081   1 MLNYVIKRLLGLIPTLLIVAVLVFLFVHLLPGDPARLAAGPEADAQVVALVRQQLGLDQPLPHQFWHYISNALQGDFGTS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:PRK15081  81 MVSRRPVSEEIASRFMPTLWLTITSMVWAVIFGMAIGIASAVWRNRWPDRLGMTLAVSGISFPAFALGMLLMQVFSVELG 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 lveLFPTQGfpTDGWRDFgsaflslILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLAL 240
Cdd:PRK15081 161 ---WLPTVG--ADSWQHY-------ILPSLTLGAAVAAVMARFTRASFVEVLSEDYMRTARAKGVSETWVVLKHGLRNAM 228

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490216563 241 PQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLH 308
Cdd:PRK15081 229 IPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQAEVLLFSLEFILINLVVDVLY 296
PRK10352 PRK10352
nickel transporter permease NikB; Provisional
 1-315 2.19e-36

nickel transporter permease NikB; Provisional


Pssm-ID: 182400 [Multi-domain]  Cd Length: 314  Bit Score: 132.90  E-value: 2.19e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQV---MAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGDF 77
Cdd:PRK10352   1 MLRYILRRLLLLIPMLLAASVIIFLMLRLGTGDPALDylrLSNLPPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  78 GVSMLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGK 157
Cdd:PRK10352  81 GISFATQRPVLDDLLNFLPATLELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 158 GIGLVelfPTQGFptDGWRdfgsaflSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLR 237
Cdd:PRK10352 161 YLQWL---PAMGY--GGWQ-------HIILPAVSIAFMSLAINARLLRASMLEVAGQRHVTWARLRGLSERQVERRHILR 228

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490216563 238 LALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRL 315
Cdd:PRK10352 229 NASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPVIQCFTLMMVVVFVVCNLIVDLLNAALDPRI 306
PRK10914 PRK10914
dipeptide ABC transporter permease DppB;
1-315 1.20e-35

dipeptide ABC transporter permease DppB;


Pssm-ID: 182834 [Multi-domain]  Cd Length: 339  Bit Score: 131.47  E-value: 1.20e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVE-QLRRDLGLNKPLFVQYLEWIFGVFRGDFGV 79
Cdd:PRK10914   1 MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGISPERHaQLLAELGLDKPMWQQYLHYIWGVMHGDLGI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  80 SMLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMI----- 154
Cdd:PRK10914  81 SLKSRIPVWDEFVPRFKATLELGVCAMIFAVAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLvsvhw 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 155 --------FGKGIGLVELFPTQGF---PTDGW---RDFGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQT 220
Cdd:PRK10914 161 nltpvsgrVSDMVFLDDSNPLTGFmliDTAIWgedGNFIDAVAHMILPAIVLGTIPLAVIVRMTRSSMLEVLGEDYIRTA 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 221 MACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLV 300
Cdd:PRK10914 241 RAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLAGAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILV 320

                        330
                 ....*....|....*
gi 490216563 301 GFAIDVLHRLLDSRL 315
Cdd:PRK10914 321 NLLVDLLYGVVNPRI 335
SapB COG4168
ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];
1-312 2.15e-33

ABC-type antimicrobial peptide export system, permease component SapB [Defense mechanisms];


Pssm-ID: 443329 [Multi-domain]  Cd Length: 321  Bit Score: 124.95  E-value: 2.15e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQvmaglnapdgkveqlrrdlglNKPLFVQYLEWIFGVFRGDFGVS 80
Cdd:COG4168    1 MLIYLLRRLNLLLITLLILSLISFSLLYRDPLNPLS---------------------DASLFSGYLFYLQNLLQGDFGIS 59

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  81 MLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG 160
Cdd:COG4168   60 SINGEPILEQLLTVFPATLELCFLAFLLALLIGIPLGILAGIYRGKWLDKLISSLSLLGFSIPVFWLALLLILFFSLNLG 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 ----------LVELFPTQGFPT-DGWRD--------FGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTM 221
Cdd:COG4168  140 wlpvsgrynlLYEIPPVTGFALiDAWLSdspyrlkaIQSALQHLILPTLVLAVAPTTEVIRLTRQSTEEVMNQNYIKAAA 219

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 222 ACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVG 301
Cdd:COG4168  220 TRGLSRFTIIRRHVLRNALPPIIPQLGLQFSTMLTLAMITEVVFSWPGIGRWLINAIRQQDYAAISAGVIVIGTFVIIVN 299

                        330
                 ....*....|.
gi 490216563 302 FAIDVLHRLLD 312
Cdd:COG4168  300 ILSDILGALLN 310
oppB PRK09471
oligopeptide ABC transporter permease OppB;
1-315 1.46e-22

oligopeptide ABC transporter permease OppB;


Pssm-ID: 181886 [Multi-domain]  Cd Length: 306  Bit Score: 95.52  E-value: 1.46e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   1 MKRMILRRITLFFVALLFISAIVFLALRVLPGD--------VAQVMAGLNApdgkveqlrrDLGLNKPLFVQYLEWIFGV 72
Cdd:PRK09471   1 MLKFILRRCLEAIPTLFILITISFFMMRLAPGSpftgertlPPEVMANIEA----------KYHLNDPIMTQYFSYLKQL 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  73 FRGDFGVSM-LTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMIL 151
Cdd:PRK09471  71 AHGDFGPSFkYKDYSVNDLVASSFPVSAKLGAAAFFLAVILGVSAGVIAALKQNTKWDYTVMGFAMTGVVIPSFVVAPLL 150

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 152 IMIFGKGIGLvelfptqgFPTDGWRdfGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMI 231
Cdd:PRK09471 151 VLIFAITLHW--------LPGGGWN--GGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRRII 220

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 232 WRVGLRLALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLL 311
Cdd:PRK09471 221 LRHALKPALLPVLSYMGPAFVGIITGSMVIETIFGLPGIGQLFVNGALNRDYSLVLSLTILVGALTILFNAIVDVLYAVI 300


                 ....
gi 490216563 312 DSRL 315
Cdd:PRK09471 301 DPKI 304
BPD_transp_1_N pfam19300
Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal ...
 1-101 3.48e-16

Binding-prot-dependent transport system membrane comp, N-term; This is the N-terminal transmembrane domain of the Binding-protein-dependent transport system inner membrane component.


Pssm-ID: 437132 [Multi-domain]  Cd Length: 114  Bit Score: 73.41  E-value: 3.48e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563    1 MKRMILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNAPDGKVEQLRRDLGLNKPLFVQYLEWIFGVFRGD---- 76
Cdd:pfam19300   1 MLRFLVRRTLGAVVILLIISAVTFFLFYAIPRDPARLACGKNCTPETLALIRHNLGLDKPIPVQYWHFLSGIFAGRdfga 80

                          90       100       110
                  ....*....|....*....|....*....|...
gi 490216563   77 --------FGVSMLTGRSVASTIAMRASITFPL 101
Cdd:pfam19300  81 vghcpapcLGYSFANNEPVWDTIMDRFPTTLSL 113
PRK15110 PRK15110
peptide ABC transporter permease SapB;
5-307 1.24e-15

peptide ABC transporter permease SapB;


Pssm-ID: 185065 [Multi-domain]  Cd Length: 321  Bit Score: 76.27  E-value: 1.24e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563   5 ILRRITLFFVALLFISAIVFLALRVLPGDVAQVMAGLNApdgkveqlrrdlglnkplfvqYLEWIFGVFRGDFGVSMLTG 84
Cdd:PRK15110   5 TLRRLLLLIVTLFLLTLVGFSLSYFTPHAPLQGASLWDA---------------------WVFWFNGLLHWDFGVSSING 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  85 RSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIG---- 160
Cdd:PRK15110  64 QPISEQLKEVFPATMELCILAFGFALLVGIPVGIIAGVTRHKWQDNLISALALLGFSIPVFWLALLLTLFFSLTLGwlpv 143

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 161 ------LVELFPTQGFP-TDGW------RD--FGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGM 225
Cdd:PRK15110 144 sgrfdlLYEVKPVTGFAlIDAWlsdspwRDemIMSAIRHMILPVITLAVAPTTEVIRLMRISTIEVYDQNYVKAAATRGL 223

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 226 TKKQMIWRVGLRLALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAID 305
Cdd:PRK15110 224 SRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAIRQQDYAAISAGVMVVGSLVIIVNVLSD 303


                 ..
gi 490216563 306 VL 307
Cdd:PRK15110 304 IL 305
PRK15133 PRK15133
microcin C ABC transporter permease YejB; Provisional
 48-315 9.31e-14

microcin C ABC transporter permease YejB; Provisional


Pssm-ID: 185087 [Multi-domain]  Cd Length: 364  Bit Score: 70.93  E-value: 9.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  48 VEQLRRDLGLNKPLFVQYLEWIFGVFRGDFGVSMLTGRSVASTIAMRASITFPLIFLGLLIALAIGIPLGCLQVLHSGKA 127
Cdd:PRK15133  86 IAEITHRYGFDKPLHERYFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAVRNGSR 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 128 SQVVARFCAITAGSVPALWGGMILIMIFGKGiGLVELFPTQG-----FPTDGWRDFGSAFLSLIlpALTVGIIVGSGFMR 202
Cdd:PRK15133 166 FDVWSSAFIIIGYAIPAFLFAILLIVFFAGG-SYFDLFPLRGlvsanFDSLPWYQKITDYLWHI--TLPVLATVIGGFAA 242

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 203 YTA----ASLEQISNSDIaLQTMACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIM-GVMVIENLFSLPGMGMgLVRD 277
Cdd:PRK15133 243 LTMltknSFLDEIRKQYV-VTARAKGVSEKNILWKHVFRNAMLLVIAGFPATFISMFFtGSLLIEVMFSLNGLGL-LGYE 320

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 490216563 278 VGL-RDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRL 315
Cdd:PRK15133 321 ATVsRDYPVMFGTLYIFTLIGLLLNIVSDISYTLVDPRI 359
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 113-317 1.56e-12

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 65.01  E-value: 1.56e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  113 GIPLGCLQVLHSGKASQVVARFCAITAGSVPALWGGMILIMIFGKGIglvelfptqgfptdgwrdfgsaFLSLILPALTV 192
Cdd:pfam00528   1 GIPLGIIAALRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSI----------------------LGHGILPAIIL 58

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  193 GIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIMGVMVIENLFSLPGMGM 272
Cdd:pfam00528  59 ALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLGSWPGLGL 138

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 490216563  273 GLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSRLSQ 317
Cdd:pfam00528 139 LLIEAILGYDYPEIQGPVLAAALILLLLNLLVDILQRLLDPRVRK 183
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 97-307 4.68e-08

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 52.28  E-value: 4.68e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563  97 ITFPLIFLGLLIALAIGIPLGCLQVLHSGKASQVVaRFCAITAGSVPALWGGMILIMIFGKGIGlvelfptqgfptdgwr 176
Cdd:cd06261    3 NTLLLALIATLLALVLGLLLGIILARKRGKLDRLL-RRIIDLLLSLPSLVLGLLLVLLFGVLLG---------------- 65

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 177 dfGSAFLSLILPALTVGIIVGSGFMRYTAASLEQISNSDIALQTMACGMTKKQMIWRVGLRLALPQLVSVIGLTFAHMIM 256
Cdd:cd06261   66 --WGILPGLGLPALILALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG 143

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|.
gi 490216563 257 GVMVIENLFSLPGMGMGLvrdvGLRDLISVQGNLFMLSALFLLVGFAIDVL 307
Cdd:cd06261  144 EFALVSFLGGGEAPGPGT----GLLLIFAILFPGDLGVAAAVALILLLLSL 190
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 101-314 9.55e-04

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 39.65  E-value: 9.55e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 101 LIFLGLLIALAIGIPLGCLqVLHSGKASQVVARFCAItAGSVPALwgGMILIMIFGKGIGLVelfptqgfptdgwrdfgS 180
Cdd:COG1174   26 LVLLALLIALLIAVPLGIL-ITRRRRLAGLVLGVANI-LQTIPSL--ALLALLIPLLGIGPA-----------------P 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490216563 181 AFLSLILpaLTVGIIVgsgfmRYTAASLEQISNS--DIAlqtMACGMTKKQMIWRVGLRLALPQLVSviGL-TFAHMIMG 257
Cdd:COG1174   85 AIIALVL--YALLPIL-----RNTYTGLRSVDPAvvEAA---RGMGMTPWQRLWRVELPLALPVILA--GIrTAAVQNIG 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490216563 258 VMVIENLFSLPGMGMGLVRDVGLRDLISVQGNLFMLSALFLLVGFAIDVLHRLLDSR 314
Cdd:COG1174  153 TATLAALIGAGGLGDLIFDGLQLNNTALILAGAILVALLALLVDLLLALLERLLTPR 209
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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