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Conserved domains on  [gi|490235941|ref|WP_004134260|]
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MULTISPECIES: GNAT family N-acetyltransferase [Klebsiella]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 11447364)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
SCOP:  3000403

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
2-173 1.43e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.43e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   2 PELVTPHLRCSPLQLDDWPFFLSLQQDPQVMLYVA-DPRPVAEIRDAFDSRLPAWSPGapHWLCLVVRDRYTHAPLGLTG 80
Cdd:COG1670    1 PTLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADG--GALPFAIEDKEDGELIGVVG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  81 YHH--HAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLN 158
Cdd:COG1670   79 LYDidRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVID 158
                        170
                 ....*....|....*
gi 490235941 159 GRWHNDWLFGLLRRD 173
Cdd:COG1670  159 GRYRDHVLYSLLREE 173
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
2-173 1.43e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.43e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   2 PELVTPHLRCSPLQLDDWPFFLSLQQDPQVMLYVA-DPRPVAEIRDAFDSRLPAWSPGapHWLCLVVRDRYTHAPLGLTG 80
Cdd:COG1670    1 PTLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADG--GALPFAIEDKEDGELIGVVG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  81 YHH--HAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLN 158
Cdd:COG1670   79 LYDidRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVID 158
                        170
                 ....*....|....*
gi 490235941 159 GRWHNDWLFGLLRRD 173
Cdd:COG1670  159 GRYRDHVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
9-146 1.93e-26

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 97.42  E-value: 1.93e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941    9 LRcsPLQLDDWPFFLSLQQDPQVM-LYVADPRPVAEIRDAFDSRLPAWSPGAPHWLCLVVRDRythAPLGLTGYH--HHA 85
Cdd:pfam13302   4 LR--PLTEEDAEALFELLSDPEVMrYGVPWPLTLEEAREWLARIWAADEAERGYGWAIELKDT---GFIGSIGLYdiDGE 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490235941   86 PDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFH 146
Cdd:pfam13302  79 PERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
1-163 3.94e-08

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 50.57  E-value: 3.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   1 MPELVTPHLRcsPLQLDDWPFFLSLQQDPQVMLY-VADP-RPVAEIRDAFDSRLPAWSPGAphwlcLVVRDRYTHAPLGL 78
Cdd:PRK15130   1 MPSAHSVKLR--PLEREDLRFVHQLDNNASVMRYwFEEPyEAFVELSDLYDKHIHDQSERR-----FVVECDGEKAGLVE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  79 TGYHHHAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLN 158
Cdd:PRK15130  74 LVEINHVHRRAEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFEVEGELIHEFFIN 153

                 ....*
gi 490235941 159 GRWHN 163
Cdd:PRK15130 154 GEYRN 158
 
Name Accession Description Interval E-value
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
2-173 1.43e-45

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 147.45  E-value: 1.43e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   2 PELVTPHLRCSPLQLDDWPFFLSLQQDPQVMLYVA-DPRPVAEIRDAFDSRLPAWSPGapHWLCLVVRDRYTHAPLGLTG 80
Cdd:COG1670    1 PTLETERLRLRPLRPEDAEALAELLNDPEVARYLPgPPYSLEEARAWLERLLADWADG--GALPFAIEDKEDGELIGVVG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  81 YHH--HAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLN 158
Cdd:COG1670   79 LYDidRANRSAEIGYWLAPAYWGKGYATEALRALLDYAFEELGLHRVEAEVDPDNTASIRVLEKLGFRLEGTLRDALVID 158
                        170
                 ....*....|....*
gi 490235941 159 GRWHNDWLFGLLRRD 173
Cdd:COG1670  159 GRYRDHVLYSLLREE 173
Acetyltransf_3 pfam13302
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
9-146 1.93e-26

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 379112 [Multi-domain]  Cd Length: 139  Bit Score: 97.42  E-value: 1.93e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941    9 LRcsPLQLDDWPFFLSLQQDPQVM-LYVADPRPVAEIRDAFDSRLPAWSPGAPHWLCLVVRDRythAPLGLTGYH--HHA 85
Cdd:pfam13302   4 LR--PLTEEDAEALFELLSDPEVMrYGVPWPLTLEEAREWLARIWAADEAERGYGWAIELKDT---GFIGSIGLYdiDGE 78
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490235941   86 PDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFH 146
Cdd:pfam13302  79 PERAELGYWLGPDYWGKGYATEAVRALLEYAFEELGLPRLVARIDPENTASRRVLEKLGFK 139
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
13-162 3.94e-16

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 71.56  E-value: 3.94e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  13 PLQLDDWPFFLSLQQD---PQVMLYVADPRPVAEIRDAFDSRLpawspgAPHWLCLVVRDRytHAPLGLTGYHHHAP--- 86
Cdd:COG1247    6 PATPEDAPAIAAIYNEaiaEGTATFETEPPSEEEREAWFAAIL------APGRPVLVAEED--GEVVGFASLGPFRPrpa 77
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490235941  87 --DSAEAGFLFAPHAQGKGYGYESLRALCDYAfSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLNGRWH 162
Cdd:COG1247   78 yrGTAEESIYVDPDARGRGIGRALLEALIERA-RARGYRRLVAVVLADNEASIALYEKLGFEEVGTLPEVGFKFGRWL 154
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
76-145 3.52e-08

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 49.44  E-value: 3.52e-08
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   76 LGLTGYHHHAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTgGIRRLTATVTAGNLASKNLLQKVGF 145
Cdd:pfam00583  48 ASLSIIDDEPPVGEIEGLAVAPEYRGKGIGTALLQALLEWARER-GCERIFLEVAADNLAAIALYEKLGF 116
PRK15130 PRK15130
spermidine N1-acetyltransferase; Provisional
1-163 3.94e-08

spermidine N1-acetyltransferase; Provisional


Pssm-ID: 237916  Cd Length: 186  Bit Score: 50.57  E-value: 3.94e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941   1 MPELVTPHLRcsPLQLDDWPFFLSLQQDPQVMLY-VADP-RPVAEIRDAFDSRLPAWSPGAphwlcLVVRDRYTHAPLGL 78
Cdd:PRK15130   1 MPSAHSVKLR--PLEREDLRFVHQLDNNASVMRYwFEEPyEAFVELSDLYDKHIHDQSERR-----FVVECDGEKAGLVE 73
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  79 TGYHHHAPDSAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLN 158
Cdd:PRK15130  74 LVEINHVHRRAEFQIIISPEYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFEVEGELIHEFFIN 153

                 ....*
gi 490235941 159 GRWHN 163
Cdd:PRK15130 154 GEYRN 158
Acetyltransf_4 pfam13420
Acetyltransferase (GNAT) domain;
102-161 2.06e-07

Acetyltransferase (GNAT) domain;


Pssm-ID: 433192 [Multi-domain]  Cd Length: 153  Bit Score: 48.13  E-value: 2.06e-07
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  102 KGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLNGRW 161
Cdd:pfam13420  89 EGINRELINAIIQYARKNQNIENLEACIASNNINAIVFLKAIGFEWLGIERNAIKKNGRW 148
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
78-156 2.17e-07

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 46.57  E-value: 2.17e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  78 LTGYHHHAPDSAEAGFLF-APHAQGKGYGYESLRALCDYAFSTgGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYW 156
Cdd:COG0456    3 ALLGLVDGGDEAEIEDLAvDPEYRGRGIGRALLEAALERARER-GARRLRLEVREDNEAAIALYEKLGFEEVGERPNYYG 81
PRK10151 PRK10151
50S ribosomal protein L7/L12-serine acetyltransferase;
88-168 1.85e-06

50S ribosomal protein L7/L12-serine acetyltransferase;


Pssm-ID: 182270  Cd Length: 179  Bit Score: 45.91  E-value: 1.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  88 SAEAGFLFAPHAQGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLNGRWHNDWLF 167
Cdd:PRK10151  93 TAYIGYWLDESHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPASNQVALRNGFTLEGCLKQAEYLNGAYDDVNLY 172

                 .
gi 490235941 168 G 168
Cdd:PRK10151 173 A 173
PRK10809 PRK10809
30S ribosomal protein S5 alanine N-acetyltransferase;
100-174 7.50e-06

30S ribosomal protein S5 alanine N-acetyltransferase;


Pssm-ID: 182749  Cd Length: 194  Bit Score: 44.34  E-value: 7.50e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490235941 100 QGKGYGYESLRALCDYAFSTGGIRRLTATVTAGNLASKNLLQKVGFHQEGELRECYWLNGRWHNDWLFGLLRRDY 174
Cdd:PRK10809 116 QGQGLMFEALQAAIRYMQRQQHMHRIMANYMPHNKRSGDLLARLGFEKEGYAKDYLLIDGQWRDHVLTALTTPEW 190
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
74-159 1.29e-04

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 40.04  E-value: 1.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490235941  74 APLGLTGYHHHAPDSAEAGFLF-APHAQGKGYGYESLRALCDYAFSTgGIRRLTATVTAGNLASKNLLQKVGFHQEGELr 152
Cdd:COG0454   44 EPIGFAGLRRLDDKVLELKRLYvLPEYRGKGIGKALLEALLEWARER-GCTALELDTLDGNPAAIRFYERLGFKEIERY- 121

                 ....*..
gi 490235941 153 ECYWLNG 159
Cdd:COG0454  122 VAYVGGE 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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