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Conserved domains on  [gi|490282193|ref|WP_004178088|]
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MULTISPECIES: choline BCCT transporter BetT [Enterobacterales]

Protein Classification

BCCT family transporter( domain architecture ID 10003438)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Bacillus subtilis glycine betaine transporter OpuD

CATH:  1.20.5.430
Gene Ontology:  GO:0022857|GO:0071705|GO:0016020
PubMed:  20923416
TCDB:  2.A.15

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-510 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440903  Cd Length: 512  Bit Score: 692.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   1 MSDNDTIPKKStsQINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYG 80
Cdd:COG1292    1 MSDKNKEKFKK--KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  81 DIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVAAAKEAMRLTFFHWGLHAWAIYAIV 159
Cdd:COG1292   79 KIRLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 160 ALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVIL 239
Cdd:COG1292  159 GLALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIII 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 240 IVVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPksSKWL 319
Cdd:COG1292  239 IAVITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWL 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 320 GGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALA 399
Cdd:COG1292  317 GGWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAA 395
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 400 LFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVT 479
Cdd:COG1292  396 LFALLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTAS 475
                        490       500       510
                 ....*....|....*....|....*....|.
gi 490282193 480 IASALPFSVILLISIYGLLKALRRDLTKRES 510
Cdd:COG1292  476 IITALPFSFVLLLMCVSLVKALREDPRRLRS 506
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-510 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 692.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   1 MSDNDTIPKKStsQINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYG 80
Cdd:COG1292    1 MSDKNKEKFKK--KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  81 DIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVAAAKEAMRLTFFHWGLHAWAIYAIV 159
Cdd:COG1292   79 KIRLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 160 ALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVIL 239
Cdd:COG1292  159 GLALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIII 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 240 IVVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPksSKWL 319
Cdd:COG1292  239 IAVITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWL 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 320 GGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALA 399
Cdd:COG1292  317 GGWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAA 395
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 400 LFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVT 479
Cdd:COG1292  396 LFALLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTAS 475
                        490       500       510
                 ....*....|....*....|....*....|.
gi 490282193 480 IASALPFSVILLISIYGLLKALRRDLTKRES 510
Cdd:COG1292  476 IITALPFSFVLLLMCVSLVKALREDPRRLRS 506
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-665 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 682.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   1 MSDNDTIPKKSTsqINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYG 80
Cdd:PRK09928   3 MTDLSHKREKDR--INPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  81 DIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA 160
Cdd:PRK09928  81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 161 LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILI 240
Cdd:PRK09928 161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 241 VVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPkSSKWLG 320
Cdd:PRK09928 241 ALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWMN 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 321 GWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALAL 400
Cdd:PRK09928 320 NWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 401 FNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLaTGGVAN----TPVWQRIFWASLMGIVAIALLLAGGLSALQ 476
Cdd:PRK09928 399 YSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNF-TSKLKDinsdAPNWLRVFWSVAIGLLTLGMLMTNGISALQ 477
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 477 TVTIASALPFSVILLISIYGLLKALRRDLTKRESLSMATI-APTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAM 555
Cdd:PRK09928 478 NTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTApRLVGLQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAM 557
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 556 TLVQEELNKQGTISHIS--DAVEDR----IRLEVDLGNELNFIYEVRLRGYSSPTFALAAmdnneQQTEQHrYYRAEVYL 629
Cdd:PRK09928 558 EEVAQELRLRGAYVELNelPPEEDErlghLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKST-YYRLETFL 631
                        650       660       670
                 ....*....|....*....|....*....|....*.
gi 490282193 630 KEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR 665
Cdd:PRK09928 632 LEGSQGNDLMDYSKEQVINDILDQYERHLNFLHLHR 667
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-504 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 634.19  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   19 VFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   99 FAMLFSAGMGIGLMFFGVAEPVMHYLS-PPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  178 SALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDK 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  258 GIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPkSSKWLGGWTLLYWGWWLSWSPFV 337
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  338 GMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALALFNFLEHFPFSSVLSFIA 417
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELN-GPGDLADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  418 MAMVIVFFVTSADSGAMVVDTLATGGVANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGL 497
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 490282193  498 LKALRRD 504
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-504 8.87e-164

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 477.62  E-value: 8.87e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   57 SWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGT-PETVA 135
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAgPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  136 AAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYG 215
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  216 VLQVNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTG 295
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  296 GYLSELVSKTFNLYAYEPKSSkWLGGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNS 375
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  376 AIYLIMNQGATDLANTVQQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVAN---TPVWQR 452
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLgeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490282193  453 IFWASLMGIVAIALLLA-GGLSALQTVTIASALPFSVILLISIYGLLKALRRD 504
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-510 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 692.66  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   1 MSDNDTIPKKStsQINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYG 80
Cdd:COG1292    1 MSDKNKEKFKK--KIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKYG 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  81 DIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVAAAKEAMRLTFFHWGLHAWAIYAIV 159
Cdd:COG1292   79 KIRLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYALV 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 160 ALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVIL 239
Cdd:COG1292  159 GLALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQIII 238
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 240 IVVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPksSKWL 319
Cdd:COG1292  239 IAVITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGWL 316
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 320 GGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALA 399
Cdd:COG1292  317 GGWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEAA 395
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 400 LFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVT 479
Cdd:COG1292  396 LFALLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTAS 475
                        490       500       510
                 ....*....|....*....|....*....|.
gi 490282193 480 IASALPFSVILLISIYGLLKALRRDLTKRES 510
Cdd:COG1292  476 IITALPFSFVLLLMCVSLVKALREDPRRLRS 506
PRK09928 PRK09928
choline transport protein BetT; Provisional
1-665 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 682.96  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   1 MSDNDTIPKKSTsqINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYG 80
Cdd:PRK09928   3 MTDLSHKREKDR--INPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  81 DIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA 160
Cdd:PRK09928  81 SIKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMG 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 161 LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILI 240
Cdd:PRK09928 161 MALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALI 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 241 VVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPkSSKWLG 320
Cdd:PRK09928 241 ALSVIIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWMN 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 321 GWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALAL 400
Cdd:PRK09928 320 NWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGF 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 401 FNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLaTGGVAN----TPVWQRIFWASLMGIVAIALLLAGGLSALQ 476
Cdd:PRK09928 399 YSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNF-TSKLKDinsdAPNWLRVFWSVAIGLLTLGMLMTNGISALQ 477
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 477 TVTIASALPFSVILLISIYGLLKALRRDLTKRESLSMATI-APTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAM 555
Cdd:PRK09928 478 NTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTApRLVGLQDRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAM 557
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 556 TLVQEELNKQGTISHIS--DAVEDR----IRLEVDLGNELNFIYEVRLRGYSSPTFALAAmdnneQQTEQHrYYRAEVYL 629
Cdd:PRK09928 558 EEVAQELRLRGAYVELNelPPEEDErlghLDLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKST-YYRLETFL 631
                        650       660       670
                 ....*....|....*....|....*....|....*.
gi 490282193 630 KEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR 665
Cdd:PRK09928 632 LEGSQGNDLMDYSKEQVINDILDQYERHLNFLHLHR 667
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
19-504 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 634.19  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   19 VFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSW 98
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   99 FAMLFSAGMGIGLMFFGVAEPVMHYLS-PPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLR 177
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLSpPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  178 SALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDK 257
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  258 GIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPkSSKWLGGWTLLYWGWWLSWSPFV 337
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  338 GMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATDLANTVQQDVALALFNFLEHFPFSSVLSFIA 417
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELN-GPGDLADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  418 MAMVIVFFVTSADSGAMVVDTLATGGVANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGL 497
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 490282193  498 LKALRRD 504
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
57-504 8.87e-164

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 477.62  E-value: 8.87e-164
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   57 SWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVGT-PETVA 135
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAgPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  136 AAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYG 215
Cdd:TIGR00842  81 AQEQALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  216 VLQVNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTG 295
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  296 GYLSELVSKTFNLYAYEPKSSkWLGGWTLLYWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNS 375
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  376 AIYLIMNQGATDLANTVQQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVAN---TPVWQR 452
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGGQLgeePPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490282193  453 IFWASLMGIVAIALLLA-GGLSALQTVTIASALPFSVILLISIYGLLKALRRD 504
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK09950 PRK09950
putative transporter; Provisional
14-504 6.59e-61

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 211.96  E-value: 6.59e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  14 QINKAVFFTSALLIFLLVAFAAVFPD----VADKNFKLLQQQIFTNASWFYILAVALILlsvtFLGLSRYGDIKLGpdHA 89
Cdd:PRK09950   7 KKDKPLISTSLLAVFFIVAALSLFPQqsaaAANTIFQWVTRTFGSPVQLFVLLAMILVL----YLATSKYGNIRLG--EG 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  90 QPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVAAAKEAMRLTFFHWGLHAWAIYAIVALILAF-FS 167
Cdd:PRK09950  81 KPEYSTLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGLNiAPRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFH 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 168 YRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILIVVITGLA 247
Cdd:PRK09950 161 VRKNKGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIF 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 248 TISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSktFNLYAYEPKSSKWLGGWTLLYW 327
Cdd:PRK09950 241 CLSSYIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQ--MSLFTDPMGDGSFTRNWTVFYW 318
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 328 GWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNqGATD---LANTVQQDVALAlfNFL 404
Cdd:PRK09950 319 LWWISYTPGVAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFIN-GVINvpqILNTLGGETAVQ--QLL 395
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 405 EHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLATGGVAN----TPVwQRIFWASLMGIVAIALLLAGGLS-ALQTVT 479
Cdd:PRK09950 396 SSLPAGKLFLAAYLGIMIIFLASHMDAVAYTMAATSTRNLREgddpDRG-LRLFWCVVITLIPLSILFTGASLdTMKTTV 474
                        490       500
                 ....*....|....*....|....*
gi 490282193 480 IASALPFSVILLISIYGLLKALRRD 504
Cdd:PRK09950 475 VLTALPFLVILLIKVYGFIRWLKQD 499
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
9-502 4.36e-59

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 206.89  E-value: 4.36e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193   9 KKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKNFKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDh 88
Cdd:PRK03356   4 EKKKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDE- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193  89 aQPDFSYHSWFAMLFSAGMGIGLMFFGVAEPVMHYLSPPVG-TPETVAAAKEAMRLTFFHWGLHAWAIYAIVALILAFFS 167
Cdd:PRK03356  83 -KPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFF 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 168 YRHGLPLTLRS-ALYPIIGDR-IYGPVGHAVDIFAVIGTVFGVATSLGYGVLQVNAGLNHLFGVPINETVQVILIVVITG 245
Cdd:PRK03356 162 FVRKMDVIRPSsTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWII 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 246 LATISVVSGLDKGIRILSELNLGLALLLLALVLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYepKSSKWLGGWTLL 325
Cdd:PRK03356 242 LNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPI--GKGGFPQGWTVF 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 326 YWGWWLSWSPFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLiMNQGATDLANTVQQD-VALALFNFL 404
Cdd:PRK03356 320 YWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLL-MDKNIINIPNLIEQYgVARAIIETW 398
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490282193 405 EHFPFSSVLSFIAMAMVIVFFVTSADSG----AMVVDTLATGGvANTPVWQRIFWASLMGIVAIALLLAGGLSALQTVTI 480
Cdd:PRK03356 399 AALPLSTATMWGFFILCFIATVTLINACsytlAMSTCREVRDG-EEPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAII 477
                        490       500
                 ....*....|....*....|..
gi 490282193 481 ASALPFSVILLISIYGLLKALR 502
Cdd:PRK03356 478 AGGCPLFFVNIMVTLSFIKDAK 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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