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Conserved domains on  [gi|490286351|ref|WP_004182126|]
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MULTISPECIES: iron-dicitrate ABC transporter permease FecC [Enterobacterales]

Protein Classification

iron-dicitrate ABC transporter permease FecC( domain architecture ID 10793551)

iron-dicitrate ABC transporter permease FecC is part of the binding-protein-dependent transport system for citrate-dependent Fe(3+), and may be responsible for the translocation of the substrate across the membrane

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
10-332 1.49e-156

iron-dicitrate ABC transporter permease FecC;


:

Pssm-ID: 183042  Cd Length: 323  Bit Score: 441.06  E-value: 1.49e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  10 LWGLPVAVLIIIFWLSLFCYSAIPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPM 89
Cdd:PRK11228   1 LWGLPVAALIGLFWLSLFCYSAIPISAADALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  90 ASPSLLGINSGAALAMALTSALSPTPVAGYSLSFIAACGGGVSWLLVMTAGGGFRHTQDRNKLILAGIALSAFCMALTRI 169
Cdd:PRK11228  81 ASPSLLGINSGAALAMALTSALSPTPFAGYSLAFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 170 TLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLL 249
Cdd:PRK11228 161 TLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 250 VGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVR 329
Cdd:PRK11228 241 VGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLAR 320


                 ...
gi 490286351 330 RRG 332
Cdd:PRK11228 321 RRG 323
 
Name Accession Description Interval E-value
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
10-332 1.49e-156

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 441.06  E-value: 1.49e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  10 LWGLPVAVLIIIFWLSLFCYSAIPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPM 89
Cdd:PRK11228   1 LWGLPVAALIGLFWLSLFCYSAIPISAADALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  90 ASPSLLGINSGAALAMALTSALSPTPVAGYSLSFIAACGGGVSWLLVMTAGGGFRHTQDRNKLILAGIALSAFCMALTRI 169
Cdd:PRK11228  81 ASPSLLGINSGAALAMALTSALSPTPFAGYSLAFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 170 TLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLL 249
Cdd:PRK11228 161 TLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 250 VGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVR 329
Cdd:PRK11228 241 VGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLAR 320


                 ...
gi 490286351 330 RRG 332
Cdd:PRK11228 321 RRG 323
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 31-332 3.12e-78

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 241.13  E-value: 3.12e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  31 AIPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSA 110
Cdd:COG0609    6 AVPISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLAIV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 111 LSPTpVAGYSLSFIAACGGGVSWLLVMTAGGGFRHTqDRNKLILAGIALSAFCMALTRITLLLA-EDHAYGIFYWLAGGV 189
Cdd:COG0609   86 LGGG-LSALGLPLAAFLGALLAALLVYLLARRGGGL-SPLRLVLAGVAVSALFSALTSLLLLLAdPEQLRSIVFWLMGSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 190 SHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPH 269
Cdd:COG0609  164 AGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPH 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490286351 270 LARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG 332
Cdd:COG0609  244 IARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 18-330 1.74e-65

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 208.92  E-value: 1.74e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   18 LIIIFWLSLFcYSAIPVSGADAIRALLPGHTPTLpEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGI 97
Cdd:pfam01032   2 LLLLILLSLF-IGAVKISPSDVFSALLGGDDSLA-ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   98 NSGAALAMALTSALSPTPvAGYSLSFIAACGGGVSWLLVMTAGGGFRHTqDRNKLILAGIALSAFCMALTR-ITLLLAED 176
Cdd:pfam01032  80 SSGAALGAVLAILLGGSL-SLFALPLAAFIGALLAALLVYFLSRGRGGA-SPLRLILAGIAVSALLSALTSlLLLLLNPE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  177 HAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSV 256
Cdd:pfam01032 158 ALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAV 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490286351  257 AGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRR 330
Cdd:pfam01032 238 VGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 65-328 2.55e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 157.72  E-value: 2.55e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  65 LVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTpVAGYSLSFIAACGGGVSWLLVMTAGGGFR 144
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIG-LSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 145 HTQdrNKLILAGIALSAFCMALTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVS 224
Cdd:cd06550   81 LSP--SKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 225 DSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARAL 304
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                        250       260
                 ....*....|....*....|....
gi 490286351 305 aFPGDLPAGAVLALIGSPCFVWLV 328
Cdd:cd06550  239 -LPSELPVGPVTALLGAPYFLYLL 261
 
Name Accession Description Interval E-value
fecC PRK11228
iron-dicitrate ABC transporter permease FecC;
10-332 1.49e-156

iron-dicitrate ABC transporter permease FecC;


Pssm-ID: 183042  Cd Length: 323  Bit Score: 441.06  E-value: 1.49e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  10 LWGLPVAVLIIIFWLSLFCYSAIPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPM 89
Cdd:PRK11228   1 LWGLPVAALIGLFWLSLFCYSAIPISAADALNALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGALLQTLTHNPL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  90 ASPSLLGINSGAALAMALTSALSPTPVAGYSLSFIAACGGGVSWLLVMTAGGGFRHTQDRNKLILAGIALSAFCMALTRI 169
Cdd:PRK11228  81 ASPSLLGINSGAALAMALTSALSPTPFAGYSLAFIAACGGGLSWLLVMTAGGGWRHTHDRNRLILAGIALSALCMALTRI 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 170 TLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLL 249
Cdd:PRK11228 161 TLLLAEDHAYGIFYWLAGGVSHARWQEVWQLLPFVVTAVPVVLLLANQLNLLNLSDSSAHTLGVNLTRLRLVVNMLVLLL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 250 VGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVR 329
Cdd:PRK11228 241 VGACVSVAGPVAFIGLLVPHLARFWIGYDQRNVLPMSMLLGATLMLLADLLARALAFPGELPAGAVLALIGAPCFVWLAR 320


                 ...
gi 490286351 330 RRG 332
Cdd:PRK11228 321 RRG 323
FepD COG0609
ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and ...
 31-332 3.12e-78

ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440374  Cd Length: 306  Bit Score: 241.13  E-value: 3.12e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  31 AIPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSA 110
Cdd:COG0609    6 AVPISLSDVLRALLGPDGDPTADLIVWDLRLPRVLLALLVGAALAVAGALMQGLTRNPLADPGILGVSSGAALGAVLAIV 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 111 LSPTpVAGYSLSFIAACGGGVSWLLVMTAGGGFRHTqDRNKLILAGIALSAFCMALTRITLLLA-EDHAYGIFYWLAGGV 189
Cdd:COG0609   86 LGGG-LSALGLPLAAFLGALLAALLVYLLARRGGGL-SPLRLVLAGVAVSALFSALTSLLLLLAdPEQLRSIVFWLMGSL 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 190 SHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPH 269
Cdd:COG0609  164 AGASWDDVLLLLPVLLIGLLLALLLARALNALALGDETARSLGVNVERLRLLLLLLAALLTGAAVAVAGPIGFVGLVVPH 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490286351 270 LARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG 332
Cdd:COG0609  244 IARLLVGPDHRRLLPASALLGALLLLLADTLARTILAPAELPVGIVTALIGAPFFLYLLRRRR 306
FecCD pfam01032
FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport ...
 18-330 1.74e-65

FecCD transport family; This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.


Pssm-ID: 426003  Cd Length: 311  Bit Score: 208.92  E-value: 1.74e-65
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   18 LIIIFWLSLFcYSAIPVSGADAIRALLPGHTPTLpEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGI 97
Cdd:pfam01032   2 LLLLILLSLF-IGAVKISPSDVFSALLGGDDSLA-ALIVLDLRLPRVLAALLVGAALAVSGALLQTVTRNPLADPSILGI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   98 NSGAALAMALTSALSPTPvAGYSLSFIAACGGGVSWLLVMTAGGGFRHTqDRNKLILAGIALSAFCMALTR-ITLLLAED 176
Cdd:pfam01032  80 SSGAALGAVLAILLGGSL-SLFALPLAAFIGALLAALLVYFLSRGRGGA-SPLRLILAGIAVSALLSALTSlLLLLLNPE 157

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  177 HAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSV 256
Cdd:pfam01032 158 ALQSILFWLMGSLSGANWSDVLILLPLLLIGLILLLLLARKLNLLSLGDDTAKSLGVNVNRVRLLLLLLASLLTAASVAV 237

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490286351  257 AGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRR 330
Cdd:pfam01032 238 VGPIGFVGLIVPHIARLLVGANHRRLLPLSALLGALLLLLADILARTILSPYELPVGIVTALIGAPFFIYLLLR 311
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
5-332 3.24e-52

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 182.35  E-value: 3.24e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   5 KHPVLLWGLPVAVLIIIFWLSLFcysaiPVSGADAIRALLPGHTPtlpeaLVQNLRLPRSLVAVLIGASLALAGTLLQTL 84
Cdd:PRK10577 352 RRVLAWLLALGLLLLLALVVALS-----FGRDAHGWNWLSGQLLD-----ALLPLRLPRLLAALLAGAMLAVAGTLLQRL 421

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  85 THNPMASPSLLGINSGAALAMALTSALSPTPVAGySLSFIAACGGGVSWLLVMTAGGgfRHTQDRNKLILAGIALSAFCM 164
Cdd:PRK10577 422 TRNPLASPEVLGISSGAGLGVVLALFLVPGAGFG-WLLAAALLGALAALALILLLAR--RGGFAPERLLLTGIALSALFT 498

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 165 ALTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINM 244
Cdd:PRK10577 499 ALIQLLLASGDPRAAQLLTWLSGSTYGVTWAQALPLLIVAVLLLALALLLRRWLDLLPLGDDTARALGLPVTRARLALLL 578

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 245 LVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCF 324
Cdd:PRK10577 579 LAALLTAAATATVGPLSFVGLMAPHLARMLGGRRARPQLVLAALLGALLMVLADWLGRTLLFPYQIPAGLLAALIGAPYF 658


                 ....*...
gi 490286351 325 VWLVRRRG 332
Cdd:PRK10577 659 LWLLRRSR 666
FepG COG4779
ABC-type enterobactin transport system, permease component [Inorganic ion transport and ...
 8-331 7.79e-50

ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 443810  Cd Length: 344  Bit Score: 169.15  E-value: 7.79e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   8 VLLWGLPVAVLIIIFWLSLFCYSAIPVSGADAIRALLpGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHN 87
Cdd:COG4779   22 ALLVTLVLLLLLLALAVLALTLGDYPLSPGDVLRALL-GEGDPGASFVVLELRLPRALAALLVGAALGLSGAIFQSLTRN 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  88 PMASPSLLGINSGAALAMALTSALSPTpvAGYSLSFIAACGGGVSWLLVMtaGGGFRHTQDRNKLILAGIALSAFCMALT 167
Cdd:COG4779  101 PLASPDIIGITAGASAGAVAAIVVLGG--SGLAVALGALAGGLATALLVY--LLAWRGGVSGYRLILVGIGVSAMLTAVN 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 168 RITLLLAE-DHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLV 246
Cdd:COG4779  177 SYLLTRADlEDAQSAAVWLTGSLNGRTWEDVLPLAVALAVLLPLALALARRLRLLELGDDTAAALGVRVERTRLLLLLVA 256

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 247 LLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPvSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVW 326
Cdd:COG4779  257 VALAAVATAAAGPIAFVALAAPQIARRLTRSPGPPLLP-SALVGALLLLAADLVAQHLLAPVQLPVGVVTGALGGPYLLW 335


                 ....*
gi 490286351 327 LVRRR 331
Cdd:COG4779  336 LLIRE 340
PRK10577 PRK10577
Fe(3+)-hydroxamate ABC transporter permease FhuB;
6-330 1.36e-46

Fe(3+)-hydroxamate ABC transporter permease FhuB;


Pssm-ID: 236720 [Multi-domain]  Cd Length: 668  Bit Score: 166.94  E-value: 1.36e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   6 HPVLLWGLPVAVLIIIFWLSLFCYSAiPVSGADAIRALLPGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLT 85
Cdd:PRK10577   9 RARLPALLLALLLLLALALTLTQLSA-ALPLSQWLQALWGPDADDLEQLLLHYSRLPRLAIALLVGAALGLAGALLQQVL 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  86 HNPMASPSLLGINSGAALAMALTSALSPTPVAGYSLsFIAACGGGVSWLLVMTAGGGFRHTQDRnkLILAGIALSAFCMA 165
Cdd:PRK10577  88 RNPLASPTTLGVAAGAQLALVLATLFAPALLALASQ-LAAFAGGLLAAALVFALAGGKRLSPLR--LVLAGMVVSLYLGA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 166 LTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINML 245
Cdd:PRK10577 165 LTTLLLLFNEQYLQGLFLWGAGSLAQNDWSGVQRLLPRLLVGLLLLLLLARPLTLLGLGDDVARSLGLAVSLTRLAALAL 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 246 VLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPG--DLPAGAVLALIGSPC 323
Cdd:PRK10577 245 AVLLSAAVVSAVGPIGFIGLAAPNLARLLGARRLRARLPLSPLIGALLLLLTDQLVRLLAGVGgeLLPTGAVTALIGAPL 324


                 ....*..
gi 490286351 324 FVWLVRR 330
Cdd:PRK10577 325 LLWLLPR 331
BtuC COG4139
ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and ...
 55-332 2.00e-46

ABC-type cobalamin transport system, permease component BtuC [Coenzyme transport and metabolism];


Pssm-ID: 443314  Cd Length: 327  Bit Score: 160.02  E-value: 2.00e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  55 LVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPVAGYSLSFIAACGGGVSWL 134
Cdd:COG4139   50 FVWQLRLPRTLAAVLVGASLAVSGAVMQALFENPLAEPGLLGISNGAGVGLVLVVLLGGGLLPPWLLSLAAIAGALLVTL 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 135 LVMTAGggfRHTQDRNKLILAGIALSAFCMALTRITLLLAEDHAY-GIFYWLAGGVSHAHWQDVWqLLPVVVTAVPVVLL 213
Cdd:COG4139  130 LLLAFA---RRRLSNARLLLIGVALGIICSAIMTWAVYFSSSLDLrQLMYWMMGSFGGVDWRQLW-LLLALLPVLLWLCL 205

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 214 LANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATL 293
Cdd:COG4139  206 QGKPLNLLLLGENQARQLGLSVHRWRNLLVLATGLLVGVSVALAGPIGFVGLVVPHLLRLLGTTDHRFLLPACALAGAAL 285

                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 490286351 294 MLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG 332
Cdd:COG4139  286 LLLADIIARLALSSAELPIGVVTATLGAPVFIWLLLRRR 324
TM_ABC_iron-siderophores_like cd06550
Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 65-328 2.55e-46

Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The TMs are bundles of alpha helices that transverse the cytoplasmic membrane multiple times. The two ABCs bind and hydrolyze ATP and drive the transport reaction. Each TM has a prominent cytoplasmic loop which contacts an ABC and represents a conserved motif. The two TMs form either a homodimer (e.g. in the case of the BtuC subunits of the Escherichia coli BtuCD vitamin B12 transporter), a heterodimer (e.g. the TroC and TroD subunits of the Treponema pallidum general transition metal transporter, TroBCD), or a pseudo-heterodimer (e.g. the FhuB protein of the E. coli ferrichrome transporter, FhuBC). FhuB contains two tandem TMs which associate to form the pseudo-heterodimer. Both FhuB TMs are found in this hierarchy.


Pssm-ID: 119348 [Multi-domain]  Cd Length: 261  Bit Score: 157.72  E-value: 2.55e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  65 LVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTpVAGYSLSFIAACGGGVSWLLVMTAGGGFR 144
Cdd:cd06550    2 LAALLVGAALAVSGAILQSLTRNRLASPSILGISHGALLGVVLALLLGIG-LSNYALGAFAFAGALAIALLVLLLASRGG 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 145 HTQdrNKLILAGIALSAFCMALTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVS 224
Cdd:cd06550   81 LSP--SKLILIGIVLSAFFSAGVILISLLSDDSLQDLNIWLFGSILGVTWEDLLILLIILLLVLLLLLLLSRKLNLLTFD 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 225 DSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARAL 304
Cdd:cd06550  159 EDLAKSLGINVNLLRLLLLLLVALLVVAAVALVGVILFVGLIAPHLARRLFGRSHRYLLPLSALLGAILLLLGDLLSRTL 238

                        250       260
                 ....*....|....*....|....
gi 490286351 305 aFPGDLPAGAVLALIGSPCFVWLV 328
Cdd:cd06550  239 -LPSELPVGPVTALLGAPYFLYLL 261
PRK03784 PRK03784
vtamin B12-transporter permease; Provisional
 55-331 3.45e-40

vtamin B12-transporter permease; Provisional


Pssm-ID: 235159  Cd Length: 331  Bit Score: 143.56  E-value: 3.45e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  55 LVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPVAGYSLSFIAACGGGVSWL 134
Cdd:PRK03784  53 FVWQLRLPRTLAVLLVGAALAVSGAVMQALFENPLAEPGLLGVSNGAGVALVAAVLLGQGLLPPWALSLCAIAGALLITL 132

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 135 LVMtaGGGFRHTQDRNKLILAGIALSAFCMALTRITLLLAEDHAY-GIFYWLAGGVSHAHWQDVWqLLPVVVTAVPVVLL 213
Cdd:PRK03784 133 ILL--RFARRHRLSTSRLLLAGVALGIICSALMTWAVYFSTSLDLrQLMYWMMGGFGGVDWRQSW-LMLALLPVLIWLCC 209

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 214 LANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATL 293
Cdd:PRK03784 210 QGRPLNMLALGEISARQLGLPLWFWRNLLVLATGWLVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLLPGCALAGASL 289

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 490286351 294 MLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRR 331
Cdd:PRK03784 290 LLLADIVARLALASAELPIGVVTATLGAPVFIWLLLRS 327
fecD PRK09777
Fe(3+) dicitrate ABC transporter permease subunit FecD;
15-330 2.54e-39

Fe(3+) dicitrate ABC transporter permease subunit FecD;


Pssm-ID: 182071  Cd Length: 318  Bit Score: 140.95  E-value: 2.54e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  15 VAVLIIIFWLSLFcYSAIPVSGADAIRALLPGHTPTLpeaLVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSL 94
Cdd:PRK09777  10 TLALAGCALLSLR-MGVIPLPWRALLTDWQAGDEHYY---VLMEYRLPRLLLALFVGAALAVSGVLVQGIVRNPLASPDI 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  95 LGINSGAALAMALTSALSPTpVAGYSLSFIAACGGGVSWLLVMTAGGgfrhTQDRNKLILAGIALSAFCMALTRITLLLA 174
Cdd:PRK09777  86 LGVNHAASLASVGALLLFPS-LPVMWLPLLAFIGGMAGLILLKMLAG----THQPMKLALTGVALSALWASLTDYLMLSR 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 175 EDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACV 254
Cdd:PRK09777 161 PQDINNALLWLTGSLWGRDWSFVKVALPWLILLLPLSLSFCRDLDLLALGDARATTLGVSVPHTQFWALLLAVALTATGV 240

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490286351 255 SVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLALIGSPCFVWLVRR 330
Cdd:PRK09777 241 AACGPISFIGLVVPHLMRSLVGGRHRRLLPVSALTGALLLLLADLLARIIHPPLELPAGVLTAIIGAPWFFWLLVR 316
PRK10441 PRK10441
Fe(3+)-siderophore ABC transporter permease;
55-332 4.03e-36

Fe(3+)-siderophore ABC transporter permease;


Pssm-ID: 182464  Cd Length: 335  Bit Score: 132.91  E-value: 4.03e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  55 LVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAALAMALTSALSPTPVAGYSLSFiAACGGGVSWL 134
Cdd:PRK10441  55 IVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGASFAIVLGAALFGYSSAQEQLAM-AFAGALVASL 133

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 135 LVMTAGGGFRHTQDRNKLILAGIALSAFCMALTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLL 214
Cdd:PRK10441 134 IVAFTGSQGGGQLSPVRLTLAGVALAAVLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLL 213

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 215 ANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSMLLGATLM 294
Cdd:PRK10441 214 SRALNSLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGADHRWSLPVTLLATPALL 293

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 490286351 295 LMADVLARALAfPGDLPAGAVLALIGSPCFVWLVRRRG 332
Cdd:PRK10441 294 LFADIIGRLLV-PGELRVSVVSAFIGAPVLIFLVRRKT 330
btuC PRK09535
cobalamin ABC transporter permease BtuC;
49-331 2.42e-35

cobalamin ABC transporter permease BtuC;


Pssm-ID: 236553  Cd Length: 366  Bit Score: 131.80  E-value: 2.42e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  49 PTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAAL-AMALTSALSPTPVAGYSLSFIAAC 127
Cdd:PRK09535  84 PETAQTIVLQIRLPRILLAATVGFALAAAGTVMQGFFRNPMADPSIIGVSSGAAVgAVAAIVLPLAVPFGLQAAAFAGAL 163

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 128 GGGVSWLLVMTAGGgfrHTQDRNkLILAGIALSAFCMALTRITLLLAEDHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTA 207
Cdd:PRK09535 164 VAAFGVYAIATENG---RTPVAT-LLLAGVAVQTFLGAVISYLLLHSGESLRRAVYWLMGHLHGSTWSDVEVALPVVVVG 239

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 208 VPVVLLLANQLNLLNVSDSTAHTLGVNLPRLRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGFDQRNVLPVSM 287
Cdd:PRK09535 240 FVVLLAYARDLNVLLLGEEDAHTLGIEVERTKRLLLALASVVTAAAVAVAGVIGFVGLIVPHVMRLLVGPDHRILLPTSA 319

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 490286351 288 LLGATLMLMADVLARalAFPGDLPAGAVLALIGSPCFVWLVRRR 331
Cdd:PRK09535 320 LAGASFLVATDTVAR--SGPAEVPVGIVTAALGAPFFLYLLRTR 361
PRK10440 PRK10440
iron-enterobactin ABC transporter permease;
1-330 8.13e-27

iron-enterobactin ABC transporter permease;


Pssm-ID: 182463  Cd Length: 330  Bit Score: 107.87  E-value: 8.13e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351   1 MTALKHPVLLWGLPVAVLIIIFWLSLfCYSAIPVSGADAIRALLpGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTL 80
Cdd:PRK10440   2 IYVSRRLLITCLLLLAACVAAGLWGL-RSGAVTLETSQVFAALM-GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAI 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351  81 LQTLTHNPMASPSLLGINSGAalamaLTSALSPTPVAGYSLSFIA--ACGGGVSWLLVMTAGGgFRHTQDRNKLILAGIA 158
Cdd:PRK10440  80 FQSLMRNPLGSPDVMGFNTGA-----WSGVLVAMVLFGQDLTAIAlaAMAGGIVTSLLVWLLA-WRNGIDTFRLIIIGIG 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 159 LSAFCMALTRITLLLAE-DHAYGIFYWLAGGVSHAHWQDVWQLLPVVVTAVPVVLLLANQLNLLNVSDSTAHTLGVNLPR 237
Cdd:PRK10440 154 VRAMLVAFNTWLLLKASlETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLEMGDDTACALGVSVER 233

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490286351 238 LRLIINMLVLLLVGACVSVAGPVAFISLLVPHLARFWAGfDQRNVLPVSMLLGATLMLMADVLARALAFPGDLPAGAVLA 317
Cdd:PRK10440 234 SRLLLMLVAVVLTAAATALAGPISFIALVAPHIARRLSG-TARWGLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTV 312

                        330
                 ....*....|...
gi 490286351 318 LIGSPCFVWLVRR 330
Cdd:PRK10440 313 SLGGIYLIVLLIQ 325
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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