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Conserved domains on  [gi|490307151|ref|WP_004202221|]
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MULTISPECIES: sulfurtransferase complex subunit TusB [Klebsiella]

Protein Classification

sulfurtransferase complex subunit TusB( domain architecture ID 10014265)

sulfurtransferase complex subunit TusB is part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK13510 PRK13510
sulfurtransferase complex subunit TusB;
1-95 8.67e-53

sulfurtransferase complex subunit TusB;


:

Pssm-ID: 184101  Cd Length: 95  Bit Score: 159.76  E-value: 8.67e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151  1 MLHTLSVSPWHADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYT 80
Cdd:PRK13510  1 MLHTLSRSPWLTDFAALLRLLKEGDDLLLLQDGVTAALKGNRFLESLRNAPIKLYALKEDLIARGLTGQISDSIILISYT 80

                        90
                ....*....|....*
gi 490307151 81 DFVRLTVKHAGQLAW 95
Cdd:PRK13510 81 DFVRLTVKHSQQMAW 95
 
Name Accession Description Interval E-value
PRK13510 PRK13510
sulfurtransferase complex subunit TusB;
1-95 8.67e-53

sulfurtransferase complex subunit TusB;


Pssm-ID: 184101  Cd Length: 95  Bit Score: 159.76  E-value: 8.67e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151  1 MLHTLSVSPWHADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYT 80
Cdd:PRK13510  1 MLHTLSRSPWLTDFAALLRLLKEGDDLLLLQDGVTAALKGNRFLESLRNAPIKLYALKEDLIARGLTGQISDSIILISYT 80

                        90
                ....*....|....*
gi 490307151 81 DFVRLTVKHAGQLAW 95
Cdd:PRK13510 81 DFVRLTVKHSQQMAW 95
TusB COG2168
Sulfur transfer complex TusBCD TusB component, DsrH family [Translation, ribosomal structure ...
 1-95 6.94e-41

Sulfur transfer complex TusBCD TusB component, DsrH family [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441771  Cd Length: 96  Bit Score: 129.57  E-value: 6.94e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151  1 MLHTLSVSPWH-ADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSY 79
Cdd:COG2168   1 MLHTVSKSPFEtNDLDSCLRLLTPGDALLLIQDGVYAALKGSRALALLLAAPIKVYALKEDLEARGLTAQISDGVKLIDY 80

                        90
                ....*....|....*.
gi 490307151 80 TDFVRLTVKHAGQLAW 95
Cdd:COG2168  81 AGFVELTEKHDKQISW 96
DsrH pfam04077
DsrH like protein; DsrH is involved in oxidation of intracellular sulphur in the phototrophic ...
 8-92 1.47e-32

DsrH like protein; DsrH is involved in oxidation of intracellular sulphur in the phototrophic sulphur bacterium Chromatium vinosum D.


Pssm-ID: 461159  Cd Length: 87  Bit Score: 108.42  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151   8 SPWH-ADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYTDFVRLT 86
Cdd:pfam04077  2 SPFEtNALDSCLRLLTPGDAVLLIQDGVYAALKGNRFLAALQAAGVKLYALKEDLEARGLSDQISPGVKVIDYDGFVDLT 81


                 ....*.
gi 490307151  87 VKHAGQ 92
Cdd:pfam04077 82 VKHDKV 87
sulf_tusB_dsrH TIGR03011
sulfur relay protein TusB/DsrH; The three proteins TusB, TusC, and TusD form a heterohexamer ...
 3-95 1.76e-32

sulfur relay protein TusB/DsrH; The three proteins TusB, TusC, and TusD form a heterohexamer responsible for a sulfur relay reaction. In large numbers of proteobacterial species, this complex acts on a Cys-derived persulfide moiety, delivered by the cysteine desulfurase IscS to TusA, then to TusBCD. The activated sulfur group is then transferred to TusE (DsrC), then by MnmA (TrmU) for modification of an anticodon nucleotide in tRNAs for Glu, Lys, and Gln. The sulfur relay complex TusBCD is also found, under the designation DsrEFH, in phototrophic and chemotrophic sulfur bacteria, such as Chromatium vinosum. In these organisms, it seems the primary purpose is related to sulfur flux, such as oxidation from sulfide to molecular sulfur to sulfate. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 274388 [Multi-domain]  Cd Length: 94  Bit Score: 108.48  E-value: 1.76e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151   3 HTLSVSPWHAD-IAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYTD 81
Cdd:TIGR03011  1 HTVKKSPFEDNdLELCLRLLGPGDAILLLQDGVYAALEGNRYLSALLKAGVKVYALKEDLEARGLTDRLSDGVNVIDYTG 80

                         90
                 ....*....|....
gi 490307151  82 FVRLTVKHAGQLAW 95
Cdd:TIGR03011 81 FVELTEKHDKVITW 94
 
Name Accession Description Interval E-value
PRK13510 PRK13510
sulfurtransferase complex subunit TusB;
1-95 8.67e-53

sulfurtransferase complex subunit TusB;


Pssm-ID: 184101  Cd Length: 95  Bit Score: 159.76  E-value: 8.67e-53
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151  1 MLHTLSVSPWHADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYT 80
Cdd:PRK13510  1 MLHTLSRSPWLTDFAALLRLLKEGDDLLLLQDGVTAALKGNRFLESLRNAPIKLYALKEDLIARGLTGQISDSIILISYT 80

                        90
                ....*....|....*
gi 490307151 81 DFVRLTVKHAGQLAW 95
Cdd:PRK13510 81 DFVRLTVKHSQQMAW 95
TusB COG2168
Sulfur transfer complex TusBCD TusB component, DsrH family [Translation, ribosomal structure ...
 1-95 6.94e-41

Sulfur transfer complex TusBCD TusB component, DsrH family [Translation, ribosomal structure and biogenesis];


Pssm-ID: 441771  Cd Length: 96  Bit Score: 129.57  E-value: 6.94e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151  1 MLHTLSVSPWH-ADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSY 79
Cdd:COG2168   1 MLHTVSKSPFEtNDLDSCLRLLTPGDALLLIQDGVYAALKGSRALALLLAAPIKVYALKEDLEARGLTAQISDGVKLIDY 80

                        90
                ....*....|....*.
gi 490307151 80 TDFVRLTVKHAGQLAW 95
Cdd:COG2168  81 AGFVELTEKHDKQISW 96
DsrH pfam04077
DsrH like protein; DsrH is involved in oxidation of intracellular sulphur in the phototrophic ...
 8-92 1.47e-32

DsrH like protein; DsrH is involved in oxidation of intracellular sulphur in the phototrophic sulphur bacterium Chromatium vinosum D.


Pssm-ID: 461159  Cd Length: 87  Bit Score: 108.42  E-value: 1.47e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151   8 SPWH-ADIAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYTDFVRLT 86
Cdd:pfam04077  2 SPFEtNALDSCLRLLTPGDAVLLIQDGVYAALKGNRFLAALQAAGVKLYALKEDLEARGLSDQISPGVKVIDYDGFVDLT 81


                 ....*.
gi 490307151  87 VKHAGQ 92
Cdd:pfam04077 82 VKHDKV 87
sulf_tusB_dsrH TIGR03011
sulfur relay protein TusB/DsrH; The three proteins TusB, TusC, and TusD form a heterohexamer ...
 3-95 1.76e-32

sulfur relay protein TusB/DsrH; The three proteins TusB, TusC, and TusD form a heterohexamer responsible for a sulfur relay reaction. In large numbers of proteobacterial species, this complex acts on a Cys-derived persulfide moiety, delivered by the cysteine desulfurase IscS to TusA, then to TusBCD. The activated sulfur group is then transferred to TusE (DsrC), then by MnmA (TrmU) for modification of an anticodon nucleotide in tRNAs for Glu, Lys, and Gln. The sulfur relay complex TusBCD is also found, under the designation DsrEFH, in phototrophic and chemotrophic sulfur bacteria, such as Chromatium vinosum. In these organisms, it seems the primary purpose is related to sulfur flux, such as oxidation from sulfide to molecular sulfur to sulfate. [Protein synthesis, tRNA and rRNA base modification]


Pssm-ID: 274388 [Multi-domain]  Cd Length: 94  Bit Score: 108.48  E-value: 1.76e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490307151   3 HTLSVSPWHAD-IAAMLRLMEQGDDLLLLSDGVAAAIAGGRFLEILQSAPITLYVLQDDVDARGLTGQIADSVGRVSYTD 81
Cdd:TIGR03011  1 HTVKKSPFEDNdLELCLRLLGPGDAILLLQDGVYAALEGNRYLSALLKAGVKVYALKEDLEARGLTDRLSDGVNVIDYTG 80

                         90
                 ....*....|....
gi 490307151  82 FVRLTVKHAGQLAW 95
Cdd:TIGR03011 81 FVELTEKHDKVITW 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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