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Conserved domains on  [gi|490311659|ref|WP_004206354|]
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MULTISPECIES: glutamate/aspartate:proton symporter GltP [Klebsiella]

Protein Classification

proton/glutamate symporter( domain architecture ID 10013774)

proton/glutamate symporter, similar to E.coli GltP, imports glutamate coupled with the import of H+; belongs to the dicarboxylate/amino acid:cation symporter family

Gene Ontology:  GO:0005280|GO:0022857

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
3-437 0e+00

glutamate/aspartate:proton symporter; Provisional


:

Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 761.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659   3 KTKKVSLAWQILLALVLGILLGSYLHYHAESRDWLISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIG 82
Cdd:PRK11283   2 KNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  83 AKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQLAAVDISKYQNTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDML 162
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEML 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 163 PIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAI 242
Cdd:PRK11283 162 PIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFAI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 243 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQS 322
Cdd:PRK11283 242 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQS 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 323 IAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 402
Cdd:PRK11283 322 IAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 401
                        410       420       430
                 ....*....|....*....|....*....|....*
gi 490311659 403 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAQ 437
Cdd:PRK11283 402 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAD 436
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
3-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 761.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659   3 KTKKVSLAWQILLALVLGILLGSYLHYHAESRDWLISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIG 82
Cdd:PRK11283   2 KNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  83 AKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQLAAVDISKYQNTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDML 162
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEML 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 163 PIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAI 242
Cdd:PRK11283 162 PIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFAI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 243 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQS 322
Cdd:PRK11283 242 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQS 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 323 IAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 402
Cdd:PRK11283 322 IAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 401
                        410       420       430
                 ....*....|....*....|....*....|....*
gi 490311659 403 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAQ 437
Cdd:PRK11283 402 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAD 436
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
37-425 4.40e-159

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 454.96  E-value: 4.40e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  37 LISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTGIDMS 116
Cdd:COG1301   26 LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLD 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 117 QLAAVDISKyqnttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPAtHREPLVTVFRSISET 196
Cdd:COG1301  106 LADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQIIFFAILFGIALAALGE-KGKPLLDFFESLSEV 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 197 MFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVAR-LCGLSIWILIRILKDELILA 275
Cdd:COG1301  176 MFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLHLFVVLPLILRlLTGLSPLKFLRAIRPALLLA 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 276 YSTASSESVLPRIIEKM-EAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKG 354
Cdd:COG1301  256 FSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIG 335
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490311659 355 IAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKKALAYE 425
Cdd:COG1301  336 AAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGELDREKLNAAL 406
SDF pfam00375
Sodium:dicarboxylate symporter family;
38-412 8.37e-118

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 349.13  E-value: 8.37e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659   38 ISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQ 117
Cdd:pfam00375  22 LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIA 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  118 LAAVDISKyqnttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPaTHREPLVTVFRSISETM 197
Cdd:pfam00375 102 ASLKEAKA---------AEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFAILFGIALAALG-EKGEPLLNFIESLQEVM 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  198 FKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVAR-LCGLSIWILIRILKDELILAY 276
Cdd:pfam00375 172 MKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKfLGKVNPFKFLKKMLPALLTAF 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  277 STASSESVLPRIIEKME-AYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGI 355
Cdd:pfam00375 252 STASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGA 331
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 490311659  356 AGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKW 412
Cdd:pfam00375 332 AGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
 
Name Accession Description Interval E-value
gltP PRK11283
glutamate/aspartate:proton symporter; Provisional
3-437 0e+00

glutamate/aspartate:proton symporter; Provisional


Pssm-ID: 183075 [Multi-domain]  Cd Length: 437  Bit Score: 761.61  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659   3 KTKKVSLAWQILLALVLGILLGSYLHYHAESRDWLISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIG 82
Cdd:PRK11283   2 KNIKFSLAWQILIALVLGILLGAYLHYHSDSRDWLVSNLLSPAGDIFIHLIKMIVVPIVISTLIVGIAGVGDAKQLGRIG 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  83 AKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQLAAVDISKYQNTTAEVQSHAHGLMGTILSLVPTNIVASMAKGDML 162
Cdd:PRK11283  82 AKTIIYFEVITTVAIILGITLANVFQPGAGIDMSQLATVDISKYQSTTEEVQSHSHGLMGTILSLIPTNIFASMAKGEML 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 163 PIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAI 242
Cdd:PRK11283 162 PIIFFSVLFGLGLSSLPATHREPLVTVFRSVSETMFKVTHMVMRYAPVGVFALIAVTVANFGFASLWPLAKLVLLVYFAI 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 243 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQS 322
Cdd:PRK11283 242 LFFALVVLGIVARLCGLSIWILIRILKDELILAYSTASSETVLPRIIEKMEAYGAPKSITSFVVPTGYSFNLDGSTLYQS 321
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 323 IAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 402
Cdd:PRK11283 322 IAAIFIAQLYGIDLSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGN 401
                        410       420       430
                 ....*....|....*....|....*....|....*
gi 490311659 403 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAQ 437
Cdd:PRK11283 402 ALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTAD 436
GltP COG1301
Na+/H+-dicarboxylate symporter [Energy production and conversion];
37-425 4.40e-159

Na+/H+-dicarboxylate symporter [Energy production and conversion];


Pssm-ID: 440912 [Multi-domain]  Cd Length: 406  Bit Score: 454.96  E-value: 4.40e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  37 LISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTGIDMS 116
Cdd:COG1301   26 LVAAVLKPLGDIFINLLKMIVVPLVFFSIVVGIASLGDLKKLGRIGGKTLLYFLVTTTIALVIGLVVANLFQPGAGLNLD 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 117 QLAAVDISKyqnttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPAtHREPLVTVFRSISET 196
Cdd:COG1301  106 LADAAAAEA---------AEAPSLLDFLLNIIPSNIFEAFAEGNMLQIIFFAILFGIALAALGE-KGKPLLDFFESLSEV 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 197 MFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVAR-LCGLSIWILIRILKDELILA 275
Cdd:COG1301  176 MFKIVGWVMKLAPIGVFALIAATVAKYGLDALGSLGKLVLTVYLALLLHLFVVLPLILRlLTGLSPLKFLRAIRPALLLA 255
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 276 YSTASSESVLPRIIEKM-EAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKG 354
Cdd:COG1301  256 FSTSSSEATLPVTMEKAeEKLGVSKSVASFVLPLGATINMDGTAIYQAVAALFIAQAYGIDLSLGQQLTIVLTAVLASIG 335
                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490311659 355 IAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKKALAYE 425
Cdd:COG1301  336 AAGVPGAGLVMLAAVLSAVGLPLEGIALILGIDRILDMARTAVNVTGDAVATVVVAKWEGELDREKLNAAL 406
PRK01663 PRK01663
C4-dicarboxylate transporter DctA; Reviewed
42-421 4.69e-142

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 234968 [Multi-domain]  Cd Length: 428  Bit Score: 412.37  E-value: 4.69e-142
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  42 LTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTG--IDMSQLA 119
Cdd:PRK01663  34 MKPLGDGFIKLIKMIIAPIIFCTVVTGIAGMGDMKKVGRVGGKALLYFEIVSTIALIIGLIVVNVVQPGAGmnIDPATLD 113
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 120 AVDISKYQNttaevQSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPATHRePLVTVFRSISETMFK 199
Cdd:PRK01663 114 AKAVAQYAA-----QAHEQGTVDFLMDIIPTTVVGAFASGDILQVLLFAVLFGFALARLGEKGK-PVFDFIESLSHVLFG 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 200 VTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTA 279
Cdd:PRK01663 188 IVNMIMKLAPIGAFGAMAFTIGKYGVGSLVQLGQLIGCFYITCILFVFVVLGAIARLTGFSIFKFIRYIKEELLIVLGTS 267
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 280 SSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVP 359
Cdd:PRK01663 268 SSESALPRMMEKMEKLGCKKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNTPLSIGHQITLLAVLLLTSKGAAGVT 347
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490311659 360 GVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKKA 421
Cdd:PRK01663 348 GSGFIVLAATLSAVPhIPVAGLALILGIDRFMSEARALTNLIGNGVATVVVAKWEKELDREKL 410
PRK13027 PRK13027
C4-dicarboxylate transporter DctA; Reviewed
42-421 6.34e-119

C4-dicarboxylate transporter DctA; Reviewed


Pssm-ID: 183850 [Multi-domain]  Cd Length: 421  Bit Score: 353.20  E-value: 6.34e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  42 LTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTG--IDMSQLA 119
Cdd:PRK13027  33 LKPLGDGFIKLIKMLIGPIVFCVVVSGIAGAGDLKKVGRVGLKAVIYFEVMTTIALVIGLVLAYLTGPGVGmnIDLRSLD 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 120 AVDISKYqnttAEVQSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPATHRePLVTVFRSISETMFK 199
Cdd:PRK13027 113 AASLAGY----AKNAQSLKGTAGFLLKLIPTTAVDAFAKGDILQVLLFSVLFGSALSLLGERAK-RVNRLIDELSHVLFR 187
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 200 VTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVARLCGLSIWILIRILKDELILAYSTA 279
Cdd:PRK13027 188 IMGFIIKLAPLGVLGAIAFTTGKYGVGSLKQLGMLVAVFYLTCFVFVVVVLGAVMRLAGFSVFKLIRYLREELLIVLGTA 267
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 280 SSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVP 359
Cdd:PRK13027 268 SSDAVLPQVMRKLEHMGIKDSTVGLVIPTGYSFNLDGFSIYLTLAAVFIAQATNTPLSMHDLITILLVSLVTSKGAHGIP 347
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490311659 360 GVSFVVLLATLGSVG-IPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKKA 421
Cdd:PRK13027 348 GSAIVILAATLSAIPaIPVLGLVLILPVDWFMGIARALTNLIGNCVATVVVAVWENDIDRARA 410
SDF pfam00375
Sodium:dicarboxylate symporter family;
38-412 8.37e-118

Sodium:dicarboxylate symporter family;


Pssm-ID: 425646 [Multi-domain]  Cd Length: 388  Bit Score: 349.13  E-value: 8.37e-118
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659   38 ISNLLTPAGDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPGTGIDMSQ 117
Cdd:pfam00375  22 LAAWLKPLGDLFIRLLKMIIVPLIFASIISGIASLGDGKKLGKLGGKTLLYFLVTTAIAALIGLLVANVFQPGSGLALIA 101
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  118 LAAVDISKyqnttaevqSHAHGLMGTILSLVPTNIVASMAKGDMLPIIFFSVLFGLGLSSLPaTHREPLVTVFRSISETM 197
Cdd:pfam00375 102 ASLKEAKA---------AEAPSLLDFILNIIPSNIFEALAEGNVLAVIVFAILFGIALAALG-EKGEPLLNFIESLQEVM 171
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  198 FKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVAR-LCGLSIWILIRILKDELILAY 276
Cdd:pfam00375 172 MKVIGWVMKLAPIGVFALIANTVGTYGLGILSSLAKFLLVVYLGLAIHLLIVYPLLIKfLGKVNPFKFLKKMLPALLTAF 251
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  277 STASSESVLPRIIEKME-AYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGI 355
Cdd:pfam00375 252 STASSAATLPVTLECAEkNLGVSESIASFVLPLGATINMDGTAIYLAVAAIFIAQAYGVDLSFGQQLTLVLTATLASIGA 331
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|....*..
gi 490311659  356 AGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKW 412
Cdd:pfam00375 332 AGVPGGGLVALGLVLSALGLPLEGIALILAIDRLLDMFRTAVNVTGDAAAAVIVAKL 388
TcyP COG1823
L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and ...
46-420 1.32e-32

L-cystine transporter TcyP, sodium:dicarboxylate symporter family [Amino acid transport and metabolism];


Pssm-ID: 441428  Cd Length: 463  Bit Score: 128.41  E-value: 1.32e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  46 GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFqpgtGIDMSQLAAVD--- 122
Cdd:COG1823   70 GNGYVRLLQMIVMPLVFVSILSAITKLKNASSLGKISGLIIGILLGTTAIAALVGILVALLF----GLTAEGLTQGAaet 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 123 --ISKYQNTTAEVQSHAhgLMGTILSLVPTNIVASMAKGDMLPII---FFSVLFG---LGLSSLPATHREPLVTVFRSIS 194
Cdd:COG1823  146 arGEALEERLGEVEDLS--LPQQILSFIPTNPFADLTGARPTSTIavvIFAAFLGiaaLGLRRKKPEQAETFLKGIDALQ 223
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 195 ETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVArLCGLSIWILIRILKDELIL 274
Cdd:COG1823  224 AIVMRLVRLVLRLTPYGVLALMTKVVATSDFADILNLGKFVVASYVALIIMFIVHLLLLA-LAGLNPLTYFKKVWPVLTF 302
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 275 AYSTASSESVLPRIIE-KMEAYGAPASITSFVVPTGYSFNLDG-STLYQSIAAIFIAQLYGID-LSIWQEITLVLTLMVT 351
Cdd:COG1823  303 AFTSRSSAGTIPLNIEtQTKRLGVPEGIANFAASFGATIGQNGcAGIYPAMLAVMIAPTVGINpLDPSFILTLIAVVTIS 382
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490311659 352 SKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMARTALNVVGNALAVLVIAKWEHKFDRKK 420
Cdd:COG1823  383 SFGVAGVGGGATFAALIVLSAMGLPVALAGLLISIEPLIDMGRTALNVSGSMTAGTVTSRLLGQLDKDI 451
SstT COG3633
Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];
46-398 2.67e-15

Na+/serine and Na+/threonine symporter SstT [Amino acid transport and metabolism];


Pssm-ID: 442850  Cd Length: 406  Bit Score: 77.13  E-value: 2.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659  46 GDIFIHLIKMiVVPIVISTLVvgIAGVGDAKQLGRIGAKTIIYFEVITTVAIVLGITLANVFQPgTGIDMsQLAAVDISK 125
Cdd:COG3633   44 GTLFVGALKA-VAPILVFVLV--MSAIANHKQGQKTNMKPIIVLYLLGTFLAALVAVVASFLFP-TTLTL-VAAAADLTP 118
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 126 YQNTtAEVqshahgLMGTILSLVpTNIVASMAKGDMLPIIFFSVLFGLGLSSLPATHReplvTVFRSISETMFKVTHMVM 205
Cdd:COG3633  119 PGGI-GEV------LKTLLLNVV-DNPVNALANANYIGILAWAIGLGLALRHASDTTK----TVLSDLSDAVSKIVRWVI 186
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 206 RYAPIGVFALISVTVATFGFASLWPLAKLVLLVYFAILFFALVVLGIVarlcglsIWILIRI---------LKDELILAY 276
Cdd:COG3633  187 RFAPLGIFGLVASTVATTGFSALLGYAHLLAVLVGCMLFVALVVNPLI-------VFLKIRRnpyplvftcLRESGITAF 259
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 277 STASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGstlyqsiAAIFIAQL-------YGIDLSIWQEITLVLTLM 349
Cdd:COG3633  260 FTRSSAANIPVNMALCEKLGLDEDTYSVSIPLGATINMAG-------AAITITVLtlaavhtLGIEVDLPTALLLSVVAA 332
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 490311659 350 VTSKGIAGVPGVSfvVLLATL--GSVGIPLE------GLAFIAGVdrILDMARTALN 398
Cdd:COG3633  333 VSACGASGVAGGS--LLLIPLacSLFGISNDiamqvvAVGFIIGV--IQDSAETALN 385
PRK13628 PRK13628
serine/threonine transporter SstT; Provisional
140-398 5.09e-14

serine/threonine transporter SstT; Provisional


Pssm-ID: 184190 [Multi-domain]  Cd Length: 402  Bit Score: 73.36  E-value: 5.09e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 140 LMGTILSLVpTNIVASMAKGDMLPIIFFSVLFGLGLSSLPATHReplvTVFRSISETMFKVTHMVMRYAPIGVFALISVT 219
Cdd:PRK13628 127 LKTLLLSLV-DNPINALLNANYIGILAWAIGLGLALRHASDTTK----NVVNDLSEAVSQIVKWVIRFAPIGIFGLVAST 201
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 220 VATFGFASLWPLAKLVLLVYFAILFFALVVLGIVarlcglsIWILIR---------ILKDELILAYSTASSESVLPRIIE 290
Cdd:PRK13628 202 LAETGFSALAGYAQLLAVLVGCMLFVALVVNPLI-------VFWKIRrnpyplvftCLRESGVTAFFTRSSAANIPVNMA 274
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 291 KMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVVLLATL 370
Cdd:PRK13628 275 LCEKLGLDEDTYSVSIPLGATINMAGAAITITVLTLAAVHTLGIPVDLPTALLLSVVAAISACGASGVAGGSLLLIPLAC 354
                        250       260       270
                 ....*....|....*....|....*....|....
gi 490311659 371 GSVGIPLE------GLAFIAGVdrILDMARTALN 398
Cdd:PRK13628 355 SLFGISNDiamqvvAVGFIIGV--LQDSAETALN 386
PRK14695 PRK14695
serine/threonine transporter SstT; Provisional
153-420 1.98e-07

serine/threonine transporter SstT; Provisional


Pssm-ID: 173158  Cd Length: 319  Bit Score: 52.36  E-value: 1.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 153 VASMAKGDMLPIIFFSVLFGLGLSSLPATHREplvtVFRSISETMFKVTHMVMRYAPIGVFALISVTVATFGFASLWPLA 232
Cdd:PRK14695  53 VNALLTANYIGILSWAVIFGIAMREASKNSKE----LLKTIADVTSKIVEWIINLAPFGILGLVFKTISDKGVGSLANYG 128
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 233 KLVLLVYFAILFFALVVLGIVA-----RLCGLSIWILIRIlkdELILAYSTASSESVLPRIIEKMEAYGAPASITSFVVP 307
Cdd:PRK14695 129 ILLVLLVTTMLFVAPVVNPLIAfffmrRNPYPLVWNCLRV---SGVTAFFTRSSATNIPVNMKLCHDLGLNPDTYSVSIP 205
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490311659 308 TGYSFNLDGSTLYQSIAAIFIAQLYGIDLSIWQEITLVLTLMVTSKGIAGVPGVSFVV------LLATLGSVGIPLEGLA 381
Cdd:PRK14695 206 LGSTINMAGVAITINLLTLVTVNTLGIPVDFATAFVLSVVAAISACGASGIAGGSLLLipvacsLFGISNDIAIQIVGVG 285
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 490311659 382 FIAGVdrILDMARTALNvvgNALAVLVIAKWEHKFDRKK 420
Cdd:PRK14695 286 FVIGV--IQDSCETALN---SSTDVLFTAVAEYAATRKK 319
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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