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Conserved domains on  [gi|490362885|ref|WP_004242629|]
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MULTISPECIES: helix-turn-helix domain-containing protein [Proteus]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RobA_TF super family cl41266
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as ...
 4-105 1.11e-39

MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.


The actual alignment was detected with superfamily member NF012228:

Pssm-ID: 467958 [Multi-domain]  Cd Length: 286  Bit Score: 133.49  E-value: 1.11e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   4 NVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:NF012228   3 GIIRDLLVWLEGHLDQP--LSLDNVAAKAGYSKWHLQRMFKDVTGQAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 80

                         90       100
                 ....*....|....*....|..
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFR 105
Cdd:NF012228  81 DSQQTFTRAFKKQFNQTPALYR 102
 
Name Accession Description Interval E-value
RobA_TF NF012228
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as ...
 4-105 1.11e-39

MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.


Pssm-ID: 467958 [Multi-domain]  Cd Length: 286  Bit Score: 133.49  E-value: 1.11e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   4 NVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:NF012228   3 GIIRDLLVWLEGHLDQP--LSLDNVAAKAGYSKWHLQRMFKDVTGQAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 80

                         90       100
                 ....*....|....*....|..
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFR 105
Cdd:NF012228  81 DSQQTFTRAFKKQFNQTPALYR 102
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
4-105 1.34e-38

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 130.90  E-value: 1.34e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   4 NVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:PRK15121   5 GIIRDLLIWLEGHLDQP--LSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 82

                         90       100
                 ....*....|....*....|..
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFR 105
Cdd:PRK15121  83 DSQQTFTRAFKKQFAQTPALYR 104
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
22-105 5.54e-33

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 110.34  E-value: 5.54e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885    22 GIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTP 101
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 490362885   102 AKFR 105
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
13-107 1.29e-29

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 107.17  E-value: 1.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  13 LETQLQRNEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRI 92
Cdd:COG2207  159 LLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRA 238

                         90
                 ....*....|....*
gi 490362885  93 FKKHFNTTPAKFREH 107
Cdd:COG2207  239 FKKRFGVTPSEYRKR 253
HTH_18 pfam12833
Helix-turn-helix domain;
28-106 3.69e-26

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 93.04  E-value: 3.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   28 IANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSL-QEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAKFRE 106
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
 
Name Accession Description Interval E-value
RobA_TF NF012228
MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as ...
 4-105 1.11e-39

MDR efflux pump AcrAB transcriptional activator RobA; The original characterization of RobA as a Right side Origin of replication Binding protein A (robA) may be misleading. Characterizations in large numbers of papers since then treat RobA as a transcriptional activator of the AcrAB antibiotic efflux pump.


Pssm-ID: 467958 [Multi-domain]  Cd Length: 286  Bit Score: 133.49  E-value: 1.11e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   4 NVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:NF012228   3 GIIRDLLVWLEGHLDQP--LSLDNVAAKAGYSKWHLQRMFKDVTGQAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 80

                         90       100
                 ....*....|....*....|..
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFR 105
Cdd:NF012228  81 DSQQTFTRAFKKQFNQTPALYR 102
PRK15121 PRK15121
MDR efflux pump AcrAB transcriptional activator RobA;
4-105 1.34e-38

MDR efflux pump AcrAB transcriptional activator RobA;


Pssm-ID: 185076 [Multi-domain]  Cd Length: 289  Bit Score: 130.90  E-value: 1.34e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   4 NVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:PRK15121   5 GIIRDLLIWLEGHLDQP--LSLDNVAAKAGYSKWHLQRMFKDVTGHAIGAYIRARRLSKAAVALRLTSRPILDIALQYRF 82

                         90       100
                 ....*....|....*....|..
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFR 105
Cdd:PRK15121  83 DSQQTFTRAFKKQFAQTPALYR 104
PRK10219 PRK10219
superoxide response transcriptional regulator SoxS;
1-105 4.56e-33

superoxide response transcriptional regulator SoxS;


Pssm-ID: 182314 [Multi-domain]  Cd Length: 107  Bit Score: 111.56  E-value: 4.56e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   1 MAENVVNDILKWLETQLqrNEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALM 80
Cdd:PRK10219   2 SHQKIIQTLIAWIDEHI--DQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMD 79

                         90       100
                 ....*....|....*....|....*
gi 490362885  81 YGFSSQATFTRIFKKHFNTTPAKFR 105
Cdd:PRK10219  80 LGYVSQQTFSRVFRRQFDRTPSDYR 104
HTH_ARAC smart00342
helix_turn_helix, arabinose operon control protein;
22-105 5.54e-33

helix_turn_helix, arabinose operon control protein;


Pssm-ID: 197666 [Multi-domain]  Cd Length: 84  Bit Score: 110.34  E-value: 5.54e-33
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885    22 GIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTP 101
Cdd:smart00342   1 PLTLEDLAEALGVSPRHLQRLFKKETGTTPKQYLRDRRLERARRLLRDTDLSVTEIALRVGFSSQSYFSRAFKKLFGVTP 80


                   ....
gi 490362885   102 AKFR 105
Cdd:smart00342  81 SEYR 84
AraC COG2207
AraC-type DNA-binding domain and AraC-containing proteins [Transcription];
13-107 1.29e-29

AraC-type DNA-binding domain and AraC-containing proteins [Transcription];


Pssm-ID: 441809 [Multi-domain]  Cd Length: 258  Bit Score: 107.17  E-value: 1.29e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  13 LETQLQRNEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRI 92
Cdd:COG2207  159 LLLLLLLLLLLTLEELARELGLSPRTLSRLFKEETGTSPKQYLRELRLERAKRLLAETDLSISEIAYELGFSSQSHFSRA 238

                         90
                 ....*....|....*
gi 490362885  93 FKKHFNTTPAKFREH 107
Cdd:COG2207  239 FKKRFGVTPSEYRKR 253
PRK11511 PRK11511
MDR efflux pump AcrAB transcriptional activator MarA;
6-105 6.47e-28

MDR efflux pump AcrAB transcriptional activator MarA;


Pssm-ID: 236920 [Multi-domain]  Cd Length: 127  Bit Score: 99.02  E-value: 6.47e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   6 VNDILKWLETQLQrnEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSS 85
Cdd:PRK11511  11 IHSILDWIEDNLE--SPLSLEKVSERSGYSKWHLQRMFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFES 88

                         90       100
                 ....*....|....*....|
gi 490362885  86 QATFTRIFKKHFNTTPAKFR 105
Cdd:PRK11511  89 QQTLTRTFKNYFDVPPHKYR 108
HTH_18 pfam12833
Helix-turn-helix domain;
28-106 3.69e-26

Helix-turn-helix domain;


Pssm-ID: 432818 [Multi-domain]  Cd Length: 81  Bit Score: 93.04  E-value: 3.69e-26
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   28 IANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSL-QEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAKFRE 106
Cdd:pfam12833   1 LAAALGMSPRTLSRLFKRELGLSPKEYLRRLRLERARRLLlEDTGLSVAEIALALGFSDASHFSRAFRRLFGLTPSEYRR 80
GlxA COG4977
Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH ...
 6-106 3.43e-21

Transcriptional regulator GlxA, contains an amidase domain and an AraC-type DNA-binding HTH domain [Transcription];


Pssm-ID: 444002 [Multi-domain]  Cd Length: 318  Bit Score: 85.98  E-value: 3.43e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   6 VNDILKWLETQLQrnEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSS 85
Cdd:COG4977  212 LARAQAWMEANLE--EPLSVDELARRAGMSPRTLERRFRAATGTTPARYLQRLRLERARRLLETTDLSIEEIAAACGFGS 289

                         90       100
                 ....*....|....*....|.
gi 490362885  86 QATFTRIFKKHFNTTPAKFRE 106
Cdd:COG4977  290 ASHFRRAFRRRFGVSPSAYRR 310
AdaA COG2169
Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), ...
 2-116 1.31e-19

Methylphosphotriester-DNA--protein-cysteine methyltransferase (N-terminal fragment of Ada), contains Zn-binding and two AraC-type DNA-binding domains [Replication, recombination and repair];


Pssm-ID: 441772 [Multi-domain]  Cd Length: 358  Bit Score: 82.02  E-value: 1.31e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   2 AENVVNDILKWLETQLQrnEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEkDMSILDIALMY 81
Cdd:COG2169   82 RADLVARACRLIEAGAE--DRPSLEDLAARLGLSPRHLRRLFKAHTGVTPKAYARARRLLRARQLLQT-GLSVTDAAYAA 158

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490362885  82 GFSSQATFTRIFKKHFNTTPAKFREHGELPDTRRF 116
Cdd:COG2169  159 GFGSLSRFYEAFKKLLGMTPSAYRRGGAGAAIRFA 193
PRK09685 PRK09685
DNA-binding transcriptional activator FeaR; Provisional
 16-105 7.49e-14

DNA-binding transcriptional activator FeaR; Provisional


Pssm-ID: 236612 [Multi-domain]  Cd Length: 302  Bit Score: 65.82  E-value: 7.49e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  16 QLQRNEGIKIDTIANKSGYSKWHLQRIFKDfKGCTLGEYVRKRRLLEAAKSLQE--KDMSILDIALMYGFSSQATFTRIF 93
Cdd:PRK09685 208 QSIQEEILRPEWIAGELGISVRSLYRLFAE-QGLVVAQYIRNRRLDRCADDLRPaaDDEKITSIAYKWGFSDSSHFSTAF 286

                         90
                 ....*....|..
gi 490362885  94 KKHFNTTPAKFR 105
Cdd:PRK09685 287 KQRFGVSPGEYR 298
ftrA PRK09393
transcriptional activator FtrA; Provisional
 9-106 2.75e-11

transcriptional activator FtrA; Provisional


Pssm-ID: 181818 [Multi-domain]  Cd Length: 322  Bit Score: 58.82  E-value: 2.75e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   9 ILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQAT 88
Cdd:PRK09393 223 LIDWMRAHLAEP--HTVASLAARAAMSPRTFLRRFEAATGMTPAEWLLRERLARARDLLESSALSIDQIAERAGFGSEES 300

                         90
                 ....*....|....*...
gi 490362885  89 FTRIFKKHFNTTPAKFRE 106
Cdd:PRK09393 301 LRHHFRRRAATSPAAYRK 318
PRK13503 PRK13503
HTH-type transcriptional activator RhaS;
6-105 1.29e-10

HTH-type transcriptional activator RhaS;


Pssm-ID: 184094 [Multi-domain]  Cd Length: 278  Bit Score: 56.61  E-value: 1.29e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   6 VNDILKWLETQLQrnEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSS 85
Cdd:PRK13503 173 LNQLLAWLEDHFA--EEVNWEALADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLLKARHLLRHSDASVTDIAYRCGFGD 250

                         90       100
                 ....*....|....*....|
gi 490362885  86 QATFTRIFKKHFNTTPAKFR 105
Cdd:PRK13503 251 SNHFSTLFRREFSWSPRDIR 270
PRK10371 PRK10371
transcriptional regulator MelR;
20-115 2.73e-09

transcriptional regulator MelR;


Pssm-ID: 182416 [Multi-domain]  Cd Length: 302  Bit Score: 53.28  E-value: 2.73e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  20 NEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNT 99
Cdd:PRK10371 205 DQALTINDVAEHVKLNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYSTFGKYVGM 284

                         90
                 ....*....|....*.
gi 490362885 100 TPAKFRehgELPDTRR 115
Cdd:PRK10371 285 SPQQYR---KLSQQRR 297
PRK10572 PRK10572
arabinose operon transcriptional regulator AraC;
23-106 1.25e-08

arabinose operon transcriptional regulator AraC;


Pssm-ID: 236717 [Multi-domain]  Cd Length: 290  Bit Score: 51.13  E-value: 1.25e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  23 IKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPA 102
Cdd:PRK10572 200 FDIESVAQHVCLSPSRLAHLFRQQLGISVLRWREDQRISRAKLLLQTTRMPIATIGRNVGYDDQLYFSRVFKKCTGASPS 279


                 ....
gi 490362885 103 KFRE 106
Cdd:PRK10572 280 EFRA 283
PRK15186 PRK15186
AraC family transcriptional regulator; Provisional
 1-104 3.29e-07

AraC family transcriptional regulator; Provisional


Pssm-ID: 185108 [Multi-domain]  Cd Length: 291  Bit Score: 47.37  E-value: 3.29e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   1 MAENVVNDILkwleTQLQRNEGIKidTIANKSGYSKWHLQRIFKDfKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALM 80
Cdd:PRK15186 182 LAENIYNIII----SDISRKWALK--DISDSLYMSCSTLKRKLKQ-ENTSFSEVYLNARMNKATKLLRNSEYNITRVAYM 254

                         90       100
                 ....*....|....*....|....
gi 490362885  81 YGFSSQATFTRIFKKHFNTTPAKF 104
Cdd:PRK15186 255 CGYDSASYFTCVFKKHFKTTPSEF 278
HTH_AraC pfam00165
Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the ...
 71-105 4.25e-06

Bacterial regulatory helix-turn-helix proteins, AraC family; In the absence of arabinose, the N-terminal arm of AraC binds to the DNA binding domain (pfam00165) and helps to hold the two DNA binding domains in a relative orientation that favours DNA looping. In the presence of arabinose, the arms bind over the arabinose on the dimerization domain, thus freeing the DNA-binding domains. The freed DNA-binding domains are then able to assume a conformation suitable for binding to the adjacent DNA sites that are utilized when AraC activates transcription, and hence AraC ceases looping the DNA when arabinose is added.


Pssm-ID: 425497 [Multi-domain]  Cd Length: 42  Bit Score: 40.60  E-value: 4.25e-06
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 490362885   71 DMSILDIALMYGFSSQaTFTRIFKKHFNTTPAKFR 105
Cdd:pfam00165   8 NLTIADIADELGFSRS-YFSRLFKKYTGVTPSQYR 41
PRK15185 PRK15185
transcriptional regulator HilD; Provisional
 24-104 6.07e-06

transcriptional regulator HilD; Provisional


Pssm-ID: 185107 [Multi-domain]  Cd Length: 309  Bit Score: 43.45  E-value: 6.07e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  24 KIDTIANKSGYSKWHLQRIFKDfKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAK 103
Cdd:PRK15185 224 KLTDVADHIFMSTSTLKRKLAE-EGTSFSDIYLSARMNQAAKLLRIGNHNVNAVALKCGYDSTSYFIQCFKKYFKTTPST 302


                 .
gi 490362885 104 F 104
Cdd:PRK15185 303 F 303
PRK13501 PRK13501
HTH-type transcriptional activator RhaR;
39-106 7.05e-06

HTH-type transcriptional activator RhaR;


Pssm-ID: 184092 [Multi-domain]  Cd Length: 290  Bit Score: 43.35  E-value: 7.05e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490362885  39 LQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAKFRE 106
Cdd:PRK13501 209 LKQLFRQQTGMSISHYLRQIRLCHAKCLLRGSEHRISDIAARCGFEDSNYFSAVFTREAGMTPRDYRQ 276
PRK13500 PRK13500
HTH-type transcriptional activator RhaR;
2-105 1.27e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184091 [Multi-domain]  Cd Length: 312  Bit Score: 42.78  E-value: 1.27e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   2 AENVVNDILKWLETQLQrnEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMY 81
Cdd:PRK13500 204 SETLLDKLITRLAASLK--SPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTEC 281

                         90       100
                 ....*....|....*....|....
gi 490362885  82 GFSSQATFTRIFKKHFNTTPAKFR 105
Cdd:PRK13500 282 GFEDSNYFSVVFTRETGMTPSQWR 305
PRK13502 PRK13502
HTH-type transcriptional activator RhaR;
3-105 1.64e-05

HTH-type transcriptional activator RhaR;


Pssm-ID: 184093 [Multi-domain]  Cd Length: 282  Bit Score: 42.35  E-value: 1.64e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885   3 ENVVNDILKWLETQLQRNegIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYG 82
Cdd:PRK13502 175 ETLLDKLITALANSLECP--FALDAFCQQEQCSERVLRQQFRAQTGMTINQYLRQVRICHAQYLLQHSPLMISEISMQCG 252

                         90       100
                 ....*....|....*....|...
gi 490362885  83 FSSQATFTRIFKKHFNTTPAKFR 105
Cdd:PRK13502 253 FEDSNYFSVVFTRETGMTPSQWR 275
PRK15435 PRK15435
bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;
17-109 3.33e-05

bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada;


Pssm-ID: 185333 [Multi-domain]  Cd Length: 353  Bit Score: 41.70  E-value: 3.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  17 LQRNEGIKIDTIANKSGYSKWHLQRIFKDFKGCTLGEY---VRKRRLLEAAkslqEKDMSILDIALMYGFSSQATFTRIF 93
Cdd:PRK15435  94 LEQETPVTLEALADQVAMSPFHLHRLFKATTGMTPKAWqqaWRARRLREAL----AKGESVTTSILNAGFPDSSSYYRKA 169

                         90
                 ....*....|....*.
gi 490362885  94 KKHFNTTPAKFREHGE 109
Cdd:PRK15435 170 DETLGMTAKQFRHGGE 185
PRK09978 PRK09978
DNA-binding transcriptional regulator GadX; Provisional
 17-118 3.71e-04

DNA-binding transcriptional regulator GadX; Provisional


Pssm-ID: 137624 [Multi-domain]  Cd Length: 274  Bit Score: 38.37  E-value: 3.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490362885  17 LQRNEGIKIDTIANKSGYSKWHLQRIFKDF-------------KGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGF 83
Cdd:PRK09978 139 LQPNMRTRVCTVINNNIAHEWTLARIASELlmspsllkkklreEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY 218

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 490362885  84 SSQATFTRIFKKHFNTTPAKFRE----HGELPDTRRFMS 118
Cdd:PRK09978 219 HSVSYFIYVFRNYYGMTPTEYQErsaqGLPNRDSAASIV 257
PRK10296 PRK10296
DNA-binding transcriptional regulator ChbR; Provisional
 32-107 6.46e-04

DNA-binding transcriptional regulator ChbR; Provisional


Pssm-ID: 182362 [Multi-domain]  Cd Length: 278  Bit Score: 37.81  E-value: 6.46e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490362885  32 SGYSKWHLQRIFKDFKGCTLGEYVRKRRLLEAAKSLQEKDMSILDIALMYGFSSQATFTRIFKKHFNTTPAKFREH 107
Cdd:PRK10296 198 SGKSQEYLTRATRRYYGKTPMQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPGSYRKK 273
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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