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Conserved domains on  [gi|490365282|ref|WP_004244946|]
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MULTISPECIES: choline BCCT transporter BetT [Proteus]

Protein Classification

BCCT family transporter( domain architecture ID 2807)

BCCT (betaine-carnitine-choline transporter) family transporter shares the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]; energized by pmf-driven proton symport; similar to Escherichia coli secondary glycine betaine transporter BetU

Gene Ontology:  GO:0071705|GO:0022857|GO:0016020
PubMed:  20923416

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK09928 super family cl00569
choline transport protein BetT; Provisional
6-663 0e+00

choline transport protein BetT; Provisional


The actual alignment was detected with superfamily member PRK09928:

Pssm-ID: 469825  Cd Length: 679  Bit Score: 714.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   6 EITPKKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKL 85
Cdd:PRK09928   5 DLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  86 GPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILA 165
Cdd:PRK09928  85 GPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALG 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 166 FFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVIT 245
Cdd:PRK09928 165 YFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSV 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 246 GLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPkSSDWLGGWTL 325
Cdd:PRK09928 245 IIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWMNNWTL 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 326 LYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDkGAEVLANIVQQDVSLALFEFL 405
Cdd:PRK09928 324 FFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 406 NYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLAS---GGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIA 482
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSklkDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 483 SALPFAIVLLASIYGLIKALRVDVYKRDSQQMTTIAPPASRN-PIPWQRRLRNIAYFPKRSHVKRFMEEVVNPSMEMVSA 561
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQdRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 562 ELSKQGIQCYIHD---EEEDRIG---FEVDLGEDMNFFYEVRLRFYTQPAFALAGltdeeKDEEHKYYRAEIHLKEGGQD 635
Cdd:PRK09928 563 ELRLRGAYVELNElppEEDERLGhldLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKSTYYRLETFLLEGSQG 637
                        650       660
                 ....*....|....*....|....*...
gi 490365282 636 YDVMGWTKEQIIHDILDQYEKHIHFLHV 663
Cdd:PRK09928 638 NDLMDYSKEQVINDILDQYERHLNFLHL 665
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
6-663 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 714.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   6 EITPKKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKL 85
Cdd:PRK09928   5 DLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  86 GPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILA 165
Cdd:PRK09928  85 GPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALG 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 166 FFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVIT 245
Cdd:PRK09928 165 YFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSV 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 246 GLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPkSSDWLGGWTL 325
Cdd:PRK09928 245 IIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWMNNWTL 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 326 LYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDkGAEVLANIVQQDVSLALFEFL 405
Cdd:PRK09928 324 FFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 406 NYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLAS---GGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIA 482
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSklkDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 483 SALPFAIVLLASIYGLIKALRVDVYKRDSQQMTTIAPPASRN-PIPWQRRLRNIAYFPKRSHVKRFMEEVVNPSMEMVSA 561
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQdRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 562 ELSKQGIQCYIHD---EEEDRIG---FEVDLGEDMNFFYEVRLRFYTQPAFALAGltdeeKDEEHKYYRAEIHLKEGGQD 635
Cdd:PRK09928 563 ELRLRGAYVELNElppEEDERLGhldLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKSTYYRLETFLLEGSQG 637
                        650       660
                 ....*....|....*....|....*...
gi 490365282 636 YDVMGWTKEQIIHDILDQYEKHIHFLHV 663
Cdd:PRK09928 638 NDLMDYSKEQVINDILDQYERHLNFLHL 665
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-516 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 703.83  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   1 MSQQNeitPKKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRF 80
Cdd:COG1292    1 MSDKN---KEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKY 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  81 GEIKLGPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTG-DAQTIEAAKEAMRLTFFHWGLHAWAIYAI 159
Cdd:COG1292   78 GKIRLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 160 VALILAFFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVV 239
Cdd:COG1292  158 VGLALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQII 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 240 LIVVITGLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPksSDW 319
Cdd:COG1292  238 IIAVITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGW 315
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 320 LGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDkGAEVLANIVQQDVSL 399
Cdd:COG1292  316 LGGWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEA 394
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 400 ALFEFLNYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLASGGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTV 479
Cdd:COG1292  395 ALFALLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTA 474
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 490365282 480 TIASALPFAIVLLASIYGLIKALRVDVYKRDSQQMTT 516
Cdd:COG1292  475 SIITALPFSFVLLLMCVSLVKALREDPRRLRSAEAEA 511
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
20-505 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 634.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   20 VFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKLGPDHARPHFSYFAW 99
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  100 FAMLFSAGMGIGLMFFGVAEPVMHYL-MPPTGDAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLR 178
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLsPPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  179 SALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVITGLATISVVSGLEK 258
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  259 GIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPkSSDWLGGWTLLYWGWWLSWSPFV 338
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  339 GMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDKGAEvLANIVQQDVSLALFEFLNYFPFSSVLSFVA 418
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGD-LADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  419 MLMVIVFFVTSADSGAMVVDTLASGGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIASALPFAIVLLASIYGL 498
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 490365282  499 IKALRVD 505
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
58-505 8.36e-170

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 493.02  E-value: 8.36e-170
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   58 SWFYILAVALVLLSVTYLGLSRFGEIKLGPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDAQTIEA 137
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  138 AKE-AMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFG 216
Cdd:TIGR00842  81 AQEqALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  217 VLQVNAGLNHLFDIPINPTVQVVLIVVITGLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTG 296
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  297 GYLSEIVSKTFNLYAYEPKSSdWLGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNT 376
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  377 AIYLIKDKGAEVLANIVQQDVSLALFEFLNYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLASGG---DSETPVWQR 453
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490365282  454 IFWAALMGISAITLLLA-GGLSALQTVTIASALPFAIVLLASIYGLIKALRVD 505
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
 
Name Accession Description Interval E-value
PRK09928 PRK09928
choline transport protein BetT; Provisional
6-663 0e+00

choline transport protein BetT; Provisional


Pssm-ID: 236635  Cd Length: 679  Bit Score: 714.16  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   6 EITPKKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKL 85
Cdd:PRK09928   5 DLSHKREKDRINPVVFYTSAGLILLFSLTTILFTDFSNRWINRTLNWVSKTFGWYYLLAATLYIVFVIFIACSRFGSIKL 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  86 GPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILA 165
Cdd:PRK09928  85 GPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALG 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 166 FFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVIT 245
Cdd:PRK09928 165 YFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPESLAAQAALIALSV 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 246 GLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPkSSDWLGGWTL 325
Cdd:PRK09928 245 IIATISVTSGVNKGIRVLSELNVLLALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDR-PTEWMNNWTL 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 326 LYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDkGAEVLANIVQQDVSLALFEFL 405
Cdd:PRK09928 324 FFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSIFGNSALYEIIH-GNAAFAEEAMAHPERGFYSLL 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 406 NYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLAS---GGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIA 482
Cdd:PRK09928 403 AQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSklkDINSDAPNWLRVFWSVAIGLLTLGMLMTNGISALQNTTVI 482
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 483 SALPFAIVLLASIYGLIKALRVDVYKRDSQQMTTIAPPASRN-PIPWQRRLRNIAYFPKRSHVKRFMEEVVNPSMEMVSA 561
Cdd:PRK09928 483 MGLPFSFVIFFVMAGLYKSLKVEDYRRASANRDTAPRLVGLQdRLNWKQRLSRVMNYPGTRYTRRMLDTVCRPAMEEVAQ 562
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 562 ELSKQGIQCYIHD---EEEDRIG---FEVDLGEDMNFFYEVRLRFYTQPAFALAGltdeeKDEEHKYYRAEIHLKEGGQD 635
Cdd:PRK09928 563 ELRLRGAYVELNElppEEDERLGhldLLVHLGDEQNFVYQIWPQRYSVPGFTYRA-----RSGKSTYYRLETFLLEGSQG 637
                        650       660
                 ....*....|....*....|....*...
gi 490365282 636 YDVMGWTKEQIIHDILDQYEKHIHFLHV 663
Cdd:PRK09928 638 NDLMDYSKEQVINDILDQYERHLNFLHL 665
BetT COG1292
Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];
1-516 0e+00

Choline-glycine betaine transporter [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440903  Cd Length: 512  Bit Score: 703.83  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   1 MSQQNeitPKKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRF 80
Cdd:COG1292    1 MSDKN---KEKFKKKIDPPVFIPSALLILAFVLWGLLFPEAAGAVLNAAFSWITTNFGWFYLLLVLLFVVFCLYLAFSKY 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  81 GEIKLGPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTG-DAQTIEAAKEAMRLTFFHWGLHAWAIYAI 159
Cdd:COG1292   78 GKIRLGGDDAKPEFSTFSWFAMLFSAGMGIGLVFWGVAEPLYHFLSPPPGvEPGSPEAARWAMAYTFFHWGLHAWAIYAL 157
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 160 VALILAFFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVV 239
Cdd:COG1292  158 VGLALAYFAYRRGLPLTISSALYPLLGDRIYGPIGKVIDILAVFATVFGVATSLGLGALQINAGLNYLFGIPNSLTVQII 237
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 240 LIVVITGLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPksSDW 319
Cdd:COG1292  238 IIAVITALFTISAVSGLDKGIKRLSNLNMVLALLLLLFVLIVGPTLFILNLFVQSLGDYLQNFVPMSLWTDAYGD--TGW 315
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 320 LGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDkGAEVLANIVQQDVSL 399
Cdd:COG1292  316 LGGWTVFYWAWWIAWAPFVGLFIARISRGRTIREFVLGVLLVPTLFTFLWFSVFGGTAIHLELN-GGGDLAEAVAAGVEA 394
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 400 ALFEFLNYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLASGGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTV 479
Cdd:COG1292  395 ALFALLEQLPLGTILSVLAIILVIIFFVTSADSGSLVLAMLTSGGDEEPPRWQRIFWGVLIGLVAAVLLLAGGLSALQTA 474
                        490       500       510
                 ....*....|....*....|....*....|....*..
gi 490365282 480 TIASALPFAIVLLASIYGLIKALRVDVYKRDSQQMTT 516
Cdd:COG1292  475 SIITALPFSFVLLLMCVSLVKALREDPRRLRSAEAEA 511
BCCT pfam02028
BCCT, betaine/carnitine/choline family transporter;
20-505 0e+00

BCCT, betaine/carnitine/choline family transporter;


Pssm-ID: 460420  Cd Length: 485  Bit Score: 634.96  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   20 VFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKLGPDHARPHFSYFAW 99
Cdd:pfam02028   1 VFAVSAGLILAFVLLGLIFPEALSAVVNTALDWITDNFGWFYLLLVLIFLVFALFLAFSRYGNIRLGGDDDKPEFSTFSW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  100 FAMLFSAGMGIGLMFFGVAEPVMHYL-MPPTGDAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLR 178
Cdd:pfam02028  81 FAMLFAAGMGIGLVFWGVAEPLSHYLsPPPGGEPGTPEAAQQAMAYTFFHWGLHAWAIYALVALALAYFAYRKGLPLLIS 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  179 SALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVITGLATISVVSGLEK 258
Cdd:pfam02028 161 SALYPLLGDRIDGPIGKAIDILAIIATVFGVATSLGLGALQINAGLSYLFGIPNTLTTQLAIIAIITALFTISAVSGLDK 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  259 GIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYEPkSSDWLGGWTLLYWGWWLSWSPFV 338
Cdd:pfam02028 241 GIKRLSNLNMYLAVALLLFVLIAGPTLFILNTFVQSLGDYLQNFVPMSFYTDPFGD-TGGWLGGWTIFYWAWWIAWAPFV 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  339 GMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDKGAEvLANIVQQDVSLALFEFLNYFPFSSVLSFVA 418
Cdd:pfam02028 320 GMFIARISRGRTIREFILGVLLVPTLFTFLWFSVFGGTAIYLELNGPGD-LADAVEAGPPAALFALLEQLPLGTILSVLA 398
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  419 MLMVIVFFVTSADSGAMVVDTLASGGDSETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIASALPFAIVLLASIYGL 498
Cdd:pfam02028 399 LLLIIIFFVTSADSGTLVIAMLSSGGDLNPPRWQRVFWGVLLGAVAAVLLLAGGLEALQSASIIAALPFSFILLLMCISL 478

                  ....*..
gi 490365282  499 IKALRVD 505
Cdd:pfam02028 479 FKALREE 485
bcct TIGR00842
choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family ...
58-505 8.36e-170

choline/carnitine/betaine transport; The Betaine/Carnitine/Choline Transporter (BCCT) Family (TC 2.A.15) Proteins of the BCCT family share the common functional feature of transporting molecules with a quaternary ammonium group [R-N+(CH3)3]. The BCCT family includes transporters for carnitine, choline and glycine betaine. BCCT transporters have 12 putative TMS, and are energized by pmf-driven proton symport. Some of these permeases exhibit osmosensory and osmoregulatory properties inherent to their polypeptide chains. [Transport and binding proteins, Other]


Pssm-ID: 213565  Cd Length: 452  Bit Score: 493.02  E-value: 8.36e-170
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282   58 SWFYILAVALVLLSVTYLGLSRFGEIKLGPDHARPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDAQTIEA 137
Cdd:TIGR00842   1 GWAYILTVTLFLGFVLYIAFSRYGKIRLGRDDEKPEFSTLSWLAMLFAAGMGAGLMFWGVAEPLTYYLTPPFGAGPTSTT 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  138 AKE-AMRLTFFHWGLHAWAIYAIVALILAFFSYRHGLPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFG 216
Cdd:TIGR00842  81 AQEqALAYTLFHWGIHPWAIYALVGLALAYFHFRKGLPLRLSSALVPLLGEKVNGPIGKAIDILALVATVFGVATSLGLG 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  217 VLQVNAGLNHLFDIPINPTVQVVLIVVITGLATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTG 296
Cdd:TIGR00842 161 APQINAGLSALFGIPDSFWLQALIILCVTALACISVASGVGKGIKILSNINMALAFLLLLFVLIVGPTVFLLNSFVDSIG 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  297 GYLSEIVSKTFNLYAYEPKSSdWLGGWTLLYWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNT 376
Cdd:TIGR00842 241 NYLQNFPQMSFRTDPDDGKGG-WPGGWTVFYWAWWISWSPFVGMFIARISRGRTIREFIFGVLLGPTAFTWLWFSVFGNS 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  377 AIYLIKDKGAEVLANIVQQDVSLALFEFLNYFPFSSVLSFVAMLMVIVFFVTSADSGAMVVDTLASGG---DSETPVWQR 453
Cdd:TIGR00842 320 ALLLQQNGGFINGPFVVETNGARALFGLLAALPLGTITMALALILIIIFFITSADSASLVLANTTSRGgqlGEEPPKWVR 399
                         410       420       430       440       450
                  ....*....|....*....|....*....|....*....|....*....|...
gi 490365282  454 IFWAALMGISAITLLLA-GGLSALQTVTIASALPFAIVLLASIYGLIKALRVD 505
Cdd:TIGR00842 400 VFWAVAIGLIALVLLFSgGSLAALQTTTIIAALPFSFVMLVVMFSLIKDLKQD 452
PRK03356 PRK03356
L-carnitine/gamma-butyrobetaine antiport BCCT transporter;
10-504 2.42e-59

L-carnitine/gamma-butyrobetaine antiport BCCT transporter;


Pssm-ID: 179568  Cd Length: 504  Bit Score: 207.66  E-value: 2.42e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  10 KKIRMKINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKLGPDh 89
Cdd:PRK03356   4 EKKKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVFSYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGDE- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  90 aRPHFSYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTG-DAQTIEAAKEAMRLTFFHWGLHAWAIYAIVALILAFFS 168
Cdd:PRK03356  83 -KPEFSTASWIFMMFASCTSAAVLFWGSIEIYYYISTPPFGlEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFGYFF 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 169 YRHGLPLTLRS-ALYPIIGDR-IYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVITG 246
Cdd:PRK03356 162 FVRKMDVIRPSsTLVPLVGEKhAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTECMQWLFGIPHTLQLDAIIITCWII 241
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 247 LATISVVSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSKTFNLYAYepKSSDWLGGWTLL 326
Cdd:PRK03356 242 LNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIVGGTSFIMNYFTDSVGMLLMYLPRMLFYTDPI--GKGGFPQGWTVF 319
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 327 YWGWWLSWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDKGAEVLANIVQQDVSLALFEFLN 406
Cdd:PRK03356 320 YWAWWVIYAIQMSIFLARISRGRTVRELCFGMVLGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVARAIIETWA 399
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 407 YFPFSSVLSFVAMLMVIVFFVTSADSG----AMVVDTLASGGDsETPVWQRIFWAALMGISAITLLLAGGLSALQTVTIA 482
Cdd:PRK03356 400 ALPLSTATMWGFFILCFIATVTLINACsytlAMSTCREVRDGE-EPPLLVRIGWSILVGIIGIVLLALGGLKPIQTAIIA 478
                        490       500
                 ....*....|....*....|..
gi 490365282 483 SALPFAIVLLASIYGLIKALRV 504
Cdd:PRK03356 479 GGCPLFFVNIMVTLSFIKDAKQ 500
PRK09950 PRK09950
putative transporter; Provisional
15-505 6.41e-56

putative transporter; Provisional


Pssm-ID: 236636  Cd Length: 506  Bit Score: 198.47  E-value: 6.41e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  15 KINPPVFYTSAILIMLVVGFSALFPELANDKLGHLQENLFTNASWFYILAVALVLLSVTYLGLSRFGEIKLGpdHARPHF 94
Cdd:PRK09950   7 KKDKPLISTSLLAVFFIVAALSLFPQQSAAAANTIFQWVTRTFGSPVQLFVLLAMILVLYLATSKYGNIRLG--EGKPEY 84
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282  95 SYFAWFAMLFSAGMGIGLMFFGVAEPVMHYLMPPTGDA-QTIEAAKEAMRLTFFHWGLHAWAIYAIVALILAF-FSYRHG 172
Cdd:PRK09950  85 STLSWLFMFICAGLGSSTLYWGVMEWAYYYQTPGLNIApRSPKALEYSVSYSFFHWGISAWATYALASLIMAYhFHVRKN 164
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 173 LPLTLRSALYPIIGDRIYGPIGHAVDIFAVMGTVFGVATSLGFGVLQVNAGLNHLFDIPINPTVQVVLIVVITGLATISV 252
Cdd:PRK09950 165 KGLSLSGIIAAITGVKPQGPWGRLVDLMFLIATVGALTISLVVTAATFTRGLSALTGLPNNFTVQAFVILLSGVIFCLSS 244
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 253 VSGLEKGIRFLSELNLGLAVILLLLVIILGPTVLILKSFVENTGGYLSEIVSktFNLYAYEPKSSDWLGGWTLLYWGWWL 332
Cdd:PRK09950 245 YIGIDNGLQRLSKMVGWGAFLFALLVLIVGPTEFITNNIINSIGLTTQNFLQ--MSLFTDPMGDGSFTRNWTVFYWLWWI 322
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 333 SWSPFVGMFIARISRGRTIREFVVGVLFVPAGFTLLWMTVFGNTAIYLIKDKGAEVLANIVQQDVSLALFEFLNYFPFSS 412
Cdd:PRK09950 323 SYTPGVAMFVTRVSRGRKIKEVIWGLILGSSVGCWFFFGVLESYAIHQFINGVINVPQILNTLGGETAVQQLLSSLPAGK 402
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490365282 413 VLSFVAMLMVIVFFVTSADSGAMVVDTLA----SGGDSETPVwQRIFWAALMGISAITLLLAGGLS-ALQTVTIASALPF 487
Cdd:PRK09950 403 LFLAAYLGIMIIFLASHMDAVAYTMAATStrnlREGDDPDRG-LRLFWCVVITLIPLSILFTGASLdTMKTTVVLTALPF 481
                        490
                 ....*....|....*...
gi 490365282 488 AIVLLASIYGLIKALRVD 505
Cdd:PRK09950 482 LVILLIKVYGFIRWLKQD 499
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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