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Conserved domains on  [gi|490366213|ref|WP_004245877|]
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MULTISPECIES: aromatic amino acid DMT transporter YddG [Proteus]

Protein Classification

drug/metabolite transporter permease( domain architecture ID 11485459)

drug/metabolite transporter (DMT) permease is an inner membrane protein involved in the transport of one or more of a variety of substrates such as amino acids, drugs, metabolites, and sugar phosphates, among others; similar to Escherichia coli methyl viologen resistance protein YddG

PubMed:  17784858|27281193

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK11689 PRK11689
aromatic amino acid efflux DMT transporter YddG;
4-298 4.49e-139

aromatic amino acid efflux DMT transporter YddG;


:

Pssm-ID: 183277 [Multi-domain]  Cd Length: 295  Bit Score: 394.62  E-value: 4.49e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213   4 STSKGTLYGIVAIFLWSTIVGLIRNISEYFGAVGGAALIYTTGTLFLILILGVPKLSLFPKRYLAWGALLFVSYEICLSL 83
Cdd:PRK11689   1 TSQKATLIGLIAILLWSTMVGLIRGVSESLGPVGGAAMIYSVSGLLLLLTVGFPRLRQFPKRYLLAGGLLFVSYEICLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213  84 ALGFASDRAQAIELGMVNYLWPSFTLALAVFLNKQRFSILLIVGLLCSFSGLVWVVSGDNPLTIESLWNNICRNPLSYIL 163
Cdd:PRK11689  81 SLGYANTRRQAIEVGMVNYLWPSLTILFAVLFNGQKANWLLIPGLLLALAGVAWVLGGDNGLSLAELINNIASNPLSYGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213 164 AFIGAVLWAFYSNVTRLISGGHNGIVPFFFLTALALWGQYIFSAPIEWVVNVKSISLLLITGAAIGLANAAWTAGMISGN 243
Cdd:PRK11689 161 AFIGAFIWAAYCNVTRKYARGKNGITLFFILTALALWIKYFLSPQPAMVFSLPAIIKLLLAAAAMGFGYAAWNVGILHGN 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490366213 244 VTLLATLSYFTPVISTAFSSLLLSTALSFSFWQGVMMVTGGSLICWLATRQKMTK 298
Cdd:PRK11689 241 MTLLATASYFTPVLSAALAALLLSTPLSFSFWQGVAMVTAGSLLCWLATRRKRRT 295
 
Name Accession Description Interval E-value
PRK11689 PRK11689
aromatic amino acid efflux DMT transporter YddG;
4-298 4.49e-139

aromatic amino acid efflux DMT transporter YddG;


Pssm-ID: 183277 [Multi-domain]  Cd Length: 295  Bit Score: 394.62  E-value: 4.49e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213   4 STSKGTLYGIVAIFLWSTIVGLIRNISEYFGAVGGAALIYTTGTLFLILILGVPKLSLFPKRYLAWGALLFVSYEICLSL 83
Cdd:PRK11689   1 TSQKATLIGLIAILLWSTMVGLIRGVSESLGPVGGAAMIYSVSGLLLLLTVGFPRLRQFPKRYLLAGGLLFVSYEICLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213  84 ALGFASDRAQAIELGMVNYLWPSFTLALAVFLNKQRFSILLIVGLLCSFSGLVWVVSGDNPLTIESLWNNICRNPLSYIL 163
Cdd:PRK11689  81 SLGYANTRRQAIEVGMVNYLWPSLTILFAVLFNGQKANWLLIPGLLLALAGVAWVLGGDNGLSLAELINNIASNPLSYGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213 164 AFIGAVLWAFYSNVTRLISGGHNGIVPFFFLTALALWGQYIFSAPIEWVVNVKSISLLLITGAAIGLANAAWTAGMISGN 243
Cdd:PRK11689 161 AFIGAFIWAAYCNVTRKYARGKNGITLFFILTALALWIKYFLSPQPAMVFSLPAIIKLLLAAAAMGFGYAAWNVGILHGN 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490366213 244 VTLLATLSYFTPVISTAFSSLLLSTALSFSFWQGVMMVTGGSLICWLATRQKMTK 298
Cdd:PRK11689 241 MTLLATASYFTPVLSAALAALLLSTPLSFSFWQGVAMVTAGSLLCWLATRRKRRT 295
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 5-295 1.02e-19

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 87.20  E-value: 1.02e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213   5 TSKGTLYGIVAIFLWSTIVGLIRNISEYFGAVGGAALIYTTGTLFLILILGVPKLSLFPKRYLAWGALLFVS-YEICLSL 83
Cdd:COG0697    1 RLRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGlLGLALAF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213  84 ALGFAS-DRAQAIELGMVNYLWPSFTLALAVFLNKQRFSILLIVGLLCSFSGLVWVVSGDNPLTIESLWnnicrnplSYI 162
Cdd:COG0697   81 LLFFLAlQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLL--------GDL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213 163 LAFIGAVLWAFYSNVTRLISGGHNGIVPFFFLTALALWGQYIFSAPIEWVVNVKSISLLLITGAAI---GLANAAWTAGM 239
Cdd:COG0697  153 LALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLPLPLSAAAWLALLYLGLfgtALAYLLWFRAL 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490366213 240 ISGNVTLLATLSYFTPVISTAFSSLLLSTALSFSFWQGVMMVTGGSLICWLATRQK 295
Cdd:COG0697  233 RRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRERRR 288
 
Name Accession Description Interval E-value
PRK11689 PRK11689
aromatic amino acid efflux DMT transporter YddG;
4-298 4.49e-139

aromatic amino acid efflux DMT transporter YddG;


Pssm-ID: 183277 [Multi-domain]  Cd Length: 295  Bit Score: 394.62  E-value: 4.49e-139
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213   4 STSKGTLYGIVAIFLWSTIVGLIRNISEYFGAVGGAALIYTTGTLFLILILGVPKLSLFPKRYLAWGALLFVSYEICLSL 83
Cdd:PRK11689   1 TSQKATLIGLIAILLWSTMVGLIRGVSESLGPVGGAAMIYSVSGLLLLLTVGFPRLRQFPKRYLLAGGLLFVSYEICLAL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213  84 ALGFASDRAQAIELGMVNYLWPSFTLALAVFLNKQRFSILLIVGLLCSFSGLVWVVSGDNPLTIESLWNNICRNPLSYIL 163
Cdd:PRK11689  81 SLGYANTRRQAIEVGMVNYLWPSLTILFAVLFNGQKANWLLIPGLLLALAGVAWVLGGDNGLSLAELINNIASNPLSYGL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213 164 AFIGAVLWAFYSNVTRLISGGHNGIVPFFFLTALALWGQYIFSAPIEWVVNVKSISLLLITGAAIGLANAAWTAGMISGN 243
Cdd:PRK11689 161 AFIGAFIWAAYCNVTRKYARGKNGITLFFILTALALWIKYFLSPQPAMVFSLPAIIKLLLAAAAMGFGYAAWNVGILHGN 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 490366213 244 VTLLATLSYFTPVISTAFSSLLLSTALSFSFWQGVMMVTGGSLICWLATRQKMTK 298
Cdd:PRK11689 241 MTLLATASYFTPVLSAALAALLLSTPLSFSFWQGVAMVTAGSLLCWLATRRKRRT 295
RhaT COG0697
Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and ...
 5-295 1.02e-19

Permease of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism, Amino acid transport and metabolism, General function prediction only];


Pssm-ID: 440461 [Multi-domain]  Cd Length: 290  Bit Score: 87.20  E-value: 1.02e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213   5 TSKGTLYGIVAIFLWSTIVGLIRNISEYFGAVGGAALIYTTGTLFLILILGVPKLSLFPKRYLAWGALLFVS-YEICLSL 83
Cdd:COG0697    1 RLRGILLLLLAALLWGSSFVAIKLALAGLPPLQLAFLRFLLAALLLLPLLLLRGRRLPPLSRRDWLLLLLRGlLGLALAF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213  84 ALGFAS-DRAQAIELGMVNYLWPSFTLALAVFLNKQRFSILLIVGLLCSFSGLVWVVSGDNPLTIESLWnnicrnplSYI 162
Cdd:COG0697   81 LLFFLAlQYTPAALAALLLALAPLFVALLAALLLGERLSRRRWLGLLLGFAGVLLIVGPGGGGGGGSLL--------GDL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490366213 163 LAFIGAVLWAFYSNVTRLISGGHNGIVPFFFLTALALWGQYIFSAPIEWVVNVKSISLLLITGAAI---GLANAAWTAGM 239
Cdd:COG0697  153 LALLAALSWALYTVLTRRLSRRLDPLTLTFWQMLVGALLLLPLALLTGLPLPLSAAAWLALLYLGLfgtALAYLLWFRAL 232

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490366213 240 ISGNVTLLATLSYFTPVISTAFSSLLLSTALSFSFWQGVMMVTGGSLICWLATRQK 295
Cdd:COG0697  233 RRLGASRAAPLTYLEPVFAVLLGWLLLGEPLTPLQLLGAALILAGVLLAALRERRR 288
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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