|
Name |
Accession |
Description |
Interval |
E-value |
| tpiA |
PRK00042 |
triosephosphate isomerase; Provisional |
2-246 |
1.53e-138 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 234589 Cd Length: 250 Bit Score: 389.48 E-value: 1.53e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 2 RHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSPE 81
Cdd:PRK00042 1 RKPIIAGNWKMNKTLAEAKALVEELKAALPDADGVEVAVAPPFTALASVKEALKGSNIKLGAQNVHPEDSGAFTGEISAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 82 MLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFKD 161
Cdd:PRK00042 81 MLKDLGVKYVIIGHSERRQYFGETDELVNKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLEAALAGLSAEQFAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 162 AVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADA 241
Cdd:PRK00042 161 LVIAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYGEVAEKVRILYGGSVKPDNAAELMAQPDIDGALVGGASLKAED 240
|
....*
gi 490370095 242 FAVIV 246
Cdd:PRK00042 241 FLAIV 245
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
1-246 |
7.56e-138 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 387.49 E-value: 7.56e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 1 MRHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSP 80
Cdd:COG0149 1 MRKPLIAGNWKMNGTLAEAKALLAALAAALADLADVEVVVCPPFTYLAAVAEALAGSPIALGAQNVHWEDSGAYTGEISA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 81 EMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFK 160
Cdd:COG0149 81 AMLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLSAEQAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 161 DAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQ-DAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKA 239
Cdd:COG0149 161 NVVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELyGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDA 240
|
....*..
gi 490370095 240 DAFAVIV 246
Cdd:COG0149 241 EDFLAIV 247
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
4-246 |
4.38e-126 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 357.62 E-value: 4.38e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 4 PLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVLKDESGVEVVVAPPFTYLAAVAEALEGSKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNahGAQAFKDAV 163
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLA--GVEDLAPVV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFA 243
Cdd:cd00311 159 IAYEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGEVAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAESFL 238
|
...
gi 490370095 244 VIV 246
Cdd:cd00311 239 DII 241
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
4-246 |
2.03e-125 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 356.05 E-value: 2.03e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 4 PLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARhEIGGSRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADESGVEVVVAPPFTYLSAVA-ELLGSNIKVGAQNVDPEESGAFTGEISAEML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAfKDAV 163
Cdd:pfam00121 80 KDLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEQ-KNLV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFA 243
Cdd:pfam00121 159 IAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEDFL 238
|
...
gi 490370095 244 VIV 246
Cdd:pfam00121 239 DII 241
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
5-240 |
2.16e-74 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 225.07 E-value: 2.16e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 5 LVMGNWK-LNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIggsRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:TIGR00419 1 LVIGNWKtYNESRGMRALEVAKIAEEVASEAGVAVAVAPPFVDLPMIKREV---EIPVYAQHVDAVLSGAHTGEISAEML 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRtyHKESDefIAQKFGVLKELGLTPVLCIgeteaeneagktqevcarqiDAILNAHGAQAFKDAV 163
Cdd:TIGR00419 78 KDIGAKGTLINHSERR--MKLAD--IEKKIARLKELGLTSVVCT--------------------NNVLTTAAAAALEPDV 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRdhiakQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKAD 240
Cdd:TIGR00419 134 VAVEPPELIGTGIPVSPAQPEVVHGSVR-----AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| tpiA |
PRK00042 |
triosephosphate isomerase; Provisional |
2-246 |
1.53e-138 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 234589 Cd Length: 250 Bit Score: 389.48 E-value: 1.53e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 2 RHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSPE 81
Cdd:PRK00042 1 RKPIIAGNWKMNKTLAEAKALVEELKAALPDADGVEVAVAPPFTALASVKEALKGSNIKLGAQNVHPEDSGAFTGEISAE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 82 MLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFKD 161
Cdd:PRK00042 81 MLKDLGVKYVIIGHSERRQYFGETDELVNKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLEAALAGLSAEQFAN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 162 AVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADA 241
Cdd:PRK00042 161 LVIAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYGEVAEKVRILYGGSVKPDNAAELMAQPDIDGALVGGASLKAED 240
|
....*
gi 490370095 242 FAVIV 246
Cdd:PRK00042 241 FLAIV 245
|
|
| TpiA |
COG0149 |
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase ... |
1-246 |
7.56e-138 |
|
Triosephosphate isomerase [Carbohydrate transport and metabolism]; Triosephosphate isomerase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439919 [Multi-domain] Cd Length: 249 Bit Score: 387.49 E-value: 7.56e-138
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 1 MRHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSP 80
Cdd:COG0149 1 MRKPLIAGNWKMNGTLAEAKALLAALAAALADLADVEVVVCPPFTYLAAVAEALAGSPIALGAQNVHWEDSGAYTGEISA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 81 EMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFK 160
Cdd:COG0149 81 AMLKDLGCRYVIVGHSERRQYFGETDELVNKKVKAALAAGLTPILCVGETLEEREAGKTEEVVARQLKAALAGLSAEQAA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 161 DAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQ-DAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKA 239
Cdd:COG0149 161 NVVIAYEPVWAIGTGKTATPEQAQEVHAFIRALLAELyGAEVAEAVRILYGGSVKPGNAAELFAQPDIDGALVGGASLDA 240
|
....*..
gi 490370095 240 DAFAVIV 246
Cdd:COG0149 241 EDFLAIV 247
|
|
| TIM |
cd00311 |
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of ... |
4-246 |
4.38e-126 |
|
Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually homodimeric, but in some organisms tetrameric, is ubiqitous and conserved in function across eukaryotes, bacteria and archaea.
Pssm-ID: 238190 Cd Length: 242 Bit Score: 357.62 E-value: 4.38e-126
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 4 PLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:cd00311 1 PLVAGNWKMNGTLAEALELAKALNAVLKDESGVEVVVAPPFTYLAAVAEALEGSKIKVGAQNVSPEDSGAFTGEISAEML 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNahGAQAFKDAV 163
Cdd:cd00311 81 KDAGAKYVIIGHSERRQYFGETDEDVAKKVKAALEAGLTPILCVGETLEEREAGKTEEVVAAQLAAVLA--GVEDLAPVV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFA 243
Cdd:cd00311 159 IAYEPVWAIGTGKTASPEQAQEVHAFIRKLLAELYGEVAEKVRILYGGSVNPENAAELLAQPDIDGVLVGGASLKAESFL 238
|
...
gi 490370095 244 VIV 246
Cdd:cd00311 239 DII 241
|
|
| TIM |
pfam00121 |
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic ... |
4-246 |
2.03e-125 |
|
Triosephosphate isomerase; Triosephosphate isomerase (EC:5.3.1.1) (TIM) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. TIM plays an important role in several metabolic pathways and is essential for efficient energy production, present in eukaryotes and prokaryotes. TIM is a dimer of identical subunits, each of which is made up of about 250 amino-acid residues. A glutamic acid residue is involved in the catalytic mechanism. The tertiary structure of TIM has eight beta/alpha motifs folded into a barrel structure. The sequence around the active site residue is perfectly conserved in all known TIM's. Deficiencies in TIM are associated with haemolytic anaemia coupled with a progressive, severe neurological disorder.
Pssm-ID: 459680 Cd Length: 244 Bit Score: 356.05 E-value: 2.03e-125
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 4 PLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARhEIGGSRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:pfam00121 1 PIIAGNWKMNGTLAEAAELLAELAEALADESGVEVVVAPPFTYLSAVA-ELLGSNIKVGAQNVDPEESGAFTGEISAEML 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAfKDAV 163
Cdd:pfam00121 80 KDLGVSYVIIGHSERRQYFGETDEDVAKKVKAALKAGLTPILCVGETLEEREAGKTEEVVARQLDAALAGLGAEQ-KNLV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFA 243
Cdd:pfam00121 159 IAYEPVWAIGTGKTATPEQAQEVHAFIRAVLAELYKEVAEGVRILYGGSVKPGNAAELAAQPDIDGALVGGASLKAEDFL 238
|
...
gi 490370095 244 VIV 246
Cdd:pfam00121 239 DII 241
|
|
| PTZ00333 |
PTZ00333 |
triosephosphate isomerase; Provisional |
1-246 |
9.93e-99 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 240365 Cd Length: 255 Bit Score: 288.74 E-value: 9.93e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 1 MRHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSP 80
Cdd:PTZ00333 3 KRKPFVGGNWKCNGTKASIKELIDSFNKLKFDPNNVDVVVAPPSLHIPLVQEKLKNKNFKISSQNVSLTGSGAFTGEISA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 81 EMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFK 160
Cdd:PTZ00333 83 EMLKDLGINWTILGHSERRQYFGETNEIVAQKVKNALENGLKVILCIGETLEEREAGQTSDVLSKQLEAIVKKVSDEAWD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 161 DAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQ-DAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKA 239
Cdd:PTZ00333 163 NIVIAYEPVWAIGTGKVATPEQAQEVHAFIRKWLAEKvGADVAEATRIIYGGSVNEKNCKELIKQPDIDGFLVGGASLKP 242
|
....*..
gi 490370095 240 DaFAVIV 246
Cdd:PTZ00333 243 D-FVDII 248
|
|
| PRK13962 |
PRK13962 |
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional |
1-246 |
3.19e-90 |
|
bifunctional phosphoglycerate kinase/triosephosphate isomerase; Provisional
Pssm-ID: 237572 [Multi-domain] Cd Length: 645 Bit Score: 279.30 E-value: 3.19e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 1 MRHPLVMGNWKLNGSIHMVHELIAALRKEISGVAGcDVAIAPPTVYLCQARHEIGGSRIALGAQDTGVNLSGAFTGETSP 80
Cdd:PRK13962 396 PRKPIIAGNWKMNKTPAEAKEFVNELKKYVKDAQA-EVVVCPPFTALPSVKEAVDGSNIKLGAQNVFYEEKGAYTGEISG 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 81 EMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGAQAFK 160
Cdd:PRK13962 475 PMLAEIGVEYVIIGHSERRQYFGETDELVNKKVLAALKAGLTPILCVGETLDERESGITFDVVRLQLKAALNGLSAEQVK 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 161 DAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIA-KQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKA 239
Cdd:PRK13962 555 KVVIAYEPVWAIGTGKVATPEQAQEVHAFIRKLVAeLYGEEAARKVRILYGGSVKSENAAGLFNQPDIDGGLVGGASLKA 634
|
....*..
gi 490370095 240 DAFAVIV 246
Cdd:PRK13962 635 QEFAAIA 641
|
|
| tim |
TIGR00419 |
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that ... |
5-240 |
2.16e-74 |
|
triosephosphate isomerase; Triosephosphate isomerase (tim/TPIA) is the glycolytic enzyme that catalyzes the reversible interconversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. The active site of the enzyme is located between residues 240-258 of the model ([AV]-Y-E-P-[LIVM]-W-[SA]-I-G-T-[GK]) with E being the active site residue. There is a slight deviation from this sequence within the archeal members of this family. [Energy metabolism, Glycolysis/gluconeogenesis]
Pssm-ID: 129513 [Multi-domain] Cd Length: 205 Bit Score: 225.07 E-value: 2.16e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 5 LVMGNWK-LNGSIHMVHELIAALRKEISGVAGCDVAIAPPTVYLCQARHEIggsRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:TIGR00419 1 LVIGNWKtYNESRGMRALEVAKIAEEVASEAGVAVAVAPPFVDLPMIKREV---EIPVYAQHVDAVLSGAHTGEISAEML 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRtyHKESDefIAQKFGVLKELGLTPVLCIgeteaeneagktqevcarqiDAILNAHGAQAFKDAV 163
Cdd:TIGR00419 78 KDIGAKGTLINHSERR--MKLAD--IEKKIARLKELGLTSVVCT--------------------NNVLTTAAAAALEPDV 133
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRdhiakQDAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKAD 240
Cdd:TIGR00419 134 VAVEPPELIGTGIPVSPAQPEVVHGSVR-----AVKEVNESVRVLCGAGISTGEDAELAAQLGAEGVLLASGSLKAD 205
|
|
| PLN02561 |
PLN02561 |
triosephosphate isomerase |
2-245 |
3.05e-68 |
|
triosephosphate isomerase
Pssm-ID: 178175 Cd Length: 253 Bit Score: 211.22 E-value: 3.05e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 2 RHPLVMGNWKLNGSIHMVHELIAALRK-EISGVAGCDVAIAPPTVYLCQARHEIGgSRIALGAQDTGVNLSGAFTGETSP 80
Cdd:PLN02561 3 RKFFVGGNWKCNGTVEEVKKIVTTLNEaEVPSEDVVEVVVSPPFVFLPLVKSLLR-PDFQVAAQNCWVKKGGAFTGEISA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 81 EMLKNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAIlnAHGAQAFK 160
Cdd:PLN02561 82 EMLVNLGIPWVILGHSERRALLGESNEFVGDKVAYALSQGLKVIACVGETLEQRESGSTMDVVAAQTKAI--ADKVSDWA 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 161 DAVIAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQ-DAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKA 239
Cdd:PLN02561 160 NVVLAYEPVWAIGTGKVATPAQAQEVHDELRKWLHKNvSPEVAATTRIIYGGSVTGANCKELAAQPDVDGFLVGGASLKP 239
|
....*.
gi 490370095 240 DAFAVI 245
Cdd:PLN02561 240 EFIDII 245
|
|
| PLN02429 |
PLN02429 |
triosephosphate isomerase |
13-246 |
1.28e-55 |
|
triosephosphate isomerase
Pssm-ID: 166070 Cd Length: 315 Bit Score: 181.14 E-value: 1.28e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 13 NGSIHMVHELIAALRKEiSGVAGCDVAIAPPTVYLCQARHEIGgSRIALGAQDTGVNLSGAFTGETSPEMLKNVDVKYVI 92
Cdd:PLN02429 75 NGTKDSIAKLISDLNSA-TLEADVDVVVSPPFVYIDQVKSSLT-DRIDISGQNSWVGKGGAFTGEISVEQLKDLGCKWVI 152
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 93 IGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAhgAQAFKDAVIAYEPIWAI 172
Cdd:PLN02429 153 LGHSERRHVIGEKDEFIGKKAAYALSEGLGVIACIGEKLEEREAGKTFDVCFAQLKAFADA--VPSWDNIVVAYEPVWAI 230
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490370095 173 GTGKSATPAQAQAVHKFIRDHIAKQ-DAAIAEQVIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFAVIV 246
Cdd:PLN02429 231 GTGKVASPQQAQEVHVAVRGWLKKNvSEEVASKTRIIYGGSVNGGNSAELAKEEDIDGFLVGGASLKGPEFATIV 305
|
|
| PRK14565 |
PRK14565 |
triosephosphate isomerase; Provisional |
5-246 |
1.16e-51 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 237758 Cd Length: 237 Bit Score: 168.40 E-value: 1.16e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 5 LVMGNWKLNGSIHMVHELIAALR-KEISGVAGCDVAIAPPTVyLCQARHEiGGSRIALGAQDTGVNLSGAFTGETSPEML 83
Cdd:PRK14565 4 LIVANWKMNGDFSLFSSFLKELSnKLANNEITLKLVICPPFT-AMSSFVE-CNPNIKLGAQNCFYGSSGGYTGEISAKML 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 84 KNVDVKYVIIGHSERRTYHKESDEFIAQKFGVLKELGLTPVLCIGETEAENEAGKTQEVCARQIDAILNAHGaqafkDAV 163
Cdd:PRK14565 82 KECGCSYVILGHSERRSTFHETDSDIRLKAESAIESGLIPIICVGETLEDRENGMTKDVLLEQCSNCLPKHG-----EFI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 164 IAYEPIWAIGTGKSATPAQAQAVHKFIRDHIAKQDaaiaeqviIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFA 243
Cdd:PRK14565 157 IAYEPVWAIGGSTIPSNDAIAEAFEIIRSYDSKSH--------IIYGGSVNQENIRDLKSINQLSGVLVGSASLDVDSFC 228
|
...
gi 490370095 244 VIV 246
Cdd:PRK14565 229 KII 231
|
|
| PRK14905 |
PRK14905 |
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; ... |
50-246 |
2.68e-38 |
|
triosephosphate isomerase/PTS system glucose/sucrose-specific transporter subunit IIB; Provisional
Pssm-ID: 184898 [Multi-domain] Cd Length: 355 Bit Score: 137.09 E-value: 2.68e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 50 ARHEIGGSRIALGAQDTGVNLSGAFTGETSPEMLKNVDVKYVIIGHSERRTYHKESDEFIAQKfgVLKEL--GLTPVLCI 127
Cdd:PRK14905 58 AASETGHPKIKIGAQNMNAKDKGQFTGEISPLMLKELGIELVMIGHSERRHVLKETDQEENEK--VLAALkhGFITLLCI 135
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 128 GETEAENEAGKTQEVCARQIDAILNAHGAQAFKDAVIAYEPIWAIGTGksATPAQAQAV---HKFIRDHIAKQDAAIAEQ 204
Cdd:PRK14905 136 GETLEQKNYNISDEVLRTQLKIGLHGVSAEQLPHLFIAYEPVWAIGEG--GIPASAEYAdekHAIIKQCLFELFAEESKK 213
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 490370095 205 VIIQYGGSVNDKNAAELFSQPDIDGALVGGASLKADAFAVIV 246
Cdd:PRK14905 214 IPVLYGGSVNLENANELIMKPHIDGLFIGRSAWDAQCFHALI 255
|
|
| PRK15492 |
PRK15492 |
triosephosphate isomerase; Provisional |
59-246 |
6.62e-36 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 185389 Cd Length: 260 Bit Score: 128.19 E-value: 6.62e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 59 IALGAQDTGVNLSGAFTGETSPEMLKNVDVKYVIIGHSERRTYHKESDEFIAQKfgVLKEL--GLTPVLCIGETEAENEA 136
Cdd:PRK15492 66 IIIGAQNMNPNDNGQFTGDISPLMLKEIGTQLVMIGHSERRHKFGETDQEENAK--VLAALkhDFTTLLCVGETLEQKNY 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 137 GKTQEVCARQIDAILNAHGAQAFKDAVIAYEPIWAIGT-GKSATPAQAQAVHKFIRDHIAKQDAAIAEQVIIQYGGSVND 215
Cdd:PRK15492 144 GISDEILRTQLKIGLHGINPDQLAKLRIAYEPVWAIGEaGIPASADYADEKHAVIKQCLIELFGDAGDDIPVFYGGSVNA 223
|
170 180 190
....*....|....*....|....*....|.
gi 490370095 216 KNAAELFSQPDIDGALVGGASLKADAFAVIV 246
Cdd:PRK15492 224 ENANELFGQPHIDGLFIGRSAWDADKFFAII 254
|
|
| PRK04302 |
PRK04302 |
triosephosphate isomerase; Provisional |
23-191 |
1.89e-07 |
|
triosephosphate isomerase; Provisional
Pssm-ID: 235274 Cd Length: 223 Bit Score: 50.25 E-value: 1.89e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 23 IAALRKEISGVAGCDVAIAPPTVYLCQARHEIGgsrIALGAQDTGVNLSGAFTGETSPEMLKNVDVKYVIIGHSERRTyh 102
Cdd:PRK04302 24 IAKAAEKVSKETGVRIAVAPQALDIRRVAEEVD---IPVYAQHVDPVEPGSHTGHILPEAVKDAGAVGTLINHSERRL-- 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490370095 103 KESDefIAQKFGVLKELGLTPVLCigeteAENeagktqevcarqidaILNAHGAQAFKDAVIAYEPIWAIGTGKSATPAQ 182
Cdd:PRK04302 99 TLAD--IEAVVERAKKLGLESVVC-----VNN---------------PETSAAAAALGPDYVAVEPPELIGTGIPVSKAK 156
|
....*....
gi 490370095 183 AQAVHKFIR 191
Cdd:PRK04302 157 PEVVEDAVE 165
|
|
| |
