NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|490380420|ref|WP_004259939|]
View 

MULTISPECIES: LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase [Providencia]

Protein Classification

lysophospholipid acyltransferase family protein( domain architecture ID 106732)

lysophospholipid acyltransferase (LPLAT) family protein may act as an acyltransferase of a de novo or remodeling pathway of glycerophospholipid biosynthesis, catalyzing the incorporation of an acyl group from either acyl-CoAs or acyl-acyl carrier proteins (acyl-ACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
LPLAT super family cl17185
Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; ...
 1-306 7.97e-159

Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Lysophospholipid acyltransferase (LPLAT) superfamily members are acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis. These proteins catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this superfamily are LPLATs such as glycerol-3-phosphate 1-acyltransferase (GPAT, PlsB), 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), lysophosphatidylcholine acyltransferase 1 (LPCAT-1), lysophosphatidylethanolamine acyltransferase (LPEAT, also known as, MBOAT2, membrane-bound O-acyltransferase domain-containing protein 2), lipid A biosynthesis lauroyl/myristoyl acyltransferase, 2-acylglycerol O-acyltransferase (MGAT), dihydroxyacetone phosphate acyltransferase (DHAPAT, also known as 1 glycerol-3-phosphate O-acyltransferase 1) and Tafazzin (the protein product of the Barth syndrome (TAZ) gene).


The actual alignment was detected with superfamily member PRK08025:

Pssm-ID: 473073  Cd Length: 305  Bit Score: 444.95  E-value: 7.97e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   1 MYAKNPFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVN 80
Cdd:PRK08025   1 MFPQQKFSREFLHPRYWLTWFGLGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  81 DNLKSLGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKA 160
Cdd:PRK08025  81 ENFRSLGMALLETGMAWFWPDSRVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNKL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 161 MEYIQTKGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVT 240
Cdd:PRK08025 161 MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVT 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490380420 241 LLRNKSGANYDLVLGKEILEYPsSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK08025 241 MVRKADYSGYRLFITPEMEGYP-TDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 305
 
Name Accession Description Interval E-value
PRK08025 PRK08025
kdo(2)-lipid IV(A) palmitoleoyltransferase;
1-306 7.97e-159

kdo(2)-lipid IV(A) palmitoleoyltransferase;


Pssm-ID: 181200  Cd Length: 305  Bit Score: 444.95  E-value: 7.97e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   1 MYAKNPFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVN 80
Cdd:PRK08025   1 MFPQQKFSREFLHPRYWLTWFGLGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  81 DNLKSLGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKA 160
Cdd:PRK08025  81 ENFRSLGMALLETGMAWFWPDSRVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNKL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 161 MEYIQTKGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVT 240
Cdd:PRK08025 161 MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVT 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490380420 241 LLRNKSGANYDLVLGKEILEYPsSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK08025 241 MVRKADYSGYRLFITPEMEGYP-TDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 305
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 7-306 1.99e-147

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 415.97  E-value: 1.99e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420    7 FSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSL 86
Cdd:TIGR02207   3 FSASLLHPRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFEST 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   87 GIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQT 166
Cdd:TIGR02207  83 GMALFETGMAWFWSDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWIQT 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  167 KGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVTLLRNKS 246
Cdd:TIGR02207 163 RGRLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAVPDAATTTGTSILARLSKCAVVPFTPRRNED 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490380420  247 GANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRP-EGEVSLY 306
Cdd:TIGR02207 243 GSGYRLKIDPPLDDFPGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPdEGESSLY 303
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 25-295 1.64e-102

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 300.95  E-value: 1.64e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  25 ILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWFWSDKKV 104
Cdd:COG1560    1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 105 KKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLC-FPVNAMYRPHNNKAMEYIQTKGRCRSGKGMIDRKN-L 182
Cdd:COG1560   81 RKRVEVEGLEHLEAALAEGRGVILLTPHFGNWELAGAALALRgYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDgV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 183 KFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRNKSGANYDLVLGKEIlEYP 262
Cdd:COG1560  161 RALLRALRKGGIVGLLPDQDPGRKSGVFVPFFGVP-AATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPL-EDF 238

                        250       260       270
                 ....*....|....*....|....*....|...
gi 490380420 263 SSDALQDATIINSILEVEIMKAPEQYLWAHRRF 295
Cdd:COG1560  239 SEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
6-297 7.25e-88

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 264.59  E-value: 7.25e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420    6 PFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKS 85
Cdd:pfam03279   2 KFSPELLHPRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFAS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   86 LGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFP-VNAMYRPHNNKAMEYI 164
Cdd:pfam03279  82 VGRAIVETGRVWFWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPgMAVYRPNLKNPLLDWL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  165 QTKGRCRSGKGMIDRKN-LKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSkGTSILAQLSKSPTLTVTLLR 243
Cdd:pfam03279 162 QTSGRERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGVPAATTT-GPAKLALKTKAAVIPVFPIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 490380420  244 NKSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKT 297
Cdd:pfam03279 241 NGDGSGYTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 105-296 1.04e-62

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 196.67  E-value: 1.04e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 105 KKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLC-FPVNAMYRPHNNKAMEYIQTKGRCRSGKGMIDRKN-L 182
Cdd:cd07984    1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALLgYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRGGgL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 183 KFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRNKsGANYDLVLGKEILEYP 262
Cdd:cd07984   81 RELIRALKKGEIVGILPDQDPGRKGGVFVPFFGRP-AATPTGPARLALKTGAPVVPAFAYRLP-GGGYRIEFEPPLENPP 158

                        170       180       190
                 ....*....|....*....|....*....|....
gi 490380420 263 SSDALQDATIINSILEVEIMKAPEQYLWAHRRFK 296
Cdd:cd07984  159 SEDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
 
Name Accession Description Interval E-value
PRK08025 PRK08025
kdo(2)-lipid IV(A) palmitoleoyltransferase;
1-306 7.97e-159

kdo(2)-lipid IV(A) palmitoleoyltransferase;


Pssm-ID: 181200  Cd Length: 305  Bit Score: 444.95  E-value: 7.97e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   1 MYAKNPFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVN 80
Cdd:PRK08025   1 MFPQQKFSREFLHPRYWLTWFGLGVLWLLVQLPYPVLCFLGTRIGRMSRPFLKRRESIARKNLELCFPQMSAEEREKMIA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  81 DNLKSLGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKA 160
Cdd:PRK08025  81 ENFRSLGMALLETGMAWFWPDSRVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNKL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 161 MEYIQTKGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVT 240
Cdd:PRK08025 161 MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGPKGSSFAPFFAVENVATTNGTYVLSRLSGAAMLTVT 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490380420 241 LLRNKSGANYDLVLGKEILEYPsSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK08025 241 MVRKADYSGYRLFITPEMEGYP-TDENQAAAYMNKIIEKEIMRAPEQYLWIHRRFKTRPVGESSLY 305
lipid_A_htrB TIGR02207
lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow ...
 7-306 1.99e-147

lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase; This model represents a narrow clade of acyltransferases, nearly all of which transfer a lauroyl group to KDO2-lipid IV-A, a lipid A precursor; these proteins are termed lipid A biosynthesis lauroyl acyltransferase, HtrB. An exception is a closely related paralog of E. coli HtrB, LpxP, which acts in cold shock conditions by transferring a palmitoleoyl rather than lauroyl group to the lipid A precursor. Members of this family are homologous to the family of acyltransferases responsible for the next step in lipid A biosynthesis. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274031 [Multi-domain]  Cd Length: 303  Bit Score: 415.97  E-value: 1.99e-147
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420    7 FSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSL 86
Cdd:TIGR02207   3 FSASLLHPRYWPTWLGLGVLWLIVQLPYPVLLALGRGIGRLAMRLMKRRVHIARRNLELCFPHMSDAERERLLRENFEST 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   87 GIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQT 166
Cdd:TIGR02207  83 GMALFETGMAWFWSDARIKKWMQIEGLEHLQRAQKQGRGVLLVGVHFLTLELGARIFGQQQPGIGVYRPHNNPLFDWIQT 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  167 KGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVTLLRNKS 246
Cdd:TIGR02207 163 RGRLRSNKAMIDRKDLRGMIKALKNGERIWYAPDHDYGRKSSVFVPFFAVPDAATTTGTSILARLSKCAVVPFTPRRNED 242

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490380420  247 GANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRP-EGEVSLY 306
Cdd:TIGR02207 243 GSGYRLKIDPPLDDFPGDDEIAAAARMNKIVEKMIMRAPEQYMWLHRRFKTRPdEGESSLY 303
PRK06860 PRK06860
lipid A biosynthesis lauroyl acyltransferase; Provisional
 1-306 4.82e-136

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235880 [Multi-domain]  Cd Length: 309  Bit Score: 387.34  E-value: 4.82e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   1 MYAKNPFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVN 80
Cdd:PRK06860   3 MTNLPKFSRALLHPRYWLTWLGIGLLWLIVLLPYPVLYKLGRGLGKLALRFMKRRAKIARRNLELCFPEMSEQEREAIVV 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  81 DNLKSLGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKA 160
Cdd:PRK06860  83 KNFESVGMALIETGMAWFWPDWRIKRWTEVEGLEHIREVQAQGRGVLLVGVHFLTLELGARIFGMHNPGIGVYRPNDNPL 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 161 MEYIQTKGRCRSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSKGTSILAQLSKSPTLTVT 240
Cdd:PRK06860 163 YDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGERIWYAPDHDYGPRSSVFVPFFAVEQAATTTGTWMLARMSKAAVIPFV 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490380420 241 LLRNKSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK06860 243 PRRKPDGKGYELIILPPEDSPPLDDAEATAAWMNKVVEKCILMAPEQYMWLHRRFKTRPEGVPSRY 308
LpxP COG1560
Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and ...
 25-295 1.64e-102

Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) [Lipid transport and metabolism]; Palmitoleoyl-ACP: Kdo2-lipid-IV acyltransferase (lipid A biosynthesis) is part of the Pathway/BioSystem: Lipid A biosynthesis


Pssm-ID: 441168 [Multi-domain]  Cd Length: 271  Bit Score: 300.95  E-value: 1.64e-102
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  25 ILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWFWSDKKV 104
Cdd:COG1560    1 LLRLLRLLPLRLLYRLGDLLGRLLYRLAGRRRRVARRNLALAFPELSEAEREALARASFRNLGRTLLETLRLWRLSPERL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 105 KKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLC-FPVNAMYRPHNNKAMEYIQTKGRCRSGKGMIDRKN-L 182
Cdd:COG1560   81 RKRVEVEGLEHLEAALAEGRGVILLTPHFGNWELAGAALALRgYPVTAVYRPLKNPLLDRLIRRGRERFGGELIPRKDgV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 183 KFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRNKSGANYDLVLGKEIlEYP 262
Cdd:COG1560  161 RALLRALRKGGIVGLLPDQDPGRKSGVFVPFFGVP-AATPTGPARLARRTGAPVVPVFARRLPDGRGYRLEIEPPL-EDF 238

                        250       260       270
                 ....*....|....*....|....*....|...
gi 490380420 263 SSDALQDATIINSILEVEIMKAPEQYLWAHRRF 295
Cdd:COG1560  239 SEDVEADTQRLNRALEAWIREHPEQWLWLHRRW 271
PRK05646 PRK05646
lipid A biosynthesis lauroyl acyltransferase; Provisional
 7-306 2.00e-98

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 235543 [Multi-domain]  Cd Length: 310  Bit Score: 292.10  E-value: 2.00e-98
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   7 FSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSL 86
Cdd:PRK05646   6 FRAAFLHPRFWPLWLGLGLLWLVVQLPYRVLLWLGRALGALMYRLAGSRRRIAARNLELCFPEKSAAERERLLKENFAST 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  87 GIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQT 166
Cdd:PRK05646  86 GIAFFEMAMSWWWPKARLARLAHIEGLEHLQQAQQEGQGVILMALHFTTLEIGAALLGQQHTIDGMYREHKNPVFDFIQR 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 167 KGRCRSGKG--MIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRN 244
Cdd:PRK05646 166 RGRERHNLDstAIEREDVRGMLKLLRAGRAIWYAPDQDYGAKQSIFVPLFGIP-AATVTATTKFARLGRARVIPFTQKRL 244

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490380420 245 KSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK05646 245 ADGSGYRLVIHPPLEDFPGESEEADCLRINQWVERVVRECPEQYLWAHRRFKSRPEGEPKLY 306
Lip_A_acyltrans pfam03279
Bacterial lipid A biosynthesis acyltransferase;
6-297 7.25e-88

Bacterial lipid A biosynthesis acyltransferase;


Pssm-ID: 281296 [Multi-domain]  Cd Length: 294  Bit Score: 264.59  E-value: 7.25e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420    6 PFSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKS 85
Cdd:pfam03279   2 KFSPELLHPRYWLDWLGIAVLRLLALLPYSALRRIGKGLGRLAGRFLKRRRKIARRNLALCFPEMSEAEREQIIDKSFAS 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   86 LGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFP-VNAMYRPHNNKAMEYI 164
Cdd:pfam03279  82 VGRAIVETGRVWFWPDSRIAKRFEVIGLEHIKEALAQGRGAILVGPHFGNWDLGGRVLGQQYPgMAVYRPNLKNPLLDWL 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  165 QTKGRCRSGKGMIDRKN-LKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSSTSkGTSILAQLSKSPTLTVTLLR 243
Cdd:pfam03279 162 QTSGRERFGGRMLPRQNgIKGLIKALRKGEVVWYLPDQDLGRKDSVFVPFFGVPAATTT-GPAKLALKTKAAVIPVFPIR 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 490380420  244 NKSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKT 297
Cdd:pfam03279 241 NGDGSGYTVIVHPALDLTITDDVEQIAQAMNQIVEKFIMPAPEQYFWLHRRWKT 294
PRK08733 PRK08733
LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;
11-306 3.44e-63

LpxL/LpxP family Kdo(2)-lipid IV(A) lauroyl/palmitoleoyl acyltransferase;


Pssm-ID: 181542 [Multi-domain]  Cd Length: 306  Bit Score: 202.06  E-value: 3.44e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  11 LVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIAL 90
Cdd:PRK08733  13 LRNPKHWPMYLGLAVMVLAARLPWTLQRALGRGVGWVAMRLAGTRRRAAEVNLKLCFPEQDDAWRARLLRDSFDALGVGL 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  91 FETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQTKGRC 170
Cdd:PRK08733  93 FEFARAWWGSIDVIRPGVQIEGLEHLQQLQQQGRGVLLVSGHFMTLEMCGRLLCDHVPLAGMYRRHRNPVFEWAVKRGRL 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 171 RSGKGMIDRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPtlTVTLLRNKSGANY 250
Cdd:PRK08733 173 RYATHMFANEDLRATIKHLKRGGFLWYAPDQDMRGKDTVFVPFFGHP-ASTITATHQLARLTGCA--VVPYFHRREGGRY 249

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 490380420 251 DLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK08733 250 VLKIAPPLADFPSDDVIADTTRVNAAIEDMVREAPDQYLWIHRRFKRQPGGRSDFY 305
LPLAT_LABLAT-like cd07984
Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; ...
 105-296 1.04e-62

Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as lipid A biosynthesis lauroyl/myristoyl (LABLAT, HtrB) acyltransferases and similar proteins.


Pssm-ID: 153246 [Multi-domain]  Cd Length: 192  Bit Score: 196.67  E-value: 1.04e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 105 KKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLC-FPVNAMYRPHNNKAMEYIQTKGRCRSGKGMIDRKN-L 182
Cdd:cd07984    1 LKRVEREGLEHLEAALAKGKGVILLTAHFGNWELAGLALALLgYPVTVVYRPLKNPLLDRLITRGRERFGARLIPRGGgL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 183 KFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRNKsGANYDLVLGKEILEYP 262
Cdd:cd07984   81 RELIRALKKGEIVGILPDQDPGRKGGVFVPFFGRP-AATPTGPARLALKTGAPVVPAFAYRLP-GGGYRIEFEPPLENPP 158

                        170       180       190
                 ....*....|....*....|....*....|....
gi 490380420 263 SSDALQDATIINSILEVEIMKAPEQYLWAHRRFK 296
Cdd:cd07984  159 SEDVEEDTQRLNDALEAAIREHPEQWLWFHRRWK 192
lipid_A_msbB TIGR02208
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB ...
 7-306 1.13e-52

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; This family consists of MsbB in E. coli and closely related proteins in other species. MsbB is homologous to HtrB (TIGR02207) and acts immediately after it in the biosynthesis of KDO-2 lipid A (also called Re LPS and Re endotoxin). These two enzymes act after creation of KDO-2 lipid IV-A by addition of the KDO sugars. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 274032  Cd Length: 305  Bit Score: 174.61  E-value: 1.13e-52
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420    7 FSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSL 86
Cdd:TIGR02208   5 FQKSFLHPKYWGTWLGVFALVLLAFMPAKLRDPIAKVLAKFVGPIAKKPRGRARINLSACFPEKSEAERETIIDNNFATF 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   87 GIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIM-GLCFPVNAMYRPHNNKAMEYIQ 165
Cdd:TIGR02208  85 VQVMLSQAELAIRSKAHLRRRVNLMGLEHIEAAQAAGKPVIFLVPHGWAIDYAGLRLaSQGLPMVTMFNNHKNPLFDWLW 164

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  166 TKGRCRSGKGMIDRKN-LKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKNSsTSKGTSILAQLSKSPTLTVTLLRN 244
Cdd:TIGR02208 165 NRVRSRFGGHVYAREAgIKALLASLKRGESGYYLPDEDHGPEQSVFVPFFATYKA-TLPVVGRLAKAGNAQVVPVFPGYN 243

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490380420  245 KSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:TIGR02208 244 QVTGKFELTVRPAMATELSVDPEQEARAMNKEVEQFILPYPEQYMWILRLLKTRPDGEASIY 305
PRK06946 PRK06946
lipid A biosynthesis lauroyl acyltransferase; Provisional
 19-306 1.49e-48

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 180770 [Multi-domain]  Cd Length: 293  Bit Score: 163.70  E-value: 1.49e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  19 TWVGVFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWF 98
Cdd:PRK06946   6 TALAIGLLKLLAFLPYGLTARFGDGLGWLLYRIPSRRRRIVHTNLKLCFPDWSDARREELARRHFRHVIRSYVERSVQWF 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  99 WSDKKVKKLFQVKGMSNyLDAIAKnKGVIIVGVHFMSLELGG--RIMGLCFPVNAMYRPHNNKAMEYIQTKGRCRSGKGM 176
Cdd:PRK06946  86 GSEKKLEKLVQVDSAID-LTDPDG-PPTIFLGLHFVGIEAGSiwLNYSLRRRVGSLYTPMSNPLLDAIAKAARGRFGAEM 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 177 IDR-KNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVT--LLRNKSGanYDLV 253
Cdd:PRK06946 164 VSRaDSARQVLRWLRDGKPVMLGADMDFGLRDSTFVPFFGVP-ACTLTAVSRLARTGGAQVVPFIteVLPDYKG--YRLR 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 490380420 254 LGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK06946 241 VFKPWENYPTGDDDLDARRMNAFLEEQIRLMPEQYYWVHKRFKTRPPGEPSVY 293
PRK08706 PRK08706
lipid A biosynthesis lauroyl acyltransferase; Provisional
 24-306 2.55e-48

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 169557 [Multi-domain]  Cd Length: 289  Bit Score: 163.11  E-value: 2.55e-48
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  24 FILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWFWSDKK 103
Cdd:PRK08706   6 FVLYVLQFLPFALLHKLADLTGLLAYLLVKPRRRIGEINLAKCFPEWDEEKRKTVLKQHFKHMAKLMLEYGLYWYAPAGR 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 104 VKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQTKGRCRSGKGMI--DRKN 181
Cdd:PRK08706  86 LKSLVRYRNKHYLDDALAAGEKVIILYPHFTAFEMAVYALNQDVPLISMYSHQKNKILDEQILKGRNRYHNVFLigRTEG 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 182 LKFMVQEL-KSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVtLLRNKSGANYDLVLGKEILE 260
Cdd:PRK08706 166 LRALVKQFrKSSAPFLYLPDQDFGRNDSVFVDFFGIQ-TATITGLSRIAALANAKVIPA-IPVREADNTVTLHFYPAWDS 243

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 490380420 261 YPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK08706 244 FPSEDAQADAQRMNRFIEERVREHPEQYFWLHKRFKTRPEGSPDFY 289
PRK08943 PRK08943
lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated
 7-302 2.10e-42

lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase; Validated


Pssm-ID: 236355  Cd Length: 314  Bit Score: 148.09  E-value: 2.10e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420   7 FSLKLVHPKYVVTWVGVFILFLLVQLPYKWQMWLGAFLGsnsRYFIKRRVSIIKR---NLELCFPNKNKNEIDTLVNDNL 83
Cdd:PRK08943  14 FQKSFLHPRYWGTWLGIGALAGLALMPPRLRDPLAAKLG---RLVGKLAKKARRRariNLSLCFPEKSEAEREAIIDEMF 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  84 KSLGIALFETGIAWFWSDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIM---GLcfPVNAMYRPHNNKA 160
Cdd:PRK08943  91 ATAPQAMLMMAELALRSPKHLQRRVEWHGLEILEEARANGENVIFLVPHGWAIDIPAMLLasqGQ--PMAAMFHNQRNPL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 161 MEYIQTKGRCRSGKGMIDRKN-LKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFF-SVKnsSTSKGTSILAQLSKSPTLT 238
Cdd:PRK08943 169 FDWLWNRVRRRFGGRLHAREDgIKPFISSVRQGYWGYYLPDEDHGPEHSVFVDFFaTYK--ATLPGIGRLAKVCRARVVP 246

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490380420 239 VTLLRNKSGANYDLVLGKEILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGE 302
Cdd:PRK08943 247 LFPVYNGKTHRLDIEIRPPMDDLLSADDETIARRMNEEVEQFVGPHPEQYMWILKLLKTRKPGE 310
PRK05645 PRK05645
lysophospholipid acyltransferase;
21-306 5.85e-28

lysophospholipid acyltransferase;


Pssm-ID: 135493 [Multi-domain]  Cd Length: 295  Bit Score: 109.61  E-value: 5.85e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  21 VGVFILFLLvqLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWFWS 100
Cdd:PRK05645  10 VGALRLFAL--LPWRAVQGVGAGIGWLMWKLPNRSREVVRINLSKCFPELSPAELEKLVGQSLMDIGKTLTESACAWIWP 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 101 DKKVKKLF-QVKGMSNYLDAIAKNKGVIIVGVHFMSLE-LGGRIMGLCFPVnAMYRPHNNKAMEYIQTKGRCRSGKGMI- 177
Cdd:PRK05645  88 PQKSLELVrEVEGLEVLEQALASGKGVVGITSHLGNWEvLNHFYCSQCKPI-IFYRPPKLKAVDELLRKQRVQLGNRVAp 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 178 -DRKNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSVKnSSTSKGTSILAQLSKSPTLTVTLLRNKSGANYDLVLGK 256
Cdd:PRK05645 167 sTKEGILSVIKEVRKGGQVGIPADPEPAESAGIFVPFLGTQ-ALTSKFVPNMLAGGKAVGVFLHALRLPDGSGYKVILEA 245

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 490380420 257 EILEYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEGEVSLY 306
Cdd:PRK05645 246 APEDMYSTDVEVSAAAMSKVVERYVRAYPSQYMWSMKRFKKRPAGEARWY 295
PRK08905 PRK08905
lysophospholipid acyltransferase family protein;
23-301 1.36e-27

lysophospholipid acyltransferase family protein;


Pssm-ID: 236348 [Multi-domain]  Cd Length: 289  Bit Score: 108.54  E-value: 1.36e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  23 VFILFLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNknknEIDTLVNDNLKSLGIALFETGIAWFWS-D 101
Cdd:PRK08905   3 TFLFRLLSRLPLSWLHALGGWLGRLAYRLPGRYRRRLRANLRQAGGD----PDPAMVKAAAAETGRMILELPYVWFRKpE 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 102 KKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAMEYIQTKGRCRSGKGMI--DR 179
Cdd:PRK08905  79 EIETMVKDDHGWEHVEAALAEGRGILFLTPHLGCFEVTARYIAQRFPLTAMFRPPRKAALRPLMEAGRARGNMRTApaTP 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 180 KNLKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSvKNSSTSKGTSILAQLSKSPTLTVTLLRNKSGANYDLVLgKEIL 259
Cdd:PRK08905 159 QGVRMLVKALRRGEAVGILPDQVPSGGEGVWAPFFG-RPAYTMTLVARLAEVTGVPVIFVAGERLPRGRGYRLHL-RPVQ 236

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 490380420 260 EYPSSDALQDATIINSILEVEIMKAPEQYLWAHRRFKtRPEG 301
Cdd:PRK08905 237 EPLPGDKAADAAVINAEIERLIRRFPTQYLWGYNRYK-RPRG 277
PRK08419 PRK08419
lipid A biosynthesis lauroyl acyltransferase; Reviewed
 22-296 1.11e-22

lipid A biosynthesis lauroyl acyltransferase; Reviewed


Pssm-ID: 181420 [Multi-domain]  Cd Length: 298  Bit Score: 95.48  E-value: 1.11e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  22 GVFIL-FLLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFP-NKNKNEIDTLVNDNLKSLGIALFETGIAWFW 99
Cdd:PRK08419   9 LFYILkFFLAKMPHCIFLRLAKALAFIMRYLDKKRRKIAKANLDFCFGeSKSQEEKKRIIKKCYENFAFFGLDFIRNQNT 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 100 SDKKVKKLFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCF-PVNAMYRPHNNKAMEYIQTKGRCRSGKGMID 178
Cdd:PRK08419  89 TKEEILNKVTFINEENLLDALKKKRPIIVTTAHYGYWELFSLALAAYYgAVSIVGRLLKSAPINEMISKRREQFGIELID 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 179 RKN-LKFMVQELKSGKSIWFAPDQDFGRKGTIFAPFFSvKNSSTSKGTSILAQLSKSPTLTVTlLRNKSGANYDLVLGKE 257
Cdd:PRK08419 169 KKGaMKELLKALKQGRALGILVDQNVVPKEGVEVKFFN-KRVTHTTIASILARRYNALIIPVF-IFNDDYSHFTITFFPP 246

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|...
gi 490380420 258 ILEYPSSDALQD---ATIIN-SILEVEIMKAPEQYLWAHRRFK 296
Cdd:PRK08419 247 IRSKITDDAEADileATQAQaSACEEMIRKKPDEYFWFHRRFK 289
PRK08734 PRK08734
lauroyl acyltransferase;
28-301 6.41e-19

lauroyl acyltransferase;


Pssm-ID: 181543 [Multi-domain]  Cd Length: 305  Bit Score: 84.93  E-value: 6.41e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  28 LLVQLPYKWQMWLGAFLGSNSRYFIKRRVSIIKRNLELCFPNKNKNEIDTLVNDNLKSLGIALFETGIAWFWSD-KKVKK 106
Cdd:PRK08734  16 LVGRLPWPLLKRLADLLAWSWRKLNARESRVTRRNLELAYPELSPQQRAQLHAQILRSTARQALEVLRTWTHPPaENLAR 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 107 LFQVKGMSNYLDAIAKNKGVIIVGVHFMSLELGGRIMGLCFPVNAMYRPHNNKAME-YIQtkgRCRSG--------KGMI 177
Cdd:PRK08734  96 LRQRHGQELYDAALASGRGVIVAAPHFGNWELLNQWLSERGPIAIVYRPPESEAVDgFLQ---LVRGGdnvrqvraEGPA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 178 DRKNLKFmvqeLKSGKSIWFAPDQDFGRKGTIFAPFFSVknsstskgtsilaqlsksPTLTVTL---LRNKSGANY---- 250
Cdd:PRK08734 173 VRQLFKV----LKDGGAVGILPDQQPKMGDGVFAPFFGI------------------PALTMTLvnrLAERTGATVlygw 230

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490380420 251 ------DLVLGKEILEYPSS----DALQDATIINSILEVEIMKAPEQYLWAHRRFKTRPEG 301
Cdd:PRK08734 231 cerigpDLEFALHVQPADPAvadpDPLRAATALNAGIERIARRDPAQYQWTYKRYTLRPPG 291
PRK06628 PRK06628
lipid A biosynthesis lauroyl acyltransferase; Provisional
 51-296 8.22e-04

lipid A biosynthesis lauroyl acyltransferase; Provisional


Pssm-ID: 102471  Cd Length: 290  Bit Score: 40.30  E-value: 8.22e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420  51 FIKRRVSII-------KRNLELCFpnKNKNEIDTLVNDNLKSLGIALFETGIAWFWSDKKVKKLFQVKGMSNyldaIAKN 123
Cdd:PRK06628  38 FIARKVGILfavnkiaRRNIKAVF--GDMCDVEKIIDQTWDNFGRFIGEFTYVNKMDEAELERRIEIIGIEN----IKKL 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 124 KG--VIIVGVHFMSLELGGRIMGLCFP-VNAMYRPHNNKAMEYIQTKGRCRSGKGMIDR--KNLKFMVQELKSGKSIWFA 198
Cdd:PRK06628 112 EGqpFLLFSGHFANWDISLKILHKFYPkVAVIYRKANNPYVNKLVNESRAGDKLRLIPKgpEGSRALVRAIKESESIVML 191

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490380420 199 PDQDFgrKGTIFAPFFSvKNSSTSKGTSILAQLSKSPTLTVTLLRNKsGANYDLVLGKEILEYPSSDALQDA----TIIN 274
Cdd:PRK06628 192 VDQKM--NDGIEVPFLG-HPAMTASAIAKIALQYKYPIIPCQIIRTK-GSYFKVIVHPQLKFEQTGDNKADCynimLNIN 267

                        250       260
                 ....*....|....*....|..
gi 490380420 275 SILEVEIMKAPEQYLWAHRRFK 296
Cdd:PRK06628 268 QMLGEWVKQNPAQWFWFHNRWK 289
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH