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Conserved domains on  [gi|490386801|ref|WP_004266256|]
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MULTISPECIES: UxaA family hydrolase [Burkholderia]

Protein Classification

UxaA family hydrolase( domain architecture ID 10184262)

UxaA family hydrolase similar to Chromohalobacter salexigens (2R)-sulfolactate sulfo-lyase subunit alpha (SuyA) that, together with SuyB, esulfonates sulfolactate to form pyruvate and sulfite

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
SAF_AH_GD cd11613
Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) ...
 9-87 1.11e-29

Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) converts D-altronate into 2-dehydro-3-deoxy-D-gluconate and is part of a bacterial pathway for the degradation of D-galacturonate. D-galactarate dehydratase (EC 4.2.1.42) eliminates water from D-galactarate to yield 5-dehydro-4-deoxy-D-glucarate, initializing the degradation of D-galactarate. The function of the SAF domain in these enzymes is not clear. It may participate in dimerization.


:

Pssm-ID: 212158  Cd Length: 80  Bit Score: 101.35  E-value: 1.11e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490386801   9 RLLLLSPADNCLIAATRLCAGQAVTIDGERVVLAQTVELGHKIARAPLAANDKVLRYGAPIGHVTREVARGEHLHTHNL 87
Cdd:cd11613    1 KAIKLHPKDNVAVALRDLKAGEVVEVDGEGVTLLEDIPAGHKIALRDIAAGEPVIKYGEPIGKATRDIAAGEHVHTHNV 79
 
Name Accession Description Interval E-value
SAF_AH_GD cd11613
Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) ...
 9-87 1.11e-29

Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) converts D-altronate into 2-dehydro-3-deoxy-D-gluconate and is part of a bacterial pathway for the degradation of D-galacturonate. D-galactarate dehydratase (EC 4.2.1.42) eliminates water from D-galactarate to yield 5-dehydro-4-deoxy-D-glucarate, initializing the degradation of D-galactarate. The function of the SAF domain in these enzymes is not clear. It may participate in dimerization.


Pssm-ID: 212158  Cd Length: 80  Bit Score: 101.35  E-value: 1.11e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490386801   9 RLLLLSPADNCLIAATRLCAGQAVTIDGERVVLAQTVELGHKIARAPLAANDKVLRYGAPIGHVTREVARGEHLHTHNL 87
Cdd:cd11613    1 KAIKLHPKDNVAVALRDLKAGEVVEVDGEGVTLLEDIPAGHKIALRDIAAGEPVIKYGEPIGKATRDIAAGEHVHTHNV 79
UxaA COG2721
Altronate dehydratase [Carbohydrate transport and metabolism];
8-88 4.70e-10

Altronate dehydratase [Carbohydrate transport and metabolism];


Pssm-ID: 442034 [Multi-domain]  Cd Length: 498  Bit Score: 54.81  E-value: 4.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490386801   8 ARLLLLSPADNCLIAATRLCAGQAVTIDGERVVLAQTVELGHKIARAPLAANDKVLRYGAPIGHVTREVARGEHLHTHNL 87
Cdd:COG2721    1 MKLLIIHHDDDVVVAVVDLAGGGEGTVGGGGVTLLEDVPAGHKKAAADIAAGGEVVKYGVVIGGAAADIPAGGWVHHHNN 80


                 .
gi 490386801  88 V 88
Cdd:COG2721   81 N 81
SAF smart00858
This domain family includes a range of different proteins. Such as antifreeze proteins and ...
 17-88 3.46e-05

This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins;


Pssm-ID: 214862 [Multi-domain]  Cd Length: 63  Bit Score: 38.32  E-value: 3.46e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490386801    17 DNCLIAATRLCAGQAVTIDGervvlaqtVELGHKIARAplAANDKVLRYGAPIG-HVTREVARGEHLHTHNLV 88
Cdd:smart00858   1 DNVVVAARDLPAGEVITAED--------LRLGHVALRD--LPGGGLTPYGQVIGrVARRDIAAGEPITASNLE 63
SAF pfam08666
SAF domain; This domain family includes a range of different proteins. Such as antifreeze ...
 17-88 2.10e-04

SAF domain; This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


Pssm-ID: 430140 [Multi-domain]  Cd Length: 63  Bit Score: 36.38  E-value: 2.10e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490386801   17 DNCLIAATRLCAGQavTIDGERVVLAQtVELGHKIARAPLAandkvlrYGAPIG-HVTREVARGEHLHTHNLV 88
Cdd:pfam08666   1 DNVVVAARDLPAGE--VITADDLTLVR-PPLALPPGLFPIA-------YGEVIGkVARRDIAAGEPLTASDLE 63
 
Name Accession Description Interval E-value
SAF_AH_GD cd11613
Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) ...
 9-87 1.11e-29

Domains similar to fish antifreeze type III protein; Altronate dehydratase (EC 4.2.1.7) converts D-altronate into 2-dehydro-3-deoxy-D-gluconate and is part of a bacterial pathway for the degradation of D-galacturonate. D-galactarate dehydratase (EC 4.2.1.42) eliminates water from D-galactarate to yield 5-dehydro-4-deoxy-D-glucarate, initializing the degradation of D-galactarate. The function of the SAF domain in these enzymes is not clear. It may participate in dimerization.


Pssm-ID: 212158  Cd Length: 80  Bit Score: 101.35  E-value: 1.11e-29
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490386801   9 RLLLLSPADNCLIAATRLCAGQAVTIDGERVVLAQTVELGHKIARAPLAANDKVLRYGAPIGHVTREVARGEHLHTHNL 87
Cdd:cd11613    1 KAIKLHPKDNVAVALRDLKAGEVVEVDGEGVTLLEDIPAGHKIALRDIAAGEPVIKYGEPIGKATRDIAAGEHVHTHNV 79
UxaA COG2721
Altronate dehydratase [Carbohydrate transport and metabolism];
8-88 4.70e-10

Altronate dehydratase [Carbohydrate transport and metabolism];


Pssm-ID: 442034 [Multi-domain]  Cd Length: 498  Bit Score: 54.81  E-value: 4.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490386801   8 ARLLLLSPADNCLIAATRLCAGQAVTIDGERVVLAQTVELGHKIARAPLAANDKVLRYGAPIGHVTREVARGEHLHTHNL 87
Cdd:COG2721    1 MKLLIIHHDDDVVVAVVDLAGGGEGTVGGGGVTLLEDVPAGHKKAAADIAAGGEVVKYGVVIGGAAADIPAGGWVHHHNN 80


                 .
gi 490386801  88 V 88
Cdd:COG2721   81 N 81
SAF smart00858
This domain family includes a range of different proteins. Such as antifreeze proteins and ...
 17-88 3.46e-05

This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins;


Pssm-ID: 214862 [Multi-domain]  Cd Length: 63  Bit Score: 38.32  E-value: 3.46e-05
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490386801    17 DNCLIAATRLCAGQAVTIDGervvlaqtVELGHKIARAplAANDKVLRYGAPIG-HVTREVARGEHLHTHNLV 88
Cdd:smart00858   1 DNVVVAARDLPAGEVITAED--------LRLGHVALRD--LPGGGLTPYGQVIGrVARRDIAAGEPITASNLE 63
SAF pfam08666
SAF domain; This domain family includes a range of different proteins. Such as antifreeze ...
 17-88 2.10e-04

SAF domain; This domain family includes a range of different proteins. Such as antifreeze proteins and flagellar FlgA proteins, and CpaB pilus proteins.


Pssm-ID: 430140 [Multi-domain]  Cd Length: 63  Bit Score: 36.38  E-value: 2.10e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490386801   17 DNCLIAATRLCAGQavTIDGERVVLAQtVELGHKIARAPLAandkvlrYGAPIG-HVTREVARGEHLHTHNLV 88
Cdd:pfam08666   1 DNVVVAARDLPAGE--VITADDLTLVR-PPLALPPGLFPIA-------YGEVIGkVARRDIAAGEPLTASDLE 63
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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