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Conserved domains on  [gi|490515587|ref|WP_004381149|]
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isoprenyl transferase [Segatella oulorum]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-245 2.82e-151

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 421.39  E-value: 2.82e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqAARQEGRP 163
Cdd:COG0020   90 YLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARD--VAAGELDP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 164 EPpITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGA 243
Cdd:COG0020  168 ED-IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSE 246


                 ..
gi 490515587 244 QI 245
Cdd:COG0020  247 QV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-245 2.82e-151

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 421.39  E-value: 2.82e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqAARQEGRP 163
Cdd:COG0020   90 YLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARD--VAAGELDP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 164 EPpITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGA 243
Cdd:COG0020  168 ED-IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSE 246


                 ..
gi 490515587 244 QI 245
Cdd:COG0020  247 QV 248
PRK14838 PRK14838
isoprenyl transferase;
6-246 7.34e-149

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 415.04  E-value: 7.34e-149
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:PRK14838   5 IDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAArqEGRPEp 165
Cdd:PRK14838  85 SIEEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNG--ELNPE- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 166 PITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGAQI 245
Cdd:PRK14838 162 EITEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQI 241


                 .
gi 490515587 246 D 246
Cdd:PRK14838 242 S 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 18-239 2.16e-135

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 380.17  E-value: 2.16e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   18 IMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGL-VLTSLEDEI--FMK 94
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELlKEEYLRRELpeLHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   95 NNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqaaRQEGRPEPpITEETLAQ 174
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKE----GKKLDPED-IDEELISS 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490515587  175 HLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:pfam01255 156 HLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 14-233 3.46e-132

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 371.71  E-value: 3.46e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  14 HIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI-- 91
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELee 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  92 FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAarQEGRPEpPITEET 171
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKA--GELDPE-DITEEL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490515587 172 LAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQH 233
Cdd:cd00475  158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 13-239 5.86e-100

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 290.84  E-value: 5.86e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   13 QHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI- 91
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   92 -FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQaaRQEGRPEPpITEE 170
Cdd:TIGR00055  81 eLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVK--SGKLLPED-IDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490515587  171 TLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
6-245 2.82e-151

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 421.39  E-value: 2.82e-151
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:COG0020   10 IDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMGLLRE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqAARQEGRP 163
Cdd:COG0020   90 YLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARD--VAAGELDP 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 164 EPpITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGA 243
Cdd:COG0020  168 ED-IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRERRFGGTSE 246


                 ..
gi 490515587 244 QI 245
Cdd:COG0020  247 QV 248
PRK14838 PRK14838
isoprenyl transferase;
6-246 7.34e-149

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 415.04  E-value: 7.34e-149
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:PRK14838   5 IDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMSLLLD 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAArqEGRPEp 165
Cdd:PRK14838  85 SIEEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNG--ELNPE- 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 166 PITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGAQI 245
Cdd:PRK14838 162 EITEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRFGKTSEQI 241


                 .
gi 490515587 246 D 246
Cdd:PRK14838 242 S 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 18-239 2.16e-135

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 380.17  E-value: 2.16e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   18 IMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGL-VLTSLEDEI--FMK 94
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELlKEEYLRRELpeLHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   95 NNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqaaRQEGRPEPpITEETLAQ 174
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKE----GKKLDPED-IDEELISS 155

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490515587  175 HLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:pfam01255 156 HLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 14-233 3.46e-132

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 371.71  E-value: 3.46e-132
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  14 HIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI-- 91
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELee 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  92 FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAarQEGRPEpPITEET 171
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKA--GELDPE-DITEEL 157

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490515587 172 LAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQH 233
Cdd:cd00475  158 ISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 1-241 6.74e-127

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 359.96  E-value: 6.74e-127
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   1 MNELSLDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALM 80
Cdd:PRK14830  12 SFDEELDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLM 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  81 GLVLTSLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAAR 158
Cdd:PRK14830  92 NLPVEFLDKFVpeLIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGK 171

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 159 QegRPEPpITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRF 238
Cdd:PRK14830 172 L--NPED-ITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRF 248


                 ...
gi 490515587 239 GKT 241
Cdd:PRK14830 249 GGV 251
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 10-250 2.89e-112

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 322.79  E-value: 2.89e-112
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  10 KIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLED 89
Cdd:PRK14836  13 NIPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKALDR 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  90 EI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAARQegRPEpPI 167
Cdd:PRK14836  93 EVdkLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKL--APD-EI 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 168 TEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGAQIDA 247
Cdd:PRK14836 170 DEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQIAD 249


                 ...
gi 490515587 248 EAP 250
Cdd:PRK14836 250 RAT 252
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 13-239 5.86e-100

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 290.84  E-value: 5.86e-100
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   13 QHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI- 91
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   92 -FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQaaRQEGRPEPpITEE 170
Cdd:TIGR00055  81 eLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVK--SGKLLPED-IDEE 157

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490515587  171 TLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:TIGR00055 158 TLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 6-240 3.82e-97

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 284.53  E-value: 3.82e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:PRK14831  15 LDPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFER 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVaeQQAARQEGRP 163
Cdd:PRK14831  95 VLRRELeeLMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIA--QQVQQGELDP 172

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490515587 164 EPpITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGK 240
Cdd:PRK14831 173 SE-IDENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14834 PRK14834
isoprenyl transferase;
7-243 3.12e-95

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 279.72  E-value: 3.12e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   7 DRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTS 86
Cdd:PRK14834  10 DAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLLRLF 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  87 LEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQqaarQEGRPE 164
Cdd:PRK14834  90 IRRDLaeLHRNGVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREV----AEGRLD 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 165 PP-ITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG---- 239
Cdd:PRK14834 166 PAsIDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRERRFGglaa 245


                 ....
gi 490515587 240 KTGA 243
Cdd:PRK14834 246 KTGA 249
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
12-239 1.35e-88

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 262.06  E-value: 1.35e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  12 PQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDE- 90
Cdd:PRK14833   5 LKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYLKDEr 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  91 -IFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVaeQQAARQEGRPEppITE 169
Cdd:PRK14833  85 sTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKLL--ESPPSHIGELE--SLE 160

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 170 ETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:PRK14833 161 EEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
19-249 5.74e-82

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 245.28  E-value: 5.74e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  19 MDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI--FMKNN 96
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVksLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  97 VRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIvAEQQaarQEGRPEPP-ITEETLAQH 175
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQL-AEQV---QQGNLQPDqIDEEMLNQH 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490515587 176 LCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTgAQIDAEA 249
Cdd:PRK10240 157 ICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGT-EPGDETA 229
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 6-247 1.09e-76

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 232.58  E-value: 1.09e-76
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLT 85
Cdd:PRK14832  13 LDPQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFER 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKiVAEQQaarQEGRP 163
Cdd:PRK14832  93 LLRRELaqMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQ-VAELV---QQGKL 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 164 EP-PITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTG 242
Cdd:PRK14832 169 SAdAVNEQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQVK 248


                 ....*
gi 490515587 243 AQIDA 247
Cdd:PRK14832 249 ALIPA 253
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 10-242 4.29e-75

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 227.95  E-value: 4.29e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  10 KIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSL-- 87
Cdd:PRK14841   2 RIPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIdr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  88 EDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqaARQEGRPEppI 167
Cdd:PRK14841  82 EMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKD---VSQGKKIE--L 156

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490515587 168 TEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTG 242
Cdd:PRK14841 157 TEETFRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFGGLI 231
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 2-240 8.73e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 222.41  E-value: 8.73e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   2 NELSLDRtkIPQHIAIIMDGNGRWAAEKGQPRRY----GHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEIS 77
Cdd:PRK14840  11 NFPSLQS--LPRHVAIIMDGNRRWYRKHEQFCQKraisGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVA 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  78 ALMGLVLTSLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKI---VA 152
Cdd:PRK14840  89 ELFSLFNSQLDSQLpyLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLhqdLA 168

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 153 EQQAARQEgrpeppITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQ 232
Cdd:PRK14840 169 NKKISSDD------ISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQ 242


                 ....*...
gi 490515587 233 HRQRRFGK 240
Cdd:PRK14840 243 QRSRRGGK 250
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
14-251 2.58e-72

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 220.78  E-value: 2.58e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  14 HIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSLEDEI-- 91
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETer 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  92 FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRweitqavQKIVAeqqAARQEGRPEPPiTEET 171
Cdd:PRK14839  92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSAR-------DAILA---AAAKALGPEGL-SREA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 172 LAQHLCTNfMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKTGAQIDAEAPT 251
Cdd:PRK14839 161 FSDLLTGD-GGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFGGLPAPAVPAAAS 239
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 8-241 3.10e-72

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 220.81  E-value: 3.10e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   8 RTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSL 87
Cdd:PRK14829  11 KNKLPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVI 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  88 --EDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVaeQQAARQEGRPEp 165
Cdd:PRK14829  91 hrRREQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIA--REVRDGKISGD- 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490515587 166 PITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGKT 241
Cdd:PRK14829 168 RVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 6-240 3.39e-68

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 211.14  E-value: 3.39e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   6 LDRTKIPQHIAIIMDGNGRWAAEKGQPR-RYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGlVL 84
Cdd:PRK14828  21 LDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLLD-II 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  85 TSLEDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEqqaARQEGRPE 164
Cdd:PRK14828 100 EDVVRQLAPDGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTE---HKDKGTSI 176

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 165 P----PITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGK 240
Cdd:PRK14828 177 DelaeSVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERRFGK 256
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 4-239 5.81e-68

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 209.84  E-value: 5.81e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   4 LSLDRTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLV 83
Cdd:PRK14842   1 MGLFESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  84 LTSLEDEI--FMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAARQEg 161
Cdd:PRK14842  81 VEFIETRLdtIHARGIRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVT- 159

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490515587 162 rPEPPITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFG 239
Cdd:PRK14842 160 -LEKPLKEKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 10-240 3.49e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 207.12  E-value: 3.49e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  10 KIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGL--VLTSL 87
Cdd:PRK14827  66 RLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVVIDIACGAIELGIKWLSLYAFSTENWKRSPEEVRFLMGFnrDVVRR 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  88 EDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAarqeGRPEPP- 166
Cdd:PRK14827 146 RRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAA----GRLNPEr 221

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490515587 167 ITEETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGK 240
Cdd:PRK14827 222 ITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK14835 PRK14835
isoprenyl transferase;
8-240 9.88e-64

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 200.45  E-value: 9.88e-64
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   8 RTKIPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGLVLTSL 87
Cdd:PRK14835  38 HGKLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREA 117

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  88 E----DEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQQAARQEgrP 163
Cdd:PRK14835 118 RrmavDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATGKS--P 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 164 EPPITE---ETLAQHLCTNFMPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQHRQRRFGK 240
Cdd:PRK14835 196 EEVAAEltpEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 1-240 1.99e-59

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 187.72  E-value: 1.99e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   1 MNELSLdrtkiPQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALM 80
Cdd:PRK14837   1 MNKNSL-----PSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLM 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  81 GLVLTSL--EDEIFMKNNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEITQAVQKIVAEQqaar 158
Cdd:PRK14837  76 FLIADYLssEFNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFLSSG---- 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 159 qegrpeppITEETLAQHLCTNF-----MPDPDLLIRTGGELRVSNYLLWQIAYSELYFCDTYWPDFKEEDLHKAIANYQH 233
Cdd:PRK14837 152 --------LDLETLNENVFSKFldnpeLPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKN 223


                 ....*..
gi 490515587 234 RQRRFGK 240
Cdd:PRK14837 224 RKRNFGR 230
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 7-219 7.71e-35

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 127.03  E-value: 7.71e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587   7 DRTKIpQHIAIIMDGNGRWAAEKGQPRRYGHQAGVDAVKKIAAEATRLGVKYLTLYTFSTENWNRPADEISALMGL-VLT 85
Cdd:PTZ00349  16 DFINI-KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLnLLI 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587  86 SLEDEIFMK----NNVRFRVMGELSRLPEDVRQKLHETEERTKHNDTMTMVVALSYSSRWEIT----------QAVQKIV 151
Cdd:PTZ00349  95 LINEDFFFKfikdNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMSlckfnpnlyfDTYKNLL 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490515587 152 AEQQAARQEGRPEPPITEETLA-------------------------------------------------QHLCTNFMP 182
Cdd:PTZ00349 175 EEKKILCGSNILTDPIKEGTFAipddedecdyldheleneridldlkfdgdcicgeksflneeqieivnyhKKLLTSDLP 254

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 490515587 183 DPDLLIRTGGELRVSNYLLWQIA-YSELYFCDTYWPDF 219
Cdd:PTZ00349 255 PPNILIRTSGEKRLSDFMLYQISeFTEIYFINEYWPIF 292
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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