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Conserved domains on  [gi|490519937|ref|WP_004385421|]
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MULTISPECIES: porin OmpA [Cronobacter]

Protein Classification

porin OmpA( domain architecture ID 11484960)

outer membrane protein A (OmpA) acts as a porin with low permeability that allows slow penetration of small solutes; OmpA is required for the action of colicins K and L and for the stabilization of mating aggregates in conjugation

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10808 PRK10808
outer membrane protein A; Reviewed
 1-347 0e+00

outer membrane protein A; Reviewed


:

Pssm-ID: 236764 [Multi-domain]  Cd Length: 351  Bit Score: 715.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQFHDTGF--IPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDW 78
Cdd:PRK10808   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGGKLGWSQYHDTGYgfINNNGPTHKNQLGAGAFGGYQANPYLGFEMGYDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  79 LGRMPYKGDTVNGAFKAQGVQLTAKLGYPVTDDLDVYTRLGGMVWRADSSSNIGGD---DHDTGVSPVFAGGVEWAMTRD 155
Cdd:PRK10808  81 LGRMPYKGDVNNGAFKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVPGArgkDHDTGVSPVFAGGVEYAITKN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 156 IATRLEYQWVNNIGDAQTVGARPDNGMLSVGVSYRFGQQEdAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEG 235
Cdd:PRK10808 161 WATRLEYQWTNNIGDADTVGARPDNGMLSVGVSYRFGQEE-AAPVVAPAPAPAPVVQTKHFTLKSDVLFNFNKATLKPEG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 236 QQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARGMGESNPVTGNTCDNV 315
Cdd:PRK10808 240 QQALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSEKRAQSVVDYLVSKGIPADKISARGMGKSNPVTGNTCDNV 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 490519937 316 KPRAALIECLGPDRRVEIEVKGVKDVVTQPQA 347
Cdd:PRK10808 320 KPRAALIDCLAPDRRVEIEVKGIKDVVTQPQA 351
 
Name Accession Description Interval E-value
PRK10808 PRK10808
outer membrane protein A; Reviewed
 1-347 0e+00

outer membrane protein A; Reviewed


Pssm-ID: 236764 [Multi-domain]  Cd Length: 351  Bit Score: 715.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQFHDTGF--IPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDW 78
Cdd:PRK10808   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGGKLGWSQYHDTGYgfINNNGPTHKNQLGAGAFGGYQANPYLGFEMGYDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  79 LGRMPYKGDTVNGAFKAQGVQLTAKLGYPVTDDLDVYTRLGGMVWRADSSSNIGGD---DHDTGVSPVFAGGVEWAMTRD 155
Cdd:PRK10808  81 LGRMPYKGDVNNGAFKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVPGArgkDHDTGVSPVFAGGVEYAITKN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 156 IATRLEYQWVNNIGDAQTVGARPDNGMLSVGVSYRFGQQEdAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEG 235
Cdd:PRK10808 161 WATRLEYQWTNNIGDADTVGARPDNGMLSVGVSYRFGQEE-AAPVVAPAPAPAPVVQTKHFTLKSDVLFNFNKATLKPEG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 236 QQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARGMGESNPVTGNTCDNV 315
Cdd:PRK10808 240 QQALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSEKRAQSVVDYLVSKGIPADKISARGMGKSNPVTGNTCDNV 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 490519937 316 KPRAALIECLGPDRRVEIEVKGVKDVVTQPQA 347
Cdd:PRK10808 320 KPRAALIDCLAPDRRVEIEVKGIKDVVTQPQA 351
OmpA_membrane pfam01389
OmpA-like transmembrane domain; The structure of OmpA transmembrane domain shows that it ...
 23-195 1.52e-94

OmpA-like transmembrane domain; The structure of OmpA transmembrane domain shows that it consists of an eight stranded beta barrel. This family includes some other distantly related outer membrane proteins with low scores.


Pssm-ID: 396112  Cd Length: 177  Bit Score: 278.94  E-value: 1.52e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   23 PKDNTWYAGGKLGWSQFHDTGFIPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDTVNGAFKAQGVQLTA 102
Cdd:pfam01389   1 PAANTWYTGAKAGWASFHDTGNIEGNGPTHENSLTAGAFGGYQINNYLAAELGYDYLGRMPYKGKGKNNAHKAQGVTLSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  103 KLGYPVTDDLDVYTRLGGMVWRADSSSNIG----GDDHDTGVSPVFAGGVEWAMTRDIATRLEYQWVNNIGDAQTVGARP 178
Cdd:pfam01389  81 KLSYPLTDDLDVYGKVGGALVRADYKFYEDangkTGNHDTGVSPLFALGVEYAITPELAVRLEYQYLNNIGDLHKQGKRP 160

                         170
                  ....*....|....*..
gi 490519937  179 DNGMLSVGVSYRFGQQE 195
Cdd:pfam01389 161 DNGSASLGISYRFGQGE 177
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 221-335 2.43e-38

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 132.29  E-value: 2.43e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 221 DVLFNFNKATLKPEGQQALDQLYSQLSNLDpkDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARG 300
Cdd:cd07185    3 TIYFDFGSAELTPEAKPLLDKLAEVLKKNP--DAKIRIEGHTDSRGSDAYNQELSERRAEAVADYLVSKGVDASRITAVG 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490519937 301 MGESNPVTGNtcdnvkpraALIECLGPDRRVEIEV 335
Cdd:cd07185   81 YGESRPIASN---------DTEEGRAKNRRVEIVI 106
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 39-337 9.45e-38

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 136.84  E-value: 9.45e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  39 FHDTGFIPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDTVNGAFKAQGVQLTAKLGYPVTDDLDVYTRL 118
Cdd:COG2885    2 SEAALGASALAIDAAGGLLSGAALLLALLGVLGSAGGLLSLADDLAEASAGAAGGAAAGAEAGGLSAGLELLDAGSLSAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 119 GGMVWRADSSSNIGGDDHDTGVSPVFAGGVEWAMTRDIATRLEYQWVNNIGDAQTVGARPDNGMLSV----GVSYRFGQQ 194
Cdd:COG2885   82 AAAGAAALLVLLAALGALGAGLAALLLAIAAAASAAAADALALAAGAAAALGALGASAAAAAAALAAakalGDSAAAALD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 195 EDAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLdpKDGSVVVLGFTDRIGSDAYNQGL 274
Cdd:COG2885  162 AAAKAEAAAAAAALLPAAVAEVVLLSNVYFDFDSAELTPEAKAALDELAALLKEN--PDLRIEIEGHTDSRGSDAYNLAL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490519937 275 SEKRAQSVVDYLISKGIPSNKISARGMGESNPVtgNTCDNVKPRAAlieclgpDRRVEIEVKG 337
Cdd:COG2885  240 SERRAEAVKDYLVSKGIPASRITAVGYGESRPV--ASNDTEEGRAK-------NRRVEIVVLK 293
pdsO TIGR03789
proteobacterial sortase system peptidoglycan-associated protein; A newly defined histidine ...
 210-307 2.79e-12

proteobacterial sortase system peptidoglycan-associated protein; A newly defined histidine kinase (TIGR03785) and response regulator (TIGR03787) gene pair occurs exclusively in Proteobacteria, mostly of marine origin, nearly all of which contain a subfamily 6 sortase (TIGR03784) and its single dedicated target protein (TIGR03788) adjacent to to the sortase. This protein family shows up in only in those species with the histidine kinase/response regulator gene pair, and often adjacent to that pair. It belongs to the pfam00691 domain family, which is the peptidoglycan-associated region of flagellar motor protein MotB, OmpA (whose N-terminal region forms an outer membrane beta barrel), and peptidoglycan-associated lipoprotein Pal. Its function is unknown. We assign the gene symbol pdsO, for Proteobacterial Dedicated Sortase system OmpA family protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274783 [Multi-domain]  Cd Length: 243  Bit Score: 65.60  E-value: 2.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  210 EVQTKHFTLKSDVLFNFNKATLKPEGQQALDQLySQLSNLDPkDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISK 289
Cdd:TIGR03789 129 QQLLEELALGMNVQFRTGSSDIEPHFQPQLDEV-ATLMKQSP-ELKLDLSGYADRRGDSQYNQALSEQRVLEVRSYLIKQ 206

                          90
                  ....*....|....*...
gi 490519937  290 GIPSNKISARGMGESNPV 307
Cdd:TIGR03789 207 GVDEARLTTQAFGESAPL 224
 
Name Accession Description Interval E-value
PRK10808 PRK10808
outer membrane protein A; Reviewed
 1-347 0e+00

outer membrane protein A; Reviewed


Pssm-ID: 236764 [Multi-domain]  Cd Length: 351  Bit Score: 715.70  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYAGGKLGWSQFHDTGF--IPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDW 78
Cdd:PRK10808   1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGGKLGWSQYHDTGYgfINNNGPTHKNQLGAGAFGGYQANPYLGFEMGYDW 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  79 LGRMPYKGDTVNGAFKAQGVQLTAKLGYPVTDDLDVYTRLGGMVWRADSSSNIGGD---DHDTGVSPVFAGGVEWAMTRD 155
Cdd:PRK10808  81 LGRMPYKGDVNNGAFKAQGVQLTAKLGYPITDDLDVYTRLGGMVWRADTKSNVPGArgkDHDTGVSPVFAGGVEYAITKN 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 156 IATRLEYQWVNNIGDAQTVGARPDNGMLSVGVSYRFGQQEdAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEG 235
Cdd:PRK10808 161 WATRLEYQWTNNIGDADTVGARPDNGMLSVGVSYRFGQEE-AAPVVAPAPAPAPVVQTKHFTLKSDVLFNFNKATLKPEG 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 236 QQALDQLYSQLSNLDPKDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARGMGESNPVTGNTCDNV 315
Cdd:PRK10808 240 QQALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSEKRAQSVVDYLVSKGIPADKISARGMGKSNPVTGNTCDNV 319

                        330       340       350
                 ....*....|....*....|....*....|..
gi 490519937 316 KPRAALIECLGPDRRVEIEVKGVKDVVTQPQA 347
Cdd:PRK10808 320 KPRAALIDCLAPDRRVEIEVKGIKDVVTQPQA 351
OmpA_membrane pfam01389
OmpA-like transmembrane domain; The structure of OmpA transmembrane domain shows that it ...
 23-195 1.52e-94

OmpA-like transmembrane domain; The structure of OmpA transmembrane domain shows that it consists of an eight stranded beta barrel. This family includes some other distantly related outer membrane proteins with low scores.


Pssm-ID: 396112  Cd Length: 177  Bit Score: 278.94  E-value: 1.52e-94
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   23 PKDNTWYAGGKLGWSQFHDTGFIPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDTVNGAFKAQGVQLTA 102
Cdd:pfam01389   1 PAANTWYTGAKAGWASFHDTGNIEGNGPTHENSLTAGAFGGYQINNYLAAELGYDYLGRMPYKGKGKNNAHKAQGVTLSL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  103 KLGYPVTDDLDVYTRLGGMVWRADSSSNIG----GDDHDTGVSPVFAGGVEWAMTRDIATRLEYQWVNNIGDAQTVGARP 178
Cdd:pfam01389  81 KLSYPLTDDLDVYGKVGGALVRADYKFYEDangkTGNHDTGVSPLFALGVEYAITPELAVRLEYQYLNNIGDLHKQGKRP 160

                         170
                  ....*....|....*..
gi 490519937  179 DNGMLSVGVSYRFGQQE 195
Cdd:pfam01389 161 DNGSASLGISYRFGQGE 177
OmpA_C-like cd07185
Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; ...
 221-335 2.43e-38

Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.


Pssm-ID: 143586 [Multi-domain]  Cd Length: 106  Bit Score: 132.29  E-value: 2.43e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 221 DVLFNFNKATLKPEGQQALDQLYSQLSNLDpkDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARG 300
Cdd:cd07185    3 TIYFDFGSAELTPEAKPLLDKLAEVLKKNP--DAKIRIEGHTDSRGSDAYNQELSERRAEAVADYLVSKGVDASRITAVG 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490519937 301 MGESNPVTGNtcdnvkpraALIECLGPDRRVEIEV 335
Cdd:cd07185   81 YGESRPIASN---------DTEEGRAKNRRVEIVI 106
OmpA COG2885
Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall ...
 39-337 9.45e-38

Outer membrane protein OmpA and related peptidoglycan-associated (lipo)proteins [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442131 [Multi-domain]  Cd Length: 294  Bit Score: 136.84  E-value: 9.45e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  39 FHDTGFIPNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDTVNGAFKAQGVQLTAKLGYPVTDDLDVYTRL 118
Cdd:COG2885    2 SEAALGASALAIDAAGGLLSGAALLLALLGVLGSAGGLLSLADDLAEASAGAAGGAAAGAEAGGLSAGLELLDAGSLSAT 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 119 GGMVWRADSSSNIGGDDHDTGVSPVFAGGVEWAMTRDIATRLEYQWVNNIGDAQTVGARPDNGMLSV----GVSYRFGQQ 194
Cdd:COG2885   82 AAAGAAALLVLLAALGALGAGLAALLLAIAAAASAAAADALALAAGAAAALGALGASAAAAAAALAAakalGDSAAAALD 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 195 EDAAPVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLdpKDGSVVVLGFTDRIGSDAYNQGL 274
Cdd:COG2885  162 AAAKAEAAAAAAALLPAAVAEVVLLSNVYFDFDSAELTPEAKAALDELAALLKEN--PDLRIEIEGHTDSRGSDAYNLAL 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490519937 275 SEKRAQSVVDYLISKGIPSNKISARGMGESNPVtgNTCDNVKPRAAlieclgpDRRVEIEVKG 337
Cdd:COG2885  240 SERRAEAVKDYLVSKGIPASRITAVGYGESRPV--ASNDTEEGRAK-------NRRVEIVVLK 293
OmpA pfam00691
OmpA family; The Pfam entry also includes MotB and related proteins which are not included in ...
 224-318 8.47e-27

OmpA family; The Pfam entry also includes MotB and related proteins which are not included in the Prosite family.


Pssm-ID: 425825 [Multi-domain]  Cd Length: 95  Bit Score: 101.67  E-value: 8.47e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  224 FNFNKATLKPEGQQALDQLYSQLSNLDPKDgSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARGMGE 303
Cdd:pfam00691   1 FDPGSSQLTPKAKATLDEIADLLKFPELKN-TITIEGHTDTVGSAAYNWELSQRRAEAVRRYLVNFGVPPSRISVVGYGA 79

                          90
                  ....*....|....*
gi 490519937  304 SNPVTGNTCDNVKPR 318
Cdd:pfam00691  80 TKPITDNKTPEGRAR 94
MotB COG1360
Flagellar motor protein MotB [Cell motility];
216-333 2.71e-21

Flagellar motor protein MotB [Cell motility];


Pssm-ID: 440971 [Multi-domain]  Cd Length: 174  Bit Score: 89.52  E-value: 2.71e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 216 FTLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDpkdGSVVVLGFTDR--IGSDAY--NQGLSEKRAQSVVDYLISKGI 291
Cdd:COG1360   55 IEIQDRVLFDSGSAELTPEGRELLDKIAAVLAEVP---NRIRVEGHTDNvpISTARFpsNWELSAARAAAVVRYLIEGGV 131

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 490519937 292 PSNKISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:COG1360  132 PPERLSAVGYGDTRPLAPN--DTPEGRAR-------NRRVEI 164
OMP_b-brl pfam13505
Outer membrane protein beta-barrel domain; This domain is found in a wide range of outer ...
 7-191 3.51e-21

Outer membrane protein beta-barrel domain; This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.


Pssm-ID: 463903 [Multi-domain]  Cd Length: 175  Bit Score: 89.00  E-value: 3.51e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937    7 AIAVALAGFATVAQAAPKDNTWYAGGKLGWSQFHdtgfipNDGPTHESQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKG 86
Cdd:pfam13505   1 AALLLLAAFSAAAAAAEEFGGFYVGGGLGNANFS------FDGDGTDSGGGFGVGAGYDFNDYLGVEGELGYGSDDDYSG 74

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937   87 DTVNGA-FKAQGVQLTAKLGYPVTDDLDVYTRLGGMVWRADSSSNiGGDDHDTGVSPVFAGGVEWAMTRDIATRLEYqwv 165
Cdd:pfam13505  75 GGNTDAnIRSLSIGVNLGYRFPLSDSLLPYGGAGYGYSKLEGDYN-GVSDSGTDFGFGYGAGVEYALTDHLAVRAEY--- 150

                         170       180
                  ....*....|....*....|....*.
gi 490519937  166 nNIGDAQTVGARPDNGMLSVGVSYRF 191
Cdd:pfam13505 151 -RYTDIKSGGDDLKNNTFQLGVGYRF 175
LomR COG3637
Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];
56-191 2.21e-15

Opacity protein LomR and related surface antigens [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442854 [Multi-domain]  Cd Length: 154  Bit Score: 72.70  E-value: 2.21e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  56 LGAGAFGGYQV---NPYVGFEMGYDWLGrmpYKGD--TVNGAFKAQGVQLTAKLGYPVTDDLDVYTRLGGMVWRADSSSN 130
Cdd:COG3637    9 LAAGVQAGYNFqfdNFVLGVEGDYSYSD---IDGDssGTTGSGDLDYLSLRARAGYDFNDRFLPYATAGVAYARVKVTGN 85

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490519937 131 IG----GDDHDTGVSPVFAGGVEWAMTRDIATRLEYQWVN----NIGDAQTVGARPDNGMLSVGVSYRF 191
Cdd:COG3637   86 TGsgtsGSDSDTRFGWTVGAGVEYALTDNWSLRLEYRYTDlgdaDFDGGGSVDVDLDSHTVRVGLNYRF 154
PRK09039 PRK09039
peptidoglycan -binding protein;
216-333 2.32e-14

peptidoglycan -binding protein;


Pssm-ID: 181619 [Multi-domain]  Cd Length: 343  Bit Score: 73.08  E-value: 2.32e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 216 FTLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLD---PKDGSVV--VLGFTDRI---GSDAY--NQGLSEKRAQSVVDY 285
Cdd:PRK09039 220 FVFQSEVLFPTGSAELNPEGQAEIAKLAAALIELAkeiPPEINWVlrVDGHTDNVplsGTGRFrdNWELSSARAISVVKF 299

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*....
gi 490519937 286 LISKGIPSNKISARGMGESNPV-TGNTCDnvkPRAAlieclgpDRRVEI 333
Cdd:PRK09039 300 LIALGVPADRLAAAGFGEFQPLdPGDTPE---ARAR-------NRRIEL 338
PRK10510 PRK10510
OmpA family lipoprotein;
220-333 8.96e-14

OmpA family lipoprotein;


Pssm-ID: 182507 [Multi-domain]  Cd Length: 219  Bit Score: 69.52  E-value: 8.96e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 220 SDVLFNFNKATLKPEGQQALDQLYSQLSNLDPKdgSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISAR 299
Cdd:PRK10510 112 NNVTFDSSSATLKPAGANTLTGVAMVLKEYPKT--AVNVVGYTDSTGSHDLNMRLSQQRADSVASALITQGVDASRIRTQ 189

                         90       100       110
                 ....*....|....*....|....*....|....
gi 490519937 300 GMGESNPVTGNTCDNVKPRaalieclgpDRRVEI 333
Cdd:PRK10510 190 GMGPANPIASNSTAEGKAQ---------NRRVEI 214
pdsO TIGR03789
proteobacterial sortase system peptidoglycan-associated protein; A newly defined histidine ...
 210-307 2.79e-12

proteobacterial sortase system peptidoglycan-associated protein; A newly defined histidine kinase (TIGR03785) and response regulator (TIGR03787) gene pair occurs exclusively in Proteobacteria, mostly of marine origin, nearly all of which contain a subfamily 6 sortase (TIGR03784) and its single dedicated target protein (TIGR03788) adjacent to to the sortase. This protein family shows up in only in those species with the histidine kinase/response regulator gene pair, and often adjacent to that pair. It belongs to the pfam00691 domain family, which is the peptidoglycan-associated region of flagellar motor protein MotB, OmpA (whose N-terminal region forms an outer membrane beta barrel), and peptidoglycan-associated lipoprotein Pal. Its function is unknown. We assign the gene symbol pdsO, for Proteobacterial Dedicated Sortase system OmpA family protein. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274783 [Multi-domain]  Cd Length: 243  Bit Score: 65.60  E-value: 2.79e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  210 EVQTKHFTLKSDVLFNFNKATLKPEGQQALDQLySQLSNLDPkDGSVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISK 289
Cdd:TIGR03789 129 QQLLEELALGMNVQFRTGSSDIEPHFQPQLDEV-ATLMKQSP-ELKLDLSGYADRRGDSQYNQALSEQRVLEVRSYLIKQ 206

                          90
                  ....*....|....*...
gi 490519937  290 GIPSNKISARGMGESNPV 307
Cdd:TIGR03789 207 GVDEARLTTQAFGESAPL 224
PRK09967 PRK09967
OmpA family protein;
218-333 3.29e-12

OmpA family protein;


Pssm-ID: 182172 [Multi-domain]  Cd Length: 160  Bit Score: 63.84  E-value: 3.29e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 218 LKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDPKDGSVVvlGFTDRIGSDAYNQGLSEKRAQSVVD-YLISKGIPSNKI 296
Cdd:PRK09967  50 LSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMD--GHTDNYGEDSYNEGLSLKRANVVADaWAMGGQIPRSNL 127

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 490519937 297 SARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:PRK09967 128 TTQGLGKKYPIASN--KTAQGRAE-------NRRVAV 155
PRK09040 PRK09040
hypothetical protein; Provisional
 222-333 8.04e-12

hypothetical protein; Provisional


Pssm-ID: 181620 [Multi-domain]  Cd Length: 214  Bit Score: 63.88  E-value: 8.04e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 222 VLFNFNKATLKPEGQQALDQLYSQLSN-LDPKDGSVVVLGFTD----RIGSDAY--NQGLSEKRAQSVVDYLISKGIPSN 294
Cdd:PRK09040  90 VLFALNSDQLQPEGRELLKSLAGPLAAyLRARDEILMVSGFTDdqpvRAGNRRFadNWELSAQRALTVTRALIDAGVPAS 169

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 490519937 295 KISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:PRK09040 170 SVFAAAFGSEQPVASN--ADDEGRAK-------NRRVEI 199
PRK08126 PRK08126
hypothetical protein; Provisional
 217-335 2.12e-11

hypothetical protein; Provisional


Pssm-ID: 236157 [Multi-domain]  Cd Length: 432  Bit Score: 64.71  E-value: 2.12e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 217 TLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDpkdGSVVVLGFTD----RIGSDAYNQGLSEKRAQSVVDYLISKGIP 292
Cdd:PRK08126 320 VFRGDAMFVPGQATVNPAMGPLIAKIAREIARVG---GKVTVTGHTDnqpiRSAQFASNLVLSEKRAAQVAQMLQSAGVP 396

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 490519937 293 SNKISARGMGESNPVTgntcDNVKP--RAAlieclgpDRRVEIEV 335
Cdd:PRK08126 397 ASRLEAVGKGDAQPVA----DNRTPqgRAQ-------NRRVEITV 430
PRK09038 PRK09038
flagellar motor protein MotD; Reviewed
 218-333 4.59e-10

flagellar motor protein MotD; Reviewed


Pssm-ID: 181618 [Multi-domain]  Cd Length: 281  Bit Score: 59.64  E-value: 4.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 218 LKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDpkdGSVVVLGFTDR--IGSDAY--NQGLSEKRAQSVVDYLISKGIPS 293
Cdd:PRK09038 131 INSSLLFGSGDAMLSDQAFAILEKVAEVLKPAP---NPIHVEGFTDNvpIATAQFpsNWELSAARAASVVRLLADDGVAP 207

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 490519937 294 NKISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:PRK09038 208 SRLAAVGYGEFQPVADN--DTAEGRAR-------NRRVVL 238
PRK07033 PRK07033
DotU family type VI secretion system protein;
217-335 5.36e-09

DotU family type VI secretion system protein;


Pssm-ID: 180801 [Multi-domain]  Cd Length: 427  Bit Score: 56.98  E-value: 5.36e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 217 TLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDpkdGSVVVLGFTD----RIGSDAYNQGLSEKRAQSVVDYLISKGIP 292
Cdd:PRK07033 311 TLRGDGLFASASTSVRDRYQPVLARVADALNQVK---GNVLVTGYSDnvpiRTARFPSNWELSQARAQAVRALLAARLGQ 387

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|...
gi 490519937 293 SNKISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEIEV 335
Cdd:PRK07033 388 PERVTAEGRGDSDPVAPN--DSAENRAR-------NRRVEITL 421
motB PRK08457
flagellar motor protein MotB; Reviewed
 216-333 9.69e-09

flagellar motor protein MotB; Reviewed


Pssm-ID: 181435 [Multi-domain]  Cd Length: 257  Bit Score: 55.49  E-value: 9.69e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 216 FTLKSDVLFNFNKATLKPEGQQALDQLYSQLSNLDPKDGSVVVLGFTD---RIGS---DAYNqgLSEKRAQSVVDYLISK 289
Cdd:PRK08457 118 LKLPSKLLFENGSAEIINADMMDYLKRIAKIITKLPKQVKINVRGYTDnspLNKSrykDHYE--LAAARAYNVMKVLIQY 195

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 490519937 290 GIPSNKISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:PRK08457 196 GINPNRLSFSSYGSNNPIAPN--DSLENRLK-------NNRVEI 230
PRK10802 PRK10802
peptidoglycan-associated lipoprotein Pal;
222-306 4.83e-06

peptidoglycan-associated lipoprotein Pal;


Pssm-ID: 182744 [Multi-domain]  Cd Length: 173  Bit Score: 46.40  E-value: 4.83e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 222 VLFNFNKATLKPEGQQALDQLYSQL-SNLDPKdgsVVVLGFTDRIGSDAYNQGLSEKRAQSVVDYLISKGIPSNKISARG 300
Cdd:PRK10802  71 VYFDLDKYDIRSDFAQMLDAHANFLrSNPSYK---VTVEGHADERGTPEYNIALGERRANAVKMYLQGKGVSADQISIVS 147


                 ....*.
gi 490519937 301 MGESNP 306
Cdd:PRK10802 148 YGKEKP 153
OmpC COG3203
Outer membrane porin OmpC/OmpF/PhoE [Cell wall/membrane/envelope biogenesis];
11-191 4.96e-05

Outer membrane porin OmpC/OmpF/PhoE [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442436 [Multi-domain]  Cd Length: 336  Bit Score: 44.61  E-value: 4.96e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  11 ALAGFATVAQAAPKDNTW-----YAGGKLGWS---QFHDTGFIPNDGPTHESQLGAGAfgGYQVNP-YVGFemGYdwlGR 81
Cdd:COG3203  164 AQYSFGEDAGSSSNGRGYgagltYANGPLSLGaayQQSNDAQGATAGGDDADAWGLGA--SYDFGNlKLAA--GY---GQ 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937  82 MPYKGDTVNGAFKAQGVQLTAklGYPVTDDLdvytRLGGMVWRADSSSNIGGDDHDTgvspvFAGGVEWAMTRDIATRLE 161
Cdd:COG3203  237 TKNDDAGGAGNAKADGYELGA--SYPFGPAL----TLSASYGYTDAKDGADDDDANQ-----YALGADYALSKRTSLYAE 305

                        170       180       190
                 ....*....|....*....|....*....|.
gi 490519937 162 YQWVNNIGDAQTVGARPDNG-MLSVGVSYRF 191
Cdd:COG3203  306 YGYNDNDGNANFTAAAGDTDdGVAVGLRHKF 336
PRK14693 PRK14693
hypothetical protein; Provisional
 216-345 6.16e-05

hypothetical protein; Provisional


Pssm-ID: 173156 [Multi-domain]  Cd Length: 552  Bit Score: 44.75  E-value: 6.16e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 216 FTLKSDVLFNFNKATLKPEGQQALDQLYSQLSnldPKDGSVVVLGFTD----RIGSDAYNQGLSEKRAQSVVDYLISKGI 291
Cdd:PRK14693 368 LVFKSDGAFDVGKANVRADFMHNIERLGLAFA---PWPGDLEVIGHTDsrpiRTSEFPDNQALSEARARNVADELRKTAL 444

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490519937 292 P----------SNKISARGMGESNPVtgntcDNVKPRAALIEclgpDRRVEIEVKGVKDVVTQP 345
Cdd:PRK14693 445 PggarapenavQRNIEYSGRGDAQPI-----DTAKTAAAYER----NRRVDVLWKVIPDGAQQS 499
motB PRK07734
flagellar motor protein MotB; Reviewed
 217-333 6.30e-04

flagellar motor protein MotB; Reviewed


Pssm-ID: 236080 [Multi-domain]  Cd Length: 259  Bit Score: 40.88  E-value: 6.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490519937 217 TLKSDVLFNFNKATLKPEGQqaldQLYSQLSNL----DPKDgsVVVLGFTDRI---GSD-AYNQGLSEKRAQSVVDYLI- 287
Cdd:PRK07734 139 TILDNILFDSGKADVRLEDL----PLAKEISNLlvsnPPRN--ITISGHTDNVpiaNAQfASNWELSVMRAVNFMQVLLe 212

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 490519937 288 SKGIPSNKISARGMGESNPVTGNtcDNVKPRAAlieclgpDRRVEI 333
Cdd:PRK07734 213 NKELDPEKFSAKGYGEYKPIASN--DTAEGRAK-------NRRVEV 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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