|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
2-696 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1125.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 2 ALTAAQKSQIAAWYKALQQQIPDFIPRAPQRQMIAEVAKTLGGDE---GRHLAIEAPTGVGKTLSYLIPGIAIAREEQKT 78
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 79 LVVSTANVALQDQIFSKDLPLLRKIIP-ELRFTAAFGRGRYVCPRNLAALSTDSASQGDLLAFLDDELTPNSKEEQQRCA 157
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 158 KLKADLDSYKWDGLRDHTDQAIDDNLWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAALE--SES 235
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 236 VLPEPKHLLLVLDEGHHLPDVARDALEMSADI--SAPWTRLQLDLFCKLVATCLEqfrpktvPPLSTPERLNNHCEEVYE 313
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIME-------PPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 314 LVASMNRIVGLLLPPG-EESEFRFPMGELPQEVMEICERLAKLTENLRGLAELFLNDLSE--KTGSHDIVRLHRVLLQMN 390
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 391 RALGHFEAQSKLWRLAS-LAHASGAPVSKWVTRETREGQPHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFA 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 470 RLQEMSGLRDKAGDRFVTLDSPFNHIEQGKIVIPRLRHEPlmEHEEAHLAEMAAYFRAEYKKgeHKGMLVLFASNRAMQT 549
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEK--HKGSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 550 FLSFVP-DLRLGLLVQGDQPRYRLVELHRKKIEQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGE 628
Cdd:PRK11747 550 VADLLPrDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490520429 629 WLKSLNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALPVFAIEQPE 696
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
13-706 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 559.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 13 AWYKALQQQIPDFIPRAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQI 92
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 93 FSKDLPLLRKIIP-ELRFTAAFGRGRYVCPRNLAALSTDSASQGDLLAFLddeltpnskeeqqrcaKLKADLDSYKWDGL 171
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLDDEELLL----------------ARILAWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 172 RDHTDQAIDDNLWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAALES-ESVLPEpkHLLLVLDEG 250
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 251 HHLPDVARDALemSADISAPWTRLQLDLFCKLVAtcleqfRPKTVPPLSTPERLNNHCEEVYELVasmnrivglllppGE 330
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 331 ESEFRFPMGELPQEvmeiCERLAKLTENLRGLAELFLNDLSEKTGSH-DIVRLHRVLLQMNRALGHFeaqsklwrlasLA 409
Cdd:COG1199 280 EEELRLALGELPDE----PEELLEALDALRDALEALAEALEEELERLaELDALLERLEELLFALARF-----------LR 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 410 HASGAPVSKWVTRETRegqpHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFARLQEMSGLRDKAgdRFVTLD 489
Cdd:COG1199 345 IAEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLP 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 490 SPFNHIEQGKIVIPRLRHEPlmEHEEAHLAEMAAYFRAEYKKgEHKGMLVLFASNRAMQTFLSFVPD-LRLGLLVQGDQP 568
Cdd:COG1199 419 SPFDYENQALLYVPRDLPRP--SDRDGYLEAIAEAIAELLEA-SGGNTLVLFTSYRALEQVAELLRErLDIPVLVQGDGS 495
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 569 RYRLVELHRkkieQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAASF 648
Cdd:COG1199 496 REALLERFR----EGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVI 571
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 490520429 649 SLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALPVFAIEQPEAPEALIKKAP 706
Cdd:COG1199 572 KLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEELRAFLERLD 629
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
28-688 |
2.57e-47 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 180.38 E-value: 2.57e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 28 RAPQRQMIAEVAKTLGGDEgrHLAIEAPTGVGKTLSYLIPGIAIAREEqKTLVVSTANVALQDQIFSKDLPLLRKIIP-E 106
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAITE-KPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 107 LRFTAAFGRGRYvcprnlaaLSTDSASQgdllaflddELTPNSKEEQQRCAKLK----------ADLDSYKWDGLRDHtd 176
Cdd:TIGR01407 324 INAALIKGKSNY--------LSLGKFSQ---------ILKDNTDNYEFNIFKMQvlvwltetetGDLDELNLKGGNKM-- 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 177 qaiddnLWSRLSTDKAscLNRNCHYYRECPFFVARREIQEAEVVVANHA-LVMAALESESVLPEPKhlLLVLDEGHHLPD 255
Cdd:TIGR01407 385 ------FFAQVRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAyLITRLVDNPELFPSFR--DLIIDEAHHLPD 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 256 VARDALEMSADISApwTRLQLDLFCKlvatcleqfrpktvpplSTPERLnnhceevyelvasMNRIVGLLLPPGEESEFR 335
Cdd:TIGR01407 455 IAENQLQEELDYAD--IKYQIDLIGK-----------------GENEQL-------------LKRIQQLEKQEILEKLFD 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 336 FPMGELPQEVMEICERLAKLTENLRGLAelflndlsektgshdivrlHRVLLQMNRALGHFEaqSKLWRLASLAHASGap 415
Cdd:TIGR01407 503 FETKDILKDLQAILDKLNKLLQIFSELS-------------------HKTVDQLRKFDLALK--DDFKNIEQSLKEGH-- 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 416 vSKWVTRETREGQPHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFARLQEMSGLRDKagdRFVTLD-SPFNH 494
Cdd:TIGR01407 560 -TSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEpTPLNY 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 495 IEQGKIVIPrlrhEPLMEHEEAHLAEMAAYFRA---EYKKGEHKGMLVLFASNRAMQTFLSFVPDLRLG----LLVQG-D 566
Cdd:TIGR01407 636 AENQRVLIP----TDAPAIQNKSLEEYAQEIASyiiEITAITSPKILVLFTSYEMLHMVYDMLNELPEFegyeVLAQGiN 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 567 QPRYRLVelhrKKIEQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAA 646
Cdd:TIGR01407 712 GSRAKIK----KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDYVLPMA 787
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 490520429 647 SFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALP 688
Cdd:TIGR01407 788 IIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
534-690 |
2.50e-41 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 148.48 E-value: 2.50e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 534 HKGMLVLFASNRAMQTFLSFVPDLRLG----LLVQ-GDQPRYRLVELHRKKieqGEASVLVGLQ--SFAEGLDLKGELLS 606
Cdd:pfam13307 8 PGGVLVFFPSYSYLEKVAERLKESGLEkgieIFVQpGEGSREKLLEEFKKK---GKGAVLFGVCggSFSEGIDFPGDLLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 607 QVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDA 686
Cdd:pfam13307 85 AVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLPKW 164
|
....
gi 490520429 687 LPVF 690
Cdd:pfam13307 165 LPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
545-676 |
4.45e-26 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 104.28 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 545 RAMQTFLSFVPDLRLG-----LLVQGDQPRYR-LVELHRKKIEQGEASVLVGLQS--FAEGLDLKGELLSQVHIHKIAFP 616
Cdd:smart00491 2 RYLEQVVEYWKENGILeinkpVFIEGKDSGETeELLEKYSAACEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPFP 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490520429 617 PVDSPVVVTEGEWLKS-LNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLT 676
Cdd:smart00491 82 NPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
595-673 |
5.50e-04 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 41.05 E-value: 5.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 595 AEGLDLKGELLSQVHIHKIAFPPVDSPVVVtegewLKSLNRYPFEVQSLPAASFSLIQQ--------VGRLIRSHSCWGE 666
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 490520429 667 VVIYDRR 673
Cdd:cd18788 152 IVLLDKR 158
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| dinG |
PRK11747 |
ATP-dependent DNA helicase DinG; Provisional |
2-696 |
0e+00 |
|
ATP-dependent DNA helicase DinG; Provisional
Pssm-ID: 236966 [Multi-domain] Cd Length: 697 Bit Score: 1125.30 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 2 ALTAAQKSQIAAWYKALQQQIPDFIPRAPQRQMIAEVAKTLGGDE---GRHLAIEAPTGVGKTLSYLIPGIAIAREEQKT 78
Cdd:PRK11747 1 MLTDALKAQIRQAYKALQEQLPGFIPRAGQRQMIAEVAKTLAGEYlkdGRILVIEAGTGVGKTLSYLLAGIPIARAEKKK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 79 LVVSTANVALQDQIFSKDLPLLRKIIP-ELRFTAAFGRGRYVCPRNLAALSTDSASQGDLLAFLDDELTPNSKEEQQRCA 157
Cdd:PRK11747 81 LVISTATVALQEQLVSKDLPLLLKISGlDFKFTLAKGRGRYVCPRKLAALASDEGTQQDLLLFLDDELTPPDEEEQKLLA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 158 KLKADLDSYKWDGLRDHTDQAIDDNLWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAALE--SES 235
Cdd:PRK11747 161 RLAKALATGKWDGDRDHWPEPIDDSLWQRITTDKHSCLGRNCPYFRECPFFKARREIDEADVVVANHDLVLADLElgGGV 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 236 VLPEPKHLLLVLDEGHHLPDVARDALEMSADI--SAPWTRLQLDLFCKLVATCLEqfrpktvPPLSTPERLNNHCEEVYE 313
Cdd:PRK11747 241 VLPDPENLLYVLDEGHHLPDVARDHFAASAELkgTADWLEKLLKLLTKLVALIME-------PPLALPERLNAHCEELRE 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 314 LVASMNRIVGLLLPPG-EESEFRFPMGELPQEVMEICERLAKLTENLRGLAELFLNDLSE--KTGSHDIVRLHRVLLQMN 390
Cdd:PRK11747 314 LLASLNQILNLFLPAGgEEARYRFEMGELPEELLELAERLAKLTEKLLGLLEKLLNDLSEamKTGKIDIVRLERLLLELG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 391 RALGHFEAQSKLWRLAS-LAHASGAPVSKWVTRETREGQPHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFA 469
Cdd:PRK11747 394 RALGRLEALSKLWRLAAkEDQESGAPMARWITREERDGQGDYLFHASPIRVGDQLERLLWSRAPGAVLTSATLRSLNSFD 473
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 470 RLQEMSGLRDKAGDRFVTLDSPFNHIEQGKIVIPRLRHEPlmEHEEAHLAEMAAYFRAEYKKgeHKGMLVLFASNRAMQT 549
Cdd:PRK11747 474 RFQEQSGLPEKDGDRFLALPSPFDYPNQGKLVIPKMRAEP--DNEEAHTAEMAEFLPELLEK--HKGSLVLFASRRQMQK 549
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 550 FLSFVP-DLRLGLLVQGDQPRYRLVELHRKKIEQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGE 628
Cdd:PRK11747 550 VADLLPrDLRLMLLVQGDQPRQRLLEKHKKRVDEGEGSVLFGLQSFAEGLDLPGDYLTQVIITKIPFAVPDSPVEATLAE 629
|
650 660 670 680 690 700
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490520429 629 WLKSLNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALPVFAIEQPE 696
Cdd:PRK11747 630 WLKSRGGNPFMEISVPDASFKLIQAVGRLIRSEQDRGRVTILDRRLLTKRYGKRLLDALPPFKREIEE 697
|
|
| DinG |
COG1199 |
Rad3-related DNA helicase DinG [Replication, recombination and repair]; |
13-706 |
0e+00 |
|
Rad3-related DNA helicase DinG [Replication, recombination and repair];
Pssm-ID: 440812 [Multi-domain] Cd Length: 629 Bit Score: 559.93 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 13 AWYKALQQQIPDFIPRAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQI 92
Cdd:COG1199 1 ADDGLLALAFPGFEPRPGQREMAEAVARAL--AEGRHLLIEAGTGTGKTLAYLVPALLAARETGKKVVISTATKALQEQL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 93 FSKDLPLLRKIIP-ELRFTAAFGRGRYVCPRNLAALSTDSASQGDLLAFLddeltpnskeeqqrcaKLKADLDSYKWDGL 171
Cdd:COG1199 79 VEKDLPLLRKALGlPLRVALLKGRSNYLCLRRLEQALQEGDDLDDEELLL----------------ARILAWASETWTGD 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 172 RDHTDQAIDDNLWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAALES-ESVLPEpkHLLLVLDEG 250
Cdd:COG1199 143 RDELPLPEDDELWRQVTSDADNCLGRRCPYYGVCPYELARRLAREADVVVVNHHLLFADLALgEELLPE--DDVLIIDEA 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 251 HHLPDVARDALemSADISAPWTRLQLDLFCKLVAtcleqfRPKTVPPLSTPERLNNHCEEVYELVasmnrivglllppGE 330
Cdd:COG1199 221 HNLPDRARDMF--SAELSSRSLLRLLRELRKLGL------RPGLKKLLDLLERLREALDDLFLAL-------------EE 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 331 ESEFRFPMGELPQEvmeiCERLAKLTENLRGLAELFLNDLSEKTGSH-DIVRLHRVLLQMNRALGHFeaqsklwrlasLA 409
Cdd:COG1199 280 EEELRLALGELPDE----PEELLEALDALRDALEALAEALEEELERLaELDALLERLEELLFALARF-----------LR 344
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 410 HASGAPVSKWVTRETRegqpHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFARLQEMSGLRDKAgdRFVTLD 489
Cdd:COG1199 345 IAEDEGYVRWLEREGG----DVRLHAAPLDPADLLRELLFSRARSVVLTSATLSVGGPFDYFARRLGLDEDA--RTLSLP 418
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 490 SPFNHIEQGKIVIPRLRHEPlmEHEEAHLAEMAAYFRAEYKKgEHKGMLVLFASNRAMQTFLSFVPD-LRLGLLVQGDQP 568
Cdd:COG1199 419 SPFDYENQALLYVPRDLPRP--SDRDGYLEAIAEAIAELLEA-SGGNTLVLFTSYRALEQVAELLRErLDIPVLVQGDGS 495
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 569 RYRLVELHRkkieQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAASF 648
Cdd:COG1199 496 REALLERFR----EGGNSVLVGTGSFWEGVDLPGDALSLVIIVKLPFPPPDDPVLEARREALEARGGNGFMYAYLPPAVI 571
|
650 660 670 680 690
....*....|....*....|....*....|....*....|....*....|....*...
gi 490520429 649 SLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALPVFAIEQPEAPEALIKKAP 706
Cdd:COG1199 572 KLKQGAGRLIRSEEDRGVVVLLDRRLLTKRYGKRFLDSLPPFRRTRPEELRAFLERLD 629
|
|
| PRK08074 |
PRK08074 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
15-688 |
7.19e-71 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 236148 [Multi-domain] Cd Length: 928 Bit Score: 249.10 E-value: 7.19e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 15 YKALQQQIPDFIPRAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIFS 94
Cdd:PRK08074 246 EEKLSLAMPKYEKREGQQEMMKEVYTAL--RDSEHALIEAGTGTGKSLAYLLPAAYFAKKKEEPVVISTYTIQLQQQLLE 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 95 KDLPLLRKIIP-ELRFTAAFGRGRYVCPRNLAAlstdsasqgdllaFLDDEltpnskEEQQRCAKLKADLdsYKWdgLRD 173
Cdd:PRK08074 324 KDIPLLQKIFPfPVEAALLKGRSHYLCLRKFEQ-------------ALQEE------DDNYDVALTKAQL--LVW--LTE 380
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 174 HTDQAIDD--------NLWSRLSTDKASCLNRNCHYYRECPFFVARREIQEAEVVVANHALVMAALESE-SVLPEPKHLl 244
Cdd:PRK08074 381 TETGDLDElnlpsggkLLWNRIASDGESDGGKQSPWFSRCFYQRAKNRAKFADLVITNHALLLTDLTSEePLLPSYEHI- 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 245 lVLDEGHHLPDVARDALEMSAD---ISAPWTRLQLDLFCKLVATCLEQFRPKTVPPLSTPERLNNHC----EEVYELVAS 317
Cdd:PRK08074 460 -IIDEAHHFEEAASRHLGEQFSymsFQLLLSRLGTLEEDGLLSKLAKLFKKSDQASRSSFRDLDESLkelkFEADELFQM 538
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 318 MNRIVGLLLPPGEESEFRFPM------GELPQEVMEICERLAKLTENLRGLAELFLNDLSEKTGSHDIVrLHRVLLQMNr 391
Cdd:PRK08074 539 LRSFVLKRKKQEQNGRLIYRYntesekGKLWDAITELANRLCYDLRDLLTLLEAQKKELQEKMESESAF-LTGEYAHLI- 616
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 392 ALGHFEAQsklwrLASLAHASGAPVSKWVTRETREGQPHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFARL 471
Cdd:PRK08074 617 DLLEKMAQ-----LLQLLFEEDPDYVTWIEIDAKGAINATRLYAQPVEVAERLADEFFAKKKSVILTSATLTVNGSFDYI 691
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 472 QEMSGLRDKaGDRFVTLDSPFNHIEQGKIVIPRlrHEPLMEH--EEAHLAEMAAYFR--AEYKKGEhkgMLVLFASNR-- 545
Cdd:PRK08074 692 IERLGLEDF-YPRTLQIPSPFSYEEQAKLMIPT--DMPPIKDvpIEEYIEEVAAYIAkiAKATKGR---MLVLFTSYEml 765
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 546 -----AMQTFLSFVPdlrLGLLVQGDQ--PRYRLVelhrKKIEQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPV 618
Cdd:PRK08074 766 kktyyNLKNEEELEG---YVLLAQGVSsgSRARLT----KQFQQFDKAILLGTSSFWEGIDIPGDELSCLVIVRLPFAPP 838
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 619 DSPVVVTEGEWLKSLNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALP 688
Cdd:PRK08074 839 DQPVMEAKSEWAKEQGENPFQELSLPQAVLRFKQGFGRLIRTETDRGTVFVLDRRLTTTSYGKYFLESLP 908
|
|
| dinG_rel |
TIGR01407 |
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of ... |
28-688 |
2.57e-47 |
|
DnaQ family exonuclease/DinG family helicase, putative; This model represents a family of proteins in Gram-positive bacteria. The N-terminal region of about 200 amino acids resembles the epsilon subunit of E. coli DNA polymerase III and the homologous region of the Gram-positive type DNA polymerase III alpha subunit. The epsilon subunit contains an exonuclease domain. The remainder of this protein family resembles a predicted ATP-dependent helicase, the DNA damage-inducible protein DinG of E. coli. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273602 [Multi-domain] Cd Length: 850 Bit Score: 180.38 E-value: 2.57e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 28 RAPQRQMIAEVAKTLGGDEgrHLAIEAPTGVGKTLSYLIPGIAIAREEqKTLVVSTANVALQDQIFSKDLPLLRKIIP-E 106
Cdd:TIGR01407 247 RPEQLKLAELVLDQLTHSE--KSLIEAPTGTGKTLGYLLPALYYAITE-KPVVISTNTKVLQSQLLEKDIPLLNEILNfK 323
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 107 LRFTAAFGRGRYvcprnlaaLSTDSASQgdllaflddELTPNSKEEQQRCAKLK----------ADLDSYKWDGLRDHtd 176
Cdd:TIGR01407 324 INAALIKGKSNY--------LSLGKFSQ---------ILKDNTDNYEFNIFKMQvlvwltetetGDLDELNLKGGNKM-- 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 177 qaiddnLWSRLSTDKAscLNRNCHYYRECPFFVARREIQEAEVVVANHA-LVMAALESESVLPEPKhlLLVLDEGHHLPD 255
Cdd:TIGR01407 385 ------FFAQVRHDGN--LSKKDLFYEVDFYNRAQKNAEQAQILITNHAyLITRLVDNPELFPSFR--DLIIDEAHHLPD 454
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 256 VARDALEMSADISApwTRLQLDLFCKlvatcleqfrpktvpplSTPERLnnhceevyelvasMNRIVGLLLPPGEESEFR 335
Cdd:TIGR01407 455 IAENQLQEELDYAD--IKYQIDLIGK-----------------GENEQL-------------LKRIQQLEKQEILEKLFD 502
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 336 FPMGELPQEVMEICERLAKLTENLRGLAelflndlsektgshdivrlHRVLLQMNRALGHFEaqSKLWRLASLAHASGap 415
Cdd:TIGR01407 503 FETKDILKDLQAILDKLNKLLQIFSELS-------------------HKTVDQLRKFDLALK--DDFKNIEQSLKEGH-- 559
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 416 vSKWVTRETREGQPHIFFHCVGIRVSDQLEKLIWRQVPHVVVTSATLRSLNSFARLQEMSGLRDKagdRFVTLD-SPFNH 494
Cdd:TIGR01407 560 -TSWISIENLQQKSTIRLYIKDYEVGDVLTKRLLPKFKSLIFTSATLKFSHSFESFPQLLGLTDV---HFNTIEpTPLNY 635
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 495 IEQGKIVIPrlrhEPLMEHEEAHLAEMAAYFRA---EYKKGEHKGMLVLFASNRAMQTFLSFVPDLRLG----LLVQG-D 566
Cdd:TIGR01407 636 AENQRVLIP----TDAPAIQNKSLEEYAQEIASyiiEITAITSPKILVLFTSYEMLHMVYDMLNELPEFegyeVLAQGiN 711
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 567 QPRYRLVelhrKKIEQGEASVLVGLQSFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAA 646
Cdd:TIGR01407 712 GSRAKIK----KRFNNGEKAILLGTSSFWEGVDFPGNGLVCLVIPRLPFANPKHPLTKKYWQKLEQEGKNPFYDYVLPMA 787
|
650 660 670 680
....*....|....*....|....*....|....*....|..
gi 490520429 647 SFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALP 688
Cdd:TIGR01407 788 IIRLRQALGRLIRRENDRGSIVILDRRLVGKRYGKRFEKSLP 829
|
|
| Helicase_C_2 |
pfam13307 |
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases. |
534-690 |
2.50e-41 |
|
Helicase C-terminal domain; This domain is found at the C-terminus of DEAD-box helicases.
Pssm-ID: 463840 [Multi-domain] Cd Length: 168 Bit Score: 148.48 E-value: 2.50e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 534 HKGMLVLFASNRAMQTFLSFVPDLRLG----LLVQ-GDQPRYRLVELHRKKieqGEASVLVGLQ--SFAEGLDLKGELLS 606
Cdd:pfam13307 8 PGGVLVFFPSYSYLEKVAERLKESGLEkgieIFVQpGEGSREKLLEEFKKK---GKGAVLFGVCggSFSEGIDFPGDLLR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 607 QVHIHKIAFPPVDSPVVVTEGEWLKSLNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDA 686
Cdd:pfam13307 85 AVIIVGLPFPNPDDPVVEAKREYLDSKGGNPFNEWYLPQAVRAVNQAIGRLIRHENDYGAIVLLDSRFLTKRYGKLLPKW 164
|
....
gi 490520429 687 LPVF 690
Cdd:pfam13307 165 LPPG 168
|
|
| HELICc2 |
smart00491 |
helicase superfamily c-terminal domain; |
545-676 |
4.45e-26 |
|
helicase superfamily c-terminal domain;
Pssm-ID: 214694 [Multi-domain] Cd Length: 142 Bit Score: 104.28 E-value: 4.45e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 545 RAMQTFLSFVPDLRLG-----LLVQGDQPRYR-LVELHRKKIEQGEASVLVGLQS--FAEGLDLKGELLSQVHIHKIAFP 616
Cdd:smart00491 2 RYLEQVVEYWKENGILeinkpVFIEGKDSGETeELLEKYSAACEARGALLLAVARgkVSEGIDFPDDLGRAVIIVGIPFP 81
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490520429 617 PVDSPVVVTEGEWLKS-LNRYPFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLT 676
Cdd:smart00491 82 NPDSPILRARLEYLDEkGGIRPFDEVYLFDAMRALAQAIGRAIRHKNDYGVVVLLDKRYAR 142
|
|
| PRK07246 |
PRK07246 |
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated |
28-706 |
4.94e-17 |
|
bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated
Pssm-ID: 180905 [Multi-domain] Cd Length: 820 Bit Score: 85.51 E-value: 4.94e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 28 RAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSYLIPgiAIAREEQKTLVVSTANVALQDQIFSKDLPLLRKiipel 107
Cdd:PRK07246 247 RPKQESFAKLVGEDF--HDGPASFIEAQTGIGKTYGYLLP--LLAQSDQRQIIVSVPTKILQDQIMAEEVKAIQE----- 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 108 RFTAAFG--RGryvcPRNLAALST--DSASQGD-----------LLAFLDDELTPNSKEEQQRcAKLKADLDSYKWDGLR 172
Cdd:PRK07246 318 VFHIDCHslKG----PQNYLKLDAfyDSLQQNDdnrlvnrykmqLLVWLTETETGDLDEIKQK-QRYAAYFDQLKHDGNL 392
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 173 DHTDQAIDDNLWSRlSTDKAsclnrnchyyrecpffvarreiQEAEVVVANHALVMAALESESVLPEPKhlLLVLDEGHh 252
Cdd:PRK07246 393 SQSSLFYDYDFWKR-SYEKA----------------------KTARLLITNHAYFLTRVQDDKDFARNK--VLVFDEAQ- 446
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 253 lpdvardalemsadisapwtrlqldlfcKLVATcLEQFRPKTVPPLSTPERLNNHceevyeLVASMNRIVGLLLppgeES 332
Cdd:PRK07246 447 ----------------------------KLMLQ-LEQLSRHQLNITSFLQTIQKA------LSGPLPLLQKRLL----ES 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 333 eFRFPMGELpqevmeicerlakltenlrglAELFLNDLSEKTGSHDIVRLHRVLLQMNRALghfeaqsklwrLASLAHAS 412
Cdd:PRK07246 488 -ISFELLQL---------------------SEQFYQGKERQLIHDSLSRLHQYFSELEVAG-----------FQELQAFF 534
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 413 GAPVSKWVTRETREGQphiffHCVGIRVSDQLEKLIWRQ-VPHVVVT---SATLR--------SLNSFARLQEMSGLRDK 480
Cdd:PRK07246 535 ATAEGDYWLESEKQSE-----KRVTYLNSASKAFTHFSQlLPETCKTyfvSATLQisprvslaDLLGFEEYLFHKIEKDK 609
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 481 AGDRFVTLDSPFNHIEQGKiviprlrheplmehEEAHLAEMAAyfRAEYKKGEHKGMLVLFASNRAMQTFLSFVPDLRLG 560
Cdd:PRK07246 610 KQDQLVVVDQDMPLVTETS--------------DEVYAEEIAK--RLEELKQLQQPILVLFNSKKHLLAVSDLLDQWQVS 673
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 561 LLVQ---GDQprYRLvelhRKKIEQGEASVLVGLQSFAEGLDLkgellsqVH----IHKIAFPPVDSPvvvtEGEWLKSL 633
Cdd:PRK07246 674 HLAQeknGTA--YNI----KKRFDRGEQQILLGLGSFWEGVDF-------VQadrmIEVITRLPFDNP----EDPFVKKM 736
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 634 NRY-------PFEVQSLPAASFSLIQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRLLDALpvfaieqpeAPEALIKKAP 706
Cdd:PRK07246 737 NQYllqegknPFYDYFLPMTILRLKQAIGRTMRREDQKSAVLILDRRILTKSYGKQILASL---------AEEFLISQQN 807
|
|
| DEXDc2 |
smart00488 |
DEAD-like helicases superfamily; |
25-268 |
6.14e-09 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214693 [Multi-domain] Cd Length: 289 Bit Score: 57.77 E-value: 6.14e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 25 FIPRAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSyLIPGI---AIAREE-----QKTLVVSTAN----------- 85
Cdd:smart00488 7 YEPYPIQYEFMEELKRVL--DRGKIGILESPTGTGKTLS-LLCLTltwLRSFPEriqkiKLIYLSRTVSeiekrleelrk 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 86 -VALQDQIFSKDLPLLRKIIPELRFTAAFGRGRYVCPRN---LAALSTDSASQGDLLAFLDDELTpNSKEEQQRCAKLKA 161
Cdd:smart00488 84 lMQKVEYESDEESEKQAQLLHELGREKPKVLGLSLTSRKnlcLNPEVRTLKQNGLVVDEVCRSLT-ASKARKYRYENPKV 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 162 DLDSYKwdglrDHTDQA--IDDNLWSRLSTDKASCLNRNChyyRECPFFVARREIQEAEVVVANHALVMAALESESVLPE 239
Cdd:smart00488 163 ERCPFY-----ENTEFLlvRDLLPAEVYDIEDLLELGKRL---GGCPYFASRKAIEFANVVVLPYQYLLDPKIRQALSIE 234
|
250 260
....*....|....*....|....*....
gi 490520429 240 PKHLLLVLDEGHHLPDVARDALemSADIS 268
Cdd:smart00488 235 LKDSIVIFDEAHNLDNVCISAL--SSELS 261
|
|
| rad3 |
TIGR00604 |
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are ... |
28-683 |
1.44e-08 |
|
DNA repair helicase (rad3); All proteins in this family for which funcitons are known are DNA-DNA helicases that funciton in the initiation of transcription and nucleotide excision repair as part of the TFIIH complex. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273169 [Multi-domain] Cd Length: 705 Bit Score: 58.19 E-value: 1.44e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 28 RAPQRQMIAEVAKTLggDEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTAnvalqdqifSKDLPLLRKIIPEL 107
Cdd:TIGR00604 12 YPEQRSYMRDLKRSL--DRGDEAILEMPSGTGKTISLLSLILAYQQEKPEVRKIIYA---------SRTHSQLEQATEEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 108 RFTAAFGRGRYVCPRNLAALSTDSASQGDLLAFLDDELTPNSKEEqqRCAKLKADldsykwdglrdhtdqaiddnlWSRL 187
Cdd:TIGR00604 81 RKLMSYRTPRIGEESPVSGLSLASRKNLCLHPEVSKERQGKVVNG--KCIKLTVS---------------------KIKE 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 188 STDKASClNRNCHYYRE------------------------------CPFFVARREIQEAEVVVANHALVMAALESESVL 237
Cdd:TIGR00604 138 QRTEKPN-VESCEFYENfdelrevedlllseimdiedlveygellglCPYFATRKMLPFANIVLLPYQYLLDPKIRSAVS 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 238 PEPKHLLLVLDEGHHLPDVARDALemSADIS----------------------APWTRLQLDLFCKLVATcLEQFRPKTv 295
Cdd:TIGR00604 217 IELKDSIVIFDEAHNLDNVCISSL--SSNLSvrslkrcskeiaeyfekieerkEVDARKLLDELQKLVEG-LKQEDLLT- 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 296 pplSTPERLNNhceEVYELVASMNRIVGLLlppGEESEFRFPMGELpQEVMEICERLAKLTENLRglaelflndLSEKTG 375
Cdd:TIGR00604 293 ---DEDIFLAN---PVLPKEVLPEAVPGNI---RIAEIFLHKLSRY-LEYLKDALKVLGVVSELP---------DAFLEH 353
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 376 SHDIVRLHRVLLQMNRALGHFEAQSKLWRLASLAHASGAPVSKWVTRETREGQPHIF------------FHCVGIRVSDQ 443
Cdd:TIGR00604 354 LKEKTFIDRPLRFCSERLSNLLRELEITHPEDFSALVLLFTFATLVLTYTNGFLEGIepyenktvpnpiLKFMCLDPSIA 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 444 LeKLIWRQVPHVVVTSATLRSLNSFARLqemsglrdkAGDRFVTLDSPfNHI-----------EQGKIVIP-RLRHEplM 511
Cdd:TIGR00604 434 L-KPLFERVRSVILASGTLSPLDAFPRN---------LGFNPVSQDSP-THIlkrenlltlivTRGSDQVPlSSTFE--I 500
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 512 EHEEAHLAEMAAYFrAEYKKGEHKGMLVLFASNRAMQTFLS-----------------FV--PDLRLGLLVqgdqpryrl 572
Cdd:TIGR00604 501 RNDPSLVRNLGELL-VEFSKIIPDGIVVFFPSYSYLENIVStwkemgileniekkkliFVetKDAQETSDA--------- 570
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 573 VELHRKKIEQGEASVLVGLQ--SFAEGLDLKGELLSQVHIHKIAFPPVDSPVVVTEGEWLKSL-----NRYPFEVQSLPA 645
Cdd:TIGR00604 571 LERYKQAVSEGRGAVLLSVAggKVSEGIDFCDDLGRAVIMVGIPYEYTESRILLARLEFLRDQypireNQDFYEFDAMRA 650
|
730 740 750
....*....|....*....|....*....|....*...
gi 490520429 646 ASfsliQQVGRLIRSHSCWGEVVIYDRRLLTKSYGKRL 683
Cdd:TIGR00604 651 VN----QAIGRVIRHKDDYGSIVLLDKRYARSNKRKKL 684
|
|
| DEXDc |
smart00487 |
DEAD-like helicases superfamily; |
25-127 |
4.80e-05 |
|
DEAD-like helicases superfamily;
Pssm-ID: 214692 [Multi-domain] Cd Length: 201 Bit Score: 45.18 E-value: 4.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 25 FIPRAPQRQMIAEVAKTLggdegRHLAIEAPTGVGKTLSYLIPGIAIAREEQ--KTLVVStANVALQDQIFSKdlplLRK 102
Cdd:smart00487 7 EPLRPYQKEAIEALLSGL-----RDVILAAPTGSGKTLAALLPALEALKRGKggRVLVLV-PTRELAEQWAEE----LKK 76
|
90 100
....*....|....*....|....*
gi 490520429 103 IIPELRFTAAFGRGRYVCPRNLAAL 127
Cdd:smart00487 77 LGPSLGLKVVGLYGGDSKREQLRKL 101
|
|
| DEAD |
pfam00270 |
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. ... |
28-116 |
2.91e-04 |
|
DEAD/DEAH box helicase; Members of this family include the DEAD and DEAH box helicases. Helicases are involved in unwinding nucleic acids. The DEAD box helicases are involved in various aspects of RNA metabolism, including nuclear transcription, pre mRNA splicing, ribosome biogenesis, nucleocytoplasmic transport, translation, RNA decay and organellar gene expression.
Pssm-ID: 425570 [Multi-domain] Cd Length: 165 Bit Score: 42.23 E-value: 2.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 28 RAPQRQMIAEVAktlggdEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQ---KTLVVS-TanVALQDQIFSKdlplLRKI 103
Cdd:pfam00270 1 TPIQAEAIPAIL------EGRDVLVQAPTGSGKTLAFLLPALEALDKLDngpQALVLApT--RELAEQIYEE----LKKL 68
|
90
....*....|...
gi 490520429 104 IPELRFTAAFGRG 116
Cdd:pfam00270 69 GKGLGLKVASLLG 81
|
|
| SF2_C_XPD |
cd18788 |
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; ... |
595-673 |
5.50e-04 |
|
C-terminal helicase domain of xeroderma pigmentosum group D (XPD) family DEAD-like helicases; The xeroderma pigmentosum group D (XPD)-like family members are DEAD-box helicases belonging to superfamily (SF)2. This family includes DDX11 (also called ChlR1), a protein involved in maintaining chromosome transmission fidelity and genome stability, the TFIIH basal transcription factor complex XPD subunit, and FANCJ (also known as BRIP1), a DNA helicase required for the maintenance of chromosomal stability. Similar to SF1 helicases, SF2 helicases do not form toroidal structures like SF3-6 helicases. Their helicase core consists of two similar protein domains that resemble the fold of the recombination protein RecA. This model describes the C-terminal domain, also called HelicC.
Pssm-ID: 350175 [Multi-domain] Cd Length: 159 Bit Score: 41.05 E-value: 5.50e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 595 AEGLDLKGELLSQVHIHKIAFPPVDSPVVVtegewLKSLNRYPFEVQSLPAASFSLIQQ--------VGRLIRSHSCWGE 666
Cdd:cd18788 77 SEGIDFSDDLGRAVIMVGIPYPNTKDPILK-----LKMDDLEYLRDKGLLTGEDWYTFQamravnqaIGRAIRHKNDYGA 151
|
....*..
gi 490520429 667 VVIYDRR 673
Cdd:cd18788 152 IVLLDKR 158
|
|
| DEADc_DDX51 |
cd17956 |
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by ... |
7-67 |
1.61e-03 |
|
DEAD-box helicase domain of DEAD box protein 51; DDX51 aids cell cancer proliferation by regulating multiple signalling pathways. Mammalian DEAD box protein Ddx51 acts in 3' end maturation of 28S rRNA by promoting the release of U8 snoRNA.It is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350714 [Multi-domain] Cd Length: 231 Bit Score: 40.69 E-value: 1.61e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490520429 7 QKSQIAAWYkALQQQIpdfIPrapqrqMIAEVAKTLGGDEGRHLAIEAPTGVGKTLSYLIP 67
Cdd:cd17956 6 QNNGITSAF-PVQAAV---IP------WLLPSSKSTPPYRPGDLCVSAPTGSGKTLAYVLP 56
|
|
| DEXHc_Hrq1-like |
cd17923 |
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a ... |
46-115 |
2.53e-03 |
|
DEAH-box helicase domain of Hrq1 and similar proteins; Yeast Hrq1, similar to RecQ4, plays a role in DNA inter-strand crosslink (ICL) repair and in telomere maintenance. Hrq1 lacks the Sld2-like domain found in RecQ4. Hrq1 belongs to the type II DEAD box helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.
Pssm-ID: 350681 [Multi-domain] Cd Length: 182 Bit Score: 39.49 E-value: 2.53e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490520429 46 EGRHLAIEAPTGVGKTLSYLIPGI-AIAREEQ-KTLVVSTANvAL-QDQIFSkdlplLRKIIPELRFTAAFGR 115
Cdd:cd17923 14 AGRSVVVTTGTASGKSLCYQLPILeALLRDPGsRALYLYPTK-ALaQDQLRS-----LRELLEQLGLGIRVAT 80
|
|
| DEADc |
cd00268 |
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family ... |
46-69 |
4.46e-03 |
|
DEAD-box helicase domain of DEAD box helicases; DEAD-box helicases comprise a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350669 [Multi-domain] Cd Length: 196 Bit Score: 38.96 E-value: 4.46e-03
10 20
....*....|....*....|....
gi 490520429 46 EGRHLAIEAPTGVGKTLSYLIPGI 69
Cdd:cd00268 26 SGRDVIGQAQTGSGKTLAFLLPIL 49
|
|
| Lhr |
COG1201 |
Lhr-like helicase [Replication, recombination and repair]; |
27-63 |
4.73e-03 |
|
Lhr-like helicase [Replication, recombination and repair];
Pssm-ID: 440814 [Multi-domain] Cd Length: 850 Bit Score: 40.47 E-value: 4.73e-03
10 20 30
....*....|....*....|....*....|....*..
gi 490520429 27 PRAPQRQMIAEVAktlggdEGRHLAIEAPTGVGKTLS 63
Cdd:COG1201 25 PTPPQREAWPAIA------AGESTLLIAPTGSGKTLA 55
|
|
| DEADc_DDX55 |
cd17960 |
DEAD-box helicase domain of DEAD box protein 55; DDX55 is a member of the DEAD-box helicases, ... |
51-108 |
8.14e-03 |
|
DEAD-box helicase domain of DEAD box protein 55; DDX55 is a member of the DEAD-box helicases, a diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker B motif (motif II). This domain contains the ATP-binding region.
Pssm-ID: 350718 [Multi-domain] Cd Length: 202 Bit Score: 38.33 E-value: 8.14e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490520429 51 AIEAPTGVGKTLSYLIPGIAI--AREEQKT------LVVSTANvALQDQIFSKDLPLLRKIIPELR 108
Cdd:cd17960 31 VVEAVTGSGKTLAFLIPVLEIllKRKANLKkgqvgaLIISPTR-ELATQIYEVLQSFLEHHLPKLK 95
|
|
| SSL2 |
COG1061 |
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair]; |
4-81 |
9.63e-03 |
|
Superfamily II DNA or RNA helicase [Transcription, Replication, recombination, and repair];
Pssm-ID: 440681 [Multi-domain] Cd Length: 566 Bit Score: 39.24 E-value: 9.63e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490520429 4 TAAQKSQIAAWYKALQQQIPDFIPRAPQRQMIAEVAKTLGGDEGRHLaIEAPTGVGKTLSylipGIAIARE---EQKTLV 80
Cdd:COG1061 58 TERELAEAEALEAGDEASGTSFELRPYQQEALEALLAALERGGGRGL-VVAPTGTGKTVL----ALALAAEllrGKRVLV 132
|
.
gi 490520429 81 V 81
Cdd:COG1061 133 L 133
|
|
| |
