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Conserved domains on  [gi|490521774|ref|WP_004387215|]
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MULTISPECIES: fluoride efflux transporter CrcB [Cronobacter]

Protein Classification

fluoride efflux transporter CrcB( domain architecture ID 10014599)

fluoride efflux transporter CrcB is important for reducing fluoride concentration in the cell, thus reducing its toxicity

Gene Ontology:  GO:0005253|GO:1903425|GO:1903424
PubMed:  27449280|28952925|29393634
TCDB:  1.A.43.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
1-127 2.38e-56

fluoride efflux transporter CrcB;


:

Pssm-ID: 184564  Cd Length: 127  Bit Score: 171.17  E-value: 2.38e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:PRK14196   1 MLQSLLAVFIGAGLGALLRWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLSVR 127
Cdd:PRK14196  81 STFSAEVVTLLQEGRFGWALLNVALHLLGSLAMTALGFWTFSALAAH 127
 
Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
1-127 2.38e-56

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 171.17  E-value: 2.38e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:PRK14196   1 MLQSLLAVFIGAGLGALLRWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLSVR 127
Cdd:PRK14196  81 STFSAEVVTLLQEGRFGWALLNVALHLLGSLAMTALGFWTFSALAAH 127
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 2-125 3.86e-33

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 112.50  E-value: 3.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWLGLRLNPVH-HAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFgSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSPELRLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLS 125
Cdd:COG0239   81 STFSLETVRLLERGRYLLALLYVLLSVVLGLLAAALGLALARRLA 125
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 6-121 7.46e-29

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 101.31  E-value: 7.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774    6 LAVFLGGGTGSVLRWWLGLRLNPVHHA--IPVGTLTANLAGAFIIGAgLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGLFGnsLPLGTLTVNIIGCFGIGF-VTLFTQPAVISPDLKLLIGTGFLGGFTTFSTF 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 490521774   84 SAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLF 121
Cdd:TIGR00494  80 SLETTSLLQEGQLGEAVLYILGTLGGGLIGVALGWLLA 117
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 7-116 1.44e-27

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 97.54  E-value: 1.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774    7 AVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHlDPMWKLLITTGLCGGLTTFSTFSAE 86
Cdd:pfam02537   1 LVALGGALGALLRYLLSLLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGH-SPELRLLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|
gi 490521774   87 VVFLLQEGRIGWAGLNMALNLFGSFMMTAL 116
Cdd:pfam02537  80 TLTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
 
Name Accession Description Interval E-value
PRK14196 PRK14196
fluoride efflux transporter CrcB;
1-127 2.38e-56

fluoride efflux transporter CrcB;


Pssm-ID: 184564  Cd Length: 127  Bit Score: 171.17  E-value: 2.38e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:PRK14196   1 MLQSLLAVFIGAGLGALLRWLLGLRLNPLFPALPLGTLAANLIGGYIIGVAVAWFARMPGLDPEWRLLIITGFCGGLTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLSVR 127
Cdd:PRK14196  81 STFSAEVVTLLQEGRFGWALLNVALHLLGSLAMTALGFWTFSALAAH 127
CrcB COG0239
Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell ...
 2-125 3.86e-33

Fluoride ion exporter CrcB/FEX, affects chromosome condensation [Cell cycle control, cell division, chromosome partitioning, Inorganic ion transport and metabolism];


Pssm-ID: 440009  Cd Length: 125  Bit Score: 112.50  E-value: 3.86e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWLGLRLNPVH-HAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:COG0239    1 MKTLLLVALGGALGALLRYLLSLLLPRLFgSGFPWGTLAVNVLGSFLLGLLLGLLARRGLLSPELRLLLGTGFLGGFTTF 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLS 125
Cdd:COG0239   81 STFSLETVRLLERGRYLLALLYVLLSVVLGLLAAALGLALARRLA 125
crcB TIGR00494
protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with ...
 6-121 7.46e-29

protein CrcB; The role of this protein is uncharacterized, but phenotypes associated with overproduction include resistance to camphor, suppression of a mukB chromosomal partition mutant, and chromosome condensation, together suggesting a function related to chromosome folding. [Unknown function, General]


Pssm-ID: 129585  Cd Length: 117  Bit Score: 101.31  E-value: 7.46e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774    6 LAVFLGGGTGSVLRWWLGLRLNPVHHA--IPVGTLTANLAGAFIIGAgLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:TIGR00494   1 LAIFLGGGPGALLRYLLGIFISAGLFGnsLPLGTLTVNIIGCFGIGF-VTLFTQPAVISPDLKLLIGTGFLGGFTTFSTF 79

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 490521774   84 SAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLF 121
Cdd:TIGR00494  80 SLETTSLLQEGQLGEAVLYILGTLGGGLIGVALGWLLA 117
CRCB pfam02537
CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane ...
 7-116 1.44e-27

CrcB-like protein, Camphor Resistance (CrcB); CRCB is a family of bacterial integral membrane proteins with four TMs.. Over expression in E. coli also leads to camphor resistance.


Pssm-ID: 460582  Cd Length: 109  Bit Score: 97.54  E-value: 1.44e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774    7 AVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHlDPMWKLLITTGLCGGLTTFSTFSAE 86
Cdd:pfam02537   1 LVALGGALGALLRYLLSLLNPRLAGGFPLGTLAVNVLGSFLLGLLAGLLLERGH-SPELRLLLGTGFCGGLTTFSTFSLE 79

                          90       100       110
                  ....*....|....*....|....*....|
gi 490521774   87 VVFLLQEGRIGWAGLNMALNLFGSFMMTAL 116
Cdd:pfam02537  80 TLTLLRAGQYLLALLYVLLSVVLGLAAVVL 109
PRK14223 PRK14223
fluoride efflux transporter CrcB;
5-113 2.55e-18

fluoride efflux transporter CrcB;


Pssm-ID: 184576  Cd Length: 122  Bit Score: 74.72  E-value: 2.55e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGlRLNPVHHAIPVGTLTANLAGAFIIGAgLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFS 84
Cdd:PRK14223   4 LLLIGIGGFFGAILRYLIS-GIIPVKFGIPTGTLIVNLIGSFILGF-LLYSSLFGSISPEYRLFIITGFCGALTTFSTFS 81

                         90       100
                 ....*....|....*....|....*....
gi 490521774  85 AEVVFLLQEGRIGWAGLNMALNLFGSFMM 113
Cdd:PRK14223  82 YETFSLLEEGLYIKALLNILLNVFGCLIM 110
PRK14207 PRK14207
fluoride efflux transporter CrcB;
2-120 1.81e-17

fluoride efflux transporter CrcB;


Pssm-ID: 172695  Cd Length: 123  Bit Score: 72.47  E-value: 1.81e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWLGLRLnPVHHAIPVGTLTANLAGAFIIGA--GLAWFNrmTHLDPMWKLLITTGLCGGLTT 79
Cdd:PRK14207   3 AKIALAVAIGGGLGALARYYISGLL-PVYKDFPVGTLLVNSIASFILGYlyGLLFWG--FDVSPEWRAFLGTGFCGGLST 79

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 490521774  80 FSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWL 120
Cdd:PRK14207  80 FSTFSYETFSLLREREYLLALLNISANVLITISLVFLGFIL 120
PRK14197 PRK14197
fluoride efflux transporter CrcB;
5-123 2.67e-15

fluoride efflux transporter CrcB;


Pssm-ID: 172685  Cd Length: 124  Bit Score: 66.70  E-value: 2.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLG-LRLNPVHHAIPVGTLTANLAGAFIIGAGLAwFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14197   4 VLFVALGGSIGAVLRYLISiFMIQVFGSSFPFGTLLVNVLGSFLMGVIYA-LGQMSHVSPELKALIGVGLLGALTTFSTF 82

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 490521774  84 SAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSS 123
Cdd:PRK14197  83 SNETLLLMQEGAWLKAALNVVLNLSLCLFMVYLGQQLVFS 122
PRK14227 PRK14227
fluoride efflux transporter CrcB;
6-124 6.07e-14

fluoride efflux transporter CrcB;


Pssm-ID: 172715  Cd Length: 124  Bit Score: 63.32  E-value: 6.07e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWLGLRLNPVHHA-IPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFS 84
Cdd:PRK14227   5 IVVAIGGSIGAILRYFTGVYSAKNLGLdFPYGTLIVNSVGSFILSFFMILFLEKLSLDPLWRLFVAVGFCGSFTTFSSFT 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 490521774  85 AEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSL 124
Cdd:PRK14227  85 YETIALFQDGDYTKAMLNIILNNVLSITSAFSGIVLARVL 124
PRK14206 PRK14206
fluoride efflux transporter CrcB;
6-120 6.23e-14

fluoride efflux transporter CrcB;


Pssm-ID: 172694  Cd Length: 127  Bit Score: 63.29  E-value: 6.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWL-GLRLNPVHHAIPVGTLTANLAGAFIIG--AGLAWFNRMTHLDPMWKLLITTGLCGGLTTFST 82
Cdd:PRK14206   4 LWIALGSALGGTLRFWLsGLVAEATGGTFPWGTLVINVSGSFLIGffATLTGPEGRVFVGESWRLFVMVGVCGGFTTFSS 83

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 490521774  83 FSAEVVFLLQEGRIGWAGLNMAlnlfGSFMMTALAFWL 120
Cdd:PRK14206  84 FSLQTLNLARDGDWLRAGGNVV----LSVVFCLLAVWL 117
PRK14202 PRK14202
fluoride efflux transporter CrcB;
1-112 1.33e-13

fluoride efflux transporter CrcB;


Pssm-ID: 172690  Cd Length: 128  Bit Score: 62.42  E-value: 1.33e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFL---GGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGL 77
Cdd:PRK14202   1 MMEQFSAVLLvgaGGFLGSVARYLVALALSFIGTGFPFATFTVNLLGSFLIGFISELALSTTLVSPEARLLLVTGFCGGF 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490521774  78 TTFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFM 112
Cdd:PRK14202  81 TTFSSYMYEIAALLRDGELFYASLYLAGSLVGGFV 115
PRK14195 PRK14195
fluoride efflux transporter CrcB;
5-104 1.90e-13

fluoride efflux transporter CrcB;


Pssm-ID: 184563  Cd Length: 125  Bit Score: 61.97  E-value: 1.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGL-RLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14195   4 ILLVAAGGALGSVARYLVGVgALRLMGPAFPWGTLAVNVTGSFLIGVLAGLLAHRWNASQEWRLFLIVGVLGGFTTFSAF 83

                         90       100
                 ....*....|....*....|.
gi 490521774  84 SAEVVFLLQEGRIGWAGLNMA 104
Cdd:PRK14195  84 SLDAALLIERGAYGAAAAYIA 104
PRK14199 PRK14199
fluoride efflux transporter CrcB;
1-117 5.47e-13

fluoride efflux transporter CrcB;


Pssm-ID: 172687  Cd Length: 128  Bit Score: 60.95  E-value: 5.47e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVF--LGGGTGSVLRWWLGLRLNPVHHA-IPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGL 77
Cdd:PRK14199   1 MEKLILAIIvgLGGFIGASLRYLISIFAAKMFNGnFPYGTLIVNIVGALLIGFIMEFSMDTALISSNMKLFLTTGIMGGL 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 490521774  78 TTFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALA 117
Cdd:PRK14199  81 TTFSTFSYETINLITNGNILLGIENIILNLGLSLLGVVIG 120
PRK14212 PRK14212
fluoride efflux transporter CrcB;
5-125 2.26e-12

fluoride efflux transporter CrcB;


Pssm-ID: 184569  Cd Length: 128  Bit Score: 59.44  E-value: 2.26e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGL-RLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14212   4 ILLLAAGGALGAVSRYGLNNlTVKLLGDSFPYGTLIVNCLGCFVLGFLMQWGFSSDSHNTHLKLMLTAGFLGAFTTFSTF 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 490521774  84 SAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLS 125
Cdd:PRK14212  84 SYETLDCFKAGDYFNGFSNILANVLLGLLMVFIGAYLGSLLK 125
PRK14210 PRK14210
fluoride efflux transporter CrcB;
2-94 6.92e-11

fluoride efflux transporter CrcB;


Pssm-ID: 172698  Cd Length: 127  Bit Score: 55.40  E-value: 6.92e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWLGLRL----NPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMtHLDPMWKLLITTGLCGGL 77
Cdd:PRK14210   1 MKEIIYIFIGGGMGSVTRYLTQIAVnerlSPALFPFPWGTFAVNIIGSLLIGFFYSFSERF-NLSFELRLFLTVGFCGGF 79

                         90
                 ....*....|....*..
gi 490521774  78 TTFSTFSAEVVFLLQEG 94
Cdd:PRK14210  80 TTFSTLANDSLSLLKGG 96
PRK14222 PRK14222
fluoride efflux transporter CrcB;
2-116 1.40e-10

fluoride efflux transporter CrcB;


Pssm-ID: 172710  Cd Length: 124  Bit Score: 54.72  E-value: 1.40e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWL-GLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:PRK14222   1 METLVYIALFGALGCLARYYLsGWVYALFGRAFPYGTLAVNVIGAFLIGLIMEFSLRSTLIPPTLRIGLTIGFLGGLTTF 80

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTAL 116
Cdd:PRK14222  81 STFSYETFRLLEDGELLIASVNVLASVVVCLVCTWL 116
PRK14216 PRK14216
fluoride efflux transporter CrcB;
2-127 2.07e-10

fluoride efflux transporter CrcB;


Pssm-ID: 184572  Cd Length: 132  Bit Score: 54.46  E-value: 2.07e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFS 81
Cdd:PRK14216   6 YRELAAVFAGGALGTLARAALSELAAPDPARWPWPTFTVNVVGAFLLGYFTTRLLERLPLSSYRRPLLGTGLCGGLTTFS 85

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 490521774  82 TFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSLSVR 127
Cdd:PRK14216  86 TMQVETIRMIEHGHWGLAAGYTAASIAAGLLAVHLATVLVRRVRIR 131
PRK14201 PRK14201
fluoride efflux transporter CrcB;
6-96 2.11e-10

fluoride efflux transporter CrcB;


Pssm-ID: 184566  Cd Length: 121  Bit Score: 53.94  E-value: 2.11e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWLGLrLNpVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFSA 85
Cdd:PRK14201   4 VYIFIGGALGALLRYLLSF-LN-TDGGFPIGTLIANLTGAFLMGLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQF 81

                         90
                 ....*....|.
gi 490521774  86 EVVFLLQEGRI 96
Cdd:PRK14201  82 ELIHMFDHQQF 92
PRK14230 PRK14230
camphor resistance protein CrcB; Provisional
 1-118 7.59e-10

camphor resistance protein CrcB; Provisional


Pssm-ID: 172718  Cd Length: 119  Bit Score: 52.77  E-value: 7.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLnPVHHAIPVGTLTANLAGAFIIGAGLAWFNRmthldPMWKLLITTGLCGGLTTF 80
Cdd:PRK14230   1 MLSNIIPLSIGAALGATARWLLNLAV-PASLSPATGNLFANWTGALLIGIFAETVNH-----PQWKLLLITGFLGSLTTL 74

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 490521774  81 STFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAF 118
Cdd:PRK14230  75 SGFSLETVTLLQSNRPASALANIFLHTAGSLLLTWLGL 112
PRK14200 PRK14200
fluoride efflux transporter CrcB;
34-120 2.56e-09

fluoride efflux transporter CrcB;


Pssm-ID: 237638  Cd Length: 127  Bit Score: 51.34  E-value: 2.56e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774  34 PVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMM 113
Cdd:PRK14200  37 PYGTLTVNVVGSFIMGLLIAAFENELLATEPWRQIIGLGFLGALTTFSTFSMDNVLLMQQGAFFKMGLNVLLNVVLSISA 116


                 ....*..
gi 490521774 114 TALAFWL 120
Cdd:PRK14200 117 AWIGFQL 123
PRK14219 PRK14219
fluoride efflux transporter CrcB;
4-120 3.85e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172707  Cd Length: 132  Bit Score: 51.00  E-value: 3.85e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   4 IMLAVFLGGGTGSVLRWWLGLRLNPV-HHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFST 82
Cdd:PRK14219   2 IYIIVGIAGILGALSRYYLGLTIHEFwHHTFPLATLLINLAGCFLLAWLTTYIAKLNILPSDVITGIGTGFIGSFTTFST 81

                         90       100       110
                 ....*....|....*....|....*....|....*...
gi 490521774  83 FSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWL 120
Cdd:PRK14219  82 FSVETIQLINHSEWSIAFLYVSCSILGGLIMSGLGYTL 119
PRK14213 PRK14213
camphor resistance protein CrcB; Provisional
 7-119 4.98e-09

camphor resistance protein CrcB; Provisional


Pssm-ID: 184570  Cd Length: 118  Bit Score: 50.59  E-value: 4.98e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   7 AVFLGGGTGSVLRWWLGLRLNPVHH--AIPVGTLTANLAGAFiigaGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFS 84
Cdd:PRK14213   5 GIFIAGGIGAVLRFWLGNVITAKTKglSLPIGIMTVNILGSF----GLGIFTGLGVDNASVSIIIGTGFFGAFTTFSTFS 80

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490521774  85 AEVVFLLQEGRIGWAGLNMALNLFGSFmmtaLAFW 119
Cdd:PRK14213  81 VEAVQLLMAKRVKESILYIALTLAGSL----LAFW 111
PRK14198 PRK14198
fluoride efflux transporter CrcB;
6-101 6.90e-09

fluoride efflux transporter CrcB;


Pssm-ID: 172686  Cd Length: 124  Bit Score: 50.13  E-value: 6.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWLG-LRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFS 84
Cdd:PRK14198   4 LLVFVGGGLGASLRHAVNmASARLLGTSFPYGTFIINVSGSLVMGLIAGYLAFKGGAPQHWRLFLMTGILGGYTTFSAFS 83

                         90
                 ....*....|....*..
gi 490521774  85 AEVVFLLQEGRIGWAGL 101
Cdd:PRK14198  84 LDAALLYERGALGLAAL 100
PRK14234 PRK14234
fluoride efflux transporter CrcB;
1-114 1.93e-08

fluoride efflux transporter CrcB;


Pssm-ID: 172722  Cd Length: 124  Bit Score: 49.00  E-value: 1.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLN---PVHHAipVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGL 77
Cdd:PRK14234   1 MIRLILAVSAGGIAGTLLRFATGNWVSanwPRHFY--AATLAVNIVGCLLIGLLYGLFLLRPEVPIELRAGLIVGFLGGL 78

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 490521774  78 TTFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMT 114
Cdd:PRK14234  79 TTFSSFSLDTLRLLESGQVPLALGYAGISVFGGLLAT 115
PRK14211 PRK14211
fluoride efflux transporter CrcB;
5-92 2.91e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172699  Cd Length: 114  Bit Score: 45.69  E-value: 2.91e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGlRLNPVHHAIPVGTLTANLAGAFIIG--AGLAWFNRMThldpmwkLLITTGLCGGLTTFST 82
Cdd:PRK14211   3 VLLVALGGALGATTRYLTG-RYVDSYRSFPVATFLVNVAGCLILGllSGASLSTQTF-------ALLGTGFCGGLTTYST 74

                         90
                 ....*....|
gi 490521774  83 FSAEVVFLLQ 92
Cdd:PRK14211  75 FAVESVGLLR 84
PRK14229 PRK14229
fluoride efflux transporter CrcB;
4-93 2.99e-07

fluoride efflux transporter CrcB;


Pssm-ID: 172717  Cd Length: 108  Bit Score: 45.60  E-value: 2.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   4 IMLAVFLGGGTGSVLRWWLGlRLNPvHHAIPVGTLTANLAGAFIIGAglaWFNRMThlDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14229   1 VIVYLAIACGLGALVRYFFS-RYNQ-ASKLPLGTLIANLLGCFLIGV---FYNHVE--SKEVYAILATGFCGGLTTFSTL 73

                         90
                 ....*....|
gi 490521774  84 SAEVVFLLQE 93
Cdd:PRK14229  74 NDELQRLLSD 83
PRK14209 PRK14209
fluoride efflux transporter CrcB;
1-117 4.99e-07

fluoride efflux transporter CrcB;


Pssm-ID: 237640  Cd Length: 124  Bit Score: 45.31  E-value: 4.99e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRL-NPVHHAIPVGTLTANLAGAFIIGAGLAwfnRMTHLDPMWKLLITTGLCGGLTT 79
Cdd:PRK14209   1 MISSLLQVALGGALGASARYLTNVGSmRLFGPAFPVGTMIVNVVGSFLMGVLVV---VLAHKGNRYAPFLMTGMLGGFTT 77

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 490521774  80 FSTFSAEVVFLLQEGRIGWA----GLNMALNLFGSFMMTALA 117
Cdd:PRK14209  78 FSAFSLDAVTLYERGQAGLAaayvGLSVGLSLAGLMAGMAAV 119
PRK14218 PRK14218
fluoride efflux transporter CrcB;
5-113 1.06e-06

fluoride efflux transporter CrcB;


Pssm-ID: 184573  Cd Length: 133  Bit Score: 44.49  E-value: 1.06e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGLRL-NPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14218  10 LLLVMLGGAFGSGLRFVIGSCLlQRFGAGFPWGTLAVNLIGSFVAGFLLIWLDKRGSAGWPWRMLLIVGLIGGLTTFSSL 89

                         90       100       110
                 ....*....|....*....|....*....|
gi 490521774  84 SAEVVFLLQEGRIGWAGLNMALNLFGSFMM 113
Cdd:PRK14218  90 MMECLVFVRSDRSLMVGIYLCITLLFGLLF 119
PRK14226 PRK14226
fluoride efflux transporter CrcB;
4-120 1.38e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172714  Cd Length: 130  Bit Score: 44.10  E-value: 1.38e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   4 IMLAVFLGGGTGSVLRWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMT----HLDPMWKLLITTGLCGGLTT 79
Cdd:PRK14226   4 LLLLVGIGGGFGAMARFALTQATASISKQIPLGILLCNIIGSLIIGMMAAFLIETKlfneDVSTYVRFLLVTGFLGGFTT 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 490521774  80 FSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWL 120
Cdd:PRK14226  84 FSSFSLDILNLLQRGEIFIAIGYIMVSVLASLIAVILGFYI 124
PRK14215 PRK14215
fluoride efflux transporter CrcB;
5-120 1.74e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172703  Cd Length: 126  Bit Score: 44.04  E-value: 1.74e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWLGL-RLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTF 83
Cdd:PRK14215   4 ILAIAVGAAIGANLRYGIGLwAAQRWGTSWPYGTFIINLLGCLLIGLLLTLATTRLTLSEPARLMLVTGLLGGFTTFSTF 83

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 490521774  84 SAEVVFLLQEGRIGWAGLNMA----LNLFGSFMMTALAFWL 120
Cdd:PRK14215  84 GYESYSLLSSGNWLAAGGYVVgsvgGGLIAVIIGAGLGRWL 124
PRK14233 PRK14233
fluoride efflux transporter CrcB;
1-126 4.46e-06

fluoride efflux transporter CrcB;


Pssm-ID: 172721  Cd Length: 133  Bit Score: 42.95  E-value: 4.46e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWL----GLRLNpvhHAIPVGTLTANLAGAFIIG--AGLAWFNRMTHLDPMWKLLITTGLC 74
Cdd:PRK14233   2 SVEASILVLVGGFIGGVMRFFLsgyvGRRIG---ETFPWGTFVVNVSGAFVIGtaAGLGARLGGIFSTTIFHEFIMVGLL 78

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 490521774  75 GGLTTFSTFSAEVVFLLQEGRIGWAGLNMALNlfGSFMMTALAFWLFSSLSV 126
Cdd:PRK14233  79 GGYTTVSSFCLQSVNLMLDGEQRQALFNIVAS--ALLCVLAVAAGYGGIMWI 128
PRK14203 PRK14203
fluoride efflux transporter CrcB;
2-124 1.01e-05

fluoride efflux transporter CrcB;


Pssm-ID: 237639  Cd Length: 132  Bit Score: 42.11  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   2 LKIMLAVFLGGGTGSVLRWWL-GLRLNPVHHAIPVGTLTANLAGAFIIG--AGLAWFNRMTHLDPMWKLLITTGLCGGLT 78
Cdd:PRK14203   5 LTGLIWVALGSVLGGPARFFLsGLVARRIGETFPWGTLTVNVSGAFAIGifGALAASGHGLFALPAPWLFAVTGFLGCYT 84

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 490521774  79 TFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWLFSSL 124
Cdd:PRK14203  85 TVSSFSLQTLTLARDGEFLRALGNVAFSLILCLIAVAIGFAAATGL 130
PRK14224 PRK14224
fluoride efflux transporter CrcB;
34-112 1.39e-05

fluoride efflux transporter CrcB;


Pssm-ID: 237642  Cd Length: 126  Bit Score: 41.30  E-value: 1.39e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490521774  34 PVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFSAEVVFLLQEGRIGWAGLNMALNLFGSFM 112
Cdd:PRK14224  35 QLGTLSVNVLGSFMLGMIMYDTEYIGFIGPKGRLAFGTGFLGAFTTFSTFAVQSFSMPFVPALGNISANLFLTLTGVFF 113
PRK14217 PRK14217
fluoride efflux transporter CrcB;
6-113 6.68e-05

fluoride efflux transporter CrcB;


Pssm-ID: 172705  Cd Length: 134  Bit Score: 39.99  E-value: 6.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWLGLRL-NPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFS 84
Cdd:PRK14217   7 LAVAIGGSLGAMSRYLVTIMAqNAWGIKFPYGTLLVNTLGSFLAGFFLIVLVGRFSAEESFRLFLFTGFLGAFTTFSSFA 86

                         90       100
                 ....*....|....*....|....*....
gi 490521774  85 AEVVFLLQEGRIGWAGLNMALNLFGSFMM 113
Cdd:PRK14217  87 AESLFMFEQGYWFKLITNILVNNVGSLSM 115
PRK14208 PRK14208
fluoride efflux transporter CrcB;
5-120 8.42e-05

fluoride efflux transporter CrcB;


Pssm-ID: 172696  Cd Length: 126  Bit Score: 39.56  E-value: 8.42e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRW----WLGLRLNPvhhAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTF 80
Cdd:PRK14208   4 LLLVCLGGALGSGARYltsaWALRAFGP---DFPRGTLLVNVSGSFLLAGIMTASLQSEAVPPDLRLFLAAGVMGGFTTY 80

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*
gi 490521774  81 STFSAEVVFLLQEGRIGwAGLNMALN-----LFGSFMMTALAFWL 120
Cdd:PRK14208  81 SSFNYETLALLEQGRLA-AAAAYLLAtvlgcLAAAFAATLLVRWL 124
PRK14214 PRK14214
fluoride efflux transporter CrcB;
1-86 4.37e-04

fluoride efflux transporter CrcB;


Pssm-ID: 184571  Cd Length: 118  Bit Score: 37.15  E-value: 4.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   1 MLKIMLAVFLGGGTGSVLRWWLGLRLNPVHHA-IPVGTLTANLAGAFIIGaglawFNRMTHLDPMWKLLITTGLCGGLTT 79
Cdd:PRK14214   1 MLVNFLLVGFGAALGAMLRYGISVLVKSKWKTnFPYATFFINITGSFLLG-----FLVSSALGPVWQLFLGTGFMGGYTT 75


                 ....*..
gi 490521774  80 FSTFSAE 86
Cdd:PRK14214  76 FSTFKVE 82
ccrB PRK01636
fluoride efflux transporter CrcB;
19-83 5.31e-04

fluoride efflux transporter CrcB;


Pssm-ID: 179312  Cd Length: 118  Bit Score: 37.05  E-value: 5.31e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490521774  19 RWWLGLRLNPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMwKLLITTGLCGGLTTFSTF 83
Cdd:PRK01636   3 REFIMLSVPRLADGFPLDIFVANVVAAFLLGLTTSLHKRDKISQYV-HLMIGTGIMGGLSTFSSF 66
PRK14221 PRK14221
fluoride efflux transporter CrcB;
6-120 1.69e-03

fluoride efflux transporter CrcB;


Pssm-ID: 184575  Cd Length: 124  Bit Score: 35.93  E-value: 1.69e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   6 LAVFLGGGTGSVLRWWLGLRLnPVHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPMWKLLITTGLCGGLTTFSTFSA 85
Cdd:PRK14221   9 LGIFLAAMLGGLVRYLVSTWL-PASPDFPWGTLFVNYLGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLML 87

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490521774  86 EVVFLLQEGRIGWAGLNMALNLFGSFmmtALAFWL 120
Cdd:PRK14221  88 DTVKLLDTGRYLSLILYLLLSIGGGL---LLAYYL 119
PRK14220 PRK14220
fluoride efflux transporter CrcB;
5-120 2.83e-03

fluoride efflux transporter CrcB;


Pssm-ID: 237641  Cd Length: 120  Bit Score: 35.13  E-value: 2.83e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   5 MLAVFLGGGTGSVLRWWL---GLRLNPVHHAIPVGTLTANLAGAFIIGAGLAwfnrmTHLDPMWKLLITTGLCGGLTTFS 81
Cdd:PRK14220   3 ILLAGFGASIGAMLRYAItnyGKKHWEQFSNLPTPTLLINLTGAFILGLIFG-----RKFNPFIYALLGTGVLGGYTTFS 77

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 490521774  82 TFSAEVVFLLQEGRIGWAGLNMALNLFGSFMMTALAFWL 120
Cdd:PRK14220  78 TLNTELVSLYKSKNYRVLKLYALLSYLGGLILVFCGYYL 116
PRK14204 PRK14204
fluoride efflux transporter CrcB;
4-95 8.01e-03

fluoride efflux transporter CrcB;


Pssm-ID: 172692  Cd Length: 127  Bit Score: 34.13  E-value: 8.01e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490521774   4 IMLAVFLGGGTGSVLRWWLGLRLNP---VHHAIPVGTLTANLAGAFIIGAGLAWFNRMTHLDPmWKLLITTGLCGGLTTF 80
Cdd:PRK14204   4 VFLWAALGGAIGSSLRYFVGKMMPSkflMFESFPLGTFSVNIIGCFVIGFMGHLAAKKVFGDD-FGIFFVTGVLGGFTTF 82

                         90
                 ....*....|....*
gi 490521774  81 STFSAEVVFLLQEGR 95
Cdd:PRK14204  83 SSYGLDTLKLLQKSQ 97
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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