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Conserved domains on  [gi|490559395|ref|WP_004424456|]
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L-lactate permease [Ectopseudomonas oleovorans]

Protein Classification

L-lactate permease( domain architecture ID 10004073)

L-lactate permease plays a role in L-lactate utilization by transporting L-lactate across the membrane

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


:

Pssm-ID: 441227  Cd Length: 520  Bit Score: 528.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   1 MSNGILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITLGLLWIIFGAILLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  81 TLKHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 161 VGTPIIVGIN-TGLDTASIGAqlveqgsswgqflqlitsQVAIIHATVGVVMPLIMVMMLTRFfgqeKSWKaglEVLPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIK---EVWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 240 IFGGLAFVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPADKWPSEwlgsvemKLDELTAKPMSA 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 320 LRAWLPYVMVGALLVISRVFPEVGNALKAVVVNFP----DLLGEAGVSANFQPLYLPGGILVAVVLATFFLHGMKARDLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 396 KAVKESSSVLLSAGFVLLFTVPMVRILINSGvngaelasMPILMAGWVAESVGGIYPLLAPSIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 476 FSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLYYVLFTGIIAMIAIYVL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 528.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   1 MSNGILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITLGLLWIIFGAILLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  81 TLKHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 161 VGTPIIVGIN-TGLDTASIGAqlveqgsswgqflqlitsQVAIIHATVGVVMPLIMVMMLTRFfgqeKSWKaglEVLPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIK---EVWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 240 IFGGLAFVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPADKWPSEwlgsvemKLDELTAKPMSA 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 320 LRAWLPYVMVGALLVISRVFPEVGNALKAVVVNFP----DLLGEAGVSANFQPLYLPGGILVAVVLATFFLHGMKARDLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 396 KAVKESSSVLLSAGFVLLFTVPMVRILINSGvngaelasMPILMAGWVAESVGGIYPLLAPSIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 476 FSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLYYVLFTGIIAMIAIYVL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
7-551 3.26e-83

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 268.86  E-value: 3.26e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395    7 ALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLLNTLKHS 85
Cdd:pfam02652   3 ALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLwPIAWIIIAAIFLYKISVKS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   86 GGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGAVGTPI 165
Cdd:pfam02652  83 GAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGIPI 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  166 IVGINTGLDTASIgaqlveqgsswgqflqlITSQVAIIHATVGVVMPLIMVMMLTRFFGQEKSWkaglevlPFAIFGGLA 245
Cdd:pfam02652 163 TAGAGATGLSALE-----------------ISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETF-------PAVLVSGLS 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  246 FVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPAdkwpsewlgsvEMKLDELTAKPMSALRAWLP 325
Cdd:pfam02652 219 FAIPQFLSSNVLGPELPSILGALVSLVITALFLK--FWQPKEIFRFAGK-----------GDSGATSALRAGKIVKAWSP 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  326 YVMVGALLVISR-----------------VFPEVGNALKAVVVNFPDLLGEAG---VSANFQPLYLPGGILVAVVLATFF 385
Cdd:pfam02652 286 FVLLTAFIVLWSipqfkalfqeggalytsTFNFEFPEISQLIFSIPPIVGEATpfpVVFKFKLLYSPGTIIFLAALLSIF 365
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  386 LHGMKARDLGKAVKESSSVLLSAGFVLLFTVPMVRILINSGvngaelasMPILMAGWVAESvGGIYPLLAPSIGALGAFI 465
Cdd:pfam02652 366 ILKVSSSDALSIFKETLKEMALPIITIIFVLAFANLMNYSG--------MSKTLALALAHT-GSAFTFFSPFLGWLGVFL 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  466 AGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLYYVLFTG 545
Cdd:pfam02652 437 TGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMGKMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVG 516

                  ....*.
gi 490559395  546 IIAMIA 551
Cdd:pfam02652 517 VVAFLL 522
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
1-553 4.53e-82

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 266.18  E-value: 4.53e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395    1 MSNGILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLL 79
Cdd:TIGR00795   3 VYDWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLwPIAWIIIAAIFLY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   80 NTLKHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFG 159
Cdd:TIGR00795  83 KLSVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  160 AVGTPIIVGINTGLDTASIgaqlveqgsswgqflqlITSQVAIIHATVGVVMPLIMVMMLTRFFGQEKSWkaglevlPFA 239
Cdd:TIGR00795 163 AVGIPIWAGAQATGLSALE-----------------ISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETF-------PAV 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  240 IFGGLAFVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPAdkwpsewlgsvEMKLDELTAKPMSA 319
Cdd:TIGR00795 219 LVAGLSFAIPQFLSSNYLGPELPSILGALVSLVITALFLK--FWQPKEIFRFNGK-----------LDAGEVSAHHICKI 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  320 LRAWLPYVMVGALLVISRVFP-----EVGNALKAVVVNF-------------PDLLGEAGVSANFQPLYLPGGI--LVAV 379
Cdd:TIGR00795 286 VKAWSPFVLLTAFIVLWSIPPfkalfMKGGALIFSSFTFgspglsqhifklpPIVNQATNFPAVFKLLLIIATGtsILLA 365
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  380 VLATFFLHGMKARDLGKAVKESSSvllsagfvLLFTVPMVRILINSGVNGAELASMPILMAGWVAESvGGIYPLLAPSIG 459
Cdd:TIGR00795 366 AIVSFFILRVSISDAIGVFGETLK--------EMRLPILTIGMVLAFANVSNYSGMSKTLALALAHT-GLAFTFFSPFLG 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  460 ALGAFIAGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLY 539
Cdd:TIGR00795 437 WLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLI 516
                         570
                  ....*....|....
gi 490559395  540 YVLFTGIIAMIAIY 553
Cdd:TIGR00795 517 YAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
7-555 1.37e-43

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 163.09  E-value: 1.37e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   7 ALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLLNTLKHS 85
Cdd:PRK10420  18 SLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLwPIAWIIIAAVFVYKISVKT 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  86 GGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGAVGTPI 165
Cdd:PRK10420  98 GQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPI 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 166 IV-GINTGLDTASIGAQlveqgsswgqflqlitsqvaiihatVGVVMPLIMVMMLTRFFGQEKSWKAGLEVLPFAIFGGL 244
Cdd:PRK10420 178 LVaGQVTGIDSFEIGQM-------------------------VGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGG 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 245 AFVLPYAATGIFLGPEFPSLLGGLIGLAIVTsaARFGFLVPKKTWDFAPADKwpsewlGSVEMKLDELTAKPMSALRAWL 324
Cdd:PRK10420 233 SFAIAQYLSSNFIGPELPDIISSLVSLVCLT--LFLKRWQPVRIFRFGDLGA------SQVDMTLAHTGYTAGQVLRAWS 304
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 325 PYVMVGALLVISRVFP-----EVGNALKAVVVNF------------PDLLGEAGVSA---NFQPLYLPG-GILVAVVLAT 383
Cdd:PRK10420 305 PFLFLTATVTLWSIPPfkalfASGGALYEWVINIpvpyldklvarmPPVVSEATAYAavyKFDWFSATGtAILFAALLSI 384
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 384 FFLHgMKARD----LGKAVKESSSVLLSAGFVLLFTVpmvrILINSGVNgaelASMPILMAgwvaeSVGGIYPLLAPSIG 459
Cdd:PRK10420 385 VWLK-MKPSDaistFGSTLKELALPIYSIGMVLAFAF----ISNYSGLS----STLALALA-----HTGHAFTFFSPFLG 450
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 460 ALGAFIAGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLY 539
Cdd:PRK10420 451 WLGVFLTGSDTSSNALFAALQATAAQQIGVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLI 530
                        570
                 ....*....|....*.
gi 490559395 540 YVLFTGIIAMIAIYVL 555
Cdd:PRK10420 531 FTCMVGVITTLQAYVL 546
 
Name Accession Description Interval E-value
LldP COG1620
L-lactate permease [Energy production and conversion];
1-555 0e+00

L-lactate permease [Energy production and conversion];


Pssm-ID: 441227  Cd Length: 520  Bit Score: 528.93  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   1 MSNGILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITLGLLWIIFGAILLLN 80
Cdd:COG1620    1 MSLGLSALLALLPILVLFVLLVVLRWPAHKAMPIGLLVALLVALFVFGMPAGLALAATLQGALFGLPILWIVFGAILLYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  81 TLKHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGA 160
Cdd:COG1620   81 TTVESGAFDVIRRSFASISPDRRVQALLIAFLFGAFLEGAAGFGTPVAITAPLLVGLGFPPLAAAGLALIANTAPVAFGA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 161 VGTPIIVGIN-TGLDTASIGAqlveqgsswgqflqlitsQVAIIHATVGVVMPLIMVMMLTRFfgqeKSWKaglEVLPFA 239
Cdd:COG1620  161 VGTPIIVGAQvTGLDALEIGA------------------MVGRQLPILSLLIPFLLVWILDGW----RGIK---EVWPAA 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 240 IFGGLAFVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPADKWPSEwlgsvemKLDELTAKPMSA 319
Cdd:COG1620  216 LVAGLSFAVPQFLTANFLGPELPDIIAGLVGLAALVLFLR--FWKPKEIWDFAPEEEWPAE-------EEDAEKLSAMSL 286
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 320 LRAWLPYVMVGALLVISRVFPEVGNALKAVVVNFP----DLLGEAGVSANFQPLYLPGGILVAVVLATFFLHGMKARDLG 395
Cdd:COG1620  287 LKAWSPYLLLIVLLVLTRLPPPVKALLNSTTLKIPwpglLGAGTTGASYSFNPLYAPGTAILLAALITILLLRMSPGQAK 366
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 396 KAVKESSSVLLSAGFVLLFTVPMVRILINSGvngaelasMPILMAGWVAESVGGIYPLLAPSIGALGAFIAGSNTVSNMM 475
Cdd:COG1620  367 RAFKETLKQLRGPILTLAFVLALAYVMNYSG--------MPATLGLALAAATGAAFPFFAPFLGWLGVFITGSDTSSNAL 438
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 476 FSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLYYVLFTGIIAMIAIYVL 555
Cdd:COG1620  439 FGGLQFTTAEQLGLSPTLIVAAQSVGGVMGKMISPQNIVAAAAAVGLVGKEGEIIRKTLIPSLILLLLVGLLVLLQAYVL 518
Lactate_perm pfam02652
L-lactate permease; L-lactate permease is an integral membrane protein probably involved in ...
7-551 3.26e-83

L-lactate permease; L-lactate permease is an integral membrane protein probably involved in L-lactate transport.


Pssm-ID: 280762  Cd Length: 522  Bit Score: 268.86  E-value: 3.26e-83
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395    7 ALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLLNTLKHS 85
Cdd:pfam02652   3 ALVALTPILLFFFLLAVLKMKGYYAAPISLAVTVIIALLYYKMPVENTISSVLYGALYGLwPIAWIIIAAIFLYKISVKS 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   86 GGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGAVGTPI 165
Cdd:pfam02652  83 GAFEIIRSSILNISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFGAVGIPI 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  166 IVGINTGLDTASIgaqlveqgsswgqflqlITSQVAIIHATVGVVMPLIMVMMLTRFFGQEKSWkaglevlPFAIFGGLA 245
Cdd:pfam02652 163 TAGAGATGLSALE-----------------ISSMVGFQLPFISLLIPFFLVFLMDGFKGIKETF-------PAVLVSGLS 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  246 FVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPAdkwpsewlgsvEMKLDELTAKPMSALRAWLP 325
Cdd:pfam02652 219 FAIPQFLSSNVLGPELPSILGALVSLVITALFLK--FWQPKEIFRFAGK-----------GDSGATSALRAGKIVKAWSP 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  326 YVMVGALLVISR-----------------VFPEVGNALKAVVVNFPDLLGEAG---VSANFQPLYLPGGILVAVVLATFF 385
Cdd:pfam02652 286 FVLLTAFIVLWSipqfkalfqeggalytsTFNFEFPEISQLIFSIPPIVGEATpfpVVFKFKLLYSPGTIIFLAALLSIF 365
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  386 LHGMKARDLGKAVKESSSVLLSAGFVLLFTVPMVRILINSGvngaelasMPILMAGWVAESvGGIYPLLAPSIGALGAFI 465
Cdd:pfam02652 366 ILKVSSSDALSIFKETLKEMALPIITIIFVLAFANLMNYSG--------MSKTLALALAHT-GSAFTFFSPFLGWLGVFL 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  466 AGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLYYVLFTG 545
Cdd:pfam02652 437 TGSDTSSNLLFGSLQLVTAEQIGLPPVLLLAANTVGGVMGKMISPQSIAIACAAVGLAGKESDLFRKTIKYSLIYAIIVG 516

                  ....*.
gi 490559395  546 IIAMIA 551
Cdd:pfam02652 517 VVAFLL 522
lctP TIGR00795
L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized ...
1-553 4.53e-82

L-lactate transport; The Lactate Permease (LctP) Family (TC 2.A.14) The only characterized member of this family, from E. coli, appears to catalyze lactate:H+ uptake. Members of this family have 12 probable TMS. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]


Pssm-ID: 162041  Cd Length: 530  Bit Score: 266.18  E-value: 4.53e-82
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395    1 MSNGILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLL 79
Cdd:TIGR00795   3 VYDWLSAIVALLPILLFFFLLAVLKLKGYYAAPISVALSVIIALFYYKMPVIMTSAAFLYGFLYGLwPIAWIIIAAIFLY 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   80 NTLKHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFG 159
Cdd:TIGR00795  83 KLSVKSGAFEIIRSSILSISPDRRIQVLLIGFCFGAFLEGAAGFGTPVAITAAILVGLGFKPLYAAGLCLIANTAPVAFG 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  160 AVGTPIIVGINTGLDTASIgaqlveqgsswgqflqlITSQVAIIHATVGVVMPLIMVMMLTRFFGQEKSWkaglevlPFA 239
Cdd:TIGR00795 163 AVGIPIWAGAQATGLSALE-----------------ISSMTGFQLPFISLLIPFFLVFLMDGWKGIKETF-------PAV 218
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  240 IFGGLAFVLPYAATGIFLGPEFPSLLGGLIGLAIVTSAARfgFLVPKKTWDFAPAdkwpsewlgsvEMKLDELTAKPMSA 319
Cdd:TIGR00795 219 LVAGLSFAIPQFLSSNYLGPELPSILGALVSLVITALFLK--FWQPKEIFRFNGK-----------LDAGEVSAHHICKI 285
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  320 LRAWLPYVMVGALLVISRVFP-----EVGNALKAVVVNF-------------PDLLGEAGVSANFQPLYLPGGI--LVAV 379
Cdd:TIGR00795 286 VKAWSPFVLLTAFIVLWSIPPfkalfMKGGALIFSSFTFgspglsqhifklpPIVNQATNFPAVFKLLLIIATGtsILLA 365
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  380 VLATFFLHGMKARDLGKAVKESSSvllsagfvLLFTVPMVRILINSGVNGAELASMPILMAGWVAESvGGIYPLLAPSIG 459
Cdd:TIGR00795 366 AIVSFFILRVSISDAIGVFGETLK--------EMRLPILTIGMVLAFANVSNYSGMSKTLALALAHT-GLAFTFFSPFLG 436
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  460 ALGAFIAGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLY 539
Cdd:TIGR00795 437 WLGVFLTGSDTSSNLLFGSLQLLTAEQIGLPETLLLAANTVGGVMGKMISPQSIAIACAAVGLVGQESDLFRKTVKYSLI 516
                         570
                  ....*....|....
gi 490559395  540 YVLFTGIIAMIAIY 553
Cdd:TIGR00795 517 YAIIVGVVALLLAY 530
PRK10420 PRK10420
L-lactate permease; Provisional
7-555 1.37e-43

L-lactate permease; Provisional


Pssm-ID: 182445  Cd Length: 551  Bit Score: 163.09  E-value: 1.37e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   7 ALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLLNTLKHS 85
Cdd:PRK10420  18 SLIASLPILFFFFALIKLKLKGYVAASWTVAIALAVALLFYKMPVANALASVVYGFFYGLwPIAWIIIAAVFVYKISVKT 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  86 GGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGAVGTPI 165
Cdd:PRK10420  98 GQFDIIRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLCLIVNTAPVAFGAMGIPI 177
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 166 IV-GINTGLDTASIGAQlveqgsswgqflqlitsqvaiihatVGVVMPLIMVMMLTRFFGQEKSWKAGLEVLPFAIFGGL 244
Cdd:PRK10420 178 LVaGQVTGIDSFEIGQM-------------------------VGRQLPFLTIIVLFWIMAIMDGWRGVKETWPAVVVAGG 232
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 245 AFVLPYAATGIFLGPEFPSLLGGLIGLAIVTsaARFGFLVPKKTWDFAPADKwpsewlGSVEMKLDELTAKPMSALRAWL 324
Cdd:PRK10420 233 SFAIAQYLSSNFIGPELPDIISSLVSLVCLT--LFLKRWQPVRIFRFGDLGA------SQVDMTLAHTGYTAGQVLRAWS 304
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 325 PYVMVGALLVISRVFP-----EVGNALKAVVVNF------------PDLLGEAGVSA---NFQPLYLPG-GILVAVVLAT 383
Cdd:PRK10420 305 PFLFLTATVTLWSIPPfkalfASGGALYEWVINIpvpyldklvarmPPVVSEATAYAavyKFDWFSATGtAILFAALLSI 384
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 384 FFLHgMKARD----LGKAVKESSSVLLSAGFVLLFTVpmvrILINSGVNgaelASMPILMAgwvaeSVGGIYPLLAPSIG 459
Cdd:PRK10420 385 VWLK-MKPSDaistFGSTLKELALPIYSIGMVLAFAF----ISNYSGLS----STLALALA-----HTGHAFTFFSPFLG 450
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 460 ALGAFIAGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIWPMLY 539
Cdd:PRK10420 451 WLGVFLTGSDTSSNALFAALQATAAQQIGVSDVLLVAANTTGGVTGKMISPQSIAIACAAVGLVGKESDLFRFTVKHSLI 530
                        570
                 ....*....|....*.
gi 490559395 540 YVLFTGIIAMIAIYVL 555
Cdd:PRK10420 531 FTCMVGVITTLQAYVL 546
PRK09695 PRK09695
glycolate permease GlcA;
4-555 1.51e-35

glycolate permease GlcA;


Pssm-ID: 182032  Cd Length: 560  Bit Score: 140.58  E-value: 1.51e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395   4 GILALLAFSPILLAAILLIGLRWPAKHAMPLVYLVTAAVGLFAWDMTLNRVLASTLQGLLITL-GLLWIIFGAILLLNTL 82
Cdd:PRK09695  15 GLSALVALIPIIFFFVALAVLRLKGHVAGAITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLwPIAWIIVAAVFLYKLT 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395  83 KHSGGITAIRAGFTTISPDRRIQAIIIAWLFGCFIEGASGFGTPAAIAAPLLVAIGFPAMAAVLLGMLVQSTPVSFGAVG 162
Cdd:PRK09695  95 VASGQFDIIRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLCLIANTAPVAFGALG 174
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 163 TPIIV-GINTGLDTASIGAQlveqgsswgqflqlitsqvaiihatVGVVMPLIMVMMLTRFFGQEKSWKAGLEVLPFAIF 241
Cdd:PRK09695 175 VPILVaGQVTGIDPFHIGAM-------------------------AGRQLPFLSVLVPFWLVAMMDGWKGVKETWPAALV 229
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 242 GGLAFVLPYAATGIFLGPEFPSLLGGLIglAIVTSAARFGFLVPKKTWDFAPADKWPSEWLGSVEMKLDELTAKPM--SA 319
Cdd:PRK09695 230 AGGSFAVTQFFTSNYIGPELPDITSALV--SIVSLALFLKVWRPKNTETAISMGQSAGAMVVNKPSSGGPVPSEYSlgQI 307
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 320 LRAWLPYVMVGALLVISRVFP-----EVGNALKAVVVNF------PDLLGEAGVSAN---------FQPLYLPG-GILVA 378
Cdd:PRK09695 308 IRAWSPFLILTVLVTIWTMKPfkalfAPGGAFYSLVINFqiphlhQQVLKAAPIVAQptpmdavfkFDPLSAGGtAIFIA 387
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 379 VVLATFFLHGMKARDLGKAVKESSSV---LLSAGFVLLFTVpmvrILINSGVNgaelASMPILMAGwvaesVGGIYPLLA 455
Cdd:PRK09695 388 AIISIFILGVGIKKGIGVFAETLISLkwpILSIGMVLAFAF----VTNYSGMS----TTLALVLAG-----TGVMFPFFS 454
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490559395 456 PSIGALGAFIAGSNTVSNMMFSQFQFGVASSLGISSALIVSVQAIGAAAGNMVAIHNVVAASATVGLLGREGSTLRKTIW 535
Cdd:PRK09695 455 PFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMISPQSIAVACAATGMVGRESELFRYTVK 534
                        570       580
                 ....*....|....*....|
gi 490559395 536 PMLYYVLFTGIIAMIAIYVL 555
Cdd:PRK09695 535 HSLIFASVIGIITLLQAYVF 554
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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