|
Name |
Accession |
Description |
Interval |
E-value |
| PRK07049 |
PRK07049 |
cystathionine gamma-synthase family protein; |
1-427 |
0e+00 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 180809 [Multi-domain] Cd Length: 427 Bit Score: 880.55 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 1 MTAPHPSKTHIGNHALHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYVSGRKEPPEGRGAGLVYSRF 80
Cdd:PRK07049 1 MTAPHPSKTHIGNRELHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFRSAEDGRDFFDYVSGRKEPPAGEGAGLVYSRF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 81 NHPNSEIVEDRLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVGFADGVSET 160
Cdd:PRK07049 81 NHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLLAFVRPGDVILHSQPLYGGTETLLAKTFRNFGVGAVGFADGLSEA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 161 SVMAAAEEAMAKGRVSVILIETPANPTNSIVDIAMIGRVAEVIGKRQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLT 240
Cdd:PRK07049 161 AIGAAAEAAAAKGRVSLILIETPANPTNSLVDVAAVRRVADAIEARQGHRPIIACDNTLLGPVFQKPLEHGADLSVYSLT 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 241 KYVGGHSDLIAGAALGRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYL 320
Cdd:PRK07049 241 KYVGGHSDLVAGAVLGRKALIRQVRALRSAIGTQLDPHSCWMLGRSLETLVLRMERANRNARAVAEFLRDHPKVEKLHYL 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 321 PFSDPASAVGKVFAAQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVL 400
Cdd:PRK07049 321 PFLDPDSAYGAVYKRQCTGAGSTFSFDIKGGQAAAFRFLNALQIFKLAVSLGGTESLASHPASMTHSGVPADVRERIGVL 400
|
410 420
....*....|....*....|....*..
gi 490580875 401 DSTIRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:PRK07049 401 ESTIRLSIGIEHPDDLIADLAQALDAA 427
|
|
| MetC |
COG0626 |
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; ... |
16-427 |
5.00e-170 |
|
Cystathionine beta-lyase/cystathionine gamma-synthase [Amino acid transport and metabolism]; Cystathionine beta-lyase/cystathionine gamma-synthase is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 440391 [Multi-domain] Cd Length: 389 Bit Score: 481.86 E-value: 5.00e-170
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDyvsgrkeppeGRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:COG0626 1 MGPATRAVHAGRDPDPQTGAVSPPIYLTSTFVFPSAEALAARFA----------GEEGGYIYSRYGNPTRRALEEALAAL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRV 175
Cdd:COG0626 71 EGGEAALAFASGMAAISAVLLALLKAGDHVVASDDLYGGTRRLLDKVLARFGIE-VTFVDPTDLAAVEAAI-----RPNT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 176 SVILIETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL 255
Cdd:COG0626 145 KLVFLETPSNPTLEVVDIAAIAAIA------HAAGALLVVDNTFATPLLQRPLELGADIVVHSATKYLGGHSDVLGGAVV 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 256 GRKD-VMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVgkv 332
Cdd:COG0626 219 GRDEeLAERLRFLQNALGAVLSPFDAWLLLRGLKTLALRMERHCENALAVAEWLEAHPAVARVYYpgLP-SHPGHEL--- 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 FAAQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEH 412
Cdd:COG0626 295 AKRQMSGFGGMLSFELKGGREAARRFLDALKLFTLAVSLGGVESLITHPATMTHRSLPPEERAALGITDGLVRLSVGLED 374
|
410
....*....|....*
gi 490580875 413 PDDLIADLTLSLDQV 427
Cdd:COG0626 375 VDDLIADLEQALAAL 389
|
|
| CGS_like |
cd00614 |
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed ... |
34-425 |
2.12e-154 |
|
CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of antimicrobials and herbicides. This subgroup also includes cystathionine gamma-lyases (CGL), O-acetylhomoserine sulfhydrylases and O-acetylhomoserine thiol lyases. CGL's are very similar to CGS's. Members of this group are widely distributed among all three forms of life.
Pssm-ID: 99738 [Multi-domain] Cd Length: 369 Bit Score: 441.26 E-value: 2.12e-154
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 34 GAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAIST 113
Cdd:cd00614 1 GAVAPPIYQTSTFVFPSPAEAADLF----------ALREGGYIYSRIGNPTVDALEKKLAALEGGEAALAFSSGMAAIST 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 114 TLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRVSVILIETPANPTNSIVDI 193
Cdd:cd00614 71 VLLALLKAGDHVVASDDLYGGTYRLFERLLPKLGIE-VTFVDPDDPEALEAAI-----KPETKLVYVESPTNPTLKVVDI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 194 AMIGRVAevigKRQGhrPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR-KDVMKQVKALRGAIG 272
Cdd:cd00614 145 EAIAELA----HEHG--ALLVVDNTFATPYLQRPLELGADIVVHSATKYIGGHSDVIAGVVVGSgEALIQRLRFLRLALG 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 273 TQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKvfaAQCSGAGSTFSFDIVG 350
Cdd:cd00614 219 TILSPFDAWLLLRGLKTLPLRMERHSENALKVAEFLEKHPKVERVYYpgLP-SHPQHELAK---KQMSGYGGVFSFELKG 294
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490580875 351 GQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLD 425
Cdd:cd00614 295 GLEAAKKFLNALKLFSLAVSLGGVESLVEHPASMTHSQLPPEERAAAGITPGLVRLSVGIEDVEDLIADLEQALK 369
|
|
| Cys_Met_Meta_PP |
pfam01053 |
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and ... |
19-420 |
4.23e-122 |
|
Cys/Met metabolism PLP-dependent enzyme; This family includes enzymes involved in cysteine and methionine metabolism. The following are members: Cystathionine gamma-lyase, Cystathionine gamma-synthase, Cystathionine beta-lyase, Methionine gamma-lyase, OAH/OAS sulfhydrylase, O-succinylhomoserine sulfhydrylase All of these members participate is slightly different reactions. All these enzymes use PLP (pyridoxal-5'-phosphate) as a cofactor.
Pssm-ID: 395837 [Multi-domain] Cd Length: 376 Bit Score: 359.24 E-value: 4.23e-122
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAedgrdffdyvsgrkeppeGRGAGLVYSRFNHPNSEIVEDRLAVYERT 98
Cdd:pfam01053 1 DTLAVHAGQRPDPQTGAVSVPIYLTSTYVFDFA------------------GEEGGYDYSRSGNPTRDVLEERIAALEGG 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 99 ESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAeeamaKGRVSVI 178
Cdd:pfam01053 63 AAALAFSSGMAAITAAILALLKAGDHIVATDDLYGGTYRLFNKVLPRFGIEVT-FVDTSDPEDLEAAI-----KPNTKAV 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 179 LIETPANPTNSIVDIAMIGRVAevigKRQGhrPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR- 257
Cdd:pfam01053 137 YLETPTNPLLKVVDIEAIAKLA----KKHG--ILVVVDNTFASPYLQRPLDLGADIVVHSATKYIGGHSDVVGGVIVVNg 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 258 KDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKvfaA 335
Cdd:pfam01053 211 EELGKELYFLQNATGAVLSPFDAWLLLRGLKTLGLRMEQHQENAQKVAEFLESHPKVEKVYYpgLP-SHPGHELAK---R 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 336 QCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDD 415
Cdd:pfam01053 287 QMKGFGGMLSFELKGGLEAAKKFLDNLKLFSLAVSLGGVESLISHPATMTHASIPPEEREAAGITDDLIRLSVGIEDVDD 366
|
....*
gi 490580875 416 LIADL 420
Cdd:pfam01053 367 LIADL 371
|
|
| PRK06767 |
PRK06767 |
methionine gamma-lyase; Provisional |
17-427 |
8.41e-105 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 180685 [Multi-domain] Cd Length: 386 Bit Score: 315.63 E-value: 8.41e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYE 96
Cdd:PRK06767 5 HMETALIHHGYTSEEHKGSLTPPLFQTSTFTFETAQQGEASF----------AGVDPSYIYSRLGNPTVKLFEERMAVLE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 97 RTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAvGFADGVSETSVMAAAeeamaKGRVS 176
Cdd:PRK06767 75 GGEEALAFGSGMAAISATLIGFLKAGDHIICSNGLYGCTYGFLEVLEEKFMITH-SFCDMETEADIENKI-----RPNTK 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 177 VILIETPANPTNSIVDIAMIGRVAevigkRQGHRPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALG 256
Cdd:PRK06767 149 LIFVETPINPTMKLIDLKQVIRVA-----KRNGLLVIV-DNTFCSPYLQRPLELGCDAVVHSATKYIGGHGDVVAGVTIC 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 RKDVMKQV-KALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlpfsdPAsavGKVFAA 335
Cdd:PRK06767 223 KTRALAEKiRPMRKDIGGIMAPFDAWLLLRGLKTLAVRMDRHCDNAEKIVSFLKNHDAVEGVWY-----PE---GELASR 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 336 QCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDD 415
Cdd:PRK06767 295 QMKRGGGVISFSIKGGKEETQAFINDLHFITIAVSLGDTETLIQHPATMTHAAIPAELRQEMGIYDNLIRLSVGLESWED 374
|
410
....*....|..
gi 490580875 416 LIADLTLSLDQV 427
Cdd:PRK06767 375 IVSDLEQALKKI 386
|
|
| met_gam_lyase |
TIGR01328 |
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of ... |
17-427 |
5.26e-102 |
|
methionine gamma-lyase; This model describes a methionine gamma-lyase subset of a family of PLP-dependent trans-sulfuration enzymes. The member from the parasite Trichomonas vaginalis is described as catalyzing alpha gamma- and alpha-beta eliminations and gamma-replacement reactions on methionine, cysteine, and some derivatives. Likewise, the enzyme from Pseudomonas degrades cysteine as well as methionine. [Energy metabolism, Amino acids and amines]
Pssm-ID: 130395 [Multi-domain] Cd Length: 391 Bit Score: 308.74 E-value: 5.26e-102
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYE 96
Cdd:TIGR01328 3 TFATRAIHAGYPPKDQFGALTPPIYQTSTFVFDSCEQGGNRF----------AGQESGYIYSRLGNPTVSNLEGRIAFLE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 97 RTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRVS 176
Cdd:TIGR01328 73 GTEAAVATSSGMGAIAATLLTILKAGDHLISDECLYGCTFALLEHALTKFGIQ-VDFINMAIPEEVKAHI-----KDNTK 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 177 VILIETPANPTNSIVDIAMIGRVAevigKRQGHRPIIacDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALG 256
Cdd:TIGR01328 147 IVYFETPANPTMKLIDMERVCRDA----HSQGVKVIV--DNTFATPMLTNPVALGVDVVVHSATKYIGGHGDVVAGLICG 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 RKDVMKQVK--ALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFSDPASAvgKVFA 334
Cdd:TIGR01328 221 KAELLQQIRmvGIKDMTGSVISPFDAWLILRGLKTLNIRMKRHSENAMKVAEYLKSHPAVEKVYYPGFEDHPGH--DIAA 298
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 335 AQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPD 414
Cdd:TIGR01328 299 KQMRMGGGMITFELKGGFAGAKKLLNNLKLIRLAVSLGDAETLIQHPASMTHAVVPKEEREAAGITDGMIRLSVGLEDAD 378
|
410
....*....|...
gi 490580875 415 DLIADLTLSLDQV 427
Cdd:TIGR01328 379 DLIADLKQALDAL 391
|
|
| MET17 |
COG2873 |
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid ... |
13-427 |
7.60e-98 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent [Amino acid transport and metabolism]; O-acetylhomoserine/O-acetylserine sulfhydrylase, pyridoxal phosphate-dependent is part of the Pathway/BioSystem: Methionine biosynthesis
Pssm-ID: 442120 [Multi-domain] Cd Length: 428 Bit Score: 299.25 E-value: 7.60e-98
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 13 NHALHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYvsgrKEPpegrgaGLVYSRFNHPNSEIVEDRL 92
Cdd:COG2873 3 EKKYGFETLALHAGQEPDPTTGARAVPIYQTTSYVFDDAEHAADLFAL----KEP------GNIYTRIMNPTTDVLEKRI 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 93 AVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaK 172
Cdd:COG2873 73 AALEGGVAALATASGQAAITLAILNLAEAGDHIVASSSLYGGTYNLFAHTLPRLGIE-VRFVDPDDPEAFEAAI-----D 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 173 GRVSVILIETPANPTNSIVDIAMIGRVAevigkrqgHR---PIIaCDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDL 249
Cdd:COG2873 147 PNTKAIFGETIGNPALDVLDIEAIAEIA--------HEhgvPLI-VDNTFATPYLCRPIEHGADIVVHSATKYIGGHGTS 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 250 IAGAAL--GRKD-------------------------------VMK-QVKALRgAIGTQLDPHSCWMLGRSLETLQIRME 295
Cdd:COG2873 218 IGGVIVdgGNFDwaangkfpeltepdpsyhglvyteafgnaafITKaRVQLLR-DLGAALSPFNAFLLLQGLETLSLRME 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 296 RADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGG 373
Cdd:COG2873 297 RHVENALKVAEFLEAHPKVAWVNYpgLP-SHPYHELAQKYLPK--GAGGVLTFGLKGGREAGKKFIDSLKLFSHLANIGD 373
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 490580875 374 TESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:COG2873 374 AKSLVIHPASTTHSQLSEEEQAAAGVTPDLIRLSVGIEDIDDIIADLDQALAAA 427
|
|
| PRK07503 |
PRK07503 |
methionine gamma-lyase; Provisional |
20-426 |
2.59e-96 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 181005 [Multi-domain] Cd Length: 403 Bit Score: 294.40 E-value: 2.59e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 20 TQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYERTE 99
Cdd:PRK07503 12 TRAIHHGYDPLDHGGALVPPVYLTATFAFPTAEYGAECF----------AGEEEGHFYSRISNPTLALLEQRMASLEGGE 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 100 SCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAvgfaDGVSETSVMAAAEEAMAKGRVsvIL 179
Cdd:PRK07503 82 AAVALASGMGAITATLWTLLRPGDEVIVDQTLYGCTFAFLHHGLGEFGVTV----RHVDLTDPAALKAAISDKTRM--VY 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 180 IETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKD 259
Cdd:PRK07503 156 FETPANPNMRLVDIAAVAEIA------HGAGAKVVVDNTYCTPYLQRPLELGADLVVHSATKYLGGHGDITAGLVVGGKA 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 260 VMKQVK--ALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFsdPASAVGKVFAAQC 337
Cdd:PRK07503 230 LADRIRleGLKDMTGAVMSPFDAFLLMRGLKTLALRMDRHCASAQAVAEWLARHPAVELVHYPGL--PSFAQHALAQRQM 307
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 338 SGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLI 417
Cdd:PRK07503 308 ALPGGMIAFELKGGIAAGRRFMNALQLFARAVSLGDAESLAQHPASMTHSTYTPEERAEHGISEGLVRLSVGLEDVADIL 387
|
....*....
gi 490580875 418 ADLTLSLDQ 426
Cdd:PRK07503 388 ADLAQALDA 396
|
|
| PRK06234 |
PRK06234 |
methionine gamma-lyase; Provisional |
34-427 |
6.97e-94 |
|
methionine gamma-lyase; Provisional
Pssm-ID: 168478 [Multi-domain] Cd Length: 400 Bit Score: 288.26 E-value: 6.97e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 34 GAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAIST 113
Cdd:PRK06234 25 GSLATPIYQTSTFIFDSAEQGGRRF----------AGEESGYIYSRLGNPTSTEVENKLALLEGGEAAVVAASGMGAISS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 114 TLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRVSVILIETPANPTNSIVDI 193
Cdd:PRK06234 95 SLWSALKAGDHVVASDTLYGCTFALLNHGLTRYGVE-VTFVDTSNLEEVRNAL-----KANTKVVYLETPANPTLKVTDI 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 194 AMIGRVAevigkrqgHRPIIAC----DNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKDVMKQVK--AL 267
Cdd:PRK06234 169 KAISNIA--------HENNKEClvfvDNTFCTPYIQRPLQLGADVVVHSATKYLNGHGDVIAGFVVGKEEFINQVKlfGI 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 268 RGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKvfaAQCSGAGSTFS 345
Cdd:PRK06234 241 KDMTGSVIGPFEAFLIIRGMKTLQIRMEKHCKNAMKVAKFLESHPAVEKVYYpgLE-SFEYYELAK---KQMSLPGAMIS 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 346 FDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLD 425
Cdd:PRK06234 317 FELKGGVEEGKVVMNNVKLATLAVSLGDAETLIQHPASMTHSPYTAEERKEAGISDGLVRLSVGLEDVDDIIADLKQALD 396
|
..
gi 490580875 426 QV 427
Cdd:PRK06234 397 LI 398
|
|
| PRK08133 |
PRK08133 |
O-succinylhomoserine sulfhydrylase; Validated |
39-425 |
3.54e-87 |
|
O-succinylhomoserine sulfhydrylase; Validated
Pssm-ID: 181244 [Multi-domain] Cd Length: 390 Bit Score: 270.72 E-value: 3.54e-87
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 39 PVFLTSTFVFKSAEDGRDFFdyvsGRKEPpegrgaGLVYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAISTTLFAF 118
Cdd:PRK08133 27 ALFLTSSFVFESAAEAAARF----AGEEP------GNIYSRFTNPTVTMFQERLAALEGAEACVATASGMAAILAVVMAL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 119 VRPGDTVLHSQPLYGGTETLLAKTFHNFGVsAVGFadgVSETSVMAAAEEAMAKGRVsvILIETPANPTNSIVDIAMIGR 198
Cdd:PRK08133 97 LQAGDHVVSSRSLFGSTVSLFEKIFARFGI-ETTF---VDLTDLDAWRAAVRPNTKL--FFLETPSNPLTELADIAALAE 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 199 VAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKDVMKQV-KALRGAiGTQLDP 277
Cdd:PRK08133 171 IA------HAAGALLVVDNCFCTPALQQPLKLGADVVIHSATKYLDGQGRVLGGAVVGSKELMEEVfGFLRTA-GPTLSP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 278 HSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKvfaAQCSGAGSTFSFDIVGGQAAS 355
Cdd:PRK08133 244 FNAWVFLKGLETLSLRMEAHSANALALAEWLEAHPGVERVFYpgLP-SHPQHELAK---RQQKGGGAIVSFEVKGGREAA 319
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 356 FKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLD 425
Cdd:PRK08133 320 WRVIDATRLISITANLGDTKTTITHPATTTHGRLSPEARAAAGITEGLIRVAVGLEDVADIKADLARGLA 389
|
|
| OAH_OAS_sulfhy |
TIGR01326 |
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism ... |
17-424 |
1.24e-86 |
|
OAH/OAS sulfhydrylase; This model describes a distinct clade of the Cys/Met metabolism pyridoxal phosphate-dependent enzyme superfamily. Members include examples of OAH/OAS sulfhydrylase, an enzyme with activity both as O-acetylhomoserine (OAH) sulfhydrylase (EC 2.5.1.49) and O-acetylserine (OAS) sulphydrylase (EC 2.5.1.47). An alternate name for OAH sulfhydrylase is homocysteine synthase. This model is designated subfamily because it may or may not have both activities. [Amino acid biosynthesis, Aspartate family, Amino acid biosynthesis, Serine family]
Pssm-ID: 273555 [Multi-domain] Cd Length: 418 Bit Score: 270.00 E-value: 1.24e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYvsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVYE 96
Cdd:TIGR01326 1 HFETLQLHAGQEPDPTTGSRAVPIYQTTSYVFDSTEHAAALFGL----------QEPGNIYSRLMNPTTDVLEQRIAALE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 97 RTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRVS 176
Cdd:TIGR01326 71 GGVAALAVASGQAAITYAILNLAGAGDNIVSSSYLYGGTYNLFSHTLKRLGIE-VRFVDPDDPESLEKAI-----DENTK 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 177 VILIETPANPTNSIVDIAMIGRVAevigKRQGhRPIIaCDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALG 256
Cdd:TIGR01326 145 AVFAETIGNPQINVLDIEAIAEVA----HRHG-IPLI-VDNTFATPYLCRPIKHGADIVVHSATKYIGGHGTAIGGVIVD 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 RKD---------------------------------VMKQVKALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARL 303
Cdd:TIGR01326 219 GGKfdwnngrfplfttpdpsyhglvftetlgnpafiLKARVQLLRD-LGAALSPFNAFLLLQGLETLSLRMERHVENALK 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 304 VAEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHP 381
Cdd:TIGR01326 298 VAEFLESHPDVAWVNYpgLA-SHPHHALAKKYLPK--GFGAVLSFEIKGGREAGKKFIDALKLASHLANVGDAKSLVIHP 374
|
410 420 430 440
....*....|....*....|....*....|....*....|...
gi 490580875 382 ATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSL 424
Cdd:TIGR01326 375 ASTTHSQLSEEEQLKAGVTPGLIRLSVGIENIDDIIADLEQAL 417
|
|
| PRK07811 |
PRK07811 |
cystathionine gamma-synthase; Provisional |
14-426 |
2.21e-85 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 236104 [Multi-domain] Cd Length: 388 Bit Score: 265.74 E-value: 2.21e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 14 HALHPETQMLNYGYDPELSEGAVKPPVFLTSTFvfksAEDGrdffdyvsgrkepPEGRGAGLVYSRFNHPNSEIVEDRLA 93
Cdd:PRK07811 9 ANQGFATRAIHAGYEPDPATGAVNPPIYASSTF----AQDG-------------VGGLRGGYEYARTGNPTRTALEEQLA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 94 VYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGV--SAVGFADgvsetsvmAAAEEAMA 171
Cdd:PRK07811 72 ALEGGAYGRAFSSGMAATDCLLRAVLRPGDHIVIPNDAYGGTFRLIDKVFTRWGVeyTPVDLSD--------LDAVRAAI 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 172 KGRVSVILIETPANPTNSIVDIAMIGRVAEvigkrqGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIA 251
Cdd:PRK07811 144 TPRTKLIWVETPTNPLLSITDIAALAELAH------DAGAKVVVDNTFASPYLQQPLALGADVVVHSTTKYIGGHSDVVG 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 252 GAAL-GRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASA 328
Cdd:PRK07811 218 GALVtNDEELDEAFAFLQNGAGAVPGPFDAYLTLRGLKTLAVRMDRHSENAEAVAEFLAGHPEVSTVLYpgLP-SHPGHE 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 329 VGkvfAAQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSG-------VPADVrqrigvld 401
Cdd:PRK07811 297 VA---ARQMRGFGGMVSVRLAGGEEAARDFCARTKVFTLAESLGGVESLIEHPSAMTHAStagsqleVPDDL-------- 365
|
410 420
....*....|....*....|....*
gi 490580875 402 stIRLSIGIEHPDDLIADLTLSLDQ 426
Cdd:PRK07811 366 --VRLSVGIEDVADLLADLEQALGQ 388
|
|
| O_succ_thio_ly |
TIGR02080 |
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, ... |
18-424 |
1.26e-84 |
|
O-succinylhomoserine (thiol)-lyase; This family consists of O-succinylhomoserine (thiol)-lyase, one of three different enzymes designated cystathionine gamma-synthase and involved in methionine biosynthesis. In all three cases, sulfur is added by transsulfuration from Cys to yield cystathionine rather than by a sulfhydrylation step that uses H2S directly and bypasses cystathionine. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 131135 Cd Length: 382 Bit Score: 263.58 E-value: 1.26e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 18 PETQMLNYGYDPELSEGAVKPPVFLTSTFVFksaedgrdffdyvSGRKEPPEgrgagLVYSRFNHPNSEIVEDRLAVYER 97
Cdd:TIGR02080 4 QATIAVRSGLNSDTQYGCVVPPIYLSTTYNF-------------TGFNEPRA-----YDYSRSGNPTRDLLQQALAELEG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLaKTFHNFGVSAVGFADGVSETSVMAAAeeamaKGRVSV 177
Cdd:TIGR02080 66 GAGAVVTNTGMSAIHLVTTALLGPDDLLVAPHDCYGGTYRLL-NALAKKGCFRVLFVDQGDEQALRAAL-----AQKPKL 139
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 178 ILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR 257
Cdd:TIGR02080 140 VLIETPSNPLLRVVDIAKICHLAKAVGA------VVVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVIAGAVIAK 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 258 -KDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFSDPASAvgKVFAAQ 336
Cdd:TIGR02080 214 dPQVAEELAWWANNLGVTGGAFDSYLTLRGLRTLVARMRLQQRNAQAIVEYLQTQPLVKKIYYPGLPDHPGH--EIAARQ 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 337 CSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDL 416
Cdd:TIGR02080 292 QKGFGAMLSFELKGGEQTVRRFLGGLSLFTLAESLGGVESLIAHPATMTHAAMGPEARAEAGISDTLLRLSVGLEDADDL 371
|
....*...
gi 490580875 417 IADLTLSL 424
Cdd:TIGR02080 372 IADLEQGL 379
|
|
| PRK08574 |
PRK08574 |
cystathionine gamma-synthase family protein; |
26-427 |
3.17e-82 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236298 [Multi-domain] Cd Length: 385 Bit Score: 257.69 E-value: 3.17e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 26 GYDPELSEGAVKPPVFLTSTFvfksAEDGRDFFDyvsgrkeppeGRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFS 105
Cdd:PRK08574 10 GYRGSDPYGSLQPPIYLTALF----RQEGEAYPS----------DRGFDLKYSREENPTLRPLEEALAKLEGGVDALAFN 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 106 SGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLaKTFHNFGVSAV-GFADgvSETSVMAAAeeamaKGRVSVILIETPA 184
Cdd:PRK08574 76 SGMAAISTLFFSLLKAGDRVVLPMEAYGTTLRLL-KSLEKFGVKVVlAYPS--TEDIIEAIK-----EGRTKLVFIETMT 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 185 NPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAA-LGRKDVMKQ 263
Cdd:PRK08574 148 NPTLKVIDVPEVAKAAKELGA------ILVVDNTFATPLLYRPLRHGADFVVHSLTKYIAGHNDVVGGVAvAWSGEFLEE 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 264 VKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGK-VFAAQCSGA 340
Cdd:PRK08574 222 LWEWRRRLGTIMQPFEAYLVLRGLKTLEVRFERQCRNAMAIAEFLSEHPKVAEVYYpgLP-SDPYHGVAKrLFGKDLYGG 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 341 gsTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADL 420
Cdd:PRK08574 301 --VVSFRVKGGRDAVLKFLRSLKLIKPSPSLGGVESLATYPVKSAASPIPEEDRKALGITEDLVRLSVGLEDVEDLIEDL 378
|
....*..
gi 490580875 421 TLSLDQV 427
Cdd:PRK08574 379 DQALGSI 385
|
|
| PRK06460 |
PRK06460 |
hypothetical protein; Provisional |
20-424 |
1.04e-79 |
|
hypothetical protein; Provisional
Pssm-ID: 235807 [Multi-domain] Cd Length: 376 Bit Score: 250.90 E-value: 1.04e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 20 TQMLNYGYDPElsEGAVKPPVFLTSTFVFKSAEDGRdffdyvsgrkeppegrgaglvYSRFNHPNSEIVEDRLAVYERTE 99
Cdd:PRK06460 5 TRTVREDIDEA--TGAITTPIYQTTAYHYPEGEKYR---------------------YSREANPTVLELTKKIVELENAE 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 100 SCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAvgfadGVSETSVMAAAEEAMAKgRVSVIL 179
Cdd:PRK06460 62 MGVAFSSGMGAISTTALALLKPGNSVLVHRDMFGRSYRFFTDYLKNWGVNV-----DASNPGSDNIIEKAKSK-RYDVVF 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 180 IETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKD 259
Cdd:PRK06460 136 VENITNPLLRVVDITELSKVCKENGS------ILIVDATFSTPINQKPLELGADIVVHSASKFLAGHNDVIAGLAAGYGK 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 260 VMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY-----LPFSDPASAVGKvfa 334
Cdd:PRK06460 210 LLNVIDQMRRTLGTSLDPHAAYLTLRGIKTLKIRMDVINRNAEQIAEFLEGHPKVVKVYYpglksHVDYEIARRVLK--- 286
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 335 aqcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPD 414
Cdd:PRK06460 287 ----GFGGVLSFEVNGGQESALKVMKSLKLIIPAQTLGGVNSVISHPATMSHRTLSLEERKIVGITDSLLRLSVGIEDVN 362
|
410
....*....|
gi 490580875 415 DLIADLTLSL 424
Cdd:PRK06460 363 DLIEDLDRAL 372
|
|
| PRK08249 |
PRK08249 |
cystathionine gamma-synthase family protein; |
10-427 |
1.79e-79 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 236202 [Multi-domain] Cd Length: 398 Bit Score: 250.81 E-value: 1.79e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 10 HIGNHALHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFksaEDGRDFFDYVSGRKEppegrgaGLVYSRFNHPNSEIVE 89
Cdd:PRK08249 1 KMDFNNAGVGTKAVWAGEKEYLPYGATQVPVVLSVAYGY---DDIDEWYDVALGKKP-------GHIYSRNTNPTVQAFE 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 90 DRLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgfadgVSETSVMAAAEEA 169
Cdd:PRK08249 71 EKVRILEGAEAATAFSTGMAAISNTLYTFLKPGDRVVSIKDTYGGTNKIFTEFLPRMGVDVT-----LCETGDHEQIEAE 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 170 MAKGrVSVILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDL 249
Cdd:PRK08249 146 IAKG-CDLLYLETPTNPTLKIVDIERLAAAAKKVGA------LVVVDNTFATPINQNPLALGADLVIHSATKFLSGHADA 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 250 IAGAALGRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPAS 327
Cdd:PRK08249 219 LGGVVCGSKELMEQVYHYREINGATMDPMSAYLILRGMKTLKLRVRQQQESAMALAKYLQTHPKVEAVYYpgLE-THPNH 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 328 AVGKvfaAQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLS 407
Cdd:PRK08249 298 EIAK---AQMRGFGGILSFVLKGGMDTVKRLLPKLRYAHRAANLGAVETIYGPARTTSHVENTLEERAALGIPEGLVRIS 374
|
410 420
....*....|....*....|
gi 490580875 408 IGIEHPDDLIADLTLSLDQV 427
Cdd:PRK08249 375 VGIEDTEDLIADLEQAFAHL 394
|
|
| PRK07671 |
PRK07671 |
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase; |
16-425 |
2.45e-79 |
|
bifunctional cystathionine gamma-lyase/homocysteine desulfhydrase;
Pssm-ID: 181076 [Multi-domain] Cd Length: 377 Bit Score: 250.03 E-value: 2.45e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:PRK07671 1 MRAKTKLIHGGIIGDPSTGAVSVPIYQVSTY------------------KQEAVGKHQGYEYSRTGNPTRAALEELIAVL 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAISTTLFAFvRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAeeamaKGRV 175
Cdd:PRK07671 63 EGGHAGFAFGSGMAAITAVMMLF-SSGDHVILTDDVYGGTYRVMTKVLNRFGIEHT-FVDTSNLEEVEEAI-----RPNT 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 176 SVILIETPANPTNSIVDIAMIGRVAevigKRQGHRPIIacDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAG-AA 254
Cdd:PRK07671 136 KAIYVETPTNPLLKITDIKKISTIA----KEKGLLTIV--DNTFMTPYWQSPISLGADIVLHSATKYLGGHSDVVAGlVV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 255 LGRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKv 332
Cdd:PRK07671 210 VNSPELAEDLHFVQNSTGGILGPQDSWLLLRGLKTLGIRMEEHETNSRAIAEFLNNHPAVNKVYYpgLP-SHPNHELAK- 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 faAQCSGAGSTFSFDiVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEH 412
Cdd:PRK07671 288 --EQANGFGGMISFD-VGSEETANKVLERLQYFTLAESLGAVESLISIPSQMTHASIPADRRKELGITDGLIRISVGIED 364
|
410
....*....|...
gi 490580875 413 PDDLIADLTLSLD 425
Cdd:PRK07671 365 GEDLIEDLAQALA 377
|
|
| PRK08247 |
PRK08247 |
methionine biosynthesis PLP-dependent protein; |
17-427 |
2.85e-78 |
|
methionine biosynthesis PLP-dependent protein;
Pssm-ID: 181320 [Multi-domain] Cd Length: 366 Bit Score: 246.92 E-value: 2.85e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLNYGYDPELSEGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVYE 96
Cdd:PRK08247 4 TIETKLAQIGNRSDERTGTVNPPVYFSTAY------------------RHEGIGESTGFDYSRTGNPTRGVLEQAIADLE 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 97 RTESCALFSSGMSAISTtLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAEEamakgRVS 176
Cdd:PRK08247 66 GGDQGFACSSGMAAIQL-VMSLFRSGDELIVSSDLYGGTYRLFEEHWKKWNVRFV-YVNTASLKAIEQAITP-----NTK 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 177 VILIETPANPTNSIVDIAMIGRVAevigKRQGHRPIIacDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALG 256
Cdd:PRK08247 139 AIFIETPTNPLMQETDIAAIAKIA----KKHGLLLIV--DNTFYTPVLQRPLEEGADIVIHSATKYLGGHNDVLAGLVVA 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 R-KDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlpfsdpasavgkvfaa 335
Cdd:PRK08247 213 KgQELCERLAYYQNAAGAVLSPFDSWLLIRGMKTLALRMRQHEENAKAIAAFLNEQPGVTDVLY---------------- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 336 qcSGAGSTFSFDIvggQAASF--KFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHP 413
Cdd:PRK08247 277 --PGRGGMLSFRL---QDEEWvnPFLKSLKLITFAESLGGVESFITYPATQTHADIPEEIRIANGVCNRLLRFSVGIENV 351
|
410
....*....|....
gi 490580875 414 DDLIADLTLSLDQV 427
Cdd:PRK08247 352 EDLIADLKQAFKQV 365
|
|
| PRK08064 |
PRK08064 |
cystathionine beta-lyase MetC; |
19-427 |
9.08e-77 |
|
cystathionine beta-lyase MetC;
Pssm-ID: 236146 [Multi-domain] Cd Length: 390 Bit Score: 243.91 E-value: 9.08e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFvfkSAEDGRDFFDYVsgrkeppegrgaglvYSRFNHPNSEIVEDRLAVYERT 98
Cdd:PRK08064 8 DTLLLHNQYKHDKQTGAVNVPIYHASTF---HQFDFDTFGKYD---------------YSRSGNPTREALEDIIAELEGG 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 99 ESCALFSSGMSAISTTlFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAeeamaKGRVSVI 178
Cdd:PRK08064 70 TKGFAFASGMAAISTA-FLLLSKGDHVLISEDVYGGTYRMITEVLSRFGIEHT-FVDMTNLEEVAQNI-----KPNTKLF 142
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 179 LIETPANPTNSIVDIAMIGRVAEVIGkrqghrPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAG-AALGR 257
Cdd:PRK08064 143 YVETPSNPLLKVTDIRGVVKLAKAIG------CLTFVDNTFLTPLLQKPLDLGADVVLHSATKFLAGHSDVLAGlAVVKD 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 258 KDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFSDPASAVgkVFAAQC 337
Cdd:PRK08064 217 EELAQKLYFLQNSFGAVLGVQDCWLVLRGLKTLHVRLEHSSETANKIALYLQEHPKVQNVYYPGLQTHLGFD--IQQSQA 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 338 SGAGSTFSFDIvGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLI 417
Cdd:PRK08064 295 TSAGAVLSFTL-QSEEAVRQFVSHVKLPVFAVSLGAVESILSYPAKMSHAAMPKEERDERGITDGLLRLSVGLENVDDLI 373
|
410
....*....|
gi 490580875 418 ADLTLSLDQV 427
Cdd:PRK08064 374 ADFEQALSYV 383
|
|
| cysta_beta_ly_E |
TIGR01329 |
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase ... |
18-426 |
1.60e-74 |
|
cystathionine beta-lyase, eukaryotic; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys.
Pssm-ID: 273557 [Multi-domain] Cd Length: 378 Bit Score: 237.42 E-value: 1.60e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 18 PETQMLNYG--YDPElseGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:TIGR01329 1 LSTLLVNTDnkNDPY---DASSMPIYQTATF------------------KQPLAIENGPYDYTRSGNPTRTALESLLAKL 59
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAISTtLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAEEamakgRV 175
Cdd:TIGR01329 60 DKADRAFAFSSGMAALDV-ITRLLNNGDEIIAGDDLYGGTDRLLTQVVPRSGVVVV-HVDTTDLDKVKAALGP-----KT 132
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 176 SVILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA-A 254
Cdd:TIGR01329 133 KLVLLESPTNPLQKIVDIRKISEMAHAQNA------LVVVDNTMMSPLLCNPLELGADIVYHSATKFLAGHSDVMAGVlA 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 255 LGRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKV 332
Cdd:TIGR01329 207 VKGEEIAKKVYFLQNSTGSGLAPFDCWLLLRGIKTLAIRIEKQQENARAIAMFLSTHPRVKKVRYagLP-SHPGFHLHFS 285
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 FAaqcSGAGSTFSFdIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEH 412
Cdd:TIGR01329 286 QA---KGAGSVLSF-ETGSVALSKRLVEATKLFSITVSFGSVNSLISMPCFMSHASIPAEVREERGLPEDLVRLSVGIED 361
|
410
....*....|....
gi 490580875 413 PDDLIADLTLSLDQ 426
Cdd:TIGR01329 362 VDDLISDLDIAFVT 375
|
|
| PRK07810 |
PRK07810 |
O-succinylhomoserine sulfhydrylase; Provisional |
16-424 |
5.86e-72 |
|
O-succinylhomoserine sulfhydrylase; Provisional
Pssm-ID: 236103 [Multi-domain] Cd Length: 403 Bit Score: 231.55 E-value: 5.86e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQ-----MLNYGYDpELSEgavkpPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVED 90
Cdd:PRK07810 14 VSQATIgvrggLLRSGFE-ETAE-----ALYLTSGYVYESAAAAEAAF----------TGELDRFVYSRYGNPTVSMFEE 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 91 RLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVS----ETSVMAAA 166
Cdd:PRK07810 78 RLRLIEGAEACFATASGMSAVFTALGALLGAGDRLVAARSLFGSCFVVCNEILPRWGVETV-FVDGEDlsqwEEALSVPT 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 167 eeamakgrvSVILIETPANPTNSIVDIAMIGRVAEVIGKRqghrpiIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGH 246
Cdd:PRK07810 157 ---------QAVFFETPSNPMQSLVDIAAVSELAHAAGAK------VVLDNVFATPLLQRGLPLGADVVVYSGTKHIDGQ 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 247 SDLIAGAALGRKDVMK-QVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlPF--S 323
Cdd:PRK07810 222 GRVLGGAILGDREYIDgPVQKLMRHTGPALSAFNAWVLLKGLETLALRVRHSNASALRIAEFLEGHPAVRWVRY-PFlpS 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 324 DPASAVGKvfaAQCSGAGSTFSFDI----VGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGV 399
Cdd:PRK07810 301 HPQYDLAK---RQMSGGGTVVTFELdapeDAAKKRAFEVLDKLRVIDISNNLGDAKSLITHPATTTHRAMGPEGRAAIGL 377
|
410 420
....*....|....*....|....*
gi 490580875 400 LDSTIRLSIGIEHPDDLIADLTLSL 424
Cdd:PRK07810 378 GDGVVRLSVGLEDTDDLIADLDRAL 402
|
|
| PRK08045 |
PRK08045 |
cystathionine gamma-synthase; Provisional |
34-420 |
1.08e-71 |
|
cystathionine gamma-synthase; Provisional
Pssm-ID: 169194 [Multi-domain] Cd Length: 386 Bit Score: 230.55 E-value: 1.08e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 34 GAVKPPVFLTSTFvfksaedgrDFFDYVSGRKEPpegrgaglvYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAIST 113
Cdd:PRK08045 21 GCVVPPIHLSSTY---------NFTGFNEPRAHD---------YSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHL 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 114 TLFAFVRPGDTVLHSQPLYGGTETLLaKTFHNFGVSAVGFADGVSETSVMAAAEEamakgRVSVILIETPANPTNSIVDI 193
Cdd:PRK08045 83 VTTVFLKPGDLLVAPHDCYGGSYRLF-DSLAKRGCYRVLFVDQGDEQALRAALAE-----KPKLVLVESPSNPLLRVVDI 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 194 AMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR-KDVMKQVKALRGAIG 272
Cdd:PRK08045 157 AKICHLAREAGA------VSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKdPDVVTELAWWANNIG 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 273 TQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlPfSDPASAVGKVFAAQCSGAGSTFSFDIVGGQ 352
Cdd:PRK08045 231 VTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYH-P-SLPENQGHEIAARQQKGFGAMLSFELDGDE 308
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490580875 353 AASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADL 420
Cdd:PRK08045 309 QTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADL 376
|
|
| PRK07504 |
PRK07504 |
O-succinylhomoserine sulfhydrylase; Reviewed |
17-427 |
2.93e-71 |
|
O-succinylhomoserine sulfhydrylase; Reviewed
Pssm-ID: 168979 [Multi-domain] Cd Length: 398 Bit Score: 229.64 E-value: 2.93e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLN-------YGydpELSEGavkppVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVE 89
Cdd:PRK07504 10 RPATRLVHsgtlrsqFG---ETSEA-----LFLTQGFVYDTAEAAEARF----------KGEDPGFIYSRYSNPTVDMFE 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 90 DRLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGG----TETLLAKtfhnFGVSAVgFADGVSetsvmAA 165
Cdd:PRK07504 72 KRMCALEGAEDARATASGMAAVTAAILCQVKAGDHVVAARALFGScryvVETLLPR----YGIEST-LVDGLD-----LD 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 166 AEEAMAKGRVSVILIETPANPTNSIVDIAMIGRVAEVIGKRqghrpiIACDNTLLGPVFQRPIEHGADISLYSLTKYVGG 245
Cdd:PRK07504 142 NWEKAVRPNTKVFFLESPTNPTLEVIDIAAVAKIANQAGAK------LVVDNVFATPLFQKPLELGAHIVVYSATKHIDG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 246 HSDLIAGAALGRK--------DVMKQVkalrgaiGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKI 317
Cdd:PRK07504 216 QGRCLGGVVLSDKawieehlqDYFRHT-------GPSLSPFNAWTLLKGLETLPVRVRQQTESAAAIADFLAGHPKVARV 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 318 HYLPFSDPASAVgkVFAAQCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRI 397
Cdd:PRK07504 289 IYPGRADHPQAD--IIAKQMTGGSTLVAFELKGGKEAAFRFLNALKIVRISNNLGDAKSLITHPATTTHKNLSPEARAEL 366
|
410 420 430
....*....|....*....|....*....|
gi 490580875 398 GVLDSTIRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:PRK07504 367 GISEGFLRLSAGLEDTDDLIEDLAAALKKV 396
|
|
| PRK08776 |
PRK08776 |
O-succinylhomoserine (thiol)-lyase; |
17-426 |
3.23e-70 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181554 [Multi-domain] Cd Length: 405 Bit Score: 227.18 E-value: 3.23e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 17 HPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFfdyvsgrkeppegrgaglVYSRFNHPNSEIVEDRLAVYE 96
Cdd:PRK08776 12 SAATAAVRAGIDRDTAYGAVTPPIVLSSNFSFDGFGNKRQY------------------DYTRSGNPTRDLLGEALAELE 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 97 RTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETL---LAKTFHnFGVSAVGFADGVSETSVMAAAEeamakg 173
Cdd:PRK08776 74 GGAGGVITATGMGAINLVLNALLQPGDTLVVPHDAYGGSWRLfnaLAKKGH-FALITADLTDPRSLADALAQSP------ 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 174 rvSVILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA 253
Cdd:PRK08776 147 --KLVLIETPSNPLLRITDLRFVIEAAHKVGA------LTVVDNTFLSPALQKPLEFGADLVLHSTTKYINGHSDVVGGA 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 254 ALGRK-DVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFsdpASAVGKV 332
Cdd:PRK08776 219 VVARDaELHQQLVWWANALGLTGSPFDAFLTLRGLRTLDARLRVHQENADAIAALLDGHAAVNQVYYPGL---ASHPGHA 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 FAA-QCSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIE 411
Cdd:PRK08776 296 LAArQQKGFGAMLSFELEGGEAAVRAFVDGLRYFTLAESLGGVESLIAHPASMTHAAMTAEARAAAGISDGLLRLSVGIE 375
|
410
....*....|....*
gi 490580875 412 HPDDLIADLTLSLDQ 426
Cdd:PRK08776 376 SAEDLLIDLRAGLAR 390
|
|
| PLN02509 |
PLN02509 |
cystathionine beta-lyase |
20-424 |
3.88e-70 |
|
cystathionine beta-lyase
Pssm-ID: 178125 [Multi-domain] Cd Length: 464 Bit Score: 228.76 E-value: 3.88e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 20 TQMLNY--GYDPElseGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PLN02509 89 TLLVNLdnKFDPF---DAMSTPLYQTATF------------------KQPSAIENGPYDYTRSGNPTRDALESLLAKLDK 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFaFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSavgfadgVSETSVMAAAEEAMAKG-RVS 176
Cdd:PLN02509 148 ADRAFCFTSGMAALSAVTH-LIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVV-------VKRVNTTNLDEVAAAIGpQTK 219
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 177 VILIETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA-AL 255
Cdd:PLN02509 220 LVWLESPTNPRQQISDIRKIAEMA------HAQGALVLVDNSIMSPVLSRPLELGADIVMHSATKFIAGHSDVMAGVlAV 293
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 256 GRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFSD-PASavgKVFA 334
Cdd:PLN02509 294 KGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDhPGH---HLHF 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 335 AQCSGAGSTFSFdIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPD 414
Cdd:PLN02509 371 SQAKGAGSVFSF-ITGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVD 449
|
410
....*....|
gi 490580875 415 DLIADLTLSL 424
Cdd:PLN02509 450 DLISDLDIAF 459
|
|
| PRK06176 |
PRK06176 |
cystathionine gamma-synthase; |
16-427 |
1.15e-69 |
|
cystathionine gamma-synthase;
Pssm-ID: 180443 [Multi-domain] Cd Length: 380 Bit Score: 225.16 E-value: 1.15e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:PRK06176 1 MRMQTKLIHGGISEDTTTGAVSVPIYQTSTY------------------RQDAIGRPKGYEYSRSGNPTRFALEELIADL 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAISTtLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgfadgVSETSvMAAAEEAMAKGRV 175
Cdd:PRK06176 63 EGGVKGFAFASGLAGIHA-VFSLFQSGDHVLLGDDVYGGTFRLFDKVLVKNGLSCT-----IIDTS-DLSQIKKAIKPNT 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 176 SVILIETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL 255
Cdd:PRK06176 136 KALYLETPSNPLLKITDLAQCASVA------KDHGLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVT 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 256 GRKDVMKQ-VKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKv 332
Cdd:PRK06176 210 TNNEALAQeIAFFQNAIGGVLGPQDSWLLQRGIKTLGLRMEAHQKNALCVAEFLEKHPKVEKVYYpgLP-THPNHELAK- 287
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 faAQCSGAGSTFSFDIVGGQAASfKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEH 412
Cdd:PRK06176 288 --KQMRGFSGMLSFTLKNDSEAV-AFVESLKLFILGESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEH 364
|
410
....*....|....*
gi 490580875 413 PDDLIADLTLSLDQV 427
Cdd:PRK06176 365 EQDLLEDLEQAFAKI 379
|
|
| PRK06084 |
PRK06084 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
16-425 |
3.12e-69 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 180392 [Multi-domain] Cd Length: 425 Bit Score: 225.17 E-value: 3.12e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYvsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:PRK06084 1 MKLETLAIHAGYSPDPTTKAVAVPIYQTTSYAFDDTQHGADLFDL----------KVPGNIYTRIMNPTNDVLEQRVAAL 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAvGFADGVSETSVMAAAEEamakgRV 175
Cdd:PRK06084 71 EGGVGALAVASGMAAITYAIQTIAEAGDNIVSVAKLYGGTYNLLAHTLPRIGIET-RFAAHDDIAALEALIDE-----RT 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 176 SVILIETPANPTNSIVDIAMIGRVAevigkrqgHR---PIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAG 252
Cdd:PRK06084 145 KAVFCESIGNPAGNIIDIQALADAA--------HRhgvPLIV-DNTVATPVLCRPFEHGADIVVHSLTKYIGGHGTSIGG 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 253 -----------------AALGRKDVMK------------------QVKALRGaIGTQLDPHSCWMLGRSLETLQIRMERA 297
Cdd:PRK06084 216 ivvdsgkfpwaehkerfALLNTPDPSYhgvtyteafgpaafigrcRVVPLRN-MGAALSPFNAFLILQGLETLALRMERH 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 298 DSNARLVAEFLNAHPKVEKIHYLPFSD-PASAVGKVFAAqcSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTES 376
Cdd:PRK06084 295 TENALKVARYLQQHPQVAWVKYAGLPDhPEHELARRYMG--GKPASILSFGIKGGQAAGARFIDALKLVVRLVNIGDAKS 372
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 490580875 377 LASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLD 425
Cdd:PRK06084 373 LACHPASTTHRQLNDEELEKAGVSRDMVRLSIGIEHIDDIIADLAQALD 421
|
|
| PRK05994 |
PRK05994 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
19-427 |
2.06e-68 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 180344 [Multi-domain] Cd Length: 427 Bit Score: 223.05 E-value: 2.06e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsGRKEppegrgAGLVYSRFNHPNSEIVEDRLAVYERT 98
Cdd:PRK05994 9 ATLAVHAGAQPDPTTGARATPIYQTTSFVFNDADHAASLF----GLQA------FGNIYTRITNPTNAVLEERVAALEGG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 99 ESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVgFADGVSETSVMAAAEeamakGRVSVI 178
Cdd:PRK05994 79 TAALAVASGHAAQFLVFHTLLQPGDEFIAARKLYGGSINQFGHAFKSFGWQVR-WADADDPASFERAIT-----PRTKAI 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 179 LIETPANPTNSIVDIAMIGRVAevigKRQGhRPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAG------ 252
Cdd:PRK05994 153 FIESIANPGGTVTDIAAIAEVA----HRAG-LPLIV-DNTLASPYLIRPIEHGADIVVHSLTKFLGGHGNSMGGiivdgg 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 253 ----AALGRKDVMKQ------------------------VKALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARLV 304
Cdd:PRK05994 227 tfdwSKSGKYPMLSEprpeyhglvlhetfgnfafaiaarVLGLRD-LGPAISPFNAFLILTGIETLPLRMQRHSDNALAV 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 305 AEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPA 382
Cdd:PRK05994 306 AEWLKGHPKVSWVNYagLP-DDPYHALAQKYSPK--GAGAVFTFGLKGGYEAGVKLVSSLKLFSHLANIGDTRSLVIHPA 382
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 490580875 383 TMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:PRK05994 383 STTHRQLTDEQKVAAGAGPDVVRLSIGIEDVDDIIADLEQALAKA 427
|
|
| PRK07812 |
PRK07812 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
19-424 |
2.82e-68 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236105 Cd Length: 436 Bit Score: 223.09 E-value: 2.82e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsGRKEPpegrgaGLVYSRFNHPNSEIVEDRLAVYERT 98
Cdd:PRK07812 15 ETKQIHAGQTPDPATNARALPIYQTTSYTFDDTDHAAALF----GLAEP------GNIYTRIMNPTQDVVEQRIAALEGG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 99 ESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAEEAMAKgrvsVI 178
Cdd:PRK07812 85 VAALLLASGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYTLPKLGIE-VSFVEDPDDLDAWRAAVRPNTK----AF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 179 LIETPANPTNSIVDIAMIGRVAEVIGKrqghrPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL--G 256
Cdd:PRK07812 160 FAETISNPQIDVLDIPGVAEVAHEAGV-----PLIV-DNTIATPYLIRPLEHGADIVVHSATKYLGGHGTAIAGVIVdgG 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 RKD------------------------------VMKQVKALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAE 306
Cdd:PRK07812 234 TFDwtqgrfpgfttpdpsyhgvvfaelgppayaLKARVQLLRD-LGSAISPFNAFLIAQGLETLSLRIERHVANAQRVAE 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 307 FLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATM 384
Cdd:PRK07812 313 FLEARDEVASVNYagLP-SSPWYERAKRLAPK--GTGAVLSFELAGGVEAGKAFVNALTLHSHVANIGDVRSLVIHPAST 389
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 490580875 385 THSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSL 424
Cdd:PRK07812 390 THSQLTPEEQLATGVTPGLVRLAVGIEGIDDILADLEAGF 429
|
|
| PRK07582 |
PRK07582 |
cystathionine gamma-lyase; Validated |
68-425 |
3.98e-65 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 236061 Cd Length: 366 Bit Score: 212.93 E-value: 3.98e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 68 PEGRGAGL-VYSRFNHPNSEIVEDRLAVYERTEsCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNF 146
Cdd:PRK07582 35 SPGEPTGPdTYGRASNPTWRALEAALGELEGAE-ALVFPSGMAAITAVLRALLRPGDTVVVPADGYYQVRALAREYLAPL 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 147 GVSAV-----GFADGVSEtsvmaaaeeamakgRVSVILIETPANPTNSIVDIAMIGRVAevigKRQGhrPIIACDNTLLG 221
Cdd:PRK07582 114 GVTVReaptaGMAEAALA--------------GADLVLAETPSNPGLDVCDLAALAAAA----HAAG--ALLVVDNTTAT 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 222 PVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRK-DVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSN 300
Cdd:PRK07582 174 PLGQRPLELGADLVVASDTKALTGHSDLLLGYVAGRDpELMAAVERWRLLAGAIPGPFEAWLAHRSLGTLGLRFARQCAN 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 301 ARLVAEFLNAHPKVEKIHY--LPfSDPASAVGkvfAAQCSGAGSTFSFDiVGGQAASFKFLNALNIFKLAVSLGGtesla 378
Cdd:PRK07582 254 ALAVAELLAGHPAVRGVRYpgLP-GDPAHEVA---ARQMRRFGGLVSFE-LADAAAAERFVAASRLVVAATSFGG----- 323
|
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 490580875 379 shpatmTHSGvpADVRQRIG--VLDSTIRLSIGIEHPDDLIADLTLSLD 425
Cdd:PRK07582 324 ------VHTS--ADRRARWGdaVPEGFVRLSCGIEDTDDLVADLERALD 364
|
|
| PRK05968 |
PRK05968 |
hypothetical protein; Provisional |
34-420 |
5.34e-64 |
|
hypothetical protein; Provisional
Pssm-ID: 168320 [Multi-domain] Cd Length: 389 Bit Score: 210.71 E-value: 5.34e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 34 GAVKPPVFLTSTFVFKSAEDGRDFFdyvSGRKEPPegrgaglVYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAIST 113
Cdd:PRK05968 24 DAVVPPIFQTSLFTFDSYDEMEDVY---AGEKVRP-------IYSRGDNPTVRAFEEMLAKLEGAEDARGFASGMAAISS 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 114 TLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVsAVGFADGVSETSVMAAAEEamakgrVSVILIEtpaNPTNSIVDI 193
Cdd:PRK05968 94 TVLSFVEPGDRIVAVRHVYPDAFRLFETILKRMGV-EVDYVDGRDEEAVAKALPG------AKLLYLE---SPTSWVFEL 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 194 AMIGRVAEvIGKRQGHRPIIacDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKDVMKQVKALRGA-IG 272
Cdd:PRK05968 164 QDVAALAA-LAKRHGVVTMI--DNSWASPVFQRPITLGVDLVIHSASKYLGGHSDTVAGVVAGSKEHIARINAEAYPyLG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 273 TQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFSDPASavgkvfaAQCSGAGSTFSFdIVGGQ 352
Cdd:PRK05968 241 AKLSPFEAWLLLRGLRTLPLRMKAHEASALEIARRLKAHPVVERVCHPALANHPP-------AGLSGTSGLFSF-IFREG 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490580875 353 AASFKFLNALNIFKLAVSLGGTESLAshpatmthsgVPADVR----------QRIGVLDSTIRLSIGIEHPDDLIADL 420
Cdd:PRK05968 313 IDVRAFADALKLFRLGVSWGGHESLV----------VPAEVVlqqkaqpnsaARFGVSPRSVRLHVGLEGTEALWADL 380
|
|
| PRK05613 |
PRK05613 |
O-acetylhomoserine/O-acetylserine sulfhydrylase; |
19-427 |
6.89e-63 |
|
O-acetylhomoserine/O-acetylserine sulfhydrylase;
Pssm-ID: 168128 [Multi-domain] Cd Length: 437 Bit Score: 208.96 E-value: 6.89e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYvsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVYERT 98
Cdd:PRK05613 15 ETRSIHAGQSVDSDTSARNLPIYQTTSYVFDSAEHAKQRFAL----------EDLGPIYSRLTNPTVEALENRIASLEGG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 99 ESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAEEAMAKGrvsvI 178
Cdd:PRK05613 85 VHAVAFASGQAAETAAILNLAGAGDHIVTSPRLYGGTETLFLVTLNRLGIE-VTFVENPDDPESWQAAVQPNTKA----F 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 179 LIETPANPTNSIVDIAMIGRVAevigkrqgHR---PIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL 255
Cdd:PRK05613 160 FGETFANPQADVLDIPAVAEVA--------HRnqvPLIV-DNTIATAALVRPLELGADVVVASLTKFYTGNGSGLGGVLI 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 256 --GRKDVMKQ-------------------------------VKALRGAI---GTQLDPHSCWMLGRSLETLQIRMERADS 299
Cdd:PRK05613 231 dgGKFDWTVErdgkpvfpyfvtpdpayhglkyadlgapafgLKARAGLLrdtGATLSPFNAWVTAQGLDTLSLRLERHNE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 300 NARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQCSGagSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESL 377
Cdd:PRK05613 311 NAIKVAEFLNNHEKVAKVNFagLK-DSPWYATKEKLGLKYTG--SVLSFDIKGGKDEAWAFIDALKLHSNLANIGDVRSL 387
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 490580875 378 ASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:PRK05613 388 VVHPATTTHSQSDEAGLARAGITQATVRLSVGIEDIDDIIADLEGGFAAI 437
|
|
| PRK06434 |
PRK06434 |
cystathionine gamma-lyase; Validated |
28-426 |
9.43e-63 |
|
cystathionine gamma-lyase; Validated
Pssm-ID: 102374 [Multi-domain] Cd Length: 384 Bit Score: 207.06 E-value: 9.43e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 28 DPELseGAVKPPVFLTSTFVFKSAEDgRDFFDYVsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFSSG 107
Cdd:PRK06434 21 DPRF--GNVTTPIFETSTFVYPNSEK-EAYMDST---------RGMPYIYTRWGNPTVQAFEEKYAVLENAEHALSFSSG 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 108 MSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSavgfadgVSETSVMAAAEEAMAKGRVSVILIETPANPT 187
Cdd:PRK06434 89 MGAITSAILSLIKKGKRILSISDLYGQTFYFFNKVLKTLGIH-------VDYIDTDRLNSLDFDPSNYDLIYAESITNPT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 188 NSIVDIAMIGRVAevigkrqgHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAG-AALGRKDVMKQVKA 266
Cdd:PRK06434 162 LKVPDIKNVSSFC--------HENDVIVDATFASPYNQNPLDLGADVVIHSATKYISGHSDVVMGvAGTNNKSIFNNLVE 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 267 LRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlpfsdPASAVGKvfaAQCSGAGSTFSF 346
Cdd:PRK06434 234 RRKTLGSNPDPIQAYLALRGLKTLGLRMEKHNKNGMELARFLRDSKKISNVYY-----PDTEIGK---KVLRGFGGMLSF 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 347 DIVGGQAASfKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLDQ 426
Cdd:PRK06434 306 ELRSMEDVH-KFIRNLEIPMVAASLGGVESLITLPVETSHSSLSPEERERLGISDNLVRFSIGIEDIDDLIKDIENALSK 384
|
|
| PRK08134 |
PRK08134 |
O-acetylhomoserine aminocarboxypropyltransferase; Validated |
18-424 |
3.54e-61 |
|
O-acetylhomoserine aminocarboxypropyltransferase; Validated
Pssm-ID: 236159 Cd Length: 433 Bit Score: 204.59 E-value: 3.54e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 18 PETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFDYvsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PRK08134 9 FDTLALHAGAAPDPATGARAVPIHLTTSFVFRDSDHAAALFNL----------ERAGHVYSRISNPTVAVLEERVAALEG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAV----GFADGVSETsvmaaaeeamAKG 173
Cdd:PRK08134 79 GVGAIATASGQAALHLAIATLMGAGSHIVASSALYGGSHNLLHYTLRRFGIETTfvkpGDIDGWRAA----------IRP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 174 RVSVILIETPANPTNSIVDIAMIGRVAevigkRQGHRPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA 253
Cdd:PRK08134 149 NTRLLFGETLGNPGLEVLDIPTVAAIA-----HEAGVPLLV-DSTFTTPYLLRPFEHGADLVYHSATKFLGGHGTAIGGV 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 254 ----------ALGRKDVMKQ--------------------VKALRGAI---GTQLDPHSCWMLGRSLETLQIRMERADSN 300
Cdd:PRK08134 223 lvdggrfdweASGKFPELTEpyagfhgmvfaeestvaaflLRARREGLrdfGACLSPMNAWQLLQGIETLPLRMERHVAN 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 301 ARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLA 378
Cdd:PRK08134 303 TRKVVAFLASHPAVARVAHpeLE-SHPDHALAKRLLPR--GAGSVFSFDLKGGRAAGRKFIESLKLFSHLANVGDARSLV 379
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 490580875 379 SHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSL 424
Cdd:PRK08134 380 IHPASTTHFRMDAAALAAAGIGEGTIRLSIGLEDADDLIDDLKRAL 425
|
|
| PRK08248 |
PRK08248 |
homocysteine synthase; |
18-426 |
5.61e-61 |
|
homocysteine synthase;
Pssm-ID: 236201 [Multi-domain] Cd Length: 431 Bit Score: 203.92 E-value: 5.61e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 18 PETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRDFFdyvsGRKEPpegrgaGLVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PRK08248 9 LETLAIHAGQEIDPTTGSRAVPIYQTTSYGFRDSEHAANLF----SLKEF------GNIYTRIMNPTTDVFEKRIAALEG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADgvsetSVMAAAEEAMAKGRVSV 177
Cdd:PRK08248 79 GIGALAVSSGQAAITYSILNIASAGDEIVSSSSLYGGTYNLFAHTLPKLGIT-VKFVD-----PSDPENFEAAITDKTKA 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 178 ILIETPANPTNSIVDIAMIGRVAEvigkrQGHRPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL-- 255
Cdd:PRK08248 153 LFAETIGNPKGDVLDIEAVAAIAH-----EHGIPLIV-DNTFASPYLLRPIEHGADIVVHSATKFIGGHGTSIGGVIVds 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 256 GRKD--------------------------------VMKQVKALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARL 303
Cdd:PRK08248 227 GKFDwkgsgkfpgltepdpsyhglvytdavgeaayiTKARVQLLRD-LGAALSPFNSFLLLQGLETLHLRMERHSENALA 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 304 VAEFLNAHPKVEKIHY--LPfSDPASAVGKVFAAQcsGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHP 381
Cdd:PRK08248 306 VAKFLEEHEAVEWVSYpgLP-SHPSYELAKKYLPK--GQGAILTFGIKGGVEAGKKLIDSVKLFSHLANVGDSKSLIIHP 382
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 490580875 382 ATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSLDQ 426
Cdd:PRK08248 383 ASTTHQQLSEEEQLAAGVTPGLVRLSVGTEAIDDILDDLRQAIRQ 427
|
|
| PRK08861 |
PRK08861 |
O-succinylhomoserine (thiol)-lyase; |
18-421 |
1.21e-59 |
|
O-succinylhomoserine (thiol)-lyase;
Pssm-ID: 181567 [Multi-domain] Cd Length: 388 Bit Score: 199.35 E-value: 1.21e-59
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 18 PETQMLNYGYDPELSEGAVKPPVFLTSTFVFksaedgrdffdyvsgrkePPEGRGAGLVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PRK08861 6 PATIAVRTGIESDSQYHAVVPPIYLSTNYGF------------------PAFGEVPKYDYTRSGNPNRGLLEQTLSELES 67
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLaKTFHNFGVSAVGFADGVSETSVMAAAEEamakgRVSV 177
Cdd:PRK08861 68 GKGAVVTNCGTSALNLWVSALLGPDDLIVAPHDCYGGTYRLF-NTRANKGDFKVQFVDQSDAAALDAALAK-----KPKL 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 178 ILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR 257
Cdd:PRK08861 142 ILLETPSNPLVRVVDIAELCQKAKAVGA------LVAVDNTFLTPVLQKPLELGADFVIHSTTKYINGHSDVIGGVLITK 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 258 KDVMKQVKALRG-AIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIhYLPfSDPASAVGKVFAAQ 336
Cdd:PRK08861 216 TKEHAEELAWWGnCIGATGTPFDSYMTLRGIRTLGARMRVHEESAQQILAYLQTQSLVGTI-YHP-SLPEHPGHEIAKKQ 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 337 CSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGIEHPDDL 416
Cdd:PRK08861 294 QSGFGSMLSFEFAGSFEQLKVFVKALALFSLAESLGGVESLICHPASMTHRAMGEEALAEAGVSQQLLRLSVGLEDAQDL 373
|
....*
gi 490580875 417 IADLT 421
Cdd:PRK08861 374 IADLD 378
|
|
| PRK07269 |
PRK07269 |
cystathionine gamma-synthase; Reviewed |
16-425 |
1.01e-57 |
|
cystathionine gamma-synthase; Reviewed
Pssm-ID: 235983 Cd Length: 364 Bit Score: 193.50 E-value: 1.01e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 16 LHPETQMLNYGYDPELSEGAVKPPVFLTSTFvfksaedgrdffdyvsgrKEPPEGRGAGLVYSRFNHPNSEIVEDRLAVY 95
Cdd:PRK07269 5 LHINTILAQAGIKSDEATGALVTPLHFSTTY------------------QHPEFGQSTGFDYTRTKNPTRAKLEETLAAI 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 96 ERTESCALFSSGMSAIsTTLFAFVRPGDTVLHSQPLYGGTetllaktFHNFG-VSAVG---FADGVSETSVMAAAEEAma 171
Cdd:PRK07269 67 ESADYALATSSGMSAI-VLAFSVFPVGSKVVAVRDLYGGS-------FRWFNqQEKEGrfhFTYANTEEELIAAIEED-- 136
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 172 kgrVSVILIETPANPTNSIVDIAMIGRVAEVIGKRqghrpiIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIA 251
Cdd:PRK07269 137 ---TDIVYIETPTNPLMVEFDIEKVAKLAHAKGAK------VIVDNTFYSPIYQRPIELGADIVLHSATKYLSGHNDVLA 207
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 252 GAAL-GRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYlpfsdpasavg 330
Cdd:PRK07269 208 GVVVtNDLELYEKLFYNLNTTGAVLSPFDSYLLMRGLKTLSLRMERSTANAQEVVAFLKKSPAVKEVLY----------- 276
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 331 kvfaaqcSGAGSTFSFDIVGgQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGI 410
Cdd:PRK07269 277 -------TGKGGMISFKVAD-ETRIPHILNSLKVFTFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGI 348
|
410
....*....|....*
gi 490580875 411 EHPDDLIADLTLSLD 425
Cdd:PRK07269 349 EDARDLIADLKQALE 363
|
|
| PRK05939 |
PRK05939 |
cystathionine gamma-synthase family protein; |
34-425 |
1.02e-54 |
|
cystathionine gamma-synthase family protein;
Pssm-ID: 235650 [Multi-domain] Cd Length: 397 Bit Score: 186.43 E-value: 1.02e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 34 GAVKPPVFLTSTFVFKSAEDGRDFFdyvsgrkeppEGRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFSSGMSAIST 113
Cdd:PRK05939 8 GAVHKPIHTSVTYGYEDARDLIDVF----------QGKKPGFTYARQGTPTTAALEAKITKMEGGVGTVCFATGMAAIAA 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 114 TLFAFVRPGDTVLHSQPLYGGTETLLAkTFHNFGVSaVGFADGvseTSVMAAAEEAMAKGRVsvILIETPANPTNSIVDI 193
Cdd:PRK05939 78 VFLTLLRAGDHLVSSQFLFGNTNSLFG-TLRGLGVE-VTMVDA---TDVQNVAAAIRPNTRM--VFVETIANPGTQVADL 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 194 AMIGRVAEvigkRQGHRPIIacDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA-----------------ALG 256
Cdd:PRK05939 151 AGIGALCR----ERGLLYVV--DNTMTSPWLFRPKDVGASLVINSLSKYIAGHGNALGGAvtdtglfdwsaypnifpAYR 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 257 RKDV----MKQV--KALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASA 328
Cdd:PRK05939 225 KGDPqqwgLTQIrkKGLRD-MGATLSSEAAHRIAIGAETLALRVDRSCSNALALAQFLEAHPKVARVYYpgLA-SHPQHA 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 329 VGKvfaAQCSGAGSTFSFDIVGGqAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSI 408
Cdd:PRK05939 303 RAT---ELFRHYGGLLSFELADG-IDCFDFLNRLKLVIKATHLGDTRTLVIPVAPTIYYEMGAERRASMGIADSLIRVSV 378
|
410
....*....|....*..
gi 490580875 409 GIEHPDDLIADLTLSLD 425
Cdd:PRK05939 379 GIEDEADLIADFEQALD 395
|
|
| PRK07050 |
PRK07050 |
cystathionine beta-lyase; Provisional |
1-427 |
4.52e-49 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 180810 [Multi-domain] Cd Length: 394 Bit Score: 171.45 E-value: 4.52e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 1 MTAPHPSKtHIGNHALHPETQMLNyGYDpelsegAVKPPVFLTSTFVFKSAEDGRDFFDyvsgrkeppeGRGAGLVYSRF 80
Cdd:PRK07050 1 MTASTPKR-ALQTRIVQPDDQIPP-GFR------SFVTPVARASTVVFPDLATMRALDW----------RQDVQWRYGLH 62
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 81 NHPNSEIVEDRLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETL---LAKtfhNFGVSaVGFAD-- 155
Cdd:PRK07050 63 ATPTSLALAQRLAEIEGGRHALLQPSGLAAISLVYFGLVKAGDDVLIPDNAYGPNRDHgewLAR---DFGIT-VRFYDpl 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 156 ---GVSEtsvmaaaeeaMAKGRVSVILIETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGA 232
Cdd:PRK07050 139 igaGIAD----------LIQPNTRLIWLEAPGSVTMEVPDVPAITAAARARGV------VTAIDNTYSAGLAFKPFEHGV 202
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 233 DISLYSLTKYVGGHSDLIAGAALGRKD-VMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAH 311
Cdd:PRK07050 203 DISVQALTKYQSGGSDVLMGATITADAeLHAKLKLARMRLGIGVSADDCSLVLRGLPSLQVRLAAHDRSALEVAEWLKAR 282
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 312 PKVEKIHY--LPfSDPASAvgkVFAAQCSGAGSTFS--FDIVGGQAASFKFLNALNIFKLAVSLGGTESLAshpatmths 387
Cdd:PRK07050 283 PEIATVLHpaLP-DCPGHA---FWMRDFTGAGGLFSvvFDERYSPAQVDAFVEALELFAIGWSWGGACSLA--------- 349
|
410 420 430 440
....*....|....*....|....*....|....*....|....
gi 490580875 388 gVPADVRQ-RIGVLDST---IRLSIGIEHPDDLIADLTLSLDQV 427
Cdd:PRK07050 350 -MPYDVASmRTAKWPHRgtlVRLYIGLEDEADLIADLEQALEAA 392
|
|
| cysta_beta_ly_B |
TIGR01324 |
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate ... |
20-420 |
2.88e-46 |
|
cystathionine beta-lyase, bacterial; This model represents cystathionine beta-lyase (alternate name: beta-cystathionase), one of several pyridoxal-dependent enzymes of cysteine, methionine, and homocysteine metabolism. This enzyme is involved in the biosynthesis of Met from Cys. [Amino acid biosynthesis, Aspartate family]
Pssm-ID: 130391 [Multi-domain] Cd Length: 377 Bit Score: 163.51 E-value: 2.88e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 20 TQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRdffdyvsgrkeppeGRGAGLVYSRFNHPNSEIVEDRLAVYERTE 99
Cdd:TIGR01324 1 TRLIHSGRQPRFSQGSVNPPLQRASTVLFDSHAAQR--------------RAKGELTYGRRGTLTHFALQDAMCELEGGA 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 100 SCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVGFADGVSEtsvmaaAEEAMAKGRVSVIL 179
Cdd:TIGR01324 67 GCYLYPSGLAAVTNSILAFVKAGDHVLMVDSAYEPTRYFCDIVLKRMGVDITYYDPLIGE------DIATLIQPNTKVLF 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 180 IETPANPTNSIVDIAMIGRVAEVIGKrqghrpIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKD 259
Cdd:TIGR01324 141 LEAPSSITFEIQDIPAIAKAARNPGI------VIMIDNTWAAGLLFKPLEHGVDISIQAGTKYLVGHSDIMIGTVVANAR 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 260 VMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAvgkVFAAQC 337
Cdd:TIGR01324 215 TWDQLREHSYLMGQMVDADDAYTTLRGLRTLGVRLKQHQESSLAIAKWLSEQPEVARVLHpaLP-SCPGHE---FWKRDF 290
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 338 SGAGSTFSFDIVG-GQAASFKFLNALNIFKLAVSLGGTESLA--SHPATMTHSGVPADVRqrigvlDSTIRLSIGIEHPD 414
Cdd:TIGR01324 291 SGSSGLFSFVLQRlTQKQVHAFLDHLQLFGLGYSWGGYESLAlcNQPELGHRPNIKRNLE------GPLIRVHIGLENVD 364
|
....*.
gi 490580875 415 DLIADL 420
Cdd:TIGR01324 365 DLKADL 370
|
|
| PRK09028 |
PRK09028 |
cystathionine beta-lyase; Provisional |
19-420 |
8.15e-45 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181615 [Multi-domain] Cd Length: 394 Bit Score: 160.28 E-value: 8.15e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDGRdffdyvsgrkEPPEGRGAG-LVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PRK09028 6 ATKIVSAGRDKKWTKGVINPPVFRASTVVFDTVAEMR----------HAAKNRANGeMFYGRRGTPTHFAFQAAIVELEG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVGF----ADGVSEtsvmaaaeeaMAKG 173
Cdd:PRK09028 76 GAGTALYPSGAAAISNALLSFLKAGDHLLMVDSCYEPTRDLCDKILKGFGIETTYYdpmiGEGIRE----------LIRP 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 174 RVSVILIETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGA 253
Cdd:PRK09028 146 NTKVLFLESPGSITMEVQDVPTLSRIA------HEHDIVVMLDNTWASPINSRPFEMGVDISIQAATKYIVGHSDVMLGT 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 254 ALGRKDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHYLPFsdpASAVG-KV 332
Cdd:PRK09028 220 ATANEKHWDQLREHSYLMGQCTSPDDVYLAMRGLRTLGVRLAQHEKNALKVANWLATRPEVDHVRHPAF---ETCPGhEF 296
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 333 FAAQCSGAGSTFSFDI-VGGQAASFKFLNALNIFKLAVSLGGTESLashpaTMTHSGVpaDVRQRIGVLDST---IRLSI 408
Cdd:PRK09028 297 FKRDFSGSNGLFSFVLkQGDPKAVTALVEGMQHFKMGFSWGGFESL-----ILGVFGI--NKLRTATNWDFSkplIRLHI 369
|
410
....*....|..
gi 490580875 409 GIEHPDDLIADL 420
Cdd:PRK09028 370 GLEDVDDLIADL 381
|
|
| PRK05967 |
PRK05967 |
cystathionine beta-lyase; Provisional |
20-420 |
1.14e-43 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 235657 [Multi-domain] Cd Length: 395 Bit Score: 157.28 E-value: 1.14e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 20 TQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEdgrdffdyvsgrkePPEGRGAGLVYSRFNHPNSEIVEDRLAVYERTE 99
Cdd:PRK05967 15 TRLAHDGNDPGDYHGFVNPPVVHASTVLFPDAE--------------TMATRGQKYTYGTRGTPTTDALCKAIDALEGSA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 100 SCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSaVGFADGVSETSVMAAAeeamaKGRVSVIL 179
Cdd:PRK05967 81 GTILVPSGLAAVTVPFLGFLSPGDHALIVDSVYYPTRHFCDTMLKRLGVE-VEYYDPEIGAGIAKLM-----RPNTKVVH 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 180 IETPANPTNSIVDIAMIGRVAevigkrQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKD 259
Cdd:PRK05967 155 TEAPGSNTFEMQDIPAIAEAA------HRHGAIVMMDNTWATPLYFRPLDFGVDISIHAATKYPSGHSDILLGTVSANEK 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 260 VMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIHY--LPfSDPASAVGKvfaAQC 337
Cdd:PRK05967 229 CWPQLLEAHGTLGLCAGPDDTYQILRGLRTMGIRLEHHRKSALEIARWLEGRPDVARVLHpaLP-SFPGHEIWK---RDF 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 338 SGAGSTFSF----DIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPA----TMTHSGVPADVrqrigvldstIRLSIG 409
Cdd:PRK05967 305 SGASGIFSFvlaaGPEKGKAKAHAFLDALEIFGLGYSWGGYESLALHVKlgdrTVAKAPYAGPV----------IRLQIG 374
|
410
....*....|.
gi 490580875 410 IEHPDDLIADL 420
Cdd:PRK05967 375 LEDVPDLKADL 385
|
|
| PRK08114 |
PRK08114 |
cystathionine beta-lyase; Provisional |
19-421 |
4.00e-43 |
|
cystathionine beta-lyase; Provisional
Pssm-ID: 181231 [Multi-domain] Cd Length: 395 Bit Score: 155.63 E-value: 4.00e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 19 ETQMLNYGYDPELSEGAVKPPVFLTSTFVFKSAEDgrdffdyvsgRKEPPEGRGAG-LVYSRFNHPNSEIVEDRLAVYER 97
Cdd:PRK08114 7 DTQLVNAGRSKKYTQGSVNSVIQRASSLVFDSVEA----------KKHATRNRANGeLFYGRRGTLTHFSLQEAMCELEG 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 98 TESCALFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVGFADGVSEtsvmaaAEEAMAKGRVSV 177
Cdd:PRK08114 77 GAGCALYPCGAAAVANAILAFVEQGDHVLMTGTAYEPTQDFCSKILSKLGVTTTWFDPLIGA------DIAKLIQPNTKV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 178 ILIETPANPTNSIVDIAMIgrVAEVigKRQGHRPIIACDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGR 257
Cdd:PRK08114 151 VFLESPGSITMEVHDVPAI--VAAV--RSVNPDAVIMIDNTWAAGVLFKALDFGIDISIQAGTKYLVGHSDAMIGTAVAN 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 258 KDVMKQVKALRGAIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIhYLPfSDPASAVGKVFAAQC 337
Cdd:PRK08114 227 ARCWEQLRENSYLMGQMVDADTAYMTSRGLRTLGVRLRQHEESSLKVAEWLAEHPEVARV-NHP-ALPGCKGHEFWKRDF 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 338 SGAGSTFSFDIVG--GQAASFKFLNALNIFKLAVSLGGTESL--ASHPATMTHSGvPADVRQRIGVLdstIRLSIGIEHP 413
Cdd:PRK08114 305 TGSSGLFSFVLKKklTDEQLANYLDNFSLFSMAYSWGGFESLilANQPEEIAAIR-PAGEVDFTGTL---IRLHIGLEDV 380
|
....*...
gi 490580875 414 DDLIADLT 421
Cdd:PRK08114 381 DDLIADLA 388
|
|
| PLN02242 |
PLN02242 |
methionine gamma-lyase |
30-410 |
4.97e-37 |
|
methionine gamma-lyase
Pssm-ID: 215134 Cd Length: 418 Bit Score: 139.52 E-value: 4.97e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 30 ELSE-GAVKPPVFLTSTFVFKSAEDGRDFFdyvSGRKEPPEGRgagLVYSRFNHPNSEIVEDRLAVYERTESCALFSSGM 108
Cdd:PLN02242 28 EFGEhGGVNMSIEASATFTVMEPDTMRRMF---SGELGPDRDF---YIYSRHFNPTVLNLGRQMAALEGTEAAYCTASGM 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 109 SAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTF-HNFGVSAVgFADGVSETSVmaaaEEAMAKGRVSVILIETPANPT 187
Cdd:PLN02242 102 SAISSVLLQLCSSGGHVVASNTLYGGTHALLAHFLpRKCNITTT-FVDITDLEAV----KKAVVPGKTKVLYFESISNPT 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 188 NSIVDIAMIGRVAEVIGKRqghrpiIACDNTlLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAALGRKDVMKQVKAL 267
Cdd:PLN02242 177 LTVADIPELARIAHEKGVT------VVVDNT-FAPMVLSPARLGADVVVHSISKFISGGADIIAGAVCGPAELVNSMMDL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 268 R-GAI---GTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHPKveKIHYLPFSD-PASAVGKVFAAQCSGAGS 342
Cdd:PLN02242 250 HhGALmllGPTMNPKVAFELSERLPHLSLRMKEHCRRAMEYAKRMKELGL--KVIYPGLEDhPQHALLKSMANKGYGFGG 327
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490580875 343 TFSFDIVGGQAASfKFLNAL-NIFK---LAVSLGGTESLASHPATMTHSGVPADVRQRIGVLDSTIRLSIGI 410
Cdd:PLN02242 328 LLCLDMDTEERAN-RLMRYLqNSTQfgfMAVSLGYYETLMSCSGSSTSSELDPEEKAAAGISPGLVRMSVGY 398
|
|
| PRK06702 |
PRK06702 |
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase; |
26-424 |
3.65e-35 |
|
bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase;
Pssm-ID: 102505 [Multi-domain] Cd Length: 432 Bit Score: 134.80 E-value: 3.65e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 26 GYDPELSEGAVKPpVFLTSTFVFKSAEDGRDFFDYvsgrkeppegRGAGLVYSRFNHPNSEIVEDRLAVYERTESCALFS 105
Cdd:PRK06702 15 GYTPKNGEPRVLP-LYQSTTYKYDTSDDLAALFNL----------EAEGYIYTRIGNPTLAAFEQKLAELEGGVGAVATA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 106 SGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLLAKTFHNFGVSAVGFADGVSETSVMAAAeeamaKGRVSVILIETPAN 185
Cdd:PRK06702 84 SGQAAIMLAVLNICSSGDHLLCSSTVYGGTFNLFGVSLRKLGIDVTFFNPNLTADEIVALA-----NDKTKLVYAESLGN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 186 PTNSIVDIAMIGRVAevigkRQGHRPIIAcDNTLLGPVFQRPIEHGADISLYSLTKYVGGHSDLIAGAAL--GRKD---- 259
Cdd:PRK06702 159 PAMNVLNFKEFSDAA-----KELEVPFIV-DNTLATPYLCQAFEHGANIIVHSTTKYIDGHASSLGGIVIdgGNFDwtng 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 260 ---------------------------VMKQVKALRGaIGTQLDPHSCWMLGRSLETLQIRMERADSNARLVAEFLNAHP 312
Cdd:PRK06702 233 kypelvepdpsyhgvsyvqnfgaaayiVKARVQLLRD-YGNCMSPFNAYISNIGLETLHLRMERHSENALAVAKWLADHE 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 313 KVEKIHY--LPFSDPASAVGKVFAaqcSGAGSTFSFDIVGGQAASFKFLNALNIFKLAVSLGGTESLASHPATMTHSGVP 390
Cdd:PRK06702 312 RIEWVNYpgLDSNENYSLAQKYLK---KGASGVLTFGIKGGLEAAKEFIANVKLATLVTHVADARTCVIHPASTTHRQLS 388
|
410 420 430
....*....|....*....|....*....|....
gi 490580875 391 ADVRQRIGVLDSTIRLSIGIEHPDDLIADLTLSL 424
Cdd:PRK06702 389 AEDQRLAGVTSDLIRLSVGIEDVSDIIADLEAAL 422
|
|
| KBL_like |
cd06454 |
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate ... |
72-127 |
2.12e-03 |
|
KBL_like; this family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD corresponds to serine palmitoyltransferase (SPT), 5-aminolevulinate synthase (ALAS), 8-amino-7-oxononanoate synthase (AONS), and 2-amino-3-ketobutyrate CoA ligase (KBL). SPT is responsible for the condensation of L-serine with palmitoyl-CoA to produce 3-ketodihydrospingosine, the reaction of the first step in sphingolipid biosynthesis. ALAS is involved in heme biosynthesis; it catalyzes the synthesis of 5-aminolevulinic acid from glycine and succinyl-coenzyme A. AONS catalyses the decarboxylative condensation of l-alanine and pimeloyl-CoA in the first committed step of biotin biosynthesis. KBL catalyzes the second reaction step of the metabolic degradation pathway for threonine converting 2-amino-3-ketobutyrate, to glycine and acetyl-CoA. The members of this CD are widely found in all three forms of life.
Pssm-ID: 99747 [Multi-domain] Cd Length: 349 Bit Score: 39.85 E-value: 2.12e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 490580875 72 GAGLVYSRF---NHPNSEIVEDRLAVYERTESCALFSSGMSAISTTLFAFVRPGDTVLH 127
Cdd:cd06454 32 GVGAGGSRLisgTSDLHEELEEELAEFHGKEAALVFSSGYAANDGVLSTLAGKGDLIIS 90
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
103-318 |
8.76e-03 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 38.09 E-value: 8.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 103 LFSSGMSAISTTLFAFVRPGDTVLHSQPLYGGTETLlaktFHNFGVSAVGFADGVSETSVMAAAEEAMAKG-RVSVILIE 181
Cdd:cd00609 64 VTNGAQEALSLLLRALLNPGDEVLVPDPTYPGYEAA----ARLAGAEVVPVPLDEEGGFLLDLELLEAAKTpKTKLLYLN 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580875 182 TPANPTNSIVDIAMIGRVAEVIGKRQGhrpIIACDNTLLGPVFQRPIEHGAD--------ISLYSLTKYVGghsdlIAGA 253
Cdd:cd00609 140 NPNNPTGAVLSEEELEELAELAKKHGI---LIISDEAYAELVYDGEPPPALAlldayervIVLRSFSKTFG-----LPGL 211
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490580875 254 ALG-----RKDVMKQVKALRGAIGTQLDPHS----CWMLGRSLETLQIRMERADSNARLVAEFLNAHPKVEKIH 318
Cdd:cd00609 212 RIGyliapPEELLERLKKLLPYTTSGPSTLSqaaaAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVK 285
|
|
| |
