|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
2-527 |
0e+00 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 1002.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 2 NDYSQFAKLSPFELKDELIKLASTKKEKQMLNAGRGNPNFLATLPRRGFFRLGLFAVAESELSYSYMEqHLGGLPRIEGI 81
Cdd:PRK09275 1 EDEKKLEKLSPFELKDELIKLAKSKSARLMLNAGRGNPNWLATTPREAFFRLGQFAVEESRRSWSYPG-GLGGMPQKEGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 82 EARFERFVSDNRDQEGVVFLGRAISYVRDQLGLSASDFLHEMVEGILGCNYPVPPRMLRVSEQIVRQYLAKEMIGGQISP 161
Cdd:PRK09275 80 EERFEAFLEEHKDVPGIDFLRDAVSYVRDQLGFDADEFVYELVDGIIGDNYPVPDRMLKHTEKIVKDYLRQEMCGGRPPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 162 QDIDVFATEGGTAAMTYVFDTLQKNRLIKKSDKVAIGMPVFTPYIEIPQLDAYGLEEVSISADPEAGWQYPDSELEKLKD 241
Cdd:PRK09275 160 GEFDLFAVEGGTAAMCYIFDSLKENGLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADEENEWQYPDSELEKLRD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 242 PSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMILTDDVYGTFADDFKSLFSVCPKNTILVYSYSKYFGATGWR 321
Cdd:PRK09275 240 PSIKALFLVNPSNPPSVAMSDESLEKIADIVNEKRPDLMIITDDVYGTFVDDFRSLFAVLPYNTILVYSFSKYFGATGWR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 322 LGTIALRRDNVIDQAIRNLPEEDKASLDKRYSSIVTDVSALRFIDRLVADSRTVALNHTAGLSTPQQVQTVLFSLFALMD 401
Cdd:PRK09275 320 LGVIALHEDNVFDKLIAKLPEEKKKELDKRYSSLTTDPEKLKFIDRLVADSRQVALNHTAGLSTPQQVQMALFSLFALLD 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 402 ENDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVDYYTLLDLEKISRRLFGDEFAAWVRHEFSPNELLFRIADETGIVL 481
Cdd:PRK09275 400 EEDAYKKAMKDIIRRRYKALYEGLGLPEPEDPNNAAYYTLIDLEEWAEKNYGKEFADYLKKNYSPVDLLFRLAEETGVVL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 490580942 482 LPGRGFGTQHPSGRASLANLNEYEYAAIGRSLRKMADEYYAKFQQT 527
Cdd:PRK09275 480 LPGGGFGGPEWSVRVSLANLNEEDYAKIGKAIRKLLDEYYEEYKKS 525
|
|
| asp_4_decarbox |
TIGR03801 |
aspartate 4-decarboxylase; This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the ... |
10-524 |
0e+00 |
|
aspartate 4-decarboxylase; This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the side-chain carboxylate from L-aspartate, converting it to L-alanine plus carbon dioxide. It is a PLP-dependent enzyme, homologous to aspartate aminotransferase (EC 2.6.1.1). [Energy metabolism, Amino acids and amines]
Pssm-ID: 163513 Cd Length: 521 Bit Score: 904.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 10 LSPFELKDELIKLASTKKEKQ--MLNAGRGNPNFLATLPRRGFFRLGLFAVAESELSYSYMEqHLGGLPRIEGIEARFER 87
Cdd:TIGR03801 1 LSPFELKDELIKLAKSTKKSDrtMLNAGRGNPNWTATTPREAFFLLGQFAVEETRRSWSYPG-GLGGMPQKEGIEERFET 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 88 FVSDNRDQEGVVFLGRAISYVRDQLGLSASDFLHEMVEGILGCNYPVPPRMLRVSEQIVRQYLAKEMIGGQISPQDIDVF 167
Cdd:TIGR03801 80 FLAENKSQPGAEFLRDIISYVIDQLGFDPDAFLYEMCDGIIGDNYPVPDRMLPHSEKIVHQYLIQEMCGNKPPPGEFDLF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 168 ATEGGTAAMTYVFDTLQKNRLIKKSDKVAIGMPVFTPYIEIPQLDAYGLEEVSISADPE-----AGWQYPDSELEKLKDP 242
Cdd:TIGR03801 160 AVEGGTAAMCYIFDSLKANELLKKGDKIALMTPIFTPYLEIPELPRYDFEVVRIKADEMtedgtHTWQYPDKELEKLRDP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 243 SIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMILTDDVYGTFADDFKSLFSVCPKNTILVYSYSKYFGATGWRL 322
Cdd:TIGR03801 240 SIKALFVVNPSNPPSVAMSDESIEKIVDIVANDRPDLMILTDDVYGTFVDDFRSLFAELPYNTIGVYSFSKYFGATGWRL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 323 GTIALRRDNVIDQAIRNLPEEDKASLDKRYSSIVTDVSALRFIDRLVADSRTVALNHTAGLSTPQQVQTVLFSLFALMDE 402
Cdd:TIGR03801 320 GTIALHKDNIFDKLIAELPEEKKKELDKRYSSLTTEPRKLKFIDRLVADSRQVALNHTAGLSTPQQVQMALFSLFALMDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 403 NDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVDYYTLLDLEKISRRLFGDEFAAWVRHEFSPNELLFRIADETGIVLL 482
Cdd:TIGR03801 400 ENAYKAETKDICRRREKLLFRGLGLPLQEDPNDVAYYTLIDLEEWAEKNYGEEFSSYLKKNYSPVDVLFRLAEETGIVLL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 490580942 483 PGRGFGTQHPSGRASLANLNEYEYAAIGRSLRKMADEYYAKF 524
Cdd:TIGR03801 480 PGGGFGGPEWSVRVSLANLNEYDYAEIGRAIRKILDEYYEAW 521
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
131-511 |
1.22e-29 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 119.37 E-value: 1.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 131 NYPVPPRMLRVSEQIVRQYlaKEMIGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQ 210
Cdd:cd00609 31 GYYPDPGLPELREAIAEWL--GRRGGVDVPPEEI--VVTNGAQEALSLLLRAL-----LNPGDEVLVPDPTYPGYEAAAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 211 LdaYGLEEVSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTF 290
Cdd:cd00609 102 L--AGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAELAKKH--GILIISDEAYAEL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 291 ADD----FKSLFSVCPKNTILVYSYSKYFGATGWRLGTIALRRDNVIDQAIRNLPeedkasldkryssivtdvsalrfid 366
Cdd:cd00609 178 VYDgeppPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLP------------------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 367 rlvadsrtvalNHTAGLSTPQQVqtvlfSLFALMDENDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVD--YYTLLDL 444
Cdd:cd00609 233 -----------YTTSGPSTLSQA-----AAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVKPSggFFLWLDL 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490580942 445 EKISRRlfgdefaawvrhefspnELLFRIADETGIVLLPGRGFGTQHPSG-RASLANLNEYEYAAIGR 511
Cdd:cd00609 297 PEGDDE-----------------EFLERLLLEAGVVVRPGSAFGEGGEGFvRLSFATPEEELEEALER 347
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
139-520 |
1.03e-24 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 105.98 E-value: 1.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 139 LRvsEQIVRQYlaKEMIGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIeiPQLDAYGLEE 218
Cdd:COG0436 72 LR--EAIAAYY--KRRYGVDLDPDEI--LVTNGAKEALALALLAL-----LNPGDEVLVPDPGYPSYR--AAVRLAGGKP 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 219 VSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFA-DDFK-- 295
Cdd:COG0436 139 VPVPLDEENGFLPDPEALEAAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREH--DLLVISDEIYEELVyDGAEhv 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 296 SLFSV--CPKNTILVYSYSKYFGATGWRLGTIAlrrdnvidqairnLPEEdkasldkryssivtdvsalrFIDRLvadsR 373
Cdd:COG0436 217 SILSLpgLKDRTIVINSFSKSYAMTGWRIGYAV-------------GPPE--------------------LIAAL----L 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 374 TVALNHTAGLSTPQQVQTVlfslfALMDENDNYKKTLKRLIRRRQAALYA---ELGLDTPDDENSvdYYTLLDLEKISRR 450
Cdd:COG0436 260 KLQSNLTSCAPTPAQYAAA-----AALEGPQDYVEEMRAEYRRRRDLLVEglnEIGLSVVKPEGA--FYLFADVPELGLD 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490580942 451 lfGDEFAAWvrhefspneLLfriaDETGIVLLPGRGFGTQHPSG-RASLA----NLNEyeyaAIGRsLRKMADEY 520
Cdd:COG0436 333 --SEEFAER---------LL----EEAGVAVVPGSAFGPAGEGYvRISYAtseeRLEE----ALER-LARFLERY 387
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
171-508 |
7.13e-22 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 96.99 E-value: 7.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 171 GGTAAMTYVFDTLQKNrlikKSDKVAIGMPVFTPYIEIpqLDAYGLEEVSISADPEAGWQyPDSE-LEKLKDPSIKIFFC 249
Cdd:pfam00155 70 SGAGANIEALIFLLAN----PGDAILVPAPTYASYIRI--ARLAGGEVVRYPLYDSNDFH-LDFDaLEAALKEKPKVVLH 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 250 INPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVYGTFADDFKSLFSVCPK-----NTILVYSYSKYFGATGWRLGT 324
Cdd:pfam00155 143 TSPHNPTGTVATLEELEKLLDLAKEHN--ILLLVDEAYAGFVFGSPDAVATRALlaegpNLLVVGSFSKAFGLAGWRVGY 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 325 IAlrrdnvIDQAIrnlpeedkasldkryssivtdVSALRFIDRLVADSRTVALNHTAGLSTPQQVQtvlfslfalmdenD 404
Cdd:pfam00155 221 IL------GNAAV---------------------ISQLRKLARPFYSSTHLQAAAAAALSDPLLVA-------------S 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 405 NYKKTLKRLIRRRQ--AALYAELGLDTPDDENSVDYYTLLDLEKisrrlfGDEFAAwvrhefspnellfRIADETGIVLL 482
Cdd:pfam00155 261 ELEEMRQRIKERRDylRDGLQAAGLSVLPSQAGFFLLTGLDPET------AKELAQ-------------VLLEEVGVYVT 321
|
330 340
....*....|....*....|....*...
gi 490580942 483 PGRGFGTQhPSGRASLANLN--EYEYAA 508
Cdd:pfam00155 322 PGSSPGVP-GWLRITVAGGTeeELEELL 348
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09275 |
PRK09275 |
bifunctional aspartate transaminase/aspartate 4-decarboxylase; |
2-527 |
0e+00 |
|
bifunctional aspartate transaminase/aspartate 4-decarboxylase;
Pssm-ID: 236444 Cd Length: 527 Bit Score: 1002.46 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 2 NDYSQFAKLSPFELKDELIKLASTKKEKQMLNAGRGNPNFLATLPRRGFFRLGLFAVAESELSYSYMEqHLGGLPRIEGI 81
Cdd:PRK09275 1 EDEKKLEKLSPFELKDELIKLAKSKSARLMLNAGRGNPNWLATTPREAFFRLGQFAVEESRRSWSYPG-GLGGMPQKEGI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 82 EARFERFVSDNRDQEGVVFLGRAISYVRDQLGLSASDFLHEMVEGILGCNYPVPPRMLRVSEQIVRQYLAKEMIGGQISP 161
Cdd:PRK09275 80 EERFEAFLEEHKDVPGIDFLRDAVSYVRDQLGFDADEFVYELVDGIIGDNYPVPDRMLKHTEKIVKDYLRQEMCGGRPPK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 162 QDIDVFATEGGTAAMTYVFDTLQKNRLIKKSDKVAIGMPVFTPYIEIPQLDAYGLEEVSISADPEAGWQYPDSELEKLKD 241
Cdd:PRK09275 160 GEFDLFAVEGGTAAMCYIFDSLKENGLLKAGDKIALMTPIFTPYLEIPELPRYDLEVVHINADEENEWQYPDSELEKLRD 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 242 PSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMILTDDVYGTFADDFKSLFSVCPKNTILVYSYSKYFGATGWR 321
Cdd:PRK09275 240 PSIKALFLVNPSNPPSVAMSDESLEKIADIVNEKRPDLMIITDDVYGTFVDDFRSLFAVLPYNTILVYSFSKYFGATGWR 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 322 LGTIALRRDNVIDQAIRNLPEEDKASLDKRYSSIVTDVSALRFIDRLVADSRTVALNHTAGLSTPQQVQTVLFSLFALMD 401
Cdd:PRK09275 320 LGVIALHEDNVFDKLIAKLPEEKKKELDKRYSSLTTDPEKLKFIDRLVADSRQVALNHTAGLSTPQQVQMALFSLFALLD 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 402 ENDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVDYYTLLDLEKISRRLFGDEFAAWVRHEFSPNELLFRIADETGIVL 481
Cdd:PRK09275 400 EEDAYKKAMKDIIRRRYKALYEGLGLPEPEDPNNAAYYTLIDLEEWAEKNYGKEFADYLKKNYSPVDLLFRLAEETGVVL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|....*.
gi 490580942 482 LPGRGFGTQHPSGRASLANLNEYEYAAIGRSLRKMADEYYAKFQQT 527
Cdd:PRK09275 480 LPGGGFGGPEWSVRVSLANLNEEDYAKIGKAIRKLLDEYYEEYKKS 525
|
|
| asp_4_decarbox |
TIGR03801 |
aspartate 4-decarboxylase; This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the ... |
10-524 |
0e+00 |
|
aspartate 4-decarboxylase; This enzyme, aspartate 4-decarboxylase (EC 4.1.1.12), removes the side-chain carboxylate from L-aspartate, converting it to L-alanine plus carbon dioxide. It is a PLP-dependent enzyme, homologous to aspartate aminotransferase (EC 2.6.1.1). [Energy metabolism, Amino acids and amines]
Pssm-ID: 163513 Cd Length: 521 Bit Score: 904.37 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 10 LSPFELKDELIKLASTKKEKQ--MLNAGRGNPNFLATLPRRGFFRLGLFAVAESELSYSYMEqHLGGLPRIEGIEARFER 87
Cdd:TIGR03801 1 LSPFELKDELIKLAKSTKKSDrtMLNAGRGNPNWTATTPREAFFLLGQFAVEETRRSWSYPG-GLGGMPQKEGIEERFET 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 88 FVSDNRDQEGVVFLGRAISYVRDQLGLSASDFLHEMVEGILGCNYPVPPRMLRVSEQIVRQYLAKEMIGGQISPQDIDVF 167
Cdd:TIGR03801 80 FLAENKSQPGAEFLRDIISYVIDQLGFDPDAFLYEMCDGIIGDNYPVPDRMLPHSEKIVHQYLIQEMCGNKPPPGEFDLF 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 168 ATEGGTAAMTYVFDTLQKNRLIKKSDKVAIGMPVFTPYIEIPQLDAYGLEEVSISADPE-----AGWQYPDSELEKLKDP 242
Cdd:TIGR03801 160 AVEGGTAAMCYIFDSLKANELLKKGDKIALMTPIFTPYLEIPELPRYDFEVVRIKADEMtedgtHTWQYPDKELEKLRDP 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 243 SIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMILTDDVYGTFADDFKSLFSVCPKNTILVYSYSKYFGATGWRL 322
Cdd:TIGR03801 240 SIKALFVVNPSNPPSVAMSDESIEKIVDIVANDRPDLMILTDDVYGTFVDDFRSLFAELPYNTIGVYSFSKYFGATGWRL 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 323 GTIALRRDNVIDQAIRNLPEEDKASLDKRYSSIVTDVSALRFIDRLVADSRTVALNHTAGLSTPQQVQTVLFSLFALMDE 402
Cdd:TIGR03801 320 GTIALHKDNIFDKLIAELPEEKKKELDKRYSSLTTEPRKLKFIDRLVADSRQVALNHTAGLSTPQQVQMALFSLFALMDK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 403 NDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVDYYTLLDLEKISRRLFGDEFAAWVRHEFSPNELLFRIADETGIVLL 482
Cdd:TIGR03801 400 ENAYKAETKDICRRREKLLFRGLGLPLQEDPNDVAYYTLIDLEEWAEKNYGEEFSSYLKKNYSPVDVLFRLAEETGIVLL 479
|
490 500 510 520
....*....|....*....|....*....|....*....|..
gi 490580942 483 PGRGFGTQHPSGRASLANLNEYEYAAIGRSLRKMADEYYAKF 524
Cdd:TIGR03801 480 PGGGFGGPEWSVRVSLANLNEYDYAEIGRAIRKILDEYYEAW 521
|
|
| AAT_like |
cd00609 |
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent ... |
131-511 |
1.22e-29 |
|
Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the substrate in four kinds of reactions (1) transamination (movement of amino groups), (2) racemization (redistribution of enantiomers), (3) decarboxylation (removing COOH groups), and (4) various side-chain reactions depending on the enzyme involved. Pyridoxal phosphate (PLP) dependent enzymes were previously classified into alpha, beta and gamma classes, based on the chemical characteristics (carbon atom involved) of the reaction they catalyzed. The availability of several structures allowed a comprehensive analysis of the evolutionary classification of PLP dependent enzymes, and it was found that the functional classification did not always agree with the evolutionary history of these enzymes. The major groups in this CD corresponds to Aspartate aminotransferase a, b and c, Tyrosine, Alanine, Aromatic-amino-acid, Glutamine phenylpyruvate, 1-Aminocyclopropane-1-carboxylate synthase, Histidinol-phosphate, gene products of malY and cobC, Valine-pyruvate aminotransferase and Rhizopine catabolism regulatory protein.
Pssm-ID: 99734 [Multi-domain] Cd Length: 350 Bit Score: 119.37 E-value: 1.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 131 NYPVPPRMLRVSEQIVRQYlaKEMIGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQ 210
Cdd:cd00609 31 GYYPDPGLPELREAIAEWL--GRRGGVDVPPEEI--VVTNGAQEALSLLLRAL-----LNPGDEVLVPDPTYPGYEAAAR 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 211 LdaYGLEEVSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTF 290
Cdd:cd00609 102 L--AGAEVVPVPLDEEGGFLLDLELLEAAKTPKTKLLYLNNPNNPTGAVLSEEELEELAELAKKH--GILIISDEAYAEL 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 291 ADD----FKSLFSVCPKNTILVYSYSKYFGATGWRLGTIALRRDNVIDQAIRNLPeedkasldkryssivtdvsalrfid 366
Cdd:cd00609 178 VYDgeppPALALLDAYERVIVLRSFSKTFGLPGLRIGYLIAPPEELLERLKKLLP------------------------- 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 367 rlvadsrtvalNHTAGLSTPQQVqtvlfSLFALMDENDNYKKTLKRLIRRRQAALYAELGLDTPDDENSVD--YYTLLDL 444
Cdd:cd00609 233 -----------YTTSGPSTLSQA-----AAAAALDDGEEHLEELRERYRRRRDALLEALKELGPLVVVKPSggFFLWLDL 296
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490580942 445 EKISRRlfgdefaawvrhefspnELLFRIADETGIVLLPGRGFGTQHPSG-RASLANLNEYEYAAIGR 511
Cdd:cd00609 297 PEGDDE-----------------EFLERLLLEAGVVVRPGSAFGEGGEGFvRLSFATPEEELEEALER 347
|
|
| AspB |
COG0436 |
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; ... |
139-520 |
1.03e-24 |
|
Aspartate/methionine/tyrosine aminotransferase [Amino acid transport and metabolism]; Aspartate/methionine/tyrosine aminotransferase is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 440205 [Multi-domain] Cd Length: 387 Bit Score: 105.98 E-value: 1.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 139 LRvsEQIVRQYlaKEMIGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIeiPQLDAYGLEE 218
Cdd:COG0436 72 LR--EAIAAYY--KRRYGVDLDPDEI--LVTNGAKEALALALLAL-----LNPGDEVLVPDPGYPSYR--AAVRLAGGKP 138
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 219 VSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFA-DDFK-- 295
Cdd:COG0436 139 VPVPLDEENGFLPDPEALEAAITPRTKAIVLNSPNNPTGAVYSREELEALAELAREH--DLLVISDEIYEELVyDGAEhv 216
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 296 SLFSV--CPKNTILVYSYSKYFGATGWRLGTIAlrrdnvidqairnLPEEdkasldkryssivtdvsalrFIDRLvadsR 373
Cdd:COG0436 217 SILSLpgLKDRTIVINSFSKSYAMTGWRIGYAV-------------GPPE--------------------LIAAL----L 259
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 374 TVALNHTAGLSTPQQVQTVlfslfALMDENDNYKKTLKRLIRRRQAALYA---ELGLDTPDDENSvdYYTLLDLEKISRR 450
Cdd:COG0436 260 KLQSNLTSCAPTPAQYAAA-----AALEGPQDYVEEMRAEYRRRRDLLVEglnEIGLSVVKPEGA--FYLFADVPELGLD 332
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490580942 451 lfGDEFAAWvrhefspneLLfriaDETGIVLLPGRGFGTQHPSG-RASLA----NLNEyeyaAIGRsLRKMADEY 520
Cdd:COG0436 333 --SEEFAER---------LL----EEAGVAVVPGSAFGPAGEGYvRISYAtseeRLEE----ALER-LARFLERY 387
|
|
| Aminotran_1_2 |
pfam00155 |
Aminotransferase class I and II; |
171-508 |
7.13e-22 |
|
Aminotransferase class I and II;
Pssm-ID: 395103 [Multi-domain] Cd Length: 351 Bit Score: 96.99 E-value: 7.13e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 171 GGTAAMTYVFDTLQKNrlikKSDKVAIGMPVFTPYIEIpqLDAYGLEEVSISADPEAGWQyPDSE-LEKLKDPSIKIFFC 249
Cdd:pfam00155 70 SGAGANIEALIFLLAN----PGDAILVPAPTYASYIRI--ARLAGGEVVRYPLYDSNDFH-LDFDaLEAALKEKPKVVLH 142
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 250 INPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVYGTFADDFKSLFSVCPK-----NTILVYSYSKYFGATGWRLGT 324
Cdd:pfam00155 143 TSPHNPTGTVATLEELEKLLDLAKEHN--ILLLVDEAYAGFVFGSPDAVATRALlaegpNLLVVGSFSKAFGLAGWRVGY 220
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 325 IAlrrdnvIDQAIrnlpeedkasldkryssivtdVSALRFIDRLVADSRTVALNHTAGLSTPQQVQtvlfslfalmdenD 404
Cdd:pfam00155 221 IL------GNAAV---------------------ISQLRKLARPFYSSTHLQAAAAAALSDPLLVA-------------S 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 405 NYKKTLKRLIRRRQ--AALYAELGLDTPDDENSVDYYTLLDLEKisrrlfGDEFAAwvrhefspnellfRIADETGIVLL 482
Cdd:pfam00155 261 ELEEMRQRIKERRDylRDGLQAAGLSVLPSQAGFFLLTGLDPET------AKELAQ-------------VLLEEVGVYVT 321
|
330 340
....*....|....*....|....*...
gi 490580942 483 PGRGFGTQhPSGRASLANLN--EYEYAA 508
Cdd:pfam00155 322 PGSSPGVP-GWLRITVAGGTeeELEELL 348
|
|
| PRK08363 |
PRK08363 |
alanine aminotransferase; Validated |
129-488 |
1.91e-18 |
|
alanine aminotransferase; Validated
Pssm-ID: 181402 Cd Length: 398 Bit Score: 87.56 E-value: 1.91e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 129 GCNYPVPPR-MLRVSEQIVRQylAKEMIGGQISPQDIDVfaTEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIE 207
Cdd:PRK08363 62 GHNYYGPSEgLPELREAIVKR--EKRKNGVDITPDDVRV--TAAVTEALQLIFGAL-----LDPGDEILIPGPSYPPYTG 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 208 IpqLDAYGLEEVSISADPEAGWQyPD-SELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDV 286
Cdd:PRK08363 133 L--VKFYGGVPVEYRTIEEEGWQ-PDiDDIRKKITEKTKAIAVINPNNPTGALYEKKTLKEILDIAGEH--DLPVISDEI 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 287 YG--TFADDFKSLFSVCPK-NTILVYSYSKYFGATGWRLGTIALRRdnvidqairnlPEEdkasldkryssivtDVSALR 363
Cdd:PRK08363 208 YDlmTYEGKHVSPGSLTKDvPVIVMNGLSKVYFATGWRLGYIYFVD-----------PEG--------------KLAEVR 262
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 364 -FIDRLvADSRTVAlnhtaglSTPQQVqTVLFSLFALMDENDNYKKTLKRliRRRQaaLYAEL----GLDTPDDENSvdY 438
Cdd:PRK08363 263 eAIDKL-ARIRLCP-------NTPAQF-AAIAGLTGPMDYLEEYMKKLKE--RRDY--IYKRLneipGISTTKPQGA--F 327
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 490580942 439 YTlldLEKISRRLFGDEfaawvrhefspNELLFRIADETGIVLLPGRGFG 488
Cdd:PRK08363 328 YI---FPRIEEGPWKDD-----------KEFVLDVLHEAHVLFVHGSGFG 363
|
|
| PRK06348 |
PRK06348 |
pyridoxal phosphate-dependent aminotransferase; |
146-342 |
1.43e-17 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180537 Cd Length: 384 Bit Score: 84.39 E-value: 1.43e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 146 VRQYLAKEMiggQISPQDIDVFATEGGTAAMtyvFDTLQKnrLIKKSDKVAIGMPVFTPYIEipQLDAYGLEEVSISADP 225
Cdd:PRK06348 75 IIKYYSKNY---DLSFKRNEIMATVGACHGM---YLALQS--ILDPGDEVIIHEPYFTPYKD--QIEMVGGKPIILETYE 144
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 226 EAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYG--TFADDFKSL--FSVC 301
Cdd:PRK06348 145 EDGFQINVKKLEALITSKTKAIILNSPNNPTGAVFSKETLEEIAKIAIEY--DLFIISDEVYDgfSFYEDFVPMatLAGM 222
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 490580942 302 PKNTILVYSYSKYFGATGWRLGTIAlrRDNVIDQAIRNLPE 342
Cdd:PRK06348 223 PERTITFGSFSKDFAMTGWRIGYVI--APDYIIETAKIINE 261
|
|
| PRK07568 |
PRK07568 |
pyridoxal phosphate-dependent aminotransferase; |
143-338 |
2.88e-16 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181036 Cd Length: 397 Bit Score: 80.67 E-value: 2.88e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 143 EQIVRQYlakEMIGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIpqLDAYGLEEVSIS 222
Cdd:PRK07568 73 EAFAKYY---KKWGIDVEPDEI--LITNGGSEAILFAMMAI-----CDPGDEILVPEPFYANYNGF--ATSAGVKIVPVT 140
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 223 ADPEAGWQYPD-SELEKLKDPSIK-IFFCiNPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFADDFKSLFSV 300
Cdd:PRK07568 141 TKIEEGFHLPSkEEIEKLITPKTKaILIS-NPGNPTGVVYTKEELEMLAEIAKKH--DLFLISDEVYREFVYDGLKYTSA 217
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 490580942 301 C-----PKNTILVYSYSKYFGATGWRLGTIALRRDNVIDQAIR 338
Cdd:PRK07568 218 LsleglEDRVIIIDSVSKRYSACGARIGCLISKNKELIAAAMK 260
|
|
| PRK05764 |
PRK05764 |
aspartate aminotransferase; Provisional |
165-340 |
9.38e-14 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 235596 Cd Length: 393 Bit Score: 72.85 E-value: 9.38e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 165 DVFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQLdAYGlEEVSISADPEAGWQYPDSELEKLKDPSI 244
Cdd:PRK05764 93 QVIVTTGAKQALYNAFMAL-----LDPGDEVIIPAPYWVSYPEMVKL-AGG-VPVFVPTGEENGFKLTVEQLEAAITPKT 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 245 KIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYG--TFADD-FKSLFSVCP---KNTILVYSYSKYFGAT 318
Cdd:PRK05764 166 KALILNSPSNPTGAVYSPEELEAIADVAVEH--DIWVLSDEIYEklVYDGAeFTSIASLSPelrDRTITVNGFSKAYAMT 243
|
170 180
....*....|....*....|..
gi 490580942 319 GWRLGTIALRRDnVIdQAIRNL 340
Cdd:PRK05764 244 GWRLGYAAGPKE-LI-KAMSKL 263
|
|
| PRK08361 |
PRK08361 |
aspartate aminotransferase; Provisional |
143-338 |
3.82e-13 |
|
aspartate aminotransferase; Provisional
Pssm-ID: 236248 [Multi-domain] Cd Length: 391 Bit Score: 71.06 E-value: 3.82e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 143 EQIVRQYlaKEMIGGQISPQDIDVfaTEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQLDAYGLeeVSIS 222
Cdd:PRK08361 77 EAIAEYY--KKFYGVDVDVDNVIV--TAGAYEATYLAFESL-----LEEGDEVIIPDPAFVCYVEDAKIAEAKP--IRIP 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 223 ADPEAGWQY-PDSELEKLKDPSIKIffCIN-PSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFA-DDFK--SL 297
Cdd:PRK08361 146 LREENEFQPdPDELLELITKRTRMI--VINyPNNPTGATLDKEVAKAIADIAEDY--NIYILSDEPYEHFLyEGAKhyPM 221
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 490580942 298 FSVCPKNTILVYSYSKYFGATGWRLGtIALRRDNVIDQAIR 338
Cdd:PRK08361 222 IKYAPDNTILANSFSKTFAMTGWRLG-FVIAPEQVIKDMIK 261
|
|
| PRK06225 |
PRK06225 |
pyridoxal phosphate-dependent aminotransferase; |
123-335 |
7.76e-13 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235749 [Multi-domain] Cd Length: 380 Bit Score: 70.17 E-value: 7.76e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 123 MVEGILG---CNYPvPPRMLRVSEQIVRQYLAKEmiggqispqDIDVFATEGGTAAMTYVFDTLQKNrlikksdkvaiGM 199
Cdd:PRK06225 50 MIRCIEEgeyCKYP-PPEGFPELRELILKDLGLD---------DDEALITAGATESLYLVMRAFLSP-----------GD 108
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 200 PVFT--PYIEIPQL--DAYGLE--EVSISaDPEAGWQY-PDSELEKLkDPSIKIFFCINPSNPPSVKLDQRSLEKIADIV 272
Cdd:PRK06225 109 NAVTpdPGYLIIDNfaSRFGAEviEVPIY-SEECNYKLtPELVKENM-DENTRLIYLIDPLNPLGSSYTEEEIKEFAEIA 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490580942 273 DNHrpDLMILTDDVYGTFADDFKSLFSVCPKNTILVYSYSKYFGATGWRLGTIALRRDnVIDQ 335
Cdd:PRK06225 187 RDN--DAFLLHDCTYRDFAREHTLAAEYAPEHTVTSYSFSKIFGMAGLRIGAVVATPD-LIEV 246
|
|
| PRK07682 |
PRK07682 |
aminotransferase; |
188-326 |
8.76e-12 |
|
aminotransferase;
Pssm-ID: 181082 [Multi-domain] Cd Length: 378 Bit Score: 66.68 E-value: 8.76e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 188 LIKKSDKVAIGMPVFTPYIeiPQLDAYGLEEVSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEK 267
Cdd:PRK07682 101 IINPGDEVLIVEPSFVSYA--PLVTLAGGVPVPVATTLENEFKVQPAQIEAAITAKTKAILLCSPNNPTGAVLNKSELEE 178
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490580942 268 IADIVDNHrpDLMILTDDVYG--TFADDFKSLFSV--CPKNTILVYSYSKYFGATGWRLGTIA 326
Cdd:PRK07682 179 IAVIVEKH--DLIVLSDEIYAelTYDEAYTSFASIkgMRERTILISGFSKGFAMTGWRLGFIA 239
|
|
| tyr_nico_aTase |
TIGR01265 |
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal ... |
146-340 |
1.32e-11 |
|
tyrosine/nicotianamine family aminotransferase; This subfamily of pyridoxal phosphate-dependent enzymes includes known examples of both tyrosine aminotransferase from animals and nicotianamine aminotransferase from barley.
Pssm-ID: 188123 Cd Length: 403 Bit Score: 66.21 E-value: 1.32e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 146 VRQYLAKEMiGGQISPQDidVFATEGGTAAMTYVFDTLQKnrlikKSDKVAIGMPVFTPYIEIPQldAYGLEEVSISADP 225
Cdd:TIGR01265 82 VAEYLSSDL-PGKLTADD--VVLTSGCSQAIEICIEALAN-----PGANILVPRPGFPLYDTRAA--FSGLEVRLYDLLP 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 226 EAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVYGTFA---DDFKSLFSVCP 302
Cdd:TIGR01265 152 EKDWEIDLDGLESLADEKTVAIVVINPSNPCGSVFSRDHLQKIAEVAEKLG--IPIIADEIYGHMVfgdAPFIPMASFAS 229
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 490580942 303 KNTILVY-SYSKYFGATGWRLGTIAL--RRD---NVIDQAIRNL 340
Cdd:TIGR01265 230 IVPVLSLgGISKRWVVPGWRLGWIIIhdPHGifrDTVLQGLKNL 273
|
|
| PRK07309 |
PRK07309 |
pyridoxal phosphate-dependent aminotransferase; |
166-338 |
1.09e-08 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235985 Cd Length: 391 Bit Score: 57.04 E-value: 1.09e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 166 VFATEGGTAAMTYVFDtlqknrlikKSDKVAIGMPVFTPYIEIPQLDAYGLEEVSISAD-----PEAGWQYPDSELEKLK 240
Cdd:PRK07309 98 IGATEALSASLTAILE---------PGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENdfvltPEMLEKAILEQGDKLK 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 241 DpsikifFCIN-PSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYG--TFADDFK-SLFSVCPKNTILVYSYSKYFG 316
Cdd:PRK07309 169 A------VILNyPANPTGVTYSREQIKALADVLKKY--DIFVISDEVYSelTYTGEPHvSIAEYLPDQTILINGLSKSHA 240
|
170 180
....*....|....*....|..
gi 490580942 317 ATGWRLGTIALRRDnVIDQAIR 338
Cdd:PRK07309 241 MTGWRIGLIFAPAE-FTAQLIK 261
|
|
| PRK07324 |
PRK07324 |
transaminase; Validated |
166-335 |
1.13e-08 |
|
transaminase; Validated
Pssm-ID: 235989 Cd Length: 373 Bit Score: 57.25 E-value: 1.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 166 VFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQldAYGlEEVSI-SADPEAGWqYPD-SELEKLKDPS 243
Cdd:PRK07324 83 ILQTNGATGANFLVLYAL-----VEPGDHVISVYPTYQQLYDIPE--SLG-AEVDYwQLKEENGW-LPDlDELRRLVRPN 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 244 IKIFfCIN-PSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFADD--FKSLFSVCPKNtILVYSYSKYFGATGW 320
Cdd:PRK07324 154 TKLI-CINnANNPTGALMDRAYLEEIVEIARSV--DAYVLSDEVYRPLDEDgsTPSIADLYEKG-ISTNSMSKTYSLPGI 229
|
170
....*....|....*
gi 490580942 321 RLGTIALRRDnVIDQ 335
Cdd:PRK07324 230 RVGWIAANEE-VIDI 243
|
|
| tyr_amTase_E |
TIGR01264 |
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found ... |
165-325 |
1.75e-08 |
|
tyrosine aminotransferase, eukaryotic; This model describes tyrosine aminotransferase as found in animals and Trypanosoma cruzi. It is the first enzyme of a pathway of tyrosine degradation via homogentisate. Several plant enzyme designated as probable tyrosine aminotransferases are very closely related to an experimentally demonstrated nicotianamine aminotransferase, an enzyme in a siderophore (iron uptake chelator) biosynthesis pathway. These plant sequences are excluded from the model seed and score between the trusted an noise cutoffs. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273529 [Multi-domain] Cd Length: 401 Bit Score: 56.71 E-value: 1.75e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 165 DVFATEGGTAAMTYVFDTLQKnrlikKSDKVAIGMPVFTPYIEIPQldAYGLEEVSISADPEAGWQYPDSELEKLKDPSI 244
Cdd:TIGR01264 97 DVVLCSGCSHAIEMCIAALAN-----AGQNILVPRPGFPLYETLAE--SMGIEVKLYNLLPDKSWEIDLKQLESLIDEKT 169
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 245 KIFFCINPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVYGTFA---DDFKSLFSVCPKNTILVY-SYSKYFGATGW 320
Cdd:TIGR01264 170 AALIVNNPSNPCGSVFSRQHLEEILAVAERQC--LPIIADEIYGDMVfsgATFEPLASLSSTVPILSCgGLAKRWLVPGW 247
|
....*
gi 490580942 321 RLGTI 325
Cdd:TIGR01264 248 RLGWI 252
|
|
| PTZ00433 |
PTZ00433 |
tyrosine aminotransferase; Provisional |
193-332 |
2.70e-08 |
|
tyrosine aminotransferase; Provisional
Pssm-ID: 185613 Cd Length: 412 Bit Score: 55.95 E-value: 2.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 193 DKVAIGMPVFTPYIEIpqLDAYGLEEVSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIV 272
Cdd:PTZ00433 129 DNILVPAPGFPHYETV--CKAYGIEMRFYNCRPEKDWEADLDEIRRLVDDRTKALIMTNPSNPCGSNFSRKHVEDIIRLC 206
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 273 DNHRpdLMILTDDVY-------GTFAD--DFKSlfsvcPKNTILVYSYSKYFGATGWRLG-TIALRRDNV 332
Cdd:PTZ00433 207 EELR--LPLISDEIYagmvfngATFTSvaDFDT-----TVPRVILGGTAKNLVVPGWRLGwLLLVDPHGN 269
|
|
| PTZ00377 |
PTZ00377 |
alanine aminotransferase; Provisional |
165-287 |
7.84e-08 |
|
alanine aminotransferase; Provisional
Pssm-ID: 240391 [Multi-domain] Cd Length: 481 Bit Score: 54.97 E-value: 7.84e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 165 DVFATEGGTAAMTYVFDTLQKNrlikKSDKVAIGMPVFTPYIEipQLDAYGLEEVSISADPEAGWQYPDSELE------K 238
Cdd:PTZ00377 140 DIFLTDGASSGIKLLLQLLIGD----PSDGVMIPIPQYPLYSA--AITLLGGKQVPYYLDEEKGWSLDQEELEeayeqaV 213
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 490580942 239 LKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVY 287
Cdd:PTZ00377 214 RNGITPRALVVINPGNPTGQVLTRDVMEEIIKFCYEKG--IVLMADEVY 260
|
|
| PRK06107 |
PRK06107 |
aspartate transaminase; |
252-340 |
1.52e-07 |
|
aspartate transaminase;
Pssm-ID: 180403 Cd Length: 402 Bit Score: 53.59 E-value: 1.52e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 252 PSNPPSVKLDQRSLEKIADIVDNHrPDLMILTDDVYGT--FAD-DFKSLFSVCP--KNTILVYS-YSKYFGATGWRLGTI 325
Cdd:PRK06107 175 PSNPTGAVYSRAELRALADVLLRH-PHVLVLTDDIYDHirFDDePTPHLLAAAPelRDRVLVTNgVSKTYAMTGWRIGYA 253
|
90
....*....|....*
gi 490580942 326 ALRRDNVidQAIRNL 340
Cdd:PRK06107 254 AGPADLI--AAINKL 266
|
|
| PRK06855 |
PRK06855 |
pyridoxal phosphate-dependent aminotransferase; |
147-287 |
5.34e-07 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180734 Cd Length: 433 Bit Score: 51.87 E-value: 5.34e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 147 RQYLAKEMI---GGQISPQDIDVFatEGGTAAMTYVFDTLQKN-RLIKKSdkvaigmPVFTPYIEIPQLDAyGLEEVSIS 222
Cdd:PRK06855 79 REFLAELNNkrgGAQITPDDIIFF--NGLGDAIAKIYGLLRREaRVIGPS-------PAYSTHSSAEAAHA-GYPPVTYR 148
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 490580942 223 ADPEAGWqYPD-SELE-KLK-DPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDnhRPDLMILTDDVY 287
Cdd:PRK06855 149 LDPENNW-YPDlDDLEnKVKyNPSIAGILLINPDNPTGAVYPKEILREIVDIAR--EYDLFIICDEIY 213
|
|
| PLN00143 |
PLN00143 |
tyrosine/nicotianamine aminotransferase; Provisional |
142-334 |
1.15e-06 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 165711 [Multi-domain] Cd Length: 409 Bit Score: 50.78 E-value: 1.15e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 142 SEQIVRQYLAKEMiGGQISPQDidVFATEGGTAAMTYVFDTLQK---NRLIKKSdkvaiGMPVFTPY-----IEIPQLDA 213
Cdd:PLN00143 79 ARRAIADYLSNDL-PYQLSPDD--VYLTLGCKHAAEIIIKVLARpeaNILLPRP-----GFPDVETYaifhhLEIRHFDL 150
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 214 YgleevsisadPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVdnHRPDLMILTDDVYGTFADD 293
Cdd:PLN00143 151 L----------PEKGWEVDLDAVEAIADENTIAMVIINPGNPCGSVYSYEHLNKIAETA--RKLGILVIADEVYGHIVFG 218
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 490580942 294 FK-----SLF-SVCPknTILVYSYSKYFGATGWRLGTIA-------LRRDNVID 334
Cdd:PLN00143 219 SKpfvpmGLFaSIVP--VITLGSISKRWMIPGWGLGWLVtcdpsglLQICEIAD 270
|
|
| PLN02656 |
PLN02656 |
tyrosine transaminase |
165-323 |
1.21e-06 |
|
tyrosine transaminase
Pssm-ID: 178262 [Multi-domain] Cd Length: 409 Bit Score: 50.69 E-value: 1.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 165 DVFATEGGTAAMTYVFDTLQKNRLikksdKVAIGMPVFTPYieipQLDA--YGLEEVSISADPEAGWQYPDSELEKLKDP 242
Cdd:PLN02656 98 DVFITSGCTQAIDVALSMLARPGA-----NILLPRPGFPIY----ELCAafRHLEVRYVDLLPEKGWEVDLDAVEALADQ 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 243 SIKIFFCINPSNPPSVKLDQRSLEKIADIVDnhRPDLMILTDDVYGTFADDFKSLF------SVCPKNTIlvYSYSKYFG 316
Cdd:PLN02656 169 NTVALVIINPGNPCGNVYSYQHLKKIAETAE--KLKILVIADEVYGHLAFGSNPFVpmgvfgSIVPVLTL--GSLSKRWI 244
|
....*..
gi 490580942 317 ATGWRLG 323
Cdd:PLN02656 245 VPGWRLG 251
|
|
| PRK07683 |
PRK07683 |
aminotransferase A; Validated |
163-323 |
1.58e-06 |
|
aminotransferase A; Validated
Pssm-ID: 236075 Cd Length: 387 Bit Score: 50.49 E-value: 1.58e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 163 DIDVFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVFTPYIEIPQLdaYGLEEVSISADPeAGWQYPDSELEKLKDP 242
Cdd:PRK07683 89 ESEIIVTIGASEAIDIAFRTI-----LEPGTEVILPAPIYPGYEPIIRL--CGAKPVFIDTRS-TGFRLTAEALENAITE 160
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 243 SIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYG--TFADDFKSL--FSVCPKNTILVYSYSKYFGAT 318
Cdd:PRK07683 161 KTRCVVLPYPSNPTGVTLSKEELQDIADVLKDK--NIFVLSDEIYSelVYEQPHTSIahFPEMREKTIVINGLSKSHSMT 238
|
....*
gi 490580942 319 GWRLG 323
Cdd:PRK07683 239 GWRIG 243
|
|
| PRK08960 |
PRK08960 |
pyridoxal phosphate-dependent aminotransferase; |
219-323 |
7.20e-06 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 181595 Cd Length: 387 Bit Score: 48.51 E-value: 7.20e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 219 VSISADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMIltDDVYG--TFADDFKS 296
Cdd:PRK08960 141 QLVPVGPDSRYQLTPALVERHWNADTVGALVASPANPTGTLLSRDELAALSQALRARGGHLVV--DEIYHglTYGVDAAS 218
|
90 100
....*....|....*....|....*..
gi 490580942 297 LFSVcPKNTILVYSYSKYFGATGWRLG 323
Cdd:PRK08960 219 VLEV-DDDAFVLNSFSKYFGMTGWRLG 244
|
|
| PLN02187 |
PLN02187 |
rooty/superroot1 |
158-327 |
1.31e-05 |
|
rooty/superroot1
Pssm-ID: 215119 [Multi-domain] Cd Length: 462 Bit Score: 47.80 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 158 QISPQDIdvFATEGGTAAMTYVFDTLQKNRlikksdkvaigMPVFTPYIEIPQLDAY----GLEEVSISADPEAGWQYPD 233
Cdd:PLN02187 128 KLTPEDI--FLTAGCNQGIEIVFESLARPN-----------ANILLPRPGFPHYDARaaysGLEVRKFDLLPEKEWEIDL 194
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 234 SELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVdnHRPDLMILTDDVYG--TFADD-FKSL---FSVCPknTIL 307
Cdd:PLN02187 195 EGIEAIADENTVAMVVINPNNPCGNVYSHDHLKKVAETA--RKLGIMVISDEVYDrtIFGDNpFVSMgkfASIVP--VLT 270
|
170 180
....*....|....*....|
gi 490580942 308 VYSYSKYFGATGWRLGTIAL 327
Cdd:PLN02187 271 LAGISKGWVVPGWKIGWIAL 290
|
|
| PRK06108 |
PRK06108 |
pyridoxal phosphate-dependent aminotransferase; |
193-490 |
1.95e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180404 Cd Length: 382 Bit Score: 46.86 E-value: 1.95e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 193 DKVAIGMPVFTPYIEIPQLdaYGLEEVSISADPEA-GWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADI 271
Cdd:PRK06108 109 DEVVAVTPLWPNLVAAPKI--LGARVVCVPLDFGGgGWTLDLDRLLAAITPRTRALFINSPNNPTGWTASRDDLRAILAH 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 272 VDNHrpDLMILTDDVYGTF-------ADDFKSLFSvcPKNTIL-VYSYSKYFGATGWRLGTIALRRDnvIDQAIRNLPEe 343
Cdd:PRK06108 187 CRRH--GLWIVADEVYERLyyapggrAPSFLDIAE--PDDRIIfVNSFSKNWAMTGWRLGWLVAPPA--LGQVLEKLIE- 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 344 dkasldkrYS-SIVTD------VSALR----FIDRLVADSRTV------ALNHTAGLSTPQQvqtvlfslfalmdendny 406
Cdd:PRK06108 260 --------YNtSCVAQfvqraaVAALDegedFVAELVARLRRSrdhlvdALRALPGVEVAKP------------------ 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 407 kktlkrlirrrQAALYAELGLDTPDDensvdyytlldlekiSRRlfgdefaawvrhefspneLLFRIADETGIVLLPGRG 486
Cdd:PRK06108 314 -----------DGAMYAFFRIPGVTD---------------SLA------------------LAKRLVDEAGLGLAPGTA 349
|
....
gi 490580942 487 FGTQ 490
Cdd:PRK06108 350 FGPG 353
|
|
| PLN02607 |
PLN02607 |
1-aminocyclopropane-1-carboxylate synthase |
251-338 |
3.98e-05 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 215327 [Multi-domain] Cd Length: 447 Bit Score: 46.04 E-value: 3.98e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 251 NPSNPPSVKLDQRSLEKIADIVDnhRPDLMILTDDVYG--TF-ADDFKSLFSV--------CPKNTILVYSYSKYFGATG 319
Cdd:PLN02607 208 NPSNPLGATVQRSVLEDILDFVV--RKNIHLVSDEIYSgsVFsASEFVSVAEIveargykgVAERVHIVYSLSKDLGLPG 285
|
90
....*....|....*....
gi 490580942 320 WRLGTIALRRDNVIDQAIR 338
Cdd:PLN02607 286 FRVGTIYSYNDKVVTTARR 304
|
|
| PRK13355 |
PRK13355 |
bifunctional HTH-domain containing protein/aminotransferase; Provisional |
224-323 |
6.49e-05 |
|
bifunctional HTH-domain containing protein/aminotransferase; Provisional
Pssm-ID: 237361 [Multi-domain] Cd Length: 517 Bit Score: 45.50 E-value: 6.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 224 DPEAGWqYPDSELEKLK-DPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYGTFADDFK---SLFS 299
Cdd:PRK13355 262 DEQSEW-YPDIDDIRSKiTSRTKAIVIINPNNPTGALYPREVLQQIVDIAREH--QLIIFSDEIYDRLVMDGLehtSIAS 338
|
90 100
....*....|....*....|....*
gi 490580942 300 VCPKNTILVYS-YSKYFGATGWRLG 323
Cdd:PRK13355 339 LAPDLFCVTFSgLSKSHMIAGYRIG 363
|
|
| PLN00145 |
PLN00145 |
tyrosine/nicotianamine aminotransferase; Provisional |
146-339 |
7.83e-05 |
|
tyrosine/nicotianamine aminotransferase; Provisional
Pssm-ID: 215074 [Multi-domain] Cd Length: 430 Bit Score: 45.15 E-value: 7.83e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 146 VRQYLAKEMiGGQISPQDIdvFATEGGTAAMTYVFDTLQKNrlikksdkvaiGMPVFTPYIEIPQLDA----YGLEEVSI 221
Cdd:PLN00145 103 IAEYLSRDL-PYELSTDDI--YLTAGCAQAIEIIMSVLAQP-----------GANILLPRPGYPLYEAravfSGLEVRHF 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 222 SADPEAGWQYPDSELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVdnHRPDLMILTDDVYGTFAddFKS----- 296
Cdd:PLN00145 169 DLLPERGWEVDLEGVEALADENTVAMVIINPNNPCGSVYSYEHLAKIAETA--RKLGILVIADEVYDHLT--FGSkpfvp 244
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 490580942 297 --LF-SVCPKNTIlvYSYSKYFGATGWRLGTIA-------LRRDNVIDqAIRN 339
Cdd:PLN00145 245 mgVFgEVAPVLTL--GSISKRWVVPGWRLGWIAtcdpngiLKETKVVD-SIRN 294
|
|
| PRK06836 |
PRK06836 |
pyridoxal phosphate-dependent aminotransferase; |
146-327 |
8.76e-05 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180720 Cd Length: 394 Bit Score: 44.80 E-value: 8.76e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 146 VRQYLAKEM---IGGQISPQDIdvFATEGGTAAMTYVFDTLqknrlIKKSDKVAIGMPVF---TPYIeipqlDAYGLEEV 219
Cdd:PRK06836 78 VREAIAESLnrrFGTPLTADHI--VMTCGAAGALNVALKAI-----LNPGDEVIVFAPYFveyRFYV-----DNHGGKLV 145
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 220 SISADPEAgWQyPD-SELEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDN----HRPDLMILTDDVYGTFA-DD 293
Cdd:PRK06836 146 VVPTDTDT-FQ-PDlDALEAAITPKTKAVIINSPNNPTGVVYSEETLKALAALLEEkskeYGRPIYLISDEPYREIVyDG 223
|
170 180 190
....*....|....*....|....*....|....*.
gi 490580942 294 FK--SLFSVCpKNTILVYSYSKYFGATGWRLGTIAL 327
Cdd:PRK06836 224 AEvpYIFKYY-DNSIVVYSFSKSLSLPGERIGYIAV 258
|
|
| PRK07550 |
PRK07550 |
aminotransferase; |
211-518 |
1.33e-04 |
|
aminotransferase;
Pssm-ID: 181026 [Multi-domain] Cd Length: 386 Bit Score: 44.18 E-value: 1.33e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 211 LDAYGLEEVSISADPEAGWqYPDSE-LEKLKDPSIKIFFCINPSNPPSVKLDQRSLEKIADIVDNHRPDLMIltDDVYGT 289
Cdd:PRK07550 131 LDMLGIRPVYLPCDEGPGL-LPDPAaAEALITPRTRAIALVTPNNPTGVVYPPELLHELYDLARRHGIALIL--DETYRD 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 290 FADDF---KSLFSV--CPKNTILVYSYSKYFGATGWRLGTIAlrrdnvidqairnlpeedkASlDKRYSSIvtdvsaLRF 364
Cdd:PRK07550 208 FDSGGgapHDLFADpdWDDTLVHLYSFSKSYALTGHRVGAVV-------------------AS-PARIAEI------EKF 261
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 365 IDrlvadsrTVALnhtaglSTPQQVQ-TVLFSLFALMD---ENdnykktlKRLIRRRQAALYAELgldtpddeNSVDYYT 440
Cdd:PRK07550 262 MD-------TVAI------CAPRIGQiAVAWGLPNLADwraGN-------RAEIARRRDAFRAVF--------ARLPGWE 313
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 441 LLDLekisrrlfGDEFAaWVRHEF---SPNELLFRIADETGIVLLPGRGFGT-QHPSGRASLANLNEYEYAAIGRSLRKM 516
Cdd:PRK07550 314 LLAS--------GAYFA-YVRHPFpdrPSREVARRLAKEAGILCLPGTMFGPgQEGYLRLAFANADVAGIGELVERLRAF 384
|
..
gi 490580942 517 AD 518
Cdd:PRK07550 385 AP 386
|
|
| PLN02376 |
PLN02376 |
1-aminocyclopropane-1-carboxylate synthase |
227-419 |
1.87e-04 |
|
1-aminocyclopropane-1-carboxylate synthase
Pssm-ID: 178004 [Multi-domain] Cd Length: 496 Bit Score: 43.92 E-value: 1.87e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 227 AGWQYPDSELEKLKdpsIKIFFCINPSNPPSVKLDQRSLEKIADIVDnhRPDLMILTDDVYGT--FAD-DFKSLFSVCPK 303
Cdd:PLN02376 186 ADWAYKKAQESNKK---VKGLILTNPSNPLGTMLDKDTLTNLVRFVT--RKNIHLVVDEIYAAtvFAGgDFVSVAEVVND 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 304 NTI---------LVYSYSKYFGATGWRLGTIALRRDNVIDQAiRNLPEEDKASLDKRYsSIVTDVSALRFIDR-LVADSR 373
Cdd:PLN02376 261 VDIsevnvdlihIVYSLSKDMGLPGFRVGIVYSFNDSVVSCA-RKMSSFGLVSSQTQL-MLASMLSDDQFVDNfLMESSR 338
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 490580942 374 TVALNHTAGLSTPQQVQTVLFS----LFALMDendnykktLKRLIRRRQA 419
Cdd:PLN02376 339 RLGIRHKVFTTGIKKADIACLTsnagLFAWMD--------LRHLLRDRNS 380
|
|
| RfaE_like |
cd01172 |
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the ... |
255-343 |
5.86e-04 |
|
RfaE encodes a bifunctional ADP-heptose synthase involved in the biosynthesis of the lipopolysaccharide (LPS) core precursor ADP-L-glycero-D-manno-heptose. LPS plays an important role in maintaining the structural integrity of the bacterial outer membrane of gram-negative bacteria. RfaE consists of two domains, a sugar kinase domain, represented here, and a domain belonging to the cytidylyltransferase superfamily.
Pssm-ID: 238577 [Multi-domain] Cd Length: 304 Bit Score: 42.16 E-value: 5.86e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 255 PPSVKLDQRSLEKIADIVDnhRPDLMILTDDVYGTFADDF-KSLFSVCPKNTILVY------SYSKYFGATGW------- 320
Cdd:cd01172 115 PLSAEEEQRLIERIAERLP--EADVVILSDYGKGVLTPRViEALIAAARELGIPVLvdpkgrDYSKYRGATLLtpnekea 192
|
90 100
....*....|....*....|....
gi 490580942 321 RLGT-IALRRDNVIDQAIRNLPEE 343
Cdd:cd01172 193 REALgDEINDDDELEAAGEKLLEL 216
|
|
| PRK07337 |
PRK07337 |
pyridoxal phosphate-dependent aminotransferase; |
252-323 |
1.02e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 180937 Cd Length: 388 Bit Score: 41.58 E-value: 1.02e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490580942 252 PSNPPSVKLDQRSLEKIADIVDNhRPDLMILtDDVY-GTFADDF-KSLFSVCPkNTILVYSYSKYFGATGWRLG 323
Cdd:PRK07337 172 PSNPTGTSIAPDELRRIVEAVRA-RGGFTIV-DEIYqGLSYDAApVSALSLGD-DVITINSFSKYFNMTGWRLG 242
|
|
| PRK05957 |
PRK05957 |
pyridoxal phosphate-dependent aminotransferase; |
250-323 |
1.05e-03 |
|
pyridoxal phosphate-dependent aminotransferase;
Pssm-ID: 235654 Cd Length: 389 Bit Score: 41.60 E-value: 1.05e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 250 INPSNPPSVKLDQRSLEKIADIVDNHRpdLMILTDDVYGTFADDFKSLFSvcP-------KNTILVYSYSKYFGATGWRL 322
Cdd:PRK05957 167 ISPNNPTGVVYPEALLRAVNQICAEHG--IYHISDEAYEYFTYDGVKHFS--PgsipgsgNHTISLYSLSKAYGFASWRI 242
|
.
gi 490580942 323 G 323
Cdd:PRK05957 243 G 243
|
|
| PRK05166 |
PRK05166 |
histidinol-phosphate transaminase; |
193-323 |
1.89e-03 |
|
histidinol-phosphate transaminase;
Pssm-ID: 179950 Cd Length: 371 Bit Score: 40.51 E-value: 1.89e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 193 DKVAIGMPVFTPYIEIPQLDAYGLEEVSISadPEAGWQYPDSELEKLKDPsiKIFFCINPSNPPSVKLDQRSLEKIADIV 272
Cdd:PRK05166 113 DRVVTLYPSFPLHEDYPTMMGARVERVTVT--PDLGFDLDALCAAVARAP--RMLMFSNPSNPVGSWLTADQLARVLDAT 188
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 490580942 273 DnhrPDLMILTDDVYGTFA--DDFKS---LFSVCPKNTILVYSYSKYFGATGWRLG 323
Cdd:PRK05166 189 P---PETLIVVDEAYAEYAagDDYPSaltLLKARGLPWIVLRTFSKAYGLAGLRVG 241
|
|
| PRK07777 |
PRK07777 |
putative succinyldiaminopimelate transaminase DapC; |
252-323 |
4.84e-03 |
|
putative succinyldiaminopimelate transaminase DapC;
Pssm-ID: 236095 [Multi-domain] Cd Length: 387 Bit Score: 39.25 E-value: 4.84e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490580942 252 PSNPPSVKLDQRSLEKIADIVDNHrpDLMILTDDVYG--TFADDFKSLFSVCP---KNTILVYSYSKYFGATGWRLG 323
Cdd:PRK07777 168 PHNPTGTVLTAAELAAIAELAVEH--DLLVITDEVYEhlVFDGARHLPLATLPgmrERTVTISSAAKTFNVTGWKIG 242
|
|
| PRK08354 |
PRK08354 |
putative aminotransferase; Provisional |
188-323 |
6.53e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 169399 Cd Length: 311 Bit Score: 38.94 E-value: 6.53e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 188 LIKKSDKVAIGMPVFTPYIEIPQLdaYGLEEVSISADPEagwqypdsELEKLKDPSIKIFFCiNPSNPPSVKLDQRSLEK 267
Cdd:PRK08354 73 LALRDRKVIIPRHTYGEYERVARF--FAARIIKGPNDPE--------KLEELVERNSVVFFC-NPNNPDGKFYNFKELKP 141
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 490580942 268 IADIVDNHRPdlMILTDDVYGTFADDFKSlfsVCPKNTILVYSYSKYFGATGWRLG 323
Cdd:PRK08354 142 LLDAVEDRNA--LLILDEAFIDFVKKPES---PEGENIIKLRTFTKSYGLPGIRVG 192
|
|
| PRK12414 |
PRK12414 |
putative aminotransferase; Provisional |
188-323 |
8.30e-03 |
|
putative aminotransferase; Provisional
Pssm-ID: 183514 Cd Length: 384 Bit Score: 38.62 E-value: 8.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490580942 188 LIKKSDKVAIGMPVFTPYIEIPQLDayGLEEVSISADPE---AGWqypdSELEKLKDPSIKIFFCINPSNPPSVKLDQRS 264
Cdd:PRK12414 110 LVHPGDEVIYFEPSFDSYAPIVRLQ--GATPVAIKLSPEdfrVNW----DEVAAAITPRTRMIIVNTPHNPSATVFSAAD 183
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490580942 265 LEKIADIVDNhrPDLMILTDDVYGTFADDFKSLFSVC-----PKNTILVYSYSKYFGATGWRLG 323
Cdd:PRK12414 184 LARLAQLTRN--TDIVILSDEVYEHVVFDGARHHSMArhrelAERSVIVSSFGKSYHVTGWRVG 245
|
|
| |
