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Conserved domains on  [gi|490589361|ref|WP_004454381|]
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pyrimidine dimer DNA glycosylase/endonuclease V [Clostridioides difficile]

Protein Classification

pyrimidine dimer DNA glycosylase/endonuclease V( domain architecture ID 10503354)

pyrimidine dimer DNA glycosylase/endonuclease V participates in the repair of UV-damaged DNA by excising pyrimidine dimers that are the major UV-lesions, and has DNA glycosylase activity, hydrolyzing the glycosylic bond of the 5' pyrimidine of the dimer

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pyr_excise pfam03013
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-77 1.86e-16

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


:

Pssm-ID: 460778  Cd Length: 81  Bit Score: 69.63  E-value: 1.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589361    1 MRLWH---KDLIDVLPKNQLVSQWRELLAIKGSI--DKKGTPNHLLVNKVLNYsIDEFKFYTKIVHDEMLKRNYKPNELK 75
Cdd:pfam03013   1 MRLWNlhpEDSAEYLDRQHLLAQHRELLQIFGVLlgEKKGYRNHPHVKRFYGY-LEALAQYHLALVEEMTRRGYNFNRPW 79


                  ..
gi 490589361   76 YT 77
Cdd:pfam03013  80 ID 81
 
Name Accession Description Interval E-value
Pyr_excise pfam03013
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-77 1.86e-16

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


Pssm-ID: 460778  Cd Length: 81  Bit Score: 69.63  E-value: 1.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589361    1 MRLWH---KDLIDVLPKNQLVSQWRELLAIKGSI--DKKGTPNHLLVNKVLNYsIDEFKFYTKIVHDEMLKRNYKPNELK 75
Cdd:pfam03013   1 MRLWNlhpEDSAEYLDRQHLLAQHRELLQIFGVLlgEKKGYRNHPHVKRFYGY-LEALAQYHLALVEEMTRRGYNFNRPW 79


                  ..
gi 490589361   76 YT 77
Cdd:pfam03013  80 ID 81
 
Name Accession Description Interval E-value
Pyr_excise pfam03013
Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers ...
 1-77 1.86e-16

Pyrimidine dimer DNA glycosylase; Pyrimidine dimer DNA glycosylases excise pyrimidine dimers by hydrolysis of the glycosylic bond of the 5' pyrimidine, followed by the intra-pyrimidine phosphodiester bond. Pyrimidine dimers are the major UV-lesions of DNA.


Pssm-ID: 460778  Cd Length: 81  Bit Score: 69.63  E-value: 1.86e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589361    1 MRLWH---KDLIDVLPKNQLVSQWRELLAIKGSI--DKKGTPNHLLVNKVLNYsIDEFKFYTKIVHDEMLKRNYKPNELK 75
Cdd:pfam03013   1 MRLWNlhpEDSAEYLDRQHLLAQHRELLQIFGVLlgEKKGYRNHPHVKRFYGY-LEALAQYHLALVEEMTRRGYNFNRPW 79


                  ..
gi 490589361   76 YT 77
Cdd:pfam03013  80 ID 81
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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