|
Name |
Accession |
Description |
Interval |
E-value |
| PepP |
COG0006 |
Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; |
7-357 |
1.52e-106 |
|
Xaa-Pro aminopeptidase [Amino acid transport and metabolism];
Pssm-ID: 439777 [Multi-domain] Cd Length: 299 Bit Score: 314.45 E-value: 1.52e-106
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 7 VVELLETKGVDALYLTKKTNVNYISGFPD---EEAYAVICKDGN-FLVTDSRYMElaekvckdfeiinwhnfdrsvakav 82
Cdd:COG0006 3 LRALMAEAGLDALLLTDPSNFAYLTGFRGspeRLAALLVTADGEpVLFVDELEAE------------------------- 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 83 ksvcdkvgikklgfertnivfdkyeelknliekdnGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHIKA 162
Cdd:COG0006 58 -----------------------------------RELVDASDLLEELRAIKSPEEIELMRKAARIADAAHEAALAALRP 102
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 163 GVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEK 242
Cdd:COG0006 103 GVTEREVAAELEAAMRRRGAEGPSFDTIVASGENAAIPHYTPTDRPLKPGDLVLIDAGAEYDGYTSDITRTVAVGEPSDE 182
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 243 QLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVGRDVHEEPFIGNYGDKIIEEGCIITME 320
Cdd:COG0006 183 QREIYEAVLEAQEAAIAALKPGVTGGEVDAAARDVLAEagYGEYFPHGTGHGVGLDVHEGPQISPGNDRPLEPGMVFTIE 262
|
330 340 350
....*....|....*....|....*....|....*..
gi 490589630 321 PGIYFPGWGGVRIEDTVLITKNGPERLTKFPKDLMIL 357
Cdd:COG0006 263 PGIYIPGIGGVRIEDTVLVTEDGAEVLTRLPRELLEL 299
|
|
| APP-like |
cd01092 |
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse ... |
139-344 |
3.78e-94 |
|
Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline.
Pssm-ID: 238525 [Multi-domain] Cd Length: 208 Bit Score: 279.39 E-value: 3.78e-94
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 139 IKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLID 218
Cdd:cd01092 1 IELLRKAARIADKAFEELLEFIKPGMTEREVAAELEYFMRKLGAEGPSFDTIVASGPNSALPHGVPSDRKIEEGDLVLID 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 219 YGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVV--KKYEDYYYQGIGHGVGRD 296
Cdd:cd01092 81 FGAIYDGYCSDITRTVAVGEPSDELKEIYEIVLEAQQAAIKAVKPGVTAKEVDKAARDVIeeAGYGEYFIHRTGHGVGLE 160
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 490589630 297 VHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIEDTVLITKNGP 344
Cdd:cd01092 161 VHEAPYISPGSDDVLEEGMVFTIEPGIYIPGKGGVRIEDDVLVTEDGC 208
|
|
| Peptidase_M24 |
pfam00557 |
Metallopeptidase family M24; This family contains metallopeptidases. It also contains ... |
143-341 |
6.19e-77 |
|
Metallopeptidase family M24; This family contains metallopeptidases. It also contains non-peptidase homologs such as the N terminal domain of Spt16 which is a histone H3-H4 binding module.
Pssm-ID: 459852 [Multi-domain] Cd Length: 208 Bit Score: 235.60 E-value: 6.19e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYF-MKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGA 221
Cdd:pfam00557 4 RKAARIAAAALEAALAAIRPGVTERELAAELEAArLRRGGARGPAFPPIVASGPNAAIPHYIPNDRVLKPGDLVLIDVGA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 222 MYN-GYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVGRDVH 298
Cdd:pfam00557 84 EYDgGYCSDITRTFVVGKPSPEQRELYEAVLEAQEAAIAAVKPGVTGGDVDAAAREVLEEagLGEYFPHGLGHGIGLEVH 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 490589630 299 EEPFIGNYGDK-IIEEGCIITMEPGIYF-PGWGGVRIEDTVLITK 341
Cdd:pfam00557 164 EGPYISRGGDDrVLEPGMVFTIEPGIYFiPGWGGVRIEDTVLVTE 208
|
|
| PRK09795 |
PRK09795 |
aminopeptidase; Provisional |
1-356 |
4.12e-73 |
|
aminopeptidase; Provisional
Pssm-ID: 182080 [Multi-domain] Cd Length: 361 Bit Score: 230.98 E-value: 4.12e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 1 MSRVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYAVICKDGNFLVTDSRYMELAEKVCKDFEIinwHNFD--RSV 78
Cdd:PRK09795 1 MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYADVEARAQGYQL---HLLDatNTL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 79 AKAVKSVCDKVGIKKLGFERTNIVFDKYEELKnliEKDNGELIPTEniVETLRYVKDKDEIKNTRKACEIADKALEELIP 158
Cdd:PRK09795 78 TTIVNQIIADEQLQTLGFEGQQVSWETAHRWQ---SELNAKLVSAT--PDVLRQIKTPEEVEKIRLACGIADRGAEHIRR 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 159 HIKAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGG 238
Cdd:PRK09795 153 FIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNG 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 239 ASEKQ-----LEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVGRDVHEEPFIGNYGDKII 311
Cdd:PRK09795 233 EGVSAeshplFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEagYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTL 312
|
330 340 350 360
....*....|....*....|....*....|....*....|....*
gi 490589630 312 EEGCIITMEPGIYFPGWGGVRIEDTVLITKNGPERLTKFPKDLMI 356
Cdd:PRK09795 313 QPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLL 357
|
|
| APP_MetAP |
cd01066 |
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as ... |
143-344 |
4.05e-61 |
|
A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity compared to other metallo-aminopeptidases, suggesting they play roles in regulation of biological processes rather than general protein degradation.
Pssm-ID: 238514 [Multi-domain] Cd Length: 207 Bit Score: 194.98 E-value: 4.05e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQnIGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAM 222
Cdd:cd01066 5 RKAAEIAEAAMAAAAEAIRPGVTEAEVAAAIEQALRAAGGY-PAGPTIVGSGARTALPHYRPDDRRLQEGDLVLVDLGGV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 223 YNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVGRDVHEE 300
Cdd:cd01066 84 YDGYHADLTRTFVIGEPSDEQRELYEAVREAQEAALAALRPGVTAEEVDAAAREVLEEhgLGPNFGHRTGHGIGLEIHEP 163
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 490589630 301 PFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIEDTVLITKNGP 344
Cdd:cd01066 164 PVLKAGDDTVLEPGMVFAVEPGLYLPGGGGVRIEDTVLVTEDGP 207
|
|
| Prolidase |
cd01087 |
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline ... |
143-349 |
3.92e-51 |
|
Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.
Pssm-ID: 238520 [Multi-domain] Cd Length: 243 Bit Score: 170.45 E-value: 3.92e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNiGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAM 222
Cdd:cd01087 5 RKACDISAEAHRAAMKASRPGMSEYELEAEFEYEFRSRGARL-AYSYIVAAGSNAAILHYVHNDQPLKDGDLVLIDAGAE 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 223 YNGYISDTTRTFIVGGA-SEKQLEIYNLVKEAQNVGVENMKAGV-HATIPDAEIRKVVKK-------------------Y 281
Cdd:cd01087 84 YGGYASDITRTFPVNGKfTDEQRELYEAVLAAQKAAIAACKPGVsYEDIHLLAHRVLAEGlkelgilkgdvdeivesgaY 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 282 EDYYYQGIGHGVGRDVH--EEPFIGNYGDKIIEEGCIITMEPGIYFPGW----------GGVRIEDTVLITKNGPERLTK 349
Cdd:cd01087 164 AKFFPHGLGHYLGLDVHdvGGYLRYLRRARPLEPGMVITIEPGIYFIPDlldvpeyfrgGGIRIEDDVLVTEDGPENLTR 243
|
|
| Map |
COG0024 |
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis]; |
132-353 |
1.41e-39 |
|
Methionine aminopeptidase [Translation, ribosomal structure and biogenesis];
Pssm-ID: 439795 [Multi-domain] Cd Length: 250 Bit Score: 140.53 E-value: 1.41e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 132 YVKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAqnigfetilISGAK----------TSL-- 199
Cdd:COG0024 2 EIKTPEEIEKMREAGRIVAEVLDELAEAVKPGVTTLELDRIAEEFIRDHGA---------IPAFLgyygfpksicTSVne 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 200 --LHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHatIPD--AEIR 275
Cdd:COG0024 73 vvVHGIPSDRVLKDGDIVNIDVGAILDGYHGDSARTFVVGEVSPEARRLVEVTEEALYAGIAAAKPGNR--LGDigHAIQ 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 276 KVVKKY-----EDYyyqgIGHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEP-------GIYFP--GWgGVRIED-- 335
Cdd:COG0024 151 SYAESNgysvvREF----VGHGIGREMHEEPQVPNYGRPgrgpRLKPGMVLAIEPminagtpEVKVLddGW-TVVTKDgs 225
|
250 260
....*....|....*....|....*
gi 490589630 336 -------TVLITKNGPERLTKFPKD 353
Cdd:COG0024 226 lsaqfehTVAVTEDGPEILTLPDGG 250
|
|
| PRK05716 |
PRK05716 |
methionine aminopeptidase; Validated |
133-353 |
3.84e-38 |
|
methionine aminopeptidase; Validated
Pssm-ID: 235576 [Multi-domain] Cd Length: 252 Bit Score: 136.80 E-value: 3.84e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 133 VKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELatkleyfmkmngaQNIGFETILISGAKTSLL------------ 200
Cdd:PRK05716 5 IKTPEEIEKMRVAGRLAAEVLDEIEPHVKPGVTTKEL-------------DRIAEEYIRDQGAIPAPLgyhgfpksicts 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 201 ------HGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEI 274
Cdd:PRK05716 72 vnevvcHGIPSDKVLKEGDIVNIDVTVIKDGYHGDTSRTFGVGEISPEDKRLCEVTKEALYLGIAAVKPGARLGDIGHAI 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 275 RKVVKKY-----EDYyyqgIGHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEP----GIYFP-----GWGGV----- 331
Cdd:PRK05716 152 QKYAEAEgfsvvREY----CGHGIGRKFHEEPQIPHYGAPgdgpVLKEGMVFTIEPminaGKREVktlkdGWTVVtkdgs 227
|
250 260
....*....|....*....|....*
gi 490589630 332 ---RIEDTVLITKNGPERLTKFPKD 353
Cdd:PRK05716 228 lsaQYEHTVAVTEDGPEILTLRPEE 252
|
|
| met_pdase_I |
TIGR00500 |
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. ... |
132-349 |
8.77e-37 |
|
methionine aminopeptidase, type I; Methionine aminopeptidase is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. This model describes type I. The role of this protein in general is to produce the mature form of cytosolic proteins by removing the N-terminal methionine. [Protein fate, Protein modification and repair]
Pssm-ID: 129591 [Multi-domain] Cd Length: 247 Bit Score: 133.24 E-value: 8.77e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 132 YVKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQN-----IGFETILISGAKTSLLHGKPSD 206
Cdd:TIGR00500 2 SLKSPDEIEKIRKAGRLAAEVLEELEREVKPGVSTKELDRIAKDFIEKHGAKPaflgyYGFPGSVCISVNEVVIHGIPDK 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 207 KIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGvhatIPDAEIRKVVKKY-EDYY 285
Cdd:TIGR00500 82 KVLKDGDIVNIDVGVIYDGYHGDTAKTFLVGKISPEAEKLLECTEESLYKAIEEAKPG----NRIGEIGAAIQKYaEAKG 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 286 YQGI----GHGVGRDVHEEPFIGNYGDKI----IEEGCIITMEPGIYFPGWGGV-----------------RIEDTVLIT 340
Cdd:TIGR00500 158 FSVVreycGHGIGRKFHEEPQIPNYGKKFtnvrLKEGMVFTIEPMVNTGTEEITtaadgwtvktkdgslsaQFEHTIVIT 237
|
....*....
gi 490589630 341 KNGPERLTK 349
Cdd:TIGR00500 238 DNGPEILTE 246
|
|
| MetAP1 |
cd01086 |
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
139-349 |
1.28e-36 |
|
Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238519 [Multi-domain] Cd Length: 238 Bit Score: 132.23 E-value: 1.28e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 139 IKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQ-----NIGFE-TILISGAKTsLLHGKPSDKIIEKG 212
Cdd:cd01086 1 IEGMREAGRIVAEVLDELAKAIKPGVTTKELDQIAHEFIEEHGAYpaplgYYGFPkSICTSVNEV-VCHGIPDDRVLKDG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 213 DFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKKY-----EDYyyq 287
Cdd:cd01086 80 DIVNIDVGVELDGYHGDSARTFIVGEVSEEAKKLVEVTEEALYKGIEAVKPGNRIGDIGHAIEKYAEKNgysvvREF--- 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 288 gIGHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEP----GIYFP-----GWGGV--------RIEDTVLITKNGPER 346
Cdd:cd01086 157 -GGHGIGRKFHEEPQIPNYGRPgtgpKLKPGMVFTIEPminlGTYEVvtlpdGWTVVtkdgslsaQFEHTVLITEDGPEI 235
|
...
gi 490589630 347 LTK 349
Cdd:cd01086 236 LTL 238
|
|
| PRK10879 |
PRK10879 |
proline aminopeptidase P II; Provisional |
100-348 |
2.20e-33 |
|
proline aminopeptidase P II; Provisional
Pssm-ID: 182804 [Multi-domain] Cd Length: 438 Bit Score: 128.30 E-value: 2.20e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 100 NIVFDKYEEL-----KNLieKDNGELIPTENIVETLRYVKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLE 174
Cdd:PRK10879 137 EIVFSALEKLrkgsrQNL--TAPATLTDWRPWVHEMRLFKSPEEIAVLRRAGEISALAHTRAMEKCRPGMFEYQLEGEIH 214
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 175 YFMKMNGAQNIGFETILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGA-SEKQLEIYNLVKEA 253
Cdd:PRK10879 215 HEFNRHGARYPSYNTIVGSGENGCILHYTENESEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKfTPAQREIYDIVLES 294
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 254 QNVGVENMKAG------------------VHATIPDAEIRKVV--KKYEDYYYQGIGHGVGRDVHEepfIGNYG---DKI 310
Cdd:PRK10879 295 LETSLRLYRPGtsirevtgevvrimvsglVKLGILKGDVDQLIaeNAHRPFFMHGLSHWLGLDVHD---VGVYGqdrSRI 371
|
250 260 270 280
....*....|....*....|....*....|....*....|....*...
gi 490589630 311 IEEGCIITMEPGIY----------FPGWgGVRIEDTVLITKNGPERLT 348
Cdd:PRK10879 372 LEPGMVLTVEPGLYiapdadvpeqYRGI-GIRIEDDIVITETGNENLT 418
|
|
| PRK12896 |
PRK12896 |
methionine aminopeptidase; Reviewed |
133-348 |
1.02e-28 |
|
methionine aminopeptidase; Reviewed
Pssm-ID: 237252 [Multi-domain] Cd Length: 255 Bit Score: 111.85 E-value: 1.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 133 VKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNI-----GF-ETILISgAKTSLLHGKPSD 206
Cdd:PRK12896 10 IKSPRELEKMRKIGRIVATALKEMGKAVEPGMTTKELDRIAEKRLEEHGAIPSpegyyGFpGSTCIS-VNEEVAHGIPGP 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 207 KIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEkqlEIYNLV---KEAQNVGVENMKAGVHATIPDAEIRKVVKKY-- 281
Cdd:PRK12896 89 RVIKDGDLVNIDVSAYLDGYHGDTGITFAVGPVSE---EAEKLCrvaEEALWAGIKQVKAGRPLNDIGRAIEDFAKKNgy 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 282 ---EDYyyqgIGHGVGRDVHEEP-FIGNYGDK----IIEEGCIITMEP----GIYF-----PGWG--------GVRIEDT 336
Cdd:PRK12896 166 svvRDL----TGHGVGRSLHEEPsVILTYTDPlpnrLLRPGMTLAVEPflnlGAKDaetldDGWTvvtpdkslSAQFEHT 241
|
250
....*....|..
gi 490589630 337 VLITKNGPERLT 348
Cdd:PRK12896 242 VVVTRDGPEILT 253
|
|
| Creatinase_N |
pfam01321 |
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic ... |
3-133 |
5.20e-28 |
|
Creatinase/Prolidase N-terminal domain; This family includes the N-terminal non-catalytic domains from creatinase and prolidase. The exact function of this domain is uncertain.
Pssm-ID: 460159 Cd Length: 128 Bit Score: 106.23 E-value: 5.20e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 3 RVKNVVELLETKGVDALYLTKKTNVNYISGFPDEEAYA-VICKDGNFLVTD-SRYMELAEKVCKDFEIINWHNFdRSVAK 80
Cdd:pfam01321 1 RLEKLRKLMEEKGLDAALVTSPENLRYLTGFTGSRGLLlLVTADGALLLVDaLEYERAAAESAPDFDVVPYRDY-EALAD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 490589630 81 AVKSVCdkVGIKKLGFERTNIVFDKYEELKNLIEKDngELIPTENIVETLRYV 133
Cdd:pfam01321 80 LLKELG--AGGKRVGFEADALTVAFYEALKEALPGA--ELVDVSGLIERLRMV 128
|
|
| APP |
cd01085 |
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline ... |
164-343 |
1.30e-27 |
|
X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.
Pssm-ID: 238518 [Multi-domain] Cd Length: 224 Bit Score: 108.03 E-value: 1.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 164 VSEIELATKLEYFMKMNGAQ-NIGFETILISGAKTSLLHGKP---SDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGA 239
Cdd:cd01085 30 ITELSAADKLEEFRRQQKGYvGLSFDTISGFGPNGAIVHYSPteeSNRKISPDGLYLIDSGGQYLDGTTDITRTVHLGEP 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 240 SEKQLEIYNLVKEAqNVGVENMK--AGVHATIPDAEIRKVVKKYEDYYYQGIGHGVGR--DVHEEP--FIGNYGDKIIEE 313
Cdd:cd01085 110 TAEQKRDYTLVLKG-HIALARAKfpKGTTGSQLDALARQPLWKAGLDYGHGTGHGVGSflNVHEGPqsISPAPNNVPLKA 188
|
170 180 190
....*....|....*....|....*....|
gi 490589630 314 GCIITMEPGIYFPGWGGVRIEDTVLITKNG 343
Cdd:cd01085 189 GMILSNEPGYYKEGKYGIRIENLVLVVEAE 218
|
|
| PRK15173 |
PRK15173 |
peptidase; Provisional |
72-355 |
1.24e-21 |
|
peptidase; Provisional
Pssm-ID: 185095 [Multi-domain] Cd Length: 323 Bit Score: 94.01 E-value: 1.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 72 HNFDRSVAKAVKSVCD---------KVGIKKLGFErTNIVFDKYEELKNLIeKDNGELIPTENIVETLRYVKDKDEIKNT 142
Cdd:PRK15173 27 NNKERPIGPPIESVCNilkdalndaRVLNKKIAID-LNIMSNGGKRVIDAV-MPNVDFVDSSSIFNELRVIKSPWEIKRL 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTS--LLhgkPSDKIIEKGDFVLIDYG 220
Cdd:PRK15173 105 RKSAEITEYGITEASKLIRVGCTSAELTAAYKAAVMSKSETHFSRFHLISVGADFSpkLI---PSNTKACSGDLIKFDCG 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 221 AMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVG--RD 296
Cdd:PRK15173 182 VDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTMEVIKKsgLPNYNRGHLGHGNGvfLG 261
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 490589630 297 VHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIEDTVLITKNGPERLTKFPKDLM 355
Cdd:PRK15173 262 LEESPFVSTHATESFTSGMVLSLETPYYGYNLGSIMIEDMILINKEGIEFLSKLPRDLV 320
|
|
| PRK14575 |
PRK14575 |
putative peptidase; Provisional |
72-355 |
5.67e-21 |
|
putative peptidase; Provisional
Pssm-ID: 173039 [Multi-domain] Cd Length: 406 Bit Score: 93.23 E-value: 5.67e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 72 HNFDRSVAKAVKSVCD---------KVGIKKLGFErTNIVFDKYEELKNLIeKDNGELIPTENIVETLRYVKDKDEIKNT 142
Cdd:PRK14575 110 NNKERPIGPPIESVCNilkdalndaRVLNKKIAID-LNIMSNGGKRVIDAV-MPNVDFVDSSSIFNELRVIKSPWEIKRL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTS--LLhgkPSDKIIEKGDFVLIDYG 220
Cdd:PRK14575 188 RKSAEITEYGITEASKLIRVGCTSAELTAAYKAAVMSKSETHFSRFHLISVGADFSpkLI---PSNTKACSGDLIKFDCG 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 221 AMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKK--YEDYYYQGIGHGVG--RD 296
Cdd:PRK14575 265 VDVDGYGADIARTFVVGEPPEITRKIYQTIRTGHEHMLSMVAPGVKMKDVFDSTMEVIKKsgLPNYNRGHLGHGNGvfLG 344
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*....
gi 490589630 297 VHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIEDTVLITKNGPERLTKFPKDLM 355
Cdd:PRK14575 345 LEESPFVSTHATESFTSGMVLSLETPYYGYNLGSIMIEDMILINKEGIEFLSKLPRDLV 403
|
|
| PRK12897 |
PRK12897 |
type I methionyl aminopeptidase; |
133-350 |
3.77e-20 |
|
type I methionyl aminopeptidase;
Pssm-ID: 171806 Cd Length: 248 Bit Score: 88.17 E-value: 3.77e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 133 VKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNI-----GFETILISGAKTSLLHGKPSDK 207
Cdd:PRK12897 4 IKTKNEIDLMHESGKLLASCHREIAKIMKPGITTKEINTFVEAYLEKHGATSEqkgynGYPYAICASVNDEMCHAFPADV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 208 IIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHAtipdAEIRKVVKKY------ 281
Cdd:PRK12897 84 PLTEGDIVTIDMVVNLNGGLSDSAWTYRVGKVSDEAEKLLLVAENALYKGIDQAVIGNRV----GDIGYAIESYvanegf 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 282 ---EDYyyqgIGHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEP----GIYFP-----GWGG--------VRIEDTV 337
Cdd:PRK12897 160 svaRDF----TGHGIGKEIHEEPAIFHFGKQgqgpELQEGMVITIEPivnvGMRYSkvdlnGWTArtmdgklsAQYEHTI 235
|
250
....*....|...
gi 490589630 338 LITKNGPERLTKF 350
Cdd:PRK12897 236 AITKDGPIILTKL 248
|
|
| PRK12318 |
PRK12318 |
methionyl aminopeptidase; |
133-348 |
9.61e-19 |
|
methionyl aminopeptidase;
Pssm-ID: 183434 [Multi-domain] Cd Length: 291 Bit Score: 85.26 E-value: 9.61e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 133 VKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGA----QNIG---FETILISGAKTSLLHGKPS 205
Cdd:PRK12318 43 IKTPEQIEKIRKACQVTARILDALCEAAKEGVTTNELDELSRELHKEYNAipapLNYGsppFPKTICTSLNEVICHGIPN 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 206 DKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGvhatIPDAEIRKVVKKYEDYY 285
Cdd:PRK12318 123 DIPLKNGDIMNIDVSCIVDGYYGDCSRMVMIGEVSEIKKKVCQASLECLNAAIAILKPG----IPLYEIGEVIENCADKY 198
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 286 -----YQGIGHGVGRDVHEEPFIGNYGDK---IIEEGCIITMEP--------GIYFP----------GWGGVRIEDTVLI 339
Cdd:PRK12318 199 gfsvvDQFVGHGVGIKFHENPYVPHHRNSskiPLAPGMIFTIEPminvgkkeGVIDPinhweartcdNQPSAQWEHTILI 278
|
....*....
gi 490589630 340 TKNGPERLT 348
Cdd:PRK12318 279 TETGYEILT 287
|
|
| MetAP2 |
cd01088 |
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and ... |
143-321 |
6.92e-18 |
|
Methionine Aminopeptidase 2. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.
Pssm-ID: 238521 [Multi-domain] Cd Length: 291 Bit Score: 82.68 E-value: 6.92e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQnIGFETILisgaktSLLH-------GKPSDKIIEKGDFV 215
Cdd:cd01088 5 REAGEIHRQVRKYAQSLIKPGMTLLEIAEFVENRIRELGAG-PAFPVNL------SINEcaahytpNAGDDTVLKEGDVV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 216 LIDYGAMYNGYISDTTRTFIVGGASEKQLEIynlVKEAQNVGVENMKAGVHATIPDAEIRKVVkkyEDYYYQGI----GH 291
Cdd:cd01088 78 KLDFGAHVDGYIADSAFTVDFDPKYDDLLEA---AKEALNAAIKEAGPDVRLGEIGEAIEEVI---ESYGFKPIrnltGH 151
|
170 180 190
....*....|....*....|....*....|....
gi 490589630 292 GVGR-DVHEEPFIGNY---GDKIIEEGCIITMEP 321
Cdd:cd01088 152 SIERyRLHAGKSIPNVkggEGTRLEEGDVYAIEP 185
|
|
| PRK14576 |
PRK14576 |
putative endopeptidase; Provisional |
10-354 |
2.37e-16 |
|
putative endopeptidase; Provisional
Pssm-ID: 173040 [Multi-domain] Cd Length: 405 Bit Score: 79.67 E-value: 2.37e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 10 LLETKGVDALYLTKKTNVNYISGFPD---------EEAYAVICKDGNF--------LVTDSRYMELAEKVCKDFEII--- 69
Cdd:PRK14576 19 VMEREGIDALVVTVCDNFYYLTGFASffmytfrhtGAAVAIMFRDANIpsqiimneFEAASTHFDMPNSVLKTFPVWvdv 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 70 ----NWHNF----DRSVAKAVKSVcdkVGIKKLGFERTNiVFDKYEELKnLIEKDNG------------ELIPTENIVET 129
Cdd:PRK14576 99 ddprNPHHHykkrDRPIGPPVEAV---FSLVKNALEDAG-VLDKTIAIE-LQAMSNGgkgvldkvapglKLVDSTALFNE 173
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 130 LRYVKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNIGFETILISGAKTSLlHGKPSDKII 209
Cdd:PRK14576 174 IRMIKSPWEIEHLRKSAEITEYGIASAAKKIRVGCTAAELTAAFKAAVMSFPETNFSRFNLISVGDNFSP-KIIADTTPA 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 210 EKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVH-ATIPDAEIRKVVKKYEDYYYQG 288
Cdd:PRK14576 253 KVGDLIKFDCGIDVAGYGADLARTFVLGEPDKLTQQIYDTIRTGHEHMLSMVAPGVKlKAVFDSTMAVIKTSGLPHYNRG 332
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 490589630 289 -IGHGVG--RDVHEEPFIGNYGDKIIEEGCIITMEPGIYFPGWGGVRIEDTVLITKNGPERLTKFPKDL 354
Cdd:PRK14576 333 hLGHGDGvfLGLEEVPFVSTQATETFCPGMVLSLETPYYGIGVGSIMLEDMILITDSGFEFLSKLDRDL 401
|
|
| PRK13607 |
PRK13607 |
proline dipeptidase; Provisional |
216-348 |
4.98e-14 |
|
proline dipeptidase; Provisional
Pssm-ID: 237444 [Multi-domain] Cd Length: 443 Bit Score: 72.62 E-value: 4.98e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 216 LIDYGAMYNGYISDTTRTFivggASEKQLEIYNLVK---EAQNVGVENMKAGV---------HatipdAEIRKVVKKY-- 281
Cdd:PRK13607 244 LIDAGAEYNGYAADITRTY----AAKEDNDFAALIKdvnKEQLALIATMKPGVsyvdlhiqmH-----QRIAKLLRKFqi 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 282 ------EDYYYQGI---------GHGVGRDVH------------------EEPFIGNygDKIIEEGCIITMEPGIYF--- 325
Cdd:PRK13607 315 vtglseEAMVEQGItspffphglGHPLGLQVHdvagfmqddrgthlaapeKHPYLRC--TRVLEPGMVLTIEPGLYFids 392
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 490589630 326 -----------------------PgWGGVRIEDTVLITKNGPERLT 348
Cdd:PRK13607 393 llaplregpfskhfnwqkidalkP-FGGIRIEDNVVVHENGVENMT 437
|
|
| Creatinase |
cd01090 |
Creatine amidinohydrolase. E.C.3.5.3.3. Hydrolyzes creatine to sarcosine and urea. |
139-349 |
7.31e-14 |
|
Creatine amidinohydrolase. E.C.3.5.3.3. Hydrolyzes creatine to sarcosine and urea.
Pssm-ID: 238523 [Multi-domain] Cd Length: 228 Bit Score: 70.26 E-value: 7.31e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 139 IKNTRKACEIADKALEELIphiKAGVSEIELATKLEYFMKMNGAQNIGFE------TILISGAKTSLLHGKPSDKIIEKG 212
Cdd:cd01090 4 IRHGARIADIGGAAVVEAI---REGVPEYEVALAGTQAMVREIAKTFPEVelmdtwTWFQSGINTDGAHNPVTNRKVQRG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 213 DFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGVHATIPDAEIRKVVKKYEDYYYQ--GIG 290
Cdd:cd01090 81 DILSLNCFPMIAGYYTALERTLFLDEVSDAHLKIWEANVAVHERGLELIKPGARCKDIAAELNEMYREHDLLRYRtfGYG 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490589630 291 HGVGRDVHEepfignYG-----------DKIIEEGCIITMEPGIYF----PGWGGVRIEDTVLITKNGPERLTK 349
Cdd:cd01090 161 HSFGVLSHY------YGreaglelrediDTVLEPGMVVSMEPMIMLpegqPGAGGYREHDILVINENGAENITG 228
|
|
| PLN03158 |
PLN03158 |
methionine aminopeptidase; Provisional |
124-349 |
9.23e-14 |
|
methionine aminopeptidase; Provisional
Pssm-ID: 215607 [Multi-domain] Cd Length: 396 Bit Score: 71.79 E-value: 9.23e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 124 ENIVEtlryVKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIEL------AT--------KLEYFMkmngaqnigFET 189
Cdd:PLN03158 132 QHSVE----IKTPEQIQRMRETCRIAREVLDAAARAIKPGVTTDEIdrvvheATiaaggypsPLNYHF---------FPK 198
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 190 ILISGAKTSLLHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVENMKAGV---- 265
Cdd:PLN03158 199 SCCTSVNEVICHGIPDARKLEDGDIVNVDVTVYYKGCHGDLNETFFVGNVDEASRQLVKCTYECLEKAIAIVKPGVryre 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 266 -------HATIPDAEirkVVKKYedyyyqgIGHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEPGI--------YFP 326
Cdd:PLN03158 279 vgevinrHATMSGLS---VVKSY-------CGHGIGELFHCAPNIPHYARNkavgVMKAGQVFTIEPMInagvwrdrMWP 348
|
250 260 270
....*....|....*....|....*....|..
gi 490589630 327 -GWGGV--------RIEDTVLITKNGPERLTK 349
Cdd:PLN03158 349 dGWTAVtadgkrsaQFEHTLLVTETGVEVLTA 380
|
|
| PRK07281 |
PRK07281 |
methionyl aminopeptidase; |
196-348 |
6.05e-09 |
|
methionyl aminopeptidase;
Pssm-ID: 180918 Cd Length: 286 Bit Score: 56.39 E-value: 6.05e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 196 KTSLLHGKPSDKI---IEKGDF----VLIDYGAMYNGYISDTTRTFIVGGASEKQLEIYNLVKEAQNVGVEnmKAGVHAT 268
Cdd:PRK07281 96 KVDMVLSEPLDKSivdVSKLNFdnveQMKKYTESYRGGLADSCWAYAVGTPSDEVKNLMDVTKEAMYRGIE--QAVVGNR 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 269 IPDaeIRKVVKKYEDYYYQGI-----GHGVGRDVHEEPFIGNYGDK----IIEEGCIITMEPGIYFPGW----------- 328
Cdd:PRK07281 174 IGD--IGAAIQEYAESRGYGVvrdlvGHGVGPTMHEEPMVPNYGTAgrglRLREGMVLTIEPMINTGTWeidtdmktgwa 251
|
170 180
....*....|....*....|....*..
gi 490589630 329 -----GGV--RIEDTVLITKNGPERLT 348
Cdd:PRK07281 252 hktldGGLscQYEHQFVITKDGPVILT 278
|
|
| met_pdase_II |
TIGR00501 |
methionine aminopeptidase, type II; Methionine aminopeptidase (map) is a cobalt-binding enzyme. ... |
144-321 |
8.65e-09 |
|
methionine aminopeptidase, type II; Methionine aminopeptidase (map) is a cobalt-binding enzyme. Bacterial and organellar examples (type I) differ from eukaroytic and archaeal (type II) examples in lacking a region of approximately 60 amino acids between the 4th and 5th cobalt-binding ligands. The role of this protein in general is to produce the mature amino end of cytosolic proteins by removing the N-terminal methionine. This model describes type II, among which the eukaryotic members typically have an N-terminal extension not present in archaeal members. It can act cotranslationally. The enzyme from rat has been shown to associate with translation initiation factor 2 (IF-2) and may have a role in translational regulation. [Protein fate, Protein modification and repair]
Pssm-ID: 129592 Cd Length: 295 Bit Score: 55.95 E-value: 8.65e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 144 KACEIADKALEELIPHIKAGVSEIELATKLEYFMKMNGAQNiGFETILISGAKTSLLHGKPSDK-IIEKGDFVLIDYGAM 222
Cdd:TIGR00501 10 EAGKIHSKVRREAADRIVPGVKLLEVAEFVENRIRELGAEP-AFPCNISINECAAHFTPKAGDKtVFKDGDVVKLDLGAH 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 223 YNGYISDTTRTFIVGGASEkqlEIYNLVKEAQNVGVENMKAGVHATipdaEIRKVVKK-YEDYYYQGI----GHGVGR-D 296
Cdd:TIGR00501 89 VDGYIADTAITVDLGDQYD---NLVKAAKDALYTAIKEIRAGVRVG----EIGKAIQEvIESYGVKPIsnltGHSMAPyR 161
|
170 180
....*....|....*....|....*...
gi 490589630 297 VHEEPFIGNYGDK---IIEEGCIITMEP 321
Cdd:TIGR00501 162 LHGGKSIPNVKERdttKLEEGDVVAIEP 189
|
|
| COG5406 |
COG5406 |
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and ... |
133-352 |
6.56e-05 |
|
Nucleosome binding factor SPN, SPT16 subunit [Transcription, Replication, recombination and repair, Chromatin structure and dynamics];
Pssm-ID: 227693 [Multi-domain] Cd Length: 1001 Bit Score: 45.00 E-value: 6.56e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 133 VKDKDEIKNTRKACEIADKALEELIPHIKAGVSEIELAT--KLEYFMKMNGAQNIGFET-------------------IL 191
Cdd:COG5406 170 TKDAEEIANCRASSAASSVLMRYFVKEMEMLWDGAFKIThgKLSDLMESLIDDVEFFQTkslklgdidldqlewcytpII 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 192 ISGAKTSLLHGKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEiYNLVKEAQNVGVENMKAGVHATIPD 271
Cdd:COG5406 250 QSGGSIDLTPSAFSFPMELTGDVVLLSIGIRYNGYCSNMSRTILTDPDSEQQKN-YEFLYMLQKYILGLVRPGTDSGIIY 328
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 272 AEIRKVVKK----YEDYYYQGIGHGVGRDVHEEPFIGNY-GDKIIEEGCIITMEPGI------YFPGWGGVRIEDTVLIT 340
Cdd:COG5406 329 SEAEKYISSngpeLGPNFIYNVGLMIGIEFRSSQKPFNVkNGRVLQAGCIFNISLGFgnlinpHPKNNYALLLIDTEQIS 408
|
250
....*....|..
gi 490589630 341 KNGPERLTKFPK 352
Cdd:COG5406 409 LSNPIVFTDSPK 420
|
|
| PA2G4-like |
cd01089 |
Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family ... |
143-348 |
4.25e-04 |
|
Related to aminopepdidase M, this family contains proliferation-associated protein 2G4. Family members have been implicated in cell cycle control.
Pssm-ID: 238522 Cd Length: 228 Bit Score: 41.16 E-value: 4.25e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 143 RKACEIADKALEELIPHIKAGVSEIELATK-----LEYFMKM-----NGAQNIGFETIlISGAKTsLLHGKP----SDKI 208
Cdd:cd01089 5 KTAGQIANKVLKQVISLCVPGAKVVDLCEKgdkliLEELGKVykkekKLEKGIAFPTC-ISVNNC-VCHFSPlksdATYT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 209 IEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLE--IYNLVKEAQNVgvenMKAGVHATIP---DAEIRKVV-KKYE 282
Cdd:cd01089 83 LKDGDVVKIDLGCHIDGYIAVVAHTIVVGAEAETPVTgkKADVIAAAHYA----LEAALRLLRPgnqNSDITEAIqKVIV 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 490589630 283 DYYYQGI----GHGVGRDVHEepfiGNYGDKIIE---EGCIITMEPGIYFPGWGGVRIEDTVLITKNGPERLT 348
Cdd:cd01089 159 DYGCTPVegvlSHQLKRVVSS----GEGKAKLVEcvkHGLLFPYPVLYEKEGEVVAQFKLTVLLTPNGVTVLT 227
|
|
| CDC68-like |
cd01091 |
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in ... |
139-347 |
4.98e-04 |
|
Related to aminopeptidase P and aminopeptidase M, a member of this domain family is present in cell division control protein 68, a transcription factor.
Pssm-ID: 238524 [Multi-domain] Cd Length: 243 Bit Score: 41.18 E-value: 4.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 139 IKNTRKACEIA----DKAL-EELIPHIKAG--VSEIELATKLEYFMKMNGAQNIGFET---------ILISGAKTSLL-H 201
Cdd:cd01091 1 LNNIKKASDATvdvlKKFFvDEVEEIIDQEkkVTHSKLSDKVEKAIEDKKKYKAKLDPeqldwcyppIIQSGGNYDLLkS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 202 GKPSDKIIEKGDFVLIDYGAMYNGYISDTTRTFIVgGASEKQLEIYNLVKEAQNVGVENMKAGvhATIPDA------EIR 275
Cdd:cd01091 81 SSSSDKLLYHFGVIICSLGARYKSYCSNIARTFLI-DPTSEQQKNYNFLLALQEEILKELKPG--AKLSDVyqktldYIK 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 276 KVVKKYEDYYYQGIGHGVGRDVHEEPF-IGNYGDKIIEEGCIITMEPGI---------------YfpgwgGVRIEDTVLI 339
Cdd:cd01091 158 KKKPELEPNFTKNLGFGIGLEFRESSLiINAKNDRKLKKGMVFNLSIGFsnlqnpepkdkesktY-----ALLLSDTILV 232
|
....*...
gi 490589630 340 TKNGPERL 347
Cdd:cd01091 233 TEDEPAIV 240
|
|
| crvDNA_42K |
TIGR00495 |
42K curved DNA binding protein; Proteins identified by this model have been identified in a ... |
145-244 |
5.19e-04 |
|
42K curved DNA binding protein; Proteins identified by this model have been identified in a number of species as a nuclear (but not nucleolar) protein with a cell cycle dependence. Various names given to members of this family have included cell cycle protein p38-2G4, DNA-binding protein GBP16, and proliferation-associated protein 1. This protein is closely related to methionine aminopeptidase, a cobolt-binding protein. [Unknown function, General]
Pssm-ID: 273105 Cd Length: 390 Bit Score: 41.80 E-value: 5.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 145 ACEIADKALEELIPHIKAGV----------SEIELATKLEYFMKMNGAQNIGFETILISG---AKTSLLHGKPsDKIIEK 211
Cdd:TIGR00495 26 AGEIANNVLKSVVEACSPGAkvvdicekgdAFIMEETAKIFKKEKEMEKGIAFPTCISVNncvGHFSPLKSDQ-DYILKE 104
|
90 100 110
....*....|....*....|....*....|...
gi 490589630 212 GDFVLIDYGAMYNGYISDTTRTFIVGGASEKQL 244
Cdd:TIGR00495 105 GDVVKIDLGCHIDGFIALVAHTFVVGVAQEEPV 137
|
|
| PTZ00053 |
PTZ00053 |
methionine aminopeptidase 2; Provisional |
137-282 |
1.39e-03 |
|
methionine aminopeptidase 2; Provisional
Pssm-ID: 240246 [Multi-domain] Cd Length: 470 Bit Score: 40.47 E-value: 1.39e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 137 DEIKNTRKACEIADKALEELIPHIKAGVSEIELATKLE----YFMKMNGAQ-NIGFETILisgaktSLLH------GKPS 205
Cdd:PTZ00053 156 EQYQDLRRAAEVHRQVRRYAQSVIKPGVKLIDICERIEsksrELIEADGLKcGWAFPTGC------SLNHcaahytPNTG 229
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490589630 206 DK-IIEKGDFVLIDYGAMYNGYISDTTRTFIVGGASEKQLEIynlVKEAQNVGVENmkAGVHATIPD--AEIRKVVKKYE 282
Cdd:PTZ00053 230 DKtVLTYDDVCKLDFGTHVNGRIIDCAFTVAFNPKYDPLLQA---TKDATNTGIKE--AGIDVRLSDigAAIQEVIESYE 304
|
|
| |
