NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|490657882|ref|WP_004522872|]
View 

RNA polymerase sigma factor RpoH [Burkholderia pseudomallei]

Protein Classification

RNA polymerase sigma factor RpoH( domain architecture ID 11482333)

RNA polymerase sigma factor RpoH is involved in regulating the expression of heat shock genes; sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released

Gene Ontology:  GO:0016987|GO:0003677|GO:0006352
PubMed:  3315851|3052291

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
25-311 0e+00

RNA polymerase factor sigma-32; Reviewed


:

Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 502.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  25 TLASHSMLPGHLGNIDAYIQAVNRIPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQE 104
Cdd:PRK06596   2 TKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 105 GNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHKKGTQAFTPEEIDGLAQEL 184
Cdd:PRK06596  82 GNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEEL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 185 NVKREEVAEMETRLSGGDIALEGQI-DDGEESYAPIAYLADSHNEPTAVLAARQRDMLQTDGIARALESLDARSRRIIEA 263
Cdd:PRK06596 162 GVSEEEVREMESRLSGQDASLDAPIdDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDIIEA 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 490657882 264 RWLNVDddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMRTALAAYA 311
Cdd:PRK06596 242 RWLDDD-----KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
25-311 0e+00

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 502.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  25 TLASHSMLPGHLGNIDAYIQAVNRIPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQE 104
Cdd:PRK06596   2 TKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 105 GNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHKKGTQAFTPEEIDGLAQEL 184
Cdd:PRK06596  82 GNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEEL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 185 NVKREEVAEMETRLSGGDIALEGQI-DDGEESYAPIAYLADSHNEPTAVLAARQRDMLQTDGIARALESLDARSRRIIEA 263
Cdd:PRK06596 162 GVSEEEVREMESRLSGQDASLDAPIdDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDIIEA 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 490657882 264 RWLNVDddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMRTALAAYA 311
Cdd:PRK06596 242 RWLDDD-----KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
37-309 6.90e-165

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 459.05  E-value: 6.90e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882   37 GNIDAYIQAVNRIPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRF 116
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRLREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  117 DPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHKKGTQA-FTPEEIDGLAQELNVKREEVAEME 195
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLQGwLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  196 TRLSGGDIALEGQIDDGEESY-APIAYLADSHNEPTAVLAARQRDMLQTDGIARALESLDARSRRIIEARWLNVDddgsg 274
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGgAPIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD----- 235
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 490657882  275 GSTLHDLAAEFGVSAERIRQIEASAMKKMRTALAA 309
Cdd:TIGR02392 236 KLTLQELAAEYGVSAERIRQIEKNAMKKLKAALAA 270
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
41-311 2.03e-108

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 315.84  E-value: 2.03e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  41 AYIQAVNRIPLLSAEEERQYATEYReQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQ 120
Cdd:COG0568    1 AYLREIGRVPLLTAEEEVELARRIQ-AGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPER 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 121 NVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQ-----RKLFFNLrSHKKGTQAfTPEEIdglAQELNVKREEVAEME 195
Cdd:COG0568   80 GFRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlnklRRAKRQL-LQELGREP-TPEEI---AEELGVPEEKVREML 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 196 tRLSGGDIALEGQIDDGEESyAPIAYLADSHNEPTAVLAARQrdmLQTDGIARALESLDARSRRIIEARWLNVDDDgsgG 275
Cdd:COG0568  155 -RLAREPVSLDAPVGDDEDS-ELGDLLEDEEAPSPEEALEEE---LLREELREALDTLTEREREILRLRFGLDDGE---P 226
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 490657882 276 STLHDLAAEFGVSAERIRQIEASAMKKMRTALAAYA 311
Cdd:COG0568  227 HTLEEIGKEFGVSRERVRQIEAKALRKLRHPLRSRK 262
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
76-145 1.37e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 78.40  E-value: 1.37e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882   76 LVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWR 145
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
246-304 1.93e-07

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 47.10  E-value: 1.93e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490657882 246 IARALESLDARSRRIIEARWLNvdddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGE-------GLSYEEIAEILGISRSTVRQRLHRALKKLR 55
 
Name Accession Description Interval E-value
PRK06596 PRK06596
RNA polymerase factor sigma-32; Reviewed
25-311 0e+00

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 235838 [Multi-domain]  Cd Length: 284  Bit Score: 502.40  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  25 TLASHSMLPGHLGNIDAYIQAVNRIPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQE 104
Cdd:PRK06596   2 TKALQLLALSPEGNLDAYIQAVNKIPMLTAEEEYMLAKRLREHGDLEAAKQLVLSHLRFVVHIARGYRGYGLPQADLIQE 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 105 GNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHKKGTQAFTPEEIDGLAQEL 184
Cdd:PRK06596  82 GNIGLMKAVKRFDPEVGVRLVSFAVHWIKAEIHEYILRNWRIVKVATTKAQRKLFFNLRKAKKRLGWLNPEEVEMVAEEL 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 185 NVKREEVAEMETRLSGGDIALEGQI-DDGEESYAPIAYLADSHNEPTAVLAARQRDMLQTDGIARALESLDARSRRIIEA 263
Cdd:PRK06596 162 GVSEEEVREMESRLSGQDASLDAPIdDDDEESGAPQDYLEDKSSDPADVLEEDNWEDQRRALLADALEGLDERSRDIIEA 241
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 490657882 264 RWLNVDddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMRTALAAYA 311
Cdd:PRK06596 242 RWLDDD-----KSTLQELAAEYGVSAERVRQIEKNAMKKLKAAIEAAA 284
rpoH_proteo TIGR02392
alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to ...
37-309 6.90e-165

alternative sigma factor RpoH; A sigma factor is a DNA-binding protein protein that binds to the DNA-directed RNA polymerase core to produce the holoenzyme capable of initiating transcription at specific sites. Different sigma factors act in vegetative growth, heat shock, extracytoplasmic functions (ECF), etc. This model represents the clade of sigma factors called RpoH and further restricted to the Proteobacteria. This protein may be called sigma-32, sigma factor H, heat shock sigma factor, and alternative sigma factor RpoH. Note that in some species the single locus rpoH may be replaced by two or more differentially regulated stress response sigma factors. [Cellular processes, Adaptations to atypical conditions, Transcription, Transcription factors]


Pssm-ID: 274107 [Multi-domain]  Cd Length: 270  Bit Score: 459.05  E-value: 6.90e-165
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882   37 GNIDAYIQAVNRIPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRF 116
Cdd:TIGR02392   1 GSLDAYIRAVNRIPMLTPEEEYQLAKRLREHGDLDAAKKLVLSHLRFVVKIARGYRGYGLPQADLIQEGNIGLMKAVKRF 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  117 DPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHKKGTQA-FTPEEIDGLAQELNVKREEVAEME 195
Cdd:TIGR02392  81 DPERGVRLVSFAVHWIKAEIHEYILRNWRLVKVATTKAQRKLFFNLRKMKKRLQGwLNPEEVEAIAEELGVSEREVREME 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  196 TRLSGGDIALEGQIDDGEESY-APIAYLADSHNEPTAVLAARQRDMLQTDGIARALESLDARSRRIIEARWLNVDddgsg 274
Cdd:TIGR02392 161 SRLSGQDMSLNASIDDDEDDGgAPIAYLVDKRSDPEDTLEEEQWEELQRQALANALGSLDARSRRIIEARWLDDD----- 235
                         250       260       270
                  ....*....|....*....|....*....|....*
gi 490657882  275 GSTLHDLAAEFGVSAERIRQIEASAMKKMRTALAA 309
Cdd:TIGR02392 236 KLTLQELAAEYGVSAERIRQIEKNAMKKLKAALAA 270
RpoD COG0568
DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA ...
41-311 2.03e-108

DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) [Transcription]; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440334 [Multi-domain]  Cd Length: 268  Bit Score: 315.84  E-value: 2.03e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  41 AYIQAVNRIPLLSAEEERQYATEYReQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQ 120
Cdd:COG0568    1 AYLREIGRVPLLTAEEEVELARRIQ-AGDEEAKRKLVEANLRLVVSIAKKYQGRGLPLLDLIQEGNLGLMKAVEKFDPER 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 121 NVRLVSYAIHWIKAEIHEYILRNWRMVKVATTKAQ-----RKLFFNLrSHKKGTQAfTPEEIdglAQELNVKREEVAEME 195
Cdd:COG0568   80 GFRFSTYATWWIRQAITRAIADQWRTIRLPVHMAEtlnklRRAKRQL-LQELGREP-TPEEI---AEELGVPEEKVREML 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 196 tRLSGGDIALEGQIDDGEESyAPIAYLADSHNEPTAVLAARQrdmLQTDGIARALESLDARSRRIIEARWLNVDDDgsgG 275
Cdd:COG0568  155 -RLAREPVSLDAPVGDDEDS-ELGDLLEDEEAPSPEEALEEE---LLREELREALDTLTEREREILRLRFGLDDGE---P 226
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 490657882 276 STLHDLAAEFGVSAERIRQIEASAMKKMRTALAAYA 311
Cdd:COG0568  227 HTLEEIGKEFGVSRERVRQIEAKALRKLRHPLRSRK 262
rpoH2 PRK07500
RNA polymerase factor sigma-32; Reviewed
50-309 1.22e-70

RNA polymerase factor sigma-32; Reviewed


Pssm-ID: 236033 [Multi-domain]  Cd Length: 289  Bit Score: 220.68  E-value: 1.22e-70
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  50 PLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAI 129
Cdd:PRK07500  19 PYLEREEEHALAYRWKDHRDEDALHRIISAHMRLVISMAGKFRRFGLPMNDLIQEGYVGLLEAAARFEPDREVRFSTYAT 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 130 HWIKAEIHEYILRNWRMVKVATTKAQRKLFFNLRSHK----KGTQAFTPEEIDG-LAQELNVKREEVAEMETRLSGGDIA 204
Cdd:PRK07500  99 WWIRASIQDYILRNWSIVRGGTSSAQKALFFNLRRLRarlaQADEELTKQEIHReIATALGVSLSDVEMMDARLSGPDAS 178
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 205 LEG-QIDDGEESYAPIAYLADSHNEP-----TAVLAARQRDMLQtdgiaRALESLDARSRRIIEARWLNVDddgsgGSTL 278
Cdd:PRK07500 179 LNApQSEEDEGRSERMDFLVDDSPLPdeqveSSIDGERRRRWLT-----QALQTLNERELRIIRERRLRED-----GATL 248
                        250       260       270
                 ....*....|....*....|....*....|.
gi 490657882 279 HDLAAEFGVSAERIRQIEASAMKKMRTALAA 309
Cdd:PRK07500 249 EALGEELGISKERVRQIEARALEKLRRALLS 279
PRK09210 PRK09210
RNA polymerase sigma factor RpoD; Validated
42-304 4.77e-36

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236413 [Multi-domain]  Cd Length: 367  Bit Score: 132.80  E-value: 4.77e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  42 YIQAVNRIPLLSAEEERQYATEYrEQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQN 121
Cdd:PRK09210 101 YLKEIGRVPLLTAEEEIELAKRI-EEGDEEAKQRLAEANLRLVVSIAKRYVGRGMLFLDLIQEGNMGLMKAVEKFDYRKG 179
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 122 VRLVSYAIHWIKAEIHEYILRNWRMVK-----VAT----TKAQRKLFFNLrshkkgTQAFTPEEIdglAQELNVKREEVA 192
Cdd:PRK09210 180 FKFSTYATWWIRQAITRAIADQARTIRipvhmVETinklIRVQRQLLQEL------GREPTPEEI---AEEMDMPPEKVR 250
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 193 EMeTRLSGGDIALEGQIddGEESyapiaylaDSH-------NEPTAVLAARQRDML--QTDGIaraLESLDARSRRIIEA 263
Cdd:PRK09210 251 EI-LKIAQEPVSLETPI--GEED--------DSHlgdfiedQDATSPADHAAYELLkeQLEDV---LDTLTDREENVLRL 316
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 490657882 264 RW-LnvdDDGSgGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK09210 317 RFgL---DDGR-TRTLEEVGKVFGVTRERIRQIEAKALRKLR 354
PRK05657 PRK05657
RNA polymerase sigma factor RpoS; Validated
47-308 3.72e-31

RNA polymerase sigma factor RpoS; Validated


Pssm-ID: 235548 [Multi-domain]  Cd Length: 325  Bit Score: 118.90  E-value: 3.72e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  47 NRI---PLLSAEEERQYATEYReQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVR 123
Cdd:PRK05657  60 NEIgysPLLTAEEEVYFARRAL-RGDFAARQRMIESNLRLVVKIAKRYLNRGLALLDLIEEGNLGLIRAVEKFDPERGFR 138
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 124 LVSYAIHWIKAEIHEYILRNWRMVKV---------ATTKAQRKLffnlrSHKKGTQAfTPEEIdglAQELNVKREEVAEM 194
Cdd:PRK05657 139 FSTYATWWIRQTIERAIMNQTRTIRLpvhvvkelnVYLRAAREL-----EHKLDHEP-SAEEI---AELLDKPVDDVSRM 209
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 195 ---ETRLSGGDIALEGqidDGEESYAPIayLADSHNEPTAVLAArQRDMLQTdgIARALESLDARSRRIIEARW-LNvdd 270
Cdd:PRK05657 210 lalNERITSLDTPLGG---DPEKSLLDI--LADEQENGPEDTTQ-DDDMKQS--IVKWLFELNDKQREVLARRFgLL--- 278
                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 490657882 271 dGSGGSTLHDLAAEFGVSAERIRQIEASAMKKMRTALA 308
Cdd:PRK05657 279 -GYEAATLEDVAREIGLTRERVRQIQVEALRRLREILQ 315
FliA COG1191
DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA ...
56-309 2.59e-30

DNA-directed RNA polymerase specialized sigma subunit [Transcription]; DNA-directed RNA polymerase specialized sigma subunit is part of the Pathway/BioSystem: RNA polymerase


Pssm-ID: 440804 [Multi-domain]  Cd Length: 236  Bit Score: 114.54  E-value: 2.59e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  56 EERQYATEYReQNNLDAARRLVLSHLRLVVSVARNYLG-YGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKA 134
Cdd:COG1191    1 DLEELLRRYQ-EGDEEAREELIEEYLPLVKKIASRLAGrLPAELDDLIQVGLIGLIEAIDRFDPSKGVSFETYAVPRIRG 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 135 EI------HEYILRNWRMVKVATTKAQRKLffnlrSHKKGtQAFTPEEIdglAQELNVKREEVAEMETRLSGGDIA-LEG 207
Cdd:COG1191   80 AIldylrdEDWVPRSVRELARKIEEAIEEL-----EQELG-REPTDEEI---AEELGISLEEVQEALEAANAYQLLsLDE 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 208 QIDDGEEsyapiayLADSHNEPTAVLAARQRDMLQTdgIARALESLDARSRRIIEARWLnvdddgsGGSTLHDLAAEFGV 287
Cdd:COG1191  151 PLEDGDD-------LLDLLESGDPEEELEHEELREA--LAEAIEQLPERERLVLSLYYF-------EELTLKEIAEVLGV 214
                        250       260
                 ....*....|....*....|..
gi 490657882 288 SAERIRQIEASAMKKMRTALAA 309
Cdd:COG1191  215 SESRVSRLHKKALARLREYLKE 236
PRK07921 PRK07921
RNA polymerase sigma factor SigB; Reviewed
52-311 2.96e-28

RNA polymerase sigma factor SigB; Reviewed


Pssm-ID: 181169 [Multi-domain]  Cd Length: 324  Bit Score: 110.98  E-value: 2.96e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  52 LSAEEERQYATEYREQNnldAARR-LVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIH 130
Cdd:PRK07921  69 LSEARKRDLAAVVRDGE---AARRhLLEANLRLVVSLAKRYTGRGMPLLDLIQEGNLGLIRAMEKFDYTKGFKFSTYATW 145
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 131 WIKAEIHEYILRNWRMV-----------KVATTKaqRKLFFNLrshkkGTQAfTPEEidgLAQELNVKREEVAEMeTRLS 199
Cdd:PRK07921 146 WIRQAITRGMADQSRTIrlpvhlveqvnKLARIK--RELHQQL-----GREA-TDEE---LAEESGIPEEKIADL-LEHS 213
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 200 GGDIALEGQIddGEESYAPIA-YLADShnEPTAVLAARQRDMLQTDgIARALESLDARSRRIIEARW-LnvdDDGSgGST 277
Cdd:PRK07921 214 RDPVSLDMPV--GSDEEAPLGdFIEDS--EATSAENAVIAGLLHTD-IRSVLATLDEREQQVIRLRFgL---DDGQ-PRT 284
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 490657882 278 LHDLAAEFGVSAERIRQIEASAMKKMRTA-----LAAYA 311
Cdd:PRK07921 285 LDQIGKLFGLSRERVRQIEREVMSKLRNGeradrLRSYA 323
PRK05901 PRK05901
RNA polymerase sigma factor; Provisional
38-304 5.68e-25

RNA polymerase sigma factor; Provisional


Pssm-ID: 235640 [Multi-domain]  Cd Length: 509  Bit Score: 104.31  E-value: 5.68e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  38 NIDAYIQAVNRIPLLSAEEERQ---------YATEYREQN-NLDAARR----------------LVLSHLRLVVSVARNY 91
Cdd:PRK05901 212 PVKAYLKQIGKVKLLNAEEEVElakrieaglYAEELLAEGeKLDPELRrdlqwigrdgkraknhLLEANLRLVVSLAKRY 291
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  92 LGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEI---------------HeyilrnwrMVKVAT--TKA 154
Cdd:PRK05901 292 TNRGLSFLDLIQEGNLGLIKAVEKFDYTKGYKFSTYATWWIRQAItramadqartiripvH--------MVETINklGRI 363
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 155 QRKLffnlrshkkgTQAF----TPEEidgLAQELNVKREEVAEMEtRLSGGDIALEGQI-DDGEESYAPiaYLADSHNEp 229
Cdd:PRK05901 364 EREL----------LQELgrepTPEE---LAKEMGFTPEKVREIQ-KYNREPISLDKTIgKEGDSQFGD--FIEDSEAV- 426
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 490657882 230 TAVLAARQRdMLQtDGIARALESLDARSRRIIEARWlNVDDDGSggSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK05901 427 SPVDAVSFT-LLQ-DQLQEVLETLSEREAGVIRMRF-GLTDGQP--KTLDEIGQVYGVTRERIRQIESKTLRKLR 496
PRK07406 PRK07406
RNA polymerase sigma factor RpoD; Validated
39-304 2.75e-23

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 236012 [Multi-domain]  Cd Length: 373  Bit Score: 98.32  E-value: 2.75e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  39 IDAYIQAVNRIPLLSAEEE----RQYAT-----EYREQNNLD------------------------------AARRLVLS 79
Cdd:PRK07406  65 IRVYLQEIGRIRLLRPDEEielaRKIADlleleELREQFESElgrepsdkewaelvdmplpkfrrrlmlgrrAKEKMVQS 144
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  80 HLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVATtkaqrKLF 159
Cdd:PRK07406 145 NLRLVVSIAKKYMNRGLSFQDLIQEGSLGLIRAAEKFDHEKGYKFSTYATWWIRQAITRAIADQSRTIRLPV-----HLY 219
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 160 FNLRSHKKGTQAftpeeidgLAQELNVK--REEVAE-ME---------TRLSGGDIALEGQIDDGEESYAPIAYLADSHN 227
Cdd:PRK07406 220 ETISRIKKTTKV--------LSQEFGRKptEEEIAEsMEmtieklrfiAKSAQLPISLETPIGKEEDSRLGDFIEADGET 291
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490657882 228 EPTAVlaarQRDMLQTDgIARALESLDARSRRIIEARWlNVDDDGSggSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK07406 292 PEDDV----AKNLLRED-LEGVLATLSPRERDVLRLRY-GLDDGRM--KTLEEIGQIFNVTRERIRQIEAKALRKLR 360
PRK07598 PRK07598
RNA polymerase sigma factor SigC; Validated
70-304 1.71e-22

RNA polymerase sigma factor SigC; Validated


Pssm-ID: 236067 [Multi-domain]  Cd Length: 415  Bit Score: 96.48  E-value: 1.71e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  70 LDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVK- 148
Cdd:PRK07598 174 LRAKEHMIKANLRLVVSVAKKYQNRGLELLDLVQEGTLGLERAVEKFDPTKGYRFSTYAYWWIRQGITRAIATQSRTIRl 253
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 149 -VATT-------KAQRKLffnlrSHKKGTqafTPeEIDGLAQELNVKREEVAEMETRLSgGDIALEGQI-DDGEESYAPI 219
Cdd:PRK07598 254 pVHITeklnkikKAQRKI-----SQEKGR---TP-TIEDIAQELEMTPTQVREVLLRVP-RSVSLETKVgKDKDTELGDL 323
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 220 AYLADSHNEPTAVLAARQRDMLQTdgiaraLESLDARSRRIIEARWlnvdddGSGGSTLHDLaAEFG----VSAERIRQI 295
Cdd:PRK07598 324 LETDDISPEEMLMRESLQRDLQHL------LADLTSRERDVIRMRF------GLADGHTYSL-AEIGraldLSRERVRQI 390

                 ....*....
gi 490657882 296 EASAMKKMR 304
Cdd:PRK07598 391 ESKALQKLR 399
PRK08215 PRK08215
RNA polymerase sporulation sigma factor SigG;
43-304 9.70e-20

RNA polymerase sporulation sigma factor SigG;


Pssm-ID: 181296 [Multi-domain]  Cd Length: 258  Bit Score: 86.54  E-value: 9.70e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  43 IQAVN--RIPLLSAEEERQYATEYReQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQ 120
Cdd:PRK08215   8 ICGVNtsKLPVLKNEEMRELFERMQ-NGDKEAREKLINGNLRLVLSVIQRFNNRGENVDDLFQVGCIGLMKAIDNFDLSQ 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 121 NVRLVSYAIHWIKAEIHEYiLRNWRMVKVATT---KAQRKLFFNLRSHKKGTQAFTPEEIdglAQELNVKREEVAEmetr 197
Cdd:PRK08215  87 NVKFSTYAVPMIIGEIRRY-LRDNNPIRVSRSlrdIAYKALQVREKLINENSKEPTVEEI---AKELEVPREEVVF---- 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 198 lsggdiALEGqIDDGEESYAPI-------AYLADShneptaVLAARQRDMLQTDGIA--RALESLDARSRRIIEARWLNv 268
Cdd:PRK08215 159 ------ALDA-IQDPVSLFEPIyhdggdpIYVMDQ------ISDEKNKDENWLEEIAlkEAMKKLNDREKLILNLRFFQ- 224
                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 490657882 269 dddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK08215 225 ------GKTQMEVAEEIGISQAQVSRLEKAALKHMR 254
PRK07405 PRK07405
RNA polymerase sigma factor SigD; Validated
41-304 2.75e-19

RNA polymerase sigma factor SigD; Validated


Pssm-ID: 180963 [Multi-domain]  Cd Length: 317  Bit Score: 86.35  E-value: 2.75e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  41 AYIQAVNRIPLLSAEEERQYA--------------------------TEYREQNNLD-------------AARRLVLSHL 81
Cdd:PRK07405  12 TYLREIGRVPLLTHEEEILYGkqvqrlvalqeireelaeelgreptdAEWAKAAKLSeeelrsaiaegeaAKRKMVEANL 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  82 RLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKV---------ATT 152
Cdd:PRK07405  92 RLVVSVAKKYLKRNVDLLDLIQEGTIGMQRGVEKFDPTKGYRFSTYAYWWIRQAITRAIAEKSRTIRLpihiteklnKIK 171
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 153 KAQRKLffnlrSHKKGTQAFTPEeidgLAQELNVKREEVAEMETRlSGGDIALEGQIDDGEESYAPiAYLADSHNEPT-- 230
Cdd:PRK07405 172 KAQRQL-----SQQLGRAATIGE----LAEELELTPKQVREYLER-ARQPLSLDLRVGDNQDTELG-ELLEDTGASPEdf 240
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490657882 231 AVLAARQRDmlqtdgIARALESLDARSRRIIEARWLNVDDDgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK07405 241 ATQSSLQLD------LERLMEDLTPQQKEVIALRFGLEDGQ---PLTLAKIGERLNISRERVRQIEREALSKLR 305
Sigma70_r2 pfam04542
Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. ...
76-145 1.37e-18

Sigma-70 region 2; Region 2 of sigma-70 is the most conserved region of the entire protein. All members of this class of sigma-factor contain region 2. The high conservation is due to region 2 containing both the -10 promoter recognition helix and the primary core RNA polymerase binding determinant. The core binding helix, interacts with the clamp domain of the largest polymerase subunit, beta prime. The aromatic residues of the recognition helix, found at the C-terminus of this domain are though to mediate strand separation, thereby allowing transcription initiation.


Pssm-ID: 427998 [Multi-domain]  Cd Length: 71  Bit Score: 78.40  E-value: 1.37e-18
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882   76 LVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWR 145
Cdd:pfam04542   1 LVERYLPLVYSLARRYLGDGADAEDLVQEGFLGLWRAIERFDPERGVSFSTWLYTIIRNAIIDYLRKQRR 70
PRK05658 PRK05658
RNA polymerase sigma factor RpoD; Validated
72-304 2.87e-17

RNA polymerase sigma factor RpoD; Validated


Pssm-ID: 235549 [Multi-domain]  Cd Length: 619  Bit Score: 82.15  E-value: 2.87e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  72 AARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEI--------------- 136
Cdd:PRK05658 381 AKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAItrsiadqartiripv 460
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 137 H--EYIlrNwRMVKVattkaQRKLFfnlrsHKKGTQAfTPEEidgLAQEL-----------NVKREEvaemetrlsggdI 203
Cdd:PRK05658 461 HmiETI--N-KLNRI-----SRQML-----QEIGREP-TPEE---LAERLgmpedkvrkvlKIAKEP------------I 511
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 204 ALEGQIDDGEesyapiaylaDSH-----NEPTAVL---AARQRDMLQTdgIARALESLDARSRRIIEARWlnvdddGSGG 275
Cdd:PRK05658 512 SLETPIGDDE----------DSHlgdfiEDKNAELpidAAIQESLREA--TTDVLASLTPREAKVLRMRF------GIDM 573
                        250       260       270
                 ....*....|....*....|....*....|..
gi 490657882 276 STLHDL---AAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK05658 574 NTDHTLeevGKQFDVTRERIRQIEAKALRKLR 605
PRK05949 PRK05949
RNA polymerase sigma factor; Validated
42-304 3.77e-17

RNA polymerase sigma factor; Validated


Pssm-ID: 180321 [Multi-domain]  Cd Length: 327  Bit Score: 80.27  E-value: 3.77e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  42 YIQAVNRIPLLSAEEERQY--------------------------ATEYREQNNLD-------------AARRLVLSHLR 82
Cdd:PRK05949  23 YLHEIGRVPLLTHEQEIVYgkqvqqmmslleakealakklgrepsLPEWAEAVNLSetelkqtlkqgkrAKQKMIEANLR 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  83 LVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKV---------ATTK 153
Cdd:PRK05949 103 LVVAIAKKYQKRNMEFLDLIQEGTLGLERGVEKFDPTRGYKFSTYAYWWIRQAITRAIAQQARTIRLpihiteklnKIKK 182
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 154 AQRKLffnlrSHKKGTQAfTPEEIdglAQELNVKREEVAEMETrLSGGDIALEGQIDDGEESYAPiAYLADSHNEPTAVL 233
Cdd:PRK05949 183 TQREL-----SQKLGRSA-TPAEI---AKELELEPSQIREYLS-MARQPISLDVRVGDNQDTELS-ELLEDEGPSPDQYI 251
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 490657882 234 AarqRDMLQTDgIARALESLDARSRRIIEARW-LNvddDGSGGStLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK05949 252 T---QELLRQD-LNNLLAELTPQQREVLTLRFgLE---DGKELS-LAKVGERLNLSRERVRQLEHQALAHLR 315
PRK05572 PRK05572
RNA polymerase sporulation sigma factor, SigF/SigG family;
71-309 5.51e-16

RNA polymerase sporulation sigma factor, SigF/SigG family;


Pssm-ID: 180137 [Multi-domain]  Cd Length: 252  Bit Score: 76.16  E-value: 5.51e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  71 DAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYiLRNWRMVKVA 150
Cdd:PRK05572  32 EARDTLVEKNLRLVWSVVQRFLNRGYEPDDLFQIGCIGLLKAVDKFDLSYDVKFSTYAVPMIIGEIQRF-LRDDGTVKVS 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 151 -----TTKAQRKLFFNLRshKKGTQAFTPEEIdglAQELNVKREEVAeMETRLSGGDIALEGQI--DDGeesyAPIaYLA 223
Cdd:PRK05572 111 rslkeTANKIRKDKDELS--KELGREPTIEEL---AEYLGVTPEEVV-LAQEASRSPQSIHETVheNDG----DPI-TLL 179
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 224 DSHNEPTavlaarQRDMLqtDGIA--RALESLDARSRRIIEARWLNvdddgsgGSTLHDLAAEFGVSAERIRQIEASAMK 301
Cdd:PRK05572 180 DQIADQS------EEDWF--DKIAlkEAIRELDERERLIVYLRYFK-------DKTQSEVAKRLGISQVQVSRLEKKILK 244

                 ....*...
gi 490657882 302 KMRTALAA 309
Cdd:PRK05572 245 QMKEKLDE 252
PRK08583 PRK08583
RNA polymerase sigma factor SigB; Validated
52-307 4.21e-13

RNA polymerase sigma factor SigB; Validated


Pssm-ID: 236306 [Multi-domain]  Cd Length: 257  Bit Score: 67.80  E-value: 4.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  52 LSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHW 131
Cdd:PRK08583  10 LTKEEVNKWIAEYQENQDEEAQEKLVKHYKNLVESLAYKYSKGQSHHEDLVQVGMVGLLGAIRRYDPSFGRSFEAFAVPT 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 132 IKAEIHEYIL-RNW-----RMVKVATTKAqrklffnlrshKKGTQAFTPE-----EIDGLAQELNVKREEVAE-METRLS 199
Cdd:PRK08583  90 IIGEIKRYLRdKTWsvhvpRRIKELGPKI-----------KKAVDELTTElqrspKISEIADRLGVSEEEVLEaMEMGKS 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 200 ---------------GGDIAL---EGQIDDGEESyapiayladshneptavlaARQRDMLQtdgiaRALESLDARSRRII 261
Cdd:PRK08583 159 yqalsvdhsieadsdGSTVTLldiVGQQEDGYEL-------------------TEQRMILE-----KILPVLSDREKSII 214
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 490657882 262 EARWLnvdDDGSGGSTLHDLaaefGVSAERIRQIEASAMKKMRTAL 307
Cdd:PRK08583 215 QCTFI---ENLSQKETGERL----GISQMHVSRLQRQAIKKLREAA 253
PRK05803 PRK05803
RNA polymerase sporulation sigma factor SigK;
52-303 1.43e-12

RNA polymerase sporulation sigma factor SigK;


Pssm-ID: 180266 [Multi-domain]  Cd Length: 233  Bit Score: 66.12  E-value: 1.43e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  52 LSAEEERQYATEYREqNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHW 131
Cdd:PRK05803  31 LSEEEERKYLELMKE-GDEEARNILIERNLRLVAHIVKKFENTGEDVDDLISIGTIGLIKAIESFDAGKGTKLATYAARC 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 132 IKAEIheyilrnwrmvkvattkaqrklFFNLRSHKKgtqaftpeeidglaqelnvkreevaemeTRlsgGDIALEGQID- 210
Cdd:PRK05803 110 IENEI----------------------LMHLRNLKK----------------------------TK---KEVSLQDPIGv 136
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 211 --DGEEsyapIAYLADSHNEPTAVLAARQRDMlQTDGIARALESLDARSRRIIEARW-LnvddDGSGGSTLHDLAAEFGV 287
Cdd:PRK05803 137 dkEGNE----ISLIDILGSEEDDVIEQVELKM-EVEKLYKKIDILDEREKEVIEMRYgL----GNGKEKTQREIAKALGI 207
                        250
                 ....*....|....*.
gi 490657882 288 SAERIRQIEASAMKKM 303
Cdd:PRK05803 208 SRSYVSRIEKRALKKL 223
PRK06288 PRK06288
RNA polymerase sigma factor WhiG; Reviewed
49-308 1.46e-12

RNA polymerase sigma factor WhiG; Reviewed


Pssm-ID: 235770 [Multi-domain]  Cd Length: 268  Bit Score: 66.63  E-value: 1.46e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  49 IPLLSAEEERQYATEYREQNNLDAARRLVLSHLRLVVSVArNYLGYGLP----HGDLIQEGNIGLMKAVKRFDPAQNVRL 124
Cdd:PRK06288   9 IPKYAQQDETELWREYKKTGDPKIREYLILKYSPLVKYVA-GRIAVGMPqnveFDDLVSYGVFGLIDAIEKFDPEREIKF 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 125 VSYAIHWIKAEIH------EYILRNWRMVKVATTKAQRKLFFNLRshkkgtQAFTPEEIdglAQELNVKREEVAEMETRL 198
Cdd:PRK06288  88 KTYAVTRIRGAIFdelrsiDWIPRSVRQKARQIERAIAMLEARLG------RTPSDEEI---ADELGISLEEYNSLLSKL 158
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 199 SGGD-IALEGQIDDGEESYAPiaYLADSHNEPTA---VLAARQRDMLQTdgIARALESLDARSRRIIEARWLNvdddgsg 274
Cdd:PRK06288 159 SGTSvVSLNDLWFGGDEGDEV--SLMDTLESPAAlnpDEIAEREEIKRV--IVEAIKTLPEREKKVLILYYYE------- 227
                        250       260       270
                 ....*....|....*....|....*....|....
gi 490657882 275 GSTLHDLAAEFGVSAERIRQIEASAMKKMRTALA 308
Cdd:PRK06288 228 DLTLKEIGKVLGVTESRISQLHTKAVLQLRAKLA 261
sigma70-ECF TIGR02937
RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the ...
71-307 3.39e-12

RNA polymerase sigma factor, sigma-70 family; This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.


Pssm-ID: 274357 [Multi-domain]  Cd Length: 158  Bit Score: 63.52  E-value: 3.39e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882   71 DAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRlvSYAIHWIKAEIHEYIlrnwrmvkva 150
Cdd:TIGR02937   1 EAFEELYERYLPLVYRYARRYLGDDADAEDLVQEAFLKLLEALDRFDPEGSFK--AWLFRIARNLILDYL---------- 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  151 ttkaqrklffnlrSHKKGTQAFTPEEIDGLAQELNVKREEVAEMETRLsggdialegqiddgeesyapiayladshnept 230
Cdd:TIGR02937  69 -------------RRKRRLRRELDLLEELLDSDPSPEEELEQEEEREA-------------------------------- 103
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490657882  231 avlaarqrdmlqtdgIARALESLDARSRRIIEARWLNvdddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMRTAL 307
Cdd:TIGR02937 104 ---------------LREALEKLPEREREVLVLRYLE-------GLSYKEIAEILGISVGTVKRRLKRARKKLRELL 158
PRK07122 PRK07122
RNA polymerase sigma factor SigF; Reviewed
75-308 3.14e-11

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 168831 [Multi-domain]  Cd Length: 264  Bit Score: 62.49  E-value: 3.14e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  75 RLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRNWRMVKVAttKA 154
Cdd:PRK07122  44 RIVTRCLPLADHIARRFDGRGEPRDDLVQVARVGLVNAVNRFDVETGSDFVSFAVPTIMGEVRRHFRDNSWSVKVP--RR 121
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 155 QRKLFFNL-RSHKKGTQ----AFTPEEidgLAQELNVKREEVAEMetrLSGGD----IALEGQIDDGEESYAPIA-YLAD 224
Cdd:PRK07122 122 LKELHLRLgRATAELSQrlgrAPTASE---LAAELGMDREEVVEG---LVAGSayntLSIDSGGGSGDDDARAIAdTLGD 195
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 225 shnEPTAVLAARQRDMLQTdgiarALESLDARSRRIIEARWLnvdddgsGGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:PRK07122 196 ---VDAGLDQIENREALRP-----LLAALPERERTVLVLRFF-------ESMTQTQIAERVGISQMHVSRLLAKTLARLR 260

                 ....
gi 490657882 305 TALA 308
Cdd:PRK07122 261 DQLE 264
PRK08301 PRK08301
RNA polymerase sporulation sigma factor SigE;
50-143 3.91e-11

RNA polymerase sporulation sigma factor SigE;


Pssm-ID: 236228 [Multi-domain]  Cd Length: 234  Bit Score: 61.80  E-value: 3.91e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  50 PLLSAEEErQYATEYREQNNLDAARRLVLSHLRLVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAI 129
Cdd:PRK08301  32 PPLSKEEE-EYLLNKLPKGDEAVRSLLIERNLRLVVYIARKFENTGINIEDLISIGTIGLIKAVNTFNPEKKIKLATYAS 110
                         90
                 ....*....|....
gi 490657882 130 HWIKAEIHEYILRN 143
Cdd:PRK08301 111 RCIENEILMYLRRN 124
PRK05911 PRK05911
RNA polymerase sigma factor sigma-28; Reviewed
64-310 4.42e-11

RNA polymerase sigma factor sigma-28; Reviewed


Pssm-ID: 235644 [Multi-domain]  Cd Length: 257  Bit Score: 61.94  E-value: 4.42e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  64 YREQNNLDAARRLVLSHLRLVVSVARNyLGYGLPHG----DLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEY 139
Cdd:PRK05911  16 YWSTQEIEYRDVLIEFYLPLVKNVAHR-LISGMPSHvkteDLYASGVEGLVRAVERFDPEKSRRFEGYALFLIKAAIIDD 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 140 iLRNWRMVKVATTKAQRKLFFNLRSHKkgtQAFTPEEIDG-LAQELNVKREEVAE-METRLSGGDIALEGQ---IDDGEE 214
Cdd:PRK05911  95 -LRKQDWVPRSVHQKANKLADAMDSLR---QSLGKEPTDGeLCEYLNISQQELSGwFSSARPALILSLNEEfpcQSDDEA 170
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 215 SYAPIAYLADSHNEpTAVLAARQRDMLQTdgIARALESLDARSRRIIEARWLNvdddgsgGSTLHDLAAEFGVSAERIRQ 294
Cdd:PRK05911 171 GLALEERIADERAE-TGYDVVDKKEFSSI--LAEAILALEEKERKVMALYYYE-------ELVLKEIGKILGVSESRVSQ 240
                        250
                 ....*....|....*.
gi 490657882 295 IEASAMKKMRTALAAY 310
Cdd:PRK05911 241 IHSKALLKLRATLSAF 256
PRK07408 PRK07408
RNA polymerase sigma factor SigF; Reviewed
75-289 1.53e-10

RNA polymerase sigma factor SigF; Reviewed


Pssm-ID: 180965 [Multi-domain]  Cd Length: 256  Bit Score: 60.32  E-value: 1.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  75 RLVLSHLRLVVSVARNYLGY-GLPHGDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEY---------ILRNW 144
Cdd:PRK07408  29 QLVELNLGLVRKEAHRWSNQcSEPYEDLVQVGSLGLIRAIERFDPSKGHAFSSFAIPYIRGEIQHYlrdksptvrIPRRW 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 145 RMVKVATTKAQRKLffnlrSHKKGTQAfTPEEIdglAQELNVKREEVAEME------TRLSggdiaLEGQIDDGEESYAP 218
Cdd:PRK07408 109 QELQRQAKKVRQEL-----RQELGRQP-TDQEI---AQALDISLEEWQEIKlalqnrTPLS-----LDAPVNQDEDGSTS 174
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 490657882 219 IA-YLADSHnepTAVLAARQRDMLQtdgIARALESLDARSRRIIEARWlnvdddgsggstLHDL----AAE-FGVSA 289
Cdd:PRK07408 175 LGdLLPDPR---YRSFQLAQEDRIR---LQQALAQLEERTREVLEFVF------------LHDLtqkeAAErLGISP 233
fliA PRK06986
flagellar biosynthesis sigma factor; Validated
74-311 8.80e-10

flagellar biosynthesis sigma factor; Validated


Pssm-ID: 235901 [Multi-domain]  Cd Length: 236  Bit Score: 57.94  E-value: 8.80e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  74 RRLVLsHL--RLVVSVARNylgyglphgDLIQEGNIGLMKAVKRFDPAQNVRLVSYAIHWIKAEIHEYILRN-W------ 144
Cdd:PRK06986  22 KRIAL-RLkaRLPASVDLD---------DLIQAGMIGLLEAARRYDGEQGASFETYAGQRIRGAMLDELRSLdWvprsvr 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 145 ---RMVKVATTKAQRKLffnlrshkkGTQAfTPEEIdglAQELNVKREEVAEMETRLSGGDIAlegQIDD--GEESYAPI 219
Cdd:PRK06986  92 rnaREVAQAIRQLEQEL---------GREP-TDTEV---AEKLGLSLEEYREMLLDTNISQLF---SIDElrGEHGDSIL 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 220 AYLADSHNEPTAVLAarqRDMLQtDGIARALESLDARSRRII-----EArwLNvdddgsggstLHDLAAEFGVSAERIRQ 294
Cdd:PRK06986 156 VTEDHQDEDPLQQLE---DEELR-EALVEAIESLPEREQLVLslyyqEE--LN----------LKEIGAVLGVSESRVSQ 219
                        250
                 ....*....|....*..
gi 490657882 295 IEASAMKKMRTALAAYA 311
Cdd:PRK06986 220 IHSQAIKRLRARLGEWT 236
Sigma70_r4 pfam04545
Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 ...
249-304 5.57e-09

Sigma-70, region 4; Region 4 of sigma-70 like sigma-factors are involved in binding to the -35 promoter element via a helix-turn-helix motif. Due to the way Pfam works, the threshold has been set artificially high to prevent overlaps with other helix-turn-helix families. Therefore there are many false negatives.


Pssm-ID: 461347 [Multi-domain]  Cd Length: 50  Bit Score: 51.27  E-value: 5.57e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 490657882  249 ALESLDARSRRIIEARWLnvdddgsGGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:pfam04545   1 ALASLPPRERQVLVLRYG-------EGLTLEEIGERLGISRERVRQIEKRALRKLR 49
Sigma70_r4 cd06171
Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in ...
246-304 1.93e-07

Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or plastid core RNA polymerase to specific promoter elements located upstream of transcription initiation points. The SR4 of Ec sigma70 and other essential primary SFs contact promoter sequences located 35 base-pairs upstream of the initiation point, recognizing a 6-base-pair -35 consensus TTGACA. Sigma70 related SFs also include SFs which are dispensable for bacterial cell growth for example Ec sigmaS, SFs which activate regulons in response to a specific signal for example heat-shock Ec sigmaH, and a group of SFs which includes the extracytoplasmic function (ECF) SFs and is typified by Ec sigmaE which contains SR2 and -4 only. ECF SFs direct the transcription of genes that regulate various responses including periplasmic stress and pathogenesis. Ec sigmaE SR4 also contacts the -35 element, but recognizes a different consensus (a 7-base-pair GGAACTT). Plant SFs recognize sigma70 type promoters and direct transcription of the major plastid RNA polymerase, plastid-encoded RNA polymerase (PEP).


Pssm-ID: 100119 [Multi-domain]  Cd Length: 55  Bit Score: 47.10  E-value: 1.93e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 490657882 246 IARALESLDARSRRIIEARWLNvdddgsgGSTLHDLAAEFGVSAERIRQIEASAMKKMR 304
Cdd:cd06171    4 LEEALDKLPEREREVILLRFGE-------GLSYEEIAEILGISRSTVRQRLHRALKKLR 55
PRK08295 PRK08295
RNA polymerase sporulation sigma factor SigH;
83-118 7.03e-05

RNA polymerase sporulation sigma factor SigH;


Pssm-ID: 181361 [Multi-domain]  Cd Length: 208  Bit Score: 42.97  E-value: 7.03e-05
                         10        20        30
                 ....*....|....*....|....*....|....*.
gi 490657882  83 LVVSVARNYLGYGLPHGDLIQEGNIGLMKAVKRFDP 118
Cdd:PRK08295  36 FVRAKARSYFLIGADREDIVQEGMIGLYKAIRDYDK 71
Sigma70_r1_2 pfam00140
Sigma-70 factor, region 1.2;
39-66 4.68e-04

Sigma-70 factor, region 1.2;


Pssm-ID: 425482 [Multi-domain]  Cd Length: 34  Bit Score: 36.91  E-value: 4.68e-04
                          10        20
                  ....*....|....*....|....*...
gi 490657882   39 IDAYIQAVNRIPLLSAEEERQYATEYRE 66
Cdd:pfam00140   3 VRLYLKEIGRIPLLTAEEEVELAKRIEA 30
PRK07670 PRK07670
FliA/WhiG family RNA polymerase sigma factor;
55-307 4.84e-04

FliA/WhiG family RNA polymerase sigma factor;


Pssm-ID: 181075 [Multi-domain]  Cd Length: 251  Bit Score: 40.80  E-value: 4.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882  55 EEERQYATEYREQNNLDAARRLVLSHLRLV-VSVARnyLGYGLPHG----DLIQEGNIGLMKAVKRFDPAQNVRLVSYAI 129
Cdd:PRK07670   6 YEEQKLWDRWKEERDPDAADELIRRYMPLVhYHVQR--ISVGLPKSvskdDLKSLGMLGLYDALEKFDPSRDLKFDTYAS 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 130 HWIKAEI------HEYILRNWR----MVKVATTKAQRKLffnLRShkkgtqaFTPEEIdglAQELNVKREEV-AEMETRL 198
Cdd:PRK07670  84 FRIRGAIidglrkEDWLPRSMRektkKVEAAIEKLEQRY---MRN-------VTPKEV---AAELGMTEEEVeATMNEGF 150
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490657882 199 SGGDIALEGQIDDGEESYAPIAYLADSHNEP--TAVLAARQRDMLqtdgiARALESLDARSRRIIEarwLNVDDDgsggS 276
Cdd:PRK07670 151 FANLLSIDEKTHDQDDGENVSVTIRDDKTPTpeEKLLKEELIEEL-----AEKIKQLSEKEQLVIS---LFYKEE----L 218
                        250       260       270
                 ....*....|....*....|....*....|.
gi 490657882 277 TLHDLAAEFGVSAERIRQIEASAMKKMRTAL 307
Cdd:PRK07670 219 TLTEIGQVLNLSTSRISQIHSKALFKLKKLL 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH