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Conserved domains on  [gi|490726295|ref|WP_004588802|]
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MULTISPECIES: copper resistance CopC family protein [Gammaproteobacteria]

Protein Classification

copper resistance protein CopC( domain architecture ID 10006414)

copper resistance protein CopC is a periplasmic protein that functions in copper resistance

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
CopC COG2372
Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];
7-115 1.43e-29

Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];


:

Pssm-ID: 441939  Cd Length: 125  Bit Score: 103.50  E-value: 1.43e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   7 AVAILGLVLTFSASAHISLKQSIPAQEAMLMQGPEELSLIFSGEVR--LAKVIIKDEKNKTINFDfKPSATPSTDFNWSL 84
Cdd:COG2372   13 LALLLLLLAAAPASAHAVLVSSSPADGATVTAAPTEVTLTFSEPVEpgFSTVTVTDPDGERVDVG-DPTVDGAKTLTVPL 91
                         90       100       110
                 ....*....|....*....|....*....|..
gi 490726295  85 PS-LAQGTYTVKWTALGGDGHKMTGTFRFMVH 115
Cdd:COG2372   92 PApLPPGTYTVSWRVVSADGHPVSGSFTFTVG 123
 
Name Accession Description Interval E-value
CopC COG2372
Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];
7-115 1.43e-29

Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];


Pssm-ID: 441939  Cd Length: 125  Bit Score: 103.50  E-value: 1.43e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   7 AVAILGLVLTFSASAHISLKQSIPAQEAMLMQGPEELSLIFSGEVR--LAKVIIKDEKNKTINFDfKPSATPSTDFNWSL 84
Cdd:COG2372   13 LALLLLLLAAAPASAHAVLVSSSPADGATVTAAPTEVTLTFSEPVEpgFSTVTVTDPDGERVDVG-DPTVDGAKTLTVPL 91
                         90       100       110
                 ....*....|....*....|....*....|..
gi 490726295  85 PS-LAQGTYTVKWTALGGDGHKMTGTFRFMVH 115
Cdd:COG2372   92 PApLPPGTYTVSWRVVSADGHPVSGSFTFTVG 123
CopC pfam04234
CopC domain; CopC is a bacterial blue copper protein that binds 1 atom of copper per protein ...
22-112 4.53e-21

CopC domain; CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.


Pssm-ID: 427806  Cd Length: 92  Bit Score: 80.80  E-value: 4.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   22 HISLKQSIPAQEAMLMQGPEELSLIFSGEVRL--AKVIIKDEKNKTInFDFKPSATPSTDFNWSLPSLAQGTYTVKWTAL 99
Cdd:pfam04234   1 HAALVSSTPADGATVAAAPAEVTLTFSEPVEPafSSVTVTDPDGVGA-PDTVDGATDGATLTVPLPPLPAGTYTVAWRVV 79
                          90
                  ....*....|...
gi 490726295  100 GGDGHKMTGTFRF 112
Cdd:pfam04234  80 SADGHPVSGSFTF 92
copper_CopC NF033814
copper homeostasis periplasmic binding protein CopC;
12-114 3.21e-14

copper homeostasis periplasmic binding protein CopC;


Pssm-ID: 468192  Cd Length: 109  Bit Score: 63.73  E-value: 3.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295  12 GLVLTFSASAHISLKQSIPAQEAmLMQGPEELSLIFSGEV--RLAKVIIKDEKNktinfdfkPSATPSTDFNWSLPS--- 86
Cdd:NF033814   1 SLLAAGAALAHAHLKSSTPAANA-TVAAPAKITLTFSEGLepAFSGVKLTMTGM--------PGPMVVTGAAVLGGEdgk 71
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 490726295  87 ---------LAQGTYTVKWTALGGDGHKMTGTFRFMV 114
Cdd:NF033814  72 tlvvplaqpLAAGTYTVDWHVVSVDGHKTTGSYSFTV 108
PRK10301 PRK10301
CopC domain-containing protein YobA;
7-114 1.18e-06

CopC domain-containing protein YobA;


Pssm-ID: 182365  Cd Length: 124  Bit Score: 44.51  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   7 AVAILGLVLTFSAS-AHISLKQSIPAQEAMLMQGPEELSLIFSG--EVRLAKVIIKDEKNKTINFdfKPSATPSTDFNWS 83
Cdd:PRK10301  11 ALAILTTSLVTPAVwAHAHLTHQYPAANAQVTAAPQALTLNFSEgiEPGFSGATITGPKQENIKT--LPAKRNEQDQKQL 88
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490726295  84 LPSLAQ----GTYTVKWTALGGDGHKMTGTFRFMV 114
Cdd:PRK10301  89 IVPLADslkpGTYTVDWHVVSVDGHKTKGHYTFSV 123
 
Name Accession Description Interval E-value
CopC COG2372
Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];
7-115 1.43e-29

Copper-binding protein CopC (methionine-rich) [Inorganic ion transport and metabolism];


Pssm-ID: 441939  Cd Length: 125  Bit Score: 103.50  E-value: 1.43e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   7 AVAILGLVLTFSASAHISLKQSIPAQEAMLMQGPEELSLIFSGEVR--LAKVIIKDEKNKTINFDfKPSATPSTDFNWSL 84
Cdd:COG2372   13 LALLLLLLAAAPASAHAVLVSSSPADGATVTAAPTEVTLTFSEPVEpgFSTVTVTDPDGERVDVG-DPTVDGAKTLTVPL 91
                         90       100       110
                 ....*....|....*....|....*....|..
gi 490726295  85 PS-LAQGTYTVKWTALGGDGHKMTGTFRFMVH 115
Cdd:COG2372   92 PApLPPGTYTVSWRVVSADGHPVSGSFTFTVG 123
CopC pfam04234
CopC domain; CopC is a bacterial blue copper protein that binds 1 atom of copper per protein ...
22-112 4.53e-21

CopC domain; CopC is a bacterial blue copper protein that binds 1 atom of copper per protein molecule. Along with CopA, CopC mediates copper resistance by sequestration of copper in the periplasm.


Pssm-ID: 427806  Cd Length: 92  Bit Score: 80.80  E-value: 4.53e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   22 HISLKQSIPAQEAMLMQGPEELSLIFSGEVRL--AKVIIKDEKNKTInFDFKPSATPSTDFNWSLPSLAQGTYTVKWTAL 99
Cdd:pfam04234   1 HAALVSSTPADGATVAAAPAEVTLTFSEPVEPafSSVTVTDPDGVGA-PDTVDGATDGATLTVPLPPLPAGTYTVAWRVV 79
                          90
                  ....*....|...
gi 490726295  100 GGDGHKMTGTFRF 112
Cdd:pfam04234  80 SADGHPVSGSFTF 92
copper_CopC NF033814
copper homeostasis periplasmic binding protein CopC;
12-114 3.21e-14

copper homeostasis periplasmic binding protein CopC;


Pssm-ID: 468192  Cd Length: 109  Bit Score: 63.73  E-value: 3.21e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295  12 GLVLTFSASAHISLKQSIPAQEAmLMQGPEELSLIFSGEV--RLAKVIIKDEKNktinfdfkPSATPSTDFNWSLPS--- 86
Cdd:NF033814   1 SLLAAGAALAHAHLKSSTPAANA-TVAAPAKITLTFSEGLepAFSGVKLTMTGM--------PGPMVVTGAAVLGGEdgk 71
                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 490726295  87 ---------LAQGTYTVKWTALGGDGHKMTGTFRFMV 114
Cdd:NF033814  72 tlvvplaqpLAAGTYTVDWHVVSVDGHKTTGSYSFTV 108
PRK10301 PRK10301
CopC domain-containing protein YobA;
7-114 1.18e-06

CopC domain-containing protein YobA;


Pssm-ID: 182365  Cd Length: 124  Bit Score: 44.51  E-value: 1.18e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490726295   7 AVAILGLVLTFSAS-AHISLKQSIPAQEAMLMQGPEELSLIFSG--EVRLAKVIIKDEKNKTINFdfKPSATPSTDFNWS 83
Cdd:PRK10301  11 ALAILTTSLVTPAVwAHAHLTHQYPAANAQVTAAPQALTLNFSEgiEPGFSGATITGPKQENIKT--LPAKRNEQDQKQL 88
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 490726295  84 LPSLAQ----GTYTVKWTALGGDGHKMTGTFRFMV 114
Cdd:PRK10301  89 IVPLADslkpGTYTVDWHVVSVDGHKTKGHYTFSV 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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