|
Name |
Accession |
Description |
Interval |
E-value |
| PFK |
pfam00365 |
Phosphofructokinase; |
2-278 |
1.23e-66 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 210.27 E-value: 1.23e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLASA---DITLFNGGIPGLLDKNHHEVAWRDLVDfsIASIP--IITSGRTSRRLLRS 76
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYrghEVYGIRNGYEGLVEGDIDELTWRDVSG--ILNRGgtILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 77 EYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRA 155
Cdd:pfam00365 79 GREKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 156 LpGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKLTQQNSVVILCSEGYtreyspgfqGAIDTM 235
Cdd:pfam00365 159 H-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA---------SDGEFL 228
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 490994151 236 IKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVR 278
Cdd:pfam00365 229 AKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-325 |
1.07e-58 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 192.21 E-value: 1.07e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASA-DITL--FNGGIPGLLDknhhevawRDLVDFSIASI-PIITSG----RTSRR 72
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKyGIEVygIRDGYEGLLE--------GDIIDLTREDVsGILQRGgtilGSSRS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 73 LL---RSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSR 148
Cdd:COG0205 74 KPfktEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 149 LRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKL-TQQNSVVILCSEGYTREY--- 224
Cdd:COG0205 154 LRDTAAS-HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRkRGKGYSIIVVAEGAGDEDgea 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 225 ----------SPGFQGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKAI-IINS 293
Cdd:COG0205 233 vleadtdafgHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVgIRRG 312
|
330 340 350
....*....|....*....|....*....|..
gi 490994151 294 SNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:COG0205 313 EIVLVPLEEVANKEKPVDPDSPLIQLARELGI 344
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-325 |
5.11e-49 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 166.41 E-value: 5.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASA-DITLFngGIP----GLLDknhhevawRDLVDFSIASI-PIITSG----RTS 70
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISeGLEVY--GIYdgyaGLLE--------GDIVKLDLKSVsDIINRGgtilGSA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 71 RR---LLRSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVS 147
Cdd:PRK03202 72 RFpefKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAID 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 148 RLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKH-KLTQQNSVVILCSEGYtreysp 226
Cdd:PRK03202 152 RLRDTASS-HERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKgRERGKKHAIIVVAEGV------ 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 227 gfqGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKAIIInSSNKPIPIDL---V 303
Cdd:PRK03202 225 ---MPAEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGI-QNNKIVHVPIeeaV 300
|
330 340
....*....|....*....|..
gi 490994151 304 SMKKRLVDTEghHYKLAKQLNI 325
Cdd:PRK03202 301 ENMKHPFDKD--LYELAKKLSI 320
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-322 |
2.31e-43 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 152.07 E-value: 2.31e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLA---SADITLFNGGIPGLLDKNHHEVAWRDLVDFSIASIPIITSGRTSRRLLRSEY 78
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAiaeGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 79 ETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNT 152
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEewpskyQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 153 GRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPL---ETLAERV-KHKLTQQNSVVILCSEGYTReyspgF 228
Cdd:cd00363 162 ASS-HQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADeweEEMVDVIkKRRERGKRHGIVIVAEGAID-----F 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 229 QGAIDT---MIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVR-----------CIQSGMKNKAIiinss 294
Cdd:cd00363 236 IPKPITeklLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVElllegtggtpvGIQNLNENQVV----- 310
|
330 340
....*....|....*....|....*....
gi 490994151 295 NKPIpIDLVSMKKRL-VDTEGHHYKLAKQ 322
Cdd:cd00363 311 RHPL-TEAVNMTKRVgVDLEGRPFKKFAK 338
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
1-281 |
2.01e-26 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 109.74 E-value: 2.01e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASAD-ITLF--NGGIPGLLDKNHHEVAWRDLVDFSIASIPIITsgrTSRRLLRSE 77
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARgHTVIaiHNGFSGLARHDVRELTWSDVEGWVGEGGSELG---TNRSLPGDD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 78 YETIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-------EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:TIGR02478 467 LGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDaarekypAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKLTQQNSVV----ILCSEGYTREYSP 226
Cdd:TIGR02478 547 QSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRagklILRNEKASKVYTT 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 490994151 227 GFqgaIDTMIKQlEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMAsevVRCIQ 281
Cdd:TIGR02478 627 DF---IARIISE-EGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLA---IRAVD 674
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PFK |
pfam00365 |
Phosphofructokinase; |
2-278 |
1.23e-66 |
|
Phosphofructokinase;
Pssm-ID: 459783 [Multi-domain] Cd Length: 271 Bit Score: 210.27 E-value: 1.23e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLASA---DITLFNGGIPGLLDKNHHEVAWRDLVDfsIASIP--IITSGRTSRRLLRS 76
Cdd:pfam00365 1 RIGILTSGGDAPGMNAAIRAVVRTAIYrghEVYGIRNGYEGLVEGDIDELTWRDVSG--ILNRGgtILGTSRSKPFKTEE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 77 EYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGRA 155
Cdd:pfam00365 79 GREKIAENLKKLGIDALVVIGGDGSLTGANKLSeERGIPVVGIPKTIDNDIPGTDYTIGFDTALNTIVEAIDRIRDTASS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 156 LpGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKLTQQNSVVILCSEGYtreyspgfqGAIDTM 235
Cdd:pfam00365 159 H-NRVFVVEVMGRHCGWLALMAGLAGGADAILIPEIPFDIEELCEKIKELRKGKRFSIIVVAEGA---------SDGEFL 228
|
250 260 270 280
....*....|....*....|....*....|....*....|...
gi 490994151 236 IKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVR 278
Cdd:pfam00365 229 AKLIEEGTGIETRVTVLGHVQRGGTPSAFDRILATRLGVKAVE 271
|
|
| PfkA |
COG0205 |
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part ... |
1-325 |
1.07e-58 |
|
6-phosphofructokinase [Carbohydrate transport and metabolism]; 6-phosphofructokinase is part of the Pathway/BioSystem: Glycolysis
Pssm-ID: 439975 [Multi-domain] Cd Length: 344 Bit Score: 192.21 E-value: 1.07e-58
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASA-DITL--FNGGIPGLLDknhhevawRDLVDFSIASI-PIITSG----RTSRR 72
Cdd:COG0205 2 KRIGILTSGGDAPGLNAAIRAVVRTAIKyGIEVygIRDGYEGLLE--------GDIIDLTREDVsGILQRGgtilGSSRS 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 73 LL---RSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSR 148
Cdd:COG0205 74 KPfktEEGREKALENLKKLGIDALVVIGGDGSLDGAAKLAEEyGIPVVGIPKTIDNDLPGTDYTIGFDTAVNTAAEAIDR 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 149 LRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKL-TQQNSVVILCSEGYTREY--- 224
Cdd:COG0205 154 LRDTAAS-HERVFVVEVMGRHAGWLALAAGLAGGADLILIPEVPFDLDKLLEKLKERRkRGKGYSIIVVAEGAGDEDgea 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 225 ----------SPGFQGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKAI-IINS 293
Cdd:COG0205 233 vleadtdafgHVRLGGIGEYLAKEIEERTGIETRVTVLGHLQRGGSPSAFDRVLASRLGAAAVELLLEGKTGVMVgIRRG 312
|
330 340 350
....*....|....*....|....*....|..
gi 490994151 294 SNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:COG0205 313 EIVLVPLEEVANKEKPVDPDSPLIQLARELGI 344
|
|
| PRK03202 |
PRK03202 |
ATP-dependent 6-phosphofructokinase; |
1-325 |
5.11e-49 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235111 [Multi-domain] Cd Length: 320 Bit Score: 166.41 E-value: 5.11e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASA-DITLFngGIP----GLLDknhhevawRDLVDFSIASI-PIITSG----RTS 70
Cdd:PRK03202 2 KRIGVLTSGGDAPGMNAAIRAVVRTAISeGLEVY--GIYdgyaGLLE--------GDIVKLDLKSVsDIINRGgtilGSA 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 71 RR---LLRSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVS 147
Cdd:PRK03202 72 RFpefKDEEGRAKAIENLKKLGIDALVVIGGDGSYMGAKRLTEHGIPVIGLPGTIDNDIAGTDYTIGFDTALNTAVEAID 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 148 RLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKH-KLTQQNSVVILCSEGYtreysp 226
Cdd:PRK03202 152 RLRDTASS-HERVFIVEVMGRHAGDLALHAGIAGGAEVILIPEVPFDIEELCAKIKKgRERGKKHAIIVVAEGV------ 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 227 gfqGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKAIIInSSNKPIPIDL---V 303
Cdd:PRK03202 225 ---MPAEELAKEIEERTGLETRVTVLGHIQRGGSPTAFDRVLASRMGAHAVELLLEGKGGRMVGI-QNNKIVHVPIeeaV 300
|
330 340
....*....|....*....|..
gi 490994151 304 SMKKRLVDTEghHYKLAKQLNI 325
Cdd:PRK03202 301 ENMKHPFDKD--LYELAKKLSI 320
|
|
| PFK |
cd00363 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-322 |
2.31e-43 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to PFK family that includes ATP- and pyrophosphate (PPi)- dependent phosphofructokinases. Some members evolved by gene duplication and thus have a large C-terminal/N-terminal extension comprising a second PFK domain. Generally, ATP-PFKs are allosteric homotetramers, and PPi-PFKs are dimeric and nonallosteric except for plant PPi-PFKs which are allosteric heterotetramers.
Pssm-ID: 238216 [Multi-domain] Cd Length: 338 Bit Score: 152.07 E-value: 2.31e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLA---SADITLFNGGIPGLLDKNHHEVAWRDLVDFSIASIPIITSGRTSRRLLRSEY 78
Cdd:cd00363 2 KIGVLTSGGDAPGMNAAIRGVVRSAiaeGLEVYGIYEGYAGLVEGDIKELDWESVSDIINRGGTIIGSARCKEFRTEEGR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 79 ETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNT 152
Cdd:cd00363 82 AKAAENLKKHGIDALVVIGGDGSYTGADLLTEewpskyQGFNVIGLPGTIDNDIKGTDYTIGFDTALKTIVEAIDRIRDT 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 153 GRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPL---ETLAERV-KHKLTQQNSVVILCSEGYTReyspgF 228
Cdd:cd00363 162 ASS-HQRTFVVEVMGRHCGDIALEAGLATGADIIFIPEEPAADeweEEMVDVIkKRRERGKRHGIVIVAEGAID-----F 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 229 QGAIDT---MIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVR-----------CIQSGMKNKAIiinss 294
Cdd:cd00363 236 IPKPITeklLAKLVEERLGFDTRATVLGHVQRGGTPTAFDRILASRLGAEAVElllegtggtpvGIQNLNENQVV----- 310
|
330 340
....*....|....*....|....*....
gi 490994151 295 NKPIpIDLVSMKKRL-VDTEGHHYKLAKQ 322
Cdd:cd00363 311 RHPL-TEAVNMTKRVgVDLEGRPFKKFAK 338
|
|
| Bacterial_PFK |
cd00763 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-324 |
9.02e-40 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include bacterial ATP-dependent phosphofructokinases. These are allosrterically regulated homotetramers; the subunits are of about 320 amino acids.
Pssm-ID: 238388 [Multi-domain] Cd Length: 317 Bit Score: 142.16 E-value: 9.02e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLASA---DITLFNGGIPGLLDKNHHEVAWRDLVDfsiasipIITSGRT---SRRLLR 75
Cdd:cd00763 2 RIGVLTSGGDAPGMNAAIRGVVRSAIAeglEVYGIRDGYAGLIAGDIVPLDRYSVSD-------IINRGGTflgSARFPE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 76 SEYETIAKK----IKSLRIDVLIMAGGDGSLQFLNTLSEFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRN 151
Cdd:cd00763 75 FKDEEGQAKaieqLKKHGIDALVVIGGDGSYMGAMRLTEHGFPCVGLPGTIDNDIPGTDYTIGFDTALNTVVEAIDRIRD 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 152 TGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKH-KLTQQNSVVILCSEGYTreyspgfqg 230
Cdd:cd00763 155 TSSS-HQRISVVEVMGRHCGDIALAAGIAGGAEFIVIPEAEFDREEVANRIKAgIERGKKHAIVVVAEGVY--------- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 231 AIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKAIIINSS---NKPIpIDLVSMKK 307
Cdd:cd00763 225 DVDELAKEIEEATGFETRATVLGHIQRGGSPTAFDRILASRMGAYAVELLLAGKGGLAVGIQNEqlvHHDI-IDAIENMK 303
|
330
....*....|....*..
gi 490994151 308 RLvdtEGHHYKLAKQLN 324
Cdd:cd00763 304 PF---KKDWLALAKKLS 317
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
1-281 |
2.01e-26 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 109.74 E-value: 2.01e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASAD-ITLF--NGGIPGLLDKNHHEVAWRDLVDFSIASIPIITsgrTSRRLLRSE 77
Cdd:TIGR02478 390 LRIAIIHVGAPAGGMNAATRSAVRYALARgHTVIaiHNGFSGLARHDVRELTWSDVEGWVGEGGSELG---TNRSLPGDD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 78 YETIAKKIKSLRIDVLIMAGGDGSLQFLNTLS-------EFDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:TIGR02478 467 LGTIAYYFQQHKIDGLIIIGGFEAFEALYQLDaarekypAFRIPMVVIPATISNNVPGTEYSLGSDTALNEITEYCDNIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKLTQQNSVV----ILCSEGYTREYSP 226
Cdd:TIGR02478 547 QSASASKRRVFVVETMGGYSGYLATMAGLATGADAAYIPEEGISLKDLQEDIEHLKETFAEGRagklILRNEKASKVYTT 626
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 490994151 227 GFqgaIDTMIKQlEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMAsevVRCIQ 281
Cdd:TIGR02478 627 DF---IARIISE-EGKGRFDARTAVLGHMQQGGSPSPFDRVRATRLA---IRAVD 674
|
|
| 6PF1K_euk |
TIGR02478 |
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one ... |
2-303 |
1.60e-25 |
|
6-phosphofructokinase, eukaryotic type; Members of this family are eukaryotic (with one exception) ATP-dependent 6-phosphofructokinases (EC 2.7.1.11) in which two tandem copies of the phosphofructokinase are found. Members are found, often including several isozymes, in animals and fungi and in the bacterium Propionibacterium acnes KPA171202 (a human skin commensal).
Pssm-ID: 274152 [Multi-domain] Cd Length: 746 Bit Score: 107.04 E-value: 1.60e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLA---SADITLFNGGIPGLLD--KNHHEVAWRDLVdfSIASI--PIITSGRTSRRLL 74
Cdd:TIGR02478 2 RIAVLTSGGDAQGMNAAVRAVVRMAiyvGCRVYAIREGYQGLVDggDNIEEAQWEDVR--GILSLggTIIGTARCKEFRE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 75 RSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE-------------------------FDIncfgVGM--TIDNDVY 127
Cdd:TIGR02478 80 RPGRLKAARNLVSNGIDALVVIGGDGSLTGADLFREewpslleelvdtgkitaeqaeehrhLTI----VGLvgSIDNDMC 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 128 GSDYTIGFSTACEQIIKEVSRLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQmPLETLAERVKHKLT 207
Cdd:TIGR02478 156 GTDMTIGADSALHRICEAIDAISSTAQS-HQRAFVVEVMGRHCGYLALMAAIATGADYVFIPERP-PEEGWEDQLCHKLK 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 208 ------QQNSVVILCsegytreyspgfQGAIDT--------MIKQ-LEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIM 272
Cdd:TIGR02478 234 rnrkagKRKTIVIVA------------EGAIDRdlnpitseDVKDvLVERLGLDTRITVLGHVQRGGAPSAFDRILATRQ 301
|
330 340 350
....*....|....*....|....*....|...
gi 490994151 273 ASEVVRCIQSGMKNK--AIIINSSNKPIPIDLV 303
Cdd:TIGR02478 302 GVEAVLAVLESTPETpsPVISLRGNKIVRKPLV 334
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-285 |
3.86e-24 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 102.98 E-value: 3.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLASAD---ITLFNGGIPGLLDKNHHEVAWRDLVDFSIASIPIITsgrTSRRLLRSE 77
Cdd:cd00764 390 LNIAIVNVGAPAAGMNAAVRSAVRYGLAHghrPYAIYDGFEGLAKGQIVELGWIDVGGWTGRGGSELG---TKRTLPKKD 466
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 78 YETIAKKIKSLRIDVLIMAGG----DGSLQFLNTLSEFDINCFGVGM---TIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:cd00764 467 LETIAYNFQKYGIDGLIIVGGfeayKGLLQLREAREQYEEFCIPMVLipaTVSNNVPGTDFSLGSDTALNALMKYCDRIK 546
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKH-----KLTQQNSVV---ILCSEGYTR 222
Cdd:cd00764 547 QSASGTKRRVFIVETMGGYCGYLATMTGLAVGADAAYVFEEPFNIRDLQENVEHltekmKTTIGRGLVlrnEKCNENYTT 626
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 490994151 223 EYSPgfqgaidtmikQLEPQIGVRI---RKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMK 285
Cdd:cd00764 627 VFTY-----------ELYSEEGKGVfdcRTNVLGHVQQGGAPSPFDRNFGTKFAVKAMKWIEQKLK 681
|
|
| PRK14071 |
PRK14071 |
ATP-dependent 6-phosphofructokinase; |
2-325 |
1.20e-21 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 184487 [Multi-domain] Cd Length: 360 Bit Score: 93.98 E-value: 1.20e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLASA----DITLFNGGIPGLLDKNHHEVAW-RDLVDfsiasiPIITSGRT------- 69
Cdd:PRK14071 6 RIGILTSGGDCAGLNAVIRAVVHRARGtygwEVIGIRDATQGLMARPPQYIELdLDQVD------DLLRMGGTilgttnk 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 70 --------SRRLLRSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF-DINCFGVGMTIDNDVYGSDYTIGFSTACE 140
Cdd:PRK14071 80 gdpfafpmPDGSLRDRSQEIIDGYHSLGLDALIGIGGDGSLAILRRLAQQgGINLVGIPKTIDNDVGATEVSIGFDTAVN 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 141 QIIKEVSRLRNTGrALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQMPLETLAERVKHKLTQ-QNSVVILCSEG 219
Cdd:PRK14071 160 IATEALDRLHFTA-ASHNRVMILEVMGRDAGHIALAAGIAGGADVILIPEIPYTLENVCKKIRERQEEgKNFCLVVVSEA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 220 --------YTREYSPG---FQGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASEVVRCIQSGMKNKA 288
Cdd:PRK14071 239 vrteegeqVTKTQALGedrYGGIGQYLAEQIAERTGAETRVTVLGHIQRGGIPSPRDRLLASAFGVAAVDLIAQGKFDRM 318
|
330 340 350
....*....|....*....|....*....|....*...
gi 490994151 289 III-NSSNKPIPIDLVSMKKRLVDTEGHHYKLAKQLNI 325
Cdd:PRK14071 319 VAWqNRQVVSVPIAEAIATYRAVDPEGTLVKTARGLGI 356
|
|
| Eukaryotic_PFK |
cd00764 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
2-280 |
2.15e-20 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include eukaryotic ATP-dependent phosphofructokinases. These have evolved from the bacterial PFKs by gene duplication and fusion events and exhibit complex allosteric behavior.
Pssm-ID: 238389 [Multi-domain] Cd Length: 762 Bit Score: 91.81 E-value: 2.15e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLA---SADITLFNGGIPGLLDKNHH--EVAWRDLVDFSIASIPIITSGRTSRRLLRS 76
Cdd:cd00764 5 AIAVLTSGGDAQGMNAAVRAVVRMGiyvGAKVFFVYEGYEGLVKGGDYikQAEWESVSNWLQEGGTIIGSARCKEFRERE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 77 EYETIAKKIKSLRIDVLIMAGGDGSLQFLNTL-SEF----------------------DINCFGVGMTIDNDVYGSDYTI 133
Cdd:cd00764 85 GRLQAAYNLIQRGITNLCVIGGDGSLTGADLFrSEWpslleelvkdgkiteeevakyqHLNIVGMVGSIDNDFCGTDMTI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 134 GFSTACEQIIKEVSRLRNTGRAlPGRVFMVEILGGYCGELTLQSAIKSNADIALIPESQmPLETLAERVKHKLTQ----- 208
Cdd:cd00764 165 GTDSALHRICEVVDAITTTAQS-HQRTFVLEVMGRHCGYLALVSGLATGADWIFIPERP-PEDGWEDQMCRRLSEhrsrg 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 209 -QNSVVILCsegytreyspgfQGAIDtmiKQLEP------------QIGVRIRKTIVGYGLRNGDPTCEEIYQGTIMASE 275
Cdd:cd00764 243 kRLNIIIVA------------EGAID---DQLKPitsedvkdlvveRLGLDTRVTTLGHVQRGGTPSAFDRILASLMGVE 307
|
....*
gi 490994151 276 VVRCI 280
Cdd:cd00764 308 AVMAL 312
|
|
| PTZ00286 |
PTZ00286 |
6-phospho-1-fructokinase; Provisional |
2-262 |
9.64e-18 |
|
6-phospho-1-fructokinase; Provisional
Pssm-ID: 185539 Cd Length: 459 Bit Score: 83.55 E-value: 9.64e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLASAD-----ITLFNGGIPGLLDKNHHEVAWRDLVDFSIASIPIITSGRTSRRLlrs 76
Cdd:PTZ00286 89 KAGIVTCGGLCPGLNVVIRELVMNLINNygvktIYGAKYGYKGLYKEDWIKLDPKDVKTIHRLGGTILGSSRGGFDP--- 165
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 77 eyETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLR 150
Cdd:PTZ00286 166 --KVMVDTLIRHGINILFTLGGDGTHRGALAIYKelrrrkLNISVVGIPKTIDNDIPIIDESFGFQTAVEEAQNAIRAAY 243
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 151 NTGRALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPLETLAERVKHKLTQQNSVVILCSEGYTREYSPG-F 228
Cdd:PTZ00286 244 VEAKSAKNGVGIVKLMGRDSGFIALHASVASaDVNVCLIPEFDIPLEGVLEYIEQRLQKKGHCVIVVAEGAGQSLKDAdL 323
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 490994151 229 QGAIDTMIKQLEPQIGVRIRKTIVGYGLRNG--------DPT 262
Cdd:PTZ00286 324 DLGTDASGNKKLWDIGVYLKDEITKYLKKKKpehtvkyiDPS 365
|
|
| PTZ00287 |
PTZ00287 |
6-phosphofructokinase; Provisional |
1-238 |
1.75e-11 |
|
6-phosphofructokinase; Provisional
Pssm-ID: 240345 [Multi-domain] Cd Length: 1419 Bit Score: 65.06 E-value: 1.75e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIARLA-----SADITLFNGGIPGLLDKNHHEVA------WRDLVDFSiasipIITSGRT 69
Cdd:PTZ00287 178 LKIGIILSGGPAPGGHNVISGIYDYAkryneQSQVIGFLGGIDGLYSKNYVTITdslmnrFRNLGGFN-----MLWSGRG 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 70 SRRlLRSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTACE- 140
Cdd:PTZ00287 253 KVR-NKDDLIAIENIVAKLKLNGLVIIGGDGSNSNAALISEYfaerqiPISIIGIPKTIDGDLKSEaiEISFGFDTATKt 331
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 141 --QIIKEVSRLRNTGRALpgrVFMVEILGGYCGELTLQSAIKSNADIALIPES----QMPLETLAERV-----KHKLTQQ 209
Cdd:PTZ00287 332 ysEVIGNLCTDVKTGHNV---YHVVRVMGRSASHVVLECALQTRPNIVLIGEEvekeNLSLKDIVSNIvntilKRRSLNK 408
|
250 260 270
....*....|....*....|....*....|..
gi 490994151 210 NSVVILCSEGYTrEYSPGFQ---GAIDTMIKQ 238
Cdd:PTZ00287 409 NYGVILIPEGLI-EFVPEMKiliGELNVILKE 439
|
|
| PRK14072 |
PRK14072 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; |
75-219 |
5.29e-11 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase;
Pssm-ID: 237600 [Multi-domain] Cd Length: 416 Bit Score: 62.96 E-value: 5.29e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 75 RSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGSDYTIGFSTACEQI---IKE 145
Cdd:PRK14072 89 RAEYERLLEVFKAHDIGYFFYNGGNDSMDTALKVSQLakkmgyPIRCIGIPKTIDNDLPGTDHCPGFGSAAKYIatsVLE 168
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 146 VSrLRNtgRALPG--RVFMVEILGGYCGELTLQSAIKSN-----ADIALIPESQMPLETLAERVKHKLTQQNSVVILCSE 218
Cdd:PRK14072 169 AA-LDV--AAMANtsKVFILEVMGRHAGWLAAAAALAKQnpddaPHLIYLPERPFDEEKFLADVRAIVKRYGYCVVVVSE 245
|
.
gi 490994151 219 G 219
Cdd:PRK14072 246 G 246
|
|
| PLN02884 |
PLN02884 |
6-phosphofructokinase |
1-261 |
5.69e-11 |
|
6-phosphofructokinase
Pssm-ID: 178472 [Multi-domain] Cd Length: 411 Bit Score: 62.91 E-value: 5.69e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQIArlasadITLFNGGIPGLLDKNHhevAWRDLVDFSIASIP--------IITSGRTSRR 72
Cdd:PLN02884 54 VKAAIVTCGGLCPGLNDVIRQIV------FTLEIYGVKNIVGIPF---GYRGFFEKGLSEMPlsrkvvqnIHLSGGSLLG 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 73 LLRSEYET--IAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIK 144
Cdd:PLN02884 125 VSRGGAKTsdIVDSIEARGINMLFVLGGNGTHAGANAIHNecrkrkMKVSVVGVPKTIDNDILLMDKTFGFDTAVEEAQR 204
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 145 EVSRLRNTGRALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPL---ETLAERVKHKLTQQNSVVILCSEGY 220
Cdd:PLN02884 205 AINSAYIEAHSAYHGIGLVKLMGRSSGFIAMHASLASgQVDICLIPEVPFTLdgpNGVLRHLEHLIETKGSAVVCVAEGA 284
|
250 260 270 280
....*....|....*....|....*....|....*....|.
gi 490994151 221 TREYSPGfQGAIDTMIKQLEPQIGVRIRKTIVGYGLRNGDP 261
Cdd:PLN02884 285 GQDLLQK-TNATDASGNPVLGDIGVHLQQEIKKHFKDIGVP 324
|
|
| PRK07085 |
PRK07085 |
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional |
1-240 |
1.29e-09 |
|
diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional
Pssm-ID: 235930 Cd Length: 555 Bit Score: 59.16 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFI---FQIARLASADITLFN--GGIPGLLDKNHHEVAwRDLVDF--SIASIPIITSGRTSrrl 73
Cdd:PRK07085 71 LKVGVILSGGQAPGGHNVIaglFDGLKKLNPDSKLFGfiGGPLGLLNGKYIEIT-EEVIDEyrNTGGFDMIGSGRTK--- 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 74 LRSE--YETIAKKIKSLRIDVLIMAGGDGSlqflNT----LSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTAC 139
Cdd:PRK07085 147 IETEeqKEACLETVKKLKLDGLVIIGGDDS----NTnaaiLAEYfakhgcKTQVIGVPKTIDGDLKNEfiETSFGFDTAT 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 140 E---QIIKEVSRLRNTGRALpgrVFMVEILGGYCGELTLQSAIKSNADIALIPE----SQMPLETLAER-----VKHKLT 207
Cdd:PRK07085 223 KtysEMIGNISRDALSAKKY---WHFIKLMGRSASHIALECALQTHPNICLISEevaeKKMSLQDIVHYiasviADRAAK 299
|
250 260 270
....*....|....*....|....*....|...
gi 490994151 208 QQNSVVILCSEGYTrEYSPgfqgAIDTMIKQLE 240
Cdd:PRK07085 300 GKNYGVILIPEGLI-EFIP----EMKSLIKELN 327
|
|
| Pyrophosphate_PFK |
cd00765 |
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of ... |
1-222 |
2.11e-09 |
|
Phosphofructokinase, a key regulatory enzyme in glycolysis, catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-biphosphate. The members belong to a subfamily of the PFKA family (cd00363) and include pyrophosphate-dependent phosphofructokinases. These are found in bacteria as well as plants. These may be dimeric nonallosteric enzymes as in bacteria or allosteric heterotetramers as in plants.
Pssm-ID: 238390 Cd Length: 550 Bit Score: 58.34 E-value: 2.11e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFI---FQIARLASADITL--FNGGIPGLLDKNHHEV------AWRDLVDFSiasipIITSGRT 69
Cdd:cd00765 73 LKIGIVLSGGQAPGGHNVIsglFDYLKERAKGSTLygFKGGPAGILKCDYIELnaeyiqPYRNTGGFD-----MICSGRT 147
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 70 SRRlLRSEYETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGSDYTI--GFSTACEQ 141
Cdd:cd00765 148 KIE-TEDQFKQAEETAKKLDLDALVVIGGDDSNTNAALLAENfrskglKTRVIGVPKTIDGDLKNKEIETsfGFDTATKI 226
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 142 IIKEVSRLRNTGRALPGRVFMVEILGGYCGELTLQSAIKSNADIALIPEsqmplETLAErvkhKLTQQNSVVILCSEGYT 221
Cdd:cd00765 227 YSELIGNVMRDARSTGKYWHFVKLMGRSASHIALECALKTHPNICIISE-----EVSAQ----KQTLKNITDYMVDVICK 297
|
.
gi 490994151 222 R 222
Cdd:cd00765 298 R 298
|
|
| PRK06830 |
PRK06830 |
ATP-dependent 6-phosphofructokinase; |
2-254 |
3.88e-09 |
|
ATP-dependent 6-phosphofructokinase;
Pssm-ID: 235869 Cd Length: 443 Bit Score: 57.57 E-value: 3.88e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARLAS-----ADITLFNGGIPGLLDKNHHEVAwrDLVDFSIASI-----PIITSGRTSR 71
Cdd:PRK06830 82 KAAIVTCGGLCPGLNDVIRAIVLELHhhygvRRILGIRYGYQGLIPRYGHDPV--ELTPEVVADIhefggTILGSSRGPQ 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 72 RLlrseyETIAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKE 145
Cdd:PRK06830 160 DP-----EEIVDTLERMNINILFVIGGDGTLRGASAIAEeierrgLKISVIGIPKTIDNDINFIQKSFGFETAVEKATEA 234
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 146 VSRLRNTGRALPGRVFMVEILGGYCGELTLQSAI-KSNADIALIPESQMPLET---LAERVKHKLTQQNSVVILCSEGYT 221
Cdd:PRK06830 235 IRCAHVEANGAPNGIGLVKLMGRHSGFIAAYAALaSKDVNFVLIPEVPFDLEGpngLLAALEKRLAERGHAVIVVAEGAG 314
|
250 260 270
....*....|....*....|....*....|...
gi 490994151 222 REYSPGFQGAIDTMIKQLEpQIGVRIRKTIVGY 254
Cdd:PRK06830 315 QELFDDTGETDASGNPKLG-DIGLFLKDRIKEY 346
|
|
| PTZ00468 |
PTZ00468 |
phosphofructokinase family protein; Provisional |
2-239 |
3.64e-07 |
|
phosphofructokinase family protein; Provisional
Pssm-ID: 185647 [Multi-domain] Cd Length: 1328 Bit Score: 51.90 E-value: 3.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 2 KIGMVISGGDVSGINNFIFQIARL-----ASADITLFNGGIPGLLDKNHHEVAWRDLVDF-SIASIPIITSGR---TSRR 72
Cdd:PTZ00468 104 RIGVVLSGGQASGGHNVIAGLMSYiklcnQSSQLFGFLGGPEGVYSERYRELTEDDINGIlNQGGFNIICSGRhkiETEE 183
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 73 LLRSEYETIAKkiksLRIDVLIMAGGDGSLQFLNTLSEF------DINCFGVGMTIDNDVYGS--DYTIGFSTA----CE 140
Cdd:PTZ00468 184 QMRASLEICEK----LKLHGLVVIGGDDSNTNAAVLAEYfkrnssSTVVVGCPKTIDGDLKNEviETSFGYDTAvktySE 259
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 141 QIIKEVSRLRNTGRalpgRVFMVEILGGYCGELTLQSAIKSNADIAL----IPESQMPLETLAERVKHKLTQQNSV---- 212
Cdd:PTZ00468 260 QIGSIMDAIKTEGY----GYYFVRLMGRSASHITLECGLQTRANMILigeeIKEENRSLMSIVDEIVEMILKRDSLgkkh 335
|
250 260
....*....|....*....|....*...
gi 490994151 213 -VILCSEGYTrEYSPGFQgaidTMIKQL 239
Cdd:PTZ00468 336 gIVLLPEGLI-EFIPEFE----TLIKEL 358
|
|
| PRK06555 |
PRK06555 |
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated |
82-240 |
7.16e-07 |
|
pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Validated
Pssm-ID: 180620 [Multi-domain] Cd Length: 403 Bit Score: 50.39 E-value: 7.16e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 82 AKKIKSLRIDVLIMAGGDGSlqflNT--------LSE--FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRN 151
Cdd:PRK06555 105 AERLAADGVDILHTIGGDDT----NTtaadlaayLAEngYDLTVVGLPKTIDNDVVPIRQSLGAWTAAEQGARFFDNVIN 180
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 152 TGRALPgRVFMV-EILGGYCGELTLQSAIK--------------------SNADIALIPESQMPLETLAERVKHKLTQQN 210
Cdd:PRK06555 181 EHSANP-RMLIIhEVMGRNCGWLTAATARAyrewldrqeyvpgfglsaerWDIHAVYLPEMAFDLEAEAERLKAVMDEVG 259
|
170 180 190
....*....|....*....|....*....|
gi 490994151 211 SVVILCSEGytreyspgfqGAIDTMIKQLE 240
Cdd:PRK06555 260 NVNIFLSEG----------AGLDAIVAEME 279
|
|
| PLN02564 |
PLN02564 |
6-phosphofructokinase |
81-224 |
2.10e-06 |
|
6-phosphofructokinase
Pssm-ID: 178178 Cd Length: 484 Bit Score: 48.98 E-value: 2.10e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 81 IAKKIKSLRIDVLIMAGGDGSLQFLNTLSE------FDINCFGVGMTIDNDVYGSDYTIGFSTACEQIIKEVSRLRNTGR 154
Cdd:PLN02564 168 IVDSIQDRGINQVYIIGGDGTQKGASVIYEeirrrgLKVAVAGIPKTIDNDIPVIDKSFGFDTAVEEAQRAINAAHVEAE 247
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 490994151 155 ALPGRVFMVEILGGYCGELTLQSAIKS-NADIALIPESQMPLE---TLAERVKHKLTQQNSVVILCSEGYTREY 224
Cdd:PLN02564 248 SVENGIGLVKLMGRYSGFIAMYATLASrDVDCCLIPESPFYLEgkgGLFEFIEKRLKENGHMVIVVAEGAGQDL 321
|
|
| PLN02251 |
PLN02251 |
pyrophosphate-dependent phosphofructokinase |
1-190 |
1.18e-05 |
|
pyrophosphate-dependent phosphofructokinase
Pssm-ID: 215140 Cd Length: 568 Bit Score: 46.71 E-value: 1.18e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 1 MKIGMVISGGDVSGINNFIFQI-----ARLASADITLFNGGIPGLLDKNHHEVA------WRDLVDFSiasipIITSGR- 68
Cdd:PLN02251 97 LKIGVVLSGGQAPGGHNVISGIfdylqEHAKGSVLYGFKGGPAGIMKCKYVELTaefiypYRNQGGFD-----MICSGRd 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 490994151 69 ---TSRRLLRSEyETIAKkiksLRIDVLIMAGGDGSlqflNT----LSEF------DINCFGVGMTIDNDVYGSDYTI-- 133
Cdd:PLN02251 172 kieTPEQFKQAE-ETATK----LDLDGLVVIGGDDS----NTnaclLAEYfraknlKTRVIGCPKTIDGDLKSKEVPTsf 242
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 490994151 134 GFSTAC----EQIIKEVSRLRNTGRALpgrvFMVEILGGYCGELTLQSAIKSNADIALIPE 190
Cdd:PLN02251 243 GFDTACkiysEMIGNVMIDARSTGKYY----HFVRLMGRAASHITLECALQTHPNITIIGE 299
|
|
| |
