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Conserved domains on  [gi|491007486|ref|WP_004869202|]
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MULTISPECIES: phosphate ABC transporter permease PstA [Raoultella]

Protein Classification

phosphate ABC transporter permease PstA( domain architecture ID 11485290)

phosphate ABC transporter permease PstA is the transmembrane subunit (TM) found in periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter for phosphate; ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment; the captured solute is delivered to a gated translocation pathway formed by the two TMs

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
pstA PRK11268
phosphate ABC transporter permease PstA;
1-295 0e+00

phosphate ABC transporter permease PstA;


:

Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 552.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   1 MATIELQTSTELAESRRKMQAKRRLKNRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALFTEMTPPPNTAGGGLA 80
Cdd:PRK11268   1 MATVEMQNTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITLGIDGMSLALFTEMTPPPNTAGGGLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  81 NALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIAL 160
Cdd:PRK11268  81 NAIAGSGLLILWATVVGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 161 ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST 240
Cdd:PRK11268 161 ALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLFTALSNQFWST 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491007486 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKNKH 295
Cdd:PRK11268 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKKKH 295
 
Name Accession Description Interval E-value
pstA PRK11268
phosphate ABC transporter permease PstA;
1-295 0e+00

phosphate ABC transporter permease PstA;


Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 552.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   1 MATIELQTSTELAESRRKMQAKRRLKNRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALFTEMTPPPNTAGGGLA 80
Cdd:PRK11268   1 MATVEMQNTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITLGIDGMSLALFTEMTPPPNTAGGGLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  81 NALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIAL 160
Cdd:PRK11268  81 NAIAGSGLLILWATVVGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 161 ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST 240
Cdd:PRK11268 161 ALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLFTALSNQFWST 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491007486 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKNKH 295
Cdd:PRK11268 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKKKH 295
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 40-292 3.53e-108

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 314.28  E-value: 3.53e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  40 FGLFWLIWILMSTVTRGIDGMSLALFTEMtPPPNTAGGGLANALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKSALAE 119
Cdd:COG0581    1 LALLPLVWILGTVLVKGLPALSWEFLTSS-PSPGPEGGGILPAIVGTLLLVLLATLIAVPLGVLAAIYLAEYARGGRLAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 120 VIRFINDILLSAPSIVVGLFVYTIVVAQMQ-HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMI 198
Cdd:COG0581   80 LIRFAIDVLAGVPSIVYGLFGYALFVLTLGlGFSLLAGALALALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 199 SAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLC 278
Cdd:COG0581  160 RKVVLPAALPGILTGVILAIARAAGETAPLLFTAGVSPFLPLSLFDPFATLPVHIYNLASSPYPAAQELAWAAALVLLLL 239

                        250
                 ....*....|....
gi 491007486 279 VLLLNILARVVFAK 292
Cdd:COG0581  240 VLLLNLLARLLRRR 253
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 27-294 1.04e-80

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 245.22  E-value: 1.04e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   27 NRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALFTEmTPPPNTAGGGLANALAGSGLLILWSTVFGTPLGIMAGI 106
Cdd:TIGR00974   1 DKIFTFISLLSALLALLPLIWILWYILIKGLPALNLEFFTK-SPTPTGAEGGIGPAIVGTLLLTLLAIVIAVPLGIGAAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  107 YLAEYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQ--HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLR 184
Cdd:TIGR00974  80 YLAEYANGSRFTKIIRFAVDILAGVPSIVVGLFGYGFFVLTYLggGFSLLAGALALALLILPVIIRTTEEALKAVPKDLR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  185 EAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFA-MSPFAE 263
Cdd:TIGR00974 160 EASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAGETAPLLFTAGGSAFTPPNLFDPFATLPVLIYNLAsEGPYVE 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 491007486  264 WQQLAWAGVLLITLCVLLLNILARVVFAKNK 294
Cdd:TIGR00974 240 AQQLAWAAALVLIVLVLLLNLIARLLRRRFK 270
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 83-238 2.98e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 80.79  E-value: 2.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  83 LAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKsaLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQ----HFSGWAGVI 158
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK--LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilPGLGLPALI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFW 238
Cdd:cd06261   79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 101-232 1.55e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 70.41  E-value: 1.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  101 GIMAGIYLAEYgRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIALALLQVPIVIRTTENMLKLVP 180
Cdd:pfam00528   1 GIPLGIIAALR-RGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLP 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 491007486  181 DSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTA 232
Cdd:pfam00528  80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG 131
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 83-224 5.08e-07

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 49.08  E-value: 5.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  83 LAGSGLLILWSTVFGTPLGimAGIYLAEYGRKSAlaeVIRFINdILLSAPSIVVGLFVYTIVVAQMQH------FSGWAG 156
Cdd:NF038017   2 LRVSGTATLIAALIGIPLG--ALLALRRFPGRRL---VISLLN-TLMGLPPVVVGLIVYLLLSRSGPLgflgllYTPTAM 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491007486 157 VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAItLKASVSGIMTGILLAIARIAGE 224
Cdd:NF038017  76 IIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL-LKEARFALLAAVLAGFGRAISE 142
 
Name Accession Description Interval E-value
pstA PRK11268
phosphate ABC transporter permease PstA;
1-295 0e+00

phosphate ABC transporter permease PstA;


Pssm-ID: 183065 [Multi-domain]  Cd Length: 295  Bit Score: 552.75  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   1 MATIELQTSTELAESRRKMQAKRRLKNRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALFTEMTPPPNTAGGGLA 80
Cdd:PRK11268   1 MATVEMQNTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFWLIWILMSTITLGIDGMSLALFTEMTPPPNTAGGGLA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  81 NALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIAL 160
Cdd:PRK11268  81 NAIAGSGLLILWATVVGTPLGIMAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 161 ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWST 240
Cdd:PRK11268 161 ALLQIPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGVLLAIARIAGETAPLLFTALSNQFWST 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491007486 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKNKH 295
Cdd:PRK11268 241 DMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLCVLLLNILARVVFAKKKH 295
PstA COG0581
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 40-292 3.53e-108

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440346 [Multi-domain]  Cd Length: 259  Bit Score: 314.28  E-value: 3.53e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  40 FGLFWLIWILMSTVTRGIDGMSLALFTEMtPPPNTAGGGLANALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKSALAE 119
Cdd:COG0581    1 LALLPLVWILGTVLVKGLPALSWEFLTSS-PSPGPEGGGILPAIVGTLLLVLLATLIAVPLGVLAAIYLAEYARGGRLAR 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 120 VIRFINDILLSAPSIVVGLFVYTIVVAQMQ-HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMI 198
Cdd:COG0581   80 LIRFAIDVLAGVPSIVYGLFGYALFVLTLGlGFSLLAGALALALLMLPVVIRTTEEALRLVPNSLREASYALGATKWQTI 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 199 SAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLLITLC 278
Cdd:COG0581  160 RKVVLPAALPGILTGVILAIARAAGETAPLLFTAGVSPFLPLSLFDPFATLPVHIYNLASSPYPAAQELAWAAALVLLLL 239

                        250
                 ....*....|....
gi 491007486 279 VLLLNILARVVFAK 292
Cdd:COG0581  240 VLLLNLLARLLRRR 253
3a0107s02c TIGR00974
phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of ...
 27-294 1.04e-80

phosphate ABC transporter, permease protein PstA; This model describes PtsA, one of a pair of permease proteins in the ABC (high affinity) phosphate transporter. In a number of species, this permease is fused with the PtsC protein (TIGR02138). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273373  Cd Length: 271  Bit Score: 245.22  E-value: 1.04e-80
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   27 NRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALFTEmTPPPNTAGGGLANALAGSGLLILWSTVFGTPLGIMAGI 106
Cdd:TIGR00974   1 DKIFTFISLLSALLALLPLIWILWYILIKGLPALNLEFFTK-SPTPTGAEGGIGPAIVGTLLLTLLAIVIAVPLGIGAAI 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  107 YLAEYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQ--HFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLR 184
Cdd:TIGR00974  80 YLAEYANGSRFTKIIRFAVDILAGVPSIVVGLFGYGFFVLTYLggGFSLLAGALALALLILPVIIRTTEEALKAVPKDLR 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  185 EAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFA-MSPFAE 263
Cdd:TIGR00974 160 EASLALGATKWQTIFKVVLPAALPGILTGIILSIARAAGETAPLLFTAGGSAFTPPNLFDPFATLPVLIYNLAsEGPYVE 239

                         250       260       270
                  ....*....|....*....|....*....|.
gi 491007486  264 WQQLAWAGVLLITLCVLLLNILARVVFAKNK 294
Cdd:TIGR00974 240 AQQLAWAAALVLIVLVLLLNLIARLLRRRFK 270
PstC COG0573
ABC-type phosphate transport system, permease component [Inorganic ion transport and ...
 13-253 5.64e-32

ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440338 [Multi-domain]  Cd Length: 303  Bit Score: 120.19  E-value: 5.64e-32
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  13 AESRRKMQAKRRLKNRIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMS----LALFTEMTPPPNTAGG--GLANALAGS 86
Cdd:COG0573    3 SSRLRPRRRRRRLGDRLFRGLLLLAALLSILILLLIVLFLLIESLPAFQevglLEFLTGTEWNPVSSNGefGILPLIVGT 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  87 GLLILWSTVFGTPLGIMAGIYLAEYGRKSaLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGW--------AGVI 158
Cdd:COG0573   83 LLVSLIALLIAVPLGLGIAIFLSEYAPPR-LRRILKPAIELLAGIPSVVYGFWGLFVLVPLLRDLFPWppsgfsllTAGI 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGET-APLLFTALSNQF 237
Cdd:COG0573  162 VLAIMILPTITSLSRDALRAVPRSLREAALALGATRWETIRKVVLPAARSGIIAAVILGLGRALGETmAVLMVAGNAPQI 241

                        250
                 ....*....|....*.
gi 491007486 238 wSTDMMQPIANLPVTI 253
Cdd:COG0573  242 -PFSLFDPGRTLTALI 256
phosphate_pstC TIGR02138
phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity ...
 28-225 9.48e-22

phosphate ABC transporter, permease protein PstC; The typical operon for the high affinity inorganic phosphate ABC transporter encodes an ATP-binding protein, a phosphate-binding protein, and two permease proteins. This family consists of one of the two permease proteins, PstC, which is homologous to PstA (TIGR00974). In the model bacterium Escherichia coli, this transport system is induced when the concentration of extrallular inorganic phosphate is low. A constitutive, lower affinity transporter operates otherwise. [Transport and binding proteins, Anions]


Pssm-ID: 273992 [Multi-domain]  Cd Length: 295  Bit Score: 92.33  E-value: 9.48e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   28 RIALTLSMGTMVFGLFWLIWILMSTVTRGIDGMSLALF---TEMTPPPNTAGG--GLANALAGSGLLILWSTVFGTPLGI 102
Cdd:TIGR02138   5 KGLLLFSAVIIVLVLLLIVLFLLYEAIPAFEKNGILNFltgTVWDPGSGPVQEqyGALPLIVGTLITSLIALLIAVPVGI 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  103 MAGIYLAEYGRKSaLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQ-HFSGW----------------AGVIALALLQV 165
Cdd:TIGR02138  85 GIAIFLSEIAPKR-VRSVLKPVVELLAGIPSVVYGFWGLFVLVPFLKpHFQPFlgsnlgliplfggpilTAGIVLAIMIL 163

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  166 PIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGET 225
Cdd:TIGR02138 164 PTIASISRDALRAVPRSYKEASYALGATKWETIRRVILPAARSGIVGAVVLGLGRALGET 223
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 83-238 2.98e-18

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 80.79  E-value: 2.98e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  83 LAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKsaLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQ----HFSGWAGVI 158
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGK--LDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLLGwgilPGLGLPALI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 159 ALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTALSNQFW 238
Cdd:cd06261   79 LALLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPG 158
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 101-232 1.55e-14

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 70.41  E-value: 1.55e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  101 GIMAGIYLAEYgRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGVIALALLQVPIVIRTTENMLKLVP 180
Cdd:pfam00528   1 GIPLGIIAALR-RGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLP 79

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|..
gi 491007486  181 DSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTA 232
Cdd:pfam00528  80 SDLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLG 131
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
7-230 1.21e-09

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 58.63  E-value: 1.21e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486   7 QTSTELAESRRKMQAKRRLKNRIALTLSMGTMVFGLFW-LIWILMSTVTRGID-GMSLALFTEMTPPPNTAGgglanALA 84
Cdd:COG1178  267 RYATVGGRARRPRRVKLGRWRWLALALCLLLVLLGLLLpLLALLLWSLTKALDdNLTLDNYRFVLLDPSLLR-----ALL 341

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  85 GSGLLILWSTVFGTPLGIMAGIYLAEygRKSALAEVIRFINDILLSAPSIVVGL-FVYTIVVAQMQHFSGWAG--VIALA 161
Cdd:COG1178  342 NSLLLALLAALLAVLLALLLAYLVRR--RRGRLARLLDRLAMLPYAVPGIVLGLgLLLLFNRPLPLLLYGTLAilVLAYV 419

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 162 LLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGE-TAPLLF 230
Cdd:COG1178  420 VRFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALLVFVTSMKElSATLLL 489
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 78-219 5.67e-08

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 52.81  E-value: 5.67e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  78 GLANALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRKsaLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHFSGWAGV 157
Cdd:COG1177   58 RLLDALLNSLLIALLSTLLATVLGTPAALALARYRFR--GRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLI 135

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491007486 158 IALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIA 219
Cdd:COG1177  136 LAHVVFTLPFVVLVVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALLAFT 197
ABC_perm1 NF038017
ABC transporter permease; Proteins of this family are the permease subunit of an ABC ...
 83-224 5.08e-07

ABC transporter permease; Proteins of this family are the permease subunit of an ABC transporter complex, which may be involved in tungstate uptake.


Pssm-ID: 411610 [Multi-domain]  Cd Length: 184  Bit Score: 49.08  E-value: 5.08e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  83 LAGSGLLILWSTVFGTPLGimAGIYLAEYGRKSAlaeVIRFINdILLSAPSIVVGLFVYTIVVAQMQH------FSGWAG 156
Cdd:NF038017   2 LRVSGTATLIAALIGIPLG--ALLALRRFPGRRL---VISLLN-TLMGLPPVVVGLIVYLLLSRSGPLgflgllYTPTAM 75

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 491007486 157 VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAItLKASVSGIMTGILLAIARIAGE 224
Cdd:NF038017  76 IIAQAVLALPIVAGLTLAAVQGLDPELRLQILSLGATRWQALWTL-LKEARFALLAAVLAGFGRAISE 142
OpuBB COG1174
ABC-type proline/glycine betaine transport system, permease component [Amino acid transport ...
 60-214 7.86e-06

ABC-type proline/glycine betaine transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440787 [Multi-domain]  Cd Length: 212  Bit Score: 45.82  E-value: 7.86e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  60 MSLALFTEMTpppnTAGGGLANALAGSGLLILWSTVFGTPLGIMAGIYLAEYGRksaLAEVIRFINDILLSAPSIvvGLF 139
Cdd:COG1174    1 MNLSLIEWLA----DNRDGILALLLEHLLLVLLALLIALLIAVPLGILITRRRR---LAGLVLGVANILQTIPSL--ALL 71

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491007486 140 VYTIVVAQmqhFSGWAGVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGI 214
Cdd:COG1174   72 ALLIPLLG---IGPAPAIIALVLYALLPILRNTYTGLRSVDPAVVEAARGMGMTPWQRLWRVELPLALPVILAGI 143
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 91-234 8.01e-06

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 46.28  E-value: 8.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  91 LWSTVFGTPLGIMAGIYLAEY---GRKsalaeVIRFINDILLSAPSIVVG-----LFVYTIVVAQMQH-------FSGWA 155
Cdd:COG0555   64 LIAALINLVFGLPLAWVLVRYrfpGKR-----LVDALVDLPFALPTAVAGialllLFGPNGWLGQLLAplgikvaFTPLG 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 156 GVIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIAR----------IAG-- 223
Cdd:COG0555  139 IVLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFALAFARalgefgavifIAGnl 218

                        170
                 ....*....|....*.
gi 491007486 224 ----ETAPLL-FTALS 234
Cdd:COG0555  219 pmktEILPLLiYLKLE 234
cysT CHL00187
sulfate transport protein; Provisional
 24-224 3.98e-05

sulfate transport protein; Provisional


Pssm-ID: 214388 [Multi-domain]  Cd Length: 237  Bit Score: 43.85  E-value: 3.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  24 RLKNRIALTLSMGTMVFGLFWLIWILMStvtRGIDGMSLALFTEMTPPPNTAGGGLANALAgsglliLWSTVFGTPLGIM 103
Cdd:CHL00187   7 SLKFSSIYIISLSYIIFLLVLPILALLI---KASQQPWSDFLQKATEPIALSAYSLTLSMA------LIAALINGFFGLL 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 104 AGIYLAEY---GRKSALAEVirfinDILLSAPSIVVGLFVYTIVVAQ--MQHFSGWAGV--------IALALLQV--PIV 168
Cdd:CHL00187  78 IAWVLVRYnfpGKRLLDAAV-----DLPFALPTSVAGLTLATVYGDNgwIGHLLSHLGIqivftklgVLLAMIFVsfPFV 152

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 491007486 169 IRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGE 224
Cdd:CHL00187 153 VRTIQPVLQEIEKELEEAAWSLGASPWQTFWKVIFPPLIPALLTGLALTFSRAIGE 208
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
19-217 1.33e-04

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 43.23  E-value: 1.33e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  19 MQAKRRLKNRIALTLSMGTMVFGLFW-LIWILMSTVTRGIDGMSLALFTEMTPppntaggglaNALAGSGLLILWSTVFG 97
Cdd:COG1178    1 MSTRPRRRPRLLLLLLALLLALLVLLpLLALLLRAFTDGLANFWALLSDPYLW----------RALGNTLLLALLVTLLS 70

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  98 TPLGIMAGIYLAEY---GRKsalaeVIRFINDILLSAPSIVVG-----LFVYTIVVAQMQH----------FSGWAGVIA 159
Cdd:COG1178   71 LLLGVPLAWLLARTdfpGRR-----LLRWLLLLPLALPPYVVAlawiaLFGPNGLLNTLLRalfgleppdiYGLGGIILV 145

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 491007486 160 LALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLA 217
Cdd:COG1178  146 LVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLV 203
modB PRK09421
molybdate ABC transporter permease subunit;
154-224 2.10e-04

molybdate ABC transporter permease subunit;


Pssm-ID: 181841  Cd Length: 229  Bit Score: 41.83  E-value: 2.10e-04
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 491007486 154 WAG-VIALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGE 224
Cdd:PRK09421  92 WRGaALAAAVMAFPLMVRAIRLSLEAVDRKLEQAARTLGASPWRVFFTITLPLTLPGIIAGTVLAFARSLGE 163
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 79-219 1.14e-03

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 40.05  E-value: 1.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  79 LANALAGSGLLILWSTVFGTPLGIMAGIYLAeYGRKSALAEVIRFINDILLSAPSIVVGLFVYTIVVAQMQHF--SGWAG 156
Cdd:COG0601   91 IAERLPVTLELALLALLLALLIGIPLGILAA-LRRGSWLDRLITVLALLGISIPSFWLGLLLILLFAVKLGWLpvSGRVS 169

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 157 ---------------VIALALLQVPIVIRTT-ENMLklvpDSLRE----AAYALGTPKWKMISAITLKASVSGIMTGILL 216
Cdd:COG0601  170 pwedfldalrhlilpALTLALGSLAGIARLTrSSML----EVLGQdyvrTARAKGLSERRVLLRHALRNALIPVVTVLGL 245


                 ...
gi 491007486 217 AIA 219
Cdd:COG0601  246 QLG 248
pstC PRK11275
phosphate ABC transporter permease PstC;
155-230 1.23e-03

phosphate ABC transporter permease PstC;


Pssm-ID: 183070  Cd Length: 319  Bit Score: 39.68  E-value: 1.23e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491007486 155 AGVIaLALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLF 230
Cdd:PRK11275 173 AGVI-LAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRIVLPFTKNGVIGGVMLGLGRALGETMAVTF 247
PRK10971 PRK10971
sulfate/thiosulfate ABC transporter permease CysT;
154-242 3.30e-03

sulfate/thiosulfate ABC transporter permease CysT;


Pssm-ID: 182873  Cd Length: 277  Bit Score: 38.58  E-value: 3.30e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486 154 WAGV-IALALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAIARIAGETAPLLFTA 232
Cdd:PRK10971 140 WLGIaVAMAFTSIPFVVRTVQPVLEELGPEYEEAAETLGATRWQSFRKVVLPELSPALLAGVALSFTRSLGEFGAVIFIA 219

                         90
                 ....*....|
gi 491007486 233 lSNQFWSTDM 242
Cdd:PRK10971 220 -GNIAWKTEV 228
PRK10952 PRK10952
proline/glycine betaine ABC transporter permease ProW;
89-214 9.63e-03

proline/glycine betaine ABC transporter permease ProW;


Pssm-ID: 236805  Cd Length: 355  Bit Score: 36.99  E-value: 9.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491007486  89 LILWSTVFGTPLGIMAGIYLAeygRKSALAEVIRFINDILLSAPSivvglFVYTIVVAQMQHFSGWAGVIALALLQVPIV 168
Cdd:PRK10952 152 LVLTALLFCIVIGLPLGIWLA---RSPRAAKIIRPLLDAMQTTPA-----FVYLVPIVMLFGIGNVPGVVVTIIFALPPI 223

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*.
gi 491007486 169 IRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGI 214
Cdd:PRK10952 224 VRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGV 269
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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