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Conserved domains on  [gi|491022322|ref|WP_004884020|]
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MULTISPECIES: RcnB family protein [Acinetobacter]

Protein Classification

RcnB family protein( domain architecture ID 10009312)

RcnB family protein similar to Escherichia coli nickel/cobalt homeostasis protein RcnB that may act by modulating RcnA-mediated export of nickel and cobalt ions to avoid excess efflux

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RcnB COG5455
Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];
1-133 1.29e-24

Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];


:

Pssm-ID: 444206 [Multi-domain]  Cd Length: 121  Bit Score: 90.93  E-value: 1.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491022322   1 MKK-LFTILALSITVLTTSMASFADPPFDRGHGQkgpkGGPRGEWNDRGHKHDRddhedrfrderrmrEERGFERLKQHR 79
Cdd:COG5455    1 MKKkLIILALLAASLLAAASAAFAQPPGPDRRGH----DRRRDDRHDDPGHRDK--------------HRGAGPGEDYKR 62

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491022322  80 WQPGYVMPQHYRGNGYKV-DYRDNNLPKPDRNQQWYKINNDYILVDTDSNSIVSI 133
Cdd:COG5455   63 WRRGDRLPPEYRGRRYVVnDWRRYGLPAPPRGYHWVRVGGDYVLVAIATGIIVSI 117
 
Name Accession Description Interval E-value
RcnB COG5455
Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];
1-133 1.29e-24

Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];


Pssm-ID: 444206 [Multi-domain]  Cd Length: 121  Bit Score: 90.93  E-value: 1.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491022322   1 MKK-LFTILALSITVLTTSMASFADPPFDRGHGQkgpkGGPRGEWNDRGHKHDRddhedrfrderrmrEERGFERLKQHR 79
Cdd:COG5455    1 MKKkLIILALLAASLLAAASAAFAQPPGPDRRGH----DRRRDDRHDDPGHRDK--------------HRGAGPGEDYKR 62

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491022322  80 WQPGYVMPQHYRGNGYKV-DYRDNNLPKPDRNQQWYKINNDYILVDTDSNSIVSI 133
Cdd:COG5455   63 WRRGDRLPPEYRGRRYVVnDWRRYGLPAPPRGYHWVRVGGDYVLVAIATGIIVSI 117
RcnB pfam11776
Nickel/cobalt transporter regulator; RcnB is a family of Proteobacteria proteins. RcnB is ...
 83-132 1.66e-13

Nickel/cobalt transporter regulator; RcnB is a family of Proteobacteria proteins. RcnB is required for maintaining metal ion homeostasis, in conjunction with the efflux pump RcnA, family NicO, pfam03824.


Pssm-ID: 432066  Cd Length: 51  Bit Score: 60.66  E-value: 1.66e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 491022322   83 GYVMPQHYRGNGYKV-DYRDNNLPKPDRNQQWYKINNDYILVDTDSNSIVS 132
Cdd:pfam11776   1 GDRLPPEYRGRRYVVdDYRRYHLPAPPRGYHWVRIGGDYVLVAIATGRIVD 51
T3SS_CigR_fam NF040487
anti-virulence regulator CigR family protein; Members of this family are full-length homologs ...
 5-56 5.66e-03

anti-virulence regulator CigR family protein; Members of this family are full-length homologs of CigR, an inner membrane protein that appears to act as an anti-virulence factor. It was previously thought to be exported as a type III secretion system (T3SS) effector. A low-complexity, variable length repetitive region, rich in Gly, Pro, His, Lys, and Asn, separates a short, hydrophobic N-terminal domain from a longer, well-conserved C-terminal domain. A short stretch of that C-terminal domain, about 25 amino acids long, shows similarity to the C-terminal half of the domain described by Pfam model PF11776.10 (RcnB), but similarity between CigR and RcnB is not extensive.


Pssm-ID: 468512 [Multi-domain]  Cd Length: 147  Bit Score: 34.81  E-value: 5.66e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491022322   5 FTILALSITVLTTSMASFADPPFDRGHGQKG---PKGGPRGEWNDRGHKHDRDDH 56
Cdd:NF040487   1 LAALAAVLSLALGSAPALADPGNGKGNGNGNgghGNHGNKGNGGNGGKKKNGGDP 55
 
Name Accession Description Interval E-value
RcnB COG5455
Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];
1-133 1.29e-24

Periplasmic regulator RcnB of Ni and Co efflux [Inorganic ion transport and metabolism];


Pssm-ID: 444206 [Multi-domain]  Cd Length: 121  Bit Score: 90.93  E-value: 1.29e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491022322   1 MKK-LFTILALSITVLTTSMASFADPPFDRGHGQkgpkGGPRGEWNDRGHKHDRddhedrfrderrmrEERGFERLKQHR 79
Cdd:COG5455    1 MKKkLIILALLAASLLAAASAAFAQPPGPDRRGH----DRRRDDRHDDPGHRDK--------------HRGAGPGEDYKR 62

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491022322  80 WQPGYVMPQHYRGNGYKV-DYRDNNLPKPDRNQQWYKINNDYILVDTDSNSIVSI 133
Cdd:COG5455   63 WRRGDRLPPEYRGRRYVVnDWRRYGLPAPPRGYHWVRVGGDYVLVAIATGIIVSI 117
RcnB pfam11776
Nickel/cobalt transporter regulator; RcnB is a family of Proteobacteria proteins. RcnB is ...
 83-132 1.66e-13

Nickel/cobalt transporter regulator; RcnB is a family of Proteobacteria proteins. RcnB is required for maintaining metal ion homeostasis, in conjunction with the efflux pump RcnA, family NicO, pfam03824.


Pssm-ID: 432066  Cd Length: 51  Bit Score: 60.66  E-value: 1.66e-13
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|.
gi 491022322   83 GYVMPQHYRGNGYKV-DYRDNNLPKPDRNQQWYKINNDYILVDTDSNSIVS 132
Cdd:pfam11776   1 GDRLPPEYRGRRYVVdDYRRYHLPAPPRGYHWVRIGGDYVLVAIATGRIVD 51
T3SS_CigR_fam NF040487
anti-virulence regulator CigR family protein; Members of this family are full-length homologs ...
 5-56 5.66e-03

anti-virulence regulator CigR family protein; Members of this family are full-length homologs of CigR, an inner membrane protein that appears to act as an anti-virulence factor. It was previously thought to be exported as a type III secretion system (T3SS) effector. A low-complexity, variable length repetitive region, rich in Gly, Pro, His, Lys, and Asn, separates a short, hydrophobic N-terminal domain from a longer, well-conserved C-terminal domain. A short stretch of that C-terminal domain, about 25 amino acids long, shows similarity to the C-terminal half of the domain described by Pfam model PF11776.10 (RcnB), but similarity between CigR and RcnB is not extensive.


Pssm-ID: 468512 [Multi-domain]  Cd Length: 147  Bit Score: 34.81  E-value: 5.66e-03
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 491022322   5 FTILALSITVLTTSMASFADPPFDRGHGQKG---PKGGPRGEWNDRGHKHDRDDH 56
Cdd:NF040487   1 LAALAAVLSLALGSAPALADPGNGKGNGNGNgghGNHGNKGNGGNGGKKKNGGDP 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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