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Conserved domains on  [gi|491025153|ref|WP_004886846|]
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MULTISPECIES: ECA polysaccharide chain length modulation protein [Klebsiella]

Protein Classification

ECA polysaccharide chain length modulation protein( domain architecture ID 11485441)

ECA polysaccharide chain length modulation protein modulates the polysaccharide chain length of enterobacterial common antigen (ECA)

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
PRK11638 PRK11638
ECA polysaccharide chain length modulation protein;
8-346 0e+00

ECA polysaccharide chain length modulation protein;


:

Pssm-ID: 236943 [Multi-domain]  Cd Length: 342  Bit Score: 701.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   8 AQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIKAD 87
Cdd:PRK11638   1 KPAVSAENELDIRGLCRTLWAGKLWIIGMALLFALIALGYSFLARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIRSN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  88 LA-SVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKQRQSGNARADAAMLDDLINNIQFMPGDAAKSVNDSVKLTAE 166
Cdd:PRK11638  81 SAlSADQPSIMDEAYKEFIMQLAAYDTRREFWLQTDYYKQRMEGNAKADAALLDELINNIQFTPGDDTKAINDSVKLIAE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 167 TGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHNISRSETDV 246
Cdd:PRK11638 161 TAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEAVAKAIYDREVNSVEQALKIAEQQGISRSQTDV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 247 PADQLPDSELFLLGRPMLQARLENLQAVGPEYDLDYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRVFLM 326
Cdd:PRK11638 241 PAEELPDSELFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLATLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLM 320
                        330       340
                 ....*....|....*....|
gi 491025153 327 VMWGIVGALIGAGVALSRRR 346
Cdd:PRK11638 321 IMWGAVGALVGAGVALTRRR 340
 
Name Accession Description Interval E-value
PRK11638 PRK11638
ECA polysaccharide chain length modulation protein;
8-346 0e+00

ECA polysaccharide chain length modulation protein;


Pssm-ID: 236943 [Multi-domain]  Cd Length: 342  Bit Score: 701.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   8 AQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIKAD 87
Cdd:PRK11638   1 KPAVSAENELDIRGLCRTLWAGKLWIIGMALLFALIALGYSFLARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIRSN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  88 LA-SVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKQRQSGNARADAAMLDDLINNIQFMPGDAAKSVNDSVKLTAE 166
Cdd:PRK11638  81 SAlSADQPSIMDEAYKEFIMQLAAYDTRREFWLQTDYYKQRMEGNAKADAALLDELINNIQFTPGDDTKAINDSVKLIAE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 167 TGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHNISRSETDV 246
Cdd:PRK11638 161 TAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEAVAKAIYDREVNSVEQALKIAEQQGISRSQTDV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 247 PADQLPDSELFLLGRPMLQARLENLQAVGPEYDLDYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRVFLM 326
Cdd:PRK11638 241 PAEELPDSELFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLATLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLM 320
                        330       340
                 ....*....|....*....|
gi 491025153 327 VMWGIVGALIGAGVALSRRR 346
Cdd:PRK11638 321 IMWGAVGALVGAGVALTRRR 340
WzzB COG3765
LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope ...
3-345 4.40e-156

LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442979 [Multi-domain]  Cd Length: 364  Bit Score: 442.10  E-value: 4.40e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   3 QPLPGAQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNL 82
Cdd:COG3765    8 QLYPNQYPPSQDDEIDLFELLRTLWQGKLWIIGITLLFALLALVYAFLLPQKWTSTAIVDPPTVNELGGYYSQRQFLRNL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  83 DIKadlaSVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKQRQSGNARADAAMLDDLINNIQFMPGDAAKS----VN 158
Cdd:COG3765   88 DVK----SVDPPVISSELFNEFIKQLSSYDLRREFLLQSDYYKQLQEGDEKEDAALLDELINNISITPPDDKKKsspyTN 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 159 DSVKLTAETGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHN 238
Cdd:COG3765  164 YSVSFTAETPEDAQQLLRGYIDFANQRVLKELNEELQGAIAARLQSLKAQIKRLEEVAKAQRQRRIERLKYALKIAQAAG 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 239 ISR---SETDVPADQLPDSELFLLGRPMLQARLENLQAVGPEYDL--DYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEE 313
Cdd:COG3765  244 IKKpvySNGQTPAVKLDPSYLFLLGTDALQAELEILKARGDDYPLnaDLYQLQAQLAQLNALPIDDVGFQPFRYLRTPEE 323
                        330       340       350
                 ....*....|....*....|....*....|..
gi 491025153 314 PVKRDSPRRVFLMVMWGIVGALIGAGVALSRR 345
Cdd:COG3765  324 PVKKDKPKRALILVLGALLGGMLGVGVVLIRH 355
Wzz pfam02706
Chain length determinant protein; This family includes proteins involved in lipopolysaccharide ...
15-83 3.52e-15

Chain length determinant protein; This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases.


Pssm-ID: 460658 [Multi-domain]  Cd Length: 90  Bit Score: 70.01  E-value: 3.52e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491025153   15 NELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPT----------VNMLGGYYSQQQFLRNLD 83
Cdd:pfam02706   1 DEIDLIELLGVLWKRKKLIILVTLLFTLLAAAYAFLATPKYTATAQILVPQkkgeagsllgSDLQAGLQLASTEIEILK 79
 
Name Accession Description Interval E-value
PRK11638 PRK11638
ECA polysaccharide chain length modulation protein;
8-346 0e+00

ECA polysaccharide chain length modulation protein;


Pssm-ID: 236943 [Multi-domain]  Cd Length: 342  Bit Score: 701.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   8 AQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIKAD 87
Cdd:PRK11638   1 KPAVSAENELDIRGLCRTLWAGKLWIIGMALLFALIALGYSFLARQEWSATAITDRPTVNMLGGYYSQQQFLRNLDIRSN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  88 LA-SVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKQRQSGNARADAAMLDDLINNIQFMPGDAAKSVNDSVKLTAE 166
Cdd:PRK11638  81 SAlSADQPSIMDEAYKEFIMQLAAYDTRREFWLQTDYYKQRMEGNAKADAALLDELINNIQFTPGDDTKAINDSVKLIAE 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 167 TGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHNISRSETDV 246
Cdd:PRK11638 161 TAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEAVAKAIYDREVNSVEQALKIAEQQGISRSQTDV 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 247 PADQLPDSELFLLGRPMLQARLENLQAVGPEYDLDYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRVFLM 326
Cdd:PRK11638 241 PAEELPDSELFLLGRPMLQARLENLQAVGPAFDLDYDQNRAMLATLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLM 320
                        330       340
                 ....*....|....*....|
gi 491025153 327 VMWGIVGALIGAGVALSRRR 346
Cdd:PRK11638 321 IMWGAVGALVGAGVALTRRR 340
WzzB COG3765
LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope ...
3-345 4.40e-156

LPS O-antigen chain length determinant protein, WzzB/FepE family [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442979 [Multi-domain]  Cd Length: 364  Bit Score: 442.10  E-value: 4.40e-156
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   3 QPLPGAQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNL 82
Cdd:COG3765    8 QLYPNQYPPSQDDEIDLFELLRTLWQGKLWIIGITLLFALLALVYAFLLPQKWTSTAIVDPPTVNELGGYYSQRQFLRNL 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  83 DIKadlaSVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKQRQSGNARADAAMLDDLINNIQFMPGDAAKS----VN 158
Cdd:COG3765   88 DVK----SVDPPVISSELFNEFIKQLSSYDLRREFLLQSDYYKQLQEGDEKEDAALLDELINNISITPPDDKKKsspyTN 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 159 DSVKLTAETGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHN 238
Cdd:COG3765  164 YSVSFTAETPEDAQQLLRGYIDFANQRVLKELNEELQGAIAARLQSLKAQIKRLEEVAKAQRQRRIERLKYALKIAQAAG 243
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 239 ISR---SETDVPADQLPDSELFLLGRPMLQARLENLQAVGPEYDL--DYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEE 313
Cdd:COG3765  244 IKKpvySNGQTPAVKLDPSYLFLLGTDALQAELEILKARGDDYPLnaDLYQLQAQLAQLNALPIDDVGFQPFRYLRTPEE 323
                        330       340       350
                 ....*....|....*....|....*....|..
gi 491025153 314 PVKRDSPRRVFLMVMWGIVGALIGAGVALSRR 345
Cdd:COG3765  324 PVKKDKPKRALILVLGALLGGMLGVGVVLIRH 355
PRK15471 PRK15471
chain length determinant protein WzzB; Provisional
12-344 1.36e-31

chain length determinant protein WzzB; Provisional


Pssm-ID: 185368 [Multi-domain]  Cd Length: 325  Bit Score: 121.01  E-value: 1.36e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  12 NVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVNMLGGYYSQQQFLRNldikadlasv 91
Cdd:PRK15471  13 HDPEQIDLIDLLVQLWRGKMTIIISVIVAIALAVGYLAVAKEKWTSTAIITQPDVGQIAGYNNAMNVLYG---------- 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  92 DQPSAMDEAYKEFIMQLASwdtrrdfwlqtdyykqrqsgnarADAAMLDDLIN-------NIQFMPGDAAKSVndSVKLT 164
Cdd:PRK15471  83 DNAPKVSDVQATLIGRFSS-----------------------AFSALAETLDNqeepeklTIEPSVKGQALPL--SVSYV 137
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 165 AETGQDANNLLRQYVAFASQRAAGHLNDELKGAWAARTVQMKAQVKRQEEVAEAIFNRRTHSVEQALKVAQQHNISRSET 244
Cdd:PRK15471 138 GQTAEGAQKKLAQYIQQVDDQVAKELEKDLKDNIALRTKTLQDSLETQEVVAQEQKDLRIKQIQEALQYANQANITKPQI 217
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 245 DvPADQLPDSELFLLGRPMLQARLENlQAVGP-EYDLDYDQNRAMLSTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRV 323
Cdd:PRK15471 218 Q-QTQDVTQDTLFLLGSEALESMIKH-EATRPlVFSPNYYQTRQNLLDIENLKVDEDDIHAYRYVMKPTLPVRRDSPKKA 295
                        330       340
                 ....*....|....*....|.
gi 491025153 324 FLMVMWGIVGALIGAGVALSR 344
Cdd:PRK15471 296 ITLVLAVLLGGMIGAGIVLGR 316
PRK10381 PRK10381
LPS O-antigen length regulator; Provisional
4-348 1.31e-23

LPS O-antigen length regulator; Provisional


Pssm-ID: 182422 [Multi-domain]  Cd Length: 377  Bit Score: 100.14  E-value: 1.31e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153   4 PLPGAQavnvENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPTVnmlggyySQQQFLRNLD 83
Cdd:PRK10381  18 PLASPS----NNEIDLFELISVLWKAKKTIIAITFAFACAGLLISFILPQKWTSTAVVTPPEL-------VQWQELEKTL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153  84 IKADLASVDQPSAMDEAYKEFIMQLASWDTRRDFWLQTDYYKqRQSGNARADAAMLDDLI----NNIQFMPGDAAKSVND 159
Cdd:PRK10381  87 TKLRVLDLDVKVDRSSLFNLFIKKFQSRSLLEEYLRSSPYVM-DQLKEAKIDELDLHRAIvalsEKMKAVDNNASKKKDE 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 160 -----SVKL--TAETGQDANNLLRQYVAFASQRAAGHLNDELKgawaaRTVQMKAQVKrQEEVA---EAIFNRRTHSVEQ 229
Cdd:PRK10381 166 eslytSWTLsfTAPTSEEAQDVLSGYINYISTIVVKEVLENIR-----NKLEIKTQFE-KEKLAmdrIKLKNQLDANIQR 239
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491025153 230 ---ALKVAQQHNISR---SETDVPADQlPDSELfLLGRPMLQARLENLQAVGPEYDLDYD-QNR----AMLSTLNVGptl 298
Cdd:PRK10381 240 lnySLSIANAAGIKKpvySNGQAVKDD-PDFSI-ALGADGLERKLEIEKSVTDVAEINGElRNRqyyvEQLKKLNIN--- 314
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 491025153 299 DPRFQTYRYLRTPEEPVKRDSPRRVFLMVMWGIVGALIGAG------VALSRRRVL 348
Cdd:PRK10381 315 DVNFTPFKYQLSPSLPVKKDGPGKALIVILAALIGGMLACGfvllrhAMRSRKQDL 370
Wzz pfam02706
Chain length determinant protein; This family includes proteins involved in lipopolysaccharide ...
15-83 3.52e-15

Chain length determinant protein; This family includes proteins involved in lipopolysaccharide (lps) biosynthesis. This family comprises the whole length of chain length determinant protein (or wzz protein) that confers a modal distribution of chain length on the O-antigen component of lps. This region is also found as part of bacterial tyrosine kinases.


Pssm-ID: 460658 [Multi-domain]  Cd Length: 90  Bit Score: 70.01  E-value: 3.52e-15
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 491025153   15 NELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATAITDRPT----------VNMLGGYYSQQQFLRNLD 83
Cdd:pfam02706   1 DEIDLIELLGVLWKRKKLIILVTLLFTLLAAAYAFLATPKYTATAQILVPQkkgeagsllgSDLQAGLQLASTEIEILK 79
GumC COG3206
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
1-59 1.42e-04

Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442439 [Multi-domain]  Cd Length: 687  Bit Score: 43.85  E-value: 1.42e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 491025153   1 MTQPLPgaQAVNVENELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATA 59
Cdd:COG3206    1 MNESSS--APPEEEDEIDLRDLLRILRRRKWLILLVFLLVLALALLYALLLPPVYEASA 57
YveK COG3944
Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];
16-59 2.52e-03

Capsular polysaccharide biosynthesis protein YveK [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443144 [Multi-domain]  Cd Length: 309  Bit Score: 39.28  E-value: 2.52e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....
gi 491025153  16 ELDIRGLFRALWAGKGWIVGGAVLFAAIVLVYTFFARQEWSATA 59
Cdd:COG3944    1 EMDLREYLRILRRRWWLILLLTLLGALAALASSFLITPVYQAST 44
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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