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Conserved domains on  [gi|491071253|ref|WP_004932877|]
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MULTISPECIES: gluconokinase [Acinetobacter]

Protein Classification

gluconokinase( domain architecture ID 10790049)

gluconokinase catalyzes the phosphoryl transfer from ATP to gluconate to form gluconate-6-phoshate

Gene Ontology:  GO:0046316|GO:0046177|GO:0005524
SCOP:  4003925

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 1-162 1.81e-90

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


:

Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 260.83  E-value: 1.81e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   1 MIVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCS 80
Cdd:COG3265    2 MVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLACS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  81 SLKHAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGE-AIVVDITLSPRQIIEQVTQ 159
Cdd:COG3265   82 ALKRSYRDRLREGNPDVRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEdAIVVDIDQPPEEIVAQILA 161


                 ...
gi 491071253 160 KLG 162
Cdd:COG3265  162 ALG 164
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 1-162 1.81e-90

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 260.83  E-value: 1.81e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   1 MIVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCS 80
Cdd:COG3265    2 MVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLACS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  81 SLKHAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGE-AIVVDITLSPRQIIEQVTQ 159
Cdd:COG3265   82 ALKRSYRDRLREGNPDVRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEdAIVVDIDQPPEEIVAQILA 161


                 ...
gi 491071253 160 KLG 162
Cdd:COG3265  162 ALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 2-146 1.64e-67

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 202.10  E-value: 1.64e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   2 IVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQ-MGQTAVFTCS 80
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLAsAGEGVVVACS 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  81 SLKHAYREILRAN--DQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGE--AIVVDI 146
Cdd:cd02021   81 ALKRIYRDILRGGaaNPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPGEDEedVIVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 4-156 1.27e-60

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 185.30  E-value: 1.27e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253    4 IAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCSSLK 83
Cdd:TIGR01313   2 VLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSALK 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491071253   84 HAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGEA--IVVDITLSPRQIIEQ 156
Cdd:TIGR01313  82 RHYRDILREAEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADETdvLRVDIDQPLEGVEED 156
gntK PRK11545
gluconokinase;
6-157 1.82e-52

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 164.50  E-value: 1.82e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   6 MGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCSSLKHA 85
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKH 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491071253  86 YREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGEA--IVVDItlspRQIIEQV 157
Cdd:PRK11545  81 YRDLLREGNPNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETdvLVVDI----DQPLEGV 150
SKI pfam01202
Shikimate kinase;
10-161 1.95e-17

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 74.54  E-value: 1.95e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   10 GTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDED--RLPWLHAIRQAIEQKQqmgqtAVFTC---SSLKH 84
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEgfRRLESEVLKELLAEHG-----LVIATgggAVLSE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   85 AYREILRANDqdvRFVYLKGSFEVLQKRLAERAD----HFFDPS-LLQTQLDTLEEPSVGEA--IVVDITL-SPRQIIEQ 156
Cdd:pfam01202  77 ENRDLLKERG---IVIYLDAPLEVLLERLKRDKTrpllQNKDPEeELLELLFEERDPLYEEAadIVIDTDEsSPEEVATE 153


                  ....*
gi 491071253  157 VTQKL 161
Cdd:pfam01202 154 ILEAL 158
 
Name Accession Description Interval E-value
GntK COG3265
Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the ...
 1-162 1.81e-90

Gluconate kinase [Carbohydrate transport and metabolism]; Gluconate kinase is part of the Pathway/BioSystem: Non-phosphorylated Entner-Doudoroff pathway


Pssm-ID: 442496 [Multi-domain]  Cd Length: 164  Bit Score: 260.83  E-value: 1.81e-90
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   1 MIVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCS 80
Cdd:COG3265    2 MVIVVMGVSGSGKSTVGQALAERLGWPFIDGDDFHPPANIAKMAAGIPLTDEDRAPWLEALADAIAAHLAAGEGAVLACS 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  81 SLKHAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGE-AIVVDITLSPRQIIEQVTQ 159
Cdd:COG3265   82 ALKRSYRDRLREGNPDVRFVYLDGSRELIAERLAARKGHFMPASLLDSQFATLEPPGPDEdAIVVDIDQPPEEIVAQILA 161


                 ...
gi 491071253 160 KLG 162
Cdd:COG3265  162 ALG 164
GntK cd02021
Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting ...
 2-146 1.64e-67

Gluconate kinase (GntK) catalyzes the phosphoryl transfer from ATP to gluconate. The resulting product gluconate-6-phoshate is an important precursor of gluconate metabolism. GntK acts as a dimmer composed of two identical subunits.


Pssm-ID: 238979 [Multi-domain]  Cd Length: 150  Bit Score: 202.10  E-value: 1.64e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   2 IVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQ-MGQTAVFTCS 80
Cdd:cd02021    1 IIVVMGVSGSGKSTVGKALAERLGAPFIDGDDLHPPANIAKMAAGIPLNDEDRWPWLQALTDALLAKLAsAGEGVVVACS 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  81 SLKHAYREILRAN--DQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGE--AIVVDI 146
Cdd:cd02021   81 ALKRIYRDILRGGaaNPRVRFVHLDGPREVLAERLAARKGHFMPADLLDSQFETLEPPGEDEedVIVIDV 150
therm_gnt_kin TIGR01313
carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of ...
 4-156 1.27e-60

carbohydrate kinase, thermoresistant glucokinase family; This model represents a subfamily of proteins that includes thermoresistant and thermosensitve isozymes of gluconate kinase (gluconokinase) in E. coli and other related proteins; members of this family are often named by similarity to the thermostable isozyme. These proteins show homology to shikimate kinases and adenylate kinases but not to gluconate kinases from the FGGY family of carbohydrate kinases.


Pssm-ID: 273551  Cd Length: 163  Bit Score: 185.30  E-value: 1.27e-60
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253    4 IAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCSSLK 83
Cdd:TIGR01313   2 VLMGVAGSGKSTIASALAHRLGAKFIEGDDLHPAANIEKMSAGIPLNDDDRWPWLQNLNDASTAAAAKNKVGIITCSALK 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 491071253   84 HAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGEA--IVVDITLSPRQIIEQ 156
Cdd:TIGR01313  82 RHYRDILREAEPNLHFIYLSGDKDVILERMKARKGHFMKADMLESQFAALEEPLADETdvLRVDIDQPLEGVEED 156
gntK PRK11545
gluconokinase;
6-157 1.82e-52

gluconokinase;


Pssm-ID: 236926  Cd Length: 163  Bit Score: 164.50  E-value: 1.82e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   6 MGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCSSLKHA 85
Cdd:PRK11545   1 MGVSGSGKSAVASEVAHQLHAAFLDGDFLHPRRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKH 80

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 491071253  86 YREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGEA--IVVDItlspRQIIEQV 157
Cdd:PRK11545  81 YRDLLREGNPNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETdvLVVDI----DQPLEGV 150
idnK PRK09825
gluconokinase;
4-160 8.10e-50

gluconokinase;


Pssm-ID: 182097  Cd Length: 176  Bit Score: 158.27  E-value: 8.10e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   4 IAMGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQMGQTAVFTCSSLK 83
Cdd:PRK09825   7 ILMGVSGSGKSLIGSKIAALFSAKFIDGDDLHPAKNIDKMSQGIPLTDEDRLPWLERLNDASYSLYKKNETGFIVCSSLK 86

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 491071253  84 HAYREILRANDQDVRFVYLKGSFEVLQKRLAERADHFFDPSLLQTQLDTLEEPSVGEAIVVDITLSprQIIEQVTQK 160
Cdd:PRK09825  87 KQYRDILRKSSPNVHFLWLDGDYETILARMQRRAGHFMPPDLLQSQFDALERPCADEHDIARIDVN--HDIENVTEQ 161
SKI pfam01202
Shikimate kinase;
10-161 1.95e-17

Shikimate kinase;


Pssm-ID: 426122 [Multi-domain]  Cd Length: 159  Bit Score: 74.54  E-value: 1.95e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   10 GTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDED--RLPWLHAIRQAIEQKQqmgqtAVFTC---SSLKH 84
Cdd:pfam01202   2 GAGKSTIGRLLAKALGLPFIDTDEEIEKRTGMSIAEIFEEEGEEgfRRLESEVLKELLAEHG-----LVIATgggAVLSE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   85 AYREILRANDqdvRFVYLKGSFEVLQKRLAERAD----HFFDPS-LLQTQLDTLEEPSVGEA--IVVDITL-SPRQIIEQ 156
Cdd:pfam01202  77 ENRDLLKERG---IVIYLDAPLEVLLERLKRDKTrpllQNKDPEeELLELLFEERDPLYEEAadIVIDTDEsSPEEVATE 153


                  ....*
gi 491071253  157 VTQKL 161
Cdd:pfam01202 154 ILEAL 158
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
 3-136 3.43e-11

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 57.70  E-value: 3.43e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253    3 VIAM-GVCGTGKSLIGKLLSERLSCDFLDGDTLHSA-ANKSKMSQGIPLTDEDRLP-WLHAIrqaIEQKQQMGQTAVFTC 79
Cdd:pfam13671   1 LILLvGLPGSGKSTLARRLLEELGAVRLSSDDERKRlFGEGRPSISYYTDATDRTYeRLHEL---ARIALRAGRPVILDA 77

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 491071253   80 SSLKHAYREILR--ANDQDVRF--VYLKGSFEVLQKRLAERADHFFDPSL-----LQTQLDTLEEP 136
Cdd:pfam13671  78 TNLRRDERARLLalAREYGVPVriVVFEAPEEVLRERLAARARAGGDPSDvpeevLDRQKARFEPP 143
CmkB COG1102
Cytidylate kinase [Nucleotide transport and metabolism];
2-116 9.75e-09

Cytidylate kinase [Nucleotide transport and metabolism];


Pssm-ID: 440719 [Multi-domain]  Cd Length: 188  Bit Score: 52.14  E-value: 9.75e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   2 IVIAmGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMS--------QGIPLTDEDRLPWLHAIRQAIEQKQQ--- 70
Cdd:COG1102    3 ITIS-REPGSGGTTIAKRLAEKLGLPLYDGEILREAAKERGLSeeefekldEKAPSLLYRDTAEEDEIDRALDKVIRela 81

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 491071253  71 -------MGQTAVFtcsslkhayreILRANDQDVRfVYLKGSFEVLQKRLAER 116
Cdd:COG1102   82 rkgncviVGRLADW-----------ILRDRPNVLK-VFLTAPLEVRVKRIAER 122
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
2-153 7.93e-08

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 49.14  E-value: 7.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   2 IVIAMGVCGTGKSLIGKLLSERLSCDFLDGDTLhsaaNKSKMSQGIPLTDEDRLPWLHAIRQAIEQKQQM---GQTAVFT 78
Cdd:COG0645    1 LILVCGLPGSGKSTLARALAERLGAVRLRSDVV----RKRLFGAGLAPLERSPEATARTYARLLALARELlaaGRSVILD 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  79 CSSLKHAYRE----ILRANDQDVRFVYLKGSFEVLQKRLAERA----DHFFDPSLLQTQLDTLEEPSVGE--AIVVDITL 148
Cdd:COG0645   77 ATFLRRAQREafraLAEEAGAPFVLIWLDAPEEVLRERLEARNaeggDSDATWEVLERQLAFEEPLTEDEgfLLVVDTSG 156


                 ....*
gi 491071253 149 SPRQI 153
Cdd:COG0645  157 LEEAL 161
AroK COG0703
Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the ...
 10-161 1.75e-07

Shikimate kinase [Amino acid transport and metabolism]; Shikimate kinase is part of the Pathway/BioSystem: Aromatic amino acid biosynthesis


Pssm-ID: 440467 [Multi-domain]  Cd Length: 165  Bit Score: 48.20  E-value: 1.75e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  10 GTGKSLIGKLLSERLSCDFLDGDTLhsAANKSKMSqgIP-LTDEDRLPWLHAI-RQAIEQKQQMGQTAVFTCSS--LKHA 85
Cdd:COG0703    8 GAGKSTVGRLLAKRLGLPFVDTDAE--IEERAGMS--IPeIFAEEGEAGFRELeREVLAELLEEENAVIATGGGavLSPE 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  86 YREILRANDQdVrfVYLKGSFEVLQKRLAERADHffdPsLLQTQ--LDTLEE------PSVGEA--IVVDIT-LSPRQII 154
Cdd:COG0703   84 NRELLKEHGT-V--VYLDASPETLLERLRRDDNR---P-LLQGEdpRERLEEllaerePLYREVadITVDTDgRSPEEVV 156


                 ....*..
gi 491071253 155 EQVTQKL 161
Cdd:COG0703  157 DEILEAL 163
AAA_18 pfam13238
AAA domain;
2-119 7.53e-05

AAA domain;


Pssm-ID: 433052 [Multi-domain]  Cd Length: 128  Bit Score: 40.49  E-value: 7.53e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253    2 IVIAmGVCGTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLT---DEDRLPWLHAIRQAIEQKQQMGQTAVFT 78
Cdd:pfam13238   1 ILIT-GTPGVGKTTLAKELSKRLGFGDNVRDLALENGLVLGDDPETRESkrlDEDKLDRLLDLLEENAALEEGGNLIIDG 79

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 491071253   79 CSS--LKHAYREIlrandqdvRFVYLKGSFEVLQKRLAERADH 119
Cdd:pfam13238  80 HLAelEPERAKDL--------VGIVLRASPEELLERLEKRGYE 114
SK cd00464
Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic ...
 10-135 7.91e-05

Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis of aromatic compounds, such as aromatic amino acids, p-aminobenzoic acid, folate and ubiquinone. Shikimate kinase catalyses the phosphorylation of the 3-hydroxyl group of shikimic acid using ATP.


Pssm-ID: 238260 [Multi-domain]  Cd Length: 154  Bit Score: 40.62  E-value: 7.91e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  10 GTGKSLIGKLLSERLSCDFLDGDTLHSAANKSKMSQGIPLTDEDrlpwlhAIRQaIEQKqqmgqtAVFTCSSLKHA---- 85
Cdd:cd00464    9 GAGKTTVGRLLAKALGLPFVDLDELIEQRAGMSIPEIFAEEGEE------GFRE-LERE------VLLLLLTKENAviat 75

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 491071253  86 ------YREILRANDQDVRFVYLKGSFEVLQKRLAERADHffdPSLLQTQLDTLEE 135
Cdd:cd00464   76 gggavlREENRRLLLENGIVVWLDASPEELLERLARDKTR---PLLQDEDPERLRE 128
aroK PRK00131
shikimate kinase; Reviewed
 6-161 3.31e-04

shikimate kinase; Reviewed


Pssm-ID: 234654 [Multi-domain]  Cd Length: 175  Bit Score: 39.40  E-value: 3.31e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   6 MGVcgtGKSLIGKLLSERLSCDFLDGDTL-HSAANKSkmsqgipltdedrLPWLHAI----------RQAIE---QKQQM 71
Cdd:PRK00131  13 MGA---GKSTIGRLLAKRLGYDFIDTDHLiEARAGKS-------------IPEIFEEegeaafreleEEVLAellARHNL 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  72 ----GQTAVftcssLKHAYREILRANdQDVrfVYLKGSFEVLQKRLAEradhffDPS--LLQTQ--LDTLEE------PS 137
Cdd:PRK00131  77 vistGGGAV-----LREENRALLRER-GTV--VYLDASFEELLRRLRR------DRNrpLLQTNdpKEKLRDlyeerdPL 142

                        170       180
                 ....*....|....*....|....*..
gi 491071253 138 VGEA--IVVDIT-LSPRQIIEQVTQKL 161
Cdd:PRK00131 143 YEEVadITVETDgRSPEEVVNEILEKL 169
APSK cd02027
Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5 ...
 7-112 1.21e-03

Adenosine 5'-phosphosulfate kinase (APSK) catalyzes the phosphorylation of adenosine 5'-phosphosulfate to form 3'-phosphoadenosine 5'-phosphosulfate (PAPS). The end-product PAPS is a biologically "activated" sulfate form important for the assimilation of inorganic sulfate.


Pssm-ID: 238985 [Multi-domain]  Cd Length: 149  Bit Score: 37.46  E-value: 1.21e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253   7 GVCGTGKSLIGKLLSERL-----SCDFLDGDTLHSAANKskmsqGIPLTDEDRlpwLHAIRQAIEQKQQM---GQTAVFT 78
Cdd:cd02027    6 GLSGSGKSTIARALEEKLfqrgrPVYVLDGDNVRHGLNK-----DLGFSREDR---EENIRRIAEVAKLLadaGLIVIAA 77

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 491071253  79 CSSLKHAYREILRANDQDVRF--VYLKGSFEVLQKR 112
Cdd:cd02027   78 FISPYREDREAARKIIGGGDFleVFVDTPLEVCEQR 113
CysC COG0529
Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; ...
 10-112 5.14e-03

Adenylylsulfate kinase or related kinase [Inorganic ion transport and metabolism]; Adenylylsulfate kinase or related kinase is part of the Pathway/BioSystem: Cysteine biosynthesis


Pssm-ID: 440295 [Multi-domain]  Cd Length: 189  Bit Score: 35.84  E-value: 5.14e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 491071253  10 GTGKSLIGKLLSERL-----SCDFLDGDTLHSAANKskmsqGIPLTDEDRLPWlhaIRQAIEQKQQM---GQTAVFTCSS 81
Cdd:COG0529   26 GSGKSTLANALERRLfergrHVYLLDGDNVRHGLNK-----DLGFSKEDRDEN---IRRIGEVAKLLadaGLIVLVAFIS 97

                         90       100       110
                 ....*....|....*....|....*....|...
gi 491071253  82 LKHAYREILRANDQDVRF--VYLKGSFEVLQKR 112
Cdd:COG0529   98 PYRADREEARELIGEGEFieVYVDTPLEVCEAR 130
PRK13947 PRK13947
shikimate kinase; Provisional
 3-34 5.43e-03

shikimate kinase; Provisional


Pssm-ID: 184412 [Multi-domain]  Cd Length: 171  Bit Score: 35.84  E-value: 5.43e-03
                         10        20        30
                 ....*....|....*....|....*....|..
gi 491071253   3 VIAMGVCGTGKSLIGKLLSERLSCDFLDGDTL 34
Cdd:PRK13947   4 IVLIGFMGTGKTTVGKRVATTLSFGFIDTDKE 35
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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