MULTISPECIES: GNAT family N-acetyltransferase [Acinetobacter]
GNAT family N-acetyltransferase( domain architecture ID 10006425)
GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate; similar to Escherichia coli uncharacterized protein YjdJ
List of domain hits
Name | Accession | Description | Interval | E-value | |||
YidJ | COG2388 | Predicted acetyltransferase, GNAT superfamily [General function prediction only]; |
1-91 | 4.61e-26 | |||
Predicted acetyltransferase, GNAT superfamily [General function prediction only]; : Pssm-ID: 441953 [Multi-domain] Cd Length: 88 Bit Score: 91.75 E-value: 4.61e-26
|
|||||||
Name | Accession | Description | Interval | E-value | |||
YidJ | COG2388 | Predicted acetyltransferase, GNAT superfamily [General function prediction only]; |
1-91 | 4.61e-26 | |||
Predicted acetyltransferase, GNAT superfamily [General function prediction only]; Pssm-ID: 441953 [Multi-domain] Cd Length: 88 Bit Score: 91.75 E-value: 4.61e-26
|
|||||||
Acetyltransf_CG | pfam14542 | GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both ... |
13-91 | 8.97e-21 | |||
GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule. Pssm-ID: 434030 [Multi-domain] Cd Length: 79 Bit Score: 78.33 E-value: 8.97e-21
|
|||||||
NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
14-72 | 9.98e-04 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 34.17 E-value: 9.98e-04
|
|||||||
Name | Accession | Description | Interval | E-value | |||
YidJ | COG2388 | Predicted acetyltransferase, GNAT superfamily [General function prediction only]; |
1-91 | 4.61e-26 | |||
Predicted acetyltransferase, GNAT superfamily [General function prediction only]; Pssm-ID: 441953 [Multi-domain] Cd Length: 88 Bit Score: 91.75 E-value: 4.61e-26
|
|||||||
Acetyltransf_CG | pfam14542 | GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both ... |
13-91 | 8.97e-21 | |||
GCN5-related N-acetyl-transferase; This family of GCN5-related N-acetyl-transferases bind both CoA and acetyl-CoA. They are characterized by highly conserved glycine, a cysteine residue in the acetyl-CoA binding site near the acetyl group, their small size compared with other GNATs and a lack of of an obvious substrate-binding site. It is proposed that they transfer an acetyl group from acetyl-CoA to one or more unidentified aliphatic amines via an acetyl (cysteine) enzyme intermediate. The substrate might be another macromolecule. Pssm-ID: 434030 [Multi-domain] Cd Length: 79 Bit Score: 78.33 E-value: 8.97e-21
|
|||||||
ArgA | COG1246 | N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ... |
9-70 | 4.47e-04 | |||
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis Pssm-ID: 440859 [Multi-domain] Cd Length: 132 Bit Score: 36.51 E-value: 4.47e-04
|
|||||||
Acetyltransf_7 | pfam13508 | Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. |
10-81 | 4.75e-04 | |||
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions. Pssm-ID: 463905 [Multi-domain] Cd Length: 84 Bit Score: 35.51 E-value: 4.75e-04
|
|||||||
Acetyltransf_1 | pfam00583 | Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ... |
2-72 | 9.35e-04 | |||
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins. Pssm-ID: 395465 [Multi-domain] Cd Length: 116 Bit Score: 35.57 E-value: 9.35e-04
|
|||||||
NAT_SF | cd04301 | N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ... |
14-72 | 9.98e-04 | |||
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included. Pssm-ID: 173926 [Multi-domain] Cd Length: 65 Bit Score: 34.17 E-value: 9.98e-04
|
|||||||
PhnO | COG0454 | N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ... |
9-79 | 3.39e-03 | |||
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only]; Pssm-ID: 440222 [Multi-domain] Cd Length: 136 Bit Score: 34.26 E-value: 3.39e-03
|
|||||||
Blast search parameters | ||||
|